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Research library: Development/Differentiation

2009: | December | November | October | September | August | July | June | May | April | March | February | January

Other Years - Development: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008
Other Years - Differentiation: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008

letter
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells
Jean-Leon Chong et al.
Nature 462, 930–934
(17 December 2009); doi:10.1038/nature08677
| Summary | Full Text (HTML / PDF) |

letter
Modulating hedgehog signaling can attenuate the severity of osteoarthritis
Alvin C Lin et al.
Nature Medicine 15, 1421–1425
(December 2009); doi:10.1038/nm.2055
| Summary | Full Text (HTML / PDF) |

article
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
Benson C Lu et al.
Nature Genetics 41, 1295–1302
(December 2009); doi:10.1038/ng.476
| Summary | Full Text (HTML / PDF) |

review
Vertebrate limb bud development: moving towards integrative analysis of organogenesis
Rolf Zeller, Javier López-Ríos & Aimée Zuniga
Nature Reviews Genetics 10, 845–858
(December 2009); doi:10.1038/nrg2681
| Summary | Full Text (HTML / PDF) |

article
GSK-3 is a master regulator of neural progenitor homeostasis
Woo-Yang Kim et al.
Nature Neuroscience 12, 1390–1397
(November 2009); doi:10.1038/nn.2408
| Summary | Full Text (HTML / PDF) |

letter
Systems-level dynamic analyses of fate change in murine embryonic stem cells
Rong Lu et al.
Nature 462, 358–362
(19 November 2009); doi:10.1038/nature08575
| Full Text (HTML / PDF) |

article
Notch3 signaling promotes the development of pulmonary arterial hypertension
Xiaodong Li et al.
Nature Medicine 15, 1289–1297
(November 2009); doi:10.1038/nm.2021
| Summary | Full Text (HTML / PDF) |

article
Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors
Eve Seuntjens et al.
Nature Neuroscience 12, 1373–1380
(November 2009); doi:10.1038/nn.2409
| Summary | Full Text (HTML / PDF) |

article
The kinase TNIK is an essential activator of Wnt target genes
Tokameh Mahmoudi et al.
The EMBO Journal 28, 3329–3340
(November 2009); doi:10.1038/emboj.2009.285
| Summary | Full Text (HTML / PDF) |

letter
Epigenetic reversion of post-implantation epiblast to pluripotent embryonic stem cells
Siqin Bao et al.
Nature 461, 1292–1295
(29 October 2009); doi:10.1038/nature08534
| Full Text (HTML / PDF) |

article
C/EBPα and β couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation
Rodolphe G. Lopez et al.
Nature Cell Biology 11, 1181–1190
(October 2009); doi:10.1038/ncb1960
| Summary | Full Text (HTML / PDF) |

article
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
Duncan M Gascoyne et al.
Nature Immunology 10, 1118–1124
(October 2009); doi:10.1038/ni.1787
| Summary | Full Text (HTML / PDF) |

news and views
A defining factor for natural killer cell development
James P Di Santo
Nature Immunology 10, 1051–1052
(October 2009); doi:10.1038/ni1009-1051
| Full Text (HTML / PDF) |

article
AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex
Luisa Pinto et al.
Nature Neuroscience 12, 1229–1237
(October 2009); doi:10.1038/nn.2399
| Summary | Full Text (HTML / PDF) |

news and views
Regional control of cortical lamination
Ronald R Waclaw & Kenneth Campbell
Nature Neuroscience 12, 1211–1212
(October 2009); doi:10.1038/nn1009-1211
| Full Text (HTML / PDF) |

letter
Integrin-linked kinase is an adaptor with essential functions during mouse development
Anika Lange et al.
Nature 461, 1002–1006
(15 October 2009); doi:10.1038/nature08468
| Full Text (HTML / PDF) |

letter
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development
Ryan S. Gray et al.
Nature Cell Biology 11, 1225–1232
(October 2009); doi:10.1038/ncb1966
| Summary | Full Text (HTML / PDF) |

article
Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling
Anne-Marie Martinez et al.
Nature Genetics 41, 1076–1082
(October 2009); doi:10.1038/ng.414
| Summary | Full Text (HTML / PDF) |

letter
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
Edward Owusu-Ansah & Utpal Banerjee
Nature 461, 537–541
(24 September 2009); doi:10.1038/nature08313
| Full Text (HTML / PDF) |

