letter Early events in the thymus affect the balance of effector and regulatory T cells
Daniel J. Pennington, Bruno Silva-Santos, Tobias Silberzahn, Mónica Escórcio-Correia, Martin J. Woodward, Scott J. Roberts, Adrian L. Smith, P. Julian Dyson and Adrian C. Hayday Nature444, 1073–1077
(21 December 2006); doi:10.1038/nature05368
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review Tuning inflammation and immunity by chemokine sequestration: decoys and more
Alberto Mantovani, Raffaella Bonecchi and Massimo Locati Nature Reviews Immunology7, 907–918
(December 2006); doi:10.1038/nri1964
| Summary | Full Text (HTML / PDF) |
review Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies
Robert E W Hancock & Hans-Georg Sahl Nature Biotechnology24, 1551–1557
(December 2006); doi:10.1038/nbt1267
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article Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism
Qing Chen, Daniel T Fisher, Kristen A Clancy, Jean-Marc M Gauguet, Wan-Chao Wang, Emily Unger, Stefan Rose-John, Ulrich H von Andrian, Heinz Baumann & Sharon S Evans Nature Immunology7, 1293–1298
(December 2006); doi:10.1038/ni1406
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article Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells
Karin Loser, Annette Mehling, Stefanie Loeser, Jenny Apelt, Annegret Kuhn, Stephan Grabbe, Thomas Schwarz, Josef M Penninger & Stefan Beissert Nature Medicine12, 1372–1379
(December 2006); doi:10.1038/nm1518
| Summary | Full Text (HTML / PDF) |
news and views Skin controls immune regulators
Tomoyuki Yamaguchi & Shimon Sakaguchi Nature Medicine12, 1358–1359
(December 2006); doi:10.1038/nm1206-1358
| Summary | Full Text (HTML / PDF) |
article Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling
Mark A. Daniels, Emma Teixeiro, Jason Gill, Barbara Hausmann, Dominique Roubaty, Kaisa Holmberg, Guy Werlen, Georg A. Holländer, Nicholas R. J. Gascoigne and Ed Palmer Nature444, 724–729
(7 December 2006); doi:10.1038/nature05269
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article Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
Jongdae Lee, Ji-Hun Mo, Kyoko Katakura, Irit Alkalay, Adam N. Rucker, Yu-Tsueng Liu, Hyun-Ku Lee, Carol Shen, Gady Cojocaru, Steve Shenouda, Martin Kagnoff, Lars Eckmann, Yinon Ben-Neriah & Eyal Raz Nature Cell Biology8, 1327–1336
(December 2006); doi:10.1038/ncb1500
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review Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitism
Ricardo T. Gazzinelli and Eric Y. Denkers Nature Reviews Immunology6, 895–906
(December 2006); doi:10.1038/nri1978
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review Genetics of autoimmune diseases — disorders of immune homeostasis
Peter K. Gregersen and Timothy W. Behrens Nature Reviews Genetics7, 917–928
(December 2006); doi:10.1038/nrg1944
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letter Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
Sachie Hiratsuka, Akira Watanabe, Hiroyuki Aburatani & Yoshiro Maru Nature Cell Biology8, 1369–1375
(December 2006); doi:10.1038/ncb1507
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news and views S100 chemokines mediate bookmarking of premetastatic niches
Shahin Rafii & David Lyden Nature Cell Biology8, 1321–1323
(December 2006); doi:10.1038/ncb1206-1321
| Summary | Full Text (HTML / PDF) |
article Control of thymocyte development and recombination-activating gene expression by the zinc finger protein Zfp608
Feng Zhang, Lance R Thomas, Eugene M Oltz & Thomas M Aune Nature Immunology7, 1309–1316
(December 2006); doi:10.1038/ni1397
| Summary | Full Text (HTML / PDF) |
news and views Fetal thymocyte development: putting a zinc finger on it?
Andrea C Carpenter & Craig H Bassing Nature Immunology7, 1285–1286
(December 2006); doi:10.1038/ni1206-1285
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article Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
Attila Mócsai, Clare L Abram, Zoltán Jakus, Yongmei Hu, Lewis L Lanier & Clifford A Lowell Nature Immunology7, 1326–1333
(December 2006); doi:10.1038/ni1407
| Summary | Full Text (HTML / PDF) |
news and views Integrins and ITAMs: more than just good neighbors
Mark L Kahn & Gary A Koretzky Nature Immunology7, 1286–1288
(December 2006); doi:10.1038/ni1206-1286
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review Perforin-mediated target-cell death and immune homeostasis
Ilia Voskoboinik, Mark J. Smyth and Joseph A. Trapani Nature Reviews Immunology6, 940–952
(December 2006); doi:10.1038/nri1983
| Summary | Full Text (HTML / PDF) |
review SNAREing immunity: the role of SNAREs in the immune system
Jennifer L. Stow, Anthony P. Manderson and Rachael Z. Murray Nature Reviews Immunology6, 919–929
(December 2006); doi:10.1038/nri1980
| Summary | Full Text (HTML / PDF) |
November
article Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression
Amiram Ariel, Gabrielle Fredman, Yee-Ping Sun, Alpdogan Kantarci, Thomas E Van Dyke, Andrew D Luster & Charles N Serhan Nature Immunology7, 1209–1216
(November 2006); doi:10.1038/ni1392
| Summary | Full Text (HTML / PDF) |
review Toll-like receptors in systemic autoimmune disease
Ann Marshak-Rothstein Nature Reviews Immunology6, 823–835
(November 2006); doi:10.1038/nri1957
| Summary | Full Text (HTML / PDF) |
article RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
Yi Gu, Hee-Don Chae, Jamie E Siefring, Aparna C Jasti, David A Hildeman & David A Williams Nature Immunology7, 1182–1190
(November 2006); doi:10.1038/ni1396
| Summary | Full Text (HTML / PDF) |
article A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance
Lequn Li, Yoshiko Iwamoto, Alla Berezovskaya & Vassiliki A Boussiotis Nature Immunology7, 1157–1165
(November 2006); doi:10.1038/ni1398
| Summary | Full Text (HTML / PDF) |
letter Spider toxins activate the capsaicin receptor to produce inflammatory pain
Jan Siemens, Sharleen Zhou, Rebecca Piskorowski, Tetsuro Nikai, Ellen A. Lumpkin, Allan I. Basbaum, David King and David Julius Nature444, 208–212
(09 November 2006); doi:10.1038/nature05285
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news and views Physiology: Channelled pain
Lesley Anson Nature444, 156
(09 November 2006); doi:10.1038/444156b
| Full Text (HTML / PDF) |
letter Structure of C3b reveals conformational changes that underlie complement activity
Bert J. C. Janssen, Agni Christodoulidou, Andrew McCarthy, John D. Lambris and Piet Gros Nature444, 213–216
(09 November 2006); doi:10.1038/nature05172
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letter Structure of C3b in complex with CRIg gives insights into regulation of complement activation
