 |
 |
|
|
 |
signaling update home | updates | news | research library | featured articles | conferences |
Research library: Mouse
2002: November | August | July | June | May | April | March | February | January
Other Years: 2003 | 2004 | 2005 | 2006 | 2007 | 2008
review article
The immunology of susceptibility and resistance to leishmania major in mice
David Sacks and Nancy Noben-Trauth
Nature Reviews Immunology 2, 845–858
(November 2002); doi:10.1038/nri933
| Summary | Full Text (HTML / PDF) |
article
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
Richard Sharp, Juan A. Recio, Chamelli Jhappan, Toshiyuki Otsuka, Shiquan Liu, Yanlin Yu, Wenjing Liu, Miriam Anver, Fariba Navid, Lee J. Helman, Ronald A. DePinho and Glenn Merlino
Nature Medicine 8, 1276–1280
(November 2002); doi:10.1038/nm787
| Abstract | Full Text (HTML/PDF) |
news and views
Muscling in on rhabdomyosarcoma
Webster K. Cavenee
Nature Medicine 8, 1200–1201
(November 2002); doi:10.1038/nm1102-1200
| Full Text (HTML/PDF) |
letters to nature
Progenitor cell maintenance requires numb and numblike during mouse neurogenesis
Petur H. Petersen, Kaiyong Zou, Joseph K. Hwang, Yuh Nung Jan and Weimin Zhong
Nature 419, 929–934
(31 October 2002); doi:10.1038/nature01124
| First Paragraph | Full Text (HTML / PDF) |
article
Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior
Douglas E. Vetter, Chien Li, Lingyun Zhao, Angelo Contarino, M. Charles Liberman, George W. Smith, Yelena Marchuk, George F. Koob, Stephen F. Heinemann, Wylie Vale and Kuo-Fen Lee
Nature Genetics 31, 363–369
(August 2002); doi:10.1038/ng914
| Abstract | Full Text (HTML/PDF) |
article
Functions of FGF signalling from the apical ectodermal ridge in limb development
Xin Sun, Francesca V. Mariani and Gail R. Martin
Nature 418, 501–508
(1 August 2002); doi:10.1038/nature00902
| Abstract | Full Text (HTML/PDF) |
letter to nature
Determination of left-right patterning of the mouse embryo by artificial nodal flow
Shigenori Nonaka, Hidetaka Shiratori, Yukio Saijoh and Hiroshi Hamada
Nature 418, 96–99
(5th July 2002); doi:10.1038/nature00849
| First Paragraph | Full Text (HTML/PDF) |
news and views
Embryology: Fluid flow and broken symmetry
Claudio D. Stern
Nature 418, 29–30
(5th July 2002); doi:10.1038/418029a
| Full Text (HTML/PDF) |
letter
Deletion in Catna2, encoding aN-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation
Chankyu Park, William Falls, Jacqueline H. Finger, Chantal M. Longo-Guess and Susan L. Ackerman
Nature Genetics 31, 279–284
(July 2002); doi:10.1038/ng908
| First Paragraph | Full Text (HTML/PDF) |
article
Loss of HIF-2a and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
Veerle Compernolle, Koen Brusselmans, Till Acker, Peter Hoet, Marc Tjwa, Heike Beck, Stéphane Plaisance, Yuval Dor, Eli Keshet, Florea Lupu, Benoit Nemery, Mieke Dewerchin, Paul Van Veldhoven, Karl Plate, Lieve Moons, Désiré Collen and Peter Carmeliet
Nature Medicine 8, 702–710
(July 2002); doi:10.1038/nm721
| Abstract | Full Text (HTML/PDF) |
review article
Organogenesis: Coordinating early kidney development: lessons from gene targeting
Seppo Vainio and Yanfeng Lin
Nature Reviews Genetics 3, 533–543
(July 2002); doi:10.1038/nrg842
| Abstract | Full Text (HTML/PDF) |
Letter
Placental-specific IGF-II is a major modulator of placental and fetal growth
Miguel Constância, Myriam Hemberger, Jennifer Hughes, Wendy Dean, Anne Ferguson-Smith, Reinald Fundele, Francesca Stewart, Gavin Kelsey, Abigail Fowden, Colin Sibley and Wolf Reik
Nature 417, 945–948
(June 2002); doi:10.1038/nature00819
| First Paragraph | Full Text (HTML/PDF) |
news and views
Genomic imprinting: Piece of cake
