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Research library: Immunology

2008: | July | June | May | April | March | February | January

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letter
IL-21 and TGF-β are required for differentiation of human TH17 cells
Li Yang et al.
Nature 454, 350–352
(17 July 2008); doi:10.1038/nature07021
| Summary | Full Text (HTML / PDF) |

article
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils
Bryan Heit et al.
Nature Immunology 9, 743–752
(July 2008); doi:10.1038/ni.1623
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news and views
PTEN gives neutrophils direction
Daniel D Billadeau
Nature Immunology 9, 716–718
(July 2008); doi:10.1038/ni0708-716
| Full Text (HTML / PDF) |

review
How regulatory T cells work
Dario A. A. Vignali, Lauren W. Collison & Creg J. Workman
Nature Reviews Immunology 8, 523–532
(July 2008); doi:10.1038/nri2343
| Summary | Full Text (HTML / PDF) |

research
Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1
Yukihiko Aikawa et al.
Nature Biotechnology 26, 817–823
(July 2008); doi:10.1038/nbt1412
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article
An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells
Erin J Adams, Pavel Strop, Sunny Shin, Yueh-Hsiu Chien & K Christopher Garcia
Nature Immunology 9, 777–784
(July 2008); doi:10.1038/ni.1620
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review
Deubiquitylation and regulation of the immune response
Shao-Cong Sun
Nature Reviews Immunology 8, 501–511
(July 2008); doi:10.1038/nri2337
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article
A Toll-like receptor 2–integrin β3 complex senses bacterial lipopeptides via vitronectin
Gisa Gerold et al.
Nature Immunology 9, 761–768
(July 2008); doi:10.1038/ni.1618
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article
The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells
Stephen J Loughran et al.
Nature Immunology 9, 810–819
(July 2008); doi:10.1038/ni.1617
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news and views
Erg in stem cells: a function emerges
Ellen V Rothenberg
Nature Immunology 9, 714–716
(July 2008); doi:10.1038/ni0708-714
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review
Colony-stimulating factors in inflammation and autoimmunity
John A. Hamilton
Nature Reviews Immunology 8, 533–544
(July 2008); doi:10.1038/nri2356
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article
A critical function for TGF-β signaling in the development of natural CD4+CD25+Foxp3+ regulatory T cells
Yongzhong Liu et al.
Nature Immunology 9, 632–640
(June 2008); doi:10.1038/ni.1607
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article
The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt
Nicolas Manel, Derya Unutmaz & Dan R Littman
Nature Immunology 9, 641–649
(June 2008); doi:10.1038/ni.1610
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article
A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses
Elisabetta Volpe et al.
Nature Immunology 9, 650–657
(June 2008); doi:10.1038/ni.1613
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news and views
Differentiation of human TH-17 cells does require TGF-β!
Anne O'Garra, Brigitta Stockinger & Marc Veldhoen
Nature Immunology 9, 588–590
(June 2008); doi:10.1038/ni0608-588
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article
Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
Edy Y Kim et al.
Nature Medicine 14, 633–640
(June 2008); doi:10.1038/nm1770
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news and views
Lung NKT cell commotion takes your breath away
Sebastian Joyce & Luc Van Kaer
Nature Medicine 14, 609–610
(June 2008); doi:10.1038/nm0608-609
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article
Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity
Jeff Holst et al.
Nature Immunology 9, 658–666
(June 2008); doi:10.1038/ni.1611
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news and views
CD3 ITAMs count!
Bernard Malissen
Nature Immunology 9, 583–584
(June 2008); doi:10.1038/ni0608-583
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article
The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues
Claudia Waskow et al.
Nature Immunology 9, 676–683
(June 2008); doi:10.1038/ni.1615
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news and views
Homeostasis of dendritic cell pool in lymphoid organs
Cedric Auffray, Yalin Emre & Frederic Geissmann
Nature Immunology 9, 584–586
(June 2008); doi:10.1038/ni0608-584
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Blocking TGF-β-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology
Terrence Town et al.
Nature Medicine 14, 681–687
(June 2008); doi:10.1038/nm1781
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letter
Draper-dependent glial phagocytic activity is mediated by Src and Syk family kinase signalling
Jennifer S. Ziegenfuss et al.
Nature 453, 935–939
(12 June 2008); doi:10.1038/nature06901
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article
Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
Rupesh H Amin & Mark S Schlissel
Nature Immunology 9, 613–622
(June 2008); doi:10.1038/ni.1612
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article
SLP-65 regulates immunoglobulin light chain gene recombination through the PI(3)K–PKB–Foxo pathway
Sebastian Herzog et al.
Nature Immunology 9, 623–631
(June 2008); doi:10.1038/ni.1616
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news and views
Foxos around make B cells tolerable
Marta A W Rowh & Craig H Bassing
Nature Immunology 9, 586–588
(June 2008); doi:10.1038/ni0608-586
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article
Transcription factor Mef2c is required for B cell proliferation and survival after antigen receptor stimulation
Peter R Wilker et al.
Nature Immunology 9, 603–612
(June 2008); doi:10.1038/ni.1609
| Summary | Full Text (HTML / PDF) |

