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Research library: Neurobiology

2006: December | November | October | September | August | July | June | May | April | March | February | January

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letter
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity
Rongsheng Jin, Andreas Rummel, Thomas Binz and Axel T. Brunger
Nature 444, 1092–1095
(21 December 2006); doi:10.1038/nature05387
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letter
Structural basis of cell surface receptor recognition by botulinum neurotoxin B
Qing Chai, Joseph W. Arndt, Min Dong, William H. Tepp, Eric A. Johnson, Edwin R. Chapman and Raymond C. Stevens
Nature 444, 1096–1100
(21 December 2006); doi:10.1038/nature05411
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letter
Bace1 modulates myelination in the central and peripheral nervous system
Xiangyou Hu, Caitlin W Hicks, Wanxia He, Philip Wong, Wendy B Macklin, Bruce D Trapp & Riqiang Yan
Nature Neuroscience 9, 1520–1525
(December 2006); doi:10.1038/nn1797
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review
High-conductance potassium channels of the SLO family
Lawrence Salkoff, Alice Butler, Gonzalo Ferreira, Celia Santi and Aguan Wei
Nature Reviews Neuroscience 7, 1520–1525
(December 2006); doi:10.1038/nrn1992
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article
An SCN9A channelopathy causes congenital inability to experience pain
James J. Cox, Frank Reimann, Adeline K. Nicholas, Gemma Thornton, Emma Roberts, Kelly Springell, Gulshan Karbani, Hussain Jafri, Jovaria Mannan, Yasmin Raashid, Lihadh Al-Gazali, Henan Hamamy, Enza Maria Valente, Shaun Gorman, Richard Williams, Duncan P. McHale, John N. Wood, Fiona M. Gribble and C. Geoffrey Woods
Nature 444, 894–898
(14 December 2006); doi:10.1038/nature05413
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news and views
Neurobiology: A channel sets the gain on pain
Stephen G. Waxman
Nature 444, 831–832
(14 December 2006); doi:10.1038/444831a
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article
A diacylglycerol kinase modulates long-term thermotactic behavioral plasticity in C. elegans
David Biron, Mayumi Shibuya, Christopher Gabel, Sara M Wasserman, Damon A Clark, Adam Brown, Piali Sengupta & Aravinthan D T Samuel
Nature Neuroscience 9, 1499–1505
(December 2006); doi:10.1038/nn1796
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article
Dynorphin A activates bradykinin receptors to maintain neuropathic pain
Josephine Lai, Miaw-Chyi Luo, Qingmin Chen, Shouwu Ma, Luis R Gardell, Michael H Ossipov & Frank Porreca
Nature Neuroscience 9, 1534–1540
(December 2006); doi:10.1038/nn1804
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letter
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells
S. G. M. Piccirillo, B. A. Reynolds, N. Zanetti, G. Lamorte, E. Binda, G. Broggi, H. Brem, A. Olivi, F. Dimeco and A. L. Vescovi
Nature 444, 761–765
(7 December 2006); doi:10.1038/nature05349
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article
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
Sharon E Haynes, Gunther Hollopeter, Guang Yang, Dana Kurpius, Michael E Dailey, Wen-Biao Gan & David Julius
Nature Neuroscience 9, 1512–1519
(December 2006); doi:10.1038/nn1805
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news and views
Triggering the brain's pathology sensor
Helmut Kettenmann
Nature Neuroscience 9, 1463–1464
(December 2006); doi:10.1038/nn1206-1463
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article
SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS
Ya Dai, Hidenori Taru, Scott L Deken, Brock Grill, Brian Ackley, Michael L Nonet & Yishi Jin
Nature Neuroscience 9, 1479–1487
(December 2006); doi:10.1038/nn1808
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review
Axonal conduction and injury in multiple sclerosis: the role of sodium channels
Stephen G. Waxman
Nature Reviews Neuroscience 7, 932–941
(December 2006); doi:10.1038/nrn2023
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article
Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
