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Research library: Development

2008: | November | October | September | August | July | June | May | April | March | February | January

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review
From cells to organs: building polarized tissue
David M. Bryant & Keith E. Mostov
Nature Reviews Molecular Cell Biology 9, 887–901
(November 2008); doi:10.1038/nrm2523
| Summary | Full Text (HTML / PDF) |

perspective
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition
Ryoichiro Kageyama, Toshiyuki Ohtsuka, Hiromi Shimojo & Itaru Imayoshi
Nature Neuroscience 11, 1247–1251
(November 2008); doi:10.1038/nn.2208
| Summary | Full Text (HTML / PDF) |

article
Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles
Danelle Devenport & Elaine Fuchs
Nature Cell Biology 10, 1257–1268
(November 2008) doi:10.1038/ncb1784
| Summary | Full Text (HTML / PDF) |

news and views
Bad hair days for mouse PCP mutants
Jeffrey D. Axelrod
Nature Cell Biology 10, 1251–1253
(November 2008); doi:10.1038/ncb1108-1251
| Full Text (HTML / PDF) |

article
Priming for T helper type 2 differentiation by interleukin 2—mediated induction of interleukin 4 receptor α-chain expression
Wei Liao et al.
Nature Immunology 9, 1288–1296
(November 2008); doi:10.1038/ni.1656
| Summary | Full Text (HTML / PDF) |

article
Interactions among the transcription factors Runx1, RORγt and Foxp3 regulate the differentiation of interleukin 17–producing T cells
Fuping Zhang, Guangxun Meng & Warren Strober
Nature Immunology 9, 1297–1306
(November 2008); doi:10.1038/ni.1663
| Summary | Full Text (HTML / PDF) |

article
Lgr5 marks cycling, yet long-lived, hair follicle stem cells
Viljar Jaks et al.
Nature Genetics 40, 1291–1306
(November 2008); doi:10.1038/ng.239
| Summary | Full Text (HTML / PDF) |

news and views
A glorious revolution in stem cell biology
Bruce A Morgan
Nature Genetics 40, 1269–1270
(November 2008); doi:10.1038/ng1108-1269
| Full Text (HTML / PDF) |

letter
d-Asb11 is an essential mediator of canonical Delta—Notch signalling
Sander H. Diks et al.
Nature Cell Biology 10, 1190–1198
(October 2008); doi:10.1038/ncb1779
| Summary | Full Text (HTML / PDF) |

review
IKKα, a critical regulator of epidermal differentiation and a suppressor of skin cancer
Pascal Descargues, Alok K Sil and Michael Karin
The EMBO Journal 27, 2639–2647
(October 2008); doi:10.1038/emboj2008196a
| Summary | Full Text (HTML / PDF) |

letter
Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells
Guonan Lin, Na Xu & Rongwen Xi
Nature 455, 1119–1123
(23 October 2008); doi:10.1038/nature07329
| Summary | Full Text (HTML / PDF) |

article
Notch signaling respecifies the hemangioblast to a cardiac fate
Vincent C Chen, Robert Stull, Daniel Joo, Xin Cheng & Gordon Keller
Nature Biotechnology 26, 1169–1178
(October 2008); doi:10.1038/nbt.1497
| Summary | Full Text (HTML / PDF) |

letter
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla
Jason S. McLellan, Xiaoyan Zheng, Glenn Hauk, Rodolfo Ghirlando, Philip A. Beachy & Daniel J. Leahy
Nature 455, 979–983
(16 October 2008); doi:10.1038/nature07358
| Summary | Full Text (HTML / PDF) |

article
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
Yoichi Maekawa et al.
Nature Immunology 9, 1140–1147
(October 2008); doi:10.1038/ni.1649
| Summary | Full Text (HTML / PDF) |

article
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate
Sawako Muroi et al.
Nature Immunology 9, 1113–1121
(October 2008); doi:10.1038/ni.1650
| Summary | Full Text (HTML / PDF) |

article
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4+ T cells
Lie Wang et al.
Nature Immunology 9, 1122–1130
(October 2008); doi:10.1038/ni.1647
| Summary | Full Text (HTML / PDF) |