news and views
Developmental biology: A bad boy comes good
Ulrich Theopold
Nature 461, 486–487
(24 September 2009); doi:10.1038/461486a
| Full Text (HTML / PDF) |

article
Impaired Wnt—β-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy
Madeline A Lancaster et al.
Nature Medicine 15, 1046–1054
(September 2009); doi:10.1038/nm.2010
| Summary | Full Text (HTML / PDF) |

article
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
Tomoko Kuwabara et al.
Nature Neuroscience 12, 1097–1105
(September 2009); doi:10.1038/nn.2360
| Summary | Full Text (HTML / PDF) |

brief communication
Neurod1 is essential for the survival and maturation of adult-born neurons
Zhengliang Gao et al.
Nature Neuroscience 12, 1090–1092
(September 2009); doi:10.1038/nn.2385
| Summary | Full Text (HTML / PDF) |

news and views
Wnts blow on NeuroD1 to promote adult neuron production and diversity
Pierre Vanderhaeghen
Nature Neuroscience 12, 1079–1081
(September 2009); doi:10.1038/nn0909-1079
| Full Text (HTML / PDF) |

letter
Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-like
Hyunju Ro & Igor B. Dawid
Nature Cell Biology 11, 1121–1127
(September 2009); doi:10.1038/ncb1926
| Summary | Full Text (HTML / PDF) |

article
T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ
Qing Yu et al.
Nature Immunology 10, 992–999
(September 2009); doi:10.1038/ni.1762
| Summary | Full Text (HTML / PDF) |

progress
WNTs tune up the neuromuscular junction
Ceren Korkut & Vivian Budnik
Nature Reviews Neuroscience 10, 627–634
(September 2009); doi:10.1038/nrn2681
| Summary | Full Text (HTML / PDF) |

letter
Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex
Shingo Kajimura et al.
Nature 460, 1154–1158
(27 August 2009); doi:10.1038/nature08262
| Full Text (HTML / PDF) |

letter
A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
Theresa Vincent et al.
Nature Cell Biology 11, 943–950
(August 2009); doi:10.1038/ncb1905
| Summary | Full Text (HTML / PDF) |

perspective
Crosstalk of Notch with p53 and p63 in cancer growth control
G. Paolo Dotto
Nature Reviews Cancer 9, 587–595
(August 2009); doi:10.1038/nrc2675
| Summary | Full Text (HTML / PDF) |

letter
A role for Lin28 in primordial germ-cell development and germ-cell malignancy
Jason A. West et al.
Nature 460, 909–913
(13 August 2009); doi:10.1038/nature08210
| Full Text (HTML / PDF) |

letter
A regulatory pathway involving Notch1/β-catenin/Isl1 determines cardiac progenitor cell fate
Chulan Kwon et al.
Nature Cell Biology 11, 951–957
(2009); doi:10.1038/ncb1906
| Summary | Full Text (HTML / PDF) |

article
A trophic role for Wnt-Ror kinase signaling during developmental pruning in Caenorhabditis elegans
Yu Hayashi et al.
Nature Neuroscience 12, 981–987
(August 2009); doi:10.1038/nn.2347
| Summary | Full Text (HTML / PDF) |

article
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity
Kimberly R. Cordes et al.
Nature 460, 705–710
(August 2009); doi:10.1038/nature08195
| Full Text (HTML / PDF) |

letter
Switch in FGF signalling initiates glial differentiation in the Drosophila eye
Sigrídur Rut Franzdóttir et al.
Nature 460, 758–761
(August 2009); doi:10.1038/nature08167
| Full Text (HTML / PDF) |

letter
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
Andrew S. Yoo, Brett T. Staahl, Lei Chen & Gerald R. Crabtree
Nature 460, 642–646
(30 July 2009); doi:10.1038/nature08139
| Full Text (HTML / PDF) |

letter
Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells
Luca Gattinoni et al.
Nature Medicine 15, 808–813
(July 2009); doi:10.1038/nm.1982
| Summary | Full Text (HTML / PDF) |

news and views
Tumor immunotherapy: making an immortal army
Brent H. Koehn & Stephen P. Schoenberger
Nature Medicine 15, 731–732
(July 2009); doi:10.1038/nm0709-731
| Full Text (HTML / PDF) |

