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Research library: Neurobiology

2005: December | November | October | September | August | July | June | May | April | March | February | January

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letter
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
Ragnhildur Káradóttir, Pauline Cavelier, Linda H. Bergersen and David Attwell
Nature 438, 1162–1166
(22 December 2005); doi:10.1038/nature04302
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NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Michael G. Salter and Robert Fern
Nature 438, 1167–1171
(22 December 2005); doi:10.1038/nature04301
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article
FARP2 triggers signals for Sema3A-mediated axonal repulsion
Toshihiko Toyofuku, Junko Yoshida, Tamiko Sugimoto, Hong Zhang, Atsushi Kumanogoh, Masatsugu Hori and Hitoshi Kikutani
Nature Neuroscience 8, 1712–1719
(December 2005); doi:10.1038/nn1596
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news and views
Tinker to Evers to Chance: semaphorin signaling takes teamwork
Paul A Garrity
Nature Neuroscience 8, 1635–1636
(December 2005); doi:10.1038/nn1205-1635
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BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
Jeffrey A. M. Coull , Simon Beggs, Dominic Boudreau, Dominick Boivin, Makoto Tsuda, Kazuhide Inoue, Claude Gravel, Michael W. Salter and Yves De Koninck
Nature 438, 1017–1021
(15 December 2005); doi:10.1038/nature04223
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article
IKK mediates ischemia-induced neuronal death
Oliver Herrmann, Bernd Baumann, Rossana de Lorenzi, Sajjad Muhammad, Wen Zhang, Jens Kleesiek, Max Malfertheiner, Martin Köhrmann, Ioana Potrovita, Ira Maegele, Cordian Beyer, James R Burke, Mazahir T Hasan, Hermann Bujard, Thomas Wirth, Manolis Pasparakis and Markus Schwaninger
Nature Medicine 11, 1322–1329
(December 2005); doi:10.1038/nm1323
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brief communication
The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone
Anna-Kaisa Anttonen, Ibrahim Mahjneh, Riikka H Hämäläinen, Clotilde Lagier-Tourenne, Outi Kopra, Laura Waris, Mikko Anttonen, Tarja Joensuu, Hannu Kalimo, Anders Paetau, Lisbeth Tranebjaerg, Denys Chaigne, Michel Koenig, Orvar Eeg-Olofsson, Bjarne Udd, Mirja Somer, Hannu Somer and Anna-Elina Lehesjoki
Nature Genetics 37, 1309–1311
(December 2005); doi:10.1038/ng1677
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brief communication
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
Jan Senderek, Michael Krieger, Claudia Stendel, Carsten Bergmann, Markus Moser, Nico Breitbach-Faller, Sabine Rudnik-Schöneborn, Astrid Blaschek, Nicole I Wolf, Inga Harting, Kathryn North, Janine Smith, Francesco Muntoni, Martin Brockington, Susana Quijano-Roy, Francis Renault, Ralf Herrmann, Linda M Hendershot, J Michael Schröder, Hanns Lochmüller, Haluk Topaloglu, Thomas Voit, Joachim Weis, Friedrich Ebinger and Klaus Zerres
Nature Genetics 37, 1312–1314
(December 2005); doi:10.1038/ng1678
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news and views
SILencing misbehaving proteins
Huda Y Zoghbi
Nature Genetics 37, 1302–1303
(December 2005); doi:10.1038/ng1205-1302
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article
mPins modulates PSD-95 and SAP102 trafficking and influences NMDA receptor surface expression
Nathalie Sans, Philip Y. Wang, Quansheng Du, Ronald S. Petralia, Ya-Xian Wang, Sajan Nakka, Joe B. Blumer, Ian G. Macara and Robert J. Wenthold
Nature Cell Biology 7, 1179–1190
(December 2005); doi:10.1038/ncb1325
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news and views
Pins for spines
Juergen A. Knoblich
Nature Cell Biology 7, 1157–1158
(December 2005); doi:10.1038/ncb1205-1057
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article
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2
Sohail F Tavazoie, Veronica A Alvarez, Dennis A Ridenour, David J Kwiatkowski and Bernardo L Sabatini
Nature Neuroscience 8, 1727–1734
(December 2005); doi:10.1038/nn1566
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review article
Signalling in development: Bone morphogenetic protein signalling and vertebrate nervous system development
Aimin Liu and Lee A. Niswander
Nature Reviews Neuroscience 6, 945–954
(December 2005); doi:10.1038/nrn1805
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letter
Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
Iiris Hovatta, Richard S. Tennant, Robert Helton, Robert A. Marr, Oded Singer, Jeffrey M. Redwine, Julie A. Ellison, Eric E. Schadt, Inder M. Verma, David J. Lockhart and Carrolee Barlow
Nature 438, 662–666
(01 December 2005); doi:10.1038/nature04250
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article
NMDA receptors regulate developmental gap junction uncoupling via CREB signaling
Harsha Arumugam, Xinhuai Liu, Paul J Colombo, Roderick A Corriveau and Andrei B Belousov
Nature Neuroscience 8, 1720–1726
(December 2005); doi:10.1038/nn1588
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news and views
Flipping the switch from electrical to chemical communication
Karl Kandler and Edda Thiels
Nature Neuroscience 8, 1633–1634
(December 2005); doi:10.1038/nn1205-1633
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Phosphatidylinositol transfer protein-α in netrin-1-induced PLC signalling and neurite outgrowth
Yi Xie, Yu-Qiang Ding, Yan Hong, Zhu Feng, Sammy Navarre, Cai-Xia Xi, Xiao-Juan Zhu, Chun-Lei Wang, S. L. Ackerman, David Kozlowski, Lin Mei and Wen-Cheng Xiong
Nature Cell Biology 7, 1124–1132
(November 2005); doi:10.1038/ncb1321
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news and views
Netrin PIPes up
Patrick Mehlen and Agnès Bernet
Nature Cell Biology 7, 1052–1053
(November 2005); doi:10.1038/ncb1105-1052
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news and views
Senseless makes sense for spinocerebellar ataxia-1
Vikram Khurana, Tudor A Fulga and Mel B Feany
Nature Neuroscience 8, 1422–1424
(November 2005); doi:10.1038/nn1105-1422
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review article
Axon degeneration mechanisms: commonality amid diversity
Michael Coleman
Nature Reviews Neuroscience 6, 889–898
(November 2005); doi:10.1038/nrn1788
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Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube
Yuko Muroyama, Yuko Fujiwara, Stuart H. Orkin and David H. Rowitch
Nature 438, 360–363
(17 November 2005); doi:10.1038/nature04139
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article
Drosophila melanogaster homolog of Down syndrome critical region 1 is critical for mitochondrial function
Karen T Chang and Kyung-Tai Min
Nature Neuroscience 8, 1577–1585
(November 2005); doi:10.1038/nn1564
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article
Subunit arrangement and function in NMDA receptors
Hiroyasu Furukawa, Satinder K Singh, Romina Mancusso and Eric Gouaux
Nature 438, 185–192
(10 November 2005); doi:10.1038/nature04089
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Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival
Elizabeth Allen, Jianqing Ding, Wei Wang, Suneet Pramanik, Jonathan Chou, Vincent Yau and Yanmin Yang
Nature 438, 224–228
(10 November 2005); doi:10.1038/nature04256
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Fruitless specifies sexually dimorphic neural circuitry in the Drosophila brain
Ken-Ichi Kimura, Manabu Ote, Tatsunori Tazawa and Daisuke Yamamoto
Nature 438, 229–233
(10 November 2005); doi:10.1038/nature04229
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Principal pathway coupling agonist binding to channel gating in nicotinic receptors
Won Yong Lee and Steven M. Sine
Nature 438, 243–247
(10 November 2005); doi:10.1038/nature04156
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Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
Sarah C. R. Lummis, Darren L. Beene, Lori W. Lee, Henry A. Lester, R. William Broadhurst and Dennis A. Dougherty
Nature 438, 248–252
(10 November 2005); doi:10.1038/nature04130
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article
Dopamine covalently modifies and functionally inactivates parkin
Matthew J LaVoie, Beth L Ostaszewski, Andreas Weihofen, Michael G Schlossmacher and Dennis J Selkoe
Nature Medicine 11, 1214–1221
(November 2005); doi:10.1038/nm1314
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news and views
Neurons inflict self-harm
Mark R Cookson
Nature Medicine 11, 1159–1161
(November 2005); doi:10.1038/nm1105-1159
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review article
Mitochondrial uncoupling proteins in the CNS: in support of function and survival
Zane B. Andrews, Sabrina Diano and Tamas L. Horvath
Nature Reviews Neuroscience 6, 829–840
(November 2005); doi:10.1038/nrn1767
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The transcription factor Engrailed-2 guides retinal axons
Isabelle Brunet, Christine Weinl, Michael Piper, Alain Trembleau, Michel Volovitch, William Harris, Alain Prochiantz and Christine Holt
Nature 438, 94–98
(03 November 2005); doi:10.1038/nature04110
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Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin
Marcus O. W. Grimm, Heike S. Grimm, Andreas J. Pätzold, Eva G. Zinser, Riikka Halonen, Marco Duering, Jakob-A. Tschäpe, Bart De Strooper, Ulrike Müller, Jie Shen and Tobias Hartmann
Nature Cell Biology 7, 1118–1123
(November 2005); doi:10.1038/ncb1313
| Abstract | Full Text (HTML / PDF) |

