Research library: Diabetes / Obesity
2008:
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June
article
Leptin controls adipose tissue lipogenesis via central, STAT3–independent mechanisms
Christoph Buettner et al.
Nature Medicine 14, 667–675
(June 2008); doi:10.1038/nm1775
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news and views
The long reach of leptin
Eleftheria Maratos-Flier
Nature Medicine 14, 604–606
(June 2008); doi:10.1038/nm0608-604
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review
Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets
Masato Furuhashi & Gökhan S. Hotamisligil
Nature Reviews Drug Discovery 7, 489–503
(June 2008); doi:10.1038/nrd2589
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May
review
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
Adilson Guilherme, Joseph V. Virbasius, Vishwajeet Puri & Michael P. Czech
Nature Reviews Molecular Cell Biology 9, 367–377
(May 2008); doi:10.1038/nrm2391
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April
review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
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review
Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction
Jarl E. S. Wikberg & Felikss Mutulis
Nature Reviews Drug Discovery 7, 307–323
(April 2008); doi:10.1038/nrd2331
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March
article
Variations in DNA elucidate molecular networks that cause disease
Yanqing Chen et al.
Nature 452, 429–435
(27 March 2008); doi:10.1038/nature06757
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review
Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
Deborah M. Muoio & Christopher B. Newgard
Nature Reviews Molecular Cell Biology 9, 193–205
(March 2008); doi:10.1038/nrm2327
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review
Hormones of the gut–brain axis as targets for the treatment of upper gastrointestinal disorders
Gareth J. Sanger & Kevin Lee
Nature Reviews Drug Discovery 7, 241–254
(March 2008); doi:10.1038/nrd2444
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February
article
Dual role of proapoptotic BAD in insulin secretion and beta cell survival
Nika N Danial et al.
Nature Medicine 14, 144–153
(February 2008); doi:10.1038/nm1717
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article
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
Xiaoyong Yang et al.
Nature 451, 964–969
(21 February 2008); doi:10.1038/nature06668
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letter
Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation
Tetsuya Hosooka et al.
Nature Medicine 14, 188–193
(February 2008); doi:10.1038/nm1706
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letter
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim, Junjie Chen & Zhenkun Lou
Nature 451, 583–586
(31 January 2008); doi:10.1038/nature06500
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letter
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu
Nature 451, 587–590
(31 January 2008); doi:10.1038/nature06515
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review
Lipid signalling in disease
Matthias P. Wymann & Roger Schneiter
Nature Reviews Molecular Cell Biology 9, 162–176
(February 2008); doi:10.1038/nrm2335
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