article Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
Susan M Kaech, Joyce T Tan, E John Wherry, Bogumila T Konieczny, Charles D Surh and Rafi Ahmed Nature Immunology4, 1191–1198
(December 2003); doi:10.1038/ni1009
| Abstract | Full Text (HTML/PDF) |
article Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2Kb
Julie Dam, Rongjin Guan, Kannan Natarajan, Nazzareno Dimasi, Lukasz K Chlewicki, David M Kranz, Peter Schuck, David H Margulies and Roy A Mariuzza Nature Immunology4, 1213–1222
(December 2003); doi:10.1038/ni1006
| Abstract | Full Text (HTML/PDF) |
review article T-cell-antigen recognition and the immunological synapse
Johannes B. Huppa and Mark M. Davis Nature Reviews Immunology3, 973–983
(December 2003); doi:10.1038/nri1245
| Abstract | Full Text (HTML / PDF) |
review article Dendritic-cell control of pathogen-driven T-cell polarization
Martien L. Kapsenberg Nature Reviews Immunology3, 984–993
(December 2003); doi:10.1038/nri1246
| Abstract | Full Text (HTML / PDF) |
article Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
Mary Tang, Guang Wang, Ping Lu, Richard H Karas, Mark Aronovitz, Scott P Heximer, Kevin M Kaltenbronn, Kendall J Blumer, David P Siderovski, Yan Zhu and Michael E Mendelsohn Nature Medicine9, 1506–1512
(December 2003); doi:10.1038/nm958
| Abstract | Full Text (HTML/PDF) |
review article Met, metastasis, motility and more
Carmen Birchmeier , Walter Birchmeier , Ermanno Gherardi and George F. Vande Woude Nature Reviews Molecular Cell Biology4, 915–925
(December 2003); doi:10.1038/nrm1261
| Abstract | Full Text (HTML / PDF) |
perspectives Opinion: Lateral phosphorylation propagation: an aspect of feedback signalling?
Christian Tischer and Philippe I. H. Bastiaens Nature Reviews Molecular Cell Biology4, 971–975
(December 2003); doi:10.1038/nrm1258
| Abstract | Full Text (HTML / PDF) |
article Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
Kasper Hoebe, Edith M Janssen, Sung O Kim, Lena Alexopoulou, Richard A Flavell, Jiahuai Han and Bruce Beutler Nature Immunology4, 1223–1229
(December 2003); doi:10.1038/ni1010
| Abstract | Full Text (HTML/PDF) |
news and views Adjuvants and their signaling pathways: beyond TLRs
Egil Lien and Douglas T Golenbock Nature Immunology4, 1162–1164
(December 2003); doi:10.1038/ni1203-1162
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review article CD28-mediated co-stimulation: a quantitative support for TCR signalling
Oreste Acuto and Frédérique Michel Nature Reviews Immunology3, 939–951
(December 2003); doi:10.1038/nri1248
| Abstract | Full Text (HTML / PDF) |
article Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice
Taku Okazaki, Yoshimasa Tanaka, Ryosuke Nishio, Tamotsu Mitsuiye, Akira Mizoguchi, Jian Wang, Masayoshi Ishida, Hiroshi Hiai, Akira Matsumori, Nagahiro Minato and Tasuku Honjo Nature Medicine9, 1477–1483
(December 2003); doi:10.1038/nm955
| Abstract | Full Text (HTML/PDF) |
article Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity
Urs Eriksson, Romeo Ricci, Lukas Hunziker, Michael O Kurrer, Gavin Y Oudit, Tania H Watts, Ivo Sonderegger, Kurt Bachmaier, Manfred Kopf and Josef M Penninger Nature Medicine9, 1484–1490
(December 2003); doi:10.1038/nm960
| Abstract | Full Text (HTML/PDF) |
news and views Dilated cardiomyopathy: learning to live with yourself
W Robb MacLellan and Aldons J Lusis Nature Medicine9, 1455–1456
(December 2003); doi:10.1038/nm1203-1455
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article The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons
John C Lin, Wei-Hsien Ho, Austin Gurney and Arnon Rosenthal Nature Neuroscience6, 1270–1276
(December 2003); doi:10.1038/nn1148
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review article Syndecans: proteoglycan regulators of cell-surface microdomains?
John R. Couchman Nature Reviews Molecular Cell Biology4, 926–938
(December 2003); doi:10.1038/nrm1257
| Abstract | Full Text (HTML / PDF) |
article Deletion of β-catenin impairs T cell development
Youyuan Xu, Daliya Banerjee, Joerg Huelsken, Walter Birchmeier and Jyoti Misra Sen Nature Immunology4, 1177–1182
(December 2003); doi:10.1038/ni1008
| Abstract | Full Text (HTML/PDF) |
article Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
Kelly D Smith, Erica Andersen-Nissen, Fumitaka Hayashi, Katie Strobe, Molly A Bergman, Sara L Rassoulian Barrett, Brad T Cookson and Alan Aderem Nature Immunology4, 1247–1253
(December 2003); doi:10.1038/ni1011
| Abstract | Full Text (HTML/PDF) |
news and views TLR5 takes aim at bacterial propeller
Jean-Marc Reichhart Nature Immunology4, 1159–1160
(December 2003); doi:10.1038/ni1203-1159
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review article Human CD8+ T-cell differentiation in response to viruses
René A. W. van Lier, Ineke J. M. ten Berge and Laila E. Gamadia Nature Reviews Immunology3, 931–939
(December 2003); doi:10.1038/nri1254
| Abstract | Full Text (HTML / PDF) |
article Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster
JianFeng Chen, Azucena Salas and Timothy A Springer Nature Structural Biology10, 995–1001
(December 2003); doi:10.1038/nsb1011
| Abstract | Full Text (HTML/PDF) |
November
letters to nature Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
Wenhui Li, Michael J. Moore, Natalya Vasilieva, Jianhua Sui, Swee Kee Wong, Michael A. Berne, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, Thomas C. Greenough, Hyeryun Choe & Michael Farzan Nature426, 450–454
(27 November 2003); doi:10.1038/nature02145
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article Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
Alberto Sánchez-Fueyo, Jane Tian, Dominic Picarella, Christoph Domenig, Xin Xiao Zheng, Catherine A. Sabatos, Natasha Manlongat, Orissa Bender, Thomas Kamradt, Vijay K. Kuchroo, José-Carlos Gutiérrez-Ramos, Anthony J. Coyle and Terry B. Strom Nature Immunology4, 1093–1101
(November 2003); doi:10.1038/ni987
| Abstract | Full Text (HTML/PDF) |
article Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
Catherine A Sabatos, Sumone Chakravarti, Eugene Cha, Anna Schubart, Alberto Sánchez-Fueyo, Xin Xiao Zheng, Anthony J. Coyle, Terry B. Strom, Gordon J. Freeman and Vijay K. Kuchroo Nature Immunology4, 1102–1110
(November 2003); doi:10.1038/ni988
| Abstract | Full Text (HTML/PDF) |
news and views I-Tim-izing the pathways of counter-regulation
Marsha Wills-Karp, Yasmine Belkaid and Christopher L. Karp Nature Immunology4, 1050–1052
(November 2003); doi:10.1038/ni1103-1050
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article Lymphotoxin pathway directs thymic Aire expression
Robert K. Chin, James C. Lo, Oliver Kim, Sarah E. Blink, Peter A. Christiansen, Pärt Peterson, Yang Wang, Carl Ware and Yang-Xin Fu Nature Immunology4, 1121–1127
(November 2003); doi:10.1038/ni982
| Abstract | Full Text (HTML/PDF) |
review article Aromatase inhibitors for breast cancer: lessons from the laboratory
