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Research library: Membrane traffic

2007: December | November | October | September | August | July | June | May | April | March | February | January

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article
SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment
Colin J. Traer et al.
Nature Cell Biology 9, 1370–1380
(December 2007); doi:10.1038/ncb1656
| Summary | Full Text (HTML / PDF) |

article
Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts
Nagaraj Balasubramanian, David W. Scott, J. David Castle, James E. Casanova & Martin Alexander Schwartz
Nature Cell Biology 9, 1381–1391
(December 2007); doi:10.1038/ncb1657
| Summary | Full Text (HTML / PDF) |

review
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes
Tom A. Rapoport
Nature 450, 663–669
(29 November 2007); doi:10.1038/nature06384
| Summary | Full Text (HTML / PDF) |

article
Crystal structure of a catalytic intermediate of the maltose transporter
Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson & Jue Chen
Nature 450, 515–521
(22 November 2007); doi:10.1038/nature06264
| Summary | Full Text (HTML / PDF) |

letter
A SNARE–adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles
Sharon E. Miller, Brett M. Collins, Airlie J. McCoy, Margaret S. Robinson & David J. Owen
Nature 450, 570–574
(22 November 2007); doi:10.1038/nature06353
| Summary | Full Text (HTML / PDF) |

article
Legionella pneumophila proteins that regulate Rab1 membrane cycling
Alyssa Ingmundson, Anna Delprato, David G. Lambright & Craig R. Roy
Nature 450, 365–369
(15 November 2007); doi:10.1038/nature06336
| Summary | Full Text (HTML / PDF) |

news and views
Microbiology: Pathogen drop-kick
Suzanne Pfeffer
Nature 450, 361–362
(15 November 2007); doi:10.1038/450361a
| Full Text (HTML / PDF) |

article
Synaptotagmin activates membrane fusion through a Ca2+-dependent trans interaction with phospholipids
Alexander Stein, Anand Radhakrishnan, Dietmar Riedel, Dirk Fasshauer & Reinhard Jahn
Nature Structural & Molecular Biology 14, 904–911
(October 2007); doi:10.1038/nsmb1305
| Summary | Full Text (HTML / PDF) |

letter
Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling
Oliver Daumke, Richard Lundmark, Yvonne Vallis, Sascha Martens, P. Jonathan G. Butler & Harvey T. McMahon
Nature 449, 923–922
(18 October 2007); doi:10.1038/nature06173
| Summary | Full Text (HTML / PDF) |

article
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
Yoshinori Takahashi et al.
Nature Cell Biology 9, 1142–1151
(October 2007); doi:10.1038/ncb1634
| Summary | Full Text (HTML / PDF) |

news and views
Shaping membranes into autophagosomes
Muriel Mari & Fulvio Reggiori
Nature Cell Biology 9, 1125–1127
(October 2007); doi:10.1038/ncb1007-1125
| Summary | Full Text (HTML / PDF) |

article
T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-α subunit controlled by the Rac activator Dock2
Yoshihiko Tanaka et al.
Nature Immunology 8, 1067–1075
(October 2007); doi:10.1038/ni1506
| Summary | Full Text (HTML / PDF) |

review
The many faces of actin: matching assembly factors with cellular structures
Ekta Seth Chhabra & Henry N. Higgs
Nature Cell Biology 9, 1110–1121
(October 2007); doi:10.1038/ncb1007-1110
| Summary | Full Text (HTML / PDF) |

perspective
New insights into BDNF function in depression and anxiety
Keri Martinowich, Husseini Manji & Bai Lu
Nature Neuroscience 10, 1089–1093
(September 2007); doi:10.1038/nn1971
| Summary | Full Text (HTML / PDF) |

letter
Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy
Anne-Sophie Nicot, Anne Toussaint, Valérie Tosch, Christine Kretz, Carina Wallgren-Pettersson, Erik Iwarsson, Helen Kingston, Jean-Marie Garnier, Valérie Biancalana, Anders Oldfors, Jean-Louis Mandel & Jocelyn Laporte
Nature Genetics 39, 1134–1139
(September 2007); doi:10.1038/ng2086
| Summary | Full Text (HTML / PDF) |