review
Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo
Magdalena Zernicka-Goetz, Samantha A. Morris & Alexander W. Bruce
Nature Reviews Genetics 10, 467–477
(July 2009); doi:10.1038/nrg2564
| Summary | Full Text (HTML / PDF) |

article
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity
Ashwin Woodhoo et al.
Nature Neuroscience 12, 839–847
(July 2009); doi:10.1038/nn.2323
| Summary | Full Text (HTML / PDF) |

letter
The AP-1 transcription factor Batf controls TH17 differentiation
Barbara U. Schraml et al.
Nature 460, 405–409
(16 July 2009); doi:10.1038/nature08114
| Full Text (HTML / PDF) |

review
Proximal events in Wnt signal transduction
Stephane Angers & Randall T. Moon
Nature Reviews Molecular Cell Biology 10, 468–477
(July 2009); doi:10.1038/nrm2717
| Summary | Full Text (HTML / PDF) |

article
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction
Feng Ye et al.
Nature Neuroscience 12, 829–838
(July 2009); doi:10.1038/nn.2333
| Summary | Full Text (HTML / PDF) |

news and views
Genetics meets epigenetics: HDACs and Wnt signaling in myelin development and regeneration
Huiliang Li & William D Richardson
Nature Neuroscience 12, 815–817
(July 2009); doi:10.1038/nn0709-815
| Full Text (HTML / PDF) |

article
Telomerase modulates Wnt signalling by association with target gene chromatin
Jae-Il Park et al.
Nature 460, 66–72
(02 July 2009); doi:10.1038/nature08137
| Full Text (HTML / PDF) |

news and views
Cell biology: The not-so-odd couple
Sarah E. Millar
Nature 460, 44–45
(02 July 2009); doi:10.1038/460044a
| Full Text (HTML / PDF) |

letter
A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells
Hitoshi Niwa, Kazuya Ogawa, Daisuke Shimosato & Kenjiro Adachi
Nature 460, 118–122
(02 July 2009); doi:10.1038/nature08113
| Full Text (HTML / PDF) |

letter
Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal
Mirko H.H. Schmidt et al.
Nature Cell Biology 11, 873–880
(July 2009); doi:10.1038/ncb1896
| Summary | Full Text (HTML / PDF) |

article
Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis
Courtney M Karner et al.
Nature Genetics 41, 793–799
(July 2009); doi:10.1038/ng.400
| Summary | Full Text (HTML / PDF) |

letter
TGF-β signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3
Anjali Shukla et al.
Nature Cell Biology 11, 777–784
(June 2009); doi:10.1038/ncb1885
| Summary | Full Text (HTML / PDF) |

article
Development of immunoglobulin λ-chain–positive B cells, but not editing of immunoglobulin κ-chain, depends on NF-κB signals
Emmanuel Derudder et al.
Nature Immunology 10, 647–654
(June 2009); doi:10.1038/ni.1732
| Summary | Full Text (HTML / PDF) |

article
Live-imaging of single stem cells within their niche reveals that a U3snoRNP component segregates asymmetrically and is required for self-renewal in Drosophila
Pierre Fichelson et al.
Nature Cell Biology 11, 685–693
(June 2009); doi:10.1038/ncb1874
| Summary | Full Text (HTML / PDF) |

news and views
Wicked views on stem cell news
Ralph A. Neumüller & Juergen A. Knoblich
Nature Cell Biology 11, 678–679
(June 2009); doi:10.1038/ncb0609-678
| Full Text (HTML / PDF) |

article
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
Meghan A Koch et al.
Nature Immunology 10, 595–602
(June 2009); doi:10.1038/ni.1731
| Summary | Full Text (HTML / PDF) |

news and views
Hybrid Treg cells: steel frames and plastic exteriors
Michael J Barnes & Fiona Powrie
Nature Immunology 10, 563–564
(June 2009); doi:10.1038/ni0609-563
| Full Text (HTML / PDF) |

article
Prostaglandin E2–EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion
Chengcan Yao et al.
Nature Medicine 15, 633–640
(June 2009); doi:10.1038/nm.1968
| Summary | Full Text (HTML / PDF) |

letter
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
Jun K. Takeuchi & Benoit G. Bruneau
Nature 459, 708–711
(04 June 2009); doi:10.1038/nature08039
| Full Text (HTML / PDF) |

news and views
Developmental biology: The early heart remodelled
Fu-Sen Liang & Gerald R. Crabtree
Nature 459, 654–655
(04 June 2009); doi:10.1038/459654a
| Full Text (HTML / PDF) |