review
Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou & Lieping Chen
Nature Reviews Immunology 8, 467–477
(June 2008); doi:10.1038/nri2326
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article
SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ
Yumiko Oishi et al.
Nature Medicine 14, 656–666
(June 2008); doi:10.1038/nm1756
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news and views
Multiple layers of metabolism
Mukesh K Jain
Nature Medicine 14, 603–604
(June 2008); doi:10.1038/nm0608-603
| Summary | Full Text (HTML / PDF) |

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NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Jordi Rius et al.
Nature 453, 807–811
(5 June 2008); doi:10.1038/nature06905
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article
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
Tatsukata Kawagoe et al.
Nature Immunology 9, 684–691
(June 2008); doi:10.1038/ni.1606
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news and views
IRAK2 takes its place in TLR signaling
Etienne Meylan & Jürg Tschopp
Nature Immunology 9, 581–582
(June 2008); doi:10.1038/ni0608-581
| Full Text (HTML / PDF) |

review
Inhibitory B7-family molecules in the tumour microenvironment
Weiping Zou & Lieping Chen
Nature Reviews Immunology 8, 467–477
(June 2008); doi:10.1038/nri2326
| Summary | Full Text (HTML / PDF) |

article
A microbial symbiosis factor prevents intestinal inflammatory disease
Sarkis K. Mazmanian, June L. Round & Dennis L. Kasper
Nature 453, 620–625
(29 May 2008); doi:10.1038/nature07008
| Summary | Full Text (HTML / PDF) |

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CLEC5A is critical for dengue-virus-induced lethal disease
Szu-Ting Chen et al.
Nature 453, 672–676
(29 May 2008); doi:10.1038/nature07013
| Summary | Full Text (HTML / PDF) |

article
The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes
Michaël Mingueneau et al.
Nature Immunology 9, 522–532
(May 2008); doi:10.1038/ni.1608
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news and views
CD3ε: PeRuSing for positive selection
Jonathan S Maltzman & Gary A Koretzky
Nature Immunology 9, 457–459
(May 2008); doi:10.1038/ni0508-457
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review
Molecular pathogenesis of T-cell leukaemia and lymphoma
Iannis Aifantis, Elizabeth Raetz & Silvia Buonamici
Nature Reviews Immunology 8, 380–390
(May 2008); doi:10.1038/nri2304
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article
Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1
Huazhang An et al.
Nature Immunology 9, 542–550
(May 2008); doi:10.1038/ni.1604
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news and views
'Fine tuning' TLR signaling
Luke A J O'Neill
Nature Immunology 9, 459–461
(May 2008); doi:10.1038/ni0508-459
| Full Text (HTML / PDF) |

