news and views Developmental biology: A message to the back side
Wolfgang Driever Nature438, 926–927
(15 December 2005); doi:10.1038/438926b
| Full Text (HTML / PDF) |
article Regulation of Notch signalling by non-visual β-arrestin
Ashim Mukherjee, Alexey Veraksa, Andreas Bauer, Carine Rosse, Jacques Camonis and Spyros Artavanis-Tsakonas Nature Cell Biology7, 1191–1201
(December 2005); doi:10.1038/ncb1327
| Abstract | Full Text (HTML/PDF) |
news and views Receptor regulation: β-arrestin moves up a notch
Sudha K. Shenoy & Robert J. Lefkowitz Nature Cell Biology7, 1159–1161
(December 2005); doi:10.1038/ncb1205-1059
| Full Text (HTML/PDF) |
letter BMP inhibition-driven regulation of six-3 underlies induction of newt lens regeneration
Matthew W. Grogg, Mindy K. Call, Mitsumasa Okamoto, M. Natalia Vergara, Katia Del Rio-Tsonis and Panagiotis A. Tsonis Nature438, 858–862
(08 December 2005); doi:10.1038/nature04175
| First Paragraph | Full Text (HTML / PDF) |
letter Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction
Gary Davidson, Wei Wu, Jinlong Shen, Josipa Bilic, Ursula Fenger, Peter Stannek, Andrei Glinka and Christof Niehrs Nature438, 867–872
(08 December 2005); doi:10.1038/nature04170
| First Paragraph | Full Text (HTML / PDF) |
letter A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
Xin Zeng, Keiko Tamai, Brad Doble, Shitao Li, He Huang, Raymond Habas, Heidi Okamura, Jim Woodgett and Xi He Nature438, 873–877
(08 December 2005); doi:10.1038/nature04185
| First Paragraph | Full Text (HTML / PDF) |
news and views Cell biology: Relays at the membrane
Roel Nusse Nature438, 747–749
(08 December 2005); doi:10.1038/438747a
| Full Text (HTML / PDF) |
review article Signalling in development: Bone morphogenetic protein signalling and vertebrate nervous system development
Aimin Liu and Lee A. Niswander Nature Reviews Neuroscience6, 945–954
(December 2005); doi:10.1038/nrn1805
| Summary | Full Text (HTML / PDF) |
letter The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
Eran Hornstein, Jennifer H. Mansfield, Soraya Yekta, Jimmy Kuang-Hsien Hu, Brian D. Harfe, Michael T. McManus, Scott Baskerville, David P. Bartel and Clifford J. Tabin Nature438, 671–674
(01 December 2005); doi:10.1038/nature04138
| First Paragraph | Full Text (HTML / PDF) |
review article Developmental Cell Biology: Cleavage Pattern and Emerging Asymmetry of the Mouse Embryo
Magdalena Zernicka-Goetz Nature Reviews Molecular Cell Biology6, 919–928
(December 2005); doi:10.1038/nrm1782
| Summary | Full Text (HTML / PDF) |
November
article Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling
Kengo F Kusano, Roberto Pola, Toshinori Murayama, Cynthia Curry, Atsuhiko Kawamoto, Atsushi Iwakura, Satoshi Shintani, Masaaki Ii, Jun Asai, Tengiz Tkebuchava, Tina Thorne, Hideya Takenaka, Ryuichi Aikawa, David Goukassian, Patrick von Samson, Hiromichi Hamada, Young-sup Yoon, Marcy Silver, Elizabeth Eaton, Hong Ma, Lindsay Heyd, Marianne Kearney, William Munger, Jeffery A Porter, Raj Kishore and Douglas W Losordo Nature Medicine11, 1197–1204
(November 2005); doi:10.1038/nm1313
| Abstract | Full Text (HTML/PDF) |
letter Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube
Yuko Muroyama, Yuko Fujiwara, Stuart H. Orkin and David H. Rowitch Nature438, 360–363
(17 November 2005); doi:10.1038/nature04139
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letter A histone H3 methyltransferase controls epigenetic events required for meiotic prophase
Katsuhiko Hayashi , Kayo Yoshida and Yasuhisa Matsui Nature438, 374–378
(17 November 2005); doi:10.1038/nature04112
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review article Developmental cell biology: Regulatory networks in embryo-derived pluripotent stem cells
Michele Boiani and Hans R. Schöler Nature Reviews Molecular Cell Biology6, 872–881
(November 2005); doi:10.1038/nrm1744
| Summary | Full Text (HTML / PDF) |
review article Follicular B helper T cells in antibody responses and autoimmunity
Carola G. Vinuesa, Stuart G. Tangye, Bernhard Moser and Charles R. Mackay Nature Reviews Immunology5, 853–865
(November 2005); doi:10.1038/nri1714
| Summary | Full Text (HTML / PDF) |
review article Building the mammalian heart from two sources of myocardial cells
Margaret Buckingham, Sigolène Meilhac and Stéphane Zaffran Nature Reviews Genetics6, 826–837
(November 2005); doi:10.1038/nrg1710
| Summary | Full Text (HTML / PDF) |
letter Fruitless specifies sexually dimorphic neural circuitry in the Drosophila brain