news and views
Alzheimer peptides perturb lipid-regulating enzymes
Mark P. Mattson, Roy G. Cutler and Dong-Gyu Jo
Nature Cell Biology 7, 1045–1047
(November 2005); doi:10.1038/ncb1105-1045
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article
Cbln1 is essential for synaptic integrity and plasticity in the cerebellum
Hirokazu Hirai, Zhen Pang, Dashi Bao, Taisuke Miyazaki, Leyi Li, Eriko Miura, Jennifer Parris, Yongqi Rong, Masahiko Watanabe, Michisuke Yuzaki and James I Morgan
Nature Neuroscience 8, 1534–1541
(November 2005); doi:10.1038/nn1576
| Abstract | Full Text (HTML / PDF) |

news and views
How neurons keep in touch
Fekrije Selimi and Nathaniel Heintz
Nature Neuroscience 8, 1417–1418
(November 2005); doi:10.1038/nn1105-1417
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review article
Pathways modulating neural KCNQ/M (Kv7) potassium channels
Patrick Delmas and David A. Brown
Nature Reviews Neuroscience 6, 850–862
(November 2005); doi:10.1038/nrn1785
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Wnt signalling regulates adult hippocampal neurogenesis
Dieter-Chichung Lie, Sophia A. Colamarino, Hong-Jun Song, Laurent Désiré, Helena Mira, Antonella Consiglio, Edward S. Lein, Sebastian Jessberger, Heather Lansford, Alejandro R. Dearie and Fred H. Gage
Nature 437, 1370–1375
(27 October 2005); doi: 10.1038/nature04108
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article
Regulation of aversion to noxious food by Drosophila neuropeptide Y- and insulin-like systems
Qi Wu, Zhangwu Zhao and Ping Shen
Nature Neuroscience 8, 1350–1355
(October 2005); doi:10.1038/nn1540
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article
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
Masahiro Waza, Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, Chen Sang, Fumiaki Tanaka, Akira Inukai, Manabu Doyu and Gen Sobue
Nature Medicine 11, 1088–1095
(October 2005); doi:10.1038/nm1298
| Abstract | Full Text (HTML/PDF) |