article
ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage
Takeshi Egawa & Dan R Littman
Nature Immunology 9, 1131–1139
(October 2008); doi:10.1038/ni.1652
| Summary | Full Text (HTML / PDF) |

news and views
Putting ThPOK in place
J Jeremiah Bell & Avinash Bhandoola
Nature Immunology 9, 1095–1096
(October 2008); doi:10.1038/ni1008-1095;
| Full Text (HTML / PDF) |

letter
A paracrine requirement for hedgehog signalling in cancer
Robert L. Yauch et al.
Nature 455, 406–410
(18 September 2008); doi:10.1038/nature07275
| Summary | Full Text (HTML / PDF) |

news and views
Cancer: Hedgehog's other great trick
Tom Curran & Jessica M. Y. Ng
Nature 455, 293–294
(18 September 2008); doi:10.1038/455293a
| Full Text (HTML / PDF) |

letter
S-nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
Alexi Nott, P. Marc Watson, James D. Robinson, Luca Crepaldi & Antonella Riccio
Nature 455, 411–415
(18 September 2008); doi:10.1038/nature07238
| Summary | Full Text (HTML / PDF) |

letter
ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-β bioavailability regulation
Carine Le Goff et al.
Nature Genetics 40, 1119–1123
(September 2008); doi:10.1038/ng.199
| Summary | Full Text (HTML / PDF) |

review
The genetics of early telencephalon patterning: some assembly required
Jean M. Hébert & Gord Fishell
Nature Reviews Neuroscience 9, 678–685
(September 2008); doi:10.1038/nrn2463
| Summary | Full Text (HTML / PDF) |

review
EvoD/Vo: the origins of BMP signalling in the neuroectoderm
Claudia Mieko Mizutani & Ethan Bier
Nature Reviews Genetics 9, 663–677
(September 2008); doi:10.1038/nrg2417
| Summary | Full Text (HTML / PDF) |

article
Type IV collagens regulate BMP signalling in Drosophila
Xiaomeng Wang, Robin E. Harris, Laura J. Bayston & Hilary L. Ashe
Nature 455, 72–77
(04 September 2008); doi:10.1038/nature07214
| Summary | Full Text (HTML / PDF) |

letter
Mouse development with a single E2F activator
Shih-Yin Tsai et al.
Nature 454, 1137–1141
(28 August 2008); doi:10.1038/nature07066
| Summary | Full Text (HTML / PDF) |

review
The genetics of vertebrate myogenesis
Robert J. Bryson-Richardson & Peter D. Currie
Nature Reviews Genetics 9, 632–646
(August 2008); doi:10.1038/nrg2369
| Summary | Full Text (HTML / PDF) |

article
A conserved face of the Jagged/Serrate DSL domain is involved in Notch trans-activation and cis-inhibition
Jemima Cordle et al.
Nature Structural & Molecular Biology 15, 849–857
(August 2008); doi:10.1038/nsmb.1457
| Summary | Full Text (HTML / PDF) |

article
PRDM16 controls a brown fat/skeletal muscle switch
Patrick Seale et al.
Nature 454, 961–967
(21 August 2008); doi:10.1038/nature07182
| Summary | Full Text (HTML / PDF) |

letter
New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Yu-Hua Tseng et al.
Nature 454, 1000–1004
(21 August 2008); doi:10.1038/nature07221
| Summary | Full Text (HTML / PDF) |

news and views
Developmental biology: Neither fat nor flesh
Barbara Cannon & Jan Nedergaard
Nature 454, 947–948
(21 August 2008); doi:10.1038/454947a
| Full Text (HTML / PDF) |

review
WNT signalling in the immune system: WNT is spreading its wings
Frank J. T. Staal, Tiago C. Luis & Machteld M. Tiemessen
Nature Reviews Immunology 8, 581–593
(August 2008); doi:10.1038/nri2360
| Summary | Full Text (HTML / PDF) |

letter
An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth
Jamie M. Verheyden & Xin Sun
Nature 454, 638–641
(31 July 2008); doi:10.1038/nature07085
| Summary | Full Text (HTML / PDF) |

letter
The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling
Shigeo Takashima, Marianna Mkrtchyan, Amelia Younossi-Hartenstein, John R. Merriam & Volker Hartenstein
Nature 454, 651–655
(31 July 2008); doi:10.1038/nature07156
| Summary | Full Text (HTML / PDF) |