Christian Wiesmann, Kenneth J. Katschke, JianPing Yin, Karim Y. Helmy, Micah Steffek, Wayne J. Fairbrother, Scott A. McCallum, Lizette Embuscado, Laura DeForge, Philip E. Hass and Menno van Lookeren Campagne Nature444, 217–220
(09 November 2006); doi:10.1038/nature05263
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letter The structure of complement C3b provides insights into complement activation and regulation
A. Abdul Ajees , K. Gunasekaran , John E. Volanakis , Sthanam. V. L. Narayana , Girish J. Kotwal and H. M. Krishna Murthy Nature444, 221–225
(09 November 2006); doi:10.1038/nature05258
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news and views Immunology: Exposure of an executioner
Michael Carroll Nature444, 159–160
(09 November 2006); doi:10.1038/nature05307
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letter CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse
Regina Tavano, Rita Lucia Contento, Sonia Jimenez Baranda, Marzia Soligo, Loretta Tuosto, Santos Manes & Antonella Viola Nature Cell Biology8, 1270–1276
(November 2006); doi:10.1038/ncb1492
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article T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-α
Yuanyuan Zha, Reinhard Marks, Allen W Ho, Amy C Peterson, Sujit Janardhan, Ian Brown, Kesavannair Praveen, Stacey Stang, James C Stone & Thomas F Gajewski Nature Immunology7, 1166–1173
(November 2006); doi:10.1038/ni1394
| Summary | Full Text (HTML / PDF) |
article Disruption of diacylglycerol metabolism impairs the induction of T cell anergy
Benjamin A Olenchock, Rishu Guo, Jeffery H Carpenter, Martha Jordan, Matthew K Topham, Gary A Koretzky & Xiao-Ping Zhong Nature Immunology7, 1174–1181
(November 2006); doi:10.1038/ni1400
| Summary | Full Text (HTML / PDF) |
news and views Linking diacylglycerol kinase to T cell anergy
Daniel L Mueller Nature Immunology7, 1132–1134
(November 2006); doi:10.1038/ni1106-1132
| Summary | Full Text (HTML / PDF) |
article Interleukin-10 determines viral clearance or persistence in vivo
David G Brooks, Matthew J Trifilo, Kurt H Edelmann, Luc Teyton, Dorian B McGavern & Michael B A Oldstone Nature Medicine12, 1301–1309
(November 2006); doi:10.1038/nm1492
| Summary | Full Text (HTML / PDF) |
letter Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination
Jeoung-Sook Shin, Melanie Ebersold, Marc Pypaert, Lelia Delamarre, Adam Hartley and Ira Mellman Nature444 115–118
(02 November 2006); doi:10.1038/nature05261
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article Signals mediated by transforming growth factor-β initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
Marc Veldhoen, Richard J Hocking, Richard A Flavell & Brigitta Stockinger Nature Immunology7, 1151–1156
(November 2006); doi:10.1038/ni1391
| Summary | Full Text (HTML / PDF) |
review The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes
David J. Rawlings, Karen Sommer and Miguel E. Moreno-García Nature Reviews Immunology6, 799–812
(November 2006); doi:10.1038/nri1944
| Summary | Full Text (HTML / PDF) |
October
article Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity
Chongmin Huan, Matthew L Kelly, Ryan Steele, Iuliana Shapira, Susan R S Gottesman, Christopher A J Roman Nature Immunology7, 1082–1091
(2006); doi:10.1038/ni1378
| First Paragraph | Full Text (HTML / PDF) |
review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology6, 728–740
(October 2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
review Adipocytokines: mediators linking adipose tissue, inflammation and immunity
Herbert Tilg and Alexander R. Moschen Nature Reviews Immunology6, 772–783
(October 2006); doi:10.1038/nri1937
| Summary | Full Text (HTML / PDF) |
article Smad6 negatively regulates interleukin 1-receptor–Toll-like receptor signaling through direct interaction with the adaptor Pellino-1
Kyung-Chul Choi, Youn Sook Lee, Seunghwan Lim, Hyo Kyoung Choi, Chang-Hun Lee, Eun-Kyung Lee, Suntaek Hong, In-Hoo Kim, Seong-Jin Kim & Seok Hee Park Nature Immunology7, 1057–1065
(2006); doi:10.1038/ni1383
| Summary | Full Text (HTML / PDF) |
article Surface-bound chemokines capture and prime T cells for synapse formation
Rachel S Friedman, Jordan Jacobelli & Matthew F Krummel Nature Immunology7, 1101–1108
(2006); doi:10.1038/ni1384
| Summary | Full Text (HTML / PDF) |
review Reciprocal regulation between natural killer cells and autoreactive T cells
Fu-Dong Shi and Luc Van Kaer Nature Reviews Immunology6, 751–760
(2006); doi:10.1038/nri1935
| Summary | Full Text (HTML / PDF) |
article Decidual NK cells regulate key developmental processes at the human fetal-maternal interface
Jacob Hanna, Debra Goldman-Wohl, Yaron Hamani, Inbal Avraham, Caryn Greenfield, Shira Natanson-Yaron, Diana Prus, Leonor Cohen-Daniel, Tal I Arnon, Irit Manaster, Roi Gazit, Vladimir Yutkin, Daniel Benharroch, Angel Porgador, Eli Keshet, Simcha Yagel & Ofer Mandelboim Nature Medicine12, 1065–1074
( 2006); doi:10.1038/nm1452
| Summary | Full Text (HTML / PDF) |
article The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
Michael Carty, Rory Goodbody, Martina Schröder, Julianne Stack, Paul N Moynagh & Andrew G Bowie Nature Immunology7, 1074–1081
(2006); doi:10.1038/ni1382
| Summary | Full Text (HTML / PDF) |
news and views DisSARMing Toll-like receptor signaling
Luke A J O'Neill Nature Immunology7, 1023–1025
(2006); doi:10.1038/ni1006-1023
| Summary | Full Text (HTML / PDF) |
review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology7, 728–740
(2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
letter TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis
Carolyn G King, Takashi Kobayashi, Pedro J Cejas, Taesoo Kim, Kwiyeom Yoon, Gregory K Kim, Elise Chiffoleau, Somia P Hickman, Patrick T Walsh, Laurence A Turka & Yongwon Choi Nature Medicine12, 1088–1092
(2006); doi:10.1038/nm1449
| Summary | Full Text (HTML / PDF) |
article Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
Marina Scheller, Joerg Huelsken, Frank Rosenbauer, Makoto M Taketo, Walter Birchmeier, Daniel G Tenen & Achim Leutz Nature Immunology7, 1037–1047
(October 2006); doi:10.1038/ni1387
| Summary | Full Text (HTML / PDF) |
article Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
Peggy Kirstetter, Kristina Anderson, Bo T Porse, Sten Eirik W Jacobsen & Claus Nerlov Nature Immunology7, 1048–1056
(October 2006); doi:10.1038/ni1381
| Summary | Full Text (HTML / PDF) |
news and views Hematopoietic stem cell biology: too much of a Wnt thing
Jennifer J Trowbridge, Randall T Moon & Mickie Bhatia Nature Immunology7, 1021–1023
(October 2006); doi:10.1038/ni1006-1021
| Summary | Full Text (HTML / PDF) |
review Immunological mechanisms of allergen-specific immunotherapy
Mark Larché , Cezmi A. Akdis and Rudolf Valenta Nature Reviews Immunology6, 761–771
(October 2006); doi:10.1038/nri1934
| Summary | Full Text (HTML / PDF) |
