letter NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
Ragnhildur Káradóttir, Pauline Cavelier, Linda H. Bergersen and David Attwell Nature438, 1162–1166
(22 December 2005); doi:10.1038/nature04302
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letter NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Michael G. Salter and Robert Fern Nature438, 1167–1171
(22 December 2005); doi:10.1038/nature04301
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news and views Apoptosis: eating sensibly
Christopher D. Gregory and Simon B. Brown Nature Cell Biology7, 1161–1163
(December 2005); doi:10.1038/ncb1205-1061
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article FARP2 triggers signals for Sema3A-mediated axonal repulsion
Toshihiko Toyofuku, Junko Yoshida, Tamiko Sugimoto, Hong Zhang, Atsushi Kumanogoh, Masatsugu Hori and Hitoshi Kikutani Nature Neuroscience8, 1712–1719
(December 2005); doi:10.1038/nn1596
| Abstract | Full Text (HTML/PDF) |
news and views Tinker to Evers to Chance: semaphorin signaling takes teamwork
Paul A Garrity Nature Neuroscience8, 1635–1636
(December 2005); doi:10.1038/nn1205-1635
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article A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control
Vadim Budagian, Elena Bulanova, Zane Orinska, Lutz Thon, Uwe Mamat1, Paola Bellosta, Claudio Basilico, Dieter Adam, Ralf Paus and Silvia Bulfone-Paus The EMBO Journal24, 4260–4270
(December 2005); doi:10.1038/sj.emboj.7600874
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letter BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Jeffrey A. M. Coull , Simon Beggs, Dominic Boudreau, Dominick Boivin, Makoto Tsuda, Kazuhide Inoue, Claude Gravel, Michael W. Salter and Yves De Koninck Nature438, 1017–1021
(15 December 2005); doi:10.1038/nature04223
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article Regulation of Notch signalling by non-visual β-arrestin
Ashim Mukherjee, Alexey Veraksa, Andreas Bauer, Carine Rosse, Jacques Camonis and Spyros Artavanis-Tsakonas Nature Cell Biology7, 1191–1201
(December 2005); doi:10.1038/ncb1327
| Abstract | Full Text (HTML/PDF) |
news and views Receptor regulation: β-arrestin moves up a notch
Sudha K. Shenoy & Robert J. Lefkowitz Nature Cell Biology7, 1159–1161
(December 2005); doi:10.1038/ncb1205-1059
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letter Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction
Gary Davidson, Wei Wu, Jinlong Shen, Josipa Bilic, Ursula Fenger, Peter Stannek, Andrei Glinka and Christof Niehrs Nature438, 867–872
(08 December 2005); doi:10.1038/nature04170
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letter A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
Xin Zeng, Keiko Tamai, Brad Doble, Shitao Li, He Huang, Raymond Habas, Heidi Okamura, Jim Woodgett and Xi He Nature438, 873–877
(08 December 2005); doi:10.1038/nature04185
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news and views Cell biology: Relays at the membrane
Roel Nusse Nature438, 747–749
(08 December 2005); doi:10.1038/438747a
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article mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression
Nathalie Sans, Philip Y. Wang, Quansheng Du, Ronald S. Petralia, Ya-Xian Wang, Sajan Nakka, Joe B. Blumer, Ian G. Macara and Robert J. Wenthold Nature Cell Biology7, 1179–1190
(December 2005); doi:10.1038/ncb1325
| Abstract | Full Text (HTML/PDF) |
news and views Pins for spines
Juergen A. Knoblich Nature Cell Biology7, 1157–1158
(December 2005); doi:10.1038/ncb1205-1057
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article The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
Chen Zhu, Ana C Anderson, Anna Schubart, Huabao Xiong, Jaime Imitola, Samia J Khoury, Xin Xiao Zheng, Terry B Strom and Vijay K Kuchroo Nature Immunology6, 1245–1252
(December 2005); doi:10.1038/ni1271
| Abstract | Full Text (HTML/PDF) |
brief communication Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
Torkel Vang, Mauro Congia, Maria Doloretta Macis, Lucia Musumeci, Valeria Orrú, Patrizia Zavattari, Konstantina Nika, Lutz Tautz, Kjetil Taskén, Francesco Cucca, Tomas Mustelin and Nunzio Bottini Nature Genetics37, 1317–1319
(December 2005); doi:10.1038/ng1673
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article Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
Tadashi Yokosuka, Kumiko Sakata-Sogawa, Wakana Kobayashi, Michio Hiroshima, Akiko Hashimoto-Tane, Makio Tokunaga, Michael L Dustin and Takashi Saito Nature Immunology6, 1253–1262
(December 2005); doi:10.1038/ni1272
| Abstract | Full Text (HTML/PDF) |
news and views Microclusters initiate and sustain T cell signaling
Alain Trautmann Nature Immunology6, 1213–1214
(December 2005); doi:10.1038/ni1205-1213
| Full Text (HTML/PDF) |
brief communication Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR
Daphne W Bell, Ira Gore, Ross A Okimoto, Nadia Godin-Heymann, Raffaella Sordella, Roseann Mulloy, Sreenath V Sharma, Brian W Brannigan, Gayatry Mohapatra, Jeff Settleman and Daniel A Haber Nature Genetics37, 1315–1316
(December 2005); doi:10.1038/ng1671
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article NMDA receptors regulate developmental gap junction uncoupling via CREB signaling
Harsha Arumugam, Xinhuai Liu, Paul J Colombo, Roderick A Corriveau and Andrei B Belousov Nature Neuroscience8, 1720–1726
(December 2005); doi:10.1038/nn1588
| Abstract | Full Text (HTML/PDF) |
news and views Flipping the switch from electrical to chemical communication
Karl Kandler and Edda Thiels Nature Neuroscience8, 1633–1634
(December 2005); doi:10.1038/nn1205-1633
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November
article Essential function for the kinase TAK1 in innate and adaptive immune responses
Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda, Jun Ninomiya-Tsuji, Masahiro Yamamoto, Taro Kawai, Kunihiro Matsumoto, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 1087–1095
(November 2005); doi:10.1038/ni1255
| Abstract | Full Text (HTML/PDF) |
article Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling
Stephen B Gauld, Robert J Benschop, Kevin T Merrell and John C Cambier Nature Immunology6, 1160–1167
(November 2005); doi:10.1038/ni1256
| Abstract | Full Text (HTML/PDF) |
article The initiation of antigen-induced B cell antigen receptor signaling viewed in living cells by fluorescence resonance energy transfer
Pavel Tolar, Hae Won Sohn and Susan K Pierce Nature Immunology6, 1168–1176
(November 2005); doi:10.1038/ni1262
| Abstract | Full Text (HTML/PDF) |
news and views Unraveling B cell receptor mechanics
Jürgen Wienands Nature Immunology6, 1072–1074
(November 2005); doi:10.1038/ni1105-1072
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letter Control of B-cell responses by Toll-like receptors
Chandrashekhar Pasare and Ruslan Medzhitov Nature438, 364–368
(17 November 2005); doi:10.1038/nature04267
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article Distinct enzyme combinations in AKAP signalling complexes permit functional diversity
Naoto Hoshi, Lorene K. Langeberg and John D. Scott Nature Cell Biology7, 1066–1073
(November 2005); doi:10.1038/ncb1315
| Abstract | Full Text (HTML/PDF) |