Benjamin Tycko and Argiris Efstratiadis
Nature 417, 913–914
(June 2002); doi:10.1038/417913a
| Full Text (HTML/PDF) |
letter to nature
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2
Manolis Pasparakis, Gilles Courtois, Martin Hafner, Marc Schmidt-Supprian, Arianna Nenci, Atiye Toksoy, Monika Krampert, Matthias Goebeler, Reinhard Gillitzer, Alain Israel, Thomas Krieg, Klaus Rajewsky and Ingo Haase
Nature 417, 861–866
(20 June 2002); doi:10.1038/nature00820
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Extensive and divergent circadian gene expression in liver and heart
Kai-Florian Storch, Ovidiu Lipan, Igor Leykin, N. Viswanathan, Fred C. Davis, Wing H. Wong & Charles J. Weitz
Nature 417, 78–83
(May 2002); doi:10.1038/nature744
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
Shan Zhu, Irina G. Stavrovskaya, Martin Drozda, Betty Y. S. Kim, Victor Ona, Mingwei Li, Satinder Sarang, Allen S. Liu, Dean M. Hartley, Du Chu Wu, Steven Gullans, Robert J. Ferrante, Serge Przedborski, Bruce S. Kristal and Robert M. Friedlander
Nature 417, 74–78
(May 2002); doi:10.1038/417074a
| First Paragraph | Full Text (HTML/PDF) |
article
Regulation of the TCRa repertoire by the survival window of CD4+CD8+ thymocytes
Jian Guo, Abbas Hawwari, Hong Li, Zuoming Sun, Sanjeev K. Mahanta, Dan R. Littman, Michael S. Krangel and You-Wen He
Nature Immunology 3, 469–476
(May 2002); doi:10.1038/ni791
| Abstract | Full Text (HTML/PDF) |
letter
Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development
Karen Niederreither, Suzan Abu-Abed, Brigitte Schuhbaur, Martin Petkovich, Pierre Chambon and Pascal Dollé
Nature Genetics 31, 84–88
(May 2002); doi:10.1038/ng876
| First Paragraph | Full Text (HTML/PDF) |
news and views
Retinoid metabolism: a balancing act
Thomas Perlmann
Nature Genetics 31, 7–9
(May 2002); doi:10.1038/ng877
| Full Text (HTML/PDF) |
article
Disruption of CREB function in brain leads to neurodegeneration
Theo Mantamadiotis, Thomas Lemberger, Susanne C. Bleckmann, Heidrun Kern, Oliver Kretz, Ana Martin Villalba, François Tronche, Christoph Kellendonk, Daniel Gau, Josef Kapfhammer, Christiane Otto, Wolfgang Schmid and Günther Schütz
Nature Genetics 31, 47–54
(May 2002); doi:10.1038/ng882
| Abstract | Full Text (HTML/PDF) |
article
Genetic analysis of the mouse brain proteome
Joachim Klose, Christina Nock, Marion Herrmann, Kai Stühler, Katrin Marcus, Martin Blüggel, Eberhard Krause, Leonard C. Schalkwyk, Sohaila Rastan, Steve D.M. Brown, Konrad Büssow, Hans Lehrach and Heinz Himmelbauer
Nature Genetics 30, 385–393
(April 2002); doi:10.1038/ng861
| Abstract | Full Text (HTML/PDF) |
letter
c-fos regulates neuronal excitability and survival
Jianhua Zhang, Dongsheng Zhang, Jill Slane McQuade, Michael Behbehani, Joe Z. Tsien and Ming Xu
Nature Genetics 30, 416–420
(April 2002); doi:10.1038/ng859
| First Paragraph | Full Text (HTML/PDF) |
letter
Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
Seung K. Kim, Licia Selleri, Joon S. Lee, Andrew Y. Zhang, Xueying Gu, Yakop Jacobs and Michael L. Cleary
Nature Genetics 30, 430–435
(April 2002); doi:10.1038/ng860
| First Paragraph | Full Text (HTML/PDF) |
letter
Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
A. Jeannine Lincoln, Dineli Wickramasinghe, Paula Stein, Richard M. Schultz, Mary Ellen Palko, Maria P. De De Miguel, Lino Tessarollo and Peter J. Donovan
Nature Genetics 30, 446–449
(April 2002); doi:10.1038/ng856
| First Paragraph | Full Text (HTML/PDF) |
article
CD39 is the dominant Langerhans cell-associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
Norikatsu Mizumoto, Tadashi Kumamoto, Simon C. Robson, Jean Sévigny, Hiroyuki Matsue, Keiichi Enjyoji and Akira Takashima
