letter Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity
Rongsheng Jin, Andreas Rummel, Thomas Binz and Axel T. Brunger Nature444, 10921095
(21 December 2006); doi:10.1038/nature05387
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letter Structural basis of cell surface receptor recognition by botulinum neurotoxin B
Qing Chai, Joseph W. Arndt, Min Dong, William H. Tepp, Eric A. Johnson, Edwin R. Chapman and Raymond C. Stevens Nature444, 10961100
(21 December 2006); doi:10.1038/nature05411
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review Membrane-protein topology
Gunnar von Heijne Nature Reviews Molecular Cell Biology7, 909918
(December 2006); doi:10.1038/nrm2063
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review Tuning inflammation and immunity by chemokine sequestration: decoys and more
Alberto Mantovani, Raffaella Bonecchi and Massimo Locati Nature Reviews Immunology7, 907918
(December 2006); doi:10.1038/nri1964
| Summary | Full Text (HTML / PDF) |
news and analysis Panitumumab
Leonard Saltz, Chris Easley and Peter Kirkpatrick Nature Reviews Drug Discovery5, 987988
(December 2006); doi:10.1038/nrd2204
| Summary | Full Text (HTML / PDF) |
article A diacylglycerol kinase modulates long-term thermotactic behavioral plasticity in C. elegans
David Biron, Mayumi Shibuya, Christopher Gabel, Sara M Wasserman, Damon A Clark, Adam Brown, Piali Sengupta & Aravinthan D T Samuel Nature Neuroscience9, 14991505
(December 2006); doi:10.1038/nn1796
| Summary | Full Text (HTML / PDF) |
article Dynorphin A activates bradykinin receptors to maintain neuropathic pain
Josephine Lai, Miaw-Chyi Luo, Qingmin Chen, Shouwu Ma, Luis R Gardell, Michael H Ossipov & Frank Porreca Nature Neuroscience9, 15341540
(December 2006); doi:10.1038/nn1804
| Summary | Full Text (HTML / PDF) |
article Epidermal RANKL controls regulatory T-cell numbers via activation of dendritic cells
Karin Loser, Annette Mehling, Stefanie Loeser, Jenny Apelt, Annegret Kuhn, Stephan Grabbe, Thomas Schwarz, Josef M Penninger & Stefan Beissert Nature Medicine12, 13721379
(December 2006); doi:10.1038/nm1518
| Summary | Full Text (HTML / PDF) |
news and views Skin controls immune regulators
Tomoyuki Yamaguchi & Shimon Sakaguchi Nature Medicine12, 13581359
(December 2006); doi:10.1038/nm1206-1358
| Summary | Full Text (HTML / PDF) |
letter Klotho converts canonical FGF receptor into a specific receptor for FGF23
Itaru Urakawa, Yuji Yamazaki, Takashi Shimada, Kousuke Iijima, Hisashi Hasegawa, Katsuya Okawa, Toshiro Fujita, Seiji Fukumoto and Takeyoshi Yamashita Nature444, 770774
(7 December 2006); doi:10.1038/nature05315
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article The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Sharon E Haynes, Gunther Hollopeter, Guang Yang, Dana Kurpius, Michael E Dailey, Wen-Biao Gan & David Julius Nature Neuroscience9, 15121519
(December 2006); doi:10.1038/nn1805
| Summary | Full Text (HTML / PDF) |
news and views Triggering the brain's pathology sensor
Helmut Kettenmann Nature Neuroscience9, 14631464
(December 2006); doi:10.1038/nn1206-1463
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article Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
Attila Mócsai, Clare L Abram, Zoltán Jakus, Yongmei Hu, Lewis L Lanier & Clifford A Lowell Nature Immunology7, 13261333
(December 2006); doi:10.1038/ni1407
| Summary | Full Text (HTML / PDF) |
news and views Integrins and ITAMs: more than just good neighbors
Mark L Kahn & Gary A Koretzky Nature Immunology7, 12861288
(December 2006); doi:10.1038/ni1206-1286
| Summary | Full Text (HTML / PDF) |
November
letter Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites
Alastair M. Hosie, Megan E. Wilkins, Helena M. A. da Silva and Trevor G. Smart Nature444, 486489
(23 November 2006); doi:10.1038/nature05324
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review Toll-like receptors in systemic autoimmune disease
Ann Marshak-Rothstein Nature Reviews Immunology6, 823835
(November 2006); doi:10.1038/nri1957
| Summary | Full Text (HTML / PDF) |
article IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
P Hande Özdinler & Jeffrey D Macklis Nature Neuroscience9, 13711381
(November 2006); doi:10.1038/nn1789
| Summary | Full Text (HTML / PDF) |
article RhoH GTPase recruits and activates Zap70 required for T cell receptor signaling and thymocyte development