article
Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity
Jacques I Wadiche and Craig E Jahr
Nature Neuroscience 8, 1329–1334
(October 2005); doi:10.1038/nn1539
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article
SFRP1 regulates the growth of retinal ganglion cell axons through the Fz2 receptor
Josana Rodriguez, Pilar Esteve, Christine Weinl, José María Ruiz, Yasmín Fermin, Françoise Trousse, Asha Dwivedy, Christine Holt and Paola Bovolenta
Nature Neuroscience 8, 1301–1309
(October 2005); doi:10.1038/nn1547
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news and views
A no-Wnt situation: SFRPs as axon guidance molecules
Uwe Drescher
Nature Neuroscience 8, 1281–1282
(October 2005); doi:10.1038/nn1005-1281
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In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
Sohyun Ahn and Alexandra L. Joyner
Nature 437, 894–897
(06 October 2005); doi:10.1038/nature03994
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article
Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model
Oded Singer, Robert A Marr, Edward Rockenstein, Leslie Crews, Nicole G Coufal, Fred H Gage, Inder M Verma and Eliezer Masliah
Nature Neuroscience 8, 1343–1349
(October 2005); doi:10.1038/nn1531
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review article
Metabotropic glutamate receptors in the basal ganglia motor circuit
P. Jeffrey Conn, Giuseppe Battaglia, Michael J. Marino and Ferdinando Nicoletti
Nature Reviews Neuroscience 6, 787–798
(October 2005); doi:10.1038/nrn1763
| Abstract | Full Text (HTML / PDF) |

article
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis
Petra Van Damme, Lennart Martens, Jozef Van Damme, Koen Hugelier, An Staes, Joël Vandekerckhove and Kris Gevaert
Nature Methods 2, 771–777
(October 2005); doi:10.1038/nmeth792
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article
An astrocytic basis of epilepsy
Guo-Feng Tian, Hooman Azmi, Takahiro Takano, Qiwu Xu, Weiguo Peng, Jane Lin, NancyAnn Oberheim, Nanhong Lou, Xiaohai Wang, H Ronald Zielke, Jian Kang and Maiken Nedergaard
Nature Medicine 11, 973–981
(September 2005); doi:10.1038/nm1277
| Abstract | Full Text (HTML/PDF) |

news and views
Astrocytes get in the act in epilepsy
Michael A Rogawski
Nature Medicine 11, 919–920
(September 2005); doi:10.1038/nm0905-919
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brief communication
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus
Judit K Makara, Marco Mor, Darren Fegley, Szilárd I Szabó, Satish Kathuria, Giuseppe Astarita, Andrea Duranti, Andrea Tontini, Giorgio Tarzia, Silvia Rivara, Tamás F Freund and Daniele Piomelli
Nature Neuroscience 8, 1139–1141
(September 2005); doi:10.1038/nn1521
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review article
Can we Develop Neurally Acting Drugs for the Treatment of Migraine?
Peter J. Goadsby
Nature Reviews Drug Discovery 4, 741–750
(September 2005); doi:10.1038/nrd1822
| Abstract | Full Text (HTML / PDF) |

letter
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
Lihong Zhao, Chantal Longo-Guess, Belinda S Harris, Jeong-Woong Lee and Susan L Ackerman
Nature Genetics 37, 974–979
(September 2005); doi:10.1038/ng1620
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article
Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
Xiuxin Liu, Qin Wang, Tarik F Haydar and Angélique Bordey
Nature Neuroscience 8, 1179–1187
(September 2005); doi:10.1038/nn1522
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news and views
GABA puts the brake on stem cells
Arnold R Kriegstein
Nature Neuroscience 8, 1132–1133
(September 2005); doi:10.1038/nn0905-1132
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review article
The origin and development of glial cells in peripheral nerves
Kristjan R. Jessen and Rhona Mirsky
Nature Reviews Neuroscience 6, 671–682
(September 2005); doi:10.1038/nrn1746
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article
Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation
Stephen A Back, Therese M F Tuohy, Hanqin Chen, Nicholas Wallingford, Andrew Craig, Jaime Struve, Ning Ling Luo, Fatima Banine, Ying Liu, Ansi Chang, Bruce D Trapp, Bruce F Bebo,, Jr. Mahendra S Rao and Larry S Sherman
Nature Medicine 11, 966–972
(September 2005); doi:10.1038/nm1279
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article
Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells
Rudolf Götz, Stefan Wiese, Shinichi Takayama, Guadalupe C Camarero, Wilfried Rossoll, Ulrich Schweizer, Jakob Troppmair, Sibylle Jablonka, Bettina Holtmann, John C Reed, Ulf R Rapp and Michael Sendtner
Nature Neuroscience 8, 1169–1178
(September 2005); doi:10.1038/nn1524
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article
Determination of absolute protein numbers in single synapses by a GFP-based calibration technique
Yoshiko Sugiyama, Izumi Kawabata, Kenji Sobue and Shigeo Okabe
Nature Methods 2, 677–684
(September 2005); doi:10.1038/nmeth783
| Abstract | Full Text (HTML/PDF) |

letter
Translational control of hippocampal synaptic plasticity and memory by the eIF2α kinase GCN2
Mauro Costa-Mattioli, Delphine Gobert, Heather Harding, Barbara Herdy, Mounia Azzi, Martin Bruno, Michael Bidinosti, Cyrinne Ben Mamou, Edwige Marcinkiewicz, Madoka Yoshida, Hiroaki Imataka, A. Claudio Cuello, Nabil Seidah, Wayne Sossin, Jean-Claude Lacaille, David Ron, Karim Nader and Nahum Sonenberg
Nature 436, 1166–1173
(25 August 2005); doi:10.1038/nature03897
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article
Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway
Wouter J de Jonge, Esmerij P van der Zanden, Frans O The, Maarten F Bijlsma, David J van Westerloo, Roelof J Bennink, Hans-Rudolf Berthoud, Satoshi Uematsu, Shizuo Akira, Rene M van den Wijngaard and Guy E Boeckxstaens
Nature Immunology 6, 844–851
(August 2005); doi:10.1038/ni1229
| Abstract | Full Text (HTML/PDF) |