Ken-Ichi Kimura, Manabu Ote, Tatsunori Tazawa and Daisuke Yamamoto Nature438, 229–233
(10 November 2005); doi:10.1038/nature04229
| First Paragraph | Full Text (HTML / PDF) |
letter Suppression of Polycomb group proteins by JNK signalling induces transdetermination in Drosophila imaginal discs
Nara Lee, Cédric Maurange, Leonie Ringrose and Renato Paro Nature438, 234–237
(10 November 2005); doi:10.1038/nature04120
| First Paragraph | Full Text (HTML / PDF) |
letter A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
Dan Stoleru, Ying Peng, Pipat Nawathean and Michael Rosbash Nature438, 238–242
(10 November 2005); doi:10.1038/nature04192
| First Paragraph | Full Text (HTML / PDF) |
article Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Laurie E Harrington, Robin D Hatton, Paul R Mangan, Henrietta Turner, Theresa L Murphy, Kenneth M Murphy and Casey T Weaver Nature Immunology6, 1123–1132
(November 2005); doi:10.1038/ni1254
| Abstract | Full Text (HTML/PDF) |
article A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park, Zhaoxia Li, Xuexian O Yang, Seon Hee Chang, Roza Nurieva, Yi-Hong Wang, Ying Wang, Leroy Hood, Zhou Zhu, Qiang Tian and Chen Dong Nature Immunology6, 1133–1141
(November 2005); doi:10.1038/ni1261
| Abstract | Full Text (HTML/PDF) |
news and views TH-17: a giant step from TH1 and TH2
Thomas A Wynn Nature Immunology6, 1069–1070
(November 2005); doi:10.1038/ni1105-1069
| Full Text (HTML/PDF) |
letter The transcription factor Engrailed-2 guides retinal axons
Isabelle Brunet, Christine Weinl, Michael Piper, Alain Trembleau, Michel Volovitch, William Harris, Alain Prochiantz and Christine Holt Nature438, 94–98
(03 November 2005); doi:10.1038/nature04110
| First Paragraph | Full Text (HTML / PDF) |
article Cbln1 is essential for synaptic integrity and plasticity in the cerebellum
Hirokazu Hirai, Zhen Pang, Dashi Bao, Taisuke Miyazaki, Leyi Li, Eriko Miura, Jennifer Parris, Yongqi Rong, Masahiko Watanabe, Michisuke Yuzaki and James I Morgan Nature Neuroscience8, 1534–1541
(November 2005); doi:10.1038/nn1576
| Abstract
| Full Text (HTML / PDF) |
October
letter Regulation of Lethal giant larvae by Dishevelled
Gretchen L. Dollar, Ursula Weber, Marek Mlodzik and Sergei Y. Sokol Nature437, 1376–1380
(27 October 2005); doi:10.1038/nature04116
| First Paragraph | Full Text (HTML / PDF) |
brief communication Homozygous HOXA1 mutations disrupt human brainstem, inner ear, cardiovascular and cognitive development
Max A Tischfield, Thomas M Bosley, Mustafa A M Salih, Ibrahim A Alorainy, Emin C Sener, Michael J Nester, Darren T Oystreck, Wai-Man Chan, Caroline Andrews, Robert P Erickson and Elizabeth C Engle Nature Genetics37, 1035–1037
(October 2005); doi:10.1038/ng1636
| First Paragraph | Full Text (HTML/PDF) |
letter Vertebrate Smoothened functions at the primary cilium
Kevin C. Corbit, Pia Aanstad , Veena Singla, Andrew R. Norman, Didier Y. R. Stainier and Jeremy F. Reiter Nature437, 1018–1021
(13 October 2005); doi:10.1038/nature04117
| First Paragraph | Full Text (HTML / PDF) |
letter SERRATE coordinates shoot meristem function and leaf axial patterning in Arabidopsis
Stephen P. Grigg, Claudia Canales, Angela Hay and Miltos Tsiantis Nature437, 1022–1026
(13 October 2005); doi:10.1038/nature04052
| First Paragraph | Full Text (HTML / PDF) |
news and views Developmental biology: Cell cycle unleashed
Takeo Kishimoto Nature437, 963–965
(13 October 2005); doi:10.1038/437963a
| Full Text (HTML / PDF) |
letter Abi activates WASP to promote sensory organ development
Sven Bogdan, Raiko Stephan, Christian Löbke, Alexandra Mertens and Christian Klämbt Nature Cell Biology7, 977–984
(October 2005); doi:10.1038/ncb1305
| First Paragraph | Full Text (HTML/PDF) |
article Apoptosis induced by vitamin A signaling is crucial for connecting the ureters to the bladder
Ekatherina Batourina, Sheaumei Tsai, Sarah Lambert, Preston Sprenkle, Renata Viana, Sonia Dutta, Terry Hensle, Fengwei Wang, Karen Niederreither, Andrew P McMahon, Thomas J Carroll and Cathy L Mendelsohn Nature Genetics37, 1082–1089
(October 2005); doi:10.1038/ng1645
| Abstract | Full Text (HTML/PDF) |
article SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor
Josana Rodriguez, Pilar Esteve, Christine Weinl, José María Ruiz, Yasmín Fermin, Françoise Trousse, Asha Dwivedy, Christine Holt and Paola Bovolenta Nature Neuroscience8, 1301–1309
(October 2005); doi:10.1038/nn1547
| Abstract | Full Text (HTML/PDF) |
news and views A no-Wnt situation: SFRPs as axon guidance molecules
