news and views Apoptosis: eating sensibly
Christopher D. Gregory and Simon B. Brown Nature Cell Biology7, 1161–1163
(December 2005); doi:10.1038/ncb1205-1061
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article Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses
Sindy H Wei, Hugh Rosen, Melanie P Matheu, M Germana Sanna, Sheng-Kai Wang, Euijung Jo, Chi-Huey Wong, Ian Parker and Michael D Cahalan Nature Immunology6, 1228–1235
(December 2005); doi:10.1038/ni1269
| Abstract | Full Text (HTML/PDF) |
Review article Immunity by ubiquitylation: a reversible process of modification
Yun-Cai Liu, Josef Penninger and Michael Karin Nature Reviews Immunology5, 941–952
(December 2005); doi:10.1038/nri1731
| Summary | Full Text (HTML / PDF) |
review article Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms
Mukesh K. Jain and Paul M. Ridker Nature Reviews Drug Discovery4, 977–987
(December 2005); doi:10.1038/nrd1901
| Summary | Full Text (HTML / PDF) |
article The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils
Zhong-Jian Shen, Stephane Esnault and James S Malter Nature Immunology6, 1280–1287
(December 2005); doi:10.1038/ni1266
| Abstract | Full Text (HTML/PDF) |
news and views Pin1: a proline isomerase that makes you wheeze?
Paul Anderson Nature Immunology6, 1211–1212
(December 2005); doi:10.1038/ni1205-1211
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article The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Chen Zhu, Ana C Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J Khoury, Xin Xiao Zheng, Terry B Strom and Vijay K Kuchroo Nature Immunology6, 1245–1252
(December 2005); doi:10.1038/ni1271
| Abstract | Full Text (HTML/PDF) |
article Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
Marcin Kortylewski, Maciej Kujawski, Tianhong Wang, Sheng Wei, Shumin Zhang, Shari Pilon-Thomas, Guilian Niu, Heidi Kay, James Mulé, William G Kerr, Richard Jove, Drew Pardoll and Hua Yu Nature Medicine11, 1314–1321
(December 2005); doi:10.1038/nm1325
| Abstract | Full Text (HTML/PDF) |
brief communication Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
Torkel Vang, Mauro Congia, Maria Doloretta Macis, Lucia Musumeci, Valeria Orrú, Patrizia Zavattari, Konstantina Nika, Lutz Tautz, Kjetil Taskén, Francesco Cucca, Tomas Mustelin and Nunzio Bottini Nature Genetics37, 1317–1319
(December 2005); doi:10.1038/ng1673
| First Paragraph | Full Text (HTML/PDF) |
news and views Gaining insight into PTPN22 and autoimmunity
Peter K Gregersen Nature Genetics37, 1300–1302
(December 2005); doi:10.1038/ng1205-1300
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article Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
Tadashi Yokosuka, Kumiko Sakata-Sogawa, Wakana Kobayashi, Michio Hiroshima, Akiko Hashimoto-Tane, Makio Tokunaga, Michael L Dustin and Takashi Saito Nature Immunology6, 1253–1262
(December 2005); doi:10.1038/ni1272
| Abstract | Full Text (HTML/PDF) |
news and views Microclusters initiate and sustain T cell signaling
Alain Trautmann Nature Immunology6, 1213–1214
(December 2005); doi:10.1038/ni1205-1213
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November
letter The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation
Uttiya Basu, Jayanta Chaudhuri , Craig Alpert, Shilpee Dutt, Sheila Ranganath, Gang Li, Jason Patrick Schrum, John P. Manis and Frederick W. Alt Nature438, 508–511
(24 November 2005); doi:10.1038/nature04255
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article Essential function for the kinase TAK1 in innate and adaptive immune responses
Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda, Jun Ninomiya-Tsuji, Masahiro Yamamoto, Taro Kawai, Kunihiro Matsumoto, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 1087–1095
(November 2005); doi:10.1038/ni1255
| Abstract | Full Text (HTML/PDF) |
article Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
Stephen B Gauld, Robert J Benschop, Kevin T Merrell and John C Cambier Nature Immunology6, 1160–1167
(November 2005); doi:10.1038/ni1256
| Abstract | Full Text (HTML/PDF) |
news and views Unraveling B cell receptor mechanics
Jürgen Wienands Nature Immunology6, 1072–1074
(November 2005); doi:10.1038/ni1105-1072
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review article Molecular defects in T- and B-cell primary immunodeficiency diseases
Charlotte Cunningham-Rundles and Prashant P. Ponda Nature Reviews Immunology5, 880–892
(November 2005); doi:10.1038/nri1713
| Summary | Full Text (HTML / PDF) |
letter Control of B-cell responses by Toll-like receptors
Chandrashekhar Pasare and Ruslan Medzhitov Nature438, 364–368
(17 November 2005); doi:10.1038/nature04267
| First Paragraph | Full Text (HTML / PDF) |
article Essential function for the kinase TAK1 in innate and adaptive immune responses
Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda, Jun Ninomiya-Tsuji, Masahiro Yamamoto, Taro Kawai, Kunihiro Matsumoto, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 1087–1095
(November 2005); doi:10.1038/ni1255
| Abstract | Full Text (HTML/PDF) |
review article Follicular B helper T cells in antibody responses and autoimmunity
Carola G. Vinuesa, Stuart G. Tangye, Bernhard Moser and Charles R. Mackay Nature Reviews Immunology5, 853–865
(November 2005); doi:10.1038/nri1714
| Summary | Full Text (HTML / PDF) |
article Regulation of lung injury and repair by Toll-like receptors and hyaluronan
Dianhua Jiang, Jiurong Liang, Juan Fan, Shuang Yu, Suping Chen, Yi Luo, Glenn D Prestwich, Marcella M Mascarenhas, Hari G Garg, Deborah A Quinn, Robert J Homer, Daniel R Goldstein, Richard Bucala, Patty J Lee, Ruslan Medzhitov and Paul W Noble Nature Medicine11, 1173–1179
(November 2005); doi:10.1038/nm1315
| Abstract | Full Text (HTML/PDF) |
news and views TLRs play good cop, bad cop in the lung
Luke A J O'Neill Nature Medicine11, 1161–1162
(November 2005); doi:10.1038/nm1105-1161
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article Genetic variation in selenoprotein S influences inflammatory response
Joanne E Curran, Jeremy B M Jowett, Kate S Elliott, Yuan Gao, Kristi Gluschenko, Jianmin Wang, Dalia M Abel Azim, Guowen Cai, Michael C Mahaney, Anthony G Comuzzie, Thomas D Dyer, Ken R Walder, Paul Zimmet, Jean W MacCluer, Greg R Collier, Ahmed H Kissebah and John Blangero Nature Genetics37, 1234–1241
(November 2005); doi:10.1038/ng1655
| Abstract | Full Text (HTML/PDF) |
article Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Laurie E Harrington, Robin D Hatton, Paul R Mangan, Henrietta Turner, Theresa L Murphy, Kenneth M Murphy and Casey T Weaver Nature Immunology6, 1123–1132
(November 2005); doi:10.1038/ni1254
| Abstract | Full Text (HTML/PDF) |
article A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park, Zhaoxia Li, Xuexian O Yang, Seon Hee Chang, Roza Nurieva, Yi-Hong Wang, Ying Wang, Leroy Hood, Zhou Zhu, Qiang Tian and Chen Dong Nature Immunology6, 1133–1141
(November 2005); doi:10.1038/ni1261
| Abstract | Full Text (HTML/PDF) |
news and views TH-17: a giant step from TH1 and TH2
Thomas A Wynn Nature Immunology6, 1069–1070
(November 2005); doi:10.1038/ni1105-1069
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review article Fuel feeds function: energy metabolism and the T-cell response
Casey J. Fox , Peter S. Hammerman and Craig B. Thompson Nature Reviews Immunology5, 844–852
(November 2005); doi:10.1038/nri1710
| Summary | Full Text (HTML / PDF) |
news and views Hitching RIG to action
Ganes C Sen and Saumendra N Sarkar Nature Immunology6, 1074–1076
(November 2005); doi:10.1038/ni1105-1074
| Full Text (HTML / PDF) |
review article NK cells in HIV infection: Paradigm for protection or targets for ambush
Anthony S. Fauci, Domenico Mavilio and Shyam Kottilil Nature Reviews Immunology5, 835–843
(November 2005); doi:10.1038/nri1711
| Abstract | Full Text (HTML / PDF) |
article CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection
Jeffrey W Tyner, Osamu Uchida, Naohiro Kajiwara, Edy Y Kim, Anand C Patel, Mary P O'Sullivan, Michael J Walter, Reto A Schwendener, Donald N Cook, Theodore M Danoff and Michael J Holtzman Nature Medicine11, 1080–1087
(November 2005); doi:10.1038/nm1303
| Abstract
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October
article Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells
Laura Santambrogio, Ilaria Potolicchio, Shawn P Fessler, Siew-Heng Wong, Graça Raposo and Jack L Strominger Nature Immunology6, 1020–1028
(October 2005); doi:10.1038/ni1250
| Abstract | Full Text (HTML/PDF) |
news and views Dendritic cells: caspases keep them young
Peter E Jensen Nature Immunology6, 968–969
(October 2005); doi:10.1038/ni1005-968
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letter A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
Matthew R Lincoln, Alexandre Montpetit, M Zameel Cader, Janna Saarela, David A Dyment, Milvi Tiislar, Vincent Ferretti, Pentti J Tienari, A Dessa Sadovnick, Leena Peltonen, George C Ebers and Thomas J Hudson Nature Genetics37, 1108–1112
(October 2005); doi:10.1038/ng1647
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letter A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility
David Reich, Nick Patterson, Philip L De Jager, Gavin J McDonald, Alicja Waliszewska, Arti Tandon, Robin R Lincoln, Cari DeLoa, Scott A Fruhan, Philippe Cabre, Odile Bera, Gilbert Semana, M Ann Kelly, David A Francis, Kristin Ardlie, Omar Khan, Bruce A C Cree, Stephen L Hauser, Jorge R Oksenberg and David A Hafler Nature Genetics37, 1113–1118
(October 2005); doi:10.1038/ng1646
| First Paragraph | Full Text (HTML/PDF) |
letter Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
Etienne Meylan, Joseph Curran, Kay Hofmann, Darius Moradpour, Marco Binder, Ralf Bartenschlager and Jürg Tschopp Nature437, 1167–1172
(20 October 2005); doi:10.1038/nature04193
| First Paragraph | Full Text (HTML / PDF) |
article Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor
Romain Roncagalli, James E R Taylor, Shaohua Zhang, Xiaochu Shi, Riyan Chen, Mario-Ernesto Cruz-Munoz, Luo Yin, Sylvain Latour and André Veillette Nature Immunology6, 1002–1010
(October 2005); doi:10.1038/ni1242
| Abstract | Full Text (HTML/PDF) |
news and views Fine-tuning NK cell responses: it's a family affair
Marco Colonna Nature Immunology6, 961–962
(October 2005); doi:10.1038/ni1005-961
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review article Regulation of MHC class II gene expression by the class II transactivator
Walter Reith, Salomé LeibundGut-Landmann and Jean-Marc Waldburger Nature Reviews Immunology5, 793–806
(October 2005); doi:10.1038/nri1708
| Abstract | Full Text (HTML / PDF) |
letter A network-based analysis of systemic inflammation in humans
Steve E. Calvano, Wenzhong Xiao, Daniel R. Richards, Ramon M. Felciano, Henry V. Baker, Raymond J. Cho, Richard O. Chen, Bernard H. Brownstein, J. Perren Cobb, S. Kevin Tschoeke, Carol Miller-Graziano, Lyle L. Moldawer, Michael N. Mindrinos, Ronald W. Davis, Ronald G. Tompkins, Stephen F. Lowry and Inflamm and Host Response to Injury Large Scale Collab. Res. Program Nature437, 1032–1037
(13 October 2005); doi:10.1038/nature03985
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article Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins
Eugenia Leikina, Helene Delanoe-Ayari, Kamran Melikov, Myoung-Soon Cho, Andrew Chen, Alan J Waring, Wei Wang, Yongming Xie, Joseph A Loo, Robert I Lehrer and Leonid V Chernomordik Nature Immunology6, 995–1001
(October 2005); doi:10.1038/ni1248
| Abstract | Full Text (HTML/PDF) |
news and views Back to the past: new drugs from ancient molecules?
Rodney Phillips Nature Immunology6, 963–964
(October 2005); doi:10.1038/ni1005-963
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review article Cell-surface enzymes in control of leukocyte trafficking
Marko Salmi and Sirpa Jalkanen Nature Reviews Immunology5, 760–771
(October 2005); doi:10.1038/nri1705
| Abstract | Full Text (HTML / PDF) |
letter STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane
Shenyuan L. Zhang, Ying Yu, Jack Roos, J. Ashot Kozak, Thomas J. Deerinck, Mark H. Ellisman, Kenneth A. Stauderman and Michael D. Cahalan Nature437, 902–905
(06 October 2005); doi:10.1038/nature04147
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letter Apolipoprotein-mediated pathways of lipid antigen presentation
Peter van den Elzen, Salil Garg, Luis León, Manfred Brigl, Elizabeth A. Leadbetter, Jenny E. Gumperz, Chris C. Dascher, Tan-Yun Cheng, Frank M. Sacks, Petr A. Illarionov, Gurdyal S. Besra, Sally C. Kent, D. Branch Moody and Michael B. Brenner Nature437, 906–910
(06 October 2005); doi:10.1038/nature04001
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article IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
Taro Kawai, Ken Takahashi, Shintaro Sato, Cevayir Coban, Himanshu Kumar, Hiroki Kato, Ken J Ishii, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 981–988
(October 2005); doi:10.1038/ni1243
| Abstract | Full Text (HTML/PDF) |
article Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
Baohua Zhou, Michael R Comeau, Thibaut De Smedt, H Denny Liggitt, Martin E Dahl, David B Lewis, Dora Gyarmati, Theingi Aye, Daniel J Campbell and Steven F Ziegler Nature Immunology6, 1047–1053
(October 2005); doi:10.1038/ni1247
| Abstract | Full Text (HTML/PDF) |
news and views 'PPAR'ting ways with inflammation
Shannon T Bailey and Sankar Ghosh Nature Immunology6, 966–967
(October 2005); doi:10.1038/ni1005-966
| Full Text (HTML/PDF) |
review article NF-κB: linking inflammation and immunity to cancer development and progression
Michael Karin and Florian R. Greten Nature Reviews Immunology5, 749–759
(October 2005); doi:10.1038/nri1703
| Abstract | Full Text (HTML / PDF) |
article Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors
Guo-Min Deng, Lixin Zheng, Francis Ka-Ming Chan and Michael Lenardo Nature Medicine11, 1066–1072
(October 2005); doi:10.1038/nm1304
| Abstract | Full Text (HTML/PDF) |
September
letter WntD is a feedback inhibitor of Dorsal/NF-κB in Drosophila development and immunity
Michael D. Gordon, Marc S. Dionne, David S. Schneider and Roel Nusse Nature437, 746–749
(29 September 2005); doi:10.1038/nature04073
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letter Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells
Hideyuki Yoshida, Kohki Kawane , Masato Koike, Yoshimi Mori, Yasuo Uchiyama and Shigekazu Nagata Nature437, 754–758
(29 September 2005); doi:10.1038/nature03964
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letter A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
Gabriel Pascual, Amy L. Fong, Sumito Ogawa, Amir Gamliel, Andrew C. Li, Valentina Perissi, David W. Rose, Timothy M. Willson, Michael G. Rosenfeld and Christopher K. Glass Nature437, 759–763
(29 September 2005); doi:10.1038/nature03988
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article The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila
Catherine Dostert, Emmanuelle Jouanguy, Phil Irving, Laurent Troxler, Delphine Galiana-Arnoux, Charles Hetru, Jules A Hoffmann and Jean-Luc Imler Nature Immunology6, 946–953
(September 2005); doi:10.1038/ni1237
| Abstract | Full Text (HTML/PDF) |
news and views Drosophila innate immunity goes viral
Y Tony Ip Nature Immunology6, 863–864
(September 2005); doi:10.1038/ni0905-863
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review article Regulation of immune cells by local-tissue oxygen tension: HIF1α and adenosine receptors
Michail Sitkovsky and Dmitriy Lukashev Nature Reviews Immunology5, 712–721
(September 2005); doi:10.1038/nri1685 Nature Reviews Immunology AOP published online
| Abstract | Full Text (HTML / PDF) |