news and views
It takes nerve to dampen inflammation
Christine N Metz and Kevin J Tracey
Nature Immunology 6, 756–757
(August 2005); doi:10.1038/ni0805-756
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review article
Functions and mechanisms of retrograde neurotrophin signalling
Larry S. Zweifel, Rejji Kuruvilla and David D. Ginty
Nature Reviews Neuroscience 6, 615–625
(August 2005); doi:10.1038/nrn1727
| Summary | Full Text (HTML / PDF) |

letter
Local translation of RhoA regulates growth cone collapse
Karen Y. Wu, Ulrich Hengst, Llewellyn J. Cox, Evan Z. Macosko, Andreas Jeromin, Erica R. Urquhart and Samie R. Jaffrey
Nature 436, 1020–1024
(18 August 2005); doi:10.1038/nature03885
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review article
Interleukin-1 and neuronal injury
Stuart M. Allan, Pippa J. Tyrrell and Nancy J. Rothwell
Nature Reviews Immunology 5, 629–640
(August 2005); doi:10.1038/nri1664
| Abstract | Full Text (HTML / PDF) |

article
Nova regulates brain-specific splicing to shape the synapse
Jernej Ule, Alja Ule, Joanna Spencer, Alan Williams, Jing-Shan Hu, Melissa Cline, Hui Wang, Tyson Clark, Claire Fraser, Matteo Ruggiu, Barry R Zeeberg, David Kane, John N Weinstein, John Blume and Robert B Darnell
Nature Genetics 37, 844–852
(August 2005); doi:10.1038/ng1610
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news and views
Splicing on the brain
Benjamin J Blencowe
Nature Genetics 37, 796–797
(August 2005); doi:10.1038/ng0805-796
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article
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
Newton H Woo, Henry K Teng, Chia-Jen Siao, Cristina Chiaruttini, Petti T Pang, Teresa A Milner, Barbara L Hempstead and Bai Lu
Nature Neuroscience 8, 1069–1077
(August 2005); doi:10.1038/nn1510
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article
Regulation of NMDA receptor trafficking by amyloid-β
Eric M Snyder, Yi Nong, Claudia G Almeida, Surojit Paul, Timothy Moran, Eun Young Choi, Angus C Nairn, Michael W Salter, Paul J Lombroso, Gunnar K Gouras and Paul Greengard
Nature Neuroscience 8, 1051–1058
(August 2005); doi:10.1038/nn1503
| Abstract | Full Text (HTML/PDF) |

news and views
The synaptic Aβ hypothesis of Alzheimer disease
Rudolph E Tanzi
Nature Neuroscience 8, 977–979
(August 2005); doi:10.1038/nn0805-977
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review article
The yin and yang of neurotrophin action
Bai Lu, Petti T. Pang and Newton H. Woo
Nature Reviews Neuroscience 6, 603–614
(August 2005); doi:10.1038/nrn1726
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article
Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses
Wade Morishita, Helene Marie and Robert C Malenka
Nature Neuroscience 8, 1043–1050
(August 2005); doi:10.1038/nn1506
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review article
The vagus nerve and the nicotinic anti-inflammatory pathway
Luis Ulloa
Nature Reviews Drug Discovery 4, 673–684
(August 2005); doi:10.1038/nrd1797
| Abstract | Full Text (HTML / PDF) |

article
Systematic analysis of genes required for synapse structure and function
Derek Sieburth, QueeLim Ch'ng, Michael Dybbs, Masoud Tavazoie, Scott Kennedy, Duo Wang, Denis Dupuy, Jean-François Rual, David E. Hill, Marc Vidal, Gary Ruvkun and Joshua M. Kaplan
Nature 436, 510–517
(28 July 2005); doi:10.1038/nature03809
| Abstract | Full Text (HTML / PDF) |

news and views
Neuroscience: Genomics reaches the synapse
Cori Bargmann
Nature 436, 473–474
(28 July 2005); doi:10.1038/436473a
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letter
Dynein mutations impair autophagic clearance of aggregate-prone proteins
Brinda Ravikumar, Abraham Acevedo-Arozena, Sara Imarisio, Zdenek Berger, Coralie Vacher, Cahir J O'Kane, Steve D M Brown and David C Rubinsztein
Nature Genetics 37, 771–776
(July 2005); doi:10.1038/ng1591
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article
PI3 kinase signaling is required for retrieval and extinction of contextual memory
Xi Chen, Michael G Garelick, Hongbing Wang, Vicky Li, Jaime Athos and Daniel R Storm
Nature Neuroscience 8, 925–931
(July 2005); doi:10.1038/nn1482
| Abstract | Full Text (HTML/PDF) |

review article
Neurosteroids: endogenous regulators of the GABAA receptor
Delia Belelli and Jeremy J. Lambert
Nature Reviews Neuroscience 6, 565–575
(July 2005); doi:10.1038/nrn1703
| Abstract | Full Text (HTML / PDF) |

