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Research library: Microbiology

2003: December | November | October | September | August | July | June | May | April | March | February | January

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letters to nature
The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes
Lakshmanan Ganesh, Ezra Burstein, Anuradha Guha-Niyogi, Mark K. Louder, John R. Mascola, Leo W. J. Klomp, Cisca Wijmenga, Colin S. Duckett and Gary J. Nabel
Nature 426, 853–857
(18 December 2003); doi:10.1038/nature02171
| First Paragraph | Full Text (HTML / PDF) |

letter
Pyruvate kinase deficiency in mice protects against malaria
Gundula Min-Oo, Anny Fortin, Mi-Fong Tam, André Nantel, Mary M Stevenson and Philippe Gros
Nature Genetics 35, 357–362
(December 2003); doi:10.1038/ng1260
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article
Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility
Kelly D Smith, Erica Andersen-Nissen, Fumitaka Hayashi, Katie Strobe, Molly A Bergman, Sara L Rassoulian Barrett, Brad T Cookson and Alan Aderem
Nature Immunology 4, 1247–1253
(December 2003); doi:10.1038/ni1011
| Abstract | Full Text (HTML/PDF) |

news and views
TLR5 takes aim at bacterial propeller
Jean-Marc Reichhart
Nature Immunology 4, 1159–1160
(December 2003); doi:10.1038/ni1203-1159
| Full Text (HTML/PDF) |

letters to nature
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
Wenhui Li, Michael J. Moore, Natalya Vasilieva, Jianhua Sui, Swee Kee Wong, Michael A. Berne, Mohan Somasundaran, John L. Sullivan, Katherine Luzuriaga, Thomas C. Greenough, Hyeryun Choe & Michael Farzan
Nature 426, 450–454
(27 November 2003); doi:10.1038/nature02145
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article
HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation
Mariana Marin, Kristine M. Rose, Susan L. Kozak and David Kabat
Nature Medicine 9, 1398–1403
(November 2003); doi:10.1038/nm946
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letter
The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif
Ann M. Sheehy, Nathan C. Gaddis and Michael H. Malim
Nature Medicine 9, 1404–1407
(November 2003); doi:10.1038/nm945
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news and views
Microbiology: Destructive approach
Amanda Tromans
Nature 426, 23
(06 November 2003); doi:10.1038/426023a
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article
Hepatocyte growth factor and its receptor are required for malaria infection
Margarida Carrolo, Silvia Giordano, Laura Cabrita-Santos, Simona Corso, Ana M Vigário, Susana Silva, Patricia Leirião, Daniel Carapau, Rosario Armas-Portela, Paolo M Comoglio, Ana Rodriguez and Maria M Mota
Nature Medicine 9, 1363–1369
(November 2003); doi:10.1038/nm947
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article
Structural determinants of SecB recognition by SecA in bacterial protein translocation
Jiahai Zhou and Zhaohui Xu
Nature Structural Biology 10, 942–947
(November 2003); doi:10.1038/nsb980
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article
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni
Sergio Verjovski-Almeida, Ricardo DeMarco, Elizabeth A L Martins, Pedro E M Guimarães, Elida P B Ojopi, Apuã C M Paquola, João P Piazza, Milton Y Nishiyama, Jr. João P Kitajima, Rachel E Adamson, Peter D Ashton, Maria F Bonaldo, Patricia S Coulson, Gary P Dillon, Leonardo P Farias, Sheila P Gregorio, Paulo L Ho, Ricardo A Leite, L Cosme C Malaquias, Regina C P Marques, Patricia A Miyasato, Ana L T O Nascimento, Fernanda P Ohlweiler, Eduardo M Reis, Marcela A Ribeiro, Renata G Sá, Gaëlle C Stukart, M Bento Soares, Cybele Gargioni, Toshie Kawano, Vanderlei Rodrigues, Alda M B N Madeira, R Alan Wilson, Carlos F M Menck, João C Setubal, Luciana C C Leite and Emmanuel Dias-Neto
Nature Genetics 35, 148–157
(October 2003); doi:10.1038/ng1237
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article
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
Agnes Le Bon, Nathalie Etchart, Cornelia Rossmann, Miranda Ashton, Sam Hou, Dirk Gewert, Persephone Borrow and David F Tough
Nature Immunology 4, 1009–1015
(October 2003); doi:10.1038/ni978
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news and views
Type I interferons promote cross-priming: more functions for old cytokines
Anne-Sophie Beignon, Mojca Skoberne and Nina Bhardwaj
Nature Immunology 4, 939–941
(October 2003); doi:10.1038/ni1003-939
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news and views
HIV's great escape
Mark Marsh and Markus Thali
Nature Medicine 9, 1262–1263
(October 2003); doi:10.1038/nm1003-1262
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article
HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration
Kunyan Zhang, G. Angus McQuibban, Claudia Silva, Georgina S. Butler, James B. Johnston, Janet Holden, Ian Clark-Lewis, Christopher M. Overall and Christopher Power
Nature Neuroscience 6, 1064–1071
(October 2003); doi:10.1038/nn1127
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news and views
Snip-snip, kill-kill: truncated SDF-1 and HIV-associated neurodegeneration
Richard M. Ransohoff
Nature Neuroscience 6, 1009–1011
(October 2003); doi:10.1038/nn1003-1009
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news and views
The ins and outs of cross-presentation
Kenneth L. Rock
Nature Immunology 4, 941–943
(October 2003); doi:10.1038/ni1003-941
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letters to nature
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
Pierre Guermonprez, Loredana Saveanu, Monique Kleijmeer, Jean Davoust, Peter van Endert and Sebastian Amigorena
Nature 425, 397–402
(25 September 2003); doi:10.1038/nature01911
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letters to nature
Phagosomes are competent organelles for antigen cross-presentation
Mathieu Houde, Sylvie Bertholet, Etienne Gagnon, Sylvain Brunet, Guillaume Goyette, Annie Laplante, Michael F. Princiotta, Pierre Thibault, David Sacks and Michel Desjardins
Nature 425, 402–406
(25 September 2003); doi:10.1038/nature01912
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news and views
Immunology: Professional secrets
Craig R. Roy
Nature 425, 351–352
(25 September 2003); doi:10.1038/425351a
| Full Text (HTML / PDF) |