Stephen R.D. Johnston and Mitch Dowsett Nature Reviews Cancer3, 821–831
(November 2003); doi:10.1038/nrc1211
| Abstract | Full Text (HTML / PDF) |
article Activity-induced targeting of profilin and stabilization of dendritic spine morphology
Manuel Ackermann and Andrew Matus Nature Neuroscience6, 1194–1200
(November 2003); doi:10.1038/nn1135
| Abstract | Full Text (HTML/PDF) |
review article Targeting the Nogo Receptor to Treat Central Nervous System Injuries
Daniel H. S. Lee, Stephen M. Strittmatter and Dinah W. Y. Sah Nature Reviews Drug Discovery2, 872–879
(November 2003); doi:10.1038/nrd1228
| Abstract | Full Text (HTML / PDF) |
article Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Wei Feng, Yawei Shi, Ming Li and Mingjie Zhang Nature Structural Biology10, 972–978
(November 2003); doi:10.1038/nsb992
| Abstract | Full Text (HTML/PDF) |
review article Scaffolding of antigen receptors for immunogenic versus tolerogenic signaling
Jesse E Jun and Christopher C Goodnow Nature Immunology4, 1057–1064
(November 2003); doi:10.1038/ni1001
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review article The molecular logic of endocannabinoid signalling
Daniele Piomelli Nature Reviews Neuroscience4, 873–884
(November 2003); doi:10.1038/nrn1247
| Abstract | Full Text (HTML / PDF) |
letters to nature Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells
Christine R. Rose, Robert Blum, Bruno Pichler, Alexandra Lepier, Karl W. Kafitz and Arthur Konnerth Nature426, 74–78
(06 November 2003); doi:10.1038/nature01983
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news and views Neurobiology: Signals that make waves
Louis F. Reichardt Nature426, 25–26
(06 November 2003); doi:10.1038/426025a
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letter Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis
Moritoshi Sato, Yoshibumi Ueda, Tokio Takagi and Yoshio Umezawa Nature Cell Biology5, 1016–1022
(November 2003); doi:10.1038/ncb1054
| First Paragraph | Full Text (HTML/PDF) |
article TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway
Masahiro Yamamoto, Shintaro Sato, Hiroaki Hemmi, Satoshi Uematsu, Katsuaki Hoshino, Tsuneyasu Kaisho, Osamu Takeuchi, Kiyoshi Takeda and Shizuo Akira Nature Immunology4, 1144–1150
(November 2003); doi:10.1038/ni986
| Abstract | Full Text (HTML/PDF) |
article Hepatocyte growth factor and its receptor are required for malaria infection
Margarida Carrolo, Silvia Giordano, Laura Cabrita-Santos, Simona Corso, Ana M Vigário, Susana Silva, Patricia Leirião, Daniel Carapau, Rosario Armas-Portela, Paolo M Comoglio, Ana Rodriguez and Maria M Mota Nature Medicine9, 1363–1369
(November 2003); doi:10.1038/nm947
| Abstract | Full Text (HTML/PDF) |
article Disruption of ErbB receptor signaling in adult non-myelinating Schwann cells causes progressive sensory loss
Suzhen Chen, Carlos Rio, Ru-Rong Ji, Pieter Dikkes, Richard E Coggeshall, Clifford J Woolf and Gabriel Corfas Nature Neuroscience6, 1186–1193
(November 2003); doi:10.1038/nn1139
| Abstract | Full Text (HTML/PDF) |
October
letters to nature Positioning of follicular dendritic cells within the spleen controls prion neuroinvasion
Marco Prinz , Mathias Heikenwalder, Tobias Junt, Petra Schwarz, Markus Glatzel, Frank L. Heppner, Yang-Xin Fu, Martin Lipp and Adriano Aguzzi Nature425, 957–962
(30 October 2003); doi:10.1038/nature02072
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article LAT regulates γd T cell homeostasis and differentiation
Selene Nuñez-Cruz, Enrique Aguado, Sylvie Richelme, Bruno Chetaille, Anne-Marie Mura, Mireille Richelme, Laurent Pouyet, Evelyne Jouvin-Marche, Luc Xerri, Bernard Malissen and Marie Malissen Nature Immunology4, 999–1008
(October 2003); doi:10.1038/ni977
| Abstract | Full Text (HTML/PDF) |
review article Macrophage migration inhibitory factor: a regulator of innate immunity
Thierry Calandra and Thierry Roger Nature Reviews Immunology3, 791–800
(October 2003); doi:10.1038/nri1200
| Abstract | Full Text (HTML / PDF) |
review article The SAP and SLAM families in immune responses and X-linked lymphoproliferative disease
Pablo Engel, Michael J. Eck and Cox Terhorst Nature Reviews Immunology3, 813–821
(October 2003); doi:10.1038/nri1202
| Abstract | Full Text (HTML / PDF) |
article Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress
Marianne B Müller, Stephan Zimmermann, Inge Sillaber, Thomas P Hagemeyer, Jan M Deussing, Peter Timpl, Michael S D Kormann, Susanne K Droste, Ralf Kühn, Johannes M H M Reul, Florian Holsboer and Wolfgang Wurst Nature Neuroscience6, 1100–1107
(October 2003); doi:10.1038/nn1123
| Abstract | Full Text (HTML/PDF) |
news and views Dissecting the components of the central response to stress
Emeran A Mayer and Michael S Fanselow Nature Neuroscience6, 1011–1012
(October 2003); doi:10.1038/nn1003-1011
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article Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
Jian Wang, ShuHong Liu, YangPing Fu, Jerry H Wang and YouMing Lu Nature Neuroscience6, 1039–1047
(October 2003); doi:10.1038/nn1119
| Abstract | Full Text (HTML/PDF) |
article Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation
Dietmar Schmitz, Jack Mellor, Joerg Breustedt and Roger A Nicoll Nature Neuroscience6, 1058–1063
(October 2003); doi:10.1038/nn1116
| Abstract | Full Text (HTML/PDF) |
article The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
Christopher A Love, Karl Harlos, Nasim Mavaddat, Simon J Davis, David I Stuart, E Yvonne Jones and Robert M Esnouf Nature Structural Biology10, 843–848
(October 2003); doi:10.1038/nsb977
| Abstract | Full Text (HTML/PDF) |
letters to nature Identification of the haematopoietic stem cell niche and control of the niche size
Jiwang Zhang, Chao Niu, Ling Ye, Haiyang Huang, Xi He, Wei-Gang Tong, Jason Ross, Jeff Haug, Teri Johnson, Jian Q. Feng, Stephen Harris, Leanne M. Wiedemann, Yuji Mishina and Linheng Li Nature425, 836–841
(23 October 2003); doi:10.1038/nature02041
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letters to nature Osteoblastic cells regulate the haematopoietic stem cell niche
L. M. Calvi, G. B. Adams, K. W. Weibrecht, J. M. Weber, D. P. Olson, M. C. Knight, R. P. Martin, E. Schipani, P. Divieti, F. R. Bringhurst, L. A. Milner, H. M. Kronenberg and D. T. Scadden Nature425, 841–846
(23 October 2003); doi:10.1038/nature02040
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news and views Stem cells: Interactive niches
Ihor R. Lemischka and Kateri A. Moore Nature425, 778–779
(23 October 2003); doi:10.1038/425778a
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review article Glycosylation regulates Notch signalling
Nicola Haines and Kenneth D. Irvine Nature Reviews Molecular Cell Biology4, 786–797
(October 2003); doi:10.1038/nrm1228
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review article The role of Notch in tumorigenesis: oncogene or tumour suppressor?