news and views
Developmental biology: Our fly cousins' gut
Chrysoula Pitsouli & Norbert Perrimon
Nature 454, 592–593
(31 July 2008); doi:10.1038/454592a
| Full Text (HTML / PDF) |

letter
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
Morgan E. Carlson, Michael Hsu & Irina M. Conboy
Nature 454, 528–532
(24 July 2008); doi:10.1038/nature07034
| Summary | Full Text (HTML / PDF) |

article
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
Xaralabos Varelas et al.
Nature Cell Biology 10, 837–848
(July 2008); doi:10.1038/ncb1748
| Summary | Full Text (HTML / PDF) |

article
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
Satoshi Uematsu et al.
Nature Immunology 9, 769–776
(July 2008); doi:10.1038/ni.1622
| Summary | Full Text (HTML / PDF) |

letter
IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis
Weidong Zhu et al.
Nature 454, 345–349
(17 July 2008); doi:10.1038/nature07027
| Summary | Full Text (HTML / PDF) |

letter
IL-21 and TGF-β are required for differentiation of human TH17 cells
Li Yang et al.
Nature 454, 350–352
(17 July 2008); doi:10.1038/nature07021
| Summary | Full Text (HTML / PDF) |

brief communication
In vitro whole-organ imaging: 4D quantification of growing mouse limb buds
Marit J Boot et al.
Nature Methods 5, 609–612
(July 2008); doi:10.1038/nmeth.1219
| Summary | Full Text (HTML / PDF) |

letter
Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia
Aline Bozec et al.
Nature 454, 221–225
(10 July 2008); doi:10.1038/nature07019
| Summary | Full Text (HTML / PDF) |

letter
Ras-MAPK signaling promotes trophectoderm formation from embryonic stem cells and mouse embryos
Chi-Wei Lu, Akiko Yabuuchi, Lingyi Chen, Srinivas Viswanathan, Kitai Kim & George Q Daley
Nature Genetics 40, 921–926
doi:10.1038/ng.173
| Summary | Full Text (HTML / PDF) |

review
Retinoic acid in development: towards an integrated view
Karen Niederreither & Pascal Dollé
Nature Reviews Genetics 9, 541–553
doi:10.1038/nrg2340
| Summary | Full Text (HTML / PDF) |

review
A gene regulatory network orchestrates neural crest formation
Tatjana Sauka-Spengler & Marianne Bronner-Fraser
Nature Reviews Molecular Cell Biology 9, 557–568
(July 2008); doi:10.1038/nrm2428
| Summary | Full Text (HTML / PDF) |

article
A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration
Yuzhen Zhang et al.
Nature Genetics 40, 862–870
doi:10.1038/ng.157
| Summary | Full Text (HTML / PDF) |

news and views
Lung stem cells in the balance
Saverio Bellusci
Nature Genetics 40, 822–823
(July 2008); doi:10.1038/ng0708-822
| Full Text (HTML / PDF) |

scientific report
Drosophila RalA is essential for the maintenance of Jak/Stat signalling in ovarian follicles
Christian Ghiglione, Olivier Devergne, Delphine Cerezo & Stéphane Noselli
EMBO reports 9, 676–682
doi:10.1038/embor.2008.79
| Summary | Full Text (HTML / PDF) |

article
Scaling of the BMP activation gradient in Xenopus embryos
Danny Ben-Zvi, Ben-Zion Shilo, Abraham Fainsod & Naama Barkai
Nature 453, 1205–1211
(26 June 2008); doi:10.1038/nature07059
| Summary | Full Text (HTML / PDF) |

letter
β1 Integrin deletion from the basal compartment of the mammary epithelium affects stem cells
Ilaria Taddei et al.
Nature Cell Biology 10, 716–722
doi:10.1038/ncb1734
| Summary | Full Text (HTML / PDF) |

article
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
Nature Immunology 9, 632–640
(June 2008); doi:10.1038/ni.1607
| Summary | Full Text (HTML / PDF) |

article
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nicolas Manel, Derya Unutmaz & Dan R Littman
Nature Immunology 9, 641–649
(June 2008); doi:10.1038/ni.1610
| Summary | Full Text (HTML / PDF) |