Neeta S Roy, Carine Cleren, Shashi K Singh, Lichuan Yang, M Flint Beal & Steven A Goldman
Nature Medicine 12, 1259–1268
(November 2006); doi:10.1038/nm1495
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article
Local potassium signaling couples neuronal activity to vasodilation in the brain
Jason S Carroll, Clifford A Meyer, Jun Song, Wei Li, Timothy R Geistlinger, Jérôme Eeckhoute, Alexander S Brodsky, Erika Krasnickas Keeton, Kirsten C Fertuck, Giles F Hall, Qianben Wang, Stefan Bekiranov, Victor Sementchenko, Edward A Fox, Pamela A Silver, Thomas R Gingeras, X Shirley Liu & Myles Brown
Nature Neuroscience 9, 1397–1403
(November 2006); doi:10.1038/nn1779
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article
IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
P Hande Özdinler & Jeffrey D Macklis
Nature Neuroscience 9, 1371–1381
(November 2006); doi:10.1038/nn1789
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letter
Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites
Alastair M. Hosie, Megan E. Wilkins, Helena M. A. da Silva and Trevor G. Smart
Nature 444, 486–489
(23 November 2006); doi:10.1038/nature05324
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letter
Boc is a receptor for sonic hedgehog in the guidance of commissural axons
Ami Okada , Frédéric Charron , Steves Morin, David S. Shin, Karen Wong, Pierre J. Fabre, Marc Tessier-Lavigne and Susan K. McConnell
Nature 444, 369–373
(16 November 2006); doi:10.1038/nature05246
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article
Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage
Tong Cheng, Anthony L Petraglia, Zhang Li, Meenakshisundaram Thiyagarajan, Zhihui Zhong, Zhenhua Wu, Dong Liu, Sanjay B Maggirwar, Rashid Deane, José A Fernández, Barbra LaRue, John H Griffin, Michael Chopp & Berislav V Zlokovic
Nature Medicine 12, 1278–1285
(November 2006); doi:10.1038/nm1498
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review
Reelin, lipoprotein receptors and synaptic plasticity
Joachim Herz and Ying Chen
Nature Reviews Neuroscience 7, 850–859
(November 2006); doi:10.1038/nrn2009
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review
Regulation of cell fate in the sensory epithelia of the inner ear
Matthew W. Kelley
Nature Reviews Neuroscience 7, 837–849
(November 2006); doi:10.1038/nrn1987
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letter
Retinal repair by transplantation of photoreceptor precursors
R. E. MacLaren , R. A. Pearson, A. MacNeil, R. H. Douglas, T. E. Salt, M. Akimoto, A. Swaroop, J. C. Sowden and R. R. Ali
Nature 444, 203–207
(09 November 2006); doi:10.1038/nature05161
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news and views
Neurobiology: Right timing for retina repair
Thomas A. Reh
Nature 444, 156–157
(09 November 2006); doi:10.1038/444156a
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letter
Spider toxins activate the capsaicin receptor to produce inflammatory pain
Jan Siemens, Sharleen Zhou, Rebecca Piskorowski, Tetsuro Nikai, Ellen A. Lumpkin, Allan I. Basbaum, David King and David Julius
Nature 444, 208–212
(09 November 2006); doi:10.1038/nature05285
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news and views
Physiology: Channelled pain
Lesley Anson
Nature 444, 156
(09 November 2006); doi:10.1038/444156b
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letter
Two modes of fusion pore opening revealed by cell-attached recordings at a synapse
Liming He, Xin-Sheng Wu, Raja Mohan and Ling-Gang Wu
Nature 444, 102–105
(02 November 2006); doi:10.1038/nature05250
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article
Activation of a presynaptic glutamate transporter regulates synaptic transmission through electrical signaling
Margaret Lin Veruki, Svein Harald Mørkve & Espen Hartveit
Nature Neuroscience 11, 1388–1396
(November 2006); doi:10.1038/nn1793
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news and views
Long-distance signaling via presynaptic glutamate transporters
Jacques I Wadiche & Henrique von Gersdorff
Nature Neuroscience 11, 1352–1353
(November 2006); doi:10.1038/nn1106-1352