letter
Male-specific fruitless specifies the neural substrates of Drosophila courtship behaviour
Devanand S. Manoli, Margit Foss, Adriana Villella, Barbara J. Taylor, Jeffrey C. Hall and Bruce S. Baker
Nature 436, 395–400
(21 July 2005); doi:10.1038/nature03859
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letter
EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus
Oscar A. Negrete, Ernest L. Levroney, Hector C. Aguilar, Andrea Bertolotti-Ciarlet, Ronen Nazarian, Sara Tajyar and Benhur Lee
Nature 436, 401–405
(21 July 2005); doi:10.1038/nature03838
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brief communication
Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia
Takaharu Taketomi, Daigo Yoshiga, Koji Taniguchi, Takashi Kobayashi, Atsushi Nonami, Reiko Kato, Mika Sasaki, Atsuo Sasaki, Hitoshi Ishibashi, Maiko Moriyama, Kei-ichiro Nakamura, Junji Nishimura and Akihiko Yoshimura
Nature Neuroscience 8, 855–857
(July 2005); doi:10.1038/nn1485
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article
Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization
Katherine L Holton, Merewyn K Loder and Haley E Melikian
Nature Neuroscience 8, 881–888
(July 2005); doi:10.1038/nn1478
| Abstract | Full Text (HTML/PDF) |

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Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
Stefano Pluchino, Lucia Zanotti, Barbara Rossi, Elena Brambilla, Linda Ottoboni, Giuliana Salani, Marianna Martinello, Alessandro Cattalini, Alessandra Bergami, Roberto Furlan, Giancarlo Comi, Gabriela Constantin and Gianvito Martino
Nature 436, 266–271
(14 July 2005); doi:10.1038/nature03889
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review article
Common mechanisms of nerve and blood vessel wiring
Peter Carmeliet and Marc Tessier-Lavigne
Nature 436, 193–200
(14 July 2005); doi:10.1038/nature03875
| Summary | Full Text (HTML / PDF) |

article
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking
Casper C Hoogenraad, Aaron D Milstein, Iryna M Ethell, Mark Henkemeyer and Morgan Sheng
Nature Neuroscience 8, 906–915
(July 2005); doi:10.1038/nn1487
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news and views
EphB2 gets a GRIP on the dendritic arbor
Charu Misra and Edward B Ziff
Nature Neuroscience 8, 848–850
(July 2005); doi:10.1038/nn0705-848
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brief communication
Dominant role of the GluR2 subunit in regulation of AMPA receptors by CaMKII
Michael C Oh and Victor A Derkach
Nature Neuroscience 8, 853–854
(July 2005); doi:10.1038/nn1476
| First Paragraph | Full Text (HTML/PDF) |

letter
Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors
U. Maskos, B. E. Molles, S. Pons, M. Besson, B. P. Guiard, J.-P. Guilloux, A. Evrard, P. Cazala, A. Cormier, M. Mameli-Engvall, N. Dufour, I. Cloëz-Tayarani, A.-P. Bemelmans, J. Mallet, A. M. Gardier, V. David, P. Faure, S. Granon and J.-P. Changeux
Nature 436, 103–107
(07 July 2005); doi:10.1038/nature03694
| First Paragraph | Full Text (HTML / PDF) |

news and views
Neuroscience: A home for the nicotine habit
Julie A. Kauer
Nature 436, 31–32
(07 July 2005); doi:10.1038/436031a
| Full Text (HTML / PDF) |

letter
ATP is a mediator of chemosensory transduction in the central nervous system
Alexander V. Gourine, Enrique Llaudet, Nicholas Dale and K. Michael Spyer
Nature 436, 108–111
(07 July 2005); doi:10.1038/nature03690
| First Paragraph | Full Text (HTML / PDF) |

news and views
Huntingtin and the vicious circle
Jack Horne
Nature Cell Biology 7, 650
(July 2005); doi:10.1038/ncb0705-650
| Full Text (HTML/PDF) |

article
DNER acts as a neuron-specific Notch ligand during Bergmann glial development
Mototsugu Eiraku, Akira Tohgo, Katsuhiko Ono, Megumi Kaneko, Kazuto Fujishima, Tomoo Hirano and Mineko Kengaku
Nature Neuroscience 8, 873–880
(July 2005); doi:10.1038/nn1492
| Abstract | Full Text (HTML/PDF) |

review article
Role of the Immune system in chronic pain
Fabien Marchand, Mauro Perretti and Stephen B. McMahon
Nature Reviews Neuroscience 6, 521–532
(July 2005); doi:10.1038/nrn1700
| Summary | Full Text (HTML / PDF) |

letter
Ephrin signalling controls brain size by regulating apoptosis of neural progenitors
Vanessa Depaepe, Nathalie Suarez-Gonzalez, Audrey Dufour, Lara Passante, Jessica A Gorski, Kevin R. Jones, Catherine Ledent and Pierre Vanderhaeghen
Nature 435, 1244–1250
(30 June 2005); doi:10.1038/nature03651
| First Paragraph | Full Text (HTML/PDF) |

article
Reversible blockade of experience-dependent plasticity by calcineurin in mouse visual cortex
Yupeng Yang, Quentin S Fischer, Ying Zhang, Karsten Baumgärtel, Isabelle M Mansuy and Nigel W Daw
Nature Neuroscience 8, 791–796
(June 2005); doi:10.1038/nn1464
| Abstract | Full Text (HTML/PDF) |

review article
Developmental Cell Biology: Eph receptor signalling casts a wide net on cell behaviour
Elena B. Pasquale
Nature Reviews Molecular Cell Biology 6, 462–475
(June 2005); doi:10.1038/nrm1662
| Summary | Full Text (HTML / PDF) |

article
LINGO-1 negatively regulates myelination by oligodendrocytes
Sha Mi, Robert H Miller, Xinhua Lee, Martin L Scott, Svetlane Shulag-Morskaya, Zhaohui Shao, Jufang Chang, Greg Thill, Melissa Levesque, Mingdi Zhang, Cathy Hession, Dinah Sah, Bruce Trapp, Zhigang He, Vincent Jung, John M McCoy and R Blake Pepinsky
Nature Neuroscience 8, 745–751
(June 2005); doi:10.1038/nn1460
| Abstract | Full Text (HTML/PDF) |