news and views A-kinase anchoring proteins: different partners, different dance
Lei Chen and Robert S. Kass Nature Cell Biology7, 1050–1051
(November 2005); doi:10.1038/ncb1105-1050
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article Essential function for the kinase TAK1 in innate and adaptive immune responses
Shintaro Sato, Hideki Sanjo, Kiyoshi Takeda, Jun Ninomiya-Tsuji, Masahiro Yamamoto, Taro Kawai, Kunihiro Matsumoto, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 1087–1095
(November 2005); doi:10.1038/ni1255
| Abstract | Full Text (HTML/PDF) |
article Regulation of lung injury and repair by Toll-like receptors and hyaluronan
Dianhua Jiang, Jiurong Liang, Juan Fan, Shuang Yu, Suping Chen, Yi Luo, Glenn D Prestwich, Marcella M Mascarenhas, Hari G Garg, Deborah A Quinn, Robert J Homer, Daniel R Goldstein, Richard Bucala, Patty J Lee, Ruslan Medzhitov and Paul W Noble Nature Medicine11, 1173–1179
(November 2005); doi:10.1038/nm1315
| Abstract | Full Text (HTML/PDF) |
news and views TLRs play good cop, bad cop in the lung
Luke A J O'Neill Nature Medicine11, 1161–1162
(November 2005); doi:10.1038/nm1105-1161
| Full Text (HTML/PDF) |
letter A quantitative protein interaction network for the ErbB receptors using protein microarrays
Richard B. Jones, Andrew Gordus, Jordan A. Krall and Gavin MacBeath NatureAdvance online publication
(6 November 2005); doi:10.1038/nature04177
| Abstract | Full Text (HTML / PDF) |
review article Fuel feeds function: energy metabolism and the T-cell response
Casey J. Fox , Peter S. Hammerman and Craig B. Thompson Nature Reviews Immunology5, 844–852
(November 2005); doi:10.1038/nri1710
| Summary | Full Text (HTML / PDF) |
letter Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
Robert S Ohgami, Dean R Campagna, Eric L Greer, Brendan Antiochos, Alice McDonald, Jing Chen, John J Sharp, Yuko Fujiwara, Jane E Barker and Mark D Fleming Nature Genetics37, 1264–1269
(November 2005); doi:10.1038/ng1658
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news and views A ferrireductase fills the gap in the transferrin cycle
Andrew T McKie Nature Genetics37, 1159–1160
(November 2005); doi:10.1038/ng1105-1159
| Full Text (HTML/PDF) |
review article Coordinating ERK/MAPK signaling through scaffolds and inhibitors
Walter Kolch Nature Reviews Molecular Cell Biology6, 827–837
(November 2005); doi:10.1038/nrm1743
| Abstract
| Full Text (HTML / PDF) |
news and views How neurons keep in touch
Fekrije Selimi and Nathaniel Heintz Nature Neuroscience8, 1417–1418
(November 2005); doi:10.1038/nn1105-1417
| Full Text (HTML / PDF) |
article Phosphorylation of ephrin-B1 via the interaction with claudin following cell–cell contact formation
Masamitsu Tanaka, Reiko Kamata and Ryuichi Sakai The EMBO Journal24, 3700–3711
(2 November 2005); doi:10.1038/sj.emboj.7600831
| Abstract
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October
letter Genetic isolation of transport signals directing cell surface expression
Sojin Shikano, Brian Coblitz, Haiyan Sun and Min Li Nature Cell Biology7, 985–992
(October 2005); doi:10.1038/ncb1297
| First Paragraph | Full Text (HTML/PDF) |
letter Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
Etienne Meylan, Joseph Curran, Kay Hofmann, Darius Moradpour, Marco Binder, Ralf Bartenschlager and Jürg Tschopp Nature437, 1167–1172
(20 October 2005); doi:10.1038/nature04193
| First Paragraph | Full Text (HTML / PDF) |
article Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor
Romain Roncagalli, James E R Taylor, Shaohua Zhang, Xiaochu Shi, Riyan Chen, Mario-Ernesto Cruz-Munoz, Luo Yin, Sylvain Latour and André Veillette Nature Immunology6, 1002–1010
(October 2005); doi:10.1038/ni1242
| Abstract | Full Text (HTML/PDF) |
news and views Fine-tuning NK cell responses: it's a family affair
Marco Colonna Nature Immunology6, 961–962
(October 2005); doi:10.1038/ni1005-961
| Full Text (HTML/PDF) |
article Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity
Jacques I Wadiche and Craig E Jahr Nature Neuroscience8, 1329–1334
(October 2005); doi:10.1038/nn1539
| Abstract | Full Text (HTML/PDF) |
letter Vertebrate Smoothened functions at the primary cilium
Kevin C. Corbit, Pia Aanstad , Veena Singla, Andrew R. Norman, Didier Y. R. Stainier and Jeremy F. Reiter Nature437, 1018–1021
(13 October 2005); doi:10.1038/nature04117
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review article Cell-surface enzymes in control of leukocyte trafficking
Marko Salmi and Sirpa Jalkanen Nature Reviews Immunology5, 760–771
(October 2005); doi:10.1038/nri1705
| Abstract | Full Text (HTML / PDF) |
article Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
Baohua Zhou, Michael R Comeau, Thibaut De Smedt, H Denny Liggitt, Martin E Dahl, David B Lewis, Dora Gyarmati, Theingi Aye, Daniel J Campbell and Steven F Ziegler Nature Immunology6, 1047–1053
(October 2005); doi:10.1038/ni1247
| Abstract | Full Text (HTML/PDF) |
article Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors
Guo-Min Deng, Lixin Zheng, Francis Ka-Ming Chan and Michael Lenardo Nature Medicine11, 1066–1072
(October 2005); doi:10.1038/nm1304
| Abstract | Full Text (HTML/PDF) |
review article Metabotropic glutamate receptors in the basal ganglia motor circuit
P. Jeffrey Conn, Giuseppe Battaglia, Michael J. Marino and Ferdinando Nicoletti Nature Reviews Neuroscience6, 787–798
(October 2005); doi:10.1038/nrn1763
| Abstract | Full Text (HTML / PDF) |
article Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
Petra Van Damme, Lennart Martens, Jozef Van Damme, Koen Hugelier, An Staes, Joël Vandekerckhove and Kris Gevaert Nature Methods2, 771–777
(October 2005); doi:10.1038/nmeth792
| Abstract | Full Text (HTML/PDF) |
September
letter Listeria hijacks the clathrin-dependent endocytic machinery to invade mammalian cells
Esteban Veiga and Pascale Cossart Nature Cell Biology7, 894–900
(September 2005); doi:10.1038/ncb1292
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article Model for growth hormone receptor activation based on subunit rotation within a receptor dimer
Richard J Brown, Julian J Adams, Rebecca A Pelekanos, Yu Wan, William J McKinstry, Kathryn Palethorpe, Ruth M Seeber, Thea A Monks, Karin A Eidne, Michael W Parker and Michael J Waters Nature Structural and Molecular Biology12, 814–821
(September 2005); doi:10.1038/nsmb977
| Abstract | Full Text (HTML/PDF) |
review article Pathophysiological consequences of VEGF-induced vascular permeability
Sara M. Weis and David A. Cheresh Nature437, 497–504
(22 September 2005); doi:10.1038/nature03987
| Abstract | Full Text (HTML / PDF) |
article Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance
David E Oppenheim, Scott J Roberts, Sarah L Clarke, Renata Filler, Julie M Lewis, Robert E Tigelaar, Michael Girardi and Adrian C Hayday Nature Immunology6, 928–937
(September 2005); doi:10.1038/ni1239
| Abstract | Full Text (HTML/PDF) |
letter LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
Eric Metzger, Melanie Wissmann, Na Yin, Judith M. Müller, Robert Schneider, Antoine H. F. M. Peters, Thomas Günther, Reinhard Buettner and Roland Schüle Nature437, 436–439
(15 September 2005); doi:10.1038/nature04020
