article Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
Irene Noguera-Troise, Christopher Daly, Nicholas J. Papadopoulos, Sandra Coetzee, Pat Boland, Nicholas W. Gale, Hsin Chieh Lin, George D. Yancopoulos and Gavin Thurston Nature444, 1032–1037
(21 December 2006); doi:10.1038/nature05355
| Summary | Full Text (HTML / PDF) |
letter Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
John Ridgway, Gu Zhang, Yan Wu, Scott Stawicki, Wei-Ching Liang, Yvan Chanthery, Joe Kowalski, Ryan J. Watts, Christopher Callahan, Ian Kasman, Mallika Singh, May Chien, Christine Tan, Jo-Anne S. Hongo, Fred de Sauvage, Greg Plowman and Minhong Yan Nature444, 1083–1087
(21 December 2006); doi:10.1038/nature05313
| First Paragraph | Full Text (HTML / PDF) |
article A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Laura J. Niedernhofer, George A. Garinis, Anja Raams, Astrid S. Lalai, Andria Rasile Robinson, Esther Appeldoorn, Hanny Odijk, Roos Oostendorp, Anwaar Ahmad, Wibeke van Leeuwen, Arjan F. Theil, Wim Vermeulen, Gijsbertus T. J. van der Horst, Peter Meinecke, Wim J. Kleijer, Jan Vijg, Nicolaas G. J. Jaspers and Jan H. J. Hoeijmakers Nature444, 1038–1043
(21 December 2006); doi:10.1038/nature05456
| Summary | Full Text (HTML / PDF) |
letter Early events in the thymus affect the balance of effector and regulatory T cells
Daniel J. Pennington, Bruno Silva-Santos, Tobias Silberzahn, Mónica Escórcio-Correia, Martin J. Woodward, Scott J. Roberts, Adrian L. Smith, P. Julian Dyson and Adrian C. Hayday Nature444, 1073–1077
(21 December 2006); doi:10.1038/nature05368
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letter Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination
Lucia Di Marcotullio, Elisabetta Ferretti, Azzura Greco, Enrico De Smaele, Agnese Po, Maria Anna Sico, Maurizio Alimandi, Giuseppe Giannini, Marella Maroder, Isabella Screpanti & Alberto Gulino Nature Cell Biology8, 1415–1423
(December 2006); doi:10.1038/ncb1510
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letter Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
Kojiro Sato, Ayako Suematsu, Tomoki Nakashima, Sayaka Takemoto-Kimura, Kazuhiro Aoki, Yasuyuki Morishita, Hiroshi Asahara, Keiichi Ohya, Akira Yamaguchi, Toshiyuki Takai, Tatsuhiko Kodama, Talal A Chatila, Haruhiko Bito & Hiroshi Takayanagi Nature Medicine12, 1410–1416
(December 2006); doi:10.1038/nm1515
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letter v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation
Seoung-Hoon Lee, Jaerang Rho, Daewon Jeong, Jai-Yoon Sul, Taesoo Kim, Nacksung Kim, Ju-Seob Kang, Takeshi Miyamoto, Toshio Suda, Sun-Kyeong Lee, Robert J Pignolo, Boguslawa Koczon-Jaremko, Joseph Lorenzo & Yongwon Choi Nature Medicine12, 1403–1409
(December 2006); doi:10.1038/nm1514
| First Paragraph | Full Text (HTML / PDF) |
review How flies get their size: genetics meets physiology
Bruce A. Edgar Nature Reviews Genetics7, 907–916
(December 2006); doi:10.1038/nrg1989
| Summary | Full Text (HTML / PDF) |
news and views Of Fat flies and Hippos, or the magic of animal size
Fernando Casares, Carlos M Luque & Maria J Tavares Nature Structural & Molecular Biology 13, 1051–1053
(December 2006); doi:10.1038/nsmb1206-1051
| Summary | Full Text (HTML / PDF) |
letter The cytohesin Steppke is essential for insulin signalling in Drosophila
Bernhard Fuss, Thomas Becker, Ingo Zinke and Michael Hoch Nature444, 945–948
(14 December 2006); doi:10.1038/nature05412
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letter A Wnt-Axin2-GSK3β cascade regulates Snail1 activity in breast cancer cells
Jong In Yook, Xiao-Yan Li, Ichiro Ota, Casey Hu, Hyun Sil Kim, Nam Hee Kim, So Young Cha, Joo Kyung Ryu, Yoon Jung Choi, Jin Kim, Eric R. Fearon & Stephen J. Weiss Nature Cell Biology8, 1398–1406
(December 2006); doi:10.1038/ncb1508
| First Paragraph | Full Text (HTML / PDF) |
letter Centriole assembly in Caenorhabditis elegans
Alastair M. Hosie, Megan E. Wilkins, Helena M. A. da Silva and Trevor G. Smart Nature444, 619–623
(30 November 2006); doi:10.1038/nature05318
| First Paragraph | Full Text (HTML / PDF) |
review Adipocyte differentiation from the inside out
Evan D. Rosen and Ormond A. MacDougald Nature Reviews Molecular Cell Biology7, 885–896
(December 2006); doi:10.1038/nrm2066
| Summary | Full Text (HTML / PDF) |
article Control of thymocyte development and recombination-activating gene expression by the zinc finger protein Zfp608
Feng Zhang, Lance R Thomas, Eugene M Oltz & Thomas M Aune Nature Immunology7, 1309–1316
(December 2006); doi:10.1038/ni1397
| Summary | Full Text (HTML / PDF) |
news and views Fetal thymocyte development: putting a zinc finger on it?