Freddy Radtke and Kenneth Raj Nature Reviews Cancer3, 756–767
(October 2003); doi:10.1038/nrc1186
| Summary | Full Text (HTML / PDF) |
article Sustained exposure to bacterial antigen induces interferon-γ-dependent T cell receptor ζ down-regulation and impaired T cell function
Noemí Bronstein-Sitton, Leonor Cohen-Daniel, Ilan Vaknin, Analía V Ezernitchi, Benny Leshem, Amal Halabi, Yael Houri-Hadad, Eugenia Greenbaum, Zichria Zakay-Rones, Lior Shapira and Michal Baniyash Nature Immunology4, 957–964
(October 2003); doi:10.1038/ni975
| Abstract | Full Text (HTML/PDF) |
news and views Unplugging the T cell receptor
Guido Poli and Claudio Bordignon Nature Immunology4, 943–944
(October 2003); doi:10.1038/ni1003-943
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article β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure
Jeanne Mialet Perez, Deborah A Rathz, Natalia N Petrashevskaya, Harvey S Hahn, Lynne E Wagoner, Arnold Schwartz, Gerald W Dorn II and Stephen B Liggett Nature Medicine9, 1300–1305
(October 2003); doi:10.1038/nm930
| Abstract | Full Text (HTML/PDF) |
news and views β-receptor polymorphisms: heart failure's crystal ball
David A Kass Nature Medicine9, 1260–1262
(October 2003); doi:10.1038/nm1003-1260
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review article Plasma-cell homing
Eric J. Kunkel and Eugene C. Butcher Nature Reviews Immunology3, 822–829
(October 2003); doi:10.1038/nri1203
| Abstract | Full Text (HTML / PDF) |
article Identification of PDGFR as a receptor for AAV-5 transduction
Giovanni Di Pasquale, Beverly L. Davidson, Colleen S. Stein, Inês Martins, Dominic Scudiero, Anne Monks and John A. Chiorini Nature Medicine9, 1306–1312
(October 2003); doi:10.1038/nm929
| Abstract | Full Text (HTML/PDF) |
article EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion
Manuel Zimmer, Amparo Palmer, Jenny Köhler and Rüdiger Klein Nature Cell Biology5, 869–878
(October 2003); doi:10.1038/ncb1045
| Abstract | Full Text (HTML/PDF) |
article Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion
Daniel J. Marston, Sarah Dickinson and Catherine D. Nobes Nature Cell Biology5, 879–888
(October 2003); doi:10.1038/ncb1044
| Abstract | Full Text (HTML/PDF) |
news and views How attraction turns to repulsion
David G. Wilkinson Nature Cell Biology5, 851–853
(October 2003); doi:10.1038/ncb1003-851
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review article Ras GTPases: integrins' friends or foes?
Kayoko Kinbara, Lawrence E. Goldfinger, Malene Hansen, Fan-Li Chou and Mark H. Ginsberg Nature Reviews Molecular Cell Biology4, 767–778
(October 2003); doi:10.1038/nrm1229
| Abstract | Full Text (HTML / PDF) |
brief communication Regulation of acetylcholine receptor clustering by the tumor suppressor APC
Junmei Wang, Zheng Jing, Lili Zhang, Guangdou Zhou, Joe Braun, Yun Yao and Zuo-Zhong Wang Nature Neuroscience6, 1017–1018
(October 2003); doi:10.1038/nn1128
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September
article SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
David Wald, Jinzhong Qin, Zhendong Zhao, Youcun Qian, Mayumi Naramura, Liping Tian, Jennifer Towne, John E. Sims, George R. Stark and Xiaoxia Li Nature Immunology4, 920–927
(September 2003); doi:10.1038/ni968
| Abstract | Full Text (HTML/PDF) |
news and views SIGIRR puts the brakes on Toll-like receptors
Luke A. J. O'Neill Nature Immunology4, 823–824
(September 2003); doi:10.1038/ni0903-823
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review article Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
Marie T. Filbin Nature Reviews Neuroscience4, 703–713
(September 2003); doi:10.1038/nrn1195
| Abstract | Full Text (HTML / PDF) |
letter CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth
Takashi Nishimura, Yuko Fukata, Katsuhiro Kato, Tomoya Yamaguchi, Yoshiharu Matsuura, Hiroyuki Kamiguchi and Kozo Kaibuchi Nature Cell Biology5, 819–826
(September 2003); doi:10.1038/ncb1039
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article The nonimmunoglobulin portion of λ5 mediates cell-autonomous pre-B cell receptor signaling
Kazuo Ohnishi and Fritz Melchers Nature Immunology4, 849–856
(September 2003); doi:10.1038/ni959
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news and views How pre-B cells know when they have it right
Mark Schlissel Nature Immunology4, 817–819
(September 2003); doi:10.1038/ni0903-817
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review article Signalling pathways of the TNF superfamily: a double-edged sword
Bharat B. Aggarwal Nature Reviews Immunology3, 745–756
(September 2003); doi:10.1038/nri1184
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article Enhanced T cell responses due to diacylglycerol kinase ζ deficiency
Xiao-Ping Zhong, Ehmonie A. Hainey, Benjamin A. Olenchock, Martha S. Jordan, Jonathan S. Maltzman, Kim E. Nichols, Hao Shen and Gary A. Koretzky Nature Immunology4, 882–890
(September 2003); doi:10.1038/ni958
| Abstract | Full Text (HTML/PDF) |
article Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor
Benjamin E. Willcox, Leonard M. Thomas and Pamela J. Bjorkman Nature Immunology4, 913–919
(September 2003); doi:10.1038/ni961
| Abstract | Full Text (HTML/PDF) |
review article DC-SIGN: escape mechanism for pathogens
Yvette van Kooyk and Teunis B. H. Geijtenbeek Nature Reviews Immunology3, 697–709
(September 2003); doi:10.1038/nri1182
| Abstract | Full Text (HTML / PDF) |
review article The role of FLT3 in haematopoietic malignancies
Derek L. Stirewalt and Jerald P. Radich Nature Reviews Cancer3, 650–665
(September 2003); doi:10.1038/nrc1169
| Abstract | Full Text (HTML / PDF) |
August
article The influence of the thymic environment on the CD4-versus-CD8 T lineage decision
Matilde Canelles, Melissa L. Park, Owen M. Schwartz and B. J. Fowlkes Nature Immunology4, 756–764
(August 2003); doi:10.1038/ni953
| Abstract | Full Text (HTML/PDF) |
news and views Deadbeat neighbors influence thymocyte lineage commitment
Pamela J. Fink Nature Immunology4, 727–728
(August 2003); doi:10.1038/ni0803-727
| Full Text (HTML/PDF) |
article Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors
Koho Iizuka, Olga V. Naidenko, Beatrice F. M. Plougastel, Daved H. Fremont and Wayne M. Yokoyama Nature Immunology4, 801–807
(August 2003); doi:10.1038/ni954
| Abstract | Full Text (HTML/PDF) |
letters to nature Complex between nidogen and laminin fragments reveals a paradigmatic β-propeller interface
Junichi Takagi , Yuting Yang , Jin-huan Liu, Jia-huai Wang and Timothy A. Springer Nature424, 969–974
(21 August 2003); doi:10.1038/nature01873
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perspectives Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis
Stefan Grünert, Martin Jechlinger and Hartmut Beug Nature Reviews Molecular Cell Biology4, 657–665
(August 2003); doi:10.1038/nrm1175
| Abstract | Full Text (HTML / PDF) |
article Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
K. Hoebe, X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han and B. Beutler Nature424, 743–748
(14 August 2003); doi:10.1038/nature01889
| Abstract | Full Text (HTML / PDF) |
news and views Immunology: Another toll road
Wen-Chen Yeh and Nien-Jung Chen Nature424, 736–737
(14 August 2003); doi:10.1038/424736a
| Full Text (HTML / PDF) |
letters to nature P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
Makoto Tsuda, Yukari Shigemoto-Mogami, Schuichi Koizumi, Akito Mizokoshi, Shinichi Kohsaka, Michael W. Salter and Kazuhide Inoue Nature424, 778–783
(14 August 2003); doi:10.1038/nature01786
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news and views Neurobiology: New player in pain
Edwin W. McCleskey Nature424, 729–730
(14 August 2003); doi:10.1038/424729a
| Full Text (HTML / PDF) |
review article Co-stimulatory members of the TNFR family: keys to effective T-cell immunity?