article
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
Elisabetta Volpe et al.
Nature Immunology 9, 650–657
(June 2008); doi:10.1038/ni.1613
| Summary | Full Text (HTML / PDF) |

news and views
Differentiation of human TH-17 cells does require TGF-β!
Anne O'Garra, Brigitta Stockinger & Marc Veldhoen
Nature Immunology 9, 588–590
(June 2008); doi:10.1038/ni0608-588
| Full Text (HTML / PDF) |

review
Multiple roles for lipids in the Hedgehog signalling pathway
Suzanne Eaton
Nature Reviews Molecular Cell Biology 9, 437–445
(June 2008); doi:10.1038/nrm2414
| Summary | Full Text (HTML / PDF) |

article
MicroRNA-9 directs late organizer activity of the midbrain-hindbrain boundary
Christoph Leucht et al.
Nature Neuroscience 11, 641–648
(June 2008); doi:10.1038/nn.2115
| Summary | Full Text (HTML / PDF) |

news and views
microRNA-9 multitasking near organizing centers
Celine Delaloy & Fen-Biao Gao
Nature Neuroscience 11, 625–626
(June 2008); doi:10.1038/nn0608-625
| Full Text (HTML / PDF) |

article
The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes
Michaël Mingueneau et al.
Nature Immunology 9, 522–532
(May 2008); doi:10.1038/ni.1608
| Summary | Full Text (HTML / PDF) |

news and views
CD3ε: PeRuSing for positive selection
Jonathan S Maltzman & Gary A Koretzky
Nature Immunology 9, 457–459
(May 2008); doi:10.1038/ni0508-457
| Full Text (HTML / PDF) |

review
Molecular pathogenesis of T-cell leukaemia and lymphoma
Iannis Aifantis, Elizabeth Raetz & Silvia Buonamici
Nature Reviews Immunology 8, 380–390
(May 2008); doi:10.1038/nri2304
| Summary | Full Text (HTML / PDF) |

perspective
Wnt signalling and its impact on development and cancer
Alexandra Klaus & Walter Birchmeier
Nature Reviews Cancer 8, 387–398
(May 2008); doi:10.1038/nrc2389
| Summary | Full Text (HTML / PDF) |

letter
A crucial role of a high mobility group protein HMGA2 in cardiogenesis
Koshiro Monzen et al.
Nature Cell Biology 10, 567–574
(May 2008); doi:10.1038/ncb1719
| Summary | Full Text (HTML / PDF) |

letter
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
Nature Cell Biology 10, 593–601
(May 2008); doi:10.1038/ncb1722
| Summary | Full Text (HTML / PDF) |

news and views
MicroRNAs — keeping cells in formation
Eric A. Miska
Nature Cell Biology 10, 501–502
(May 2008); doi:10.1038/ncb0508-501
| Full Text (HTML / PDF) |

review
TH17 cells in development: an updated view of their molecular identity and genetic programming
Chen Dong
Nature Reviews Immunology 8, 337–348
(May 2008); doi:10.1038/nri2295
| Summary | Full Text (HTML / PDF) |

letter
Genetic evidence that FGFs have an instructive role in limb proximal–distal patterning
Francesca V. Mariani, Christina P. Ahn & Gail R. Martin
Nature 453, 401–405
(15 May 2008); doi:10.1038/nature06876
| Summary | Full Text (HTML / PDF) |

letter
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
Omobolaji O. Akala, In-Kyung Park, Dalong Qian, Michael Pihalja, Michael W. Becker & Michael F. Clarke
Nature 453, 228–232
(8 May 2008); doi:10.1038/nature06869
| Summary | Full Text (HTML / PDF) |

letter
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR γt function
Liang Zhou et al.
Nature 453, 236–240
(8 May 2008); doi:10.1038/nature06878
| Summary | Full Text (HTML / PDF) |

article
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
Francisco J. Quintana et al.
Nature 453, 65–71
(1 May 2008); doi:10.1038/nature06880
| Summary | Full Text (HTML / PDF) |

letter
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
Nature 453, 106–109
(1 May 2008); doi:10.1038/nature06881
| Summary | Full Text (HTML / PDF) |

