Research library: Kinases
2010:
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| March
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Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009
August
article
Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b
Chaofeng Han et al.
Nature Immunology 11, 734–742
(August 2010); doi:10.1038/ni.1908
| Summary | Full Text (HTML / PDF) |
news and views
Integrins limit the Toll
Terry K Means & Andrew D Luster
Nature Immunology 11, 691–693
(August 2010); doi:10.1038/ni0810-691
| Full Text (HTML / PDF) |
July
letter
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma
Nallasivam Palanisamy et al.
Nature Medicine 16, 781–787
(July 2010); doi:10.1038/nm.2166
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news and views
RAF translocations expand cancer targets
Martin McMahon
Nature Medicine 16, 749–750
(July 2010); doi:10.1038/nm0710-749
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article
Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles
Emma L Clayton et al.
Nature Neuroscience 13,
(July 2010); doi:10.1038/nn.2571
| Summary | Full Text (HTML / PDF) |
June
review
Signalling ballet in space and time
Boris N. Kholodenko, John F. Hancock & Walter Kolch
Nature Reviews Molecular Cell Biology 11, 414–426
(June 2010); doi:10.1038/nrm2901
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review
The SYK tyrosine kinase: a crucial player in diverse biological functions
Attila Mócsai, Jürgen Ruland & Victor L. J. Tybulewicz
Nature Reviews Immunology 10, 387–402
doi:10.1038/nri2765
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May
letter
Shugoshin–PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase
Tadashi Ishiguro, Koichi Tanaka, Takeshi Sakuno & Yoshinori Watanabe
Nature Cell Biology 12, 500–506
(May 2010); doi:10.1038/ncb2052
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article
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function
Nicholas Kwiatkowski et al.
Nature Chemical Biology 6, 359–368
(May 2010); doi:10.1038/nchembio.345
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brief communication
A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor
Kalinka Koteva et al.
Nature Chemical Biology 6, 327–329
(May 2010); doi:10.1038/nchembio.350
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news and views
Antibiotics: Vancomycin sensing
Michel Arthur
Nature Chemical Biology 6, 313–315
(May 2010); doi:10.1038/nchembio.356
| Full Text (HTML / PDF) |
April
letter
Phosphorylation of histone H3T6 by PKCβI controls demethylation at histone H3K4
Eric Metzger et al.
Nature 464, 792–796
(01 April 2010); doi:10.1038/nature08839
| Full Text (HTML / PDF) |
March
letter
Differential innate immune signalling via Ca2+ sensor protein kinases
Marie Boudsocq et al.
Nature 464, 418–422
(18 March 2010); doi:10.1038/nature08794
| Full Text (HTML / PDF) |
letter
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
Poulikos I. Poulikakos, Chao Zhang, Gideon Bollag, Kevan M. Shokat & Neal Rosen
Nature 464, 427–430
(18 March 2010); doi:10.1038/nature08902
| Full Text (HTML / PDF) |
letter
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
Georgia Hatzivassiliou et al.
Nature 464, 431–435
(18 March 2010); doi:10.1038/nature08833
| Full Text (HTML / PDF) |
review
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
Elena B. Pasquale
Nature Reviews Cancer 10, 165–180
(March 2010); doi:10.1038/nrc2806
| Summary | Full Text (HTML / PDF) |
February
review
PKC and the control of localized signal dynamics
Carine Rosse et al.
Nature Reviews Molecular Cell Biology 11, 103–112
(February 2010); doi:10.1038/nrm2847
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article
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
Nature Cell Biology 12, 119–131
(February 2010); doi:10.1038/ncb2012
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news and views
Mitochondria get a Parkin' ticket
Philipp Wild & Ivan Dikic
Nature Cell Biology 12, 104–106
(February 2010); doi:10.1038/ncb0210-104
| Full Text (HTML / PDF) |
January
letter
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
Charles J. David, Mo Chen, Marcela Assanah, Peter Canoll & James L. Manley
Nature 463, 364–368
(21 January 2010); doi:10.1038/nature08697
| Full Text (HTML / PDF) |
review
Multilayered control of gene expression by stress-activated protein kinases
Eulàlia de Nadal & Francesc Posas
The EMBO Journal 29, 4–13
(January 2010); doi:10.1038/emboj.2009.346
| Summary | Full Text (HTML / PDF) |
review
Kinase mutations in human disease: interpreting genotype–phenotype relationships
Piya Lahiry, Ali Torkamani, Nicholas J. Schork & Robert A. Hegele
Nature Reviews Genetics 11, 60–74
(January 2010); doi:10.1038/nrg2707
| Summary | Full Text (HTML / PDF) |
letter
Cdk2 suppresses cellular senescence induced by the c-myc oncogene
Stefano Campaner et al.
Nature Cell Biology 12, 54–59
(January 2010); doi:10.1038/ncb2004
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news and views
Myc and a Cdk2 senescence switch
Jan van Riggelen & Dean W. Felsher
Nature Cell Biology 12, 7–9
(January 2010); doi:10.1038/ncb0110-7
| Full Text (HTML / PDF) |
review
The nuts and bolts of AGC protein kinases
Laura R. Pearce, David Komander & Dario R. Alessi
Nature Reviews Molecular Cell Biology 11, 9–22
(January 2010); doi:10.1038/nrm2822
| Summary | Full Text (HTML / PDF) |
scientific reports
Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis
Giorgia Bracaglia et al.
EMBO reports 10, 1327–1333
(December 2009); doi:10.1038/embor.2009.217
| Summary | Full Text (HTML / PDF) |
letter
The Dbf4—Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4
Yi-Jun Sheu & Bruce Stillman
Nature 463, 113–117
(07 January 2010); doi:10.1038/nature08647
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letter
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats
Bancinyane L. Sibanda, Dimitri Y. Chirgadze & Tom L. Blundell
Nature 463, 118–121
(07 January 2010); doi:10.1038/nature08648
| Full Text (HTML / PDF) |
letter
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
Wenjun Zhou et al.
Nature 462, 1070–1074
(24 December 2009); doi:10.1038/nature08622
| Full Text (HTML / PDF) |
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