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article
Asymmetrical beta-actin mRNA translation in growth cones mediates attractive turning to netrin-1
Kin-Mei Leung, Francisca PG van Horck, Andrew C Lin, Rachel Allison, Nancy Standart & Christine E Holt
Nature Neuroscience 9, 1247–1256
(September 2006); doi:10.1038/nn1775
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article
An essential role for β-actin mRNA localization and translation in Ca2+-dependent growth cone guidance
Jiaqi Yao, Yukio Sasaki, Zhexing Wen, Gary J Bassell & James Q Zheng
Nature Neuroscience 9, 1265–1273
(September 2006); doi:10.1038/nn1773
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news and views
Turning by asymmetric actin
Guo-li Ming
Nature Neuroscience 9, 1201–1203
(September 2006); doi:10.1038/nn1006-1201
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article
Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones
Karen Y Wu, Jonathan H Zippin, David R Huron, Margarita Kamenetsky, Ulrich Hengst, Jochen Buck, Lonny R Levin & Samie R Jaffrey
Nature Neuroscience 9, 1257–1264
(September 2006); doi:10.1038/nn1767
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article
Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling
Víctor Borrell & Oscar Marín
Nature Neuroscience 9, 1284–1293
(September 2006); doi:10.1038/nn1764
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article
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport
Sara K Custer, Gwenn A Garden, Nishi Gill, Udo Rueb, Randell T Libby, Christian Schultz, Stephan J Guyenet, Thomas Deller, Lesnick E Westrum, Bryce L Sopher & Albert R La Spada
Nature Neuroscience 9, 1302–1311
(September 2006); doi:10.1038/nn1750
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news and views
Intercellular miscommunication in polyglutamine pathogenesis
Christopher A Ross & Don W Cleveland
Nature Neuroscience 9, 1205–1206
(September 2006); doi:10.1038/nn1006-1205
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review
Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development
Marc Fuccillo, Alexandra L. Joyner and Gord Fishell
Nature Reviews Neuroscience 9, 772–783
(September 2006); doi:10.1038/nrn1990
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review
Novel pharmacological targets for the treatment of Parkinson's disease
Anthony H. V. Schapira , Erwan Bezard, Jonathan Brotchie, Frédéric Calon, Graham L. Collingridge, Borris Ferger, Bastian Hengerer, Etienne Hirsch , Peter Jenner, Nicolas Le Novère, José A. Obeso, Michael A. Schwarzschild, Umberto Spampinato and Giora Davidai
Nature Reviews Drug Discovery 5, 845–854
(October 2006); doi:10.1038/nrd2087
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letter
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
Julia Skokowa, Gunnar Cario, Murat Uenalan, Axel Schambach, Manuela Germeshausen, Karin Battmer, Cornelia Zeidler, Ulrich Lehmann, Matthias Eder, Christopher Baum, Rudolf Grosschedl, Martin Stanulla, Michaela Scherr & Karl Welte
Nature Medicine 12, 1191–1197
(2006); doi:10.1038/nm1484
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article
Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding
Estuardo Robles & Timothy M Gomez
Nature Neurology 9, 1274–1283
(2006); doi:10.1038/nn1762
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news and views
Signalling platforms that modulate the inflammatory response: new targets for drug development
Christopher. A. McCulloch, Gregory P. Downey and Hani El-Gabalawy
Nature Reviews Drug Discovery 5, 864–876
(2006); doi:10.1038/nrd2109
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letter
Fast neurotransmitter release triggered by Ca influx through AMPA-type glutamate receptors
Andrés E. Chávez, Joshua H. Singer and Jeffrey S. Diamond
Nature 443, 705–708
(12 October 2006); doi:10.1038/nature05123
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letter
Bidirectional control of CNS capillary diameter by pericytes
Claire M. Peppiatt, Clare Howarth, Peter Mobbs and David Attwell
Nature 443, 700–704
(12 October 2006); doi:10.1038/nature05193