article
Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria
Elsa Anes, Mark Philipp Kühnel, Evelyne Bos, Jose Moniz-Pereira, Anja Habermann and Gareth Griffiths
Nature Cell Biology 5, 793–802
(September 2003); doi:10.1038/ncb1036
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news and views
Phagosomes, fatty acids and tuberculosis
David G. Russell
Nature Cell Biology 5, 776–778
(September 2003); doi:10.1038/ncb0903-776
| Full Text (HTML/PDF) |

article
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
David Wald, Jinzhong Qin, Zhendong Zhao, Youcun Qian, Mayumi Naramura, Liping Tian, Jennifer Towne, John E. Sims, George R. Stark and Xiaoxia Li
Nature Immunology 4, 920–927
(September 2003); doi:10.1038/ni968
| Abstract | Full Text (HTML/PDF) |

news and views
SIGIRR puts the brakes on Toll-like receptors
Luke A. J. O'Neill
Nature Immunology 4, 823–824
(September 2003); doi:10.1038/ni0903-823
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article
Defective development and function of Bcl10-deficient follicular, marginal zone and B1 B cells
Liquan Xue, Stephan W Morris, Carlos Orihuela, Elaine Tuomanen, Xiaoli Cui, Renren Wen and Demin Wang
Nature Immunology 4, 857–865
(September 2003); doi:10.1038/ni963
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news and views
Escherichia coli gets the message
Klaus Winzer and Paul Williams
Nature Medicine 9, 1118–1119
(September 2003); doi:10.1038/nm0903-1118
| Full Text (HTML/PDF) |

article
Cyclophilin A modulates the sensitivity of HIV-1 to host restriction factors
Greg J. Towers, Theodora Hatziioannou, Simone Cowan, Stephen P. Goff, Jeremy Luban and Paul D. Bieniasz
Nature Medicine 9, 1138–1143
(September 2003); doi:10.1038/nm910
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news and views
HIV-1 infection: fooling the gatekeeper
Bryan R. Cullen
Nature Medicine 9, 1112–1113
(September 2003); doi:10.1038/nm0903-1112
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review article
DC-SIGN: escape mechanism for pathogens
Yvette van Kooyk and Teunis B. H. Geijtenbeek
Nature Reviews Immunology 3, 697–709
(September 2003); doi:10.1038/nri1182
| Abstract | Full Text (HTML / PDF) |

