signaling gateway home
registrationelectronic alerthelpcontact ussite guidesearch
cell signaling update signaling update home updates  news  research library featured articles conferences

Research library: Diabetes / Obesity

2009: | December | November | October | September | August | July | May | April | February

Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008

letter
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2
Jose P. Silva et al.
Nature 462, 646–650
(03 December 2009); doi:10.1038/nature08589
| Full Text (HTML / PDF) |

letter
Foxo1 integrates insulin signaling with mitochondrial function in the liver
Zhiyong Cheng et al.
Nature Medicine 15, 1307–1311
(November 2009); doi:10.1038/nm.2049
| Summary | Full Text (HTML / PDF) |

article
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Leona Plum et al.
Nature Medicine 15, 1195–1201
(October 2009); doi:10.1038/nm.2026
| Summary | Full Text (HTML / PDF) |

article
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
Jonathan W Day et al.
Nature Chemical Biology 5, 749–757
(October 2009); doi:10.1038/nchembio.209
| Summary | Full Text (HTML / PDF) |

letter
A crucial role for adipose tissue p53 in the regulation of insulin resistance
Tohru Minamino et al.
Nature Medicine 15, 1082–1087
(September 2009); doi:10.1038/nm.2014
| Summary | Full Text (HTML / PDF) |

news and views
Connecting obesity, aging and diabetes
Rexford S. Ahima
Nature Medicine 15, 996–997
(September 2009); doi:10.1038/nm0909-996
| Full Text (HTML / PDF) |

letter
The CDK4–pRB–E2F1 pathway controls insulin secretion
Jean-Sébastien Annicotte et al.
Nature Cell Biology 11, 1017–1023
(August 2009); doi:10.1038/ncb1915
| Summary | Full Text (HTML / PDF) |

letter
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
Yiguo Wang, Liliana Vera, Wolfgang H. Fischer & Marc Montminy
Nature 460, 534–537
(23 July 2009); doi:10.1038/nature08111
| Full Text (HTML / PDF) |

review
The genetic contribution to non-syndromic human obesity
Andrew J. Walley, Julian E. Asher & Philippe Froguel
Nature Reviews Genetics 10, 431–442
(July 2009); doi:10.1038/nrg2594
| Summary | Full Text (HTML / PDF) |

review
Assessing the potential of glucokinase activators in diabetes therapy
Franz M. Matschinsky
Nature Reviews Drug Discovery 8, 399–416
(May 2009); doi:10.1038/nrd2850
| Summary | Full Text (HTML / PDF) |

review
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes
Bo Ahrén
Nature Reviews Drug Discovery 8, 369–385
(May 2009); doi:10.1038/nrd2782
| Summary | Full Text (HTML / PDF) |

perspective
Therapeutic targets to reduce cardiovascular disease in type 2 diabetes
Cyrus DeSouza & Vivian Fonseca
Nature Reviews Drug Discovery 8, 361–367
(May 2009); doi:10.1038/nrd2872
| Summary | Full Text (HTML / PDF) |

review
Targeting the CNS to treat type 2 diabetes
Darleen A. Sandoval, Silvana Obici & Randy J. Seeley
Nature Reviews Drug Discovery 8, 386–398
(May 2009); doi:10.1038/nrd2874
| Summary | Full Text (HTML / PDF) |

review
Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes
John D. Baxter & Paul Webb
Nature Reviews Drug Discovery 8, 308–320
(April 2009); doi:10.1038/nrd2830
| Summary | Full Text (HTML / PDF) |

letter
Inactivation of the Fto gene protects from obesity
Julia Fischer et al.
Nature 458, 894–898
(16 April 2009); doi:10.1038/nature07848
| Summary | Full Text (HTML / PDF) |

letter
Role of Jhdm2a in regulating metabolic gene expression and obesity resistance
Keisuke Tateishi, Yuki Okada, Eric M. Kallin & Yi Zhang
Nature 458, 757–761
(09 April 2009); doi:10.1038/nature07777
| Summary | Full Text (HTML / PDF) |

article
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
Xia Yang et al.
Nature Genetics 41, 415–423
(April 2009); doi:10.1038/ng.325
| Summary | Full Text (HTML / PDF) |

letter
Deficiency of a β-arrestin-2 signal complex contributes to insulin resistance
Bing Luan et al.
Nature 457, 1146–1149
(26 February 2009); doi:10.1038/nature07617
| Summary | Full Text (HTML / PDF) |

article
AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency
Kathy Jaworski et al.
Nature Medicine 15, 159–168
(February 2009); doi:10.1038/nm.1904
| Summary | Full Text (HTML / PDF) |

 Nature Publishing Group

HOME | SIGNALING UPDATE | MOLECULE PAGES | DATA CENTER | ABOUT US
registration | e-alert | help | contact us | site guide | search

© 2002-2009 Nature Publishing Group

Privacy Policy