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brief communication
Local caspase activity directs engulfment of dendrites during pruning
Darren W Williams, Shu Kondo, Agnieszka Krzyzanowska, Yasushi Hiromi & James W Truman
Nature Neuroscience 9, 1234–1236
(2006); doi:10.1038/nn1774
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article
NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation
Seho Kim, Alain Burette, Hye Sun Chung, Seok-Kyu Kwon, Jooyeon Woo, Hyun Woo Lee, Karam Kim, Hyun Kim, Richard J Weinberg & Eunjoon Kim
Nature Neuroscience 9, 1294–1301
(October 2006); doi:10.1038/nn1763
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news and views
Hooking up new synapses
Thomas Biederer
Nature Neuroscience 9, 1203–1204
(October 2006); doi:10.1038/nn1006-1203
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perspective
Channelrhodopsin-2 and optical control of excitable cells
Feng Zhang, Li-Ping Wang, Edward S Boyden & Karl Deisseroth
Nature Methods 5, 785–792
(October 2006); doi:10.1038/nmeth936
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Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
Anna V. Molofsky, Shalom G. Slutsky, Nancy M. Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E. Sharpless and Sean J. Morrison
Nature 443, 448–452
(28 September 2006); doi:10.1038/nature05091
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letter
p16INK4a induces an age-dependent decline in islet regenerative potential
Janakiraman Krishnamurthy, Matthew R. Ramsey, Keith L. Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir and Norman E. Sharpless
Nature 443, 453–457
(28 September 2006); doi:10.1038/nature05092
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news and views
Ageing: Balancing regeneration and cancer
Christian M Beausejour and Judith Campisi
Nature AOP (27 September 2006); doi:10.1038/nature05221
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article
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface
Silvia Cappello, Alessio Attardo, Xunwei Wu, Takuji Iwasato, Shigeyoshi Itohara, Michaela Wilsch-Bräuninger, Hanna M Eilken, Michael A Rieger, Timm T Schroeder, Wieland B Huttner, Cord Brakebusch & Magdalena Götz
Nature Neuroscience 9, 1099–1107
(September 2006); doi:10.1038/nn1744
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article
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype
Catherine Heurteaux, Guillaume Lucas, Nicolas Guy, Malika El Yacoubi, Susanne Thümmler, Xiao-Dong Peng, Florence Noble, Nicolas Blondeau, Catherine Widmann, Marc Borsotto, Gabriella Gobbi, Jean-Marie Vaugeois, Guy Debonnel & Michel Lazdunski
Nature Neuroscience 9, 1134–1141
(2006); doi:10.1038/nn1749
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news and views
TREKing toward new antidepressants
Joshua A Gordon & Rene Hen
Nature Neuroscience 9, 1081–1083
(2006); doi:10.1038/nn0906-1081
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letter
The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance
Kazuo Emoto, Jay Z. Parrish, Lily Yeh Jan and Yuh-Nung Jan
Nature 443, 210–213
(14 September 2006); doi:10.1038/nature05090
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article
Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice
Geert van Loo, Rossana De Lorenzi, Hauke Schmidt, Marion Huth, Alexander Mildner, Marc Schmidt-Supprian, Hans Lassmann, Marco R Prinz and Manolis Pasparakis
Nature Immunology 7, 954–961
(2006); doi:10.1038/ni1372
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news and views
At once harmful and beneficial: the dual properties of NF-κB
Sawsan Youssef & Lawrence Steinman
Nature Immunology 7, 901–902
(2006); doi:10.1038/ni0906-901
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article
Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration
Jeong Woong Lee, Kirk Beebe, Leslie A. Nangle, Jaeseon Jang, Chantal M. Longo-Guess, Susan A. Cook, Muriel T. Davisson, John P. Sundberg, Paul Schimmel and Susan L. Ackerman
Nature 443, 50–55
(7 September 2006); doi:10.1038/nature05096
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news and views
Molecular biology: Sticky end in protein synthesis
