Research library: Ion channels
2003: December | November
| October | September
| August | July
| June | May
| April | March
| February | January
Other Years: 2002 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009
December
review article
Merging functional studies with structures of inward-rectifier K+ channels
Delphine Bichet, Friederike A. Haass and Lily Yeh Jan
Nature Reviews Neuroscience 4, 957–967
(December 2003); doi:10.1038/nrn1244
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review article
The molecular basis of water transport in the brain
Mahmood Amiry-Moghaddam and Ole P. Ottersen
Nature Reviews Neuroscience 4, 991–1001
(December 2003); doi:10.1038/nrn1252
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letter
Genetically targeted chromophore-assisted light inactivation
Oded Tour, Rene M Meijer, David A Zacharias, Stephen R Adams & Roger Y Tsien
Nature Biotechnology 21, 1505–1508
(December 2003); doi:10.1038/nbt914
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letter
WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion
Kristopher T Kahle, Frederick H Wilson, Qiang Leng, Maria D Lalioti, Anthony D O'Connell, Ke Dong, Alicia K Rapson, Gordon G MacGregor, Gerhard Giebisch, Steven C Hebert and Richard P Lifton
Nature Genetics 35, 372–376
(December 2003); doi:10.1038/ng1271
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news and views
A molecular switch controlling renal sodium and potassium excretion
René J M Bindels
Nature Genetics 35, 302–303
(December 2003); doi:10.1038/ng1203-302
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article
Tom40 protein import channel binds to non-native proteins and prevents their aggregation
Masatoshi Esaki, Takashi Kanamori, Shuh-ichi Nishikawa, Injae Shin, Peter G Schultz and Toshiya Endo
Nature Structural Biology 10, 988–994
(December 2003); doi:10.1038/nsb1008
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news and views
Tom40: more than just a channel
Wolfgang Voos
Nature Structural Biology 10, 981–982
(December 2003); doi:10.1038/nsb1203-981
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review article
TRP channels as cellular sensors
David E. Clapham
Nature 426, 517–524
(04 December 2003); doi:10.1038/nature02196
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letter
A new sperm-specific Na+/H+ Exchanger required for sperm motility and fertility
Dan Wang, Shelby M. King, Timothy A. Quill, Lynda K. Doolittle and David L. Garbers
Nature Cell Biology 5, 1117–1122
(December 2003); doi:10.1038/ncb1072
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review article
The local differentiation of myelinated axons at nodes of Ranvier
Sebastian Poliak and Elior Peles
Nature Reviews Neuroscience 4, 968–980
(December 2003); doi:10.1038/nrn1253
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letters
Analyzing antibody specificity with whole proteome microarrays
Gregory A Michaud, Michael Salcius, Fang Zhou, Rhonda Bangham, Jaclyn Bonin, Hong Guo, Michael Snyder, Paul F Predki & Barry I Schweitzer
Nature Biotechnology 4, 1509–1512
(December 2003); doi:10.1038/nbt910
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November
letters to nature
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1
Sang Jeong Kim, Yu Shin Kim, Joseph P. Yuan, Ronald S. Petralia, Paul F. Worley and David J. Linden
Nature 426, 285–291
(20 November 2003); doi:10.1038/nature02162
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news and views
Muscles flex, axons die
Jean R. Wrathall
Nature Medicine 9, 1347–1348
(November 2003); doi:10.1038/nm1103-1347
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article
EXP-1 is an excitatory GABA-gated cation channel
Asim A Beg and Erik M Jorgensen
Nature Neuroscience 6, 1145–1152
(November 2003); doi:10.1038/nn1136
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news and views
Exciting guts with GABA
Jean-Marc Goaillard and Eve Marder
Nature Neuroscience 6, 1121–1122
(November 2003); doi:10.1038/nn1103-1121
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review article
The molecular logic of endocannabinoid signalling
Daniele Piomelli
Nature Reviews Neuroscience 4, 873–884
(November 2003); doi:10.1038/nrn1247
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October
letter
Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm
Xiao Fei Wang, Chen Xi Zhou, Qi Xian Shi, Yu Ying Yuan, Mei Kuen Yu, Louis Chukwuemeka Ajonuma, Lok Sze Ho, Pui Shan Lo, Lai Ling Tsang, Yu Liu, Sun Yi Lam, Ling Nga Chan, Wen Chao Zhao, Yiu Wa Chung and Hsiao Chang Chan