brief communication
Laminin stimulates and guides axonal outgrowth via growth cone myosin II activity
Stephen G Turney and Paul C Bridgman
Nature Neuroscience 8, 717–719
(June 2005); doi:10.1038/nn1466
| First Paragraph | Full Text (HTML/PDF) |

article
RNA editing produces glycine receptor α3P185L, resulting in high agonist potency
Jochen C Meier, Christian Henneberger, Igor Melnick, Claudia Racca, Robert J Harvey, Uwe Heinemann, Volker Schmieden and Rosemarie Grantyn
Nature Neuroscience 8, 736–744
(June 2005); doi:10.1038/nn1467
| Abstract | Full Text (HTML/PDF) |

article
SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability
Narendrakumar Ramanan, Ying Shen, Sarah Sarsfield, Thomas Lemberger, Günther Schütz, David J Linden and David D Ginty
Nature Neuroscience 8, 759–767
(June 2005); doi:10.1038/nn1462
| Abstract | Full Text (HTML/PDF) |

article
Endocannabinoid signaling depends on the spatial pattern of synapse activation
Païkan Marcaggi and David Attwell
Nature Neuroscience 8, 776–781
(June 2005); doi:10.1038/nn1458
| Abstract | Full Text (HTML/PDF) |

review article
Notch signaling in the mammalian central nervous system: insights from mouse mutants
Keejung Yoon and Nicholas Gaiano
Nature Neuroscience 8, 709–715
(June 2005); doi:10.1038/nn1475
| Abstract | Full Text (HTML/PDF) |

article
Asymmetric membrane ganglioside sialidase activity specifies axonal fate
Jorge Santos Da Silva, Takafumi Hasegawa, Taeko Miyagi, Carlos G Dotti and Jose Abad-Rodriguez
Nature Neuroscience 8, 606–615
(May 2005); doi:10.1038/nn1442
| Abstract | Full Text (HTML/PDF) |

news and views
Axon formation: fate versus growth
Hui Jiang and Yi Rao
Nature Neuroscience 8, 544–546
(May 2005); doi:10.1038/nn0505-544
| Full Text (HTML/PDF) |

research article
Quantitative mouse brain proteomics using culture-derived isotope tags as internal standards
Yasushi Ishihama, Toshitaka Sato, Tsuyoshi Tabata, Norimasa Miyamoto, Koji Sagane, Takeshi Nagasu and Yoshiya Oda
Nature Biotechnology 23, 617–621
(May 2005); doi:10.1038/nbt1086
| First Paragraph | Full Text (HTML/PDF) |

article
α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
Li Chen and Mel B Feany
Nature Neuroscience 8, 657–663
(May 2005); doi:10.1038/nn1443
| Abstract | Full Text (HTML/PDF) |

research article
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
Viviane Tabar, Georgia Panagiotakos, Edward D Greenberg, Bill K Chan, Michel Sadelain, Philip H Gutin and Lorenz Studer
Nature Biotechnology 23, 601–606
(May 2005); doi:10.1038/nbt1088
| First Paragraph | Full Text (HTML/PDF) |

letter
EphrinB-EphB signalling regulates clathrin-mediated endocytosis through tyrosine phosphorylation of synaptojanin 1
Fumitoshi Irie, Misako Okuno, Elena B. Pasquale and Yu Yamaguchi
Nature Cell Biology 7, 501–509
(May 2005); doi:10.1038/ncb1252
| First Paragraph | Full Text (HTML/PDF) |

news and views
Ephrin tempers two-faced synaptojanin 1
Neil A. Hopper and Vincent O'Connor
Nature Cell Biology 7, 454–456
(May 2005); doi:10.1038/ncb0505-454
| Full Text (HTML/PDF) |

article
Gβγ acts at the C terminus of SNAP-25 to mediate presynaptic inhibition
Tatyana Gerachshenko, Trillium Blackmer, Eun-Ja Yoon, Cheryl Bartleson, Heidi E Hamm and Simon Alford
Nature Neuroscience 8, 597–605
(May 2005); doi:10.1038/nn1439
| Abstract | Full Text (HTML/PDF) |

news and views
Finding the G spot on fusion machinery
Jane Sullivan
Nature Neuroscience 8, 542–544
(May 2005); doi:10.1038/nn0505-542
| Full Text (HTML/PDF) |

review article
WNTS in the vertebrate nervous system: from patterning to neuronal connectivity
Lorenza Ciani and Patricia C. Salinas
Nature Reviews Neuroscience 6, 351–362
(May 2005); doi:10.1038/nrn1665
| Summary | Full Text (HTML / PDF) |

article
The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids
Jean-Michel Revest, Francesco Di Blasi, Pierre Kitchener, Françoise Rougé-Pont, Aline Desmedt, Marc Turiault, François Tronche and Pier Vincenzo Piazza
Nature Neuroscience 8, 664–672
(May 2005); doi:10.1038/nn1441
| Abstract | Full Text (HTML/PDF) |

review article
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome
Claudia Bagni and William T. Greenough
Nature Reviews Neuroscience 6, 376–387
(May 2005); doi:10.1038/nrn1667
| Summary | Full Text (HTML / PDF) |

review article
Rho kinase, a promising drug target for neurological disorders
Bernhard K. Mueller, Helmut Mack and Nicole Teusch
Nature Reviews Drug Discovery 4, 387–398
(May 2005); doi:10.1038/nrd1719
| Summary | Full Text (HTML / PDF) |