Yi Gu, Hee-Don Chae, Jamie E Siefring, Aparna C Jasti, David A Hildeman & David A Williams Nature Immunology7, 11821190
(November 2006); doi:10.1038/ni1396
| Summary | Full Text (HTML / PDF) |
letter A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling
Adam Friedman and Norbert Perrimon Nature444, 230234
(09 November 2006); doi:10.1038/nature05280
| First Paragraph | Full Text (HTML / PDF) |
letter Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor
air Ben-Chaim1, Baron Chanda, Nathan Dasca, Francisco Bezanilla, Itzchak Parnas and Hanna Parnas1 Nature444, 106109
(02 November 2006); doi:10.1038/nature05259
| Summary | Full Text (HTML / PDF) |
review The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes
David J. Rawlings, Karen Sommer and Miguel E. Moreno-García Nature Reviews Immunology6, 799812
(November 2006); doi:10.1038/nri1944
| Summary | Full Text (HTML / PDF) |
October
review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology6, 728740
(October 2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
article Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
Sara K Custer, Gwenn A Garden, Nishi Gill, Udo Rueb, Randell T Libby, Christian Schultz, Stephan J Guyenet, Thomas Deller, Lesnick E Westrum, Bryce L Sopher & Albert R La Spada Nature Neuroscience9, 13021311
(September 2006); doi:10.1038/nn1750
| Summary | Full Text (HTML / PDF) |
news and views Intercellular miscommunication in polyglutamine pathogenesis
Christopher A Ross & Don W Cleveland Nature Neuroscience9, 12051206
(September 2006); doi:10.1038/nn1006-1205
| Summary | Full Text (HTML / PDF) |
perspective Channelrhodopsin-2 and optical control of excitable cells
Feng Zhang, Li-Ping Wang, Edward S Boyden & Karl Deisseroth Nature Methods5, 785792
(October 2006); doi:10.1038/nmeth936
| Summary | Full Text (HTML / PDF) |
article State-based discovery: a multidimensional screen for small-molecule modulators of EGF signaling
Mark Sevecka & Gavin MacBeath Nature Methods5, 825831
(October 2006); doi:10.1038/nmeth931
| Summary | Full Text (HTML / PDF) |
article Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1
Kyung-Chul Choi, Youn Sook Lee, Seunghwan Lim, Hyo Kyoung Choi, Chang-Hun Lee, Eun-Kyung Lee, Suntaek Hong, In-Hoo Kim, Seong-Jin Kim & Seok Hee Park Nature Immunology7, 10571065
(2006); doi:10.1038/ni1383
| Summary | Full Text (HTML / PDF) |
article Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding
Estuardo Robles & Timothy M Gomez Nature Neurology9, 12741283
(2006); doi:10.1038/nn1762
| Summary | Full Text (HTML / PDF) |
news and views Complementary therapies for inflammation
Yi Wang Nature Biotechnology24, 12241226
(2006); doi:10.1038/nbt1006-1224
| Summary | Full Text (HTML / PDF) |
news and views Signalling platforms that modulate the inflammatory response: new targets for drug development
Christopher. A. McCulloch, Gregory P. Downey and Hani El-Gabalawy Nature Reviews Drug Discovery5, 864876
(2006); doi:10.1038/nrd2109
| Summary | Full Text (HTML / PDF) |
letter Bidirectional control of CNS capillary diameter by pericytes
Claire M. Peppiatt, Clare Howarth, Peter Mobbs and David Attwell Nature443, 700704
(12 October 2006); doi:10.1038/nature05193
| Summary | Full Text (HTML / PDF) |
article The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
Michael Carty, Rory Goodbody, Martina Schröder, Julianne Stack, Paul N Moynagh & Andrew G Bowie Nature Immunology7, 10741081
(2006); doi:10.1038/ni1382
| Summary | Full Text (HTML / PDF) |
news and views DisSARMing Toll-like receptor signaling
Luke A J O'Neill Nature Immunology7, 10231025
(2006); doi:10.1038/ni1006-1023
| Summary | Full Text (HTML / PDF) |
review Receptor editing in lymphocyte development and central tolerance
David Nemazee Nature Reviews Immunology7, 728740
(2006); doi:10.1038/nri1939
| Summary | Full Text (HTML / PDF) |
article NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
Liming Pei, Hironori Waki, Bhavapriya Vaitheesvaran, Damien C Wilpitz, Irwin J Kurland & Peter Tontonoz Nature Medicine12, 10481055
(2006); doi:10.1038/nm1471
| Summary | Full Text (HTML / PDF) |
letter TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis
Carolyn G King, Takashi Kobayashi, Pedro J Cejas, Taesoo Kim, Kwiyeom Yoon, Gregory K Kim, Elise Chiffoleau, Somia P Hickman, Patrick T Walsh, Laurence A Turka & Yongwon Choi Nature Medicine12, 10881092