review
Immunobiology of the TAM receptors
Greg Lemke & Carla V. Rothline
Nature Reviews Immunology 8, 327–336
(May 2008); doi:10.1038/nri2303
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review
TH17 cells in development: an updated view of their molecular identity and genetic programming
Chen Dong
Nature Reviews Immunology 8, 337–348
(May 2008); doi:10.1038/nri2295
| Summary | Full Text (HTML / PDF) |

article
Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma
Nandini Krishnamoorthy et al.
Nature Medicine 14, 565–573
(May 2008); doi:10.1038/nm1766
| Summary | Full Text (HTML / PDF) |

news and views
Dust mites' dirty dealings with dendritic cells
Dean Sheppard
Nature Medicine 14, 487–488
(May 2008); doi:10.1038/nm0508-487
| Summary | Full Text (HTML / PDF) |

article
Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1
Hui-Yan Li et al.
Nature Immunology 9, 533–541
(May 2008); doi:10.1038/ni.1600
| Summary | Full Text (HTML / PDF) |

review
Up on the tightrope: natural killer cell activation and inhibition
Lewis L Lanier
Nature Immunology 9, 495–502
(May 2008); doi:10.1038/ni1581
| Summary | Full Text (HTML / PDF) |

review
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Charles N. Serhan, Nan Chiang & Thomas E. Van Dyke
Nature Reviews Immunology 8, 349–361
(May 2008); doi:10.1038/nri2294
| Summary | Full Text (HTML / PDF) |

article
Functional roles for C5a receptors in sepsis
Daniel Rittirsch et al.
Nature Medicine 14, 551–557
(May 2008); doi:10.1038/nm1753
| Summary | Full Text (HTML / PDF) |

letter
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing ROR γt function
Liang Zhou et al.
Nature 453, 236–240
(8 May 2008); doi:10.1038/nature06878
| Summary | Full Text (HTML / PDF) |

article
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
Linda V Sinclair et al.
Nature Immunology 9, 513–521
(May 2008); doi:10.1038/ni.1603
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news and views
Moving out: mobilizing activated T cells from lymphoid tissues
Gabriel Berstein & Robert T Abraham
Nature Immunology 9, 455–457
(May 2008); doi:10.1038/ni0508-455
| Full Text (HTML / PDF) |

review
NLRs at the intersection of cell death and immunity
Jenny P.-Y. Ting, Stephen B. Willingham & Daniel T. Bergstralh
Nature Reviews Immunology 8, 372–379
(May 2008); doi:10.1038/nri2296
| Summary | Full Text (HTML / PDF) |

perspective
Not always the bad guys: B cells as regulators of autoimmune pathology
Simon Fillatreau, David Gray & Stephen M. Anderton
Nature Reviews Immunology 8, 391–397
(May 2008); doi:10.1038/nri2315
| Summary | Full Text (HTML / PDF) |

article
CD3-specific antibody-induced immune tolerance involves transforming growth factor-β from phagocytes digesting apoptotic T cells
Sylvain Perruche, Pin Zhang, Yongzhong Liu, Philippe Saas, Jeffrey A Bluestone & WanJun Chen
Nature Medicine 14, 528–535
(May 2008); doi:10.1038/nm1749
| Summary | Full Text (HTML / PDF) |

article
Rapid leukocyte migration by integrin-independent flowing and squeezing
Tim Lämmermann et al.
Nature 453, 51–55
(1 May 2008); doi:10.1038/nature06887
| Summary | Full Text (HTML / PDF) |

article
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor
Francisco J. Quintana et al.
Nature 453, 65–71
(1 May 2008); doi:10.1038/nature06880
| Summary | Full Text (HTML / PDF) |