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review article Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation
Warren J. Leonard and Rosanne Spolski Nature Reviews Immunology5, 688–698
(September 2005); doi:10.1038/nri1688
| Abstract | Full Text (HTML / PDF) |
letter Mutations in NOTCH1 cause aortic valve disease
Vidu Garg, Alecia N. Muth, Joshua F. Ransom, Marie K. Schluterman, Robert Barnes, Isabelle N. King , Paul D. Grossfeld and Deepak Srivastava Nature437, 270–274
(08 September 2005); doi:10.1038/nature03940
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article Notch promotes survival of pre-T cells at the β-selection checkpoint by regulating cellular metabolism
Maria Ciofani and Juan Carlos Zúñiga-Pflücker Nature Immunology6, 881–888
(September 2005); doi:10.1038/ni1234
| Abstract | Full Text (HTML/PDF) |
review article The Yin and Yang of type I interferon activity in bacterial infection
Thomas Decker, Mathias Müller and Silvia Stockinger Nature Reviews Immunology5, 675–687
(September 2005); doi:10.1038/nri1684
| Abstract | Full Text (HTML / PDF) |
article Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation
Xiaofeng Li, Peng Liu, Wenzhong Liu, Peter Maye, Jianghong Zhang, Yazhou Zhang, Marja Hurley, Caiying Guo, Adele Boskey, Le Sun, Stephen E Harris, David W Rowe, Hua Zhu Ke and Dianqing Wu Nature Genetics37, 945–952
(September 2005); doi:10.1038/ng1614
| Abstract | Full Text (HTML/PDF) |
August
article Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
Brendan J Jenkins, Dianne Grail, Thao Nheu, Meri Najdovska, Bo Wang, Paul Waring, Melissa Inglese, Rachel M McLoughlin, Simon A Jones, Nicholas Topley, Heinz Baumann, Louise M Judd, Andrew S Giraud, Alex Boussioutas, Hong-Jian Zhu and Matthias Ernst Nature Medicine11, 845–852
(August 2005); doi:10.1038/nm1282
| Abstract | Full Text (HTML/PDF) |
article Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach
Alexandre Lautrette, Shunqiang Li, Rohia Alili, Susan W Sunnarborg, Martine Burtin, David C Lee, Gérard Friedlander and Fabiola Terzi Nature Medicine11, 867–874
(August 2005); doi:10.1038/nm1275
| Abstract | Full Text (HTML/PDF) |
letter The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
Stephan Gasser, Sandra Orsulic, Eric J. Brown and David H. Raulet Nature436, 1186–1190
(25 August 2005); doi:10.1038/nature03884
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review article Functions and mechanisms of retrograde neurotrophin signalling
Larry S. Zweifel, Rejji Kuruvilla and David D. Ginty Nature Reviews Neuroscience6, 615–625
(August 2005); doi:10.1038/nrn1727
| Summary | Full Text (HTML / PDF) |
letter Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol
Harald W. Platta, Silke Grunau, Katja Rosenkranz, Wolfgang Girzalsky and Ralf Erdmann Nature Cell Biology7, 817–822
(August 2005); doi:10.1038/ncb1281
| First Paragraph | Full Text (HTML/PDF) |
article Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
Newton H Woo, Henry K Teng, Chia-Jen Siao, Cristina Chiaruttini, Petti T Pang, Teresa A Milner, Barbara L Hempstead and Bai Lu Nature Neuroscience8, 1069–1077
(August 2005); doi:10.1038/nn1510
| Abstract | Full Text (HTML/PDF) |
article Nonstimulatory peptides contribute to antigen-induced CD8-T cell receptor interaction at the immunological synapse
Pia P Yachi, Jeanette Ampudia, Nicholas R J Gascoigne and Tomasz Zal Nature Immunology6, 785–792
(August 2005); doi:10.1038/ni1220
| Abstract | Full Text (HTML/PDF) |
letter A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
Keiji Kuba, Yumiko Imai, Shuan Rao, Hong Gao, Feng Guo, Bin Guan, Yi Huan, Peng Yang, Yanli Zhang, Wei Deng, Linlin Bao, Binlin Zhang, Guang Liu, Zhong Wang, Mark Chappell, Yanxin Liu, Dexian Zheng, Andreas Leibbrandt, Teiji Wada, Arthur S Slutsky, Depei Liu, Chuan Qin, Chengyu Jiang and Josef M Penninger Nature Medicine11, 875–879
(August 2005); doi:10.1038/nm1267
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news and views Good ACE, bad ACE do battle in lung injury, SARS
John Nicholls and Malik Peiris Nature Medicine11, 821–822
(August 2005); doi:10.1038/nm0805-821
| Full Text (HTML/PDF) |
article Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
U Salzer, H M Chapel, A D B Webster, Q Pan-Hammarström, A Schmitt-Graeff, M Schlesier, H H Peter, J K Rockstroh, P Schneider, A A Schäffer, L Hammarström and B Grimbacher Nature Genetics37, 820–828
(August 2005); doi:10.1038/ng1600
| Abstract | Full Text (HTML/PDF) |
article TACI is mutant in common variable immunodeficiency and IgA deficiency
Emanuela Castigli, Stephen A Wilson, Lilit Garibyan, Rima Rachid, Francisco Bonilla, Lynda Schneider and Raif S Geha Nature Genetics37, 829–834
(August 2005); doi:10.1038/ng1601
| Abstract | Full Text (HTML/PDF) |
news and views Unraveling TACIt functions
Flavius Martin and Vishva M Dixit Nature Genetics37, 793–794
(August 2005); doi:10.1038/ng0805-793
| Full Text (HTML/PDF) |
article Regulation of NMDA receptor trafficking by amyloid-β
Eric M Snyder, Yi Nong, Claudia G Almeida, Surojit Paul, Timothy Moran, Eun Young Choi, Angus C Nairn, Michael W Salter, Paul J Lombroso, Gunnar K Gouras and Paul Greengard Nature Neuroscience8, 1051–1058
(August 2005); doi:10.1038/nn1503
| Abstract | Full Text (HTML/PDF) |
news and views The synaptic Aβ hypothesis of Alzheimer disease
Rudolph E Tanzi Nature Neuroscience8, 977–979
(August 2005); doi:10.1038/nn0805-977
| Full Text (HTML/PDF) |
review article The yin and yang of neurotrophin action
Bai Lu, Petti T. Pang and Newton H. Woo Nature Reviews Neuroscience6, 603–614
(August 2005); doi:10.1038/nrn1726
| Abstract | Full Text (HTML / PDF) |
letter Licensing of natural killer cells by host major histocompatibility complex class I molecules
Sungjin Kim, Jennifer Poursine-Laurent, Steven M. Truscott, Lonnie Lybarger, Yun-Jeong Song, Liping Yang, Anthony R. French, John B. Sunwoo, Suzanne Lemieux, Ted H. Hansen and Wayne M. Yokoyama Nature436, 709–713
(04 August 2005); doi:10.1038/nature03847
| First Paragraph | Full Text (HTML / PDF) |
article Protein kinase activity of phosphoinositide 3-kinase regulates β-adrenergic receptor endocytosis
Sathyamangla V. Naga Prasad, Arundathi Jayatilleke, Aasakiran Madamanchi and Howard A. Rockman Nature Cell Biology7, 785–796
(August 2005); doi:10.1038/ncb1278
| Abstract | Full Text (HTML/PDF) |
news and views Substrate specificity: PI(3)Kγ has it both ways
Jonathan M. Backer Nature Cell Biology7, 773–774
(August 2005); doi:10.1038/ncb0805-773
| Full Text (HTML/PDF) |
article Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
Giorgio Napolitani, Andrea Rinaldi, Francesco Bertoni, Federica Sallusto and Antonio Lanzavecchia Nature Immunology6, 769–776
(August 2005); doi:10.1038/ni1223
| Abstract | Full Text (HTML/PDF) |
news and views 'TaiLoRing' the response of dendritic cells to pathogens
Bernard Malissen and Jonathan J Ewbank Nature Immunology6, 749–750
(August 2005); doi:10.1038/ni0805-749
| Full Text (HTML/PDF) |
article Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
Michael Martin, Kunal Rehani, Richard S Jope and Suzanne M Michalek Nature Immunology6, 777–784
(August 2005); doi:10.1038/ni1221
| Abstract | Full Text (HTML/PDF) |
news and views GSK3: an in-Toll-erant protein kinase?