article Structures of complement component C3 provide insights into the function and evolution of immunity
Bert J. C. Janssen, Eric G. Huizinga, Hans C. A. Raaijmakers, Anja Roos, Mohamed R. Daha, Kristina Nilsson-Ekdahl, Bo Nilsson and Piet Gros Nature437, 505–511
(22 September 2005); doi:10.1038/nature04005
| Abstract | Full Text (HTML / PDF) |
article Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
David E Oppenheim, Scott J Roberts, Sarah L Clarke, Renata Filler, Julie M Lewis, Robert E Tigelaar, Michael Girardi and Adrian C Hayday Nature Immunology6, 928–937
(September 2005); doi:10.1038/ni1239
| Abstract | Full Text (HTML/PDF) |
brief communication PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
Domingo F Barber, Almira Bartolomé, Carmen Hernandez, Juana M Flores, Clara Redondo, Cristina Fernandez-Arias, Montserrat Camps, Thomas Rückle, Matthias K Schwarz, Santiago Rodríguez, Carlos Martinez-A, Dimitrios Balomenos, Christian Rommel and Ana C Carrera Nature Medicine11, 933–935
(September 2005); doi:10.1038/nm1291
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article Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
Montserrat Camps, Thomas Rückle, Hong Ji, Vittoria Ardissone, Felix Rintelen, Jeffrey Shaw, Chiara Ferrandi, Christian Chabert, Corine Gillieron, Bernard Françon, Thierry Martin, Denise Gretener, Dominique Perrin, Didier Leroy, Pierre-Alain Vitte, Emilio Hirsch, Matthias P Wymann, Rocco Cirillo, Matthias K Schwarz and Christian Rommel Nature Medicine11, 936–943
(September 2005); doi:10.1038/nm1284
| Abstract | Full Text (HTML/PDF) |
news and views Modulating autoimmunity: pick your PI3 kinase
Pamela S Ohashi and James R Woodgett Nature Medicine11, 924–925
(September 2005); doi:10.1038/nm0905-924
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letter WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature
Ivan B. Lobov, Sujata Rao, Thomas J. Carroll, Jefferson E. Vallance, Masataka Ito, Jennifer K. Ondr, Savita Kurup, Donald A. Glass, Millan S. Patel, Weiguo Shu, Edward E. Morrisey, Andrew P. McMahon, Gerard Karsenty and Richard A. Lang Nature437, 417–421
(15 September 2005); doi:10.1038/nature03928
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article Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses
Lianchun Wang, Mark Fuster, P Sriramarao and Jeffrey D Esko Nature Immunology6, 902–910
(September 2005); doi:10.1038/ni1233
| Abstract | Full Text (HTML/PDF) |
review article Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation
Warren J. Leonard and Rosanne Spolski Nature Reviews Immunology5, 688–698
(September 2005); doi:10.1038/nri1688
| Abstract | Full Text (HTML / PDF) |
article Notch promotes survival of pre-T cells at the β-selection checkpoint by regulating cellular metabolism
Maria Ciofani and Juan Carlos Zúñiga-Pflücker Nature Immunology6, 881–888
(September 2005); doi:10.1038/ni1234
| Abstract | Full Text (HTML/PDF) |
article An essential function for the calcium-promoted Ras inactivator in Fcγ receptor-mediated phagocytosis
Jun Zhang, Jian Guo, Ivan Dzhagalov and You-Wen He Nature Immunology6, 911–919
(September 2005); doi:10.1038/ni1232
| Abstract | Full Text (HTML/PDF) |
news and views A CAPRIciously translocating Rac adaptor
Steven Greenberg Nature Immunology6, 864–866
(September 2005); doi:10.1038/ni0905-864
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review article The Yin and Yang of type I interferon activity in bacterial infection
Thomas Decker, Mathias Müller and Silvia Stockinger Nature Reviews Immunology5, 675–687
(September 2005); doi:10.1038/nri1684
| Abstract | Full Text (HTML / PDF) |
August
letter Sporadic immunogenic tumours avoid destruction by inducing T-cell tolerance
Gerald Willimsky and Thomas Blankenstein Nature437, 141–146
(01 September 2005); doi:10.1038/nature03954
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article Pivotal function for cytoplasmic protein FROUNT in CCR2-mediated monocyte chemotaxis
Yuya Terashima, Nobuyuki Onai, Masako Murai, Masahiko Enomoto, Vongsakorn Poonpiriya, Tsuyoshi Hamada, Kazushi Motomura, Makiko Suwa, Taichi Ezaki, Tatsuya Haga, Shiro Kanegasaki and Kouji Matsushima Nature Immunology6, 827–835
(August 2005); doi:10.1038/ni1222
| Abstract | Full Text (HTML/PDF) |
review article Dendritic-cell trafficking to lymph nodes through lymphatic vessels
Gwendalyn J. Randolph, Veronique Angeli and Melody A. Swartz Nature Reviews Immunology5, 617–628
(August 2005); doi:10.1038/nri1670
| Abstract | Full Text (HTML / PDF) |
letter Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
Norihiko Watanabe, Yi-Hong Wang, Heung Kyu Lee, Tomoki Ito, Yui-Hsi Wang, Wei Cao and Yong-Jun Liu Nature436, 1181–1185
(25 August 2005); doi:10.1038/nature03886
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letter The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
Stephan Gasser, Sandra Orsulic, Eric J. Brown and David H. Raulet Nature436, 1186–1190
(25 August 2005); doi:10.1038/nature03884
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article Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes
James I. Elliott, Annmarie Surprenant, Federica M. Marelli-Berg, Joanne C. Cooper, Robin L. Cassady-Cain, Carol Wooding, Kenneth Linton, Denis R. Alexander and Christopher F. Higgins Nature Cell Biology7, 808–816
(August 2005); doi:10.1038/ncb1279
| Abstract | Full Text (HTML/PDF) |
article Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
Wouter J de Jonge, Esmerij P van der Zanden, Frans O The, Maarten F Bijlsma, David J van Westerloo, Roelof J Bennink, Hans-Rudolf Berthoud, Satoshi Uematsu, Shizuo Akira, Rene M van den Wijngaard and Guy E Boeckxstaens Nature Immunology6, 844–851
(August 2005); doi:10.1038/ni1229
| Abstract | Full Text (HTML/PDF) |
news and views It takes nerve to dampen inflammation
Christine N Metz and Kevin J Tracey Nature Immunology6, 756–757
(August 2005); doi:10.1038/ni0805-756
| Full Text (HTML/PDF) |
review article Regulation of gene-activation pathways by PIAS proteins in the immune system
Ke Shuai and Bin Liu Nature Reviews Immunology5, 593–605
(August 2005); doi:10.1038/nri1667
| Summary | Full Text (HTML / PDF) |
review article The TCL1 family of oncoproteins: co-activators of transformation
Michael A. Teitell Nature Reviews Cancer5, 640–648
(August 2005); doi:10.1038/nrc1672
| Summary | Full Text (HTML / PDF) |
letter Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
R. Lu, M. Maduro, F. Li, H. W. Li, G. Broitman-Maduro, W. X. Li and S. W. Ding Nature436, 1040–1043
(18 August 2005); doi:10.1038/nature03870
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letter RNA interference is an antiviral defence mechanism in Caenorhabditis elegans
Courtney Wilkins, Ryan Dishongh, Steve C. Moore, Michael A. Whitt, Marie Chow and Khaled Machaca Nature436, 1044–1047
(18 August 2005); doi:10.1038/nature03957
| First Paragraph | Full Text (HTML / PDF) |
insight Unravelling hepatitis C virus replication from genome to function
Brett D. Lindenbach and Charles M. Rice Nature436, 933–938
(18 August 2005); doi:10.1038/nature04077
| Abstract | Full Text (HTML / PDF) |
insight Evasion of intracellular host defence by hepatitis C virus
Michael Gale Jr and Eileen M. Foy Nature436, 939–945
(18 August 2005); doi:10.1038/nature04078
| Abstract | Full Text (HTML / PDF) |
insight Adaptive immune responses in acute and chronic hepatitis C virus infection
David G. Bowen and Christopher M. Walker Nature436, 946–952
(18 August 2005); doi:10.1038/nature04079
| Abstract | Full Text (HTML / PDF) |
review article Interleukin-1 and neuronal injury
Stuart M. Allan, Pippa J. Tyrrell and Nancy J. Rothwell Nature Reviews Immunology5, 629–640
(August 2005); doi:10.1038/nri1664
| Abstract | Full Text (HTML / PDF) |
letter Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis
Daewoong Jo, Danya Liu, Shan Yao, Robert D Collins and Jacek Hawiger Nature Medicine11, 892–898