review article
A tale of two polymers: new insights into helical filaments
Edward H. Egelman
Nature Reviews Molecular Cell Biology 4, 621–631
(August 2003); doi:10.1038/nrm1176
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news and views
Anthrax delivers a lethal blow to host immunity
Michael N. Starnbach and R. John Collier
Nature Medicine 9, 996–997
(August 2003); doi:10.1038/nm0803-996
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article
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
K. Hoebe, X. Du, P. Georgel, E. Janssen, K. Tabeta, S. O. Kim, J. Goode, P. Lin, N. Mann, S. Mudd, K. Crozat, S. Sovath, J. Han and B. Beutler
Nature 424, 743–748
(14 August 2003); doi:10.1038/nature01889
| Abstract | Full Text (HTML / PDF) |

news and views
Immunology: Another toll road
Wen-Chen Yeh and Nien-Jung Chen
Nature 424, 736–737
(14 August 2003); doi:10.1038/424736a
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letter
Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells
Guy Tran Van Nhieu, Caroline Clair, Roberto Bruzzone, Marc Mesnil, Philippe Sansonetti and Laurent Combettes
Nature Cell Biology 5, 720–726
(August 2003); doi:10.1038/ncb1021
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review article
Class II cytokine receptors and their ligands: Key antiviral and inflammatory modulators
Jean-Christophe Renauld
Nature Reviews Immunology 3, 667–676
(August 2003); doi:10.1038/nri1153
| Summary | Full Text (HTML / PDF) |

news and views
Nefarious abuse
Melissa Pope
Nature Immunology 4, 729–730
(August 2003); doi:10.1038/ni0803-729
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letters to nature
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus
Xin Wang, Shu-Mei Huong, Marie L. Chiu, Nancy Raab-Traub and Eng-Shang Huang
Nature 424, 456–461
(24 July 2003); doi:10.1038/nature01818
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review article
Pathogens: raft hijackers
Santos Mañes, Gustavo del Real and Carlos Martínez-A
Nature Reviews Immunology 3, 557–568
(July 2003); doi:10.1038/nri1129
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review article
HIV-1 pathogenesis
Mario Stevenson
Nature Medicine 9, 853–860
(July 2003); doi:10.1038/nm0703-853
| Abstract | Full Text (HTML/PDF) |

perspectives
Timeline: The bicyclam AMD3100 story
Erik De Clercq
Nature Reviews Drug Discovery 2, 581–587
(July 2003); doi:10.1038/nrd1134
| Abstract | Full Text (HTML / PDF) |

letters to nature
Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin
Anshu Agrawal, Jai Lingappa, Stephen H. Leppla, Sudhanshu Agrawal, Abdul Jabbar, Conrad Quinn and Bali Pulendran
Nature 424, 329–334
(17 July 2003); doi:10.1038/nature01794
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article
The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens
Jens Lohr, Birgit Knoechel, Shuwei Jiang, Arlene H Sharpe and Abul K Abbas
Nature Immunology 4, 664–669
(July 2003); doi:10.1038/ni939
| Abstract | Full Text (HTML/PDF) |

letters to nature
HIV-1 Nef intersects the macrophage CD40L signalling pathway to promote resting-cell infection
Simon Swingler, Beda Brichacek, Jean-Marc Jacque, Catherine Ulich, Jin Zhou and Mario Stevenson
Nature 424, 213–219
(10 July 2003); doi:10.1038/nature01749
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news and views
HIV: Cross-talk and viral reservoirs
Roger J. Pomerantz
Nature 424, 136–137
(10 July 2003); doi:10.1038/424136a
| Full Text (HTML / PDF) |

article
Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea
Christine A Kirvan, Susan E Swedo, Janet S Heuser and Madeleine W Cunningham
Nature Medicine 9, 914–920
(July 2003); doi:10.1038/nm892
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news and views
Letting antibodies get to your head
Robert S Fujinami and Thayne L Sweeten
Nature Medicine 9, 823–825
(July 2003); doi:10.1038/nm0703-823
| Full Text (HTML/PDF) |