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins
Marc Veldhoen et al.
Nature 453, 106–109
(1 May 2008); doi:10.1038/nature06881
| Summary | Full Text (HTML / PDF) |

news and views
Immunology: T cells hang in the balance
Emily A. Stevens & Christopher A. Bradfield
Nature 453, 46–47
(1 May 2008); doi:10.1038/453046a
| Full Text (HTML / PDF) |

article
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
Tiziana Di Pucchio et al.
Nature Immunology 9, 551–557
(May 2008); doi:10.1038/ni.1602
| Summary | Full Text (HTML / PDF) |

article
Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation
Sven Burgdorf, Christian Schölz, Andreas Kautz, Robert Tampé & Christian Kurts
Nature Immunology 9, 558–566
(May 2008); doi:10.1038/ni.1601
| Summary | Full Text (HTML / PDF) |

news and views
Cross-presentation: avoiding trafficking chaos?
Sudhir Pai Kasturi & Bali Pulendran
Nature Immunology 9, 461–463
(May 2008); doi:10.1038/ni0508-461
| Full Text (HTML / PDF) |

review
CCR7 and its ligands: balancing immunity and tolerance
Reinhold Förster, Ana Clara Davalos-Misslitz & Antal Rot
Nature Reviews Immunology 8, 362–371
(May 2008); doi:10.1038/nri2297
| Summary | Full Text (HTML / PDF) |

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Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility
Jacques Behmoaras et al.
Nature Genetics 40, 553–559
(May 2008); doi:10.1038/ng.137
| Summary | Full Text (HTML / PDF) |

review
The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting
Jeffrey A. Winkles
Nature Reviews Drug Discovery 7, 411–425
(May 2008); doi:10.1038/nrd2488
| Summary | Full Text (HTML / PDF) |

article
TRIM30α negatively regulates TLR-mediated NF-κB activation by targeting TAB2 and TAB3 for degradation
Mude Shi et al.
Nature Immunology 9, 369–377
(April 2008); doi:10.1038/ni1577
| Summary | Full Text (HTML / PDF) |

news and views
TRIM-ing down Tolls
Andrew G Bowie
Nature Immunology 9, 348–350
(April 2008); doi:10.1038/ni0408-348
| Full Text (HTML / PDF) |

article
Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain-containing proteins
Christine Cirl et al.
Nature Medicine 14, 399–406
(April 2008); doi:10.1038/nm1734
| Summary | Full Text (HTML / PDF) |

news and views
Bacteria fight back against Toll-like receptors
Luke A J O'Neill
Nature Medicine 14, 370–372
(April 2008); doi:10.1038/nm0408-370
| Summary | Full Text (HTML / PDF) |

article
TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes
Anna Yarilina et al.
Nature Immunology 9, 378–387
(April 2008); doi:10.1038/ni1576
| Summary | Full Text (HTML / PDF) |

article
Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
Hidenobu Kanda, Rebecca Newton, Russell Klein, Yuka Morita, Michael D Gunn & Steven D Rosen
Nature Immunology 9, 415–423
(April 2008); doi:10.1038/ni1573
| Summary | Full Text (HTML / PDF) |

news and views
A new player in lymphocyte homing
Dietmar Vestweber & Martin K Wild
Nature Immunology 9, 347–348
(April 2008); doi:10.1038/ni0408-347
| Full Text (HTML / PDF) |

review
Cis interactions of immunoreceptors with MHC and non-MHC ligands
Werner Held & Roy A. Mariuzza
Nature Reviews Immunology 8, 269–278
(April 2008); doi:10.1038/nri2278
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Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
Joshua D. Milner et al.
Nature 452, 773–776
(10 April 2008); doi:10.1038/nature06764
| Summary | Full Text (HTML / PDF) |

article
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira & Ruslan Medzhitov
Nature Immunology 9, 361–368
(April 2008); doi:10.1038/ni1569
| Summary | Full Text (HTML / PDF) |

news and views
Location, location, location: identifying the neighborhoods of LPS signaling
Colin Watts
Nature Immunology 9, 343–345
(April 2008); doi:10.1038/ni0408-343
| Full Text (HTML / PDF) |

article
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Mark E. Kleinman et al.
Nature 452, 591–597
(3 April 2008); doi:10.1038/nature06765
| Summary | Full Text (HTML / PDF) |