(August 2005); doi:10.1038/nm1269
| First Paragraph | Full Text (HTML/PDF) |
article Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse
Pia P Yachi, Jeanette Ampudia, Nicholas R J Gascoigne and Tomasz Zal Nature Immunology6, 785–792
(August 2005); doi:10.1038/ni1220
| Abstract | Full Text (HTML/PDF) |
review article Regulation of immune responses by L-arginine metabolism
Vincenzo Bronte and Paola Zanovello Nature Reviews Immunology5, 641–654
(August 2005); doi:10.1038/nri1668
| Abstract | Full Text (HTML / PDF) |
article Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
U Salzer, H M Chapel, A D B Webster, Q Pan-Hammarström, A Schmitt-Graeff, M Schlesier, H H Peter, J K Rockstroh, P Schneider, A A Schäffer, L Hammarström and B Grimbacher Nature Genetics37, 820–828
(August 2005); doi:10.1038/ng1600
| Abstract | Full Text (HTML/PDF) |
article TACI is mutant in common variable immunodeficiency and IgA deficiency
Emanuela Castigli, Stephen A Wilson, Lilit Garibyan, Rima Rachid, Francisco Bonilla, Lynda Schneider and Raif S Geha Nature Genetics37, 829–834
(August 2005); doi:10.1038/ng1601
| Abstract | Full Text (HTML/PDF) |
news and views Unraveling TACIt functions
Flavius Martin and Vishva M Dixit Nature Genetics37, 793–794
(August 2005); doi:10.1038/ng0805-793
| Full Text (HTML/PDF) |
review article Leukotriene modifiers as potential therapeutics for cardiovascular disease
Colin D. Funk Nature Reviews Drug Discovery4, 664–672
(August 2005); doi:10.1038/nrd1796
| Abstract | Full Text (HTML / PDF) |
letter Licensing of natural killer cells by host major histocompatibility complex class I molecules
Sungjin Kim, Jennifer Poursine-Laurent, Steven M. Truscott, Lonnie Lybarger, Yun-Jeong Song, Liping Yang, Anthony R. French, John B. Sunwoo, Suzanne Lemieux, Ted H. Hansen and Wayne M. Yokoyama Nature436, 709–713
(04 August 2005); doi:10.1038/nature03847
| First Paragraph | Full Text (HTML / PDF) |
article Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
Giorgio Napolitani, Andrea Rinaldi, Francesco Bertoni, Federica Sallusto and Antonio Lanzavecchia Nature Immunology6, 769–776
(August 2005); doi:10.1038/ni1223
| Abstract | Full Text (HTML/PDF) |
news and views 'TaiLoRing' the response of dendritic cells to pathogens
Bernard Malissen and Jonathan J Ewbank Nature Immunology6, 749–750
(August 2005); doi:10.1038/ni0805-749
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article Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
Michael Martin, Kunal Rehani, Richard S Jope and Suzanne M Michalek Nature Immunology6, 777–784
(August 2005); doi:10.1038/ni1221
| Abstract | Full Text (HTML/PDF) |
news and views GSK3: an in-Toll-erant protein kinase?
James R Woodgett and Pamela S Ohashi Nature Immunology6, 751–752
(August 2005); doi:10.1038/ni0805-751
| Full Text (HTML/PDF) |
review article The vagus nerve and the nicotinic anti-inflammatory pathway
Luis Ulloa Nature Reviews Drug Discovery4, 673–684
(August 2005); doi:10.1038/nrd1797
| Abstract | Full Text (HTML / PDF) |
July
article A critical function for type I interferons in cancer immunoediting
Gavin P Dunn, Allen T Bruce, Kathleen C F Sheehan, Vijay Shankaran, Ravindra Uppaluri, Jack D Bui, Mark S Diamond, Catherine M Koebel, Cora Arthur, J Michael White and Robert D Schreiber Nature Immunology6, 722–729
(July 2005); doi:10.1038/ni1213
| Abstract | Full Text (HTML/PDF) |
news and views Type I interferon and cancer immunoediting
Mark J Smyth Nature Immunology6, 646–648
(July 2005); doi:10.1038/ni0705-646
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review article Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network
Hugh Rosen and Edward J. Goetzl Nature Reviews Immunology5, 560–570
(July 2005); doi:10.1038/nri1650
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article Notch signaling
controls the generation and differentiation of early T lineage
progenitors Arivazhagan Sambandam, Ivan Maillard, Valerie P Zediak,
Lanwei Xu, Rachel M Gerstein, Jon C Aster, Warren S Pear and Avinash
Bhandoola Nature Immunology6, 663–670 (July 2005);
doi:10.1038/ni1216 | Abstract | Full Text (HTML/PDF)
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article Requirement for Notch1
signals at sequential early stages of intrathymic T cell
development Joanne B Tan, Ioana Visan, Julie S Yuan and Cynthia J
Guidos Nature Immunology6, 671–679 (July 2005);
doi:10.1038/ni1217 | Abstract | Full Text (HTML/PDF)
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article Inhibitors of
γ-secretase block in vivo and in vitro T helper type 1
polarization by preventing Notch upregulation of Tbx21 Lisa M
Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G
Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer, Lisa
Kostura, Abdul H Fauq, Katherine Simpson, Kimberly A Such, Lucio Miele, Todd E
Golde, Stephen D Miller and Barbara A Osborne Nature Immunology6, 680–688 (July 2005); doi:10.1038/ni1209 | Abstract | Full Text (HTML/PDF)
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news and views Notch in
lymphopoiesis and T cell polarization Harald von Boehmer Nature
Immunology6, 641–642 (July 2005); doi:10.1038/ni0705-641 | Full Text
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review article Intracellular
signalling controlling integrin activation in lymphocytes Tatsuo
Kinashi Nature Reviews Immunology5, 546–559 (July 2005);
doi:10.1038/nri1646 | Abstract | Full Text (HTML /
PDF) |
letter Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
Stefano Pluchino, Lucia Zanotti, Barbara Rossi, Elena Brambilla, Linda Ottoboni, Giuliana Salani, Marianna Martinello, Alessandro Cattalini, Alessandra Bergami, Roberto Furlan, Giancarlo Comi, Gabriela Constantin and Gianvito Martino Nature436, 266–271
(14 July 2005); doi:10.1038/nature03889
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article Endosome-to-cytosol transport of viral nucleocapsids
Isabelle Le Blanc, Pierre-Philippe Luyet, Véronique Pons, Charles Ferguson, Neil Emans, Anne Petiot, Nathalie Mayran, Nicolas Demaurex, Julien Fauré, Rémy Sadoul, Robert G. Parton and J. Gruenberg Nature Cell Biology7, 653–664
(July 2005); doi:10.1038/ncb1269
| Abstract | Full Text (HTML/PDF) |
news and views Viral entry: a detour through multivesicular bodies
Pradeep Uchil and Walther Mothes Nature Cell Biology7, 641–642
(July 2005); doi:10.1038/ncb0705-641
| Full Text (HTML/PDF) |
article Suppressor of cytokine signaling 1 is required for the differentiation of CD4+ T cells
Ian M Catlett and Stephen M Hedrick Nature Immunology6, 715–721
(July 2005); doi:10.1038/ni1211
| Abstract | Full Text (HTML/PDF) |
news and views A plague of autoantibodies
Vigo Heissmeyer, K Mark Ansel and Anjana Rao Nature Immunology6, 642–643
(July 2005); doi:10.1038/ni1214
| Full Text (HTML/PDF) |
review article Tuning immune responses: diversity and adaptation of the immunological synapse
Peter Friedl, Annemieke Th. den Boer and Matthias Gunzer Nature Reviews Immunology5, 532–545
(July 2005); doi:10.1038/nri1647
| Summary | Full Text (HTML / PDF) |
letter Angiotensin-converting enzyme 2 protects from severe acute lung failure
Yumiko Imai, Keiji Kuba, Shuan Rao, Yi Huan, Feng Guo, Bin Guan, Peng Yang, Renu Sarao, Teiji Wada, Howard Leong-Poi, Michael A. Crackower, Akiyoshi Fukamizu, Chi-Chung Hui, Lutz Hein, Stefan Uhlig, Arthur S. Slutsky, Chengyu Jiang and Josef M. Penninger Nature436, 112–116
(07 July 2005); doi:10.1038/nature03712
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article CD70+ antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa
Amale Laouar, Viraga Haridas, Dorothy Vargas, Xia Zhinan, David Chaplin, Rene A W van Lier and N Manjunath Nature Immunology6, 698–706
(July 2005); doi:10.1038/ni1212
| Abstract | Full Text (HTML/PDF) |
news and views Affecting the effectors: a kick in the gut?