article Lamin B1 duplications cause autosomal dominant leukodystrophy
Quasar S Padiath, Kazumasa Saigoh, Raphael Schiffmann, Hideaki Asahara, Takeshi Yamada, Anulf Koeppen, Kirk Hogan, Louis J Ptác caronek & Ying-Hui Fu Nature Genetics38, 1114–1123
(2006); doi:10.1038/ng1872
| Summary | Full Text (HTML / PDF) |
September
letter Centrosome polarization delivers secretory granules to the immunological synapse
Jane C. Stinchcombe, Endre Majorovits, Giovanna Bossi, Stephen Fuller and Gillian M. Griffiths Nature443, 462–465
(28 September 2006); doi:10.1038/nature05071
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review IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
Kenya Honda and Tadatsugu Taniguchi Nature Reviews Immunology6, 644–658
(September 2006); doi:10.1038/nri1900
| Summary | Full Text (HTML / PDF) |
article Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis
Adriano G Rossi, Deborah A Sawatzky, Annemieke Walker, Carol Ward, Tara A Sheldrake, Nicola A Riley, Alison Caldicott, Magdalena Martinez-Losa, Trevor R Walker, Rodger Duffin, Mohini Gray, Elvira Crescenzi, Morag C Martin, Hugh J Brady, John S Savill, Ian Dransfield & Christopher Haslett Nature Medicine12, 1056–1064
(September 2006); doi:10.1038/nm1468
| Summary | Full Text (HTML / PDF) |
letter TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis
Carolyn G King, Takashi Kobayashi, Pedro J Cejas, Taesoo Kim, Kwiyeom Yoon, Gregory K Kim, Elise Chiffoleau, Somia P Hickman, Patrick T Walsh, Laurence A Turka & Yongwon Choi Nature Medicine12, 1088–1092
(September 2006); doi:10.1038/nm1449
| Summary | Full Text (HTML / PDF) |
news and views Supressing the supressors
Pamela S Ohashi & Wen Chen Yeh Nature Medicine12, 1000–1002
(September 2006); doi:10.1038/nm0906-1000
| Summary | Full Text (HTML / PDF) |
article Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
Koko Katagiri, Masashi Imamura & Tatsuo Kinashi Nature Immunology7, 919–928
(September 2006); doi:10.1038/ni1374
| Summary |
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letter PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela, Julia A. Brown, Eshia S. Moodley, Sharon Reddy, Elizabeth W. Mackey, Joseph D. Miller, Alasdair J. Leslie, Chantal DePierres, Zenele Mncube, Jaikumar Duraiswamy, Baogong Zhu, Quentin Eichbaum, Marcus Altfeld, E. John Wherry, Hoosen M. Coovadia, Philip J. R. Goulder, Paul Klenerman, Rafi Ahmed, Gordon J. Freeman and Bruce D. Walker Nature443, 350–354
(21 September 2006); doi:10.1038/nature05115
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article Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice
Geert van Loo, Rossana De Lorenzi, Hauke Schmidt, Marion Huth, Alexander Mildner, Marc Schmidt-Supprian, Hans Lassmann, Marco R Prinz and Manolis Pasparakis Nature Immunology7, 954–961
(2006); doi:10.1038/ni1372
| Summary | Full Text (HTML / PDF) |
news and views At once harmful and beneficial: the dual properties of NF-κB
Sawsan Youssef & Lawrence Steinman Nature Immunology7, 901–902
(2006); doi:10.1038/ni0906-901
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article Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation
Johannes L Zakrzewski, Adam A Kochman, Sydney X Lu, Theis H Terwey, Theo D Kim, Vanessa M Hubbard, Stephanie J Muriglan, David Suh, Odette M Smith, Jeremy Grubin, Neel Patel, Andrew Chow, Javier Cabrera-Perez, Radhika Radhakrishnan, Adi Diab, Miguel-Angel Perales, Gabrielle Rizzuto, Ewa Menet, Eric G Pamer, Glen Heller, Juan Carlos Zúñiga-Pflücker, Õnder Alpdogan & Marcel R M van den Brink Nature Medicine12, 1039–1047
(2006); doi:10.1038/nm1463
| Summary | Full Text (HTML / PDF) |
article Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
Marcel Batten, Ji Li, Sothy Yi, Noelyn M Kljavin, Dimitry M Danilenko, Sophie Lucas, James Lee, Frederic J de Sauvage & Nico Ghilardi Nature Immunology7, 929–936
(13 August 2006); doi:10.1038/ni1375
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article Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Jason S Stumhofer, Arian Laurence, Emma H Wilson, Elaine Huang, Cristina M Tato, Leanne M Johnson, Alejandro V Villarino, Qiulong Huang, Akihiko Yoshimura, David Sehy, Christiaan J M Saris, John J O'Shea, Lothar Hennighausen, Matthias Ernst & Christopher A Hunter Nature Immunology7, 937–945
(13 August 2006); doi:10.1038/ni1376
| Summary | Full Text (HTML / PDF) |
news and views All in the family: IL-27 suppression of TH-17 cells
John Colgan & Paul Rothmanr Nature Immunology7, 899–901
(2006); doi:10.1038/ni0906-899
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article Mast cells are essential intermediaries in regulatory T-cell tolerance
Li-Fan Lu, Evan F. Lind, David C. Gondek, Kathy A. Bennett, Michael W. Gleeson, Karina Pino-Lagos, Zachary A. Scott, Anthony J. Coyle, Jennifer L. Reed, Jacques Van Snick, Terry B. Strom, Xin Xiao Zheng and Randolph J. Noelle Nature442, 997–1002
(31 August 2006); doi:10.1038/nature05010
| Summary | Full Text (HTML / PDF) |
news and views Immunology: Protection and privilege
Herman Waldmann Nature442, 987–988
(31 August 2006); doi:10.1038/nature05165
| Full Text (HTML / PDF) |
article Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
Masahiro Yamamoto, Toru Okamoto, Kiyoshi Takeda, Shintaro Sato, Hideki Sanjo, Satoshi Uematsu, Tatsuya Saitoh, Naoki Yamamoto, Hiroaki Sakurai, Ken J Ishii, Shoji Yamaoka, Taro Kawai, Yoshiharu Matsuura, Osamu Takeuchi & Shizuo Akirar Nature Immunology7, 962–970
(September 2006); doi:10.1038/ni1367
| Summary | Full Text (HTML / PDF) |
news and views E2 enzymes: expanding the 'ubi-verse' of immune signaling
Averil Ma & Emre Turer Nature Immunology7, 903–904
(September 2006); doi:10.1038/ni0906-903
| Summary | Full Text (HTML / PDF) |
August
article The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
Yisong Y Wan, Hongbo Chi, Min Xie, Michael D Schneider & Richard A Flavell Nature Immunology7, 851–858
(August 2006); doi:10.1038/ni1355
| Summary | Full Text (HTML / PDF) |
letter Connexin37 protects against atherosclerosis by regulating monocyte adhesion
Cindy W Wong, Thomas Christen, Isabelle Roth, Christos E Chadjichristos, Jean-Paul Derouette, Bernard F Foglia, Marc Chanson, Daniel A Goodenough & Brenda R Kwak Nature Medicine12, 950–954
(August 2006); doi:10.1038/nm1441
| Summary | Full Text (HTML / PDF) |
article Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs
Glen Pearce, Veronique Angeli, Gwendalyn J Randolph, Tobias Junt, Ulrich von Andrian, Hans-Joachim Schnittler & Rolf Jessberger Nature Immunology7, 827–834
(10 August 2006); doi:10.1038/ni1365
| Summary | Full Text (HTML / PDF) |
article Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
Olaf Gross, Andreas Gewies, Katrin Finger, Martin Schäfer, Tim Sparwasser, Christian Peschel, Irmgard Förster and Jürgen Ruland Nature442, 651–656