article
Subversion of the innate immune system by a retrovirus
Brooke A Jude, Yelena Pobezinskaya, Jennifer Bishop, Susannah Parke, Ruslan M Medzhitov, Alexander V Chervonsky and Tatyana V Golovkina
Nature Immunology 4, 573–578
(June 2003); doi:10.1038/ni926
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article
Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Dawei Li, Rui Zhao, Wayne Lilyestrom, Dahai Gai, Rongguang Zhang, James A. DeCaprio, Ellen Fanning, Andrzej Jochimiak, Gerda Szakonyi and Xiaojiang S. Chen
Nature 423, 512–518
(29 May 2003); doi:10.1038/nature01691
| Summary | Full Text (HTML / PDF) |

article
Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells
Julio Aliberti, Jesus G. Valenzuela, Vern B. Carruthers, Sara Hieny, John Andersen, Hugues Charest, Caetano Reis e Sousa, Alan Fairlamb, Jose M. Ribeiro and Alan Sher
Nature Immunology 4, 485–490
(May 2003); doi:10.1038/ni915
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article
The Drosophila immune system detects bacteria through specific peptidoglycan recognition
François Leulier, Claudine Parquet, Sebastien Pili-Floury, Ji-Hwan Ryu, Martine Caroff, Won-Jae Lee, Dominique Mengin-Lecreulx and Bruno Lemaitre
Nature Immunology 4, 478–484
(May 2003); doi:10.1038/ni922
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review article
Apoptosis as an HIV strategy to escape immune attack
Marie-Lise Gougeon
Nature Reviews Immunology 3, 392–404
(May 2003); doi:10.1038/nri1087
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review article
Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens
Carrie M. Rosenberger and B. Brett Finlay
Nature Reviews Molecular Cell Biology 4, 385–396
(May 2003); doi:10.1038/nrm1104
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article
Monoallelic expression of the murine gene encoding Toll-like receptor 4
João Pedro Pereira, Robert Girard, Richard Chaby, Ana Cumano and Paulo Vieira
Nature Immunology 4, 464–470
(May 2003); doi:10.1038/ni917
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article
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
Marina Karaghiosoff, Ralf Steinborn, Pavel Kovarik, Gernot Kriegshäuser, Manuela Baccarini, Birgit Donabauer, Ursula Reichart, Thomas Kolbe, Christian Bogdan, Tomas Leanderson, David Levy, Thomas Decker and Mathias Müller
Nature Immunology 4, 471–477
(May 2003); doi:10.1038/ni910
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research article
Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers
Eric C. Hsu, Belinda Hsi, Masami Hirota-Tsuchihara, Jurgen Ruland, Cathy Iorio, Farida Sarangi, Jingyu Diao, Giovanni Migliaccio, D. Lorne Tyrrell, Norman Kneteman and Christopher D. Richardson
Nature Biotechnology 21, 519–525
(May 2003); doi:10.1038/nbt817
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review
Microbial pathogenesis and cytoskeletal function
Samantha Gruenheid and B. Brett Finlay
Nature 422, 775–781
(17 April 2003); doi:10.1038/nature01603
| Summary | Full Text (HTML / PDF) |

review article
Radical causes of cancer
S. Perwez Hussain, Lorne J. Hofseth and Curtis C. Harris
Nature Reviews Cancer 3, 276–285
(April 2003); doi:10.1038/nrc1046
| Summary | Full Text (HTML / PDF) |

letter
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
Akihiro Fujikawa, Daisuke Shirasaka, Shoichi Yamamoto, Hiroyoshi Ota, Kinnosuke Yahiro, Masahide Fukada, Takafumi Shintani, Akihiro Wada, Nobuo Aoyama, Toshiya Hirayama, Hiroshi Fukamachi and Masaharu Noda
Nature Genetics 33, 375–381
(March 2003); doi:10.1038/ng1112
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news and views
Intoxicated cells and stomach ulcers
Richard M. Peek Jr.
Nature Genetics 33, 328–330
(March 2003); doi:10.1038/ng0303-328
| Full Text (HTML/PDF) |