Nature Medicine 8, 358–365
(April 2002); doi:10.1038/nm0402-358
| Abstract | Full Text (HTML/PDF) |
news and views
The skinny on CD39 in immunity and inflammation
Richard D. Granstein
Nature Medicine 8, 336–338
(April 2002); doi:10.1038/nm0402-336
| Full Text (HTML/PDF) |
news and views
CREB family transcription factors inhibit neuronal suicide
Ted M. Dawson and David D. Ginty
Nature Medicine 8, 450–451
(May 2002); doi:10.1038/nm0502-450
| Full Text (HTML/PDF) |
review article
CONDITIONAL MOUSE MODELS OF SPORADIC CANCER
Jos Jonkers and Anton Berns
Nature Reviews Cancer 2, 251–265
(April 2002); doi:10.1038/nrc777
| Abstract | Full Text (HTML/PDF) |
letters to nature
RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-b
Hiroshi Takayanagi, Sunhwa Kim, Koichi Matsuo, Hiroshi Suzuki, Tomohiko Suzuki, Kojiro Sato, Taeko Yokochi, Hiromi Oda, Kozo Nakamura, Nobutaka Ida, Erwin F. Wagner and Tadatsugu Taniguchi
Nature 416, 744–749
(April 2002); doi:10.1038/416744a
| First Paragraph | Full Text (HTML/PDF) |
news and views
Medicine: Interfering with bone remodelling
Tamara Alliston and Rik Derynck
Nature 416, 686–687
(April 2002); doi:10.1038/416686a
| Full Text (HTML/PDF) |
article
Human Toll-like receptor 4 recognizes host-specific LPS modifications
Adeline M. Hajjar, Robert K. Ernst and Jeff H. Tsai, Christopher B. Wilson and Samuel I. Miller
Nature Immunology 3, 354–359
(April 2002); doi:10.1038/ni777
| Abstract | Full Text (HTML/PDF) |
letters to nature
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
Elsa R. Flores, Kenneth Y. Tsai, Denise Crowley, Shomit Sengupta, Annie Yang, Frank McKeon and Tyler Jacks
Nature 416, 560–564
(April 2002); doi:10.1038/416560a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Protein kinase Cd controls self-antigen-induced B-cell tolerance
Ingrid Mecklenbräuker, Kaoru Saijo, Nai-Ying Zheng, Michael Leitges and Alexander Tarakhovsky
Nature 416, 860–865
(April 2002); doi:10.1038/416860a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cd
Akitomo Miyamoto, Keiko Nakayama, Hiroyuki Imaki, Sachiko Hirose, Yi Jiang, Masaaki Abe, Tadasuke Tsukiyama, Hiroyasu Nagahama, Shigeo Ohno, Shigetsugu Hatakeyama and Keiichi I. Nakayama
Nature 416, 865–869
(April 2002); doi:10.1038/416865a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4
Thomas Boettger, Christian A. Hübner, Hannes Maier, Marco B. Rust, Franz X. Beck and Thomas J. Jentsch
Nature 416, 874–878
(April 2002); doi:10.1038/416874a
| First Paragraph | Full Text (HTML/PDF) |
article
CEACAM1 regulates insulin clearance in liver
Matthew N. Poy, Yan Yang, Khadijeh Rezaei, Mats A. Fernström, Abraham D. Lee, Yoshiaki Kido, Sandra K. Erickson and Sonia M. Najjar
Nature Genetics 30, 270–276
(March 2002); doi:10.1038/ng840
| Abstract | Full Text (HTML/PDF) |
news and views
Molecular physiology: Protecting the heart
Mark T. Nelson and Gerald M. Herrera
Nature 416, 273–274
(March 2002); doi:10.1038/416273a
| Full Text (HTML/PDF) |
letters to nature
Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy
Hong-Bo Xin, Takaaki Senbonmatsu, Dong-Sheng Cheng, Yong-Xiao Wang, Julio A. Copello, Guang-Ju Ji, Mei Lin Collier, Ke-Yu Deng, Loice H. Jeyakumar, Mark A. Magnuson, Tadashi Inagami, Michael I. Kotlikoff and Sidney Fleischer
Nature 416, 334–338
(March 2002); doi:10.1038/416334a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
Lili A. Barouch, Robert W. Harrison, Michel W. Skaf, Gisele O. Rosas, Thomas P. Cappola, Zoulficar A. Kobeissi, Ion A. Hobai, Christopher A. Lemmon, Arthur L. Burnett, Brian O'Rourke, E. Rene Rodriguez, Paul L. Huang, João A. C. Lima, Dan E. Berkowitz and Joshua M. Hare