letter
Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic
Zita Balklava, Saumya Pant, Hanna Fares & Barth D. Grant
Nature Cell Biology 9, 1066–1073
(2007); doi:10.1038/ncb1627
| Summary | Full Text (HTML / PDF) |

news and views
PARtners for endocytosis
Frédéric Wissler & Michel Labouesse
Nature Cell Biology 9, 1027–1029
(2007); doi:10.1038/ncb0907-1027
| Full Text (HTML / PDF) |

article
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide
Giovanni D'Angelo, Elena Polishchuk, Giuseppe Di Tullio, Michele Santoro, Antonella Di Campli, Anna Godi, Gun West, Jacek Bielawski, Chia-Chen Chuang, Aarnoud C. van der Spoel, Frances M. Platt, Yusuf A. Hannun, Roman Polishchuk, Peter Mattjus & Maria Antonietta De Matteis
Nature 449, 62–67
(6 September 2007); doi:10.1038/nature06097
| Summary | Full Text (HTML / PDF) |

news and views
Cell biology: Taxi service for lipids
Anthony H. Futerman
Nature 449, 35–37
(6 September 2007); doi:10.1038/449035a
| Full Text (HTML / PDF) |

article
A Drosophila kinesin required for synaptic bouton formation and synaptic vesicle transport
Eunju Pack-Chung, Peri T Kurshan, Dion K Dickman & Thomas L Schwarz
Nature Neuroscience 10, 980–989
(August 2007); doi:10.1038/nn1936
| Summary | Full Text (HTML / PDF) |

letter
Regulated ATP release from astrocytes through lysosome exocytosis
Zhijun Zhang, Gang Chen, Wei Zhou, Aihong Song, Tao Xu, Qingming Luo, Wei Wang, Xiao-song Gu & Shumin Duan
Nature Cell Biology 9, 945–953
(August 2007); doi:10.1038/ncb1620
| Summary | Full Text (HTML / PDF) |

letter
Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice
Fudi Wang, Prasad N Paradkar, Angel O Custodio, Diane McVey Ward, Mark D Fleming, Dean Campagna, Kristina A Roberts, Victor Boyartchuk, William F Dietrich, Jerry Kaplan & Nancy C Andrews
Nature Genetics 39, 1025–1032
(August 2007); doi:10.1038/ng2059
| Summary | Full Text (HTML / PDF) |

review
Lysosomes: fusion and function
J. Paul Luzio, Paul R. Pryor & Nicholas A. Bright
Nature Reviews Molecular Cell Biology 8, 622–632
(August 2007); doi:10.1038/nrm2217
| Summary | Full Text (HTML / PDF) |

review
Pathways of clathrin-independent endocytosis
Satyajit Mayor & Richard E. Pagano
Nature Reviews Molecular Cell Biology 8, 603–612
(August 2007); doi:10.1038/nrm2216
| Summary | Full Text (HTML / PDF) |

article
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
John D. Carpten, Andrew L. Faber, Candice Horn, Gregory P. Donoho, Stephen L. Briggs, Christiane M. Robbins, Galen Hostetter, Sophie Boguslawski, Tracy Y. Moses, Stephanie Savage, Mark Uhlik, Aimin Lin, Jian Du, Yue-Wei Qian, Douglas J. Zeckner, Greg Tucker-Kellogg, Jeffrey Touchman, Ketan Patel, Spyro Mousses, Michael Bittner, Richard Schevitz, Mei-Huei T. Lai, Kerry L. Blanchard & James E. Thomas
Nature 448, 439–444
(26 July 2007); doi:10.1038/nature05933
| Summary | Full Text (HTML / PDF) |

letter
Functional diversification of closely related ARF-GEFs in protein secretion and recycling
Sandra Richter, Niko Geldner, Jarmo Schrader, Hanno Wolters, York-Dieter Stierhof, Gabino Rios, Csaba Koncz, David G. Robinson & Gerd Jürgens
Nature 448, 488–492
(26 July 2007); doi:10.1038/nature05967
| Summary | Full Text (HTML / PDF) |