letters to nature
Regulation of axon growth in vivo by activity-based competition
Jackie Yuanyuan Hua, Matthew C. Smear, Herwig Baier and Stephen J. Smith
Nature 434, 1022–1026
(21 April 2005); doi:10.1038/nature03409
| First Paragraph | Full Text (HTML / PDF) |

news and views
Neurobiology: Sculpted by competition
Ole Petter Ottersen
Nature 434, 969
(21 April 2005); doi:10.1038/434969a
| Full Text (HTML / PDF) |

article
Drosophila N-cadherin mediates an attractive interaction between photoreceptor axons and their targets
Saurabh Prakash, Jason C Caldwell, Daniel F Eberl and Thomas R Clandinin
Nature Neuroscience 8, 443–450
(April 2005); doi:10.1038/nn1415
| Abstract | Full Text (HTML/PDF) |

news and views
Photoreceptor axons play hide and seek
Javier Morante and Claude Desplan
Nature Neuroscience 8, 401–402
(April 2005); doi:10.1038/nn0405-401
| Full Text (HTML/PDF) |

article
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses
Anthone W Dunah, Emily Hueske, Michael Wyszynski, Casper C Hoogenraad, Jacek Jaworski, Daniel T Pak, Alyson Simonetta, Guosong Liu and Morgan Sheng
Nature Neuroscience 8, 458–467
(April 2005); doi:10.1038/nn1416
| Abstract | Full Text (HTML/PDF) |

article
Protocadherin Celsr3 is crucial in axonal tract development
Fadel Tissir, Isabelle Bar, Yves Jossin and Andre M Goffinet
Nature Neuroscience 8, 451–457
(April 2005); doi:10.1038/nn1428
| Abstract | Full Text (HTML/PDF) |

review article
The role of calmodulin as a signal integrator for synaptic plasticity
Zhengui Xia and Daniel R. Storm
Nature Reviews Neuroscience 6, 267–276
(April 2005); doi:10.1038/nrn1647
| Summary | Full Text (HTML / PDF) |

brief communication
A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size
Jacquelyn Bond, Emma Roberts, Kelly Springell, Sophia Lizarraga, Sheila Scott, Julie Higgins, Daniel J Hampshire, Ewan E Morrison, Gabriella F Leal, Elias O Silva, Suzana M R Costa, Diana Baralle, Michela Raponi, Gulshan Karbani, Yasmin Rashid, Hussain Jafri, Christopher Bennett, Peter Corry, Christopher A Walsh and C Geoffrey Woods
Nature Genetics 37, 353–355
(April 2005); doi:10.1038/ng1539
| First Paragraph | Full Text (HTML/PDF) |

article
Sonic hedgehog guides commissural axons along the longitudinal axis of the spinal cord
Dimitris Bourikas, Vladimir Pekarik, Thomas Baeriswyl, Åsa Grunditz, Rejina Sadhu, Michele Nardó and Esther T Stoeckli
Nature Neuroscience 8, 297–304
(March 2005); doi:10.1038/nn1396
| Abstract | Full Text (HTML/PDF) |

review article
The floor plate: multiple cells, multiple signals
Marysia Placzek and James Briscoe
Nature Reviews Neuroscience 6, 230–240
(March 2005); doi:10.1038/nrn1628
| Summary | Full Text (HTML / PDF) |

article
Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression
Alexandre Méjat, Francis Ramond, Rhonda Bassel-Duby, Saadi Khochbin, Eric N Olson and Laurent Schaeffer
Nature Neuroscience 8, 313–321
(March 2005); doi:10.1038/nn1408
| Abstract | Full Text (HTML/PDF) |

review article
Molecular motors and mechanisms of directional transport in neurons
Nobutaka Hirokawa and Reiko Takemura
Nature Reviews Neuroscience 26, 201–214
(2005); doi:10.1038/nrn1624
| Summary | Full Text (HTML / PDF) |

letter
PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1
Takashi Nishimura, Tomoya Yamaguchi, Katsuhiro Kato, Masato Yoshizawa, Yo-ichi Nabeshima, Shigeo Ohno, Mikio Hoshino and Kozo Kaibuchi
Nature Cell Biology 7, 270–277
(March 2005); doi:10.1038/ncb1227
| First Paragraph | Full Text (HTML/PDF) |

news and views
Pars and polarity: taking control of Rac
Toby W. Hurd and Ben Margolis
Nature Cell Biology 7, 205–207
(March 2005); doi:10.1038/ncb0305-205
| Full Text (HTML/PDF) |

article
Soluble CPG15 expressed during early development rescues cortical progenitors from apoptosis
Ulrich Putz, Corey Harwell and Elly Nedivi
Nature Neuroscience 8, 322–331
(March 2005); doi:10.1038/nn1407
| Abstract | Full Text (HTML/PDF) |

review article
Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors
Mark Farrant and Zoltan Nusser
Nature Reviews Neuroscience 6, 215–229
(March 2005); doi:10.1038/nrn1625
| Summary | Full Text (HTML / PDF) |

letters to nature
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1
Sherif F. El-Khamisy, Gulam M. Saifi, Michael Weinfeld, Fredrik Johansson, Thomas Helleday, James R. Lupski and Keith W. Caldecott
Nature 434, 108–113
(03 March 2005); doi:10.1038/nature03314
| First Paragraph | Full Text (HTML / PDF) |

article
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis
Melanie Greter, Frank L Heppner, Maria P Lemos, Bernhard M Odermatt, Norbert Goebels, Terri Laufer, Randolph J Noelle and Burkhard Becher
Nature Medicine 11, 328–334
(March 2005); doi:10.1038/nm1197
| Abstract | Full Text (HTML/PDF) |