Uwe Drescher Nature Neuroscience8, 1281–1282
(October 2005); doi:10.1038/nn1005-1281
| Full Text (HTML/PDF) |
news and views Fog shapes up myosin for gastrulation Nature Cell Biology7, 935
(October 2005); doi:10.1038/ncb1005-935
| Full Text (HTML/PDF) |
September
letter WntD is a feedback inhibitor of Dorsal/NF-κB in Drosophila development and immunity
Michael D. Gordon, Marc S. Dionne, David S. Schneider and Roel Nusse Nature437, 746–749
(29 September 2005); doi:10.1038/nature04073
| First Paragraph | Full Text (HTML / PDF) |
letter Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway
Jianbo Wang, Sharayne Mark, Xiaohui Zhang, Dong Qian, Seung-Jong Yoo, Kristen Radde-Gallwitz, Yanping Zhang, Xi Lin, Andres Collazo, Anthony Wynshaw-Boris and Ping Chen Nature Genetics37, 980–985
(September 2005); doi:10.1038/ng1622
| First Paragraph | Full Text (HTML/PDF) |
article Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
Xiuxin Liu, Qin Wang, Tarik F Haydar and Angélique Bordey Nature Neuroscience8, 1179–1187
(September 2005); doi:10.1038/nn1522
| Abstract | Full Text (HTML/PDF) |
review article The origin and development of glial cells in peripheral nerves
Kristjan R. Jessen and Rhona Mirsky Nature Reviews Neuroscience6, 671–682
(September 2005); doi:10.1038/nrn1746
| Abstract | Full Text (HTML / PDF) |
article PDGFRβ+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
Steven Song, Andrew J. Ewald, William Stallcup, Zena Werb and Gabriele Bergers Nature Cell Biology7, 870–879
(September 2005); doi:10.1038/ncb1288
| Abstract | Full Text (HTML/PDF) |
review article Developmental Cell Biology: G Proteins in Development
Craig C. Malbon Nature Reviews Molecular Cell Biology6, 689–701
(September 2005); doi:10.1038/nrm1716
| Abstract | Full Text (HTML / PDF) |
article Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
Xiaofeng Li, Peng Liu, Wenzhong Liu, Peter Maye, Jianghong Zhang, Yazhou Zhang, Marja Hurley, Caiying Guo, Adele Boskey, Le Sun, Stephen E Harris, David W Rowe, Hua Zhu Ke and Dianqing Wu Nature Genetics37, 945–952
(September 2005); doi:10.1038/ng1614
| Abstract | Full Text (HTML/PDF) |
August
letter Role of nucleophosmin in embryonic development and tumorigenesis
Silvia Grisendi, Rosa Bernardi, Marco Rossi, Ke Cheng, Luipa Khandker, Katia Manova and Pier Paolo Pandolfi Nature437, 147–153
(01 September 2005); doi:10.1038/nature03915
| First Paragraph | Full Text (HTML / PDF) |
letter Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
Rebecca A. Wingert, Jenna L. Galloway, Bruce Barut, Helen Foott, Paula Fraenkel, Jennifer L. Axe, Gerhard J. Weber, Kimberly Dooley, Alan J. Davidson, Bettina Schmidt, Barry H. Paw, George C. Shaw, Paul Kingsley, James Palis, Heidi Schubert, Opal Chen, Jerry Kaplan, The Tübingen 2000 Screen Consortium and Leonard I. Zon Nature436, 1035–1039
(18 August 2005); doi:10.1038/nature03887
| First Paragraph | Full Text (HTML / PDF) |
July
letter Somatic control of germline sexual development is mediated by the JAK/STAT pathway
Matthew Wawersik, Allison Milutinovich, Abbie L. Casper, Erika Matunis, Brian Williams and Mark Van Doren Nature436, 563–567
(28 July 2005); doi:10.1038/nature03849
| First Paragraph | Full Text (HTML / PDF) |
review article Heparan sulphate proteoglycans: the sweet side of
development Udo Häcker, Kent Nybakken and Norbert Perrimon Nature
Reviews Molecular Cell Biology6, 530–541 (July 2005);
doi:10.1038/nrm1681 | Abstract | Full Text (HTML /
PDF) |
article Notch signaling
controls the generation and differentiation of early T lineage
progenitors Arivazhagan Sambandam, Ivan Maillard, Valerie P Zediak,
Lanwei Xu, Rachel M Gerstein, Jon C Aster, Warren S Pear and Avinash
Bhandoola Nature Immunology6, 663–670 (July 2005);
doi:10.1038/ni1216 | Abstract | Full Text (HTML/PDF)
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article Requirement for Notch1
signals at sequential early stages of intrathymic T cell
development Joanne B Tan, Ioana Visan, Julie S Yuan and Cynthia J
Guidos Nature Immunology6, 671–679 (July 2005);
doi:10.1038/ni1217 | Abstract | Full Text (HTML/PDF)
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article Inhibitors of
γ-secretase block in vivo and in vitro T helper type 1
polarization by preventing Notch upregulation of Tbx21 Lisa M
Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G
Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer, Lisa
Kostura, Abdul H Fauq, Katherine Simpson, Kimberly A Such, Lucio Miele, Todd E