James R Woodgett and Pamela S Ohashi Nature Immunology6, 751–752
(August 2005); doi:10.1038/ni0805-751
| Full Text (HTML/PDF) |
article Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses
Wade Morishita, Helene Marie and Robert C Malenka Nature Neuroscience8, 1043–1050
(August 2005); doi:10.1038/nn1506
| Abstract | Full Text (HTML/PDF) |
review article The vagus nerve and the nicotinic anti-inflammatory pathway
Luis Ulloa Nature Reviews Drug Discovery4, 673–684
(August 2005); doi:10.1038/nrd1797
| Abstract | Full Text (HTML / PDF) |
July
article Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
Daniela Foti, Eusebio Chiefari, Monica Fedele, Rodolfo Iuliano, Leonardo Brunetti, Francesco Paonessa, Guidalberto Manfioletti, Fabrizio Barbetti, Arturo Brunetti, Carlo M Croce, Alfredo Fusco and Antonio Brunetti Nature Medicine11, 765–773
(July 2005); doi:10.1038/nm1254
| Abstract | Full Text (HTML/PDF) |
review article Neurosteroids: endogenous regulators of the GABAA receptor
Delia Belelli and Jeremy J. Lambert Nature Reviews Neuroscience6, 565–575
(July 2005); doi:10.1038/nrn1703
| Abstract | Full Text (HTML / PDF) |
letter EphrinB2 is the entry receptor
for Nipah virus, an emergent deadly paramyxovirus Oscar A. Negrete,
Ernest L. Levroney, Hector C. Aguilar, Andrea Bertolotti-Ciarlet, Ronen
Nazarian, Sara Tajyar and Benhur Lee Nature436,
401–405 (21 July 2005); doi:10.1038/nature03838 | First Paragraph |
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PDF) |
review article Heparan sulphate proteoglycans: the sweet side of
development Udo Häcker, Kent Nybakken and Norbert Perrimon Nature
Reviews Molecular Cell Biology6, 530–541 (July 2005);
doi:10.1038/nrm1681 | Abstract | Full Text (HTML /
PDF) |
review article Tuning immune responses: diversity and adaptation of the immunological synapse
Peter Friedl, Annemieke Th. den Boer and Matthias Gunzer Nature Reviews Immunology5, 532–545
(July 2005); doi:10.1038/nri1647
| Summary | Full Text (HTML / PDF) |
article GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking
Casper C Hoogenraad, Aaron D Milstein, Iryna M Ethell, Mark Henkemeyer and Morgan Sheng
Nature Neuroscience8, 906–915
(July 2005); doi:10.1038/nn1487
| Full Text (HTML/PDF) |
news and views EphB2 gets a GRIP on the dendritic arbor
Charu Misra and Edward B Ziff Nature Neuroscience8, 848–850
(July 2005); doi:10.1038/nn0705-848
| Full Text (HTML/PDF) |
June
letter Ephrin signalling controls brain size by regulating apoptosis of neural progenitors
Vanessa Depaepe, Nathalie Suarez-Gonzalez, Audrey Dufour, Lara Passante, Jessica A Gorski, Kevin R. Jones, Catherine Ledent and Pierre Vanderhaeghen Nature435, 1244–1250
(30 June 2005); doi:10.1038/nature03651
| First Paragraph | Full Text (HTML/PDF) |
review article Negative regulation of Toll-like receptor-mediated immune responses
Foo Y. Liew, Damo Xu, Elizabeth K. Brint and Luke A. J. O'Neill Nature Reviews Immunology5, 446–458
(June 2005); doi:10.1038/nri1630
| Abstract | Full Text (HTML / PDF) |
article Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor
Georgios Skiniotis, Martin J Boulanger, K Christopher Garcia and Thomas Walz Nature Structural and Molecular Biology12, 545–551
(June 2005); doi:10.1038/nsmb941
| Abstract | Full Text (HTML/PDF) |
news and views Bow to your partner for signaling
Heike M Hermanns, Gerhard Müller-Newen, Peter C Heinrich and Serge Haan Nature Structural and Molecular Biology12, 476–478
(June 2005); doi:10.1038/nsmb0605-476
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letter Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
Johan H. van Es, Marielle E. van Gijn, Orbicia Riccio, Maaike van den Born, Marc Vooijs, Harry Begthel, Miranda Cozijnsen, Sylvie Robine, Doug J. Winton, Freddy Radtke and Hans Clevers Nature435, 959–963
(16 June 2005); doi:10.1038/nature03659
| First Paragraph | Full Text (HTML / PDF) |
letter Notch signals control the fate of immature progenitor cells in the intestine
Silvia Fre, Mathilde Huyghe, Philippos Mourikis, Sylvie Robine, Daniel Louvard and Spyros Artavanis-Tsakonas Nature435, 964–968
(16 June 2005); doi:10.1038/nature03589
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review article Developmental Cell Biology: Eph receptor signalling casts a wide net on cell behaviour
Elena B. Pasquale Nature Reviews Molecular Cell Biology6, 462–475
(June 2005); doi:10.1038/nrm1662
| Summary | Full Text (HTML / PDF) |
article Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105
Senad Divanovic, Aurelien Trompette, Sowsan F Atabani, Rajat Madan, Douglas T Golenbock, Alberto Visintin, Robert W Finberg, Alexander Tarakhovsky, Stefanie N Vogel, Yasmine Belkaid, Evelyn A Kurt-Jones and Christopher L Karp Nature Immunology6, 571–578
(June 2005); doi:10.1038/ni1198
| Abstract | Full Text (HTML/PDF) |
article TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells
Stephan R Krutzik, Belinda Tan, Huiying Li, Maria Teresa Ochoa, Philip T Liu, Sarah E Sharfstein, Thomas G Graeber, Peter A Sieling, Yong-Jun Liu, Thomas H Rea, Barry R Bloom and Robert L Modlin Nature Medicine11, 653–660
(June 2005); doi:10.1038/nm1246
| Abstract | Full Text (HTML/PDF) |
article Epistasis between mouse Klra and major histocompatibility complex class I loci is associated with a new mechanism of natural killer cell-mediated innate resistance to cytomegalovirus infection
Marie-Pierre Desrosiers, Agnieszka Kielczewska, J-C Loredo-Osti, Sonia Girard Adam, Andrew P Makrigiannis, Suzanne Lemieux, Trung Pham, Melissa B Lodoen, Kenneth Morgan, Lewis L Lanier and Silvia M Vidal Nature Genetics37, 593–599
(June 2005); doi:10.1038/ng1564
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news and views Antiviral synergism
Mary Carrington Nature Genetics37, 565–566
(June 2005); doi:10.1038/ng0605-565
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article XTRPC1-dependent chemotropic guidance of neuronal growth cones
Sangwoo Shim, Eyleen L Goh, Shaoyu Ge, Kurt Sailor, Joseph P Yuan, H Llewelyn Roderick, Martin D Bootman, Paul F Worley, Hongjun Song and Guo-li Ming Nature Neuroscience8, 730–735
(June 2005); doi:10.1038/nn1459
| Abstract | Full Text (HTML/PDF) |
review article Autophagy in metazoans: cell survival in the land of plenty
Julian J. Lum, Ralph J. DeBerardinis and Craig B. Thompson Nature Reviews Molecular Cell Biology6, 439–448
(June 2005); doi:10.1038/nrm1660
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article Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
Jessica A Hamerman, Nadia K Tchao, Clifford A Lowell and Lewis L Lanier Nature Immunology6, 579–586
(June 2005); doi:10.1038/ni1204
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article SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability
Narendrakumar Ramanan, Ying Shen, Sarah Sarsfield, Thomas Lemberger, Günther Schütz, David J Linden and David D Ginty Nature Neuroscience8, 759–767
(June 2005); doi:10.1038/nn1462
| Abstract | Full Text (HTML/PDF) |