letter
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
Shawn C. Little & Mary C. Mullins
Nature Cell Biology 11, 637–643
(May 2009); doi:10.1038/ncb1870
| Summary | Full Text (HTML / PDF) |

brief communication
Embryonic stem cell–specific microRNAs promote induced pluripotency
Robert L Judson, Joshua E Babiarz, Monica Venere & Robert Blelloch
Nature Biotechnology 27, 459–461
(May 2009); doi:10.1038/nbt.1535
| Summary | Full Text (HTML / PDF) |

article
A surface transporter family conveys the trypanosome differentiation signal
Samuel Dean, Rosa Marchetti, Kiaran Kirk & Keith R. Matthews
Nature 459, 213–217
(14 May 2009); doi:10.1038/nature07997
| Full Text (HTML / PDF) |

letter
Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
Nature 459, 262–265
(14 May 2009); doi:10.1038/nature07935
| Full Text (HTML / PDF) |

letter
Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis
Christopher W. Wilson et al.
Nature 459, 98–102
(07 May 2009); doi:10.1038/nature07883
| Full Text (HTML / PDF) |

letter
A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range
Bo Gao et al.
Nature 458, 1196–1200
(30 April 2009); doi:10.1038/nature07862
| Summary | Full Text (HTML / PDF) |

article
Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi
Jennifer L. Mummery-Widmer et al.
Nature 458, 987–992
(23 April 2009); doi:10.1038/nature07936
| Summary | Full Text (HTML / PDF) |

brief communication
Inhibition of Wnt signaling by Dishevelled PDZ peptides
Yingnan Zhang et al.
Nature Chemical Biology 5, 217–219
(April 2009); doi:10.1038/nchembio.152
| Summary | Full Text (HTML / PDF) |

scientific report
Regulation of human myoblast differentiation by PEBP4
Reynaldo Garcia et al.
EMBO Reports 10, 278–284
(April 2009); doi:10.1038/embor20094
| Summary | Full Text (HTML / PDF) |

letter
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
Chen Zhao et al.
Nature 458, 776–779
(09 April 2009); doi:10.1038/nature07737
| Summary | Full Text (HTML / PDF) |

news and views
Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses
Jennifer A Chan et al.
Nature Neuroscience 12, 409–417
(April 2009); doi:10.1038/nn.2287
| Summary | Full Text (HTML / PDF) |

news and views
Proteoglycans specify Sonic Hedgehog effect
Catherine Vaillant & Denis Monard
Nature Neuroscience 12, 371–372
(April 2009); doi:10.1038/nn0409-371
| Full Text (HTML / PDF) |

letter
FGF signalling during embryo development regulates cilia length in diverse epithelia
Judith M. Neugebauer, Jeffrey D. Amack, Annita G. Peterson, Brent W. Bisgrove & H. Joseph Yost
Nature 458, 651–654
(02 April 2009); doi:10.1038/nature07753
| Summary | Full Text (HTML / PDF) |

review
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak & Robert A. Weinberg
Nature Reviews Cancer 9, 265–273
(April 2009); doi:10.1038/nrc2620
| Summary | Full Text (HTML / PDF) |

article
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation
Jing-Ruey J Yeh et al.
Nature Chemical Biology 5, 236–243
(April 2009); doi:10.1038/nchembio.147
| Summary | Full Text (HTML / PDF) |

letter
Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization
Matias Simons et al.
Nature Cell Biology 11, 286–294
(March 2009); doi:10.1038/ncb1836
| Summary | Full Text (HTML / PDF) |

article
Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation
Kiyo-aki Ishii et al.
Nature Medicine 15, 259–266
(March 2009); doi:10.1038/nm.1910
| Summary | Full Text (HTML / PDF) |

article
FGF9 monomer–dimer equilibrium regulates extracellular matrix affinity and tissue diffusion
Masayo Harada et al.
Nature Genetics 41, 289–298
(March 2009); doi:10.1038/ng.316
| Summary | Full Text (HTML / PDF) |

news and views
FGF9 on the move
Douglas Spicer
Nature Genetics 41, 272–273
(March 2009); doi:10.1038/ng0309-272
| Full Text (HTML / PDF) |

article
A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
Barbara Stecca & Ariel Ruiz i Altaba
The EMBO Journal 28, 663–676
(March 2009); doi:10.1038/emboj.2009.16
| Summary | Full Text (HTML / PDF) |