review
Intermediate filaments: from cell architecture to nanomechanics
Harald Herrmann, Harald Bär, Laurent Kreplak, Sergei V. Strelkov & Ueli Aebi
Nature Reviews Molecular Cell Biology 8, 562–573
(July 2007); doi:10.1038/nrm2197
| Summary | Full Text (HTML / PDF) |

brief communication
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia
Karl-Heinz Grzeschik, Dorothea Bornholdt, Frank Oeffner, Arne König, María del Carmen Boente, Herbert Enders, Barbara Fritz, Michael Hertl, Ute Grasshoff, Katja Höfling, Vinzenz Oji, Mauro Paradisi, Christian Schuchardt, Zsuzsanna Szalai, Gianluca Tadini, Heiko Traupe & Rudolf Happle
Nature Genetics 39, 833–835
(July 2007); doi:10.1038/ng2052
| Summary | Full Text (HTML / PDF) |

brief communication
Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia
Xiaoling Wang, V Reid Sutton, J Omar Peraza-Llanes, Zhiyin Yu, Rebecca Rosetta, Ying-Chuck Kou, Tanya N Eble, Ankita Patel, Christina Thaller, Ping Fang & Ignatia B Van den Veyver
Nature Genetics 39, 836–838
(July 2007); doi:10.1038/ng2057
| Summary | Full Text (HTML / PDF) |

news and views
Wnt signaling in focal dermal hypoplasia
Amy S Paller
Nature Genetics 39, 820–821
(July 2007); doi:10.1038/ng0707-820
| Summary | Full Text (HTML / PDF) |

article
UNC-46 is required for trafficking of the vesicular GABA transporter
Kim Schuske, Mark T Palfreyman, Shigeki Watanabe & Erik M Jorgensen
Nature Neuroscience 10, 846–853
(July 2007); doi:10.1038/nn1920
| Summary | Full Text (HTML / PDF) |

letter
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J
Clement Y. Chow, Yanling Zhang, James J. Dowling, Natsuko Jin, Maja Adamska, Kensuke Shiga, Kinga Szigeti, Michael E. Shy, Jun Li, Xuebao Zhang, James R. Lupski, Lois S. Weisman & Miriam H. Meisler
Nature 448, 68–72
(5 July 2007); doi:10.1038/nature05876
| Summary | Full Text (HTML / PDF) |

article
BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation
Akira Yoshii & Martha Constantine-Paton
Nature Neuroscience 10, 702–711
(June 2007); doi:10.1038/nn1903
| Summary | Full Text (HTML / PDF) |

review
Inheritance and biogenesis of organelles in the secretory pathway
Martin Lowe & Francis A. Barr
Nature Reviews Molecular Cell Biology 8, 429–439
(June 2007); doi:10.1038/nrm2179
| Summary | Full Text (HTML / PDF) |

article
Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages
Young Jun Kang, Sung Ouk Kim, Shigeki Shimada, Motoyuki Otsuka, Alim Seit-Nebi, Byoung S Kwon, Tania H Watts & Jiahuai Han
Nature Immunology 8, 601–609
(June 2007); doi:10.1038/ni1471
| Summary | Full Text (HTML / PDF) |

review
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
C. Geoffrey Lau & R. Suzanne Zukin
Nature Reviews Neuroscience 8, 413–426
(June 2007); doi:10.1038/nrn2153
| Summary | Full Text (HTML / PDF) |

letter
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee & Jan O Lötvall
Nature Cell Biology 9, 654–659
(June 2007); doi:10.1038/ncb1596
| Summary | Full Text (HTML / PDF) |

article
Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics
Nelly Khidekel, Scott B Ficarro, Peter M Clark, Marian C Bryan, Danielle L Swaney, Jessica E Rexach, Yi E Sun, Joshua J Coon, Eric C Peters & Linda C Hsieh-Wilson
Nature Chemical Biology 3, 339–348
(June 2007); doi:10.1038/nchembio881
| Summary | Full Text (HTML / PDF) |