review article Notch signaling in the mammalian central nervous system: insights from mouse mutants
Keejung Yoon and Nicholas Gaiano Nature Neuroscience8, 709–715
(June 2005); doi:10.1038/nn1475
| Abstract | Full Text (HTML/PDF) |
May
article The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium
Junlin Teng, Tatemitsu Rai, Yosuke Tanaka, Yosuke Takei, Takao Nakata, Motoyuki Hirasawa, Ashok B. Kulkarni and Nobutaka Hirokawa Nature Cell Biology7, 474–482
(May 2005); doi:10.1038/ncb1249
| Abstract | Full Text (HTML/PDF) |
news and views When domestiques rebel: kinesins, cadherins and neuronal proliferation
Cara J. Gottardi, Nicole R. den Elzen and Alpha S. Yap Nature Cell Biology7, 445–447
(May 2005); doi:10.1038/ncb0505-445
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article T cell costimulation by chemokine receptors
Barbara Molon, Giorgia Gri, Monica Bettella, Concepción Gómez-Moutón, Antonio Lanzavecchia, Carlos Martínez-A, Santos Mañes and Antonella Viola Nature Immunology6, 465–471
(May 2005); doi:10.1038/ni1191
| Abstract | Full Text (HTML/PDF) |
letter Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
Matias Simons, Joachim Gloy, Athina Ganner, Axel Bullerkotte, Mikhail Bashkurov, Corinna Krönig, Bernhard Schermer, Thomas Benzing, Olga A Cabello, Andreas Jenny, Marek Mlodzik, Bozena Polok, Wolfgang Driever, Tomoko Obara and Gerd Walz Nature Genetics37, 537–543
(May 2005); doi:10.1038/ng1552
| First Paragraph | Full Text (HTML/PDF) |
news and views Linking cilia to Wnts
Gregory G Germino Nature Genetics37, 455–457
(May 2005); doi:10.1038/ng0505-455
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article Asymmetric membrane ganglioside sialidase activity specifies axonal fate
Jorge Santos Da Silva, Takafumi Hasegawa, Taeko Miyagi, Carlos G Dotti and Jose Abad-Rodriguez Nature Neuroscience8, 606–615
(May 2005); doi:10.1038/nn1442
| Abstract | Full Text (HTML/PDF) |
news and views Axon formation: fate versus growth
Hui Jiang and Yi Rao Nature Neuroscience8, 544–546
(May 2005); doi:10.1038/nn0505-544
| Full Text (HTML/PDF) |
letter The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity
Mitsuru Morimoto, Yu Takahashi, Maho Endo and Yumiko Saga Nature435, 354–359
(19 May 2005); doi:10.1038/nature03591
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article Inhibition of the NKp30 activating receptor by pp65 of human cytomegalovirus
Tal I Arnon, Hagit Achdout, Ofer Levi, Gal Markel, Nivin Saleh, Gil Katz, Roi Gazit, Tsufit Gonen-Gross, Jacob Hanna, Efrat Nahari, Angel Porgador, Alik Honigman, Bodo Plachter, Dror Mevorach, Dana G Wolf and Ofer Mandelboim Nature Immunology6, 515–523
(May 2005); doi:10.1038/ni1190
| Abstract | Full Text (HTML/PDF) |
article Lactadherin promotes VEGF-dependent neovascularization
Jean-Sébastien Silvestre, Clotilde Théry, Ghislaine Hamard, Jacques Boddaert, Barbara Aguilar, Alain Delcayre, Christophe Houbron, Radia Tamarat, Olivier Blanc-Brude, Sylvia Heeneman, Michel Clergue, Micheline Duriez, Régine Merval, Bernard Lévy, Alain Tedgui, Sebastian Amigorena and Ziad Mallat Nature Medicine11, 499–506
(May 2005); doi:10.1038/nm1233
| Abstract | Full Text (HTML/PDF) |
review article ERBB receptors and cancer: the complexity of targeted inhibitors
Nancy E. Hynes and Heidi A. Lane Nature Reviews Cancer5, 341–354
(May 2005); doi:10.1038/nrc1609
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article Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo
Yasuhiko Kawakami, Ángel Raya, R. Marina Raya, Concepción Rodríguez-Esteban and Juan Carlos Izpisúa Belmonte Nature435, 165–171
(12 May 2005); doi:10.1038/nature03512
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news and views Developmental biology: Asymmetrical threat averted
Eran Hornstein and Clifford J. Tabin Nature435, 155–156
(12 May 2005); doi:10.1038/435155a
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article FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
Yosuke Tanaka, Yasushi Okada and Nobutaka Hirokawa Nature435, 172–177
(12 May 2005); doi:10.1038/nature03494
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letters to nature Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos
Julien Vermot and Olivier Pourquié ′Nature435, 215–220
(12 May 2005); doi:10.1038/nature03488
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article Egr-2 and Egr-3 are negative regulators of T cell activation
Meredith Safford, Samuel Collins, Michael A Lutz, Amy Allen, Ching-Tai Huang, Jeanne Kowalski, Amanda Blackford, Maureen R Horton, Charles Drake, Ronald H Schwartz and Jonathan D Powell Nature Immunology6, 472–480
(May 2005); doi:10.1038/ni1193
| Abstract | Full Text (HTML/PDF) |
review article Mechanisms of type-I- and type-II-interferon-mediated signalling
Leonidas C. Platanias Nature Reviews Immunology5, 375–386
(May 2005); doi:10.1038/nri1604
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news and views Do-all receptor takes on coagulation, inflammation
Charles Esmon Nature Medicine11, 475–477
(May 2005); doi:10.1038/nm0505-475
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review article WNTS in the vertebrate nervous system: from patterning to neuronal connectivity
Lorenza Ciani and Patricia C. Salinas Nature Reviews Neuroscience6, 351–362
(May 2005); doi:10.1038/nrn1665
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article Lipoprotein particles are required for Hedgehog and Wingless signalling
Daniela Panáková, Hein Sprong, Eric Marois, Christoph Thiele and Suzanne Eaton Nature435, 58–65
(05 May 2005); doi:10.1038/nature03504
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news and views Developmental biology: Morphogens hitch a greasy ride
Richard S. Mann and Joaquim Culi Nature435, 30–33
(05 May 2005); doi:10.1038/435030a
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letters to nature Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
Li-Ru You, Fu-Jung Lin, Christopher T. Lee, Francesco J. DeMayo, Ming-Jer Tsai and Sophia Y. Tsai Nature435, 98–104
(05 May 2005); doi:10.1038/nature03511
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review article A new self: MHC-class-I-independent Natural-killer-cell self-tolerance
Vinay Kumar and Megan E. McNerney Nature Reviews Immunology5, 363–374
(May 2005); doi:10.1038/nri1603
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article Ceramide upregulation causes pulmonary cell apoptosis and emphysema-like disease in mice
Irina Petrache, Viswanathan Natarajan, Lijie Zhen, Terry R Medler, Amy T Richter, Chung Cho, Walter C Hubbard, Evgeny V Berdyshev and Rubin M Tuder Nature Medicine11, 491–498
(June 2005); doi:10.1038/nm1238
| Abstract | Full Text (HTML/PDF) |
article The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids
Jean-Michel Revest, Francesco Di Blasi, Pierre Kitchener, Françoise Rougé-Pont, Aline Desmedt, Marc Turiault, François Tronche and Pier Vincenzo Piazza Nature Neuroscience8, 664–672