Golde, Stephen D Miller and Barbara A Osborne Nature Immunology6, 680–688 (July 2005); doi:10.1038/ni1209 | Abstract | Full Text (HTML/PDF)
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news and views Notch in
lymphopoiesis and T cell polarization Harald von Boehmer Nature
Immunology6, 641–642 (July 2005); doi:10.1038/ni0705-641 | Full Text
(HTML/PDF) |
brief communication Loss of
mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal
achalasia Takaharu Taketomi, Daigo Yoshiga, Koji Taniguchi, Takashi
Kobayashi, Atsushi Nonami, Reiko Kato, Mika Sasaki, Atsuo Sasaki, Hitoshi
Ishibashi, Maiko Moriyama, Kei-ichiro Nakamura, Junji Nishimura and Akihiko
Yoshimura Nature Neuroscience8, 855–857 (July 2005);
doi:10.1038/nn1485 | First Paragraph | Full Text (HTML/PDF)
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news and views Proteomics takes
stem cell analyses to another level Andre Levchenko Nature
Biotechnology23, 828–830 (July 2005);
doi:10.1038/nbt0705-828 | Full Text
(HTML/PDF)
article Blimp1 is a critical determinant of the germ cell lineage in mice
Yasuhide Ohinata , Bernhard Payer , Dónal O'Carroll , Katia Ancelin , Yukiko Ono , Mitsue Sano , Sheila C. Barton , Tetyana Obukhanych , Michel Nussenzweig , Alexander Tarakhovsky , Mitinori Saitou and M. Azim Surani Nature436, 207–213
(14 July 2005); doi:10.1038/nature03813
| Summary | Full Text (HTML / PDF) |
article Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
Yong Zhao , Eva Samal and Deepak Srivastava Nature436, 214–220
(14 July 2005); doi:10.1038/nature03817
| Summary | Full Text (HTML / PDF) |
news and views Developmental biology: Tiny brakes for a growing heart
Benoit G. Bruneau Nature436, 181–182
(14 July 2005); doi:10.1038/436181a
| Full Text (HTML / PDF) |
review article Common mechanisms of nerve and blood vessel wiring
Peter Carmeliet and Marc Tessier-Lavigne Nature436, 193–200
(14 July 2005); doi:10.1038/nature03875
| Summary | Full Text (HTML / PDF) |
letter The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate
Monica Dentice, Amitabha Bandyopadhyay, Balázs Gereben, Isabelle Callebaut, Marcelo A. Christoffolete, Brian W. Kim, Sahar Nissim, Jean-Paul Mornon, Ann Marie Zavacki, Anikó Zeöld, Luciane P. Capelo, Cyntia Curcio-Morelli, Rogério Ribeiro, John W. Harney, Clifford J. Tabin and Antonio C. Bianco Nature Cell Biology7, 698–705
(July 2005); doi:10.1038/ncb1272
| First Paragraph | Full Text (HTML/PDF) |
article DNER acts as a neuron-specific Notch ligand during Bergmann glial development
Mototsugu Eiraku, Akira Tohgo, Katsuhiko Ono, Megumi Kaneko, Kazuto Fujishima, Tomoo Hirano and Mineko Kengaku Nature Neuroscience8, 873–880
(July 2005); doi:10.1038/nn1492
| Abstract | Full Text (HTML/PDF) |
June
letter Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
Johan H. van Es, Marielle E. van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J. Winton, Freddy Radtke and Hans Clevers Nature435, 959–963
(16 June 2005); doi:10.1038/nature03659
| First Paragraph | Full Text (HTML / PDF) |
letter Notch signals control the fate of immature progenitor cells in the intestine
Silvia Fre, Mathilde Huyghe, Philippos Mourikis, Sylvie Robine, Daniel Louvard and Spyros Artavanis-Tsakonas Nature435, 964–968
(16 June 2005); doi:10.1038/nature03589
| First Paragraph | Full Text (HTML / PDF) |
article LINGO-1 negatively regulates myelination by oligodendrocytes
Sha Mi, Robert H Miller, Xinhua Lee, Martin L Scott, Svetlane Shulag-Morskaya, Zhaohui Shao, Jufang Chang, Greg Thill, Melissa Levesque, Mingdi Zhang, Cathy Hession, Dinah Sah, Bruce Trapp, Zhigang He, Vincent Jung, John M McCoy and R Blake Pepinsky Nature Neuroscience8, 745–751
(June 2005); doi:10.1038/nn1460
| Abstract | Full Text (HTML/PDF) |
article Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
Yu-Hua Tseng, Atul J. Butte, Efi Kokkotou, Vijay K. Yechoor, Cullen M. Taniguchi, Kristina M. Kriauciunas, Aaron M. Cypess, Michio Niinobe, Kazuaki Yoshikawa, Mary Elizabeth Patti and C. Ronald Kahn Nature Cell Biology7, 601–611
(June 2005); doi:10.1038/ncb1259
| Abstract | Full Text (HTML/PDF) |
news and views Fickle factor foils fat fate
Ormond A. MacDougald and Charles F. Burant Nature Cell Biology7, 543–545
(June 2005); doi:10.1038/ncb0605-543
| Full Text (HTML/PDF) |
review article Transcriptional networks in developing and mature B cells
Patrick Matthias and Antonius G. Rolink Nature Reviews Immunology5, 497–508
(June 2005); doi:10.1038/nri1633
| Summary | Full Text (HTML / PDF) |
article TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells
Stephan R Krutzik, Belinda Tan, Huiying Li, Maria Teresa Ochoa, Philip T Liu, Sarah E Sharfstein, Thomas G Graeber, Peter A Sieling, Yong-Jun Liu, Thomas H Rea, Barry R Bloom and Robert L Modlin Nature Medicine11, 653–660
(June 2005); doi:10.1038/nm1246
| Abstract | Full Text (HTML/PDF) |
article Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ
Yasmina Laouar, Fayyaz S Sutterwala, Leonid Gorelik and Richard A Flavell Nature Immunology6, 600–607
(June 2005); doi:10.1038/ni1197
| Abstract | Full Text (HTML/PDF) |
review article Control of lymphocyte development by nuclear factor-κB
Ulrich Siebenlist, Keith Brown and Estefania Claudio Nature Reviews Immunology5, 435–445
(June 2005); doi:10.1038/nri1629
| Summary | Full Text (HTML / PDF) |
May
letters to nature Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
Li-Ru You, Fu-Jung Lin, Christopher T. Lee, Francesco J. DeMayo, Ming-Jer Tsai and Sophia Y. Tsai Nature435, 98–104
(05 May 2005); doi:10.1038/nature03511
| First Paragraph | Full Text (HTML / PDF) |
letter The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity
Mitsuru Morimoto, Yu Takahashi, Maho Endo and Yumiko Saga Nature435, 354–359
(19 May 2005); doi:10.1038/nature03591
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article Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo
Yasuhiko Kawakami, Ángel Raya, R. Marina Raya, Concepción Rodríguez-Esteban and Juan Carlos Izpisúa Belmonte Nature435, 165–171
(12 May 2005); doi:10.1038/nature03512
| Summary | Full Text (HTML / PDF) |
news and views Developmental biology: Asymmetrical threat averted
Eran Hornstein and Clifford J. Tabin Nature435, 155–156
(12 May 2005); doi:10.1038/435155a
| Full Text (HTML / PDF) |
article FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
Yosuke Tanaka, Yasushi Okada and Nobutaka Hirokawa Nature435, 172–177
(12 May 2005); doi:10.1038/nature03494
| Summary | Full Text (HTML / PDF) |
letters to nature Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos
Julien Vermot and Olivier Pourquié ′Nature435, 215–220
(12 May 2005); doi:10.1038/nature03488
| First Paragraph | Full Text (HTML / PDF) |
article Lipoprotein particles are required for Hedgehog and Wingless signalling
Daniela Panáková, Hein Sprong, Eric Marois, Christoph Thiele and Suzanne Eaton Nature435, 58–65
(05 May 2005); doi:10.1038/nature03504
| Summary | Full Text (HTML / PDF) |
news and views Developmental biology: Morphogens hitch a greasy ride
Richard S. Mann and Joaquim Culi Nature435, 30–33
(05 May 2005); doi:10.1038/435030a
| Full Text (HTML / PDF) |
article Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
Wenjun Cheng, Jinsong Liu, Hiroyuki Yoshida, Daniel Rosen and Honami Naora Nature Medicine11, 531–537
(May 2005); doi:10.1038/nm1230
| Abstract | Full Text (HTML/PDF) |
article Quantitative analysis of gene expression in living adult neural stem cells by gene trapping
John R Scheel, Jasodhara Ray, Fred H Gage and Carrolee Barlow Nature Methods2, 363–370
(May 2005); doi:10.1038/nmeth755
| Abstract | Full Text (HTML/PDF) |
research article Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
Viviane Tabar, Georgia Panagiotakos, Edward D Greenberg, Bill K Chan, Michel Sadelain, Philip H Gutin and Lorenz Studer Nature Biotechnology23, 601–606
(May 2005); doi:10.1038/nbt1088
| First Paragraph | Full Text (HTML/PDF) |
research article Transient inhibition of BMP signaling by Noggin induces cardiomyocyte differentiation of mouse embryonic stem cells
Shinsuke Yuasa, Yuji Itabashi, Uichi Koshimizu, Tomofumi Tanaka, Keijiro Sugimura, Masayoshi Kinoshita, Fumiyuki Hattori, Shin-ichi Fukami, Takuya Shimazaki, Hideyuki Okano, Satoshi Ogawa and Keiichi Fukuda Nature Biotechnology23, 607–611
(May 2005); doi:10.1038/nbt1093
| First Paragraph | Full Text (HTML/PDF) |
article The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium
Junlin Teng, Tatemitsu Rai, Yosuke Tanaka, Yosuke Takei, Takao Nakata, Motoyuki Hirasawa, Ashok B. Kulkarni and Nobutaka Hirokawa Nature Cell Biology7, 474–482
(May 2005); doi:10.1038/ncb1249
| Abstract | Full Text (HTML/PDF) |
news and views When domestiques rebel: kinesins, cadherins and neuronal proliferation
Cara J. Gottardi, Nicole R. den Elzen and Alpha S. Yap Nature Cell Biology7, 445–447
(May 2005); doi:10.1038/ncb0505-445
| Full Text (HTML/PDF) |
letter Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