news and views
RNA interference: Generic block on angiogenesis
Raghu Kalluri & Keizo Kanasaki
Nature 452, 543–545
(3 April 2008); doi:10.1038/452543a
| Full Text (HTML / PDF) |

letter
Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation
Frank Niessen et al.
Nature 452, 654–658
(3 April 2008); doi:10.1038/nature06663
| Summary | Full Text (HTML / PDF) |

article
Regulation of T cell survival through coronin-1-mediated generation of inositol-1,4,5-trisphosphate and calcium mobilization after T cell receptor triggering
Philipp Mueller et al.
Nature Immunology 9, 424–431
(April 2008); doi:10.1038/ni1570
| Summary | Full Text (HTML / PDF) |

article
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance
Masatsugu Oh-hora et al.
Nature Immunology 9, 432–443
(April 2008); doi:10.1038/ni1574
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review
How dying cells alert the immune system to danger
Hajime Kono & Kenneth L. Rock
Nature Reviews Immunology 8, 279–289
(April 2008); doi:10.1038/nri2215
| Summary | Full Text (HTML / PDF) |

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Interferon-γ is a therapeutic target molecule for prevention of postoperative adhesion formation
Hisashi Kosaka, Tomohiro Yoshimoto, Takayuki Yoshimoto, Jiro Fujimoto & Kenji Nakanishi
Nature Medicine 14, 437–441
(April 2008); doi:10.1038/nm1733
| Summary | Full Text (HTML / PDF) |

article
The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1
K Venuprasad et al.
Nature Immunology 9, 245–253
(March 2008); doi:10.1038/ni1564
| Summary | Full Text (HTML / PDF) |

article
The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20
Noula Shembade et al.
Nature Immunology 9, 254–262
(March 2008); doi:10.1038/ni1563
| Summary | Full Text (HTML / PDF) |

news and views
Itching to end NF-κB
Vigo Heissmeyer & Anjana Rao
Nature Immunology 9, 227–229
(March 2008); doi:10.1038/ni0308-227
| Full Text (HTML / PDF) |

review
IgE in allergy and asthma today
Hannah J. Gould & Brian J. Sutton
Nature Reviews Immunology 8, 205–217
(March 2008); doi:10.1038/nri2273
| Summary | Full Text (HTML / PDF) |

review
Toll-like receptors — taking an evolutionary approach
François Leulier & Bruno Lemaitre
Nature Reviews Genetics 9, 165–178
(March 2008); doi:10.1038/nrg2303
| Summary | Full Text (HTML / PDF) |

article
Translational control of the innate immune response through IRF-7
Rodney Colina et al.
Nature 452, 323–328
(20 March 2008); doi:10.1038/nature06730
| Summary | Full Text (HTML / PDF) |

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Memory CD4 T cells emerge from effector T-cell progenitors
Laurie E. Harrington, Karen M. Janowski, James R. Oliver, Allan J. Zajac & Casey T. Weaver
Nature 452, 356–360
(20 March 2008); doi:10.1038/nature06672
| Summary | Full Text (HTML / PDF) |

article
HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells
James Arthos et al.
Nature Immunology 9, 301–309
(March 2008); doi:10.1038/ni1566
| Summary | Full Text (HTML / PDF) |

news and views
HIV's gut feeling
Quentin Sattentau
Nature Immunology 9, 225–227
(March 2008); doi:10.1038/ni0308-225
| Full Text (HTML / PDF) |

review
Interleukin 21: combination strategies for cancer therapy
Kresten Skak, Michael Kragh, Diana Hausman, Mark J. Smyth & Pallavur V. Sivakumar
Nature Reviews Drug Discovery 7, 231–240
(March 2008); doi:10.1038/nrd2482
| Summary | Full Text (HTML / PDF) |