(May 2005); doi:10.1038/nn1441
| Abstract | Full Text (HTML/PDF) |
news and views Lipid let loose in pulmonary emphysema
Jack A Elias and Chun Geun Lee Nature Medicine11, 471–472
(May 2005); doi:10.1038/nm0505-471
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April
article Immune activation modulates hematopoiesis through interactions between CD27 and CD70
Martijn A Nolte, Ramon Arens, Ronald van Os, Michiel van Oosterwijk, Berend Hooibrink, René A W van Lier and Marinus H J van Oers Nature Immunology6, 412–418
(April 2005); doi:10.1038/ni1174
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article The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis
Teiji Wada, Tomoki Nakashima, Antonio J Oliveira-dos-Santos, Juerg Gasser, Hiromitsu Hara, Georg Schett and Josef M Penninger Nature Medicine11, 394–399
(April 2005); doi:10.1038/nm1203
| Abstract | Full Text (HTML/PDF) |
letter Wnt signalling induces maturation of Paneth cells in intestinal crypts
Johan H. van Es, Philippe Jay, Alex Gregorieff, Marielle E. van Gijn, Suzanne Jonkheer, Pantelis Hatzis, Andrea Thiele, Maaike van den Born, Harry Begthel, Thomas Brabletz, Makoto M. Taketo and Hans Clevers Nature Cell Biology7, 381–386
(April 2005); doi:10.1038/ncb1240
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news and views MET orchestrates cancer and blood coagulation
Olga I Stenina and Edward F Plow Nature Medicine11, 376–377
(April 2005); doi:10.1038/nm0405-376
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article Drosophila N-cadherin mediates an attractive interaction between photoreceptor axons and their targets
Saurabh Prakash, Jason C Caldwell, Daniel F Eberl and Thomas R Clandinin Nature Neuroscience8, 443–450
(April 2005); doi:10.1038/nn1415
| Abstract | Full Text (HTML/PDF) |
news and views Photoreceptor axons play hide and seek
Javier Morante and Claude Desplan Nature Neuroscience8, 401–402
(April 2005); doi:10.1038/nn0405-401
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article Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
Edward J McManus, Kei Sakamoto, Laura J Armit, Leah Ronaldson, Natalia Shpiro, Rodolfo Marquez and Dario R Alessi The EMBO Journal24, 1571–1583
(April 2005); doi:10.1038/7600633a
| Abstract | Full Text (HTML/PDF) |
letters to nature Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor
Yan Li , Yi-Chang Jia , Kai Cui , Ning Li, Zai-Yu Zheng, Yi-zheng Wang and Xiao-bing Yuan Nature434, 894–898
(14 April 2005); doi:10.1038/nature03477
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letters to nature Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones
Gordon X. Wang and Mu-ming Poo Nature434, 898–904
(14 April 2005); doi:10.1038/nature03478
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news and views Neurobiology: Channels for pathfinding
Timothy Gomez Nature434, 835–838
(14 April 2005); doi:10.1038/434835a
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review article Wnt signalling in stem cells and cancer
Tannishtha Reya and Hans Clevers Nature434, 843–850
(14 April 2005); doi:10.1038/nature03319
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review article Developmental Cell Biology: Communicating with Hedgehogs
Joan E. Hooper and Matthew P. Scott Nature Reviews Molecular Cell Biology6, 306–317
(April 2005); doi:10.1038/nrm1612
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article Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases
Jesus M Salvador, Paul R Mittelstadt, Tad Guszczynski, Terry D Copeland, Hiroshi Yamaguchi, Ettore Appella, Albert J Fornace and Jr Jonathan D Ashwell Nature Immunology6, 390–395
(April 2005); doi:10.1038/ni1177
| Abstract | Full Text (HTML/PDF) |
article The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway
Jesus M Salvador, Paul R Mittelstadt, Galina I Belova, Albert J Fornace and Jr Jonathan D Ashwell Nature Immunology6, 396–402
(April 2005); doi:10.1038/ni1176
| Abstract | Full Text (HTML/PDF) |
news and views MAPK p38: alternative and nonstressful in T cells
Christopher E Rudd Nature Immunology6, 368–370
(April 2005); doi:10.1038/ni0405-368
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review article Mechanisms of suppression by suppressor T cells
Harald von Boehmer Nature Immunology6, 338–344
(April 2005); doi:10.1038/ni1180
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article Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
Jingmei Lin, Sanjeevkumar R Patel, Xu Cheng, Eun Ah Cho, Inna Levitan, Matthew Ullenbruch, Sem H Phan, John M Park and Gregory R Dressler Nature Medicine11, 387–393
(April 2005); doi:10.1038/nm1217
| Abstract | Full Text (HTML/PDF) |
news and views Setting a trap for tissue fibrosis
Eric G Neilson Nature Medicine11, 373–374
(April 2005); doi:10.1038/nm0405-373
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news and views The shear stress of keeping arteries clear
David G Harrison Nature Medicine11, 375–376
(April 2005); doi:10.1038/nm0405-375
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article Protocadherin Celsr3 is crucial in axonal tract development
Fadel Tissir, Isabelle Bar, Yves Jossin and Andre M Goffinet Nature Neuroscience8, 451–457
(April 2005); doi:10.1038/nn1428
| Abstract | Full Text (HTML/PDF) |
article The chemokine receptor D6 limits the inflammatory response in vivo
Thomas Jamieson, Donald N Cook, Robert J B Nibbs, Antal Rot, Colin Nixon, Pauline Mclean, Antonio Alcami, Sergio A Lira, Maria Wiekowski and Gerard J Graham Nature Immunology6, 403–411
(April 2005); doi:10.1038/ni1182
| Abstract | Full Text (HTML/PDF) |
news and views Inflammatory chemokines: tuned in, turned on, dropped out
Craig Gerard Nature Immunology6, 366–368
(April 2005); doi:10.1038/ni0405-366
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letter A chimeric human-cat fusion protein blocks cat-induced allergy
Daocheng Zhu, Christopher L Kepley, Ke Zhang, Tetsuya Terada, Takechiyo Yamada and Andrew Saxon Nature Medicine11, 446–449
(April 2005); doi:10.1038/nm1219
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news and views Nipping cat allergy with fusion proteins
Janet Kalesnikoff and Stephen J Galli Nature Medicine11, 381–382
(April 2005); doi:10.1038/nm0405-381
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review article Insights into host responses against pathogens from transcriptional profiling
Richard G. Jenner and Richard A. Young Nature Reviews Microbiology3, 281–294
(April 2005); doi:10.1038/nrmicro1126
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article Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance
Andrew W Duncan, Frédérique M Rattis, Leah N DiMascio, Kendra L Congdon, Gregory Pazianos, Chen Zhao, Keejung Yoon, J Michael Cook, Karl Willert, Nicholas Gaiano and Tannishtha Reya Nature Immunology6, 314–322
(March 2005); doi:10.1038/ni1164
| Abstract | Full Text (HTML/PDF) |
news and views Defining 'stemness': Notch and Wnt join forces?
