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Research library: Ion channels

2009: | December | November | October | September | August | July | June | May | March | February | January

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article
X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
Alexander I. Sobolevsky, Michael P. Rosconi & Eric Gouaux
Nature 462, 745–756
(10 December 2009); doi:10.1038/nature08624
| Full Text (HTML / PDF) |

news and views
Neuroscience: Excitatory view of a receptor
Lonnie P. Wollmuth & Stephen F. Traynelis
Nature 462, 729–731
(10 December 2009); doi:10.1038/462729a
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article
Defective survival of naive CD8+ T lymphocytes in the absence of the β3 regulatory subunit of voltage-gated calcium channels
Mithilesh K Jha et al.
Nature Immunology 10, 1275–1282
(December 2009); doi:10.1038/ni.1793
| Summary | Full Text (HTML / PDF) |

article
Presynaptic α2δ-3 is required for synaptic morphogenesis independent of its Ca2+-channel functions
Peri T Kurshan, Asli Oztan & Thomas L Schwarz
Nature Neuroscience 12, 1415–1423
(November 2009); doi:10.1038/nn.2417
| Summary | Full Text (HTML / PDF) |

news and views
How to button a bouton with α2δs
Stephan J Sigrist & Andrew J R Plested
Nature Neuroscience 12, 1357–1358
(November 2009); doi:10.1038/nn1109-1357
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review
The origin and evolution of synapses
Tomás J. Ryan & Seth G. N. Grant
Nature Reviews Neuroscience 10, 701–712
(October 2009); doi:10.1038/nrn2717
| Summary | Full Text (HTML / PDF) |

article
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis
Torsten K Roepke et al.
Nature Medicine 15, 1186–1194
(October 2009); doi:10.1038/nm.2029
| Summary | Full Text (HTML / PDF) |

article
Nicotine activates the chemosensory cation channel TRPA1
Karel Talavera et al.
Nature Neuroscience 12, 1293–1299
(October 2009); doi:10.1038/nn.2379
| Summary | Full Text (HTML / PDF) |

article
Interactions between lipids and voltage sensor paddles detected with tarantula toxins
Mirela Milescu et al.
Nature Structural & Molecular Biology 16, 1080–1085
(October 2009); doi:10.1038/nsmb.1679
| Summary | Full Text (HTML / PDF) |

article
Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia
Hong-Shuo Sun et al.
Nature Neuroscience 12, 1300–1307
(October 2009); doi:10.1038/nn.2395
| Summary | Full Text (HTML / PDF) |

news and views
TR(I)Pping towards treatment for ischemia
David A Rempe, Takahiro Takano & Maiken Nedergaard
Nature Neuroscience 12, 1215–1216
(October 2009); doi:10.1038/nn1009-1215
| Full Text (HTML / PDF) |

article
Presynaptic CaV2 calcium channel traffic requires CALF-1 and the α2δ subunit UNC-36
Yasunori Saheki & Cornelia I Bargmann
Nature Neuroscience 12, 1257–1265
(October 2009); doi:10.1038/nn.2383
| Summary | Full Text (HTML / PDF) |

news and views
Calcium: an insignificant thing
Christian Frøkjær-Jensen & Erik M Jorgensen
Nature Neuroscience 12, 1213–1214
(October 2009); doi:10.1038/nn1009-1213
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article
Synthetic partial agonists reveal key steps in IP3 receptor activation
Ana M Rossi et al.
Nature Chemical Biology 5, 631–639
(September 2009); doi:10.1038/nchembio.195
| Summary | Full Text (HTML / PDF) |

review
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
Antoine Taly, Pierre-Jean Corringer, Denis Guedin, Pierre Lestage & Jean-Pierre Changeux
Nature Reviews Drug Discovery 8, 733–750
(September 2009); doi:10.1038/nrd2927
| Summary | Full Text (HTML / PDF) |

article
Kinetic basis of partial agonism at NMDA receptors
Cassandra L Kussius & Gabriela K Popescu
Nature Neuroscience 12, 1114–1120
(September 2009); doi:10.1038/nn.2361
| Summary | Full Text (HTML / PDF) |

article
A discrete alcohol pocket involved in GIRK channel activation
Prafulla Aryal, Hay Dvir, Senyon Choe & Paul A Slesinger
Nature Neuroscience 12, 988–995
(August 2009); doi:10.1038/nn.2358
| Summary | Full Text (HTML / PDF) |

article
Crystal structure of the ATP-gated P2X4 ion channel in the closed state
Toshimitsu Kawate, Jennifer Carlisle Michel, William T. Birdsong & Eric Gouaux
Nature 460, 592–598
(30 July 2009); doi:10.1038/nature08198
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article
Pore architecture and ion sites in acid-sensing ion channels and P2X receptors
Eric B. Gonzales, Toshimitsu Kawate & Eric Gouaux
Nature 460, 599–604
(30 July 2009); doi:10.1038/nature08218
| Full Text (HTML / PDF) |