Michael Croft Nature Reviews Immunology3, 609–620
(August 2003); doi:10.1038/nri1148
| Abstract | Full Text (HTML / PDF) |
research article Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo
Karsten Mahnke, Yingjie Qian, Jürgen Knop and Alexander H. Enk Nature Biotechnology21, 903–908
(August 2003); doi:10.1038/nbt842
| Abstract | Full Text (HTML/PDF) |
letters to nature Induction of dendritic spines by an extracellular domain of AMPA receptor subunit GluR2
Maria Passafaro, Terunaga Nakagawa, Carlo Sala and Morgan Sheng Nature424, 677–681
(07 August 2003); doi:10.1038/nature01781
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news and views Neurobiology: A thorny issue
Peter H. Seeburg and Pavel Osten Nature424, 627–628
(07 August 2003); doi:10.1038/424627a
| Full Text (HTML / PDF) |
letters to nature Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1
Trever G. Bivona, Ignacio Pérez de Castro, Ian M. Ahearn, Theresa M. Grana, Vi K. Chiu, Peter J. Lockyer, Peter J. Cullen, Angel Pellicer, Adrienne D. Cox and Mark R. Philips Nature424, 694–698
(07 August 2003); doi:10.1038/nature01806
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news and views Signal transduction: Life on Mars, cellularly speaking
Pier Paolo Di Fiore Nature424, 624–625
(07 August 2003); doi:10.1038/424624a
| Full Text (HTML / PDF) |
article Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
Alexander N R Weber, Servane Tauszig-Delamasure, Jules A Hoffmann, Eric Lelièvre, Hugues Gascan, Keith P Ray, Mary A Morse, Jean-Luc Imler and Nicholas J Gay Nature Immunology4, 794–800
(August 2003); doi:10.1038/ni955
| Abstract | Full Text (HTML/PDF) |
news and views Toll gets tied in a knot
David Underhill Nature Immunology4, 723–724
(August 2003); doi:10.1038/ni0803-723
| Full Text (HTML/PDF) |
review article Class II cytokine receptors and their ligands: Key antiviral and inflammatory modulators
Jean-Christophe Renauld Nature Reviews Immunology3, 667–676
(August 2003); doi:10.1038/nri1153
| Summary | Full Text (HTML / PDF) |
article New role of δ2-glutamate receptors in AMPA receptor trafficking and cerebellar function
Hirokazu Hirai, Thomas Launey, Sumiko Mikawa, Takashi Torashima, Dai Yanagihara, Tsuyoshi Kasaura, Akihiro Miyamoto and Michisuke Yuzaki Nature Neuroscience6, 869–876
(August 2003); doi:10.1038/nn1086
| Abstract | Full Text (HTML/PDF) |
research article Targeting of proteins to membranes through hedgehog auto-processing
Sylvie Vincent, Abraham Thomas, Bradley Brasher and John D Benson Nature Biotechnology21, 936–940
(August 2003); doi:10.1038/nbt844
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article Continuous T cell receptor signaling required for synapse maintenance and full effector potential
Johannes B. Huppa, Michael Gleimer, Cenk Sumen and Mark M. Davis Nature Immunology4, 749–755
(August 2003); doi:10.1038/ni951
| Abstract | Full Text (HTML/PDF) |
July
article Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
Guido Serini, Donatella Valdembri, Sara Zanivan, Giulia Morterra, Constanze Burkhardt, Francesca Caccavari, Luca Zammataro, Luca Primo, Luca Tamagnone, Malcolm Logan, Marc Tessier-Lavigne, Masahiko Taniguchi, Andreas W. Püschel and Federico Bussolino Nature424, 391–397
(24 July 2003); doi:10.1038/nature01784
| Abstract | Full Text (HTML / PDF) |
letters to nature Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
Xin Wang, Shu-Mei Huong, Marie L. Chiu, Nancy Raab-Traub and Eng-Shang Huang Nature424, 456–461
(24 July 2003); doi:10.1038/nature01818
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article CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells
Ningshu Liu, Noriko Ohnishi, Lin Ni, Shizuo Akira and Kevin B. Bacon Nature Immunology4, 687–693
(July 2003); doi:10.1038/ni941
| Abstract | Full Text (HTML/PDF) |
news and views T-bet: The Toll-bridge to class-switch recombination?
Ian R. Rifkin and Ann Marshak-Rothstein Nature Immunology4, 650–652
(July 2003); doi:10.1038/ni0703-650
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article Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
Monica Autiero, Johannes Waltenberger, Didier Communi, Andrea Kranz, Lieve Moons, Diether Lambrechts, Jens Kroll, Stephane Plaisance, Maria De Mol, Françoise Bono, Stefanie Kliche, Guido Fellbrich, Kurt Ballmer-Hofer, Domenico Maglione, Ulrike Mayr-Beyrle, Mieke Dewerchin, Saskia Dombrowski, Danica Stanimirovic, Paul Van Hummelen, Christoph Dehio, Daniel J. Hicklin, Graziella Persico, Jean-Marc Herbert, David Communi, Masabumi Shibuya, Désiré Collen, Edward M. Conway and Peter Carmeliet Nature Medicine9, 936–943
(July 2003); doi:10.1038/nm884
| Abstract | Full Text (HTML/PDF) |
article Postsynaptic requirement for Abl kinases in assembly of the neuromuscular junction
Alexander J. Finn, Guoping Feng and Ann Marie Pendergast Nature Neuroscience6, 717–723
(July 2003); doi:10.1038/nn1071
| Abstract | Full Text (HTML/PDF) |
news and views Agrin / MuSK signaling: willing and Abl
Steven J. Burden, Christian Fuhrer and Stevan R. Hubbard Nature Neuroscience6, 653–654
(July 2003); doi:10.1038/nn0703-653
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perspectives Timeline: The bicyclam AMD3100 story
Erik De Clercq Nature Reviews Drug Discovery2, 581–587
(July 2003); doi:10.1038/nrd1134
| Abstract | Full Text (HTML / PDF) |
letters to nature Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex
Luc Jasmin, Samuel D. Rabkin, Alberto Granato, Abdennacer Boudah and Peter T. Ohara Nature424, 316–320
(17 July 2003); doi:10.1038/nature01808
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review article Extracellular calcium sensing and signalling
Aldebaran M. Hofer and Edward M. Brown Nature Reviews Molecular Cell Biology4, 530–538
(July 2003); doi:10.1038/nrm1154
| Summary | Full Text (HTML / PDF) |
article Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
Benedict Seddon, Peter Tomlinson and Rose Zamoyska Nature Immunology4, 680–686
(July 2003); doi:10.1038/ni946
| Abstract | Full Text (HTML/PDF) |
perspectives CpG motifs: the active ingredient in bacterial extracts?
Arthur M Krieg Nature Medicine9, 831–835
(July 2003); doi:10.1038/nm0703-831
| Abstract | Full Text (HTML/PDF) |
article Neurexin mediates the assembly of presynaptic terminals
Camin Dean, Francisco G Scholl, Jenny Choih, Shannon DeMaria, James Berger, Ehud Isacoff and Peter Scheiffele Nature Neuroscience6, 708–716
(July 2003); doi:10.1038/nn1074
| Abstract | Full Text (HTML/PDF) |
article A structural basis for immunodominant human T cell receptor recognition
Guillaume B E Stewart-Jones, Andrew J McMichael, John I Bell, David I Stuart and E Yvonne Jones Nature Immunology4, 657–663
(July 2003); doi:10.1038/ni942
| Abstract | Full Text (HTML/PDF) |
news and views The problem of plain vanilla peptides
Mark M Davis Nature Immunology4, 649–650
(July 2003); doi:10.1038/ni0703-649
| Full Text (HTML/PDF) |
review article An epigenetic view of helper T cell differentiation
K Mark Ansel, Dong U Lee and Anjana Rao Nature Immunology4, 616–623
(July 2003); doi:10.1038/ni0703-616
| Abstract | Full Text (HTML/PDF) |
letters to nature Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
J. Rodrigo Mora, Maria Rosa Bono, N. Manjunath, Wolfgang Weninger, Lois L. Cavanagh, Mario Rosemblatt and Ulrich H. von Andrian Nature424, 88–93
(03 July 2003); doi:10.1038/nature01726
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article BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
Norihiko Watanabe, Maya Gavrieli, John R Sedy, Jianfei Yang, Francesca Fallarino, Susan K Loftin, Michelle A Hurchla, Natalie Zimmerman, Julia Sim, Xingxing Zang, Theresa L Murphy, John H Russell, James P Allison and Kenneth M Murphy Nature Immunology4, 670–679
(July 2003); doi:10.1038/ni944
| Abstract | Full Text (HTML/PDF) |
news and views More negative feedback?