(10 August 2006); doi:10.1038/nature04926
| Summary | Full Text (HTML / PDF) |
letter SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production
Elena Friedmann, Ehud Hauben, Kerstin Maylandt, Simone Schleeger, Sarah Vreugde, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Daniela Stauffer, Giorgio Rovelli & Bruno Martoglio Nature Cell Biology8, 843–848
(10 August 2006); doi:10.1038/ncb1440
| First Paragraph | Full Text (HTML / PDF) |
article Herpes simplex virus evades natural killer T cell recognition by suppressing CD1d recycling
Weiming Yuan, Anindya Dasgupta & Peter Cresswell Nature Immunology7, 835–842
(August 2006); doi:10.1038/ni1364
| Summary | Full Text (HTML / PDF) |
news and views Viral evasion of antigen presentation: not just for peptides anymore
Luc Van Kaer & Sebastian Joyce Nature Immunology7, 795–797
(August 2006); doi:10.1038/ni0806-795
| Summary | Full Text (HTML / PDF) |
article Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling
Nagendra Singh, Yoichi Seki, Mariko Takami, Babak Baban, Phil R Chandler, Davood Khosravi, Xiangjian Zheng, Mayuko Takezaki, Jeffrey R Lee, Andrew L Mellor, Wendy B Bollag & Makio Iwashima Nature Methods3, 629–636
(August 2006); doi:10.1038/nmeth903
| Summary | Full Text (HTML / PDF) |
article Foxp1 is an essential transcriptional regulator of B cell development
Hui Hu, Bin Wang, Madhuri Borde, Julie Nardone, Shan Maika, Laura Allred, Philip W Tucker & Anjana Rao Nature Immunology7, 819–826
(August 2006); doi:10.1038/ni1358
| Summary | Full Text (HTML / PDF) |
news and views FOXtrot and RAGtime in B cells
Fabio Savarese & Rudolf Grosschedl Nature Immunology7, 793–794
(August 2006); doi:10.1038/ni0806-793
| Summary | Full Text (HTML / PDF) |
review The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design
Thomas A. Waldmann Nature Reviews Immunology6, 595–601
(August 2006); doi:10.1038/nri1901
| Summary | Full Text (HTML / PDF) |
review Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
Alexander J. Muller and Peggy A. Scherle Nature Reviews Cancer6, 613–625
(August 2006); doi:10.1038/nrc1929
| Summary | Full Text (HTML / PDF) |
July
letter IL-23 promotes tumour incidence and growth
John L. Langowski, Xueqing Zhang, Lingling Wu, Jeanine D. Mattson, Taiying Chen, Kathy Smith, Beth Basham, Terrill McClanahan, Robert A. Kastelein and Martin Oft Nature442, 461–465
(27 July 2006); doi:10.1038/nature04808
| First Paragraph | Full Text (HTML / PDF) |
article Neutrophil direction sensing and superoxide production linked by the GTPase-activating protein GIT2
Yuichi Mazaki, Shigeru Hashimoto, Tohru Tsujimura, Masaki Morishige, Ari Hashimoto, Kosuke Aritake, Atsuko Yamada, Jin-Min Nam, Hiroshi Kiyonari, Kazuki Nakao & Hisataka Sabe Nature Immunology7, 724–731
(June 2006); doi:10.1038/ni1349
| Summary | Full Text (HTML / PDF) |
article Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases
Anouk Caraux, Qingxian Lu, Nadine Fernandez, Sylvain Riou, James P Di Santo, David H Raulet, Greg Lemke & Claude Roth Nature Immunology7, 747–754
(June 2006); doi:10.1038/ni1353
| Summary | Full Text (HTML / PDF) |
news and views NK cell development: Gas matters
Thierry Walzer & Eric Vivier Nature Immunology7, 702–704
(July 2006); doi:10.1038/ni0706-702
| Summary | Full Text (HTML / PDF) |
article Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation
Seiichi Kuwajima, Taku Sato, Kazuto Ishida, Hiroyuki Tada, Hiroyuki Tezuka & Toshiaki Ohteki Nature Immunology7, 740–746
(July 2006); doi:10.1038/ni1348
| Summary | Full Text (HTML / PDF) |
news and views Division of labor and cooperation between dendritic cells
Bali Pulendran Nature Immunology7, 699–700
(July 2006); doi:10.1038/ni0706-699
| Summary | Full Text (HTML / PDF) |
review Neutrophil serine proteases: specific regulators of inflammation
Christine T. N. Pham Nature Reviews Immunology6, 541–550
(July 2006); doi:10.1038/nri1841
| Summary | Full Text (HTML / PDF) |
review Targeting signal transduction as a strategy to treat inflammatory diseases
Luke A. J. O'Neill Nature Reviews Drug Discovery7, 549–563
(July 2006); doi:10.1038/nrd2070
| Summary | Full Text (HTML / PDF) |
article Fas ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
Veronika Groh, Kimberly Smythe, Zhenpeng Dai & Thomas Spies Nature Immunology7, 755–762
(28 May 2006); doi:10.1038/ni1350
| First Paragraph | Full Text (HTML / PDF) |
review The many paths to p38 mitogen-activated protein kinase activation in the immune system
Jonathan D. Ashwell Nature Reviews Immunology6, 532–540
(July 2006); doi:10.1038/nri1865
| Summary | Full Text (HTML / PDF) |
review Intracellular pattern recognition receptors in the host response
Etienne Meylan, Jürg Tschopp and Michael Karin Nature442, 39–44
(06 July 2006); doi:10.1038/nature04946
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article Regulation of naive T cell function by the NF-κB2 pathway
Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi & Jonathan Sprent Nature Immunology7, 763–772
(July 2006); doi:10.1038/ni1351
| Summary | Full Text (HTML / PDF) |
June
article ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses
Stamatia Papoutsopoulou, Antony Symons, Tharsana Tharmalingham, Monica P Belich, Frank Kaiser, Dimitris Kioussis, Anne O'Garra, Victor Tybulewicz & Steven C Ley Nature Immunology7, 606 - 615
(June 2006); doi:10.1038/ni1334
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review article CEACAM1: contact-dependent control of immunity
Scott D. Gray-Owen and Richard S. Blumberg Nature Reviews Immunology6, 433–446
(June 2006); doi:10.1038/nri1864
| Summary | Full Text (HTML / PDF) |
article Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
Mihai G Netea, Leo A B Joosten, Eli Lewis, Dalan R Jensen, Peter J Voshol, Bart Jan Kullberg, Cees J Tack, Han van Krieken, Soo-Hyun Kim, Anton F Stalenhoef, Fons A van de Loo, Ineke Verschueren, Leslie Pulawa, Shizuo Akira, Robert H Eckel, Charles A Dinarello, Wim van den Berg & Jos W M van der Meer Nature Medicine12, 650 - 656
(June 2006); doi:10.1038/nm1415
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review article Therapeutic potential of Toll-like receptor 9 activation
Arthur M. Krieg Nature Reviews Drug Discovery5, 471–484
(June 2006); doi:10.1038/nrd2059
| Summary | Full Text (HTML / PDF) |
news and views TGF-ß, a 'double agent' in the immune pathology war
Daniel J Cua & Robert A Kastelein Nature Immunology7, 557 - 559
(June 2006); doi:10.1038/ni0606-557
| Summary | Full Text (HTML / PDF) |
letter Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
Simona W. Rossi, William E. Jenkinson, Graham Anderson and Eric J. Jenkinson Nature441, 988–991
(22 June 2006); doi:10.1038/nature04813