Andrea C Carpenter & Craig H Bassing Nature Immunology7, 1285–1286
(December 2006); doi:10.1038/ni1206-1285
| Summary | Full Text (HTML / PDF) |
article SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS
Ya Dai, Hidenori Taru, Scott L Deken, Brock Grill, Brian Ackley, Michael L Nonet & Yishi Jin Nature Neuroscience9, 1479–1487
(December 2006); doi:10.1038/nn1808
| Summary | Full Text (HTML / PDF) |
letter BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
Kunikazu Tsuji, Amitabha Bandyopadhyay, Brian D Harfe, Karen Cox, Sanjeev Kakar, Louis Gerstenfeld, Thomas Einhorn, Clifford J Tabin & Vicki Rosen Nature Genetics38, 1424–1429
(December 2006); doi:10.1038/ng1916
| First Paragraph | Full Text (HTML / PDF) |
November
letter Self-incompatibility in Papaver targets soluble inorganic pyrophosphatases in pollen
Barend H. J. de Graaf, Jason J. Rudd, Michael J. Wheeler, Ruth M. Perry, Elizabeth M. Bell, Kim Osman, F. Christopher H. Franklin and Vernonica E. Franklin-Tong Nature444, 490–493
(23 November 2006); doi:10.1038/nature05311
| First Paragraph | Full Text (HTML / PDF) |
review Auxin in action: signalling, transport and the control of plant growth and development
William D. Teale, Ivan A. Paponov and Klaus Palme Nature Reviews Molecular Cell Biology7, 847–859
(November 2006); doi:10.1038/nrm2020
| Summary | Full Text (HTML / PDF) |
article Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
Neeta S Roy, Carine Cleren, Shashi K Singh, Lichuan Yang, M Flint Beal & Steven A Goldman Nature Medicine12, 1259–1268
(November 2006); doi:10.1038/nm1495
| Summary | Full Text (HTML / PDF) |
brief communication DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis
Bettina Lorenz-Depiereux, Murat Bastepe, Anna Benet-Pagès, Mustapha Amyere, Janine Wagenstaller, Ursula Müller-Barth, Klaus Badenhoop, Stephanie M Kaiser, Roger S Rittmaster, Alan H Shlossberg, José L Olivares, César Loris, Feliciano J Ramos, Francis Glorieux, Miikka Vikkula, Harald Jüppner & Tim M Strom Nature Genetics38, 1248–1250
(November 2006); doi:10.1038/ng1868
| Summary | Full Text (HTML / PDF) |
news and views Bone talk
Susan C Schiavi Nature Genetics38, 1230–1231
(November 2006); doi:10.1038/ng1106-1230
| Summary | Full Text (HTML / PDF) |
A protein interaction network for pluripotency of embryonic stem cells
Jianlong Wang, Sridhar Rao, Jianlin Chu, Xiaohua Shen, Dana N. Levasseur, Thorold W. Theunissen and Stuart H. Orkin Nature444, 364–368
(16 November 2006); doi:10.1038/nature05284
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letter Boc is a receptor for sonic hedgehog in the guidance of commissural axons
Ami Okada , Frédéric Charron , Steves Morin, David S. Shin, Karen Wong, Pierre J. Fabre, Marc Tessier-Lavigne and Susan K. McConnell Nature444, 369–373
(16 November 2006); doi:10.1038/nature05246
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letter Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence
Akiko Takahashi, Naoko Ohtani, Kimi Yamakoshi, Shin-ichi Iida, Hidetoshi Tahara, Keiko Nakayama, Keiichi I. Nakayama, Toshinori Ide, Hideyuki Saya & Eiji Hara Nature Cell Biology8, 1291–1297
(November 2006); doi:10.1038/ncb1491
| First Paragraph | Full Text (HTML / PDF) |
news and views ROS as a tumour suppressor?