letter
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
Ye Zheng et al.
Nature 458, 351–356
(19 March 2009); doi:10.1038/nature07674
| Summary | Full Text (HTML / PDF) |

article
Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke
Marie Carlén et al.
Nature Neuroscience 12, 259–267
(March 2009); doi:10.1038/nn.2268
| Summary | Full Text (HTML / PDF) |

news and views
Notch keeps ependymal cells in line
Chunmei Zhao, Hoonkyo Suh & Fred H Gage
Nature Neuroscience 12, 243–245
(March 2009); doi:10.1038/nn0309-243
| Full Text (HTML / PDF) |

letter
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M Chambers et al.
Nature Biotechnology 27, 275–280
(March 2009); doi:10.1038/nbt.1529
| Summary | Full Text (HTML / PDF) |

brief communication
A small molecule that binds Hedgehog and blocks its signaling in human cells
Benjamin Z Stanton et al.
Nature Chemical Biology 5, 154–156
(March 2009); doi:10.1038/nchembio.142
| Summary | Full Text (HTML / PDF) |

article
Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
Sandra Stehling-Sun, Jessica Dade, Stephen L Nutt, Rodney P DeKoter & Fernando D Camargo
Nature Immunology 10, 289–296
(March 2009); doi:10.1038/ni.1694
| Summary | Full Text (HTML / PDF) |

news and views
Deciding the decider: Mef2c in hematopoiesis
Rachel M Gerstein
Nature Immunology 10, 235–236
(March 2009); doi:10.1038/ni0309-235
| Full Text (HTML / PDF) |

review
RUNX proteins in transcription factor networks that regulate T-cell lineage choice
Amélie Collins, Dan R. Littman & Ichiro Taniuchi
Nature Reviews Immunology 9, 106–115
(February 2009); doi:10.1038/nri2489
| Summary | Full Text (HTML / PDF) |

article
Increased LIS1 expression affects human and mouse brain development
Weimin Bi et al.
Nature Genetics 41, 168–177
(February 2009); doi:10.1038/ng.302
| Summary | Full Text (HTML / PDF) |

article
The tumor suppressor Pml regulates cell fate in the developing neocortex
Tarik Regad, Cristian Bellodi, Pierluigi Nicotera & Paolo Salomoni
Nature Neuroscience 12, 132–140
(February 2009); doi:10.1038/nn.2251
| Summary | Full Text (HTML / PDF) |

news and views
PML: a tumor suppressor essential for neocortical development
Karisa C Schreck & Nicholas Gaiano
Nature Neuroscience 12, 108–110
(February 2009); doi:10.1038/nn0209-108
| Full Text (HTML / PDF) |

article
Regulation of Notch and Wingless signalling by phyllopod, a transcriptional target of the EGFR pathway
Raghavendra Nagaraj & Utpal Banerjee
The EMBO Journal 28, 337–346
(February 2009); doi:10.1038/emboj.2008.286
| Summary | Full Text (HTML / PDF) |

letter
Nodal signalling is involved in left-right asymmetry in snails
Cristina Grande & Nipam H. Patel
Nature 457, 1007–1011
(19 February 2009); doi:10.1038/nature07603
| Summary | Full Text (HTML / PDF) |

review
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
I-Cheng Ho, Tzong-Shyuan Tai & Sung-Yun Pai
Nature Reviews Immunology 9, 125–135
(February 2009); doi:10.1038/nri2476
| Summary | Full Text (HTML / PDF) |

letter
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
Michael J. Chen, Tomomasa Yokomizo, Brandon M. Zeigler, Elaine Dzierzak & Nancy A. Speck
Nature 457, 887–891
(12 February 2009); doi:10.1038/nature07619
| Summary | Full Text (HTML / PDF) |

letter
ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development
Shigeru Oshima et al.
Nature 457, 906–909
(12 February 2009); doi:10.1038/nature07575
| Summary | Full Text (HTML / PDF) |

article
Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-κB activation through Raf-1 and Syk
Sonja I Gringhuis et al.
Nature Immunology 10, 203–213
(February 2009); doi:10.1038/ni.1692
| Summary | Full Text (HTML / PDF) |