news and views
A QUICk look at O-GlcNAc dynamics
Lance Wells
Nature Chemical Biology 3, 303–304
(June 2007); doi:10.1038/nchembio0607-303
| Summary | Full Text (HTML / PDF) |

review
N-glycan structure dictates extension of protein folding or onset of disposal
Maurizio Molinari
Nature Chemical Biology 3, 313–320
(June 2007); doi:10.1038/nchembio880
| Summary | Full Text (HTML / PDF) |

news and views
A sugar-coated switch for cellular growth and arrest
Naoyuki Taniguchi
Nature Chemical Biology 3, 307–309
(June 2007); doi:10.1038/nchembio0607-307
| Summary | Full Text (HTML / PDF) |

letter
Aggregation and vesiculation of membrane proteins by curvature-mediated interactions
Benedict J. Reynwar, Gregoria Illya, Vagelis A. Harmandaris, Martin M. Müller, Kurt Kremer & Markus Deserno
Nature 447, 461–464
(24 May 2007); doi:10.1038/nature05840
| Summary | Full Text (HTML / PDF) |

review
The emerging shape of the ESCRT machinery
Roger L. Williams & Sylvie Urbé
Nature Reviews Molecular Cell Biology 8, 355–368
(May 2007); doi:10.1038/nrm2162
| Summary | Full Text (HTML / PDF) |

article
Structural basis for Rab GTPase activation by VPS9 domain exchange factors
Anna Delprato & David G Lambright
Nature Structural & Molecular Biology 14, 406–412
(May 2007); doi:10.1038/nsmb1232
| Summary | Full Text (HTML / PDF) |

letter
Cyclic AMP-regulated exocytosis of Escherichia coli from infected bladder epithelial cells
Brian L Bishop, Mathew J Duncan, Jeongmin Song, Guojie Li, David Zaas & Soman N Abraham
Nature Medicine 13, 625–630
(May 2007); doi:10.1038/nm1572
| Summary | Full Text (HTML / PDF) |

news and views
Flushing bacteria out of the bladder
Danelle S Eto & Matthew A Mulvey
Nature Medicine 13, 531–532
(May 2007); doi:10.1038/nm0507-531
| Summary | Full Text (HTML / PDF) |

perspective
Highway to the inner nuclear membrane: rules for the road
C. Patrick Lusk, Günter Blobel & Megan C. King
Nature Reviews Molecular Cell Biology 8, 414–420
(May 2007); doi:10.1038/nrm2165
| Summary | Full Text (HTML / PDF) |

review
Siglecs and their roles in the immune system
Paul R. Crocker, James C. Paulson & Ajit Varki
Nature Reviews Immunology 7, 255–266
(April 2007); doi:10.1038/nri2056
| Summary | Full Text (HTML / PDF) |

article
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes
Carolina Jancic, Ariel Savina, Christina Wasmeier, Tanya Tolmachova, Jamel El-Benna, Pham My-Chan Dang, Steve Pascolo, Maire-Anne Gougerot-Pocidalo, Graça Raposo, Miguel C. Seabra & Sebastian Amigorena
Nature Cell Biology 9, 367–378
(April 2007); doi:10.1038/ncb1552
| Summary | Full Text (HTML / PDF) |

news and views
New ways to arrest phagosome maturation
David G. Russell
Nature Cell Biology 9, 357–359
(April 2007); doi:10.1038/ncb0407-357
| Summary | Full Text (HTML / PDF) |

news and views
Rapid cargo shuttling by caveolae 366
Christina Karlsson Rosenthal
Nature Cell Biology 9, 366–366
(April 2007); doi:10.1038/ncb0407-366
| Summary | Full Text (HTML / PDF) |

perspective
Helping Wingless take flight: how WNT proteins are secreted
George Hausmann, Carla Bänziger & Konrad Basler
Nature Reveiws Molecular Cell Biology 8, 331–336
(April 2007); doi:10.1038/nrm2141
| Summary | Full Text (HTML / PDF) |