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
You-Me Kim, Melanie M. Brinkmann, Marie-Eve Paquet & Hidde L. Ploegh
Nature 452, 234–238
(13 March 2008); doi:10.1038/nature06726
| Summary | Full Text (HTML / PDF) |

article
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-κB inhibitor A20
Beatrice Coornaert et al.
Nature Immunology 9, 263–271
(March 2008); doi:10.1038/ni1561
| Summary | Full Text (HTML / PDF) |

article
The proteolytic activity of the paracaspase MALT1 is key in T cell activation
Fabien Rebeaud et al.
Nature Immunology 9, 272–281
(March 2008); doi:10.1038/ni1568
| Summary | Full Text (HTML / PDF) |

news and views
Finally, MALT1 is a protease!
Linda M McAllister-Lucas & Peter C Lucas
Nature Immunology 9, 231–233
(March 2008); doi:10.1038/ni0308-231
| Full Text (HTML / PDF) |

perspective
The molecular basis for public T-cell responses?
Vanessa Venturi, David A. Price, Daniel C. Douek & Miles P. Davenport
Nature Reviews Immunology 8, 231–238
(March 2008); doi:10.1038/nri2260
| Summary | Full Text (HTML / PDF) |

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The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
Daniel A. Muruve et al.
Nature 452, 103–107
(6 March 2008); doi:10.1038/nature06664
| Summary | Full Text (HTML / PDF) |

article
Transcription factor KLF2 regulates the migration of naive T cells by restricting chemokine receptor expression patterns
Eric Sebzda, Zhiying Zou, John S Lee, Tao Wang & Mark L Kahn
Nature Immunology 9, 292–300
(March 2008); doi:10.1038/ni1565
| Summary | Full Text (HTML / PDF) |

news and views
Innocents abroad: regulating where naive T cells go
Barrett J Rollins
Nature Immunology 9, 233–235
(March 2008); doi:10.1038/ni0308-233
| Full Text (HTML / PDF) |

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Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
Jonathan B. Johnnidis et al.
Nature 451, 1125–1129
(28 February 2008); doi:10.1038/nature06607
| Summary | Full Text (HTML / PDF) |

article
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
Yukiko Tone, Keiji Furuuchi, Yoshitsugu Kojima, Mark L Tykocinski, Mark I Greene & Masahide Tone
Nature Immunology 9, 194–202
(February 2008); doi:10.1038/ni1549
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news and views
What turns on Foxp3?
Harald von Boehmer & Jens Nolting
Nature Immunology 9, 121–122
(February 2008); doi:10.1038/ni0208-121
| Full Text (HTML / PDF) |

article
Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells
Yi Ding, Shiqian Shen, Andreia C Lino, Maria A Curotto de Lafaille & Juan J Lafaille
Nature Medicine 14, 162–169
(February 2008); doi:10.1038/nm1707
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news and views
Safer, longer-lasting regulatory T cells with β-catenin
Jeffrey A Bluestone & Matthias Hebrok
Nature Medicine 14, 118–119
(February 2008); doi:10.1038/nm0208-118
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review
Complement evasion by human pathogens
John D. Lambris, Daniel Ricklin & Brian V. Geisbrecht
Nature Reviews Microbiology 6, 132–142
(February 2008); doi:10.1038/nrmicro1824
| Summary | Full Text (HTML / PDF) |

article
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
Hui-Chen Hsu et al.
Nature Immunology 9, 166–175
(February 2008); doi:10.1038/ni1552
| Summary | Full Text (HTML / PDF) |

news and views
IL-17 drives germinal center B cells?
David Tarlinton
Nature Immunology 9, 124–126
(February 2008); doi:10.1038/ni0208-124
| Full Text (HTML / PDF) |

review
Micromanagement of the immune system by microRNAs
Harvey F. Lodish, Beiyan Zhou, Gwen Liu & Chang-Zheng Chen
Nature Reviews Immunology 8, 120–130
(February 2008); doi:10.1038/nri2252
| Summary | Full Text (HTML / PDF) |