review
Epigenetic control of T-helper-cell differentiation
Christopher B. Wilson, Emily Rowell & Masayuki Sekimata
Nature Reviews Immunology 9, 91–105
(February 2009); doi:10.1038/nri2487
| Summary | Full Text (HTML / PDF) |

article
NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+-sirtuin-1-dependent pathway
Julia Skokowa et al.
Nature Medicine 15, 151–158
(February 2009); doi:10.1038/nm.1913
| Summary | Full Text (HTML / PDF) |

news and views
Vitamin B3 boosts neutrophil counts
Arati Khanna-Gupta & Nancy Berliner
Nature Medicine 15, 139–141
(February 2009); doi:10.1038/nm0209-139
| Full Text (HTML / PDF) |

article
Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis
Milan Joksimovic et al.
Nature Neuroscience 12, 125–131
(February 2009); doi:10.1038/nn.2243
| Summary | Full Text (HTML / PDF) |

news and views
Too much Sonic, too few neurons
Christopher A Fasano & Lorenz Studer
Nature Neuroscience 12, 107–108
(February 2009); doi:10.1038/nn0209-107
| Full Text (HTML / PDF) |

review
The different faces of Notch in T-helper-cell differentiation
Derk Amsen, Andrey Antov & Richard A. Flavell
Nature Reviews Immunology 9, 116–124
(February 2009); doi:10.1038/nri2488
| Summary | Full Text (HTML / PDF) |

letter
WNT11 acts as a directional cue to organize the elongation of early muscle fibres
Jérôme Gros, Olivier Serralbo & Christophe Marcelle
Nature 457, 589–593
(January 2009); doi:10.1038/nature07564
| Summary | Full Text (HTML / PDF) |

article
TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch
Irwin M Liu et al.
The EMBO Journal 28, 88–98
(January 2009); doi:10.1038/emboj.2008.266
| Summary | Full Text (HTML / PDF) |

article
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction
Koichi Kobayashi, Min Luo, Yue Zhang, David C. Wilkes, Gaoxiang Ge, Thomas Grieskamp, Chikaomi Yamada, Ting-Chun Liu, Guorui Huang, Craig T. Basson, Andreas Kispert, Daniel S. Greenspan & Thomas N. Sato
Nature Cell Biology 11, 46–55
(January 2009); doi:10.1038/ncb1811
| Summary | Full Text (HTML / PDF) |

news and views
sFRPs: a declaration of (Wnt) independence
Elisha Nathan & Eldad Tzahor
Nature Cell Biology 11, 13
(January 2009); doi:10.1038/ncb0109-13
| Full Text (HTML / PDF) |

letter
Characterization of human embryonic stem cells with features of neoplastic progression
Tamra E Werbowetski-Ogilvie et al.
Nature Biotechnology 27, 91–97
(January 2009); doi:10.1038/nbt.1516
| Summary | Full Text (HTML / PDF) |

review
Mechanotransduction in development: a growing role for contractility
Michele A. Wozniak & Christopher S. Chen
Nature Reviews Molecular Cell Biology 10, 34–43
(January 2009); doi:10.1038/nrm2592
| Summary | Full Text (HTML / PDF) |

article
γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
Pedro J Real et al.
Nature Medicine 15, 50–58
(January 2009); doi:10.1038/nm.1900
| Summary | Full Text (HTML / PDF) |

news and views
γ-secretase inhibitors: Notch so bad
Gerard C Grosveld
Nature Medicine 15, 20–21
(January 2009); doi:10.1038/nm0109-20
| Full Text (HTML / PDF) |

brief communication
Regulation of ERK activity duration by Sprouty contributes to dorsoventral patterning
Hiroshi Hanafusa, Kunihiro Matsumoto & Eisuke Nishida
Nature Cell Biology 11, 106–109
(January 2009); doi:10.1038/ncb1820
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article
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells
Tom Cupedo et al.
Nature Immunology 10, 66–74
(January 2009); doi:10.1038/ni.1668
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Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin
Carmelo Luci et al.
Nature Immunology 10, 75–82
(January 2009); doi:10.1038/ni.1681
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RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
Stephanie L Sanos et al.
Nature Immunology 10, 83–91
(January 2009); doi:10.1038/ni.1684
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Spotlight on IL-22-producing NK cell receptor-expressing mucosal lymphocytes
Karl-Johan Malmberg & Hans-Gustaf Ljunggren
Nature Immunology 10, 11–12
(January 2009); doi:10.1038/ni0109-11
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