Matthew R. Ramsey & Norman E. Sharpless Nature Cell Biology8, 1213–1215
(November 2006); doi:10.1038/ncb1106-1213
| Summary | Full Text (HTML / PDF) |
article RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
Yi Gu, Hee-Don Chae, Jamie E Siefring, Aparna C Jasti, David A Hildeman & David A Williams Nature Immunology7, 1182–1190
(November 2006); doi:10.1038/ni1396
| Summary | Full Text (HTML / PDF) |
letter R-spondin1 is essential in sex determination, skin differentiation and malignancy
Pietro Parma, Orietta Radi, Valerie Vidal, Marie Christine Chaboissier, Elena Dellambra, Stella Valentini, Liliana Guerra, Andreas Schedl & Giovanna Camerino Nature Genetics38, 1304–1309
(November 2006); doi:10.1038/ng1907
| First Paragraph | Full Text (HTML / PDF) |
brief communication The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
Diana C Blaydon, Yoshiyuki Ishii, Edel A O'Toole, Harriet C Unsworth, Muy-Teck Teh, Franz Rüschendorf, Claire Sinclair, Väinö K Hopsu-Havu, Nicholas Tidman, Celia Moss, Rosemarie Watson, David de Berker, Muhammad Wajid, Angela M Christiano & David P Kelsell Nature Genetics38, 1245–1247
(November 2006); doi:10.1038/ng1883
| Summary | Full Text (HTML / PDF) |
news and views R-spondin1 tips the balance in sex determination
Blanche Capel Nature Genetics38, 1233–1234
(November 2006); doi:10.1038/ng1106-1233
| Summary | Full Text (HTML / PDF) |
review Orchestrating ontogenesis: variations on a theme by sonic hedgehog
Philip W. Ingham and Marysia Placzek Nature Reviews Genetics7, 841–850
(November 2006); doi:10.1038/nrg1969
| Summary | Full Text (HTML / PDF) |
review Reelin, lipoprotein receptors and synaptic plasticity
Joachim Herz and Ying Chen Nature Reviews Neuroscience7, 850–859
(November 2006); doi:10.1038/nrn2009
| Summary | Full Text (HTML / PDF) |
review Regulation of cell fate in the sensory epithelia of the inner ear
Matthew W. Kelley Nature Reviews Neuroscience7, 837–849
(November 2006); doi:10.1038/nrn1987
| Summary | Full Text (HTML / PDF) |
article BMP-4 is required for hepatic specification of mouse embryonic stem cell-derived definitive endoderm
Valerie Gouon-Evans, Lise Boussemart, Paul Gadue, Dirk Nierhoff, Christoph I Koehler, Atsushi Kubo, David A Shafritz & Gordon Keller Nature Biotechnology24, 1402–1411
(November 2006); doi:10.1038/nbt1258
| Summary | Full Text (HTML / PDF) |
review Polycomb silencers control cell fate, development and cancer
Anke Sparmann and Maarten van Lohuizen Nature Reviews Cancer6, 846–856
(November 2006); doi:10.1038/nrc1991
| Summary | Full Text (HTML / PDF) |
article Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch
Rebecca J Richardson, Jill Dixon, Saimon Malhotra, Matthew J Hardman, Lynnette Knowles, Ray P Boot-Handford, Paul Shore, Alan Whitmarsh & Michael J Dixon Nature Genetics38, 1329–1334
(November 2006); doi:10.1038/ng1894
| Summary | Full Text (HTML / PDF) |
article The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia
Diana C Blaydon, Yoshiyuki Ishii, Edel A O'Toole, Harriet C Unsworth, Muy-Teck Teh, Franz Rüschendorf, Claire Sinclair, Väinö K Hopsu-Havu, Nicholas Tidman, Celia Moss, Rosemarie Watson, David de Berker, Muhammad Wajid, Angela M Christiano & David P Kelsell Nature Genetics12, 1301–1309
(November 2006); doi:10.1038/ng1883
| Summary | Full Text (HTML / PDF) |
letter Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya
Isao Oishi, Yasuhiko Kawakami, Ángel Raya, Carles Callol-Massot & Juan Carlos Izpisúa Belmonte Nature Genetics38, 1316–1322
(November 2006); doi:10.1038/ng1892
| First Paragraph | Full Text (HTML / PDF) |
October
article Insights into social insects from the genome of the honeybee Apis mellifera
The Honeybee Genome Sequencing Consortium et al. Nature443, 931–949
(26 October 2006); doi:10.1038/nature05260
| Summary | Full Text (HTML / PDF) |
news and views Genomics: How to make a social insect
Edward O. Wilson Nature443, 919–920
(26 October 2006); doi:10.1038/443919a
| Full Text (HTML / PDF) |
letter Regulatory constraints in the evolution of the tetrapod limb anterior-posterior polarity
Basile Tarchini, Denis Duboule and Marie Kmita Nature443, 985–988