(2006); doi:10.1038/nm1449
| Summary | Full Text (HTML / PDF) |
review Mechanisms of cutaneous toxicities to EGFR inhibitors
Mario E. Lacouture Nature Reviews Cancer6, 803812
(October 2006); doi:10.1038/nrc1970
| Summary | Full Text (HTML / PDF) |
September
review IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
Kenya Honda and Tadatsugu Taniguchi Nature Reviews Immunology6, 644658
(September 2006); doi:10.1038/nri1900
| Summary | Full Text (HTML / PDF) |
letter Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning
John A. D'Orazio, Tetsuji Nobuhisa, Rutao Cui, Michelle Arya, Malinda Spry, Kazumasa Wakamatsu, Vivien Igras, Takahiro Kunisada, Scott R. Granter, Emi K. Nishimura, Shosuke Ito and David E. Fisher Nature443, 340344
(21 September 2006); doi:10.1038/nature05098
| Summary | Full Text (HTML / PDF) |
letter Structure of the insulin receptor ectodomain reveals a folded-over conformation
Neil M. McKern, Michael C. Lawrence, Victor A. Streltsov, Mei-Zhen Lou, Timothy E. Adams, George O. Lovrecz, Thomas C. Elleman, Kim M. Richards, John D. Bentley, Patricia A. Pilling, Peter A. Hoyne, Kellie A. Cartledge, Tam M. Pham, Jennifer L. Lewis, Sonia E. Sankovich, Violet Stoichevska, Elizabeth Da Silva, Christine P. Robinson, Maurice J. Frenkel, Lindsay G. Sparrow, Ross T. Fernley, V. Chandana Epa and Colin W. Ward Nature443, 218221
(14 September 2006); doi:10.1038/nature05106
| First Paragraph | Full Text (HTML / PDF) |
opinion Toll-like receptors as molecular switches
Nicholas J. Gay, Monique Gangloff and Alexander N. R. Weber Nature Reviews Immunology6, 693698
(September 2006); doi:10.1038/nri1916
| Summary | Full Text (HTML / PDF) |
article Cool-1 functions as an essential regulatory node for EGFreceptor- and Src-mediated cell growth
Qiyu Feng, Dan Baird, Xu Peng, Jianbin Wang, Thi Ly, Jun-Lin Guan & Richard A. Cerione Nature Cell Biology8, 945956
(September 2006); doi:10.1038/ncb1453
| Summary | Full Text (HTML / PDF) |
news and views Src transforms in a Cool way
Jeffrey R. Peterson & Jonathan Chernoff Nature Cell Biology8, 905907
(September 2006); doi:10.1038/ncb0906-905
| Summary | Full Text (HTML / PDF) |
August
letter NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus
Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage Nature442, 929933
(24 August 2006); doi:10.1038/nature05028
| First Paragraph | Full Text (HTML / PDF) |
article The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
Yisong Y Wan, Hongbo Chi, Min Xie, Michael D Schneider & Richard A Flavell Nature Immunology7, 851858
(August 2006); doi:10.1038/ni1355
| Summary | Full Text (HTML / PDF) |
letter ErbB2 receptor tyrosine kinase signaling mediates early demyelination induced by leprosy bacilli
Nikos Tapinos, Makoto Ohnishi & Anura Rambukkana Nature Medicine12, 961966
(August 2006); doi:10.1038/nm1433
| Summary | Full Text (HTML / PDF) |
article A second class of chemosensory receptors in the olfactory epithelium
Stephen D. Liberles and Linda B. Buck Nature442, 645650
(10 August 2006); doi:10.1038/nature05066
| Summary | Full Text (HTML / PDF) |
news and views Neuroscience: An extra dimension to olfaction
John Ngai Nature442, 637638
(10 August 2006); doi:10.1038/nature05001
| Full Text (HTML / PDF) |
letter Mesodermal Wnt2b signalling positively regulates liver specification
Elke A. Ober, Heather Verkade, Holly A. Field and Didier Y. R. Stainier Nature442, 688691
(10 August 2006); doi:10.1038/nature04888
| First Paragraph | Full Text (HTML / PDF) |
article The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl–Crk pathway
Nicole K. Noren, Gabriele Foos, Craig A. Hauser & Elena B. Pasquale Nature Cell Biology8, 815825
(10 August 2006); doi:10.1038/ncb1438
| First Paragraph | Full Text (HTML / PDF) |
news and views Eph tumour suppression: the dark side of Gleevec
Jean Y. J. Wang Nature Cell Biology8, 785786
(10 August 2006); doi:10.1038/ncb0806-785
| First Paragraph | Full Text (HTML / PDF) |
review P2X receptors as cell-surface ATP sensors in health and disease
Baljit S. Khakh and R. Alan North Nature442, 527532
(02 August 2006); doi:10.1038/nature04886
| First Paragraph | Full Text (HTML / PDF) |
July
article JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