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letter Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis
Noriko Takegahara, Hyota Takamatsu, Toshihiko Toyofuku, Tohru Tsujimura, Tatsusada Okuno, Kazunori Yukawa, Masayuki Mizui, Midori Yamamoto, Durbaka V.R. Prasad, Kazuhiro Suzuki, Masaru Ishii, Kenta Terai, Masayuki Moriya, Yuji Nakatsuji, Saburo Sakoda, Shintaro Sato, Shizuo Akira, Kiyoshi Takeda, Masanori Inui, Toshiyuki Takai, Masahito Ikawa, Masaru Okabe, Atsushi Kumanogoh & Hitoshi Kikutani Nature Cell Biology8, 615 - 622
(June 2006); doi:10.1038/ncb1416
| Summary | Full Text (HTML / PDF) |
news and views Semaphorin pathways orchestrate osteogenesis
Luca Tamagnone & Silvia Giordano Nature Cell Biology8, 545 - 547
(June 2006); doi:10.1038/ncb0606-545
| Summary | Full Text (HTML / PDF) |
letter Generation of C5a in the absence of C3: a new complement activation pathway
Markus Huber-Lang, J Vidya Sarma, Firas S Zetoune, Daniel Rittirsch, Thomas A Neff, Stephanie R McGuire, John D Lambris, Roscoe L Warner, Michael A Flierl, Laszlo M Hoesel, Florian Gebhard, John G Younger, Scott M Drouin, Rick A Wetsel & Peter A Ward Nature Medicine12, 682 - 687
(June 2006); doi:10.1038/nm1419
| Summary | Full Text (HTML / PDF) |
letter Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
Matthew A. Williams, Aaron J. Tyznik and Michael J. Bevan Nature441, 890–893
(15 June 2006); doi:10.1038/nature04790
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article Quantitative proteomic analysis of B cell lipid rafts reveals that ezrin regulates antigen receptor-mediated lipid raft dynamics
Neetu Gupta, Bernd Wollscheid, Julian D Watts, Barbara Scheer, Ruedi Aebersold & Anthony L DeFranco Nature Immunology7, 625–633
(June 2006); doi:10.1038/ni1337
| First Paragraph | Full Text (HTML / PDF) |
article Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
Yuqin Yin, Michael T Henzl, Barbara Lorber, Toru Nakazawa, Tommy T Thomas, Fan Jiang, Robert Langer & Larry I Benowitz Nature Neuroscience9, 843–852
(June 2006); doi:10.1038/nn1701
| First Paragraph | Full Text (HTML / PDF) |
news and views How inflammation promotes regeneration
Marie T Filbin Nature Neuroscience9, 715–717
(June 2006); doi:10.1038/nn0606-715
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article Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1ß via Ipaf
Edward A Miao, Celia M Alpuche-Aranda, Monica Dors, April E Clark, Martin W Bader, Samuel I Miller and Alan Aderem Nature Immunology7, 569–575
(June 2006); doi:10.1038/ni1344
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article Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1ß in salmonella-infected macrophages
Luigi Franchi, Amal Amer, Mathilde Body-Malapel, Thirumala-Devi Kanneganti, Nesrin Özören, Rajesh Jagirdar, Naohiro Inohara, Peter Vandenabeele, John Bertin, Anthony Coyle, Ethan P Grant and Gabriel Núñez Nature Immunology7, 576–582
(June 2006); doi:10.1038/ni1346
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article Lysophospholipid sensing triggers secretion of flagellin from pathogenic salmonella
Naeha Subramanian and Ayub Qadri Nature Immunology7, 583–589
(June 2006); doi:10.1038/ni1336
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news and views Cytosolic detection of flagellin: a deadly twist
Craig R Roy and Dario S Zamboni Nature Immunology7, 549–551
(08 June 2006); doi:10.1038/ni0606-549
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review article The SIRP family of receptors and immune regulation
A. Neil Barclay and Marion H. Brown
(June 2006); doi:10.1038/nri1859
| Summary | Full Text (HTML / PDF) |
article Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
Tatsuya Saitoh, Adrian Tun-Kyi, Akihide Ryo, Masahiro Yamamoto, Greg Finn, Takashi Fujita, Shizuo Akira, Naoki Yamamoto, Kun Ping Lu & Shoji Yamaoka Nature Immunology7, 598–605
(June 2006); doi:10.1038/ni1347
| Summary | Full Text (HTML / PDF) |
news and views Pin-ning down immune responses to RNA viruses
Nadege Goutagny, Martina Severa & Katherine A Fitzgerald Nature Immunology7, 555–557
(June 2006); doi:10.1038/ni0606-555
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review article Defensins in innate antiviral immunity
Mary E. Klotman and Theresa L. Chang Nature Reviews Immunology6, 447–456
(June 2006); doi:10.1038/nri1860
| Summary | Full Text (HTML / PDF) |
brief communication Mutations in the gene encoding the PML nuclear body protein Sp110 are associated with immunodeficiency and hepatic veno-occlusive disease
Tony Roscioli, Simon T Cliffe, Donald B Bloch, Christopher G Bell, Glenda Mullan, Peter J Taylor, Maria Sarris, Joanne Wang, Jennifer A Donald, Edwin P Kirk, John B Ziegler, Ulrich Salzer, George B McDonald, Melanie Wong, Robert Lindeman & Michael F Buckley Nature Genetics38, 620–622
(June 2006); doi:10.1038/ng1780
| Summary | Full Text (HTML / PDF) |
May
article Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
Roi Gazit, Raizy Gruda, Moran Elboim, Tal I Arnon, Gil Katz, Hagit Achdout, Jacob Hanna, Udi Qimron, Guy Landau, Evgenia Greenbaum, Zichria Zakay-Rones, Angel Porgador & Ofer Mandelboim Nature Immunology7, 517–523
(May 2006); doi:10.1038/ni1322
| Summary | Full Text (HTML / PDF) |
news and views Natural cytotoxicity receptors: influenza virus in the spotlight
Thomas Spies & Veronika Groh Nature Immunology7, 443–444
(May 2006); doi:10.1038/ni0506-443
| Summary | Full Text (HTML / PDF) |
article A unique function for cyclin D3 in early B cell development
A Byron Cooper, Catherine M Sawai, Ewa Sicinska, Sarah E Powers, Piotr Sicinski, Marcus R Clark, Iannis Aifantis Nature Immunology7, 489–497
(May 2006); doi:10.1038/ni1324
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article Systems biology approaches identify ATF3 as a negative regulator of Toll–like receptor 4
Mark Gilchrist, Vesteinn Thorsson, Bin Li, Alistair G. Rust, Martin Korb, Kathleen Kennedy, Tsonwin Hai, Hamid Bolouri and Alan Aderem Nature441, 173–178
(11 May 2006); doi:10.1038/nature04768
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letter Transforming growth factor–ß induces development of the TH17 lineage
Paul R. Mangan, Laurie E. Harrington, Darrell B. O'Quinn, Whitney S. Helms, Daniel C. Bullard, Charles O. Elson, Robin D. Hatton, Sharon M. Wahl, Trenton R. Schoeb and Casey T. Weaver Nature441, 231–234
(11 May 2006); doi:10.1038/nature04754
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letter Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
Estelle Bettelli, Yijun Carrier, Wenda Gao, Thomas Korn, Terry B. Strom, Mohamed Oukka, Howard L. Weiner and Vijay K. Kuchroo Nature441, 235–238
(11 May 2006); doi:10.1038/nature04753
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news and views Immunology: What does it mean to be just 17?