Anthony J Coyle and Jose-Carlos Gutierrez-Ramos Nature Immunology4, 647–648
(July 2003); doi:10.1038/ni0703-647
| Full Text (HTML/PDF) |
review article Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
Christopher E. Rudd and Helga Schneider Nature Reviews Immunology3, 544–556
(July 2003); doi:10.1038/nri1131
| Summary | Full Text (HTML / PDF) |
article A molecular switch between alternative conformational states in the complex of Ran and importin β1
Reinat Nevo, Cordula Stroh, Ferry Kienberger, David Kaftan, Vlad Brumfeld, Michael Elbaum, Ziv Reich and Peter Hinterdorfer Nature Structural Biology10, 553–557
(July 2003); doi:10.1038/nsb940
| Abstract | Full Text (HTML/PDF) |
June
article Structure and gating mechanism of the acetylcholine receptor pore
Atsuo Miyazawa, Yoshinori Fujiyoshi and Nigel Unwin Nature423, 949–955
(26 June 2003); doi:10.1038/nature01748
| Abstract | Full Text (HTML / PDF) |
article Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function
Erwan Bézard, Sandrine Ferry, Ulrich Mach, Holger Stark, Ludovic Leriche, Thomas Boraud, Christian Gross and Pierre Sokoloff Nature Medicine9, 762–767
(June 2003); doi:10.1038/nm875
| Abstract | Full Text (HTML/PDF) |
article Prostaglandin E2-EP4 signaling initiates skin immune responses by promoting migration and maturation of Langerhans cells
Kenji Kabashima, Daiji Sakata, Miyako Nagamachi, Yoshiki Miyachi, Kayo Inaba and Shuh Narumiya Nature Medicine9, 744–749
(June 2003); doi:10.1038/nm872
| Abstract | Full Text (HTML/PDF) |
letters to nature Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
Toshimasa Yamauchi, Junji Kamon, Yusuke Ito, Atsushi Tsuchida, Takehiko Yokomizo, Shunbun Kita, Takuya Sugiyama, Makoto Miyagishi, Kazuo Hara, Masaki Tsunoda, Koji Murakami, Toshiaki Ohteki, Shoko Uchida, Sato Takekawa, Hironori Waki, Nelson H. Tsuno, Yoichi Shibata, Yasuo Terauchi, Philippe Froguel, Kazuyuki Tobe, Shigeo Koyasu, Kazunari Taira, Toshio Kitamura, Takao Shimizu, Ryozo Nagai and Takashi Kadowaki Nature423, 762–769
(12 June 2003); doi:10.1038/nature01705
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article NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex
Nathalie Sans, Kate Prybylowski, Ronald S. Petralia, Kai Chang, Ya-Xian Wang, Claudia Racca, Stefano Vicini and Robert J. Wenthold Nature Cell Biology5, 520–530
(June 2003); doi:10.1038/ncb990
| Abstract | Full Text (HTML/PDF) |
news and views The return of the exocyst
Casper C. Hoogenraad and Morgan Sheng Nature Cell Biology5, 493–495
(June 2003); doi:10.1038/ncb0603-493
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perspectives When ubiquitin meets ubiquitin receptors: a signalling connection
Pier Paolo Di Fiore , Simona Polo and Kay Hofmann Nature Reviews Molecular Cell Biology4, 491–497
(June 2003); doi:10.1038/nrm1124
| Summary | Full Text (HTML / PDF) |
review article The biology of VEGF and its receptors
Napoleone Ferrara, Hans-Peter Gerber and Jennifer LeCouter Nature Medicine9, 669–676
(June 2003); doi:10.1038/nm0603-669
| Abstract | Full Text (HTML/PDF) |
review article Chemokine receptors: signposts to brain development and disease
Phuong B. Tran and Richard J. Miller Nature Reviews Neuroscience4, 444–455
(June 2003); doi:10.1038/nrn1116
| Summary | Full Text (HTML / PDF) |
article Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc
Andrew B. Herr, Edward R. Ballister and Pamela J. Bjorkman Nature423, 614–620
(05 June 2003); doi:10.1038/nature01685
| Abstract | Full Text (HTML / PDF) |
news and views Cancer: Out of air is not out of action
Donald P. Bottaro and Lance A. Liotta Nature423, 593–595
(05 June 2003); doi:10.1038/423593a
| Full Text (HTML / PDF) |
review article TREMs in the immune system and beyond
Marco Colonna Nature Reviews Immunology3, 445–453
(June 2003); doi:10.1038/nri1106
| Summary | Full Text (HTML / PDF) |
review article Roles and rules of kainate receptors in synaptic transmission
Juan Lerma Nature Reviews Neuroscience4, 481–495
(June 2003); doi:10.1038/nrn1118
| Summary | Full Text (HTML / PDF) |
May
letters to nature Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
G. Angus McQuibban, Saroj Saurya and Matthew Freeman Nature423, 537–541
(29 May 2003); doi:10.1038/nature01633
| First Paragraph | Full Text (HTML / PDF) |
letters to nature Modulation of oestrogen receptor signalling by association with the activated dioxin receptor
Fumiaki Ohtake, Ken-ichi Takeyama, Takahiro Matsumoto, Hirochika Kitagawa, Yasuji Yamamoto, Keiko Nohara, Chiharu Tohyama, Andree Krust, Junsei Mimura, Pierre Chambon, Junn Yanagisawa, Yoshiaki Fujii-Kuriyama and Shigeaki Kato Nature423, 545–550
(29 May 2003); doi:10.1038/nature01606
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news and views Gene expression: Oestrogen receptor hijacked
Jan J. Brosens and Malcolm G. Parker Nature423, 487–488
(29 May 2003); doi:10.1038/423487a
| Full Text (HTML / PDF) |
article Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells
Julio Aliberti, Jesus G. Valenzuela, Vern B. Carruthers, Sara Hieny, John Andersen, Hugues Charest, Caetano Reis e Sousa, Alan Fairlamb, Jose M. Ribeiro and Alan Sher Nature Immunology4, 485–490
(May 2003); doi:10.1038/ni915
| Abstract | Full Text (HTML/PDF) |
article Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
Renhai Cao, Ebba Bråkenhielm, Robert Pawliuk, David Wariaro, Mark J. Post, Eric Wahlberg, Philippe Leboulch and Yihai Cao Nature Medicine9, 604–613
(May 2003); doi:10.1038/nm848
| Abstract | Full Text (HTML/PDF) |
article Vomeronasal organ detects odorants in absence of signaling through main olfactory epithelium
Kien Trinh and Daniel R. Storm Nature Neuroscience6, 519–525
(May 2003); doi:10.1038/nn1039
| Abstract | Full Text (HTML/PDF) |
news and views Nosing into pheromone detectors
Ivan Rodriguez Nature Neuroscience6, 438–440
(May 2003); doi:10.1038/nn0503-438
| Full Text (HTML/PDF) |
article Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
Ho Min Kim, Kyung Sook Yu, Mi Eun Lee, Dong Ryeol Shin, Young Sang Kim, Sang-Gi Paik, Ook Joon Yoo, Hayyoung Lee and Jie-Oh Lee Nature Structural Biology10, 342–348
(May 2003); doi:10.1038/nsb925
| Abstract | Full Text (HTML/PDF) |
article Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport
Tomoo Shiba, Masato Kawasaki, Hiroyuki Takatsu, Terukazu Nogi, Naohiro Matsugaki, Noriyuki Igarashi, Mamoru Suzuki, Ryuichi Kato, Kazuhisa Nakayama and Soichi Wakatsuki Nature Structural Biology10, 386–393
(May 2003); doi:10.1038/nsb920
| Abstract | Full Text (HTML/PDF) |
article Modal gating of NMDA receptors and the shape of their synaptic response
Gabriela Popescu and Anthony Auerbach Nature Neuroscience6, 476–483
(May 2003); doi:10.1038/nn1044
| Abstract | Full Text (HTML/PDF) |
letters to nature Computational design of receptor and sensor proteins with novel functions
Loren L. Looger, Mary A. Dwyer, James J. Smith and Homme W. Hellinga Nature423, 185–190
(08 May 2003); doi:10.1038/nature01556
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news and views Computational biology: Biosensor design
William F. DeGrado Nature423, 132–133
(08 May 2003); doi:10.1038/423132a
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article Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
Gianni M. Di Guglielmo, Christine Le Roy, Anne F. Goodfellow and Jeffrey L. Wrana Nature Cell Biology5, 410–421
(May 2003); doi:10.1038/ncb975
| Abstract | Full Text (HTML/PDF) |
news and views Sliding doors: clathrin-coated pits or caveolae?