news and views
Immunology: T cells hang in the balance
Emily A. Stevens & Christopher A. Bradfield
Nature 453, 46–47
(1 May 2008); doi:10.1038/453046a
| Full Text (HTML / PDF) |

letter
Integration of growth and specification in chick wing digit-patterning
Matthew Towers, Ruth Mahood, Yili Yin & Cheryll Tickle
Nature 452, 882–886
(17 April 2008); doi:10.1038/nature06718
| Summary | Full Text (HTML / PDF) |

letter
Retinotopic order in the absence of axon competition
Nathan J. Gosse, Linda M. Nevin & Herwig Baier
Nature 452, 892–895
(17 April 2008); doi:10.1038/nature06816
| Summary | Full Text (HTML / PDF) |

article
Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain
Anju Vasudevan, Jason E Long, James E Crandall, John L R Rubenstein & Pradeep G Bhide
Nature Neuroscience 11, 429–439
(April 2008); doi:10.1038/nn2074
| Summary | Full Text (HTML / PDF) |

letter
Endothelins are vascular-derived axonal guidance cues for developing sympathetic neurons
Takako Makita, Henry M. Sucov, Cheryl E. Gariepy, Masashi Yanagisawa & David D. Ginty
Nature 452, 759–763
(10 April 2008); doi:10.1038/nature06859
| Summary | Full Text (HTML / PDF) |

letter
Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling
Ilaria Malanchi et al.
Nature 452, 650–653
(3 April 2008); doi:10.1038/nature06835
| Summary | Full Text (HTML / PDF) |

review
The role of oxygen availability in embryonic development and stem cell function
M. Celeste Simon & Brian Keith
Nature Reviews Molecular Cell Biology 9, 285–296
(April 2008); doi:10.1038/nrm2354
| Summary | Full Text (HTML / PDF) |

article
The Notch pathway in podocytes plays a role in the development of glomerular disease
Thiruvur Niranjan et al.
Nature Medicine 14, 290–298
(March 2008); doi:10.1038/nm1731
| Summary | Full Text (HTML / PDF) |

news and views
Notch inhibition reverses kidney failure
Matthias Kretzler & Lisa Allred
Nature Medicine 14, 246–247
(March 2008); doi:10.1038/nm0308-246
| Summary | Full Text (HTML / PDF) |

article
MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis
Johann K Eberhart et al.
Nature Genetics 40, 290–298
(March 2008); doi:10.1038/ng.82
| Summary | Full Text (HTML / PDF) |

news and views
MicroRNAs in facial development
David E Clouthier
Nature Genetics 40, 268–269
(March 2008); doi:10.1038/ng0308-268
| Summary | Full Text (HTML / PDF) |

letter
A skin microRNA promotes differentiation by repressing 'stemness'
Rui Yi, Matthew N. Poy, Markus Stoffel & Elaine Fuchs
Nature 452, 225–229
(13 March 2008); doi:10.1038/nature06642
| Summary | Full Text (HTML / PDF) |

article
Retrograde regulation of motoneuron differentiation by muscle β-catenin
Xiao-Ming Li et al.
Nature Neuroscience 11, 262–268
(March 2008); doi:10.1038/nn2053
| Summary | Full Text (HTML / PDF) |

news and views
β-catenin in reverse action
Amy K Y Fu, Zelda H Cheung & Nancy Y Ip
Nature Neuroscience 11, 244–246
(March 2008); doi:10.1038/nn0308-244
| Full Text (HTML / PDF) |

article
A TAG1–APP signalling pathway through Fe65 negatively modulates neurogenesis
Quan-Hong Ma et al.
Nature Cell Biology 10, 283–294
(March 2008); doi:10.1038/ncb1690
| Summary | Full Text (HTML / PDF) |

news and views
TAGing APP constrains neurogenesis
Mark P. Mattson & Henriette van Praag
Nature Cell Biology 10, 249–250
(March 2008); doi:10.1038/ncb0308-249
| Full Text (HTML / PDF) |

review
Small non-coding RNAs in animal development
Giovanni Stefani & Frank J. Slack
Nature Reviews Molecular Cell Biology 9, 219–230
(March 2008); doi:10.1038/nrm2347
| Summary | Full Text (HTML / PDF) |