(26 October 2006); doi:10.1038/nature05247
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review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology6, 728–740
(October 2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
article Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones
Karen Y Wu, Jonathan H Zippin, David R Huron, Margarita Kamenetsky, Ulrich Hengst, Jochen Buck, Lonny R Levin & Samie R Jaffrey Nature Neuroscience9, 1257–1264
(September 2006); doi:10.1038/nn1767
| Summary | Full Text (HTML / PDF) |
review Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development
Marc Fuccillo, Alexandra L. Joyner and Gord Fishell Nature Reviews Neuroscience9, 772–783
(September 2006); doi:10.1038/nrn1990
| Summary | Full Text (HTML / PDF) |
article The Mg-chelatase H subunit is an abscisic acid receptor
Yuan-Yue Shen, Xiao-Fang Wang, Fu-Qing Wu, Shu-Yuan Du, Zheng Cao, Yi Shang, Xiu-Ling Wang, Chang-Cao Peng, Xiang-Chun Yu, Sai-Yong Zhu, Ren-Chun Fan, Yan-Hong Xu and Da-Peng Zhang Nature443, 823–826
(19 October 2006); doi:10.1038/nature05176
| Summary | Full Text (HTML / PDF) |
letter Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1
Jinqiu Zhang, Wai-Leong Tam, Guo Qing Tong, Qiang Wu, Hsiao-Yun Chan, Boon-Seng Soh, Yuefei Lou, Jianchang Yang, Yupo Ma, Li Chai, Huck-Hui Ng, Thomas Lufkin, Paul Robson & Bing Lim Nature Cell Biology8, 1114–1123
(2006); doi:10.1038/ncb1481
| Summary | Full Text (HTML / PDF) |
article Surface-bound chemokines capture and prime T cells for synapse formation
Rachel S Friedman, Jordan Jacobelli & Matthew F Krummel Nature Immunology7, 1101–1108
(2006); doi:10.1038/ni1384
| Summary | Full Text (HTML / PDF) |
article Decidual NK cells regulate key developmental processes at the human fetal-maternal interface
Jacob Hanna, Debra Goldman-Wohl, Yaron Hamani, Inbal Avraham, Caryn Greenfield, Shira Natanson-Yaron, Diana Prus, Leonor Cohen-Daniel, Tal I Arnon, Irit Manaster, Roi Gazit, Vladimir Yutkin, Daniel Benharroch, Angel Porgador, Eli Keshet, Simcha Yagel & Ofer Mandelboim Nature Medicine12, 1065–1074
( 2006); doi:10.1038/nm1452
| Summary | Full Text (HTML / PDF) |
news and views Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays
Meghana M Kulkarni, Matthew Booker, Serena J Silver, Adam Friedman, Pengyu Hong, Norbert Perrimon & Bernard Mathey-Prevot Nature Methods3, 833–838
(2006); doi:10.1038/nmeth935
| Summary | Full Text (HTML / PDF) |
article Role of Bax and Bak in mitochondrial morphogenesis
Mariusz Karbowski, Kristi L. Norris, Megan M. Cleland, Seon-Yong Jeong and Richard J. Youle Nature443, 658–662
(12 October 2006); doi:10.1038/nature05111
| Summary | Full Text (HTML / PDF) |
review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology7, 728–740
(2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
brief communication Local caspase activity directs engulfment of dendrites during pruning
Darren W Williams, Shu Kondo, Agnieszka Krzyzanowska, Yasushi Hiromi & James W Truman Nature Neuroscience9, 1234–1236
(2006); doi:10.1038/nn1774
| Summary | Full Text (HTML / PDF) |
September
letter Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos
Fumio Motegi & Asako Sugimoto Nature Cell Biology8, 978–985
(September 2006); doi:10.1038/ncb1459
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article The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface
Silvia Cappello, Alessio Attardo, Xunwei Wu, Takuji Iwasato, Shigeyoshi Itohara, Michaela Wilsch-Bräuninger, Hanna M Eilken, Michael A Rieger, Timm T Schroeder, Wieland B Huttner, Cord Brakebusch & Magdalena Götz Nature Neuroscience9, 1099–1107
(September 2006); doi:10.1038/nn1744
| Summary | Full Text (HTML / PDF) |
letter A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula
Kevin M. Vogeli, Suk-Won Jin, Gail R. Martin and Didier Y. R. Stainier Nature443, 337–339
(21 September 2006); doi:10.1038/nature05045
| Summary | Full Text (HTML / PDF) |
review Notch signalling: a simple pathway becomes complex
Sarah J. Bray Nature Reviews Molecular Cell Biology7, 678–689
(September 2006); doi:10.1038/nrm2009
| Summary |