Nature 416, 337–339
(March 2002); doi:10.1038/416005a
| First Paragraph | Full Text (HTML/PDF) |
review article
ESTABLISHMENT OF VERTEBRATE LEFT-RIGHT ASYMMETRY
Hiroshi Hamada, Chikara Meno, Daisuke Watanabe and Yukio Saijoh
Nature Reviews Genetics 3, 103–113
(February 2002); doi:10.1038/nrg732
| Abstract | Full Text (HTML/PDF) |
review article
TRANSGENIC ANALYSIS OF THYMOCYTE SIGNAL TRANSDUCTION
Doreen A. Cantrell
Nature Reviews Immunology 2, 20–27
(January 2002); doi:10.1038/nri703
| Abstract | Full Text (HTML/PDF) |
article
Enhanced pathological angiogenesis in mice lacking b3 integrin or b3 and b5 integrins
Louise E. Reynolds, Lorenza Wyder, Julie C. Lively, Daniela Taverna, Stephen D. Robinson, Xiaozhu Huang, Dean Sheppard, Richard O. Hynes and Kairbaan M. Hodivala-Dilke
Nature Medicine 8, 27–34
(January 2002); doi:10.1038/nm0102-27
| Abstract | Full Text (HTML/PDF) |
news and views
Integrin indecision
Peter Carmeliet
Nature Medicine 8, 14–16
(January 2002); doi:10.1038/nm0102-14
| Full Text (HTML/PDF) |
article
Interleukin-6-deficient mice develop mature-onset obesity
Ville Wallenius, Kristina Wallenius, Bo Ahrén, Mats Rudling, Hans Carlsten, Suzanne L. Dickson, Claes Ohlsson and John-Olov Jansson
Nature Medicine 8, 75–79
(January 2002); doi:10.1038/nm0102-75
| Abstract | Full Text (HTML/PDF) |
research article
Human T-lymphocyte cytotoxicity and proliferation directed by a single chimeric TCRz /CD28 receptor
John Maher, Renier J. Brentjens, Gertrude Gunset, Isabelle Rivière and Michel Sadelain
Nature Biotechnology 20, 70–75
(January 2002); doi:10.1038/nbt0102-70
| Abstract | Full Text (HTML/PDF) |
letters to nature
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia, Akemi Ryu, Hanspeter Waldner, Tatyana Chernova, Stephen Manning, Edward A. Greenfield, Anthony J. Coyle, Raymond A. Sobel, Gordon J. Freeman and Vijay K. Kuchroo
Nature 415, 536–541
(January 2002); doi:10.1038/415536a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1
Rui M. Costa, Nikolai B. Federov, Jeff H. Kogan, Geoffrey G. Murphy, Joel Stern, Masuo Ohno, Raju Kucherlapati, Tyler Jacks and Alcino J. Silva
Nature 415, 526–530
(January 2002); doi:10.1038/nature711
| First Paragraph | Full Text (HTML/PDF) |
news and views
Ageing: The price of tumour suppression?
Gerardo Ferbeyre and Scott W. Lowe
Nature 415, 26–27
(January 2002); doi:10.1038/415026a
| Full Text (HTML/PDF) |
article
p53 mutant mice that display early ageing-associated phenotypes
Stuart D. Tyner, Sundaresan Venkatachalam, Jene Choi, Stephen Jones, Nader Ghebranious, Herbert Igelmann, Xiongbin Lu, Gabrielle Soron, Benjamin Cooper, Cory Brayton, Sang Hee Park, Timothy Thompson, Gerard Karsenty, Allan Bradley and Lawrence A. Donehower
Nature 415, 45–53
(January 2002); doi:10.1038/415045a
| Summary | Full Text (HTML/PDF) |
letters to nature
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo
Hiromi Yanagisawa, Elaine C. Davis, Barry C. Starcher, Takashi Ouchi, Masashi Yanagisawa, James A. Richardson and Eric N. Olson
Nature 415, 168–171
(January 2002); doi:10.1038/415168a
| First Paragraph | Full Text (HTML/PDF) |
letters to nature
Fibulin-5/DANCE is essential for elastogenesis in vivo
Tomoyuki Nakamura, Pilar Ruiz Lozano, Yasuhiro Ikeda, Yoshitaka Iwanaga, Aleksander Hinek, Susumu Minamisawa, Ching-Feng Cheng, Kazuhiro Kobuke, Nancy Dalton, Yoshikazu Takada, Kei Tashiro, John Ross Jr, Tasuku Honjo and Kenneth R. Chien
Nature 415, 171–175
(January 2002); doi:10.1038/415171a
| First Paragraph | Full Text (HTML/PDF) |
HOME | SIGNALING UPDATE | MOLECULE PAGES | DATA CENTER | ABOUT US
registration | e-alert | help | contact us | site guide | search