Cecilia Johansson and Brian L Kelsall Nature Immunology6, 644–646
(July 2005); doi:10.1038/ni0705-644
| Full Text (HTML/PDF) |
review article New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions
Christopher A. Hunter Nature Reviews Immunology5, 521–531
(July 2005); doi:10.1038/nri1648
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review article Role of the Immune system in chronic pain
Fabien Marchand, Mauro Perretti and Stephen B. McMahon Nature Reviews Neuroscience6, 521–532
(July 2005); doi:10.1038/nrn1700
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June
article Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1
Fabio M V Rossi, Stephane Y Corbel, Jasmeen S Merzaban, Douglas A Carlow, Klaus Gossens, Jeffrey Duenas, Leslie So, Lin Yi and Hermann J Ziltener Nature Immunology6, 626–634
(June 2005); doi:10.1038/ni1203
| Abstract | Full Text (HTML/PDF) |
review article Negative regulation of Toll-like receptor-mediated immune responses
Foo Y. Liew, Damo Xu, Elizabeth K. Brint and Luke A. J. O'Neill Nature Reviews Immunology5, 446–458
(June 2005); doi:10.1038/nri1630
| Abstract | Full Text (HTML / PDF) |
article Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor
Georgios Skiniotis, Martin J Boulanger, K Christopher Garcia and Thomas Walz Nature Structural and Molecular Biology12, 545–551
(June 2005); doi:10.1038/nsmb941
| Abstract | Full Text (HTML/PDF) |
news and views Bow to your partner for signaling
Heike M Hermanns, Gerhard Müller-Newen, Peter C Heinrich and Serge Haan Nature Structural and Molecular Biology12, 476–478
(June 2005); doi:10.1038/nsmb0605-476
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article ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
Atsushi Matsuzawa, Kaoru Saegusa, Takuya Noguchi, Chiharu Sadamitsu, Hideki Nishitoh, Shigenori Nagai, Shigeo Koyasu, Kunihiro Matsumoto, Kohsuke Takeda and Hidenori Ichijo Nature Immunology6, 587–592
(June 2005); doi:10.1038/ni1200
| Abstract | Full Text (HTML/PDF) |
news and views Linking stress to immunity?
Bing Su Nature Immunology6, 541–542
(June 2005); doi:10.1038/ni0605-541
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review article Recognition of lipid antigens by T cells
Gennaro De Libero and Lucia Mori Nature Reviews Immunology5, 485–496
(June 2005); doi:10.1038/nri1631
| Summary | Full Text (HTML / PDF) |
letter Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
Helena Jonsson, Paul Allen and Stanford L Peng Nature Medicine11, 666–671
(June 2005); doi:10.1038/nm1248
| First Paragraph | Full Text (HTML/PDF) |
news and views A fork in the pathway to inflammation and arthritis
Foo Y Liew and Iain B McInnes Nature Medicine11, 601–602
(June 2005); doi:10.1038/nm0605-601
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article Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1
Hyewon Phee, Robert T Abraham and Arthur Weiss Nature Immunology6, 608–617
(June 2005); doi:10.1038/ni1199
| Abstract | Full Text (HTML/PDF) |
article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
Senad Divanovic, Aurelien Trompette, Sowsan F Atabani, Rajat Madan, Douglas T Golenbock, Alberto Visintin, Robert W Finberg, Alexander Tarakhovsky, Stefanie N Vogel, Yasmine Belkaid, Evelyn A Kurt-Jones and Christopher L Karp Nature Immunology6, 571–578
(June 2005); doi:10.1038/ni1198
| Abstract | Full Text (HTML/PDF) |
review article Mammalian defensins in the antimicrobial immune response
Michael E Selsted and Andre J Ouellette Nature Immunology6, 551–557
(June 2005); doi:10.1038/ni1206
| Abstract | Full Text (HTML/PDF) |
review article Transcriptional networks in developing and mature B cells
Patrick Matthias and Antonius G. Rolink Nature Reviews Immunology5, 497–508
(June 2005); doi:10.1038/nri1633
| Summary | Full Text (HTML / PDF) |
article TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells
Stephan R Krutzik, Belinda Tan, Huiying Li, Maria Teresa Ochoa, Philip T Liu, Sarah E Sharfstein, Thomas G Graeber, Peter A Sieling, Yong-Jun Liu, Thomas H Rea, Barry R Bloom and Robert L Modlin Nature Medicine11, 653–660
(June 2005); doi:10.1038/nm1246
| Abstract | Full Text (HTML/PDF) |
article Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection
Marie-Pierre Desrosiers, Agnieszka Kielczewska, J-C Loredo-Osti, Sonia Girard Adam, Andrew P Makrigiannis, Suzanne Lemieux, Trung Pham, Melissa B Lodoen, Kenneth Morgan, Lewis L Lanier and Silvia M Vidal Nature Genetics37, 593–599
(June 2005); doi:10.1038/ng1564
| Abstract | Full Text (HTML/PDF) |
news and views Antiviral synergism
Mary Carrington Nature Genetics37, 565–566
(June 2005); doi:10.1038/ng0605-565
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article Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
Jessica A Hamerman, Nadia K Tchao, Clifford A Lowell and Lewis L Lanier Nature Immunology6, 579–586
(June 2005); doi:10.1038/ni1204
| Abstract | Full Text (HTML/PDF) |
article Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ
Yasmina Laouar, Fayyaz S Sutterwala, Leonid Gorelik and Richard A Flavell Nature Immunology6, 600–607
(June 2005); doi:10.1038/ni1197
| Abstract | Full Text (HTML/PDF) |
review article Control of lymphocyte development by nuclear factor-κB
Ulrich Siebenlist, Keith Brown and Estefania Claudio Nature Reviews Immunology5, 435–445
(June 2005); doi:10.1038/nri1629
| Summary | Full Text (HTML / PDF) |
May
article A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
Carola G. Vinuesa, Matthew C. Cook, Constanza Angelucci, Vicki Athanasopoulos, Lixin Rui, Kim M. Hill, Di Yu, Heather Domaschenz, Belinda Whittle, Teresa Lambe, Ian S. Roberts, Richard R. Copley, John I. Bell, Richard J. Cornall and Christopher C. Goodnow Nature435, 452–458
(26 May 2005); doi:10.1038/nature03555
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article T cell costimulation by chemokine receptors
Barbara Molon, Giorgia Gri, Monica Bettella, Concepción Gómez-Moutón, Antonio Lanzavecchia, Carlos Martínez-A, Santos Mañes and Antonella Viola Nature Immunology6, 465–471
(May 2005); doi:10.1038/ni1191
| Abstract | Full Text (HTML/PDF) |
review article Regulators of apoptosis: suitable targets for immune therapy of cancer
Mads Hald Andersen , Jürgen C. Becker and Per thor Straten Nature Reviews Drug Discovery4, 399–409
(May 2005); doi:10.1038/nrd1717
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article Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines
Revital Shamri, Valentin Grabovsky, Jean–Marc Gauguet, Sara Feigelson, Eugenia Manevich, Waldemar Kolanus, Martyn K Robinson, Donald E Staunton, Ulrich H von Andrian and Ronen Alon Nature Immunology6, 497–506
(May 2005); doi:10.1038/ni1194
| Abstract | Full Text (HTML/PDF) |
news and views Integrin activation under flow: a local affair
Carlo Laudanna Nature Immunology6, 429–430
(May 2005); doi:10.1038/ni0505-429
| Full Text (HTML/PDF) |
article Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus
Tal I Arnon, Hagit Achdout, Ofer Levi, Gal Markel, Nivin Saleh, Gil Katz, Roi Gazit, Tsufit Gonen-Gross, Jacob Hanna, Efrat Nahari, Angel Porgador, Alik Honigman, Bodo Plachter, Dror Mevorach, Dana G Wolf and Ofer Mandelboim Nature Immunology6, 515–523
(May 2005); doi:10.1038/ni1190
| Abstract | Full Text (HTML/PDF) |
article Egr-2 and Egr-3 are negative regulators of T cell activation
Meredith Safford, Samuel Collins, Michael A Lutz, Amy Allen, Ching-Tai Huang, Jeanne Kowalski, Amanda Blackford, Maureen R Horton, Charles Drake, Ronald H Schwartz and Jonathan D Powell Nature Immunology6, 472–480
(May 2005); doi:10.1038/ni1193
| Abstract | Full Text (HTML/PDF) |
review article Mechanisms of type-I- and type-II-interferon-mediated signalling
Leonidas C. Platanias Nature Reviews Immunology5, 375–386
(May 2005); doi:10.1038/nri1604