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letter Soma-germline interactions coordinate homeostasis and growth in the Drosophila gonad
Lilach Gilboa and Ruth Lehmann Nature443, 97–100
(7 September 2006); doi:10.1038/nature05068
| Summary | Full Text (HTML / PDF) |
article Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
Marcel Batten, Ji Li, Sothy Yi, Noelyn M Kljavin, Dimitry M Danilenko, Sophie Lucas, James Lee, Frederic J de Sauvage & Nico Ghilardi Nature Immunology7, 929–936
(13 August 2006); doi:10.1038/ni1375
| Summary | Full Text (HTML / PDF) |
article Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Jason S Stumhofer, Arian Laurence, Emma H Wilson, Elaine Huang, Cristina M Tato, Leanne M Johnson, Alejandro V Villarino, Qiulong Huang, Akihiko Yoshimura, David Sehy, Christiaan J M Saris, John J O'Shea, Lothar Hennighausen, Matthias Ernst & Christopher A Hunter Nature Immunology7, 937–945
(13 August 2006); doi:10.1038/ni1376
| Summary | Full Text (HTML / PDF) |
news and views All in the family: IL-27 suppression of TH-17 cells
John Colgan & Paul Rothmanr Nature Immunology7, 899–901
(2006); doi:10.1038/ni0906-899
| Summary | Full Text (HTML / PDF) |
August
article Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness
Jolanta M Topczewska, Lynne-Marie Postovit, Naira V Margaryan, Anthony Sam, Angela R Hess, William W Wheaton, Brian J Nickoloff, Jacek Topczewski & Mary J C Hendrix Nature Medicine12, 925–932
(10 August 2006); doi:10.1038/nm1448
| Summary | Full Text (HTML / PDF) |
letter NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus
Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage Nature442, 929–933
(24 August 2006); doi:10.1038/nature05028
| First Paragraph | Full Text (HTML / PDF) |
news and views Embryogenesis meets tumorigenesis
John T Lee & Meenhard Herlyn Nature Medicine12, 882–884
(10 August 2006); doi:10.1038/nm0806-882
| Summary | Full Text (HTML / PDF) |
letter Mesodermal Wnt2b signalling positively regulates liver specification
Elke A. Ober, Heather Verkade, Holly A. Field and Didier Y. R. Stainier Nature442, 688–691
(10 August 2006); doi:10.1038/nature04888
| First Paragraph | Full Text (HTML / PDF) |
July
letter Endothelial tubes assemble from intracellular vacuoles in vivo
Makoto Kamei, W. Brian Saunders, Kayla J. Bayless, Louis Dye, George E. Davis and Brant M. Weinstein Nature442, 453–456
(27 July 2006); doi:10.1038/nature04923
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news and views Developmental biology: The hole picture
Keith Mostov and Fernando Martin-Belmonte Nature442, 363–364
(27 July 2006); doi:10.1038/442363a
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article Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases
Anouk Caraux, Qingxian Lu, Nadine Fernandez, Sylvain Riou, James P Di Santo, David H Raulet, Greg Lemke & Claude Roth Nature Immunology7, 747–754
(June 2006); doi:10.1038/ni1353
| Summary | Full Text (HTML / PDF) |
news and views NK cell development: Gas matters
Thierry Walzer & Eric Vivier Nature Immunology7, 702–704
(July 2006); doi:10.1038/ni0706-702
| Summary | Full Text (HTML / PDF) |
article VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis
Betty Y Y Tam, Kevin Wei, John S Rudge, Jana Hoffman, Joceyln Holash, Sang-ki Park, Jenny Yuan, Colleen Hefner, Cecile Chartier, Jeng-Shin Lee, Shelly Jiang, Nihar R Niyak, Frans A Kuypers, Lisa Ma, Uma Sundram, Grace Wu, Joseph A Garcia, Stanley L Schrier, Jacquelyn J Maher, Randall S Johnson, George D Yancopoulos, Richard C Mulligan & Calvin J Kuo Nature Medicine7, 793–800
(July 2006); doi:10.1038/nm1428
| Summary | Full Text (HTML / PDF) |
news and views VEGF inhibitors make blood
Christian Fischer, Peter Carmeliet & Edward M Conway Nature Medicine7, 732–734
(July 2006); doi:10.1038/nm0706-732
| Summary | Full Text (HTML / PDF) |
June
article Midline radial glia translocation and corpus callosum formation require FGF signaling
Karen Müller Smith, Yasushi Ohkubo, Maria Elisabetta Maragnoli, Mladen-Roko Ras caronin, Michael L Schwartz, Nenad S caronestan & Flora M Vaccarino Nature Neuroscience9, 787 - 797