article
Dimorphic effects of Notch signaling in bone homeostasis
Feyza Engin et al.
Nature Medicine 14, 299–305
(March 2008); doi:10.1038/nm1712
| Summary | Full Text (HTML / PDF) |

article
Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
Matthew J Hilton et al.
Nature Medicine 14, 306–314
(March 2008); doi:10.1038/nm1716
| Summary | Full Text (HTML / PDF) |

perspective
MYC in mammalian epidermis: how can an oncogene stimulate differentiation?
Fiona M. Watt, Michaela Frye & Salvador Aznar Benitah
Nature Reviews Cancer 8, 234–242
(March 2008); doi:10.1038/nrc2328
| Summary | Full Text (HTML / PDF) |

review
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation
Keith W. Orford & David T. Scadden
Nature Reviews Genetics 9, 115–128
(February 2008); doi:10.1038/nrg2269
| Summary | Full Text (HTML / PDF) |

letter
A β-catenin gradient links the clock and wavefront systems in mouse embryo segmentation
Alexander Aulehla et al.
Nature Cell Biology 10, 186–193
(February 2008); doi:10.1038/ncb1679
| Summary | Full Text (HTML / PDF) |

article
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
Jagan M R Pongubala et al.
Nature Immunology 9, 203–215
(February 2008); doi:10.1038/ni1555
| Summary | Full Text (HTML / PDF) |

review
Of lineage and legacy: the development of mammalian hematopoietic stem cells
Elaine Dzierzak & Nancy A Speck
Nature Immunology 9, 129–136
(February 2008); doi:10.1038/ni1560
| Summary | Full Text (HTML / PDF) |

scientific report
CARM1 promotes adipocyte differentiation by coactivating PPARγ
Neelu Yadav et al.
EMBO Reports 9, 193–198
(February 2008); doi:10.1038/sj.embor.7401151
| Summary | Full Text (HTML / PDF) |

letter
Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
Kevin C. Corbit, Amy E. Shyer, William E. Dowdle, Julie Gaulden, Veena Singla & Jeremy F. Reiter
Nature Cell Biology 10, 70–76
(January 2008); doi:10.1038/ncb1670
| Summary | Full Text (HTML / PDF) |

news and views
Cilia put a brake on Wnt signalling
Xi He
Nature Cell Biology 10, 11–13
(January 2008); doi:10.1038/ncb0108-11
| Summary | Full Text (HTML / PDF) |

review
The multifaceted role of Notch in cardiac development and disease
Frances A. High & Jonathan A. Epstein
Nature Reviews Genetics 9, 49–61
(January 2008); doi:10.1038/nrg2279
| Summary | Full Text (HTML / PDF) |

letter
Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
Maksim V. Plikus et al.
Nature 451, 340–344
(17 January 2008); doi:10.1038/nature06457
| Summary | Full Text (HTML / PDF) |

article
The contribution of transcription factor IRF1 to the interferon-γ–interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells
Shin-ichi Kano et al.
Nature Immunology 9, 34–41
(January 2008); doi:10.1038/ni1538
| Summary | Full Text (HTML / PDF) |

news and views
IRF1: a deus ex machina in TH1 differentiation
Derya Unutmaz & Jan Vilcek
Nature Immunology 9, 9–10
(January 2008); doi:10.1038/ni0108-9
| Full Text (HTML / PDF) |

review
Launching the T-cell-lineage developmental programme
Ellen V. Rothenberg, Jonathan E. Moore & Mary A. Yui
Nature Reviews Immunology 8, 9–21
(January 2008); doi:10.1038/nri2232
| Summary | Full Text (HTML / PDF) |

letter
NUMB controls p53 tumour suppressor activity
Ivan N. Colaluca et al.
Nature 451, 76–80
(3 January 2008); doi:10.1038/nature06412
| Summary | Full Text (HTML / PDF) |

article
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Paul B Yu et al.
Nature Chemical Biology 4, 33–41
(January 2008); doi:10.1038/nchembio.2007.54
| Summary | Full Text (HTML / PDF) |

news and views
Small-molecule dissection of BMP signaling
Gregory J Anderson & Deepak Darshan
Nature Chemical Biology 4, 15–16
(January 2008); doi:10.1038/nchembio0108-15
| Full Text (HTML / PDF) |

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