Michela Felberbaum-Corti, Françoise Gisou Van Der Goot and Jean Gruenberg Nature Cell Biology5, 382–384
(May 2003); doi:10.1038/ncb0503-382
| Full Text (HTML/PDF) |
article Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
Stephan R. Krutzik, Maria Teresa Ochoa, Peter A. Sieling, Satoshi Uematsu, Yolanda W. Ng, Annaliza Legaspi, Philip T. Liu, Stewart T. Cole, Paul J. Godowski, Yumi Maeda, Euzenir N. Sarno, Michael V. Norgard, Patrick J. Brennan, Shizuo Akira, Thomas H. Rea and Robert L. Modlin Nature Medicine9, 525–532
(May 2003); doi:10.1038/nm864
| Abstract | Full Text (HTML/PDF) |
review article Ligand–receptor binding revealed by the TNF family member TALL-1
Yingfang Liu, Xia Hong, John Kappler, Ling Jiang, Rongguang Zhang, Liangguo Xu, Cheol-Ho Pan Wesley E. Martin, Robert C. Murphy, Hong-Bing Shu, Shaodong Dai and Gongyi Zhang Nature423, 49–56
(1 May 2003); doi:10.1038/nature01543
| Summary | Full Text (HTML / PDF) |
letter EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation
Andrew R. Reynolds, Christian Tischer, Peter J. Verveer, Oliver Rocks and Philippe I. H. Bastiaens Nature Cell Biology5, 447–453
(May 2003); doi:10.1038/ncb981
| First Paragraph | Full Text (HTML/PDF) |
letter Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
Kaisa Haglund, Sara Sigismund, Simona Polo, Iwona Szymkiewicz, Pier Paolo Di Fiore and Ivan Dikic Nature Cell Biology5, 461–466
(May 2003); doi:10.1038/ncb983
| First Paragraph | Full Text (HTML/PDF) |
letter Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia
Pamela M. Pollock, Karine Cohen-Solal, Raman Sood, Jin Namkoong, Jeffrey J. Martino, Aruna Koganti, Hua Zhu, Christiane Robbins, Izabela Makalowska, Seung-Shick Shin, Yari Marin, Kathleen G. Roberts, Laura M. Yudt, Amy Chen, Jun Cheng, Arturo Incao, Heather W. Pinkett, Christopher L Graham, Karen Dunn, Steven M. Crespo-Carbone, Kerine R. Mackason, Kevin B. Ryan, Daniel Sinsimer, James Goydos, Kenneth R. Reuhl, Michael Eckhaus, Paul S. Meltzer, William J. Pavan, Jeffrey M. Trent and Suzie Chen Nature Genetics34, 108–112
(May 2003); doi:10.1038/ng1148
| First Paragraph | Full Text (HTML/PDF) |
article GABA uptake regulates cortical excitability via cell type-specific tonic inhibition
Alexey Semyanov, Matthew C. Walker and Dimitri M. Kullmann Nature Neuroscience6, 484–490
(May 2003); doi:10.1038/nn1043
| Abstract | Full Text (HTML/PDF) |
April
review article Immune functions encoded by the natural killer gene complex
Wayne M. Yokoyama and Beatrice F. M. Plougastel Nature Reviews Immunology3, 304–316
(April 2003); doi:10.1038/nri1055
| Summary | Full Text (HTML / PDF) |
article Wnt-mediated axon guidance via the Drosophila Derailed receptor
Shingo Yoshikawa, Randall D. McKinnon, Michelle Kokel and John B. Thomas Nature422, 583–588
(10 April 2003); doi:10.1038/nature01522
| Summary | Full Text (HTML / PDF) |
news and views Developmental biology: How neurons avoid derailment
Paul A. Garrity Nature422, 570–571
(10 April 2003); doi:10.1038/422570a
| Full Text (HTML / PDF) |
brief communication Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR-PLCβ4 signaling
Donghyun Park, Sukchan Lee, Kisun Jun, Yeon-Mi Hong, Do Young Kim, Yang In Kim and Hee-Sup Shin Nature Neuroscience6, 337–338
(April 2003); doi:10.1038/nn1033
| First Paragraph | Full Text (HTML/PDF) |
article Zinc-mediated inhibition of GABAA receptors: discrete binding sites underlie subtype specificity
Alastair M. Hosie, Emma L. Dunne, Robert J. Harvey and Trevor G. Smart Nature Neuroscience6, 362–369
(April 2003); doi:10.1038/nn1030
| Abstract | Full Text (HTML/PDF) |
review article Neurotrophins and their receptors: A convergence point for many signalling pathways
Moses V. Chao Nature Reviews Neuroscience4, 299–309
(April 2003); doi:10.1038/nrn1078
| Summary | Full Text (HTML / PDF) |
review article The role of receptor diffusion in the organization of the postsynaptic membrane
Daniel Choquet and Antoine Triller Nature Reviews Neuroscience4, 251–265
(April 2003); doi:10.1038/nrn1077
| Summary | Full Text (HTML / PDF) |
review Tumor necrosis factor signaling
H Wajant, K Pfizenmaier and P Scheurich Cell Death and Differentiation10, 45–65
(January 2003); doi:10.1038/sj.cdd.4401189
| Abstract |
review Apo2L/TRAIL and its death and decoy receptors
H N LeBlanc and A Ashkenazi Cell Death and Differentiation10, 66–75
(January 2003); doi:10.1038/sj.cdd.4401187
| Abstract |
March
review article Mannose 6-phosphate receptors: new twists in the tale
Pradipta Ghosh, Nancy M. Dahms and Stuart Kornfeld Nature Reviews Molecular Cell Biology4, 202–213
(March 2003); doi:10.1038/nrm1050
| Summary | Full Text (HTML / PDF) |
news and views Ready to partner
Mark X. Sliwkowski Nature Structural Biology10, 158–159
(March 2003); doi:10.1038/nsb0303-158
| Full Text (HTML/PDF) |
letters to nature Glycine binding primes NMDA receptor internalization
Yi Nong, Yue-Qiao Huang, William Ju, Lorraine V. Kalia, Gholamreza Ahmadian, Yu Tian Wang and Michael W. Salter Nature422, 302–307
(20 March 2003); doi:10.1038/nature01497
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letters to nature Segregation of receptor and ligand regulates activation of epithelial growth factor receptor
Paola D. Vermeer, Lisa A. Einwalter, Thomas O. Moninger, Tatiana Rokhlina, Jeffrey A. Kern, Joseph Zabner and Michael J. Welsh Nature422, 322–326
(20 March 2003); doi:10.1038/nature01440
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news and views Cell biology: Just mix and patch
Keith Mostov and Mirjam Zegers Nature422, 267–268
(20 March 2003); doi:10.1038/422267a
| Full Text (HTML / PDF) |
review article The nature of molecular recognition by T cells
Simon J. Davis, Shinji Ikemizu, Edward J. Evans, Lars Fugger, Talitha R. Bakker and P. Anton van der Merwe Nature Immunology4, 217–224
(March 2003); doi:10.1038/ni0303-217
| Abstract | Full Text (HTML/PDF) |
article Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
Shirley Shidu Yan, Zhi-Ying Wu, Hui Ping Zhang, Glaucia Furtado, Xi Chen, Shi Fang Yan, Ann Marie Schmidt, Chris Brown, Alan Stern, Juan Lafaille, Leonard Chess, David M. Stern and Hong Jiang Nature Medicine9, 287–293
(March 2003); doi:10.1038/nm831
| Abstract | Full Text (HTML/PDF) |
letter Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant
Daria E. Siekhaus and David G. Drubin Nature Cell Biology5, 231–235
(March 2003); doi:10.1038/ncb941
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brief communication The spindle-associated transmembrane protein Axs identifies a membranous structure ensheathing the meiotic spindle
Joseph Kramer and R. Scott Hawley Nature Cell Biology5, 261–263
(March 2003); doi:10.1038/ncb944
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article Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states
Dominique Derjean, Sandrine Bertrand, Gwendal Le Masson, Marc Landry, Valérie Morisset and Frédéric Nagy Nature Neuroscience6, 274–281