| Summary | Full Text (HTML / PDF) |
news and views Do-all receptor takes on coagulation, inflammation
Charles Esmon Nature Medicine11, 475–477
(May 2005); doi:10.1038/nm0505-475
| Full Text (HTML/PDF) |
news and views IRF-7 triggers the interferon alarm
Myrto Raftopoulou
Nature Cell Biology7, 459
(May 2005); doi:10.1038/ncb0505-459
| Full Text (HTML/PDF) |
article TIM-1 induces T cell activation and inhibits the development of peripheral tolerance
Sarah E Umetsu, Wan-Ling Lee, Jennifer J McIntire, Laura Downey, Bharati Sanjanwala, Omid Akbari, Gerald J Berry, Haruo Nagumo, Gordon J Freeman, Dale T Umetsu and Rosemarie H DeKruyff Nature Immunology6, 447–454
(May 2005); doi:10.1038/ni1186
| Abstract | Full Text (HTML/PDF) |
article TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation
Jennifer Hartt Meyers, Sumone Chakravarti, David Schlesinger, Zsolt Illes, Hanspeter Waldner, Sarah E Umetsu, James Kenny, Xin Xiao Zheng, Dale T Umetsu, Rosemarie H DeKruyff, Terry B Strom and Vijay K Kuchroo Nature Immunology6, 455–464
(May 2005); doi:10.1038/ni1185
| Abstract | Full Text (HTML/PDF) |
review article Interactions of NF-κB with chromatin: the art of being at the right place at the right time
Gioacchino Natoli, Simona Saccani, Daniela Bosisio and Ivan Marazzi Nature Immunology6, 439–445
(May 2005); doi:10.1038/ni1196
| Abstract | Full Text (HTML/PDF) |
review article A new self: MHC-class-I-independent Natural-killer-cell self-tolerance
Vinay Kumar and Megan E. McNerney Nature Reviews Immunology5, 363–374
(May 2005); doi:10.1038/nri1603
| Summary | Full Text (HTML / PDF) |
April
letters to nature IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
Toby Lawrence , Magali Bebien, George Y. Liu, Victor Nizet and Michael Karin Nature434, 1138–1143
(28 April 2005); doi:10.1038/nature03491
| First Paragraph | Full Text (HTML / PDF) |
letters to nature Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells Qingsheng Li, Lijie Duan, Jacob D.Estes, Zhong-Min Ma, Tracy Rourke, Yichuan Wang, Cavan Reilly, John Carlis, Christopher J.Miller and Ashley T.Haase Nature434, 1148–1152
(28 April 2005); doi:10.1038/nature03513
| First Paragraph | Full Text (HTML / PDF) |
review article Natural regulatory T cells in infectious disease
Yasmine Belkaid and Barry T Rouse Nature Immunology6, 353–360
(April 2005); doi:10.1038/ni1181
| Abstract | Full Text (HTML/PDF) |
review article Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
Shimon Sakaguchi Nature Immunology6, 345–352
(April 2005); doi:10.1038/ni1178
| Abstract | Full Text (HTML/PDF) |
review article TEC-family kinases: regulators of T-helper-cell differentiation
Pamela L. Schwartzberg, Lisa D. Finkelstein and Julie A. Readinger Nature Reviews Immunology5, 284–295
(April 2005); doi:10.1038/nri1591
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letters to nature Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
Kenya Honda, Yusuke Ohba, Hideyuki Yanai, Hideo Negishi, Tatsuaki Mizutani, Akinori Takaoka, Choji Taya and Tadatsugu Taniguchi Nature434, 1035–1040
(21 April 2005); doi:10.1038/nature03547
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article The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
Guangping Sun, Xiaolong Liu, Peter Mercado, S Rhiannon Jenkinson, Magdalini Kypriotou, Lionel Feigenbaum, Philippe Galéra and Rémy Bosselut Nature Immunology6, 373–381
(April 2005); doi:10.1038/ni1183
| Abstract | Full Text (HTML/PDF) |
news and views Switching sides: transcriptional control of CD4 thymocyte lineage commitment
Rose Zamoyska Nature Immunology6, 363–364
(April 2005); doi:10.1038/ni0405-363
| Full Text (HTML/PDF) |
review article Heat-shock proteins induce T-cell regulation of chronic inflammation
Willem van Eden, Ruurd van der Zee and Berent Prakken Nature Reviews Immunology5, 318–330
(April 2005); doi:10.1038/nri1593
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review article Immunosuppressive networks in the tumour environment and their therapeutic relevance
Weiping Zou Nature Reviews Cancer5, 263–274
(April 2005); doi:10.1038/nrc1586
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article Reverse engineering of regulatory networks in human B cells
Katia Basso, Adam A Margolin, Gustavo Stolovitzky, Ulf Klein, Riccardo Dalla-Favera and Andrea Califano Nature Genetics37, 382–390
(April 2005); doi:10.1038/ng1532
| Abstract | Full Text (HTML/PDF) |
research article Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
Adam D Judge, Vandana Sood, Janet R Shaw, Dianne Fang, Kevin McClintock and Ian MacLachlan Nature Biotechnology23, 457–462
(April 2005); doi:10.1038/nbt1081
| First Paragraph | Full Text (HTML/PDF) |
article Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases
Jesus M Salvador, Paul R Mittelstadt, Tad Guszczynski, Terry D Copeland, Hiroshi Yamaguchi, Ettore Appella, Albert J Fornace and Jr Jonathan D Ashwell Nature Immunology6, 390–395
(April 2005); doi:10.1038/ni1177
| Abstract | Full Text (HTML/PDF) |
article The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway
Jesus M Salvador, Paul R Mittelstadt, Galina I Belova, Albert J Fornace and Jr Jonathan D Ashwell Nature Immunology6, 396–402
(April 2005); doi:10.1038/ni1176
| Abstract | Full Text (HTML/PDF) |
news and views MAPK p38: alternative and nonstressful in T cells
Christopher E Rudd Nature Immunology6, 368–370
(April 2005); doi:10.1038/ni0405-368
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review article Mechanisms of suppression by suppressor T cells
Harald von Boehmer Nature Immunology6, 338–344
(April 2005); doi:10.1038/ni1180
| Abstract | Full Text (HTML/PDF) |
review article Dendritic cells as therapeutic vaccines against cancer
Jacques Banchereau and A. Karolina Palucka Nature Reviews Immunology5, 296–306
(April 2005); doi:10.1038/nri1592
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review article Mechanisms of B-cell lymphoma pathogenesis
Ralf Küppers Nature Reviews Cancer5, 251–262
(April 2005); doi:10.1038/nrc1589
| Summary | Full Text (HTML / PDF) |
letters to nature IRF-7 is the master regulator of type-I interferon-dependent immune responses
Kenya Honda, Hideyuki Yanai, Hideo Negishi, Masataka Asagiri, Mitsuharu Sato, Tatsuaki Mizutani, Naoya Shimada, Yusuke Ohba, Akinori Takaoka, Nobuaki Yoshida and Tadatsugu Taniguchi Nature434, 772–777
(07 April 2005); doi:10.1038/nature03464
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letters to nature Ipr1 gene mediates innate immunity to tuberculosis
Hui Pan, Bo-Shiun Yan, Mauricio Rojas , Yuriy V. Shebzukhov, Hongwei Zhou, Lester Kobzik, Darren E. Higgins, Mark J. Daly, Barry R. Bloom and Igor Kramnik Nature434, 767–772
(07 April 2005); doi:10.1038/nature03419
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news and views Tuberculosis: The genetics of vulnerability
Nada Jabado and Philippe Gros Nature434, 709–711
(07 April 2005); doi:10.1038/434709a
| Full Text (HTML / PDF) |
article The chemokine receptor D6 limits the inflammatory response in vivo
Thomas Jamieson, Donald N Cook, Robert J B Nibbs, Antal Rot, Colin Nixon, Pauline Mclean, Antonio Alcami, Sergio A Lira, Maria Wiekowski and Gerard J Graham Nature Immunology6, 403–411
(April 2005); doi:10.1038/ni1182
| Abstract | Full Text (HTML/PDF) |
news and views Inflammatory chemokines: tuned in, turned on, dropped out
Craig Gerard Nature Immunology6, 366–368
(April 2005); doi:10.1038/ni0405-366
| Full Text (HTML/PDF) |
review article A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
Jason D Fontenot and Alexander Y Rudensky Nature Immunology6, 331–337
(April 2005); doi:10.1038/ni1179
| Abstract | Full Text (HTML/PDF) |
review article Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
C. M. Hawrylowicz and A. O'Garra Nature Reviews Immunology5, 271–283