Gerardo Morfini, Gustavo Pigino, Györgyi Szebenyi, Yimei You, Sarah Pollema & Scott T Brady Nature Neuroscience9, 907916
(June 2006); doi:10.1038/nn1717
| Summary | Full Text (HTML / PDF) |
article Interleukin 15-dependent crosstalk between conventional and plasmacytoid dendritic cells is essential for CpG-induced immune activation
Seiichi Kuwajima, Taku Sato, Kazuto Ishida, Hiroyuki Tada, Hiroyuki Tezuka & Toshiaki Ohteki Nature Immunology7, 740746
(July 2006); doi:10.1038/ni1348
| Summary | Full Text (HTML / PDF) |
news and views Division of labor and cooperation between dendritic cells
Bali Pulendran Nature Immunology7, 699700
(July 2006); doi:10.1038/ni0706-699
| Summary | Full Text (HTML / PDF) |
article VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis
Betty Y Y Tam, Kevin Wei, John S Rudge, Jana Hoffman, Joceyln Holash, Sang-ki Park, Jenny Yuan, Colleen Hefner, Cecile Chartier, Jeng-Shin Lee, Shelly Jiang, Nihar R Niyak, Frans A Kuypers, Lisa Ma, Uma Sundram, Grace Wu, Joseph A Garcia, Stanley L Schrier, Jacquelyn J Maher, Randall S Johnson, George D Yancopoulos, Richard C Mulligan & Calvin J Kuo Nature Medicine7, 793800
(July 2006); doi:10.1038/nm1428
| Summary | Full Text (HTML / PDF) |
news and views VEGF inhibitors make blood
Christian Fischer, Peter Carmeliet & Edward M Conway Nature Medicine7, 732734
(July 2006); doi:10.1038/nm0706-732
| Summary | Full Text (HTML / PDF) |
letter Altered neuregulin 1-erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia
Chang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E Gur, Wade H Berrettini, Kalindi Bakshi, Joshua Kamins, Karin E Borgmann-Winter, Steven J Siegel, Robert J Gallop & Steven E Arnold Nature Medicine442, 824828
(July 2006); doi:10.1038/nm1418
| Summary | Full Text (HTML / PDF) |
news and views Schizophrenia: signals from the other side
Gerald D Fischbach Nature Medicine7, 7341735
(July 2006); doi:10.1038/nm0706-734
| Summary | Full Text (HTML / PDF) |
review EGF-ERBB signalling: towards the systems level
Ami Citri and Yosef Yarden Nature Reviews Molecular Cell Biology7, 505516
(July 2006); doi:10.1038/nrm1962
| Summary | Full Text (HTML / PDF) |
article Fas ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity
Veronika Groh, Kimberly Smythe, Zhenpeng Dai & Thomas Spies Nature Immunology7, 755762
(28 May 2006); doi:10.1038/ni1350
| First Paragraph | Full Text (HTML / PDF) |
article The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome
Mohammed Sebaihia, Brendan W Wren, Peter Mullany, Neil F Fairweather, Nigel Minton, Richard Stabler, Nicholas R Thomson, Adam P Roberts, Ana M Cerdeño-Tárraga, Hongmei Wang, Matthew TG Holden, Anne Wright, Carol Churcher, Michael A Quail, Stephen Baker, Nathalie Bason, Karen Brooks, Tracey Chillingworth, Ann Cronin, Paul Davis, Linda Dowd, Audrey Fraser, Theresa Feltwell, Zahra Hance, Simon Holroyd, Kay Jagels, Sharon Moule, Karen Mungall, Claire Price, Ester Rabbinowitsch, Sarah Sharp, Mark Simmonds, Kim Stevens, Louise Unwin, Sally Whithead, Bruno Dupuy, Gordon Dougan, Bart Barrell & Julian Parkhill Nature Genetics38, 779786
(25 June 2006); doi:10.1038/ng1830
| First Paragraph | Full Text (HTML / PDF) |
review Intracellular pattern recognition receptors in the host response
Etienne Meylan, Jürg Tschopp and Michael Karin Nature442, 3944
(06 July 2006); doi:10.1038/nature04946
| Summary | Full Text (HTML / PDF) |
article AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
Vikram R Rao, Sean A Pintchovski, Jeannie Chin, Carol L Peebles, Siddhartha Mitra & Steven Finkbeiner Nature Neuroscience7, 887895
(July 2006); doi:10.1038/nn1708
| Summary | Full Text (HTML / PDF) |
June
review article Therapeutic potential of Toll-like receptor 9 activation
Arthur M. Krieg Nature Reviews Drug Discovery5, 471484
(June 2006); doi:10.1038/nrd2059
| Summary | Full Text (HTML / PDF) |
letter Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis
Noriko Takegahara, Hyota Takamatsu, Toshihiko Toyofuku, Tohru Tsujimura, Tatsusada Okuno, Kazunori Yukawa, Masayuki Mizui, Midori Yamamoto, Durbaka V.R. Prasad, Kazuhiro Suzuki, Masaru Ishii, Kenta Terai, Masayuki Moriya, Yuji Nakatsuji, Saburo Sakoda, Shintaro Sato, Shizuo Akira, Kiyoshi Takeda, Masanori Inui, Toshiyuki Takai, Masahito Ikawa, Masaru Okabe, Atsushi Kumanogoh & Hitoshi Kikutani Nature Cell Biology8, 615 - 622
(June 2006); doi:10.1038/ncb1416
| Summary | Full Text (HTML / PDF) |