Matias Simons, Joachim Gloy, Athina Ganner, Axel Bullerkotte, Mikhail Bashkurov, Corinna Krönig, Bernhard Schermer, Thomas Benzing, Olga A Cabello, Andreas Jenny, Marek Mlodzik, Bozena Polok, Wolfgang Driever, Tomoko Obara and Gerd Walz Nature Genetics37, 537–543
(May 2005); doi:10.1038/ng1552
| First Paragraph | Full Text (HTML/PDF) |
news and views Linking cilia to Wnts
Gregory G Germino Nature Genetics37, 455–457
(May 2005); doi:10.1038/ng0505-455
| Full Text (HTML/PDF) |
letter Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila
Isabelle E. Bécam, Guy Tanentzapf, Jean-Antoine Lepesant, Nicholas H. Brown and Jean-René Huynh Nature Cell Biology7, 510–516
(May 2005); doi:10.1038/ncb1253
| First Paragraph | Full Text (HTML/PDF) |
news and views Talin's second persona
Ulrich Tepass and Dorothea Godt Nature Cell Biology7, 443–444
(May 2005); doi:10.1038/ncb0505-443
| Full Text (HTML/PDF) |
news and views Dpp gets in shape
Alison Schuldt Nature Cell Biology7, 456
(May 2005); doi:10.1038/ncb0505-456
| Full Text (HTML/PDF) |
review article WNTS in the vertebrate nervous system: from patterning to neuronal connectivity
Lorenza Ciani and Patricia C. Salinas Nature Reviews Neuroscience6, 351–362
(May 2005); doi:10.1038/nrn1665
| Summary | Full Text (HTML / PDF) |
article A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis
Fei He, Weihong Ge, Keri Martinowich, Sara Becker-Catania, Volkan Coskun, Wenyu Zhu, Hao Wu, Diogo Castro, Francois Guillemot, Guoping Fan, Jean de Vellis and Yi E Sun Nature Neuroscience8, 616–625
(May 2005); doi:10.1038/nn1440
| Abstract | Full Text (HTML/PDF) |
April
letters to nature Regulation of axon growth in vivo by activity-based competition
Jackie Yuanyuan Hua, Matthew C. Smear, Herwig Baier and Stephen J. Smith Nature434, 1022–1026
(21 April 2005); doi:10.1038/nature03409
| First Paragraph | Full Text (HTML / PDF) |
news and views Neurobiology: Sculpted by competition
Ole Petter Ottersen Nature434, 969
(21 April 2005); doi:10.1038/434969a
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letter Wnt signalling induces maturation of Paneth cells in intestinal crypts
Johan H. van Es, Philippe Jay, Alex Gregorieff, Marielle E. van Gijn, Suzanne Jonkheer, Pantelis Hatzis, Andrea Thiele, Maaike van den Born, Harry Begthel, Thomas Brabletz, Makoto M. Taketo and Hans Clevers Nature Cell Biology7, 381–386
(April 2005); doi:10.1038/ncb1240
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article Immune activation modulates hematopoiesis through interactions between CD27 and CD70
Martijn A Nolte, Ramon Arens, Ronald van Os, Michiel van Oosterwijk, Berend Hooibrink, René A W van Lier and Marinus H J van Oers Nature Immunology6, 412–418
(April 2005); doi:10.1038/ni1174
| Abstract | Full Text (HTML/PDF) |
review article TEC-family kinases: regulators of T-helper-cell differentiation
Pamela L. Schwartzberg, Lisa D. Finkelstein and Julie A. Readinger Nature Reviews Immunology5, 284–295
(April 2005); doi:10.1038/nri1591
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article The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
Guangping Sun, Xiaolong Liu, Peter Mercado, S Rhiannon Jenkinson, Magdalini Kypriotou, Lionel Feigenbaum, Philippe Galéra and Rémy Bosselut Nature Immunology6, 373–381
(April 2005); doi:10.1038/ni1183
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news and views Switching sides: transcriptional control of CD4 thymocyte lineage commitment
Rose Zamoyska Nature Immunology6, 363–364
(April 2005); doi:10.1038/ni0405-363
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brief communication The hESC line Envy expresses high levels of GFP in all differentiated progeny
Magdaline Costa, Mirella Dottori, Elizabeth Ng, Susan M Hawes, Koula Sourris, Pegah Jamshidi, Martin F Pera, Andrew G Elefanty and Edouard G Stanley Nature Methods2, 259–260
(April 2005); doi:10.1038/nmeth748
| Abstract | Full Text (HTML/PDF) |
perspectives Timeline: Leukaemia stem cells and the evolution of cancer-stem-cell research
Brian J. P. Huntly and D. Gary Gilliland Nature Reviews Cancer5, 311–321
(April 2005); doi:10.1038/nrc1592
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article Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
Andrew W Duncan, Frédérique M Rattis, Leah N DiMascio, Kendra L Congdon, Gregory Pazianos, Chen Zhao, Keejung Yoon, J Michael Cook, Karl Willert, Nicholas Gaiano and Tannishtha Reya Nature Immunology6, 314–322
(March 2005); doi:10.1038/ni1164
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news and views Defining 'stemness': Notch and Wnt join forces?