article
Angiogenins: a new class of microbicidal proteins involved in innate immunity
Lora V. Hooper, Thaddeus S. Stappenbeck, Chieu V. Hong and Jeffrey I. Gordon
Nature Immunology 4, 269–273
(March 2003); doi:10.1038/ni888
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news and views
Angiogenin: an antimicrobial ribonuclease
Tomas Ganz
Nature Immunology 4, 213–214
(March 2003); doi:10.1038/ni0303-213
| Full Text (HTML/PDF) |

article
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases
Tracy A. Young, Benedicte Delagoutte, James A. Endrizzi, Arnold M. Falick and Tom Alber
Nature Structural Biology 10, 168–174
(March 2003); doi:10.1038/nsb897
| Abstract | Full Text (HTML/PDF) |

letter
Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency
Stéphanie Dupuis, Emmanuelle Jouanguy, Sami Al-Hajjar, Claire Fieschi, Ibrahim Zaid Al-Mohsen, Suliman Al-Jumaah, Kun Yang, Ariane Chapgier, Céline Eidenschenk, Pierre Eid, Abdulaziz Al Ghonaium, Haysam Tufenkeji, Husn Frayha, Suleiman Al-Gazlan, Hassan Al-Rayes, Robert D. Schreiber, Ion Gresser and Jean-Laurent Casanova
Nature Genetics 33, 388–391
(March 2003); doi:10.1038/ng1097
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perspectives
Timeline: Innate immune sensing and its roots: the story of endotoxin
Bruce Beutler and Ernst Th. Rietschel
Nature Reviews Immunology 3, 169–176
(February 2003); doi:10.1038/nri1004
| Summary | Full Text (HTML / PDF) |

article
Functional interactions between dendritic cells and NK cells during viral infection
Daniel M. Andrews, Anthony A. Scalzo, Wayne M. Yokoyama, Mark J. Smyth and Mariapia A. Degli-Esposti
Nature Immunology 4, 175–181
(February 2003); doi:10.1038/ni880
| Abstract | Full Text (HTML/PDF) |

review article
Hide, shield and strike back: how HIV-infected cells avoid immune eradication
B. Matija Peterlin and Didier Trono
Nature Reviews Immunology 3, 97–107
(February 2003); doi:10.1038/nri998
| Summary | Full Text (HTML / PDF) |

article
HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages
Elena Izmailova, Frederic M.N. Bertley, Qian Huang, Norbert Makori, Christopher J. Miller, Richard A. Young and Anna Aldovini
Nature Medicine 9, 191–197
(February 2003); doi:10.1038/nm822
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news and views
Tat's seductive side
Mario Stevenson
Nature Medicine 9, 163–164
(February 2003); doi:10.1038/nm0203-163
| Full Text (HTML/PDF) |

review article
Alternative activation of macrophages
Siamon Gordon
Nature Reviews Immunology 3, 23–35
(January 2003); doi:10.1038/nri978
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review article
Entry of viruses through the epithelial barrier: Pathogenic trickery
Morgane Bomsel and Annette Alfsen
Nature Reviews Molecular Cell Biology 4, 57–68
(January 2003); doi:10.1038/nrm1005
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news and views
Regulatory T cells: mediating compromises between host and parasite
Shimon Sakaguchi
Nature Immunology 4, 10–11
(January 2003); doi:10.1038/ni0103-10
| Full Text (HTML/PDF) |

review article
The dual-function CD150 receptor subfamily: the viral attraction
Svetlana P. Sidorenko and Edward A. Clark
Nature Immunology 4, 19–24
(January 2003); doi:10.1038/ni0103-19
| Abstract | Full Text (HTML/PDF) |

review article
Intracellular pathways of CD1 antigen presentation
D. Branch Moody and Steven A. Porcelli
Nature Reviews Immunology 3, 11–22
(January 2003); doi:10.1038/nri979
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review article
Viral mimicry of cytokines, chemokines and their receptors
Antonio Alcami
Nature Reviews Immunology 3, 36–50
(January 2003); doi:10.1038/nri980
| Summary | Full Text (HTML / PDF) |

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