(March 2003); doi:10.1038/nn1016
| Abstract | Full Text (HTML/PDF) |
news and views Plateau properties in pain pathways
Eve Marder Nature Neuroscience6, 210–212
(March 2003); doi:10.1038/nn0303-210
| Full Text (HTML/PDF) |
article Elimination and strengthening of glycinergic/GABAergic connections during tonotopic map formation
Gunsoo Kim and Karl Kandler Nature Neuroscience6, 282–290
(March 2003); doi:10.1038/nn1015
| Abstract | Full Text (HTML/PDF) |
review article Signal dispersal and transduction through the endocytic pathway
Marcos González-Gaitán Nature Reviews Molecular Cell Biology4, 213–224
(March 2003); doi:10.1038/nrm1053
| Summary | Full Text (HTML / PDF) |
February
letter SAP couples Fyn to SLAM immune receptors
Betty Chan, Arpad Lanyi, Hyun Kyu Song, Jan Griesbach, Maria Simarro-Grande, Florence Poy, Duncan Howie, Janos Sumegi, Cox Terhorst and Michael J. Eck Nature Cell Biology5, 155–160
(February 2003); doi:10.1038/ncb920
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article CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling
Claudine Irles, Antony Symons, Frédérique Michel, Talitha R. Bakker, P. Anton van der Merwe and Oreste Acuto Nature Immunology4, 189–197
(February 2003); doi:10.1038/ni877
| Abstract | Full Text (HTML/PDF) |
review article CD3-specific antibody-induced active tolerance: from bench to bedside
Lucienne Chatenoud Nature Reviews Immunology3, 123–132
(February 2003); doi:10.1038/nri1000
| Summary | Full Text (HTML / PDF) |
perspectives Timeline: Innate immune sensing and its roots: the story of endotoxin
Bruce Beutler and Ernst Th. Rietschel Nature Reviews Immunology3, 169–176
(February 2003); doi:10.1038/nri1004
| Summary | Full Text (HTML / PDF) |
article Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells
Jeong-Hyeon Sohn, Puran S. Bora, Hye-Jung Suk, Hector Molina, Henry J. Kaplan and Nalini S. Bora Nature Medicine9, 206–212
(February 2003); doi:10.1038/nm814
| Abstract | Full Text (HTML/PDF) |
letters to nature STAT3 signalling is required for leptin regulation of energy balance but not reproduction
Sarah H. Bates, Walter H. Stearns, Trevor A. Dundon, Markus Schubert, Annette W. K. Tso, Yongping Wang, Alexander S. Banks, Hugh J. Lavery, Asma K. Haq, Eleftheria Maratos-Flier, Benjamin G. Neel, Michael W. Schwartz and Martin G. Myers Jr Nature421, 856–859
(20 February 2003); doi:10.1038/nature01388
| First Paragraph | Full Text (HTML / PDF) |
news and views Molecular chaperones: Plugging the transport gap
R. John Ellis Nature421, 801–802
(20 February 2003); doi:10.1038/421801a
| Full Text (HTML / PDF) |
letters to nature Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
Hyun-Soo Cho, Karen Mason, Kasra X. Ramyar, Ann Marie Stanley, Sandra B. Gabelli, Dan W. Denney Jr and Daniel J. Leahy Nature421, 756–760
(13 February 2003); doi:10.1038/nature01392
| First Paragraph | Full Text (HTML / PDF) |
review article NALPs: a novel protein family involved in inflammation
Jürg Tschopp, Fabio Martinon and Kimberly Burns Nature Reviews Molecular Cell Biology4, 95–104
(February 2003); doi:10.1038/nrm1019
| Summary | Full Text (HTML / PDF) |
article TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-β induction
Hiroyuki Oshiumi, Misako Matsumoto, Kenji Funami, Takashi Akazawa and Tsukasa Seya Nature Immunology4, 161–167
(February 2003); doi:10.1038/ni886
| Abstract | Full Text (HTML/PDF) |
news and views Toll signaling: the TIReless quest for specificity
Jean-Luc Imler and Jules A. Hoffmann Nature Immunology4, 105–106
(February 2003); doi:10.1038/ni0203-105
| Full Text (HTML/PDF) |
review article Adaptors as central mediators of signal transduction in immune cells
Martha S. Jordan, Andrew L. Singer and Gary A. Koretzky Nature Immunology4, 110–116
(February 2003); doi:10.1038/ni0203-110
| Abstract | Full Text (HTML/PDF) |
article Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
Keith K. Murai, Louis N. Nguyen, Fumitoshi Irie, Yu Yamaguchi and Elena B. Pasquale Nature Neuroscience6, 153–160
(February 2003); doi:10.1038/nn994
| Abstract | Full Text (HTML/PDF) |
news and views Ephrins keep dendritic spines in shape
Scott M. Thompson Nature Neuroscience6, 103–104
(February 2003); doi:10.1038/nn0203-103
| Full Text (HTML/PDF) |
letter Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation
Sylvain Latour, Romain Roncagalli, Riyan Chen, Marcin Bakinowski, Xiaochu Shi, Pamela L. Schwartzberg, Dominique Davidson and André Veillette Nature Cell Biology5, 149–154
(February 2003); doi:10.1038/ncb919
| First Paragraph | Full Text (HTML/PDF) |
article LAB: A new membrane-associated adaptor molecule in B cell activation
Erin Janssen, Minghua Zhu, Weijia Zhang, Surapong Koonpaew and Weiguo Zhang Nature Immunology4, 117–123
(February 2003); doi:10.1038/ni882
| Abstract | Full Text (HTML/PDF) |
review article Interleukin-12 and the regulation of innate resistance and adaptive immunity
Giorgio Trinchieri Nature Reviews Immunology3, 133–146
(February 2003); doi:10.1038/nri1001
| Summary | Full Text (HTML / PDF) |
article PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity
José A. Esteban, Song-Hai Shi, Christopher Wilson, Mutsuo Nuriya, Richard L. Huganir and Roberto Malinow Nature Neuroscience6, 136–143
(February 2003); doi:10.1038/nn997
| Abstract | Full Text (HTML/PDF) |
article Activation of NR1/NR2B NMDA receptors
Tue G. Banke and Stephen F. Traynelis Nature Neuroscience6, 144–152
(February 2003); doi:10.1038/nn1000
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January
article Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions
Kiki Tesselaar, Ramon Arens, Gijs M.W. van Schijndel, Paul A. Baars, Martin A. van der Valk, Jannie Borst, Marinus H.J. van Oers and René A.W. van Lier Nature Immunology4, 49–54
(January 2003); doi:10.1038/ni869
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article TCRs with high affinity for foreign pMHC show self-reactivity
Phillip D. Holler, Lukasz K. Chlewicki and David M. Kranz Nature Immunology4, 55–62
(January 2003); doi:10.1038/ni863
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review article Alternative activation of macrophages
Siamon Gordon Nature Reviews Immunology3, 23–35
(January 2003); doi:10.1038/nri978
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news and views Unmet expectations: The brain minds
William A. Carlezon Jr. and Roy A. Wise Nature Medicine9, 15–16
(January 2003); doi:10.1038/nm0103-15
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review article Scientific and therapeutic advances in antiplatelet therapy
Deepak L. Bhatt and Eric J. Topol Nature Reviews Drug Discovery2, 15–28
(January 2003); doi:10.1038/nrd985
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letters to nature Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