(June 2006); doi:10.1038/nn1705
| Summary | Full Text (HTML / PDF) |
letter Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells
Patricia M. White, Angelika Doetzlhofer, Yun Shain Lee, Andrew K. Groves and Neil Segil Nature441, 984–987
(22 June 2006); doi:10.1038/nature04849
| First Paragraph | Full Text (HTML / PDF) |
letter Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
Simona W. Rossi, William E. Jenkinson, Graham Anderson and Eric J. Jenkinson Nature441, 988–991
(22 June 2006); doi:10.1038/nature04813
| First Paragraph | Full Text (HTML / PDF) |
article Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism
Valérie Senée, Claude Chelala, Sabine Duchatelet, Daorong Feng, Hervé Blanc, Jack-Christophe Cossec, Céline Charon, Marc Nicolino, Pascal Boileau, Douglas R Cavener, Pierre Bougnères, Doris Taha & Cécile Julier Nature Genetics38, 682 - 687
(June 2006); doi:10.1038/ng1802
| Summary | Full Text (HTML / PDF) |
article Noise-resistant and synchronized oscillation of the segmentation clock
Kazuki Horikawa, Kana Ishimatsu, Eiichi Yoshimoto, Shigeru Kondo and Hiroyuki Takeda Nature441, 719–723
(08 June 2006); doi:10.1038/nature04861
| Summary | Full Text (HTML / PDF) |
letter Social interactions among epithelial cells during tracheal branching morphogenesis
Amin S. Ghabrial and Mark A. Krasnow Nature441, 746–749
(08 June 2006); doi:10.1038/nature04829
| First Paragraph | Full Text (HTML / PDF) |
article NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
Joseph R. Arron, Monte M. Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R. Neilson, Lei Chen, Jeremy J. Heit, Seung K. Kim, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Uta Francke, Isabella A. Graef and Gerald R. Crabtree Nature441, 595–600
(01 June 2006); doi:10.1038/nature04678
| Summary | Full Text (HTML / PDF) |
letter A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
Yousang Gwack, Sonia Sharma, Julie Nardone, Bogdan Tanasa, Alina Iuga, Sonal Srikanth, Heidi Okamura, Diana Bolton, Stefan Feske, Patrick G. Hogan and Anjana Rao Nature441, 646–650
(01 June 2006); doi:10.1038/nature04631
| First Paragraph | Full Text (HTML / PDF) |
letter Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells
Katia Ancelin, Ulrike C. Lange, Petra Hajkova, Robert Schneider, Andrew J. Bannister, Tony Kouzarides & M. Azim Surani
Published online: 14 May 2006
doi:10.1038/ncb1413
| First Paragraph | Full Text (HTML / PDF) |
May
letter Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos
Rosana Muñoz, Mauricio Moreno, Carlos Oliva, Claudio Orbenes & Juan Larraín Nature Cell Biology8, 492–500
(May 2006); doi:10.1038/ncb1399
| Summary | Full Text (HTML / PDF) |
letter Polycomb complexes repress developmental regulators in murine embryonic stem cells
Laurie A. Boyer, Kathrin Plath , Julia Zeitlinger, Tobias Brambrink, Lea A. Medeiros, Tong Ihn Lee, Stuart S. Levine, Marius Wernig, Adriana Tajonar, Mridula K. Ray, George W. Bell, Arie P. Otte, Miguel Vidal, David K. Gifford, Richard A. Young and Rudolf Jaenisch Nature441, 349–353
(18 May 2006); doi:10.1038/nature04733
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letter Specification of the neural crest occurs during gastrulation and requires Pax7
Martín L. Basch, Marianne Bronner–Fraser and Martín I. García–Castro Nature441, 218–222
(11 May 2006); doi:10.1038/nature04684
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letter Transforming growth factor–ß induces development of the TH17 lineage
Paul R. Mangan, Laurie E. Harrington, Darrell B. O'Quinn, Whitney S. Helms, Daniel C. Bullard, Charles O. Elson, Robin D. Hatton, Sharon M. Wahl, Trenton R. Schoeb and Casey T. Weaver Nature441, 231–234
(11 May 2006); doi:10.1038/nature04754
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letter Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Estelle Bettelli, Yijun Carrier, Wenda Gao, Thomas Korn, Terry B. Strom, Mohamed Oukka, Howard L. Weiner and Vijay K. Kuchroo Nature441, 235–238
(11 May 2006); doi:10.1038/nature04753
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news and views Immunology: What does it mean to be just 17?