Sten Eirik W Jacobsen Nature Immunology6, 234–236
(March 2005); doi:10.1038/ni0305-234
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article Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord
Dimitris Bourikas, Vladimir Pekarik, Thomas Baeriswyl, Åsa Grunditz, Rejina Sadhu, Michele Nardó and Esther T Stoeckli Nature Neuroscience8, 297–304
(March 2005); doi:10.1038/nn1396
| Abstract | Full Text (HTML/PDF) |
March
letters to nature Recognition of bacterial glycosphingolipids by natural killer T cells
Yuki Kinjo, Douglass Wu, Gisen Kim, Guo-Wen Xing, Michael A. Poles, David D. Ho, Moriya Tsuji, Kazuyoshi Kawahara, Chi-Huey Wong and Mitchell Kronenberg Nature434, 520–525
(24 March 2005); doi:10.1038/nature03407
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letters to nature Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections
Jochen Mattner, Kristin L. DeBord, Nahed Ismail, Randal D. Goff, Carlos Cantu III, Dapeng Zhou, Pierre Saint-Mezard, Vivien Wang, Ying Gao, Ning Yin, Kasper Hoebe, Olaf Schneewind, David Walker, Bruce Beutler, Luc Teyton, Paul B. Savage and Albert Bendelac Nature434, 525–529
(24 March 2005); doi:10.1038/nature03408
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article A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent
Mona K Tewari, Gomathinayagam Sinnathamby, Deepa Rajagopal and Laurence C Eisenlohr Nature Immunology6, 287–294
(March 2005); doi:10.1038/ni1171
| Abstract | Full Text (HTML/PDF) |
article G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes
Mutsuo Harada, Yingjie Qin, Hiroyuki Takano, Tohru Minamino, Yunzeng Zou, Haruhiro Toko, Masashi Ohtsuka, Katsuhisa Matsuura, Masanori Sano, Jun-ichiro Nishi, Koji Iwanaga, Hiroshi Akazawa, Takeshige Kunieda, Weidong Zhu, Hiroshi Hasegawa, Keita Kunisada, Toshio Nagai, Haruaki Nakaya, Keiko Yamauchi-Takihara and Issei Komuro Nature Medicine11, 305–311
(March 2005); doi:10.1038/nm1199
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article Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4
Hans Christian Probst, Kathy McCoy, Taku Okazaki, Tasuku Honjo and Maries van den Broek Nature Immunology6, 280–286
(March 2005); doi:10.1038/ni1165
| Abstract | Full Text (HTML/PDF) |
news and views Dendritic cells giveth and taketh away
Abul K Abbas and Arlene H Sharpe Nature Immunology6, 227–228
(March 2005); doi:10.1038/ni0305-227
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article The fibrin-derived peptide Bb15-42 protects the myocardium against ischemia-reperfusion injury
Peter Petzelbauer, Paula A Zacharowski, Yasuhiro Miyazaki, Peter Friedl, Georg Wickenhauser, Francis J Castellino, Marion Gröger, Klaus Wolff and Kai Zacharowski Nature Medicine11, 298–304
(March 2005); doi:10.1038/nm1198
| Abstract | Full Text (HTML/PDF) |
letter Conservation and diversification of Wnt signaling function during the evolution of nematode vulva development
Min Zheng, Daniel Messerschmidt, Benno Jungblut and Ralf J Sommer Nature Genetics37, 300–304
(March 2005); doi:10.1038/ng1512
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article Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells
Ren-He Xu, Ruthann M Peck, Dong S Li, Xuezhu Feng, Tenneille Ludwig and James A Thomson Nature Methods2, 185–190
(March 2005); doi:10.1038/nmeth744
| Abstract | Full Text (HTML/PDF) |
news and views Stem cell culture, one step at a time
Martin F Pera Nature Methods2, 164–165
(March 2005); doi:10.1038/nmeth0305-164
| Abstract | Full Text (HTML/PDF) |
letters to nature Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning
Yu-Chiun Wang and Edwin L. Ferguson Nature434, 229–234
(10 March 2005); doi:10.1038/nature03318
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letters to nature Agonist/endogenous peptide-MHC heterodimers drive T cell activation and sensitivity
Michelle Krogsgaard, Qi-jing Li, Cenk Sumen, Johannes B. Huppa, Morgan Huse and Mark M. Davis Nature434, 238–243
(10 March 2005); doi:10.1038/nature03391
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letters to nature Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
Akinori Takaoka, Hideyuki Yanai, Seiji Kondo, Gordon Duncan, Hideo Negishi, Tatsuaki Mizutani, Shin-ichi Kano, Kenya Honda, Yusuke Ohba, Tak W. Mak and Tadatsugu Taniguchi Nature434, 243–249
(10 March 2005); doi:10.1038/nature03308
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review article MHC class I molecules and kirs in human history, health and survival
Peter Parham Nature Reviews Immunology AOP published online 18 February 2005; doi:10.1038/nri1570
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review article Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
Mark Farrant and Zoltan Nusser Nature Reviews Neuroscience6, 215–229
(March 2005); doi:10.1038/nrn1625
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letters to nature Cross-presentation by intercellular peptide transfer through gap junctions
Joost Neijssen, Carla Herberts, Jan Wouter Drijfhout, Eric Reits, Lennert Janssen and Jacques Neefjes Nature434, 83–88
(03 March 2005); doi:10.1038/nature03290
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news and views Coupling and cross-presentation
William R. Heath and Francis R. Carbone Nature434, 27–28
(03 March 2005); doi:10.1038/434027a
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letters to nature CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death
Edith M. Janssen, Nathalie M. Droin, Edward E. Lemmens, Michael J. Pinkoski, Steven J. Bensinger, Benjamin D. Ehst, Thomas S. Griffith, Douglas R. Green and Stephen P. Schoenberger Nature434, 88–93
(03 March 2005); doi:10.1038/nature03337
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article Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
Veit Hornung, Margit Guenthner-Biller, Carole Bourquin, Andrea Ablasser, Martin Schlee, Satoshi Uematsu, Anne Noronha, Muthiah Manoharan, Shizuo Akira, Antonin de Fougerolles, Stefan Endres and Gunther Hartmann Nature Medicine11, 263–270
(March 2005); doi:10.1038/nm1191
| Abstract | Full Text (HTML/PDF) |
news and views Sensing the danger in RNA
Marjorie A Robbins and John J Rossi Nature Medicine11, 250–251
(March 2005); doi:10.1038/nm0305-250
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letter A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2
Bart L Loeys, Junji Chen, Enid R Neptune, Daniel P Judge, Megan Podowski, Tammy Holm, Jennifer Meyers, Carmen C Leitch, Nicholas Katsanis, Neda Sharifi, F Lauren Xu, Loretha A Myers, Philip J Spevak, Duke E Cameron, Julie De Backer, Jan Hellemans, Yan Chen, Elaine C Davis, Catherine L Webb, Wolfram Kress, Paul Coucke, Daniel B Rifkin, Anne M De Paepe and Harry C Dietz Nature Genetics37, 275–281
(March 2005); doi:10.1038/ng1511
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February
letters to nature Toll-like receptor 3 promotes cross-priming to virus-infected cells
Oliver Schulz, Sandra S. Diebold, Margaret Chen, Tanja I. Näslund, Martijn A. Nolte, Lena Alexopoulou, Yasu-Taka Azuma, Richard A. Flavell, Peter Liljeström and Caetano Reis e Sousa Nature433, 887–892
(24 February 2005); doi:10.1038/nature03326
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news and views Human immunodeficiency virus: Refolding the envelope