(2005); doi:10.1038/nri1589
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letter A chimeric human-cat fusion protein blocks cat-induced allergy
Daocheng Zhu, Christopher L Kepley, Ke Zhang, Tetsuya Terada, Takechiyo Yamada and Andrew Saxon Nature Medicine11, 446–449
(April 2005); doi:10.1038/nm1219
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news and views Nipping cat allergy with fusion proteins
Janet Kalesnikoff and Stephen J Galli Nature Medicine11, 381–382
(April 2005); doi:10.1038/nm0405-381
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letter Regulation of NKT cell development by SAP, the protein defective in XLP
Kim E Nichols, Jamie Hom, Shun-You Gong, Arupa Ganguly, Cindy S Ma, Jennifer L Cannons, Stuart G Tangye, Pamela L Schwartzberg, Gary A Koretzky and Paul L Stein Nature Medicine11, 340–345
(March 2005); doi:10.1038/nm1189
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news and views The need for natural killer T cells
H Robson MacDonald and Jens Schümann Nature Medicine11, 256–257
(March 2005); doi:10.1038/nm0305-256
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March
letters to nature Recognition of bacterial glycosphingolipids by natural killer T cells
Yuki Kinjo, Douglass Wu, Gisen Kim, Guo-Wen Xing, Michael A. Poles, David D. Ho, Moriya Tsuji, Kazuyoshi Kawahara, Chi-Huey Wong and Mitchell Kronenberg Nature434, 520–525
(24 March 2005); doi:10.1038/nature03407
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letters to nature Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
Jochen Mattner, Kristin L. DeBord, Nahed Ismail, Randal D. Goff, Carlos Cantu III, Dapeng Zhou, Pierre Saint-Mezard, Vivien Wang, Ying Gao, Ning Yin, Kasper Hoebe, Olaf Schneewind, David Walker, Bruce Beutler, Luc Teyton, Paul B. Savage and Albert Bendelac Nature434, 525–529
(24 March 2005); doi:10.1038/nature03408
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article A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent
Mona K Tewari, Gomathinayagam Sinnathamby, Deepa Rajagopal and Laurence C Eisenlohr Nature Immunology6, 287–294
(March 2005); doi:10.1038/ni1171
| Abstract | Full Text (HTML/PDF) |
article Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase
Catherine van Vliet, Patricia E Bukczynska, Michelle A Puryer, Christine M Sadek, Benjamin J Shields, Michel L Tremblay and Tony Tiganis Nature Immunology6, 253–260
(March 2005); doi:10.1038/ni1169
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article Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
Hans Christian Probst, Kathy McCoy, Taku Okazaki, Tasuku Honjo and Maries van den Broek Nature Immunology6, 280–286
(March 2005); doi:10.1038/ni1165
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news and views Dendritic cells giveth and taketh away
Abul K Abbas and Arlene H Sharpe Nature Immunology6, 227–228
(March 2005); doi:10.1038/ni0305-227
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review article Regulation of plasma-cell development
Miriam Shapiro-Shelef and Kathryn Calame Nature Reviews Immunology5, 230–242
(March 2005); doi:10.1038/nri1572
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article The fibrin-derived peptide Bβ15-42 protects the myocardium against ischemia-reperfusion injury
Peter Petzelbauer, Paula A Zacharowski, Yasuhiro Miyazaki, Peter Friedl, Georg Wickenhauser, Francis J Castellino, Marion Gröger, Klaus Wolff and Kai Zacharowski Nature Medicine11, 298–304
(March 2005); doi:10.1038/nm1198
| Abstract | Full Text (HTML/PDF) |
letters to nature Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
Michelle Krogsgaard, Qi-jing Li, Cenk Sumen, Johannes B. Huppa, Morgan Huse and Mark M. Davis Nature434, 238–243
(10 March 2005); doi:10.1038/nature03391
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letters to nature Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
Akinori Takaoka, Hideyuki Yanai, Seiji Kondo, Gordon Duncan, Hideo Negishi, Tatsuaki Mizutani, Shin-ichi Kano, Kenya Honda, Yusuke Ohba, Tak W. Mak and Tadatsugu Taniguchi Nature434, 243–249
(10 March 2005); doi:10.1038/nature03308
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article STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
Ferenc A Scheeren, Marianne Naspetti, Sean Diehl, Remko Schotte, Maho Nagasawa, Erwin Wijnands, Ramon Gimeno, Florry A Vyth-Dreese, Bianca Blom and Hergen Spits Nature Immunology6, 303–313
(March 2005); doi:10.1038/ni1172
| Abstract | Full Text (HTML/PDF) |
review article MHC class I molecules and kirs in human history, health and survival
Peter Parham Nature Reviews Immunology AOP published online 18 February 2005; doi:10.1038/nri1570
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letters to nature Cross-presentation by intercellular peptide transfer through gap junctions
Joost Neijssen, Carla Herberts, Jan Wouter Drijfhout, Eric Reits, Lennert Janssen and Jacques Neefjes Nature434, 83–88
(03 March 2005); doi:10.1038/nature03290
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news and views Coupling and cross-presentation
William R. Heath and Francis R. Carbone Nature434, 27–28
(03 March 2005); doi:10.1038/434027a
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letters to nature CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
Edith M. Janssen, Nathalie M. Droin, Edward E. Lemmens, Michael J. Pinkoski, Steven J. Bensinger, Benjamin D. Ehst, Thomas S. Griffith, Douglas R. Green and Stephen P. Schoenberger Nature434, 88–93
(03 March 2005); doi:10.1038/nature03337
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article Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse
Timothy S Gomez, Michael J Hamann, Sean McCarney, Doris N Savoy, Casey M Lubking, Michael P Heldebrant, Christine M Labno, David J McKean, Mark A McNiven, Janis K Burkhardt and Daniel D Billadeau Nature Immunology6, 261–270
(March 2005); doi:10.1038/ni1168
| Abstract | Full Text (HTML/PDF) |
review article The role of BH3-only proteins in the immune system
Andreas Strasser Nature Reviews Immunology5, 189–200
(March 2005); doi:10.1038/nri1568
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article Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
Veit Hornung, Margit Guenthner-Biller, Carole Bourquin, Andrea Ablasser, Martin Schlee, Satoshi Uematsu, Anne Noronha, Muthiah Manoharan, Shizuo Akira, Antonin de Fougerolles, Stefan Endres and Gunther Hartmann Nature Medicine11, 263–270
(March 2005); doi:10.1038/nm1191
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news and views Sensing the danger in RNA
Marjorie A Robbins and John J Rossi Nature Medicine11, 250–251
(March 2005); doi:10.1038/nm0305-250
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article Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
Melanie Greter, Frank L Heppner, Maria P Lemos, Bernhard M Odermatt, Norbert Goebels, Terri Laufer, Randolph J Noelle and Burkhard Becher Nature Medicine11, 328–334
(March 2005); doi:10.1038/nm1197
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letter Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
Eileen J McMahon, Samantha L Bailey, Carol Vanderlugt Castenada, Hanspeter Waldner and Stephen D Miller Nature Medicine11, 335–339
(March 2005); doi:10.1038/nm1202
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news and views Multiple sclerosis: trapped in deadly glue
Michael Platten and Lawrence Steinman Nature Medicine11, 252–253
(March 2005); doi:10.1038/nm0305-252
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February
article The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
Xiao He, Xi He, Vibhuti P. Dave, Yi Zhang, Xiang Hua, Emmanuelle Nicolas, Weihong Xu, Bruce A. Roe and Dietmar J. Kappes Nature433, 826–833