Nature Cell Biology 5, 902–906
(October 2003); doi:10.1038/ncb1047
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news and views
Of fertility, cystic fibrosis and the bicarbonate ion
Keith A. Sutton, Melissa K. Jungnickel and Harvey M. Florman
Nature Cell Biology 5, 857–859
(October 2003); doi:10.1038/ncb1003-857
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letters to nature
Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels
Xiang Dong Tang, Rong Xu, Mark F. Reynolds, Maria L. Garcia, Stefan H. Heinemann and Toshinori Hoshi
Nature 425, 531–535
(02 October 2003); doi:10.1038/nature02003
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September
article
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
Gavin Y. Oudit, Hui Sun, Maria G. Trivieri, Sheryl E. Koch, Fayez Dawood, Cameron Ackerley, Mehrdad Yazdanpanah, Greg J. Wilson, Arnold Schwartz, Peter P. Liu and Peter H. Backx
Nature Medicine 9, 1187–1194
(September 2003); doi:10.1038/nm920
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letters to nature
Structural basis for modulation and agonist specificity of HCN pacemaker channels
William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson and Eric Gouaux
Nature 425, 200–205
(11 September 2003); doi:10.1038/nature01922
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brief communication
Small-conductance, Ca2+-activated K+ channel SK3 generates age-related memory and LTP deficits
Thomas Blank, Ingrid Nijholt, Min-Jeong Kye, Jelena Radulovic and Joachim Spiess
Nature Neuroscience 6, 911–912
(September 2003); doi:10.1038/nn1101
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article
Plasticity of calcium channels in dendritic spines
Ryohei Yasuda, Bernardo L. Sabatini and Karel Svoboda
Nature Neuroscience 6, 948–955
(September 2003); doi:10.1038/nn1112
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August
news and views
Sealing the leak, healing the heart
Patrick Most and Walter J. Koch
Nature Medicine 9, 993–994
(August 2003); doi:10.1038/nm0803-993
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article
Modulation of glycine-activated ion channel function by G-protein βγ subunits
Gonzalo E. Yevenes, Robert W. Peoples, Juan C. Tapia, Jorge Parodi, Ximena Soto, Juan Olate and Luis G. Aguayo
Nature Neuroscience 6, 819–824
(August 2003); doi:10.1038/nn1095
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article
Localization of PIP2 activation gate in inward rectifier K+ channels
Jun Xiao, Xiao-guang Zhen and Jian Yang
Nature Neuroscience 6, 811–818
(August 2003); doi:10.1038/nn1090
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letters to nature
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
Makoto Tsuda, Yukari Shigemoto-Mogami, Schuichi Koizumi, Akito Mizokoshi, Shinichi Kohsaka, Michael W. Salter and Kazuhide Inoue
Nature 424, 778–783
(14 August 2003); doi:10.1038/nature01786
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news and views
Neurobiology: New player in pain
Edwin W. McCleskey
Nature 424, 729–730
(14 August 2003); doi:10.1038/424729a
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article
Structural basis for partial agonist action at ionotropic glutamate receptors
Rongsheng Jin, Tue G. Banke, Mark L. Mayer, Stephen F. Traynelis and Eric Gouaux
Nature Neuroscience 6, 803–810
(August 2003); doi:10.1038/nn1091
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news and views
Crystallizing our understanding of partial agonists
David S. Weiss and Yongchang Chang
Nature Neuroscience 6, 788–789
(August 2003); doi:10.1038/nn0803-788
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article
Endothelin-B receptor activation triggers an endogenous analgesic cascade at sites of peripheral injury
Alla Khodorova, Betsy Navarro, Laurence Sophie Jouaville, Jo-Ellen Murphy, Frank L Rice, Joseph E Mazurkiewicz, Denise Long-Woodward, Markus Stoffel, Gary R Strichartz, Rus Yukhananov and Gudarz Davar
Nature Medicine 9, 1055–1061
(August 2003); doi:10.1038/nm885
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review article
Attacking pain at its source: new perspectives on opioids
Christoph Stein, Michael Schäfer and Halina Machelska
Nature Medicine 9, 1003–1008
(August 2003); doi:10.1038/nm908
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article
Calcium regulates exocytosis at the level of single vesicles
Ute Becherer, Tobias Moser, Walter Stühmer and Martin Oheim
Nature Neuroscience 6, 846–853
(August 2003); doi:10.1038/nn1087
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July