Hervé Roy and Michael Ibba
Nature 443, 41–42
(7 September 2006); doi:10.1038/nature05002
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article
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
Jason S Stumhofer, Arian Laurence, Emma H Wilson, Elaine Huang, Cristina M Tato, Leanne M Johnson, Alejandro V Villarino, Qiulong Huang, Akihiko Yoshimura, David Sehy, Christiaan J M Saris, John J O'Shea, Lothar Hennighausen, Matthias Ernst & Christopher A Hunter
Nature Immunology 7, 937–945
(13 August 2006); doi:10.1038/ni1376
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article
C-terminal modulator controls Ca2+-dependent gating of Cav1.4 L-type Ca2+ channels
Anamika Singh, Daniel Hamedinger, Jean-Charles Hoda, Mathias Gebhart, Alexandra Koschak, Christoph Romanin & Jörg Striessnig
Nature Neuroscience 9, 1108–1116
(September 2006); doi:10.1038/nn1751
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letter
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
Matt Baker, Ian R. Mackenzie, Stuart M. Pickering-Brown , Jennifer Gass, Rosa Rademakers, Caroline Lindholm, Julie Snowden, Jennifer Adamson, A. Dessa Sadovnick, Sara Rollinson, Ashley Cannon, Emily Dwosh, David Neary, Stacey Melquist, Anna Richardson, Dennis Dickson, Zdenek Berger, Jason Eriksen, Todd Robinson, Cynthia Zehr, Chad A. Dickey, Richard Crook, Eileen McGowan, David Mann, Bradley Boeve, Howard Feldman and Mike Hutton
Nature 442, 916–919
(24 August 2006); doi:10.1038/nature05016
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letter
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
Marc Cruts , Ilse Gijselinck , Julie van der Zee , Sebastiaan Engelborghs , Hans Wils , Daniel Pirici , Rosa Rademakers , Rik Vandenberghe, Bart Dermaut, Jean-Jacques Martin, Cornelia van Duijn, Karin Peeters , Raf Sciot, Patrick Santens, Tim De Pooter , Maria Mattheijssens , Marleen Van den Broeck , Ivy Cuijt , Krist'l Vennekens , Peter P. De Deyn , Samir Kumar-Singh and Christine Van Broeckhoven
Nature 442, 920–924
(24 August 2006); doi:10.1038/nature05017
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letter
NMDA-receptor-mediated, cell-specific integration of new neurons in adult dentate gyrus
Ayumu Tashiro, Vladislav M. Sandler, Nicolas Toni, Chunmei Zhao and Fred H. Gage
Nature 442, 929–933
(24 August 2006); doi:10.1038/nature05028
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letter
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
Lara Fallon, Catherine M.L. Bélanger, Amadou T. Corera, Maria Kontogiannea, Elsa Regan-Klapisz, France Moreau, Jarno Voortman, Michael Haber, Geneviève Rouleau, Thorhildur Thorarinsdottir, Alexis Brice, Paul M.P. van Bergen en Henegouwen & Edward A. Fon
Nature Cell Biology 8, 834–842
(August 2006); doi:10.1038/ncb1441
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news and views
EGFR trafficking: parkin' in a jam
Koraljka Husnjak & Ivan Dikic
Nature Cell Biology 8, 787–788
(August 2006); doi:10.1038/ncb0806-787
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article
BDNF-mediated neurotransmission relies upon a myosin VI motor complex
Hiroko Yano, Ipe Ninan, Hong Zhang, Teresa A Milner, Ottavio Arancio & Moses V Chao
Nature Neuroscience 12, 1009–1018
(August 2006); doi:10.1038/nn1730
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letter
Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology
Yong Kim, Jee Young Sung, Ilaria Ceglia, Ko-Woon Lee, Jung-Hyuck Ahn, Jonathan M. Halford, Amie M. Kim, Seung P. Kwak, Jong Bae Park, Sung Ho Ryu, Annette Schenck, Barbara Bardoni, John D. Scott, Angus C. Nairn and Paul Greengard
Nature 442, 814–817
(10 August 2006); doi:10.1038/nature04976
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article
Vesicular proteins exocytosed and subsequently retrieved by compensatory endocytosis are nonidentical
Martin Wienisch & Jurgen Klingauf
Nature Neurosceince 9, 1019–1027
(10 August 2006); doi:10.1038/nn1739
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article
A second class of chemosensory receptors in the olfactory epithelium
Stephen D. Liberles and Linda B. Buck