(24 February 2005); doi:10.1038/nature03338
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letters to nature Toll-like receptor 3 promotes cross-priming to virus-infected cells
Oliver Schulz, Sandra S. Diebold, Margaret Chen, Tanja I. Näslund, Martijn A. Nolte, Lena Alexopoulou, Yasu-Taka Azuma, Richard A. Flavell, Peter Liljeström and Caetano Reis e Sousa Nature433, 887–892
(24 February 2005); doi:10.1038/nature03326
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news and views Immunology: Guide for a cell-fate decision
Ellen A. Robey Nature433, 813–814
(24 February 2005); doi:10.1038/433813a
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article Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141
Peter Tomasec, Eddie C Y Wang, Andrew J Davison, Borivoj Vojtesek, Melanie Armstrong, Cora Griffin, Brian P McSharry, Rebecca J Morris, Sian Llewellyn-Lacey, Carole Rickards, Akio Nomoto, Christian Sinzger and Gavin W G Wilkinson Nature Immunology6, 181–188
(February 2005); doi:10.1038/ni1156
| Abstract | Full Text (HTML/PDF) |
review article Roles of interferon-regulatory factors in T-helper-cell differentiation
Michael Lohoff and Tak W. Mak Nature Reviews Immunology5, 125–135
(February 2005); doi:10.1038/nri1552
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article Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
Dongsheng Cai, Minsheng Yuan, Daniel F Frantz, Peter A Melendez, Lone Hansen, Jongsoon Lee and Steven E Shoelson Nature Medicine11, 183–190
(February 2005); doi:10.1038/nm1166
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article CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
Xuguang Tai, Michelle Cowan, Lionel Feigenbaum and Alfred Singer Nature Immunology6, 152–162
(February 2005); doi:10.1038/ni1160
| Abstract | Full Text (HTML/PDF) |
review article Close encounters of different kinds: Dendritic cells and NK cells take centre stage
Mariapia A. Degli-Esposti and Mark J. Smyth Nature Reviews Immunology5, 112–124
(February 2005); doi:10.1038/nri1549
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article Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function
Roman Spörri and Caetano Reis e Sousa Nature Immunology6, 163–170
(February 2005); doi:10.1038/ni1162
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news and views No driving without a license
William R Heath and Jose A Villadangos Nature Immunology6, 125–126
(February 2005); doi:10.1038/ni0205-125
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review article Host persistence: exploitation of anti-inflammatory pathways by Toxoplasma GONDII
Julio Aliberti Nature Reviews Immunology5, 162–170
(February 2005); doi:10.1038/nri1547
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letters to nature CD36 is a sensor of diacylglycerides
Kasper Hoebe, Philippe Georgel, Sophie Rutschmann, Xin Du, Suzanne Mudd, Karine Crozat, Sosathya Sovath, Louis Shamel, Thomas Hartung, Ulrich Zähringer and Bruce Beutler Nature433, 523–527
(03 February 2005); doi:10.1038/nature03253
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article Downregulation of lipopolysaccharide response in drosophila by negative crosstalk between the AP1 and NF-κB signaling modules
Taeil Kim, Joonsun Yoon, Hwansung Cho, Wook-bin Lee, Joon Kim, Young-Hwa Song, Se Nyun Kim, Jeong Ho Yoon, Jeongsil Kim-Ha and Young-Joon Kim Nature Immunology6, 211–218
(February 2005); doi:10.1038/ni1159
| Abstract | Full Text (HTML/PDF) |
review article Mast cells in the development of adaptive immune responses
Stephen J Galli, Susumu Nakae and Mindy Tsai Nature Immunology6, 135–142
(February 2005); doi:10.1038/ni1158
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review article The tetraspanin web modulates immune-signalling complexes
Shoshana Levy and Tsipi Shoham Nature Reviews Immunology5, 136–148
(February 2005); doi:10.1038/nri1548
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January
article Lethal anemia caused by interferon-β produced in mouse embryos carrying undigested DNA
Hideyuki Yoshida, Yasutaka Okabe, Kohki Kawane, Hidehiro Fukuyama and Shigekazu Nagata Nature Immunology6, 49–56
(January 2005); doi:10.1038/ni1146
| Abstract | Full Text (HTML/PDF) |
review article α-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles
Luc Van Kaer Nature Reviews Immunology5, 31–42
(January 2005); doi:10.1038/nri1531
| Summary | Full Text (HTML / PDF) |
news and views Inflammation and cancer: the long reach of Ras
Michael Karin Nature Medicine11, 20–21
(January 2005); doi:10.1038/nm0105-20
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article Viral modulation of NK cell immunity
Melissa B. Lodoen and Lewis L. Lanier Nature Reviews Microbiology3, 59–69
(January 2005); doi:10.1038/nrmicro1066
| Abstract | Full Text (HTML/PDF) |
news and views B-cell lymphoma: suppressing a tumor suppressor
Alexander Dent Nature Medicine11, 22
(January 2005); doi:10.1038/nm0105-22
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article Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1
Leslie L Sharp, Julie M Jameson, Gabrielle Cauvi and Wendy L Havran Nature Immunology6, 73–79
(January 2005); doi:10.1038/ni1152
| Abstract | Full Text (HTML/PDF) |
review article Immunoregulatory functions of surfactant proteins
Jo Rae Wright Nature Reviews Immunology5, 58–68
(January 2005); doi:10.1038/nri1528
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letter Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry
Micah T McClain, Latisha D Heinlen, Gregory J Dennis, Jon Roebuck, John B Harley and Judith A James Nature Medicine11, 85–89
(January 2005); doi:10.1038/nm1167
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review article LPS, TLR4 and infectious disease diversity
Samuel I. Miller, Robert K. Ernst and Martin W. Bader Nature Reviews Microbiology3, 36–46
(January 2005); doi:10.1038/nrmicro1068
| Abstract | Full Text (HTML/PDF) |
article B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
John R Sedy, Maya Gavrieli, Karen G Potter, Michelle A Hurchla, R Coleman Lindsley, Kai Hildner, Stefanie Scheu, Klaus Pfeffer, Carl F Ware, Theresa L Murphy and Kenneth M Murphy Nature Immunology6, 90–98
(January 2005); doi:10.1038/ni1144
| Abstract | Full Text (HTML/PDF) |
review article Protein tyrosine phosphatases and the immune response
Tomas Mustelin, Torkel Vang and Nunzio Bottini Nature Reviews Immunology5, 43–57
(January 2005); doi:10.1038/nri1530
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news and views Autoimmunity and apoptosis: refusing to go quietly
Donna L Bratton and Peter M Henson Nature Medicine11, 26–27
(January 2005); doi:10.1038/nm0105-26
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review article Galectins as modulators of tumour progression
Fu-Tong Liu and Gabriel A. Rabinovich Nature Reviews Cancer5, 29–41
(January 2005); doi:10.1038/nrc1527
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article Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes
Nami McCarty, Silke Paust, Koichi Ikizawa, Ippeita Dan, Xiaoyan Li and Harvey Cantor Nature Immunology6, 65–72
(January 2005); doi:10.1038/ni1145
| Abstract | Full Text (HTML/PDF) |
news and views Signaling negative selection: is MINK the missing link?
Ed Palmer Nature Immunology6, 9–10
(January 2005); doi:10.1038/ni0105-9
| Full Text (HTML/PDF) |
perspectives Innate and adaptive immunity: specificities and signaling hierarchies revisited
Eric Vivier and Bernard Malissen Nature Immunology6, 17–21
(January 2005); doi:10.1038/ni1153
| Abstract | Full Text (HTML/PDF) |
review article Psoriasis: emerging therapeutic strategies
Alice B. Gottlieb Nature Reviews Drug Discovery4, 19–34
(January 2005); doi:10.1038/nrd1607
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