Cristina M. Tato and John J. O'Shea Nature441, 166–168
(11 May 2006); doi:10.1038/441166a
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article NKG2D–mediated signaling requires a DAP10–bound Grb2–Vav1 intermediate and phosphatidylinositol–3–kinase in human natural killer cells
Jadee L Upshaw, Laura N Arneson, Renee A Schoon, Christopher J Dick, Daniel D Billadeau & Paul J Leibson Nature Immunology7, 524–532
(May 2006); doi:10.1038/ni1325
| Summary | Full Text (HTML / PDF) |
letter Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro
Marjorie A Robbins, Mingjie Li, Irene Leung, Haitang Li, Doris V Boyer, Yong Song, Mark A Behlke & John J Rossi Nature Biotechnology24, 566–571
(May 2006); doi:10.1038/nbt1206
| Summary | Full Text (HTML / PDF) |
news and views RNA interference below the immune radar
Mouldy Sioud Nature Biotechnology24, 521–522
(May 2006); doi:10.1038/nbt0506–521
| Summary | Full Text (HTML / PDF) |
review article MIF: a new cytokine link between rheumatoid arthritis and atherosclerosis
Eric F. Morand, Michelle Leech and Jürgen Bernhagen Nature Reviews Drug Discovery5, 399–411
(May 2006); doi:10.1038/nrd2029
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article Transcriptional repressor Blimp-1 regulates T cell homeostasis and function
Gislâine A Martins, Luisa Cimmino, Miriam Shapiro-Shelef, Matthias Szabolcs, Alan Herron, Erna Magnusdottir & Kathryn Calame Nature Immunology7, 457–465
(May 2006) | doi:10.1038/ni1321
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article Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
Axel Kallies, Edwin D Hawkins, Gabrielle T Belz, Donald Metcalf, Mirja Hommel, Lynn M Corcoran, Philip D Hodgkin & Stephen L Nutt Nature Immunology7, 466–474
(May 2006) | doi:10.1038/ni1321
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news and views T cells join the Blimp-1 brigade
Pamela J Fink Nature Immunology7, 445–446
(May 2006) | doi:10.1038/ni0506-445
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article Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells
Mari L Shinohara, Linrong Lu, Jing Bu, Miriam B F Werneck, Koichi S Kobayashi, Laurie H Glimcher & Harvey Cantor Nature Immunology7, 498–506
(May 2006) doi:10.1038/ni1327
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April
letter Targeting C-reactive protein for the treatment of cardiovascular disease
Mark B. Pepys, Gideon M. Hirschfield, Glenys A. Tennent, J. Ruth Gallimore, Melvyn C. Kahan, Vittorio Bellotti, Philip N. Hawkins, Rebecca M. Myers, Martin D. Smith, Alessandra Polara, Alexander J. A. Cobb, Steven V. Ley, J. Andrew Aquilina, Carol V. Robinson, Isam Sharif, Gillian A. Gray, Caroline A. Sabin, Michelle C. Jenvey, Simon E. Kolstoe, Darren Thompson and Stephen P. Wood Nature440, 1217–1221
(27 April 2006); doi:10.1038/nature04672
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review See no evil, hear no evil, do no evil: the lessons of immune privilege
Jerry Y Niederkorn Nature Immunology7, 354–359
(April 2006); doi:10.1038/ni1328
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review article Regulatory T cells, tumour immunity and immunotherapy
Weiping Zou Nature Reviews Immunology6, 295–307
(April 2006); doi:10.1038/nri1806
| Summary | Full Text (HTML / PDF) |
letter Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
Maya Saleh, John C. Mathison, Melissa K. Wolinski, Steve J. Bensinger, Patrick Fitzgerald, Nathalie Droin, Richard J. Ulevitch, Douglas R. Green and Donald W. Nicholson Nature440, 1064–1068
(20 April 2006); doi:10.1038/nature04656
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article Early hematopoietic lineage restrictions directed by Ikaros
Toshimi Yoshida, Samuel Yao-Ming Ng, Juan Carlos Zuniga-Pflucker & Katia Georgopoulos Nature Immunology7, 382–391
(April 2006); doi:10.1038/ni1314
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news and views Hematopoiesis flies high with Ikaros
Stephen T Smale & Kenneth Dorshkind Nature Immunology7, 367–369
(April 2006); doi:10.1038/ni0406-367
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review article Caspases at the crossroads of immune-cell life and death
Richard M. Siegel Nature Reviews Immunology6, 308–317
(April 2006); doi:10.1038/nri1809
| Summary | Full Text (HTML / PDF) |
article Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants
Thorbald van Hall, Elisabeth Z Wolpert, Peter van Veelen, Sandra Laban, Michael van der Veer, Marjet Roseboom, Sandra Bres, Per Grufman, Arnoud de Ru, Hugo Meiring, Ad de Jong, Kees Franken, Antoinette Teixeira, Rob Valentijn, Jan Wouter Drijfhout, Frits Koning, Marcel Camps, Ferry Ossendorp, Klas Kärre, Hans-Gustaf Ljunggren, Cornelis J M Melief & Rienk Offringa Nature Medicine12, 417–424
(April 2006); doi:10.1038/nm1381
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article Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction
Flora Castellino , Alex Y. Huang, Grégoire Altan-Bonnet, Sabine Stoll, Clemens Scheinecker and Ronald N. Germain Nature440, 890–895
(13 April 2006); doi:10.1038/nature04651
| Summary | Full Text (HTML / PDF) |
letter IkB kinase-a is critical for interferon-α production induced by Toll-like receptors 7 and 9
Katsuaki Hoshino, Takahiro Sugiyama, Mitsuru Matsumoto, Takashi Tanaka, Masuyoshi Saito, Hiroaki Hemmi, Osamu Ohara, Shizuo Akira and Tsuneyasu Kaisho Nature440, 949–953
(13 April 2006); doi:10.1038/nature04641
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article MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
Dongxu Sun & Aihao Ding Nature Immunology7, 375–381
(April 2006); doi:10.1038/ni1308
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news and views MyD88 beyond Toll
Jiahuai Han Nature Immunology7, 370–371
(April 2006); doi:10.1038/ni0406-370
| First Paragraph
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review article ITAM-mediated tonic signalling through pre-BCR and BCR complexes
John G. Monroe Nature Reviews Immunology4, 265–275
(April 2006); doi:10.1038/nri1808
| Summary | Full Text (HTML / PDF) |
March
review article Evolving knowledge and therapy of inflammatory bowel disease
Joshua R. Korzenik and Daniel K. Podolsky Nature Reviews Drug Discovery5, 197–209
(March 2006); doi:10.1038/nrd1986
| Summary | Full Text (HTML / PDF) |
review article CATERPILLERs, pyrin and hereditary immunological disorders
Jenny P.-Y. Ting, Daniel L. Kastner and Hal M. Hoffman Nature Reviews Immunology6, 183–195
(March 2006); doi:10.1038/nri1788
| Summary | Full Text (HTML / PDF) |
letter Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent
Fabiana S Machado, James E Johndrow, Lisia Esper, Alexandra Dias, Andre Bafica, Charles N Serhan & Julio Aliberti Nature Medicine12, 330–334
(March 2006); doi:10.1038/nm1355