news and views Semaphorin pathways orchestrate osteogenesis
Luca Tamagnone & Silvia Giordano Nature Cell Biology8, 545 - 547
(June 2006); doi:10.1038/ncb0606-545
| Summary | Full Text (HTML / PDF) |
news and views TGF-ß, a 'double agent' in the immune pathology war
Daniel J Cua & Robert A Kastelein Nature Immunology7, 557 - 559
(June 2006); doi:10.1038/ni0606-557
| Summary | Full Text (HTML / PDF) |
letter Social interactions among epithelial cells during tracheal branching morphogenesis
Amin S. Ghabrial and Mark A. Krasnow Nature441, 746749
(08 June 2006); doi:10.1038/nature04829
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review article The SIRP family of receptors and immune regulation
A. Neil Barclay and Marion H. Brown
(June 2006); doi:10.1038/nri1859
| Summary | Full Text (HTML / PDF) |
news and views Predictable trends in protein noise
Craig R Roy and Dario S Zamboni Nature Genetics38, 610611
(June 2006); doi:10.1038/ng0606-610
| First Paragraph | Full Text (HTML / PDF) |
article Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O
Takafumi Shintani, Masaru Ihara, Hiraki Sakuta, Hiroo Takahashi, Ikuko Watakabe and Masaharu Noda Nature Neuroscience9, 761769
(08 June 2006); doi:10.1038/nn1697
| First Paragraph | Full Text (HTML / PDF) |
May
letter Syndecan-4 regulates non-canonical Wnt signalling and is essential for convergent and extension movements in Xenopus embryos
Rosana Muñoz, Mauricio Moreno, Carlos Oliva, Claudio Orbenes & Juan Larraín Nature Cell Biology8, 492500
(May 2006); doi:10.1038/ncb1399
| Summary | Full Text (HTML / PDF) |
article The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt–ß–catenin signalling through Dishevelled
Yosuke Funato, Tatsuo Michiue, Makoto Asashima & Hiroaki Miki Nature Cell Biology8, 501508
(May 2006); doi:10.1038/ncb1405
| Summary | Full Text (HTML / PDF) |
article Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1
Roi Gazit, Raizy Gruda, Moran Elboim, Tal I Arnon, Gil Katz, Hagit Achdout, Jacob Hanna, Udi Qimron, Guy Landau, Evgenia Greenbaum, Zichria Zakay-Rones, Angel Porgador & Ofer Mandelboim Nature Immunology7, 517523
(May 2006); doi:10.1038/ni1322
| Summary | Full Text (HTML / PDF) |
news and views Natural cytotoxicity receptors: influenza virus in the spotlight
Thomas Spies & Veronika Groh Nature Immunology7, 443444
(May 2006); doi:10.1038/ni0506-443
| Summary | Full Text (HTML / PDF) |
article Metabolic biotinylation of cell surface receptors for in vivo imaging
Bakhos A Tannous, Jan Grimm, Katherine F Perry, John W Chen, Ralph Weissleder & Xandra O Breakefield Nature Methods3, 391396
(May 2006); doi:10.1038/nmeth875
| Summary | Full Text (HTML / PDF) |
article Endocytosis and synaptic removal of NR3A–containing NMDA receptors by PACSIN1/syndapin1
Isabel Pérez–Otaño, Rafael Luján, Steven J Tavalin, Markus Plomann, Jan Modregger, Xiao–Bo Liu, Edward G Jones, Stephen F Heinemann, Donald C Lo, Michael D Ehlers Nature Neuroscience9, 611621
(May 2006); doi:10.1038/nn1680
| Summary | Full Text (HTML / PDF) |
article Clearing obsolete NMDA receptors
Annette Markus Nature Neuroscience9, 598
(May 2006); doi:10.1038/nn0506-598
| Summary | Full Text (HTML / PDF) |
review Exploiting pathogenic Escherichia coli to model transmembrane receptor signalling
Richard D. Hayward, John M. Leong, Vassilis Koronakis, Kenneth G. Campellone Nature Reviews Microbiology4, 429435
(May 2006); doi:10.1038/nrmicro1391
| Summary | Full Text (HTML / PDF) |
article NKG2D–mediated signaling requires a DAP10–bound Grb2–Vav1 intermediate and phosphatidylinositol–3–kinase in human natural killer cells
Jadee L Upshaw, Laura N Arneson, Renee A Schoon, Christopher J Dick, Daniel D Billadeau & Paul J Leibson Nature Immunology7, 524532
(May 2006); doi:10.1038/ni1325
| Summary | Full Text (HTML / PDF) |
article Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane
Guillermo A Yudowski, Manojkumar A Puthenveedu & Mark von Zastrow Nature Neuroscience9, 622627
(May 2006); doi:10.1038/nn1679
| Summary | Full Text (HTML / PDF) |
letter Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation
Ingvar Ferby, Markus Reschke, Oliver Kudlacek, Pjotr Knyazev, Guido Pantè, Kerstin Amann, Wolfgang Sommergruber, Norbert Kraut, Axel Ullrich, Reinhard Fässler & Rüdiger Klein Nature Medicine12, 568573
(May 2006) | doi:10.1038/nm1401