letter
Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism
Douglas A. Hattendorf, Anna Andreeva, Akanksha Gangar, Patrick J. Brennwald & William I. Weis
Nature 446, 567–571
(29 March 2007); doi:10.1038/nature05635
| Summary | Full Text (HTML / PDF) |

article
Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung
Phil Oh, Per Borgström, Halina Witkiewicz, Yan Li, Bengt J Borgström, Adrian Chrastina, Koji Iwata, Kurt R Zinn, Richard Baldwin, Jacqueline E Testa & Jan E Schnitzer
Nature Biotechnology 25, 327–337
(March 2007); doi:10.1038/nbt1292
| Summary | Full Text (HTML / PDF) |

review
Neuronal calcium sensor proteins: generating diversity in neuronal Ca2+ signalling
Robert D. Burgoyne
Nature Reviews Neurobiology 8, 182–193
(March 2007); doi:10.1038/nrn2093
| Summary | Full Text (HTML / PDF) |

review
Virus trafficking — learning from single-virus tracking
Boerries Brandenburg and Xiaowei Zhuang
Nature Reviews Microbiology 5, 197–208
(March 2007); doi:10.1038/nrmicro1615
| Summary | Full Text (HTML / PDF) |

article
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
Mickaël M Ménager, Gaël Ménasché, Maryse Romao, Perrine Knapnougel, Chen-Hsuan Ho, Mériem Garfa, Graça Raposo, Jérôme Feldmann, Alain Fischer & Geneviève de Saint Basile
Nature Immunology 8, 257–267
(March 2007); doi:10.1038/ni1431
| Summary | Full Text (HTML / PDF) |

review
The multiple faces of caveolae
Robert G. Parton and Kai Simons
Nature Reviews Molecular Cell Biology 8, 185–194
(March 2007); doi:10.1038/nrm2122
| Summary | Full Text (HTML / PDF) |

letter
TRAPPI tethers COPII vesicles by binding the coat subunit Sec23
Huaqing Cai, Sidney Yu, Shekar Menon, Yiying Cai, Darina Lazarova, Chunmei Fu, Karin Reinisch, Jesse C. Hay and Susan Ferro-Novick
Nature 445, 941–944
(22 February 2007); doi:10.1038/nature05527
| First Paragraph | Full Text (HTML / PDF) |

letter
Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2
Giulietta Spudich, Margarita V. Chibalina, Josephine Sui-Yan Au, Susan D. Arden, Folma Buss & John Kendrick-Jones
Nature Cell Biology 9, 176–183
(February 2007); doi:10.1038/ncb1531
| First Paragraph | Full Text (HTML / PDF) |

article
Drosophila spichthyin inhibits BMP signaling and regulates synaptic growth and axonal microtubules
Xinnan Wang, W Robert Shaw, Hilda T H Tsang, Evan Reid & Cahir J O'Kane
Nature Neuroscience 10, 177–185
(February 2007); doi:10.1038/nn1841
| Summary | Full Text (HTML / PDF) |

review
Lipid raft microdomains and neurotransmitter signalling
John A. Allen, Robyn A. Halverson-Tamboli and Mark M. Rasenick
Nature Reviews Neuroscience 8, 128–140
(February 2007); doi:10.1038/nrn2059
| Summary | Full Text (HTML / PDF) |

review
The WASP-WAVE protein network: connecting the membrane to the cytoskeleton
Tadaomi Takenawa and Shiro Suetsugu
Nature Reviews Molecular Cell Biology 8, 37–48
(January 2007); doi:10.1038/nrm2069
| Summary | Full Text (HTML / PDF) |

letter
Dynein is required for receptor sorting and the morphogenesis of early endosomes
Owen J. Driskell, Aleksandr Mironov, Victoria J. Allan & Philip G. Woodman
Nature Cell Biology 9, 113–120
(January 2007); doi:10.1038/ncb1525
| First Paragraph | Full Text (HTML / PDF) |

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