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Co-option of a default secretory pathway for plant immune responses
Chian Kwon et al.
Nature 451, 835–840
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Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5
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Nature Immunology 9, 203–215
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review
Of lineage and legacy: the development of mammalian hematopoietic stem cells
Elaine Dzierzak & Nancy A Speck
Nature Immunology 9, 129–136
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perpsective
The reverse stop-signal model for CTLA4 function
Christopher E. Rudd
Nature Reviews Immunology 8, 153–160
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review
Inter-kingdom signalling: communication between bacteria and their hosts
David T. Hughes & Vanessa Sperandio
Nature Reviews Microbiology 6, 111–120
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letter
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
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Nature 451, 725–729
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Acute upregulation of an NKG2D ligand promotes rapid reorganization of a local immune compartment with pleiotropic effects on carcinogenesis
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Nature Immunology 9, 146–154
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news and views
Stress gets under your skin
Daniel M Andrews & Mark J Smyth
Nature Immunology 9, 119–120
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Phagocytosis and comparative innate immunity: learning on the fly
Lynda M. Stuart & R. Alan Ezekowitz
Nature Reviews Immunology 8, 131–141
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brief communication
Switching constant domains enhances agonist activities of antibodies to a thrombopoietin receptor
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Nature Biotechnology 26, 209–211
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NLRX1 is a regulator of mitochondrial antiviral immunity
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Nature 451, 573–577
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'Tuning' of type I interferon-induced Jak–STAT1 signaling by calcium-dependent kinases in macrophages
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Nature Immunology 9, 186–193
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Activated leukocyte cell adhesion molecule promotes leukocyte trafficking into the central nervous system
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Nature Immunology 9, 137–145
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news and views
Lymphocyte transmigration in the brain: a new way of thinking
Boris P-L Lee & Beat A Imhof
Nature Immunology 9, 117–118
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Akirins are highly conserved nuclear proteins required for NF-κB-dependent gene expression in drosophila and mice
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Nature Immunology 9, 97–104
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news and views
Akirins versus infection
Bruce Beutler & Eva Marie Y Moresco
Nature Immunology 9, 7–9
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perspective
How microorganisms tip the balance between interleukin-12 family members
Stanislas Goriely, Markus F. Neurath & Michel Goldman
Nature Reviews Immunology 8, 81–86
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Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain
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Nature Immunology 9, 25–33
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The contribution of transcription factor IRF1 to the interferon-γ–interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells
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news and views
IRF1: a deus ex machina in TH1 differentiation
Derya Unutmaz & Jan Vilcek
Nature Immunology 9, 9–10
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review
Fcγ receptors as regulators of immune responses
Falk Nimmerjahn & Jeffrey V. Ravetch
Nature Reviews Immunology 8, 34–47
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The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics
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Nature Immunology 9, 42–53
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CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand
David Depoil et al.
Nature Immunology 9, 63–72
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Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13
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Nature Immunology 9, 73–80
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review
Launching the T-cell-lineage developmental programme
Ellen V. Rothenberg, Jonathan E. Moore & Mary A. Yui
Nature Reviews Immunology 8, 9–21
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Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
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Nature Medicine 14, 28–36
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news and views
Opening the gateway to tumors
Michael H Kershaw
Nature Medicine 14, 13–14
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From inflammation to sickness and depression: when the immune system subjugates the brain
Robert Dantzer, Jason C. O'Connor, Gregory G. Freund, Rodney W. Johnson & Keith W. Kelley
Nature Reviews Neuroscience 9, 46–56
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review
An integrated model of the recognition of Candida albicans by the innate immune system
Mihai G. Netea, Gordon D. Brown, Bart Jan Kullberg & Neil A. R. Gow
Nature Reviews Microbiology 6, 67–78
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Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses
Yoshihiro Baba, Keigo Nishida, Yoko Fujii, Toshio Hirano, Masaki Hikida & Tomohiro Kurosaki
Nature Immunology 9, 81–88
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Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels
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Nature Immunology 9, 89–96
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Immunological aspects of cancer chemotherapy
Laurence Zitvogel, Lionel Apetoh, François Ghiringhelli & Guido Kroemer
Nature Reviews Immunology 8, 59–73
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