| Summary | Full Text (HTML / PDF) |
Evolving knowledge and therapy of inflammatory bowel disease
Joshua R. Korzenik and Daniel K. Podolsky Nature Reviews Drug Discovery5, 197–209
(March 2006); doi:10.1038/nrd1986
| Summary | Full Text (HTML / PDF) |
letter CD69 acts downstream of interferon- α/ß to inhibit S1P1 and lymphocyte egress from lymphoid organs
Lawrence R. Shiow , David B. Rosen, Nadêzda Brdicková, Ying Xu, Jinping An, Lewis L. Lanier, Jason G. Cyster and Mehrdad Matloubian Nature440, 540–544
(23 March 2006); doi:10.1038/nature04606
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article Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
Natalya V Serbina and Eric G Pamer Nature Immunology7, 311–317
(March 2006); doi:10.1038/ni1309
| Abstract | Full Text (HTML/PDF) |
article Particularities of the vasculature can promote the organ specificity of autoimmune attack
Bryce A Binstadt, Pratik R Patel, Herlen Alencar, Peter A Nigrovic, David M Lee, Umar Mahmood, Ralph Weissleder, Diane Mathis and Christophe Benoist Nature Immunology7, 284–292
(March 2006); doi:10.1038/ni1306
| Abstract | Full Text (HTML/PDF) |
review article cFLIP regulation of lymphocyte activation and development
Ralph C. Budd, Wen-Chen Yeh and Jürg Tschopp Nature Reviews Immunology6, 196–204
(March 2006); doi:10.1038/nri1787
| Summary | Full Text (HTML / PDF) |
article A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
Nathaniel M Weathington, Anneke H van Houwelingen, Brett D Noerager, Patricia L Jackson, Aletta D Kraneveld, F Shawn Galin, Gert Folkerts, Frans P Nijkamp and J Edwin Blalock Nature Medicine12, 317–323
(March 2006); doi:10.1038/nm1361
| Abstract | Full Text (HTML/PDF) |
news and views The matrix degrades, neutrophils invade
Peter M Henson, R William Vandivier
Nature Medicine12, 280–281
(2006); doi:10.1038/nm0306-280
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review article An APRIL to remember: novel TNF ligands as therapeutic targets
Stacey R. Dillon, Jane A. Gross, Stephen M. Ansell and Anne J. Novak Nature Reviews Drug Discovery5, 235–246
(March 2006); doi:10.1038/nrd1982
| Summary | Full Text (HTML / PDF) |
article Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1
Kate L Jeffrey, Tilman Brummer, Michael S Rolph, Sue M Liu, Nuria A Callejas, Raelene J Grumont, Corine Gillieron, Fabienne Mackay, Shane Grey, Montserrat Camps, Christian Rommel, Steve D Gerondakis and Charles R Mackay Nature Immunology7, 274–283
(March 2006); doi:10.1038/ni1310
| Abstract | Full Text (HTML/PDF) |
review article Integrated signalling pathways for mast-cell activation
Alasdair M. Gilfillan and Christine Tkaczyk Nature Reviews Immunology6, 218–230
(March 2006); doi:10.1038/nri1782
| Abstract | Full Text (HTML/PDF) |
letter Cryopyrin activates the inflammasome in response to toxins and ATP
Sanjeev Mariathasan, David S. Weiss, Kim Newton, Jacqueline McBride, Karen O'Rourke, Meron Roose-Girma, Wyne P. Lee, Yvette Weinrauch, Denise M. Monack and Vishva M. Dixit Nature440, 228–232
(09 March 2006); doi:10.1038/nature04515
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letter Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
Thirumala-Devi Kanneganti, Nesrin Özören, Mathilde Body-Malapel, Amal Amer, Jong-Hwan Park, Luigi Franchi, Joel Whitfield, Winfried Barchet, Marco Colonna, Peter Vandenabeele, John Bertin, Anthony Coyle, Ethan P. Grant, Shizuo Akira and Gabriel Núñez Nature440, 233–236
(09 March 2006); doi:10.1038/nature04517
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letter Gout-associated uric acid crystals activate the NALP3 inflammasome
Fabio Martinon, Virginie Pétrilli, Annick Mayor, Aubry Tardivel and Jürg Tschopp Nature440, 237–241
(09 March 2006); doi:10.1038/nature04516
| First Paragraph | Full Text (HTML / PDF) |
letter How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP
Agnidipta Ghosh, Gerrit J. K. Praefcke, Louis Renault, Alfred Wittinghofer and Christian Herrmann Nature440, 101–104
(02 March 2006); doi:10.1038/nature04510
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article T cells use two directionally distinct pathways for cytokine secretion
Morgan Huse, Björn F Lillemeier, Michael S Kuhns, Daniel S Chen and Mark M Davis Nature Immunology7, 247–255
(March 2006); doi:10.1038/ni1304
| Abstract | Full Text (HTML/PDF) |
February
article Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
Yaya Wang, Yawei Tang, Lin Teng, Yalan Wu, Xiaohui Zhao and Gang Pei Nature Immunology7, 139–147
(February 2006); doi:10.1038/ni1294
| Abstract | Full Text (HTML/PDF) |
article Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling
Brian E Collins, Brian A Smith, Per Bengtson and James C Paulson Nature Immunology7, 199–206
(February 2006); doi:10.1038/ni1283
| Abstract | Full Text (HTML/PDF) |
article Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma
Stephan Mathas, Martin Janz, Franziska Hummel, Michael Hummel, Brigitte Wollert-Wulf, Simone Lusatis, Ioannis Anagnostopoulos, Andreas Lietz, Mikael Sigvardsson, Franziska Jundt, Korinna Jöhrens, Kurt Bommert, Harald Stein and Bernd Dörken Nature Immunology7, 207–215
(February 2006); doi:10.1038/ni1285
| Abstract | Full Text (HTML/PDF) |
article Control of human immunodeficiency virus replication by cytotoxic T lymphocytes targeting subdominant epitopes
Nicole Frahm, Photini Kiepiela, Sharon Adams, Caitlyn H Linde, Hannah S Hewitt, Kaori Sango, Margaret E Feeney, Marylyn M Addo, Mathias Lichterfeld, Matthew P Lahaie, Eunice Pae, Alysse G Wurcel, Timothy Roach, M Anne St John, Marcus Altfeld, Francesco M Marincola, Corey Moore, Simon Mallal, Mary Carrington, David Heckerman, Todd M Allen, James I Mullins, Bette T Korber, Philip J R Goulder, Bruce D Walker and Christian Brander Nature Immunology7, 173–178
(February 2006); doi:10.1038/ni1281
| Abstract | Full Text (HTML/PDF) |
article Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope
Astrid K N Iversen, Guillaume Stewart-Jones, Gerald H Learn, Natasha Christie, Christina Sylvester-Hviid, Andrew E Armitage, Rupert Kaul, Tara Beattie, Jean K Lee, Yanping Li, Pojchong Chotiyarnwong, Tao Dong, Xiaoning Xu, Mark A Luscher, Kelly MacDonald, Henrik Ullum, Bente Klarlund-Pedersen, Peter Skinhøj, Lars Fugger, Søren Buus, James I Mullins, E Yvonne Jones, P Anton van der Merwe and Andrew J McMichael Nature Immunology7, 179–189
(February 2006); doi:10.1038/ni1298
| Abstract | Full Text (HTML/PDF) |
news and views Crosscurrents in HIV-1 evolution
Joel N Blankson, Justin R Bailey and Robert F Siliciano Nature Immunology7, 121–122
(February 2006); doi:10.1038/ni0206-121
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article Restoring function in exhausted CD8 T cells during chronic viral infection