Nature 442, 645–650
(10 August 2006); doi:10.1038/nature05066
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news and views
Neuroscience: An extra dimension to olfaction
John Ngai
Nature 442, 637–638
(10 August 2006); doi:10.1038/nature05001
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article
G(o) signaling is required for Drosophila associative learning
Jacob Ferris, Hong Ge, Lingzhi Liu & Gregg Roman
Nature Review Genetics 9, 1036–1040
(August 2006); doi:10.1038/nn1738
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brief communication
UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1
Megan E Williams, Xiaowei Lu, William L McKenna, Raesha Washington, Adam Boyette, Phyllis Strickland, Allison Dillon, Zaven Kaprielian, Marc Tessier-Lavigne & Lindsay Hinck
Nature Neuroscience 9, 996–998
(August 2006); doi:10.1038/nn1736
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letter
Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth
Anna Lasorella , Judith Stegmüller, Daniele Guardavaccaro, Guangchao Liu, Maria S. Carro, Gerson Rothschild, Luis de la Torre-Ubieta, Michele Pagano, Azad Bonni and Antonio Iavarone
Nature 442, 471–474
(27 July 2006); doi:10.1038/nature04895
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news and views
Developmental neurobiology: A destructive switch for neurons
Peter K. Jackson
Nature 442, 365–366
(27 July 2006); doi:10.1038/442365a
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article
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
Gerardo Morfini, Gustavo Pigino, Györgyi Szebenyi, Yimei You, Sarah Pollema & Scott T Brady
Nature Neuroscience 9, 907–916
(June 2006); doi:10.1038/nn1717
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review
Variability, compensation and homeostasis in neuron and network function
Eve Marder and Jean-Marc Goaillard
Nature Neuroscience 7, 563–574
(July 2006); doi:10.1038/nrn1949
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letter
Altered neuregulin 1-erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia
Chang-Gyu Hahn, Hoau-Yan Wang, Dan-Sung Cho, Konrad Talbot, Raquel E Gur, Wade H Berrettini, Kalindi Bakshi, Joshua Kamins, Karin E Borgmann-Winter, Steven J Siegel, Robert J Gallop & Steven E Arnold
Nature Medicine 442, 824–828
(July 2006); doi:10.1038/nm1418
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news and views
Schizophrenia: signals from the other side
Gerald D Fischbach
Nature Medicine 7, 734–1735
(July 2006); doi:10.1038/nm0706-734
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article
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
Min-Seon Kim, Youngmi K Pak, Pil-Geum Jang, Cherl Namkoong, Yon-Sik Choi, Jong-Chul Won, Kyung-Sup Kim, Seung-Whan Kim, Hyo-Soo Kim, Joong-Yeol Park, Young-Bum Kim, Ki-Up Lee
Nature Neuroscience 49, 901–906
(July 2006); doi:10.1038/nn1731
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review
The distribution and targeting of neuronal voltage-gated ion channels
Helen C. Lai and Lily Y. Jan
Nature Reviews Neuroscience 7, 548–562
(July 2006); doi:10.1038/nrn1938
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review
The neurobiology of itch
Akihiko Ikoma, Martin Steinhoff, Sonja Ständer, Gil Yosipovitch and Martin Schmelz
Nature Reviews Neuroscience 7, 535–547
(25 June 2006); doi:10.1038/nrn1950
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article
AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
Vikram R Rao, Sean A Pintchovski, Jeannie Chin, Carol L Peebles, Siddhartha Mitra & Steven Finkbeiner
Nature Neuroscience 7, 887–895
(July 2006); doi:10.1038/nn1708
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letter
Activity-dependent dynamics and sequestration of proteasomes in dendritic spines
Baris Bingol and Erin M. Schuman
Nature 441, 1144–1148
(29 June 2006); doi:10.1038/nature04769
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letter
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park , Sung Bae Lee , Sungkyu Lee, Yongsung Kim, Saera Song, Sunhong Kim, Eunkyung Bae, Jaeseob Kim, Minho Shong, Jin-Man Kim and Jongkyeong Chung
Nature 441, 1157