letter
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis
Eileen J McMahon, Samantha L Bailey, Carol Vanderlugt Castenada, Hanspeter Waldner and Stephen D Miller
Nature Medicine 11, 335–339
(March 2005); doi:10.1038/nm1202
| First Paragraph | Full Text (HTML/PDF) |

news and views
Multiple sclerosis: trapped in deadly glue
Michael Platten and Lawrence Steinman
Nature Medicine 11, 252–253
(March 2005); doi:10.1038/nm0305-252
| Full Text (HTML/PDF) |

review article
Expression and functions of neuronal gap junctions
Goran Söhl, Stephan Maxeiner and Klaus Willecke
Nature Reviews Neuroscience 6, 191–200
(March 2005); doi:10.1038/nrn1627
| Summary | Full Text (HTML / PDF) |

review article
Lipid regulation of the synaptic vesicle cycle
Jeffrey Rohrbough and Kendal Broadie
Nature Reviews Neuroscience 6, 139–150
(February 2005); doi:10.1038/nrn1608
| Summary | Full Text (HTML / PDF) |

article
Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation
Michael Piper, Saif Salih, Christine Weinl, Christine E Holt and William A Harris
Nature Neuroscience 8, 179–186
(February 2005); doi:10.1038/nn1380
| Abstract | Full Text (HTML/PDF) |

review article
The organization of recent and remote memories
Paul W. Frankland and Bruno Bontempi
Nature Reviews Neuroscience 6, 119–130
(February 2005); doi:10.1038/nrn1607
| Summary | Full Text (HTML / PDF) |

research article
Specification of motoneurons from human embryonic stem cells
Xue-Jun Li, Zhong-Wei Du, Ewa D Zarnowska, Matthew Pankratz, Lauren O Hansen, Robert A Pearce and Su-Chun Zhang
Nature Biotechnology 23, 215–221
(February 2005); doi:10.1038/nbt1063
| First Paragraph | Full Text (HTML/PDF) |

article
Activity-dependent liberation of synaptic neuropeptide vesicles
Dinara Shakiryanova, Arvonn Tully, Randall S Hewes, David L Deitcher and Edwin S Levitan
Nature Neuroscience 8, 173–178
(February 2005); doi:10.1038/nn1377
| Abstract | Full Text (HTML/PDF) |

article
Cyclic AMP controls BDNF-induced TrkB phosphorylation and dendritic spine formation in mature hippocampal neurons
Yuanyuan Ji, Petti T Pang, Linyin Feng and Bai Lu
Nature Neuroscience 8, 164–172
(February 2005); doi:10.1038/nn1381
| Abstract | Full Text (HTML/PDF) |

review article
Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
Chad J. Swanson, Mark Bures, Michael P. Johnson, Anni-Maija Linden, James A. Monn and Darryle D. Schoepp
Nature Reviews Drug Discovery 4, 131–144
(February 2005); doi:10.1038/nrd1630
| Summary | Full Text (HTML / PDF) |

article
Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo
Krystyna Keleman, Carlos Ribeiro and Barry J Dickson
Nature Neuroscience 8, 156–163
(February 2005); doi:10.1038/nn1388
| Abstract | Full Text (HTML/PDF) |

news and views
Comm-ing across the midline
Catherine E Krull
Nature Neuroscience 8, 131–132
(February 2005); doi:10.1038/nn0205-131
| Full Text (HTML/PDF) |

article
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
Shin-ichi Horike, Shutao Cai, Masaru Miyano, Jan-Fang Cheng and Terumi Kohwi-Shigematsu
Nature Genetics 37, 31–40
(January 2005); doi:10.1038/ng1491
| Abstract | Full Text (HTML/PDF) |

news and views
Synapsis or silence
John Schimenti
Nature Genetics 37, 11–13
(January 2005); doi:10.1038/ng0105-11
| Full Text (HTML/PDF) |

article
The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals
Robert O'Hagan, Martin Chalfie and Miriam B Goodman
Nature Neuroscience 8, 43–50
(January 2005); doi:10.1038/nn1362
| Abstract | Full Text (HTML/PDF) |

news and views
Metazoan mechanotransduction mystery finally solved
Diane Ronan and Peter Gillespie
Nature Neuroscience 8, 7–8
(January 2005); doi:10.1038/nn0105-7
| Full Text (HTML/PDF) |

brief communication
Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster
Ammon B Corl, Aylin R Rodan and Ulrike Heberlein
Nature Neuroscience 8, 18–19
(January 2005); doi:10.1038/nn1363
| First Paragraph | Full Text (HTML/PDF) |

article
Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development
Silvana B Rosso, Daniel Sussman, Anthony Wynshaw-Boris and Patricia C Salinas
Nature Neuroscience 8, 34–42
(January 2005); doi:10.1038/nn1374
| Abstract | Full Text (HTML/PDF) |

letters to nature
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Jeffrey D. Rothstein, Sarjubhai Patel, Melissa R. Regan, Christine Haenggeli, Yanhua H. Huang, Dwight E. Bergles, Lin Jin, Margaret Dykes Hoberg, Svetlana Vidensky, Dorothy S. Chung, Shuy Vang Toan, Lucie I. Bruijn, Zao-zhong Su, Pankaj Gupta and Paul B. Fisher
Nature 433, 73–77
(06 January 2005); doi:10.1038/nature03180
| First Paragraph | Full Text (HTML / PDF) |

review article
The neuropathogenesis of AIDS
Francisco González-Scarano and Julio Martín-García
Nature Reviews Immunology 5, 69–81
(January 2005); doi:10.1038/nri1527
| Summary | Full Text (HTML / PDF) |

review article
Modulation of neurodegeneration by molecular chaperones
Paul J. Muchowski and Jennifer L. Wacker
Nature Reviews Neuroscience 6, 11–22
(January 2005); doi:10.1038/nrn1587
| Summary | Full Text (HTML / PDF) |

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