| First Paragraph | Full Text (HTML / PDF) |
review article Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia
Clemens Grabher, Harald von Boehmer and A. Thomas Look Nature Reviews Cancer6, 347359
(May 2006); doi:10.1038/nrc1880
| Summary | Full Text (HTML / PDF) |
article Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Jodie L Babitt, Franklin W Huang, Diedra M Wrighting, Yin Xia, Yisrael Sidis, Tarek A Samad, Jason A Campagna, Raymond T Chung, Alan L Schneyer, Clifford J Woolf, Nancy C Andrews & Herbert Y Lin Nature Genetics38, 531539
(May 2006) | doi:10.1038/ng1777
| First Paragraph | Full Text (HTML / PDF) |
news and views Iron metabolism meets signal transduction
Gregory J Anderson & David M Frazer Nature Genetics38, 503503
(May 2006) | doi:10.1038/ng0506-503
| First Paragraph | Full Text (HTML / PDF) |
brief communication Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
Karen Plant, Kenneth A Pelkey, Zuner A Bortolotto, Daiju Morita, Akira Terashima, Chris J McBain, Graham L Collingridge & John T R Isaac Nature Neuroscience9, 602604
(May 2006) | doi:10.1038/nn1678
| First Paragraph | Full Text (HTML / PDF) |
news and views LTP: AMPA receptors trading places
Julie A Kauer & Robert C Malenka Nature Neuroscience9, 593594
(May 2006) | doi:10.1038/nn0506-593
| First Paragraph | Full Text (HTML / PDF) |
April
letter Synaptic scaling mediated by glial TNF-α
David Stellwagen and Robert C. Malenka Nature440, 10541059
(20 April 2006); doi:10.1038/nature04671
| First Paragraph | Full Text (HTML / PDF) |
article Early hematopoietic lineage restrictions directed by Ikaros
Toshimi Yoshida, Samuel Yao-Ming Ng, Juan Carlos Zuniga-Pflucker & Katia Georgopoulos Nature Immunology7, 382391
(April 2006); doi:10.1038/ni1314
| First Paragraph | Full Text (HTML / PDF) |
news and views Hematopoiesis flies high with Ikaros
Stephen T Smale & Kenneth Dorshkind Nature Immunology7, 367369
(April 2006); doi:10.1038/ni0406-367
| First Paragraph | Full Text (HTML / PDF) |
article UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
Carolyn E Adler, Richard D Fetter & Cornelia I Bargmann Nature Neuroscience9, 511 - 518
(April 2006); doi:10.1038/nn1666
| Summary | Full Text (HTML / PDF) |
letter IkB kinase-a is critical for interferon-α production induced by Toll-like receptors 7 and 9
Katsuaki Hoshino, Takahiro Sugiyama, Mitsuru Matsumoto, Takashi Tanaka, Masuyoshi Saito, Hiroaki Hemmi, Osamu Ohara, Shizuo Akira and Tsuneyasu Kaisho Nature440, 949953
(13 April 2006); doi:10.1038/nature04641
| First Paragraph | Full Text (HTML / PDF) |
review article ITAM-mediated tonic signalling through pre-BCR and BCR complexes
John G. Monroe Nature Reviews Immunology4, 265275
(April 2006); doi:10.1038/nri1808
| Summary | Full Text (HTML / PDF) |
March
letter A C. elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue
Wei Li, Zhaoyang Feng, Paul W. Sternberg and X. Z. Shawn Xu Nature440, 684687
(30 March 2006); doi:10.1038/nature04538
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review article CATERPILLERs, pyrin and hereditary immunological disorders
Jenny P.-Y. Ting, Daniel L. Kastner and Hal M. Hoffman Nature Reviews Immunology6, 183195
(March 2006); doi:10.1038/nri1788
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letter Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent
Fabiana S Machado, James E Johndrow, Lisia Esper, Alexandra Dias, Andre Bafica, Charles N Serhan & Julio Aliberti Nature Medicine12, 330334
(March 2006); doi:10.1038/nm1355
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article Silencing of EphA3 through a cis interaction with ephrinA5
Ricardo F Carvalho, Martin Beutler, Katharine J M Marler, Bernd Knöll, Elena Becker-Barroso, R Heintzmann, Tony Ng & Uwe Drescher Nature Neuroscience9, 322330
(March 2006); doi:10.1038/nn1655
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article Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
Natalya V Serbina and Eric G Pamer Nature Immunology7, 311317
(March 2006); doi:10.1038/ni1309
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review article Adenosine receptors as therapeutic targets
Kenneth A. Jacobson and Zhan-Guo Gao Nature Reviews Drug Discovery5, 247264
(March 2006); doi:10.1038/nrd1983
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research article Neurotrophins mediate human embryonic stem cell survival