news and views
Structural biology: Trimeric ion-channel design
Shai D. Silberberg & Kenton J. Swartz
Nature 460, 580–581
(July 2009); doi:10.1038/460580a
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article
Mapping the structure and conformational movements of proteins with transition metal ion FRET
Justin W Taraska, Michael C Puljung, Nelson B Olivier, Galen E Flynn & William N Zagotta
Nature Methods 6, 532–537
(July 2009); doi:10.1038/nmeth.1341
| Summary | Full Text (HTML / PDF) |

progress
New sites of action for GIRK and SK channels
Rafael Luján, James Maylie & John P. Adelman
Nature Reviews Neuroscience 10, 475–480
(July 2009); doi:10.1038/nrn2668
| Summary | Full Text (HTML / PDF) |

article
The N-terminal domain of GluR6-subtype glutamate receptor ion channels
Janesh Kumar, Peter Schuck, Rongsheng Jin & Mark L Mayer
Nature Structural & Molecular Biology 16, 631–638
(June 2009); doi:10.1038/nsmb.1613
| Summary | Full Text (HTML / PDF) |

article
Na+-activated K+ channels express a large delayed outward current in neurons during normal physiology
Gonzalo Budelli et al.
Nature Neuroscience 12, 745–750
(June 2009); doi:10.1038/nn.2313
| Summary | Full Text (HTML / PDF) |

letter
NAADP mobilizes calcium from acidic organelles through two-pore channels
Peter J. Calcraft et al.
Nature 459, 596–600
(28 May 2009); doi:10.1038/nature08030
| Full Text (HTML / PDF) |

article
BK channels modulate pre- and postsynaptic signaling at reciprocal synapses in retina
William N Grimes, Wei Li, Andrés E Chávez & Jeffrey S Diamond
Nature Neuroscience 12, 585–592
(May 2009); doi:10.1038/nn.2302
| Summary | Full Text (HTML / PDF) |

article
Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging
Maryline Beurg, Robert Fettiplace, Jong-Hoon Nam & Anthony J Ricci
Nature Neuroscience 12, 553–558
(May 2009); doi:10.1038/nn.2295
| Summary | Full Text (HTML / PDF) |

news and views
Bottoms up: transduction channels at tip link bases
Kateri J Spinelli & Peter G Gillespie
Nature Neuroscience 12, 529–530
(May 2009); doi:10.1038/nn0509-529
| Full Text (HTML / PDF) |

review
Ion channels versus ion pumps: the principal difference, in principle
David C. Gadsby
Nature Reviews Molecular Cell Biology 10, 344–352
(May 2009); doi:10.1038/nrm2668
| Summary | Full Text (HTML / PDF) |

article
Oxidation of a potassium channel causes progressive sensory function loss during aging
Shi-Qing Cai & Federico Sesti
Nature Neuroscience 12, 611–617
(May 2009); doi:10.1038/nn.2291
| Summary | Full Text (HTML / PDF) |

letter
Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle
Andrew M Bellinger et al.
Nature Medicine 15, 325–330
(March 2009); doi:10.1038/nm.1916
| Summary | Full Text (HTML / PDF) |

news and views
NO may prompt calcium leakage in dystrophic muscle
James G Tidball & S Armando Villalta
Nature Medicine 15, 243–244
(March 2009); doi:10.1038/nm0309-243
| Full Text (HTML / PDF) |

letter
SOAR and the polybasic STIM1 domains gate and regulate Orai channels
Joseph P. Yuan et al.
Nature Cell Biology 11, 337–343
(March 2009); doi:10.1038/ncb1842
| Summary | Full Text (HTML / PDF) |

review
Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?
Hildegard M. Schuller
Nature Reviews Cancer 9, 195–205
(March 2009); doi:10.1038/nrc2590
| Summary | Full Text (HTML / PDF) |

article
Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, γ-5
David Soto et al.
Nature Neuroscience 12, 277–285
(March 2009); doi:10.1038/nn.2266
| Summary | Full Text (HTML / PDF) |

article
De novo expression of Trpm4 initiates secondary hemorrhage in spinal cord injury
Volodymyr Gerzanich et al.
Nature Medicine 15, 185–191
(February 2009); doi:10.1038/nm.1899
| Summary | Full Text (HTML / PDF) |

review
Chloride channels as drug targets
Alan S. Verkman & Luis J. V. Galietta
Nature Reviews Drug Discovery 8, 153–171
(February 2009); doi:10.1038/nrd2780
| Summary | Full Text (HTML / PDF) |

letter
Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80
Boxun Lu et al.
Nature 457, 741–744
(05 February 2009); doi:10.1038/nature07579
| Summary | Full Text (HTML / PDF) |

review
Neurosensory mechanotransduction
Martin Chalfie
Nature Reviews Molecular Cell Biology 10, 44–52
(January 2009); doi:10.1038/nrm2595
| Summary | Full Text (HTML / PDF) |

review
Transient receptor potential channels: targeting pain at the source
Ardem Patapoutian, Simon Tate & Clifford J. Woolf
Nature Reviews Drug Discovery 8, 55–68
(January 2009); doi:10.1038/nrd2757
| Summary | Full Text (HTML / PDF) |

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