Cristina M. Tato and John J. O'Shea Nature441, 166–168
(11 May 2006); doi:10.1038/441166a
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review article Mesoderm induction: from caps to chips
David Kimelman Nature Reviews Genetics7, 360–372
(May 2006); doi:10.1038/nrg1837
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April
article The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
Stephane Angers, Chris J. Thorpe, Travis L. Biechele, Seth J. Goldenberg, Ning Zheng, Michael J. MacCoss & Randall T. Moon Nature Cell Biology8, 348–357
(April 2006); doi:10.1038/ncb1381 First Paragraph | Full Text (HTML / PDF) |
article Early hematopoietic lineage restrictions directed by Ikaros
Toshimi Yoshida, Samuel Yao-Ming Ng, Juan Carlos Zuniga-Pflucker & Katia Georgopoulos Nature Immunology7, 382–391
(April 2006); doi:10.1038/ni1314
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news and views Hematopoiesis flies high with Ikaros
Stephen T Smale & Kenneth Dorshkind Nature Immunology7, 367–369
(April 2006); doi:10.1038/ni0406-367
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review article Left-right asymmetry in the vertebrate embryo: from early information to higher-level integration
Ángel Raya and Juan Carlos Izpisúa Belmonte Nature Reviews Genetics7, 283–293
(April 2006); doi:10.1038/nrg1830
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article Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin protein
Osamu Muraoka, Takashi Shimizu, Taijiro Yabe, Hideaki Nojima, Young-Ki Bae, Hisashi Hashimoto & Masahiko Hibi Nature Cell Biology8, 329–340
(2006); doi:10.1038/ncb1379
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March
article Silencing of EphA3 through a cis interaction with ephrinA5
Ricardo F Carvalho, Martin Beutler, Katharine J M Marler, Bernd Knöll, Elena Becker-Barroso, R Heintzmann, Tony Ng & Uwe Drescher Nature Neuroscience9, 322–330
(March 2006); doi:10.1038/nn1655
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letter The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation
Irina Naguibneva, Maya Ameyar-Zazoua, Anna Polesskaya, Slimane Ait-Si-Ali, Reguina Groisman, Mouloud Souidi, Sylvain Cuvellier & Annick Harel-Bellan Nature Cell Biology8, 278–284
(30 March 2006); doi:10.1038/ncb1373
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letter An excitable gene regulatory circuit induces transient cellular differentiation
Gürol M. Süel, Jordi Garcia-Ojalvo, Louisa M. Liberman and Michael B. Elowitz Nature440, 545–550
(23 March 2006); doi:10.1038/nature04588
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letter Retinoic-acid signalling in node ectoderm and posterior neural plate directs left-right patterning of somitic mesoderm
Ioan Ovidiu Sirbu and Gregg Duester Nature Cell Biology8, 271–277
(March 2006); doi:10.1038/ncb1374
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article Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
Tae Joo Park, Saori L Haigo and John B Wallingford Nature Genetics38, 303–311
(March 2006); doi:10.1038/ng1753
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news and views Hedgehogs on the road to polarity
Philip L Beales Nature Genetics38, 277–279
(March 2006); doi:10.1038/ng0306-277
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February
letter The Polycomb group protein EZH2 directly controls DNA methylation
Emmanuelle Viré, Carmen Brenner, Rachel Deplus, Loïc Blanchon, Mario Fraga, Céline Didelot, Lluis Morey, Aleyde Van Eynde, David Bernard, Jean-Marie Vanderwinden, Mathieu Bollen, Manel Esteller, Luciano Di Croce, Yvan de Launoit and François Fuks Nature439, 871–874
(16 February 2006); doi:10.1038/nature04431
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news and views Developmental biology: Two paths to silence merge
Panthea Taghavi and Maarten van Lohuizen Nature439, 794–795
(16 February 2006); doi:10.1038/439794a
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letter The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
Jian-Fu Chen, Elizabeth M Mandel, J Michael Thomson, Qiulian Wu, Thomas E Callis, Scott M Hammond, Frank L Conlon and Da-Zhi Wang Nature Genetics38, 228–233
(February 2006); doi:10.1038/ng1725
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review article Developmental apoptosis in C. elegans: a complex CEDnario
Guillaume Lettre and Michael O. Hengartner Nature Reviews Molecular Cell Biology7, 97–108
(February 2006); doi:10.1038/nrm1836
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article Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens
Julie Bakker, Christelle De Mees, Quentin Douhard, Jacques Balthazart, Philippe Gabant, Josiane Szpirer and Claude Szpirer Nature Neuroscience9, 220–226
(February 2006); doi:10.1038/nn1624
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news and views Defending the brain from estrogen
David A Puts, Cynthia L Jordan and S Marc Breedlove Nature Neuroscience9, 155–156
(February 2006); doi:10.1038/nn0206-155
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review article Notch signalling in vertebrate neural development
Angeliki Louvi and Spyros Artavanis-Tsakonas Nature Reviews Neuroscience7, 93–102
(February 2006); doi:10.1038/nrn1847
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article Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart
Kazuko Koshiba-Takeuchi, Jun K Takeuchi, Eric P Arruda, Irfan S Kathiriya, Rong Mo, Chi-chung Hui, Deepak Srivastava and Benoit G Bruneau Nature Genetics38, 175–183
(February 2006); doi:10.1038/ng1707
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article The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons
Frèdèric Marmigére, Andreas Montelius, Michael Wegner, Yoram Groner, Louis F Reichardt and Patrik Ernfors Nature Neuroscience9, 180–187
(February 2006); doi:10.1038/nn1631
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news and views Specifying nociceptors
Annette Markus Nature Neuroscience9, 162
(February 2006); doi:10.1038/nn0206-162
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January
letter The adult Drosophila posterior midgut is maintained by pluripotent stem cells
Benjamin Ohlstein and Allan Spradling Nature439, 470–474
(26 January 2006); doi:10.1038/nature04333
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letter Pregnenolone stabilizes microtubules and promotes zebrafish embryonic cell movement
Hwei-Jan Hsu, Ming-Ren Liang, Chao-Tsen Chen and Bon-chu Chung Nature439, 480–483
(26 January 2006); doi:10.1038/nature04436
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review article Developmental cell biology: Making digit patterns in the vertebrate limb
Cheryll Tickle Nature Reviews Molecular Cell Biology7, 45–53
(January 2006); doi:10.1038/nrm1830
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article A positive signal from the fertilization of the egg cell sets off endosperm proliferation in angiosperm embryogenesis
Moritz K Nowack, Paul E Grini, Marc J Jakoby, Marcel Lafos, Csaba Koncz and Arp Schnittger Nature Genetics38, 63–67
(January 2006); doi:10.1038/ng1694
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article DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system
Makoto Sato, Daiki Umetsu, Satoshi Murakami, Tetsuo Yasugi and Tetsuya Tabata Nature Neuroscience9, 67–75
(January 2006); doi:10.1038/nn1604
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letter Planar cell polarity signalling couples cell division and morphogenesis during neurulation
Brian Ciruna, Andreas Jenny, Diana Lee, Marek Mlodzik and Alexander F. Schier Nature439, 220–224
(12 January 2006); doi:10.1038/nature04375
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review article A PANorama of PAX genes in cancer and development
Ewan J. D. Robson, Shu-Jie He and Michael R. Eccles Nature Reviews Cancer6, 52–62
(January 2006); doi:10.1038/nrc1778
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review article Filtering transcriptional noise during development: concepts and mechanisms
Alfonso Martinez Arias and Penelope Hayward Nature Reviews Genetics7, 34–44
(January 2006); doi:10.1038/nrg1750
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brief communication In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes
Wigard P Kloosterman, Erno Wienholds, Ewart de Bruijn, Sakari Kauppinen and Ronald H A Plasterk Nature Methods3, 27–29
(January 2006); doi:10.1038/nmeth843
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article Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping
Adam M. Schmitt, Jun Shi, Alex M. Wolf, Chin-Chun Lu, Leslie A. King and Yimin Zou Nature439, 31–37
(05 January 2006); doi:10.1038/nature04334
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letter Dishevelled mediates ephrinB1 signalling in the eye field through the planar cell polarity pathway
Hyun-Shik Lee, Yong-Sik Bong, Kathryn B. Moore, Kathleen Soria, Sally A. Moody and Ira O. Daar Nature Cell Biology8, 55–63
(January 2006); doi:10.1038/ncb1344
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news and views Ephrins make eyes with planar cell polarity
Alexei Poliakov and David G. Wilkinson Nature Cell Biology8, 7–8
(January 2006); doi:10.1038/ncb0106-7
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