Hong Wang, Man Yu, Mahendar Ochani, Carol Ann Amella, Mahira Tanovic, Seenu Susarla, Jian Hua Li, Haichao Wang, Huan Yang, Luis Ulloa, Yousef Al-Abed, Christopher J. Czura and Kevin J. Tracey Nature421, 384–388
(23 January 2003); doi:10.1038/nature01339
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news and views Inflammation: A nervous connection
Claude Libert Nature421, 328–329
(23 January 2003); doi:10.1038/421328a
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news and views Neurobiology: Fear thou not
Yadin Dudai Nature421, 325–327
(23 January 2003); doi:10.1038/421325a
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review article Entry of viruses through the epithelial barrier: Pathogenic trickery
Morgane Bomsel and Annette Alfsen Nature Reviews Molecular Cell Biology4, 57–68
(January 2003); doi:10.1038/nrm1005
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review article The dual-function CD150 receptor subfamily: the viral attraction
Svetlana P. Sidorenko and Edward A. Clark Nature Immunology4, 19–24
(January 2003); doi:10.1038/ni0103-19
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article Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
Karen Lai, Brian K. Kaspar, Fred H. Gage and David V. Schaffer Nature Neuroscience6, 21–27
(January 2003); doi:10.1038/nn983
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review article Plasma membrane monoamine transporters: structure, regulation and function
Gonzalo E. Torres, Raul R. Gainetdinov and Marc G. Caron Nature Reviews Neuroscience4, 13–25
(January 2003); doi:10.1038/nrn1008
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letters to nature Coupling of agonist binding to channel gating in the GABAA receptor
Thomas L. Kash, Andrew Jenkins, Jill C. Kelley, James R. Trudell and Neil L. Harrison Nature421, 272–275
(16 January 2003); doi:10.1038/nature01280
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review article CD44: From adhesion molecules to signalling regulators
Helmut Ponta, Larry Sherman and Peter A. Herrlich Nature Reviews Molecular Cell Biology4, 33–45
(January 2003); doi:10.1038/nrm1004
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article IL-28, IL-29 and their class II cytokine receptor IL-28R
Paul Sheppard, Wayne Kindsvogel, Wenfeng Xu, Katherine Henderson, Stacy Schlutsmeyer, Theodore E. Whitmore, Rolf Kuestner, Ursula Garrigues, Carl Birks, Jenny Roraback, Craig Ostrander, Dennis Dong, Jinu Shin, Scott Presnell, Brian Fox, Betty Haldeman, Emily Cooper, David Taft, Teresa Gilbert, Francis J. Grant, Monica Tackett, William Krivan, Gary McKnight, Chris Clegg, Don Foster and Kevin M. Klucher Nature Immunology4, 63–68
(January 2003); doi:10.1038/ni873
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article IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex
Sergei V. Kotenko, Grant Gallagher, Vitaliy V. Baurin, Anita Lewis-Antes, Meiling Shen, Nital K. Shah, Jerome A. Langer, Faruk Sheikh, Harold Dickensheets and Raymond P. Donnelly Nature Immunology4, 69–77
(January 2003); doi:10.1038/ni875
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news and views Novel interferons
Jan Vilcek Nature Immunology4, 8–9
(January 2003); doi:10.1038/ni0103-8
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article Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Samuel Davis, Nick Papadopoulos, Thomas H. Aldrich, Peter C. Maisonpierre, Tammy Huang, Lubomir Kovac, April Xu, Raymond Leidich, Elzbieta Radziejewska, Ashique Rafique, Judah Goldberg, Vivek Jain, Kevin Bailey, Margaret Karow, Jim Fandl, Steven J. Samuelsson, Ella Ioffe, John S. Rudge, Thomas J. Daly, Czeslaw Radziejewski and George D. Yancopoulos Nature Structural Biology10, 38–44
(January 2003); doi:10.1038/nsb880
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letters to nature IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
Martin Holzenberger, Joëlle Dupont, Bertrand Ducos, Patricia Leneuve, Alain Géloën, Patrick C. Even, Pascale Cervera and Yves Le Bouc Nature421, 182–187
(09 January 2003); doi:10.1038/nature01298
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news and views Physiology: Cost-free longevity in mice?
Gordon J. Lithgow and Matthew S. Gill Nature421, 125–126
(09 January 2003); doi:10.1038/421125a
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review article Nongenomic actions of steroid hormones
Ralf Lösel and Martin Wehling Nature Reviews Molecular Cell Biology4, 46–55
(January 2003); doi:10.1038/nrm1009
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article A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
Siu Sylvia Lee, Raymond Y.N. Lee, Andrew G. Fraser, Ravi S. Kamath, Julie Ahringer and Gary Ruvkun Nature Genetics33, 40–48
(January 2003); doi:10.1038/ng1056
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article Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice
Stephan G. Anagnostaras, Geoffrey G. Murphy, Susan E. Hamilton, Scott L. Mitchell, Nancy P. Rahnama, Neil M. Nathanson and Alcino J. Silva Nature Neuroscience6, 51–58
(January 2003); doi:10.1038/nn992
| Abstract | Full Text (HTML/PDF) |
letters to nature Extinction-induced upregulation in AMPA receptors reduces cocaine-seeking behaviour
Michael A. Sutton, Eric F. Schmidt, Kwang-Ho Choi, Christina A. Schad, Kim Whisler, Diana Simmons, David A. Karanian, Lisa M. Monteggia, Rachael L. Neve and David W. Self Nature421, 70–75
(02 January 2003); doi:10.1038/nature01249
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letters to nature Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis
Laurent O. Martinez, Sébastien Jacquet, Jean-Pierre Esteve, Corinne Rolland, Elena Cabezón, Eric Champagne, Thierry Pineau, Valérie Georgeaud, John E. Walker, François Tercé, Xavier Collet, Bertrand Perret and Ronald Barbaras Nature421, 75–79
(02 January 2003); doi:10.1038/nature01250
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review article Viral mimicry of cytokines, chemokines and their receptors
Antonio Alcami Nature Reviews Immunology3, 36–50
(January 2003); doi:10.1038/nri980
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article Cytokine traps: multi-component, high-affinity blockers of cytokine action
Aris N. Economides, Laura Rocco Carpenter, John S. Rudge, Vivien Wong, Ellen M. Koehler-Stec, Christopher Hartnett, Erica A. Pyles, Xiaobing Xu, Thomas J. Daly, Michael R. Young, James P. Fandl, Frank Lee, Scott Carver, Jennifer McNay, Kevin Bailey, Swayampakula Ramakanth, Renta Hutabarat, Tammy T. Huang, Czeslaw Radziejewski, George D. Yancopoulos and Neil Stahl Nature Medicine9, 47–52
(January 2003); doi:10.1038/nm811
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news and views Setting the cytokine trap for autoimmunity
Charles A. Dinarello Nature Medicine9, 20–22
(January 2003); doi:10.1038/nm0103-20
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