Daniel L. Barber, E. John Wherry, David Masopust, Baogong Zhu, James P. Allison, Arlene H. Sharpe, Gordon J. Freeman and Rafi Ahmed Nature439, 682–687
(09 February 2006); doi:10.1038/nature04444
| Summary | Full Text (HTML / PDF) |
news and views Immunology: Exhausted T cells perk up
Matthew A. Williams and Michael J. Bevan Nature439, 669–670
(09 February 2006); doi:10.1038/439669a
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letter Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection
Koert J. Stittelaar, Johan Neyts, Lieve Naesens, Geert van Amerongen, Rob F. van Lavieren, Antonin Holý, Erik De Clercq, Hubert G. M. Niesters, Edwin Fries, Chantal Maas, Paul G. H. Mulder, Ben A. M. van der Zeijst and Albert D. M. E. Osterhaus Nature439, 745–748
(09 February 2006); doi:10.1038/nature04295
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article Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity
Nicholas S Wilson, Georg M N Behrens, Rachel J Lundie, Christopher M Smith, Jason Waithman, Louise Young, Simon P Forehan, Adele Mount, Raymond J Steptoe, Ken D Shortman, Tania F de Koning-Ward, Gabrielle T Belz, Francis R Carbone, Brendan S Crabb, William R Heath and Jose A Villadangos Nature Immunology7, 165–172
(February 2006); doi:10.1038/ni1300
| Abstract | Full Text (HTML/PDF) |
news and views Youth has its privileges: maturation inhibits DC cross-priming
Heather D Hickman-Miller and Jonathan W Yewdell Nature Immunology7, 125–126
(February 2006); doi:10.1038/ni0206-125
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review article Journey through the thymus: stromal guides for T-cell development and selection
Yousuke Takahama Nature Reviews Immunology6, 127–135
(February 2006); doi:10.1038/nri1781
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letter Angiopoietin-2 sensitizes endothelial cells to TNF-α and has a crucial role in the induction of inflammation
Ulrike Fiedler, Yvonne Reiss, Marion Scharpfenecker, Verena Grunow, Stefanie Koidl, Gavin Thurston, Nicholas W Gale, Martin Witzenrath, Simone Rosseau, Norbert Suttorp, Astrid Sobke, Matthias Herrmann, Klaus T Preissner, Peter Vajkoczy and Hellmut G Augustin Nature Medicine12, 235–239
(March 2006); doi:10.1038/nm1351
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news and views Angiogenesis and inflammation face off
Beat A Imhof and Michel Aurrand-Lions Nature Medicine12, 171–172
(February 2006); doi:10.1038/nm0206-171
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article Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
Ashley Mansell, Rosealee Smith, Sarah L Doyle, Pearl Gray, Jennifer E Fenner, Peter J Crack, Sandra E Nicholson, Douglas J Hilton, Luke A J O'Neill and Paul J Hertzog Nature Immunology7, 148–155
(February 2006); doi:10.1038/ni1299
| Abstract | Full Text (HTML/PDF) |
news and views Mal-function of TLRs by SOCS
Takashi Kobayashi, Giichi Takaesu and Akihiko Yoshimura Nature Immunology7, 123–124
(February 2006); doi:10.1038/ni0206-123
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January
article Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57
Natalio Garbi, Satoshi Tanaka, Frank Momburg and Günter J Hämmerling Nature Immunology7, 93–102
(January 2006); doi:10.1038/ni1288
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article The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
Gianna Elena Hammer, Federico Gonzalez, Marine Champsaur, Dragana Cado and Nilabh Shastri Nature Immunology7, 103–112
(January 2006); doi:10.1038/ni1286
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news and views The 'chop-and-change' of MHC class I assembly
Tim Elliott Nature Immunology7, 7–9
(January 2006); doi:10.1038/ni0106-7
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review article Signalling pathways and molecular interactions of NOD1 and NOD2
Warren Strober, Peter J. Murray, Atsushi Kitani and Tomohiro Watanabe Nature Reviews Immunology6, 9–20
(January 2006); doi:10.1038/nri1747
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article Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex
Margaret D Myers, Tomasz Sosinowski, Leonard L Dragone, Carmen White, Hamid Band, Hua Gu and Arthur Weiss Nature Immunology7, 57–66
(January 2006); doi:10.1038/ni1291
| Abstract | Full Text (HTML/PDF) |
review article SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond
Gary A. Koretzky, Farhad Abtahian and Michael A. Silverman Nature Reviews Immunology6, 67–78
(January 2006); doi:10.1038/nri1750
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letter Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
Hans Häcker, Vanessa Redecke, Blagoy Blagoev, Irina Kratchmarova, Li-Chung Hsu, Gang G. Wang, Mark P. Kamps, Eyal Raz, Hermann Wagner, Georg Häcker, Matthias Mann and Michael Karin Nature439, 204–207
(12 January 2006); doi:10.1038/nature04369
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letter Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
Gagik Oganesyan, Supriya K. Saha, Beichu Guo, Jeannie Q. He, Arash Shahangian, Brian Zarnegar, Andrea Perry and Genhong Cheng Nature439, 208–211
(12 January 2006); doi:10.1038/nature04374
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article Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity
Jennifer E Fenner, Robyn Starr, Ann L Cornish, Jian-Guo Zhang, Donald Metcalf, Robert D Schreiber, Kathleen Sheehan, Douglas J Hilton, Warren S Alexander and Paul J Hertzog Nature Immunology7, 33–39
(January 2006); doi:10.1038/ni1287
| Abstract | Full Text (HTML/PDF) |
review article Dectin-1: a signalling non-TLR pattern-recognition receptor
Gordon D. Brown Nature Reviews Immunology6, 33–43
(January 2006); doi:10.1038/nri1745
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article IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis
Stefan Fichtner-Feigl, Warren Strober, Koji Kawakami, Raj K Puri and Atsushi Kitani Nature Medicine12, 99–106
(January 2006); doi:10.1038/nm1332
| Abstract | Full Text (HTML/PDF) |
review article Lymphocyte calcium signaling from membrane to nucleus
Elena M Gallo, Kirsten Canté-Barrett and Gerald R Crabtree Nature Immunology7, 25–32
(January 2006); doi:10.1038/ni1295
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article Mechanistic basis of pre-T cell receptor–mediated autonomous signaling critical for thymocyte development
Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Koji Ogata, Kumiko Sakata-Sogawa, Michio Hiroshima, David L Wiest, Makio Tokunaga and Takashi Saito Nature Immunology7, 67–75
(January 2006); doi:10.1038/ni1290
| Abstract | Full Text (HTML/PDF) |
review article Immune regulation by SLAM family receptors and SAP-related adaptors
André Veillette Nature Reviews Immunology6, 56–66
(January 2006); doi:10.1038/nri1761
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