April D Pyle, Leslie F Lock and Peter J Donovan Nature Biotechnology24, 344350
(March 2006); doi:10.1038/nbt1189
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research article CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells
Daniella Herszfeld, Ernst Wolvetang, Emma Langton-Bunker, Tung-Liang Chung, Adam A Filipczyk, Souheir Houssami, Pegah Jamshidi, Karen Koh, Andrew L Laslett, Anna Michalska, Linh Nguyen, Benjamin E Reubinoff, Irene Tellis, Jonathan M Auerbach, Carol J Ording, Leendert H J Looijenga and Martin F Pera Nature Biotechnology24, 351357
(March 2006); doi:10.1038/nbt1197
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review article cFLIP regulation of lymphocyte activation and development
Ralph C. Budd, Wen-Chen Yeh and Jürg Tschopp Nature Reviews Immunology6, 196204
(March 2006); doi:10.1038/nri1787
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review article Integrated signalling pathways for mast-cell activation
Alasdair M. Gilfillan and Christine Tkaczyk Nature Reviews Immunology6, 218230
(March 2006); doi:10.1038/nri1782
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letter Development of the signal in sensory rhodopsin and its transfer to the cognate transducer
Rouslan Moukhametzianov , Johann P. Klare, Rouslan Efremov, Christian Baeken, Annika Göppner, Jörg Labahn, Martin Engelhard, Georg Büldt and Valentin I. Gordeliy Nature440, 115119
(02 March 2006); doi:10.1038/nature04520
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February
letter NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
I. Micu, Q. Jiang, E. Coderre, A. Ridsdale, L. Zhang, J. Woulfe, X. Yin, B. D. Trapp, J. E. McRory, R. Rehak, G. W. Zamponi, W. Wang and P. K. Stys Nature439, 988992
(23 February 2006); doi:10.1038/nature04474
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article Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
Yaya Wang, Yawei Tang, Lin Teng, Yalan Wu, Xiaohui Zhao and Gang Pei Nature Immunology7, 139147
(February 2006); doi:10.1038/ni1294
| Abstract | Full Text (HTML/PDF) |
article Ablation of CD22 in ligand-deficient mice restores B cell receptor signaling
Brian E Collins, Brian A Smith, Per Bengtson and James C Paulson Nature Immunology7, 199206
(February 2006); doi:10.1038/ni1283
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letter Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity
Takayuki Kawano, Josef Anrather, Ping Zhou, Laibaik Park, Gang Wang, Kelly A Frys, Alexander Kunz, Sunghee Cho, Marcello Orio and Costantino Iadecola Nature Medicine12, 225229
(February 2006); doi:10.1038/nm1362
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article Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord
Liang-Fong Wong, Ping K Yip, Anna Battaglia, John Grist, Jonathan Corcoran, Malcolm Maden, Mimoun Azzouz, Susan M Kingsman, Alan J Kingsman, Nicholas D Mazarakis and Stephen B McMahon Nature Neuroscience9, 243250
(February 2006); doi:10.1038/nn1622
| Abstract | Full Text (HTML/PDF) |
review article Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
Stuart A. Lipton Nature Reviews Drug Discovery5, 160170
(February 2006); doi:10.1038/nrd1958
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article Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle
Marçal Vilar, Maribel Murillo-Carretero, Helena Mira, Kalle Magnusson, Valerie Besset and Carlos F Ibáñez The EMBO Journal advance online publication;
(23 February 2006); doi:10.10.1038/sj.emboj.7601017
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letter The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1
Karuppiah Muthumani, Andrew Y. Choo, Wei-Xing Zong, Muniswamy Madesh, Daniel S. Hwang, Arumugam Premkumar, Khanh P. Thieu, Joann Emmanuel, Sanjeev Kumar, Craig B. Thompson and David B. Weiner Nature Cell Biology8, 170179
(February 2006); doi:10.1038/ncb1352
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article Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity
Nicholas S Wilson, Georg M N Behrens, Rachel J Lundie, Christopher M Smith, Jason Waithman, Louise Young, Simon P Forehan, Adele Mount, Raymond J Steptoe, Ken D Shortman, Tania F de Koning-Ward, Gabrielle T Belz, Francis R Carbone, Brendan S Crabb, William R Heath and Jose A Villadangos Nature Immunology7, 165172
(February 2006); doi:10.1038/ni1300