Peter D. Kwong Nature433, 815–816
(24 February 2005); doi:10.1038/433815a
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article Downregulation of natural killer cell-activating ligand CD155 by human cytomegalovirus UL141
Peter Tomasec, Eddie C Y Wang, Andrew J Davison, Borivoj Vojtesek, Melanie Armstrong, Cora Griffin, Brian P McSharry, Rebecca J Morris, Sian Llewellyn-Lacey, Carole Rickards, Akio Nomoto, Christian Sinzger and Gavin W G Wilkinson Nature Immunology6, 181–188
(February 2005); doi:10.1038/ni1156
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letters to nature Rejuvenation of aged progenitor cells by exposure to a young systemic environment
Irina M. Conboy , Michael J. Conboy, Amy J. Wagers, Eric R. Girma, Irving L. Weissman and Thomas A. Rando Nature433, 760–764
(17 February 2005); doi:10.1038/nature03260
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article CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
Xuguang Tai, Michelle Cowan, Lionel Feigenbaum and Alfred Singer Nature Immunology6, 152–162
(February 2005); doi:10.1038/ni1160
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article An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
Hideki Kizawa, Ikuyo Kou, Aritoshi Iida, Akihiro Sudo, Yoshinari Miyamoto, Akira Fukuda, Akihiko Mabuchi, Akihiro Kotani, Akira Kawakami, Seizo Yamamoto, Atsumasa Uchida, Kozo Nakamura, Kohei Notoya, Yusuke Nakamura and Shiro Ikegawa Nature Genetics37, 138–144
(February 2005); doi:10.1038/ng1496
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article Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation
Michael Piper, Saif Salih, Christine Weinl, Christine E Holt and William A Harris Nature Neuroscience8, 179–186
(February 2005); doi:10.1038/nn1380
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article Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivo
Brent A Hanks, Jianghong Jiang, Rana A K Singh, Weitao Song, Michael Barry, Mary H Huls, Kevin M Slawin and David M Spencer Nature Medicine11, 130–137
(February 2005); doi:10.1038/nm1183
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article Accelerated re-epithelialization in β3-integrin-deficient- mice is associated with enhanced TGF-β1 signaling
L E Reynolds, F J Conti, M Lucas, R Grose, S Robinson, M Stone, G Saunders, C Dickson, R O Hynes, A Lacy-Hulbert and K Hodivala-Dilke Nature Medicine11, 167–174
(February 2005); doi:10.1038/nm1165
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article Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
Yuanyuan Ji, Petti T Pang, Linyin Feng and Bai Lu Nature Neuroscience8, 164–172
(February 2005); doi:10.1038/nn1381
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letters to nature CD36 is a sensor of diacylglycerides
Kasper Hoebe, Philippe Georgel, Sophie Rutschmann, Xin Du, Suzanne Mudd, Karine Crozat, Sosathya Sovath, Louis Shamel, Thomas Hartung, Ulrich Zähringer and Bruce Beutler Nature433, 523–527
(03 February 2005); doi:10.1038/nature03253
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review article The tetraspanin web modulates immune-signalling complexes
Shoshana Levy and Tsipi Shoham Nature Reviews Immunology5, 136–148
(February 2005); doi:10.1038/nri1548
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letter Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2
Louise A Metherell, J Paul Chapple, Sadani Cooray, Alessia David, Christian Becker, Franz Rüschendorf, Danielle Naville, Martine Begeot, Bernard Khoo, Peter Nürnberg, Angela Huebner, Michael E Cheetham and Adrian J L Clark Nature Genetics37, 166–170
(February 2005); doi:10.1038/ng1501
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article Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo
Krystyna Keleman, Carlos Ribeiro and Barry J Dickson Nature Neuroscience8, 156–163
(February 2005); doi:10.1038/nn1388
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news and views Comm-ing across the midline
Catherine E Krull Nature Neuroscience8, 131–132
(February 2005); doi:10.1038/nn0205-131
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January
review article α-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles
Luc Van Kaer Nature Reviews Immunology5, 31–42
(January 2005); doi:10.1038/nri1531
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article Viral modulation of NK cell immunity
Melissa B. Lodoen and Lewis L. Lanier Nature Reviews Microbiology3, 59–69
(January 2005); doi:10.1038/nrmicro1066
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review article ADAMs: key components in EGFR signalling and development
Carl P. Blobel Nature Reviews Molecular Cell Biology6, 32–43
(January 2005); doi:10.1038/nrm1548
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article Dendritic epidermal T cells regulate skin homeostasis through local production of insulin-like growth factor 1
Leslie L Sharp, Julie M Jameson, Gabrielle Cauvi and Wendy L Havran Nature Immunology6, 73–79
(January 2005); doi:10.1038/ni1152
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article Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton
Mira Barda-Saad, Alex Braiman, Rachel Titerence, Stephen C Bunnell, Valarie A Barr and Lawrence E Samelson Nature Immunology6, 80–89
(January 2005); doi:10.1038/ni1143
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brief communication Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster
Ammon B Corl, Aylin R Rodan and Ulrike Heberlein Nature Neuroscience8, 18–19
(January 2005); doi:10.1038/nn1363
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review article LPS, TLR4 and infectious disease diversity
Samuel I. Miller, Robert K. Ernst and Martin W. Bader Nature Reviews Microbiology3, 36–46
(January 2005); doi:10.1038/nrmicro1068
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letter Negative regulation of EGFR signalling through integrin-α1β1-mediated activation of protein tyrosine phosphatase TCPTP
Elina Mattila, Teijo Pellinen, Jonna Nevo, Karoliina Vuoriluoto, Antti Arjonen and Johanna Ivaska Nature Cell Biology7, 78–85
(January 2005); doi:10.1038/ncb1209
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letter Drosophila Smoothened phosphorylation sites essential for Hedgehog signal transduction
Sergey Apionishev, Natalya M. Katanayeva, Steven A. Marks, Daniel Kalderon and Andrew Tomlinson Nature Cell Biology7, 86–92
(January 2005); doi:10.1038/ncb1210
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review article WNT signalling and haematopoiesis: a WNT-WNT situation
Frank J.T. Staal and Hans C. Clevers Nature Reviews Immunology5, 21–30
(January 2005); doi:10.1038/nri1529
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letter EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output
Peleg Hasson, Nirit Egoz, Clint Winkler, Gloria Volohonsky, Songtao Jia, Tama Dinur, Talila Volk, Albert J Courey and Ze'ev Paroush Nature Genetics37, 101–105
(January 2005); doi:10.1038/ng1486
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brief communication Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster
Eva M Neuhaus, Günter Gisselmann, Weiyi Zhang, Ruth Dooley, Klemens Störtkuhl and Hanns Hatt Nature Neuroscience8, 15–17
(January 2005); doi:10.1038/nn1371
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