Sten Eirik W Jacobsen Nature Immunology6, 234–236
(March 2005); doi:10.1038/ni0305-234
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article LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses
Anthone W Dunah, Emily Hueske, Michael Wyszynski, Casper C Hoogenraad, Jacek Jaworski, Daniel T Pak, Alyson Simonetta, Guosong Liu and Morgan Sheng Nature Neuroscience8, 458–467
(April 2005); doi:10.1038/nn1416
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review article Developmental Cell Biology: Communicating with Hedgehogs
Joan E. Hooper and Matthew P. Scott Nature Reviews Molecular Cell Biology6, 306–317
(April 2005); doi:10.1038/nrm1612
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article Protocadherin Celsr3 is crucial in axonal tract development
Fadel Tissir, Isabelle Bar, Yves Jossin and Andre M Goffinet Nature Neuroscience8, 451–457
(April 2005); doi:10.1038/nn1428
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review article A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
Jason D Fontenot and Alexander Y Rudensky Nature Immunology6, 331–337
(April 2005); doi:10.1038/ni1179
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letter Regulation of NKT cell development by SAP, the protein defective in XLP
Kim E Nichols, Jamie Hom, Shun-You Gong, Arupa Ganguly, Cindy S Ma, Jennifer L Cannons, Stuart G Tangye, Pamela L Schwartzberg, Gary A Koretzky and Paul L Stein Nature Medicine11, 340–345
(March 2005); doi:10.1038/nm1189
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news and views The need for natural killer T cells
H Robson MacDonald and Jens Schümann Nature Medicine11, 256–257
(March 2005); doi:10.1038/nm0305-256
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article Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord
Dimitris Bourikas, Vladimir Pekarik, Thomas Baeriswyl, Åsa Grunditz, Rejina Sadhu, Michele Nardó and Esther T Stoeckli Nature Neuroscience8, 297–304
(March 2005); doi:10.1038/nn1396
| Abstract | Full Text (HTML/PDF) |
March
letters to nature Leptin regulation of bone resorption by the sympathetic nervous system and CART
Florent Elefteriou , Jong Deok Ahn, Shu Takeda , Michael Starbuck, Xiangli Yang, Xiuyun Liu, Hisataka Kondo, William G. Richards, Tony W. Bannon, Masaki Noda, Karine Clement, Christian Vaisse and Gerard Karsenty Nature434, 514–520
(24 March 2005); doi:10.1038/nature03398
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news and views Physiology: Do neural signals remodel bone?
Joel K. Elmquist and Gordon J. Strewler Nature434, 447–448
(24 March 2005); doi:10.1038/434447a
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letters to nature Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1
Jérôme Déjardin, Aurélien Rappailles, Olivier Cuvier, Charlotte Grimaud, Martine Decoville, Daniel Locker and Giacomo Cavalli Nature434, 533–538
(24 March 2005); doi:10.1038/nature03386
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letters to nature Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning
Yu-Chiun Wang and Edwin L. Ferguson Nature434, 229–234
(10 March 2005); doi:10.1038/nature03318
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review article The floor plate: multiple cells, multiple signals
Marysia Placzek and James Briscoe Nature Reviews Neuroscience6, 230–240
(March 2005); doi:10.1038/nrn1628
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review article Regulation of plasma-cell development
Miriam Shapiro-Shelef and Kathryn Calame Nature Reviews Immunology5, 230–242
(March 2005); doi:10.1038/nri1572
| Summary | Full Text (HTML / PDF) |
letter Conservation and diversification of Wnt signaling function during the evolution of nematode vulva development
Min Zheng, Daniel Messerschmidt, Benno Jungblut and Ralf J Sommer Nature Genetics37, 300–304
(March 2005); doi:10.1038/ng1512
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article Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
Ren-He Xu, Ruthann M Peck, Dong S Li, Xuezhu Feng, Tenneille Ludwig and James A Thomson Nature Methods2, 185–190
(March 2005); doi:10.1038/nmeth744
| Abstract | Full Text (HTML/PDF) |
news and views Stem cell culture, one step at a time
Martin F Pera Nature Methods2, 164–165
(March 2005); doi:10.1038/nmeth0305-164
| Abstract | Full Text (HTML/PDF) |
article STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
Ferenc A Scheeren, Marianne Naspetti, Sean Diehl, Remko Schotte, Maho Nagasawa, Erwin Wijnands, Ramon Gimeno, Florry A Vyth-Dreese, Bianca Blom and Hergen Spits Nature Immunology6, 303–313
(March 2005); doi:10.1038/ni1172
| Abstract | Full Text (HTML/PDF) |
article Soluble CPG15 expressed during early development rescues cortical progenitors from apoptosis
Ulrich Putz, Corey Harwell and Elly Nedivi Nature Neuroscience8, 322–331
(March 2005); doi:10.1038/nn1407
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letter Atrophy of S6K1−/− skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control
Mickaël Ohanna, Andrew K. Sobering, Thomas Lapointe, Lazaro Lorenzo, Christophe Praud, Emmanuel Petroulakis, Nahum Sonenberg, Paul A. Kelly, Athanassia Sotiropoulos and Mario Pende Nature Cell Biology7, 286–294
(March 2005); doi:10.1038/ncb1231
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review article The floor plate: multiple cells, multiple signals
Marysia Placzek and James Briscoe Nature Reviews Neuroscience6, 230–240
(March 2005); doi:10.1038/nrn1628
| Summary | Full Text (HTML / PDF) |
letter Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