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letter GABA regulates synaptic integration of newly generated neurons in the adult brain
Shaoyu Ge, Eyleen L. K. Goh, Kurt A. Sailor, Yasuji Kitabatake, Guo-li Ming and Hongjun Song Nature439, 589593
(02 February 2006); doi:10.1038/nature04404
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letter Regulation of ubiquitin-binding proteins by monoubiquitination
Daniela Hoeller, Nicola Crosetto, Blagoy Blagoev, Camilla Raiborg, Ritva Tikkanen, Sebastian Wagner, Katarzyna Kowanetz, Rainer Breitling, Matthias Mann, Harald Stenmark and Ivan Dikic Nature Cell Biology8, 163169
(February 2006); doi:10.1038/ncb1354
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article Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
Ashley Mansell, Rosealee Smith, Sarah L Doyle, Pearl Gray, Jennifer E Fenner, Peter J Crack, Sandra E Nicholson, Douglas J Hilton, Luke A J O'Neill and Paul J Hertzog Nature Immunology7, 148155
(February 2006); doi:10.1038/ni1299
| Abstract | Full Text (HTML/PDF) |
news and views Mal-function of TLRs by SOCS
Takashi Kobayashi, Giichi Takaesu and Akihiko Yoshimura Nature Immunology7, 123124
(February 2006); doi:10.1038/ni0206-123
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January
news and views Kinase cogs go forward and reverse in the Wnt signaling machine
Trevor Dale Nature Structural and Molecular Biology13, 911
(January 2006); doi:10.1038/nsmb0106-9
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article The RNA-binding protein FCA is an abscisic acid receptor
Fawzi A. Razem, Ashraf El-Kereamy, Suzanne R. Abrams and Robert D. Hill Nature439, 290294
(19 January 2006); doi:10.1038/nature04373
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review article SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond
Gary A. Koretzky, Farhad Abtahian and Michael A. Silverman Nature Reviews Immunology6, 6778
(January 2006); doi:10.1038/nri1750
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letter Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
Hans Häcker, Vanessa Redecke, Blagoy Blagoev, Irina Kratchmarova, Li-Chung Hsu, Gang G. Wang, Mark P. Kamps, Eyal Raz, Hermann Wagner, Georg Häcker, Matthias Mann and Michael Karin Nature439, 204207
(12 January 2006); doi:10.1038/nature04369
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letter Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
Gagik Oganesyan, Supriya K. Saha, Beichu Guo, Jeannie Q. He, Arash Shahangian, Brian Zarnegar, Andrea Perry and Genhong Cheng Nature439, 208211
(12 January 2006); doi:10.1038/nature04374
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review article Dectin-1: a signalling non-TLR pattern-recognition receptor
Gordon D. Brown Nature Reviews Immunology6, 3343
(January 2006); doi:10.1038/nri1745
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article IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis
Stefan Fichtner-Feigl, Warren Strober, Koji Kawakami, Raj K Puri and Atsushi Kitani Nature Medicine12, 99106
(January 2006); doi:10.1038/nm1332
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article Mechanistic basis of pre-T cell receptor–mediated autonomous signaling critical for thymocyte development
Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Koji Ogata, Kumiko Sakata-Sogawa, Michio Hiroshima, David L Wiest, Makio Tokunaga and Takashi Saito Nature Immunology7, 6775
(January 2006); doi:10.1038/ni1290
| Abstract | Full Text (HTML/PDF) |
review article Immune regulation by SLAM family receptors and SAP-related adaptors
André Veillette Nature Reviews Immunology6, 5666
(January 2006); doi:10.1038/nri1761
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article ORL1 receptor-mediated internalization of N-type calcium channels
Christophe Altier, Houman Khosravani, Rhian M Evans, Shahid Hameed, Jean B Peloquin, Brian A Vartian, Lina Chen, Aaron M Beedle, Stephen S G Ferguson, Alexandre Mezghrani, Stefan J Dubel, Emmanuel Bourinet, John E McRory and Gerald W Zamponi Nature Neuroscience9, 3140
(January 2006); doi:10.1038/nn1605
| Abstract | Full Text (HTML/PDF) |
news and views Internalizing channels: a mechanism to control pain?
Diane Lipscombe and Jesica Raingo Nature Neuroscience9, 810
(January 2006); doi:10.1038/nn0106-8
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