letters to nature
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
Hiroyuki Watanabe, Joris Vriens, Jean Prenen, Guy Droogmans, Thomas Voets and Bernd Nilius
Nature 424, 434–438
(24 July 2003); doi:10.1038/nature01807
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news and views
Rules of conduct for the cystic fibrosis anion channel
Jeffrey J. Wine
Nature Medicine 9, 827–828
(July 2003); doi:10.1038/nm0703-827
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review article
ThermoTRP channels and beyond: mechanisms of temperature sensation
Ardem Patapoutian , Andrea M. Peier, Gina M. Story and Veena Viswanath
Nature Reviews Neuroscience 4, 529–539
(July 2003); doi:10.1038/nrn1141
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letters to nature
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
Stephen P. Kelley, James I. Dunlop, Ewen F. Kirkness, Jeremy J. Lambert and John A. Peters
Nature 424, 321–324
(17 July 2003); doi:10.1038/nature01788
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letters to nature
T-type calcium channel regulation by specific G-protein βγ subunits
Joshua T. Wolfe, Hongge Wang, Jason Howard, James C. Garrison and Paula Q. Barrett
Nature 424, 209–213
(10 July 2003); doi:10.1038/nature01772
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article
A T-type calcium channel required for normal function of a mammalian mechanoreceptor
Jung-Bum Shin, Carlos Martinez-Salgado, Paul A Heppenstall and Gary R Lewin
Nature Neuroscience 6, 724–730
(July 2003); doi:10.1038/nn1076
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review article
The motor infrastructure: from ion channels to neuronal networks
Sten Grillner
Nature Reviews Neuroscience 4, 573–586
(July 2003); doi:10.1038/nrn1137
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letters to nature
A TRPV family ion channel required for hearing in Drosophila
Janghwan Kim, Yun Doo Chung, Dae-young Park, SooKyung Choi, Dong Wook Shin, Heun Soh, Hye Won Lee, Wonseok Son, Jeongbin Yim, Chul-Seung Park, Maurice J. Kernan and Changsoo Kim
Nature 424, 81–84
(03 July 2003); doi:10.1038/nature01733
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news and views
Ion channels: Hearing aid
Rachel A. Dumont and Peter G. Gillespie
Nature 424, 28–29
(03 July 2003); doi:10.1038/424028a
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June
article
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
Markus Missler, Weiqi Zhang, Astrid Rohlmann, Gunnar Kattenstroth, Robert E. Hammer, Kurt Gottmann and Thomas C. Südhof
Nature 423, 939–948
(26 June 2003); doi:10.1038/nature01755
| Abstract | Full Text (HTML / PDF) |
news and views
Neurobiology: Synapses unplugged
J. Troy Littleton and Morgan Sheng
Nature 423, 931–932
(26 June 2003); doi:10.1038/423931a
| Full Text (HTML / PDF) |
article
Structure and gating mechanism of the acetylcholine receptor pore
Atsuo Miyazawa, Yoshinori Fujiyoshi and Nigel Unwin
Nature 423, 949–955
(26 June 2003); doi:10.1038/nature01748
| Abstract | Full Text (HTML / PDF) |
letters to nature
Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning
Makoto Nishiyama, Akemi Hoshino, Lily Tsai, John R. Henley, Yoshio Goshima, Marc Tessier-Lavigne, Mu-ming Poo and Kyonsoo Hong
Nature 423, 990–995
(26 June 2003); doi:10.1038/nature01751
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letters to nature
Control of dynamic CFTR selectivity by glutamate and ATP in epithelial cells
M. M. Reddy and P. M. Quinton
Nature 423, 756–760
(12 June 2003); doi:10.1038/nature01694
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article
Redox-sensitive extracellular gates formed by auxiliary b subunits of calcium-activated potassium channels
Xu-Hui Zeng, Xiao-Ming Xia and Christopher J Lingle
Nature Structural Biology 10, 448–454
(June 2003); doi:10.1038/nsb932
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article
AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists
Naoto Hoshi, Jia-Sheng Zhang, Miho Omaki, Takahiro Takeuchi, Shigeru Yokoyama, Nicolas Wanaverbecq, Lorene K Langeberg, Yukio Yoneda, John D Scott, David A Brown and Haruhiro Higashida
Nature Neuroscience 6, 564–571
(June 2003); doi:10.1038/nn1062
| Abstract | Full Text (HTML/PDF) |
May
article
X-ray structure of a voltage-dependent K+ channel
Youxing Jiang, Alice Lee, Jiayun Chen, Vanessa Ruta, Martine Caden, Brian T. Chait and Roderick Mackinnon
Nature 423, 33–41
(1 May 2003); doi:10.1038/nature01580
| Abstract | Full Text (HTML / PDF) |
article