Savraj S. Grewal, Ling Li, Amir Orian, Robert N. Eisenman and Bruce A. Edgar Nature Cell Biology7, 295–302
(March 2005); doi:10.1038/ncb1223
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February
article The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
Xiao He, Xi He, Vibhuti P. Dave, Yi Zhang, Xiang Hua, Emmanuelle Nicolas, Weihong Xu, Bruce A. Roe and Dietmar J. Kappes Nature433, 826–833
(24 February 2005); doi:10.1038/nature03338
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letters to nature Pax3 functions at a nodal point in melanocyte stem cell differentiation
Deborah Lang, Min Min Lu, Li Huang, Kurt A. Engleka, Maozhen Zhang, Emily Y. Chu, Shari Lipner, Arthur Skoultchi, Sarah E. Millar and Jonathan A. Epstein Nature433, 884–887
(24 February 2005); doi:10.1038/nature03292
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news and views Immunology: Guide for a cell-fate decision
Ellen A. Robey Nature433, 813–814
(24 February 2005); doi:10.1038/433813a
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letter Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells
Carl R. Walkley, Matthew L. Fero, Wei-Ming Chien, Louise E. Purton and Grant A. McArthur Nature Cell Biology7, 172–178
(February 2005); doi:10.1038/ncb1214
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review article Roles of interferon-regulatory factors in T-helper-cell differentiation
Michael Lohoff and Tak W. Mak Nature Reviews Immunology5, 125–135
(February 2005); doi:10.1038/nri1552
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article CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
Xuguang Tai, Michelle Cowan, Lionel Feigenbaum and Alfred Singer Nature Immunology6, 152–162
(February 2005); doi:10.1038/ni1160
| Abstract | Full Text (HTML/PDF) |
research article Specification of motoneurons from human embryonic stem cells
Xue-Jun Li, Zhong-Wei Du, Ewa D Zarnowska, Matthew Pankratz, Lauren O Hansen, Robert A Pearce and Su-Chun Zhang Nature Biotechnology23, 215–221
(February 2005); doi:10.1038/nbt1063
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letter p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
Tongxiang Lin, Connie Chao, Shin'ichi Saito, Sharlyn J. Mazur, Maureen E. Murphy, Ettore Appella and Yang Xu Nature Cell Biology7, 165–171
(February 2005); doi:10.1038/ncb1211
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article Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
Roman Spörri and Caetano Reis e Sousa Nature Immunology6, 163–170
(February 2005); doi:10.1038/ni1162
| Abstract | Full Text (HTML/PDF) |
news and views No driving without a license
William R Heath and Jose A Villadangos Nature Immunology6, 125–126
(February 2005); doi:10.1038/ni0205-125
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January
letters to nature Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins
Alice E. Chen, David D. Ginty and Chen-Ming Fan Nature433, 317–322
(20 January 2005); doi:10.1038/nature03126
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news and views Signal transduction: A new canon
Olivier Pourquié Nature433, 208–209
(20 January 2005); doi:10.1038/433208a
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letter A critical role for Cyclin E in cell fate determination in the central nervous system of Drosophila melanogaster
Christian Berger, S. K. Pallavi, Mohit Prasad, L. S. Shashidhara and Gerhard M. Technau Nature Cell Biology7, 56–62
(January 2005); doi:10.1038/ncb1203
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news and views Cyclin E at the centre of an identity crisis
William Chia and Sergei N. Prokopenko Nature Cell Biology7, 3–5
(January 2005); doi:10.1038/ncb0105-3
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research article Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells
Marie-Catherine Giarratana, Ladan Kobari, Hélène Lapillonne, David Chalmers, Laurent Kiger, Thérèse Cynober, Michael C Marden, Henri Wajcman and Luc Douay Nature Biotechnology23, 69–74
(January 2005); doi:10.1038/nbt1047
| Abstract | Full Text (HTML/PDF) |
news and views Banking on red blood cells
Narla Mohandas Nature Biotechnology23, 35–36
(January 2005); doi:10.1038/nbt0105-35
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article Protection of p27Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation
Daniel Larocque, André Galarneau, Hsueh-Ning Liu, Michelle Scott, Guillermina Almazan and Stéphane Richard Nature Neuroscience8, 27–33
(January 2005); doi:10.1038/nn1359
| Abstract | Full Text (HTML/PDF) |
research article FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development
Mario N Chamorro, Donald R Schwartz, Alin Vonica, Ali H Brivanlou, Kathleen R Cho and Harold E Varmus EMBO Journal24, 73–84
(January 2005); doi:10.1038/sj.emboj.7600460
| Abstract | Full Text (HTML/PDF) |
review article Protein tyrosine phosphatases and the immune response
Tomas Mustelin, Torkel Vang and Nunzio Bottini Nature Reviews Immunology5, 43–57
(January 2005); doi:10.1038/nri1530
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letter Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
Sergey Apionishev, Natalya M. Katanayeva, Steven A. Marks, Daniel Kalderon and Andrew Tomlinson Nature Cell Biology7, 86–92
(January 2005); doi:10.1038/ncb1210
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review article WNT signalling and haematopoiesis: a WNT-WNT situation
Frank J.T. Staal and Hans C. Clevers Nature Reviews Immunology5, 21–30
(January 2005); doi:10.1038/nri1529
| Summary | Full Text (HTML / PDF) |