The principle of gating charge movement in a voltage-dependent K+ channel
Youxing Jiang, Vanessa Ruta, Jiayun Chen, Alice Lee and Roderick Mackinnon
Nature 423, 42–48
(1 May 2003); doi:10.1038/nature01581
| Abstract | Full Text (HTML / PDF) |
news and views
Structural biology: Life's transistors
Fred J. Sigworth
Nature 423, 21–22
(1 May 2003); doi:10.1038/423021a
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April
article
A mouse model of episodic ataxia type-1
Paco S. Herson, Michael Virk, Nathan R. Rustay, Chris T. Bond, John C. Crabbe, John P. Adelman and James Maylie
Nature Neuroscience 6, 378–383
(April 2003); doi:10.1038/nn1025
| Abstract | Full Text (HTML/PDF) |
article
Zinc-mediated inhibition of GABAA receptors: discrete binding sites underlie subtype specificity
Alastair M. Hosie, Emma L. Dunne, Robert J. Harvey and Trevor G. Smart
Nature Neuroscience 6, 362–369
(April 2003); doi:10.1038/nn1030
| Abstract | Full Text (HTML/PDF) |
article
Hyperpolarization moves S4 sensors inward to open MVP, a methanococcal voltage-gated potassium channel
Federico Sesti, Sindhu Rajan, Rosana Gonzalez-Colaso, Natalia Nikolaeva and Steve A.N. Goldstein
Nature Neuroscience 6, 353–361
(April 2003); doi:10.1038/nn1028
| Abstract | Full Text (HTML/PDF) |
March
news and views
Arrhythmias of the heart: beyond ion channels
Andrew R. Marks
Nature Medicine 9, 263–264
(March 2003); doi:10.1038/nm0303-263
| Full Text (HTML/PDF) |
article
An evolutionarily conserved dileucine motif in Shal K+ channels mediates dendritic targeting
Jacqueline F. Rivera, Shoeb Ahmad, Michael W. Quick, Emily R. Liman and Don B. Arnold
Nature Neuroscience 6, 243–250
(March 2003); doi:10.1038/nn1020
| Abstract | Full Text (HTML/PDF) |
letters to nature
Glycine binding primes NMDA receptor internalization
Yi Nong, Yue-Qiao Huang, William Ju, Lorraine V. Kalia, Gholamreza Ahmadian, Yu Tian Wang and Michael W. Salter
Nature 422, 302–307
(20 March 2003); doi:10.1038/nature01497
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letters to nature
Functional analysis of an archaebacterial voltage-dependent K+ channel
Vanessa Ruta, Youxing Jiang, Alice Lee, Jiayun Chen and Roderick MacKinnon
Nature 422, 180–185
(13 March 2003); doi:10.1038/nature01473
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article
Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states
Dominique Derjean, Sandrine Bertrand, Gwendal Le Masson, Marc Landry, Valérie Morisset and Frédéric Nagy
Nature Neuroscience 6, 274–281
(March 2003); doi:10.1038/nn1016
| Abstract | Full Text (HTML/PDF) |
news and views
Plateau properties in pain pathways
Eve Marder
Nature Neuroscience 6, 210–212
(March 2003); doi:10.1038/nn0303-210
| Full Text (HTML/PDF) |
article
Elimination and strengthening of glycinergic/GABAergic connections during tonotopic map formation
Gunsoo Kim and Karl Kandler
Nature Neuroscience 6, 282–290
(March 2003); doi:10.1038/nn1015
| Abstract | Full Text (HTML/PDF) |
review article
Regulated portals of entry into the cell
Sean D. Conner and Sandra L. Schmid
Nature 422, 37–44
(06 March 2003); doi:10.1038/nature01451
| Summary | Full Text (HTML / PDF) |
February
article
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
Surya M. Nauli, Francis J. Alenghat, Ying Luo, Eric Williams, Peter Vassilev, Xiaogang Li, Andrew E. H. Elia, Weining Lu, Edward M. Brown, Stephen J. Quinn, Donald E. Ingber and Jing Zhou
Nature Genetics 33, 129–137
(February 2003); doi:10.1038/ng1076
| Abstract | Full Text (HTML/PDF) |
news and views
Ciliary signaling goes down the tubes
James P. Calvet
Nature Genetics 33, 113–114
(February 2003); doi:10.1038/ng1078
| Full Text (HTML/PDF) |
letters to nature
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
Peter J. Mohler, Jean-Jacques Schott, Anthony O. Gramolini, Keith W. Dilly, Silvia Guatimosim, William H. duBell, Long-Sheng Song, Karine Haurogné, Florence Kyndt, Mervat E. Ali, Terry B. Rogers, W. J. Lederer, Denis Escande, Herve Le Marec and Vann Bennett
Nature 421, 634–639
(06 February 2003); doi:10.1038/nature01335
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news and views
Human genetics: Lost anchors cost lives
Stanley Nattel
Nature 421, 587–590
(06 February 2003); doi:10.1038/421587a
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January
letters to nature
Coupling of agonist binding to channel gating in the GABAA
receptor
Thomas L. Kash, Andrew Jenkins, Jill C. Kelley, James R. Trudell and Neil
L. Harrison
Nature 421, 272–275
(16 January 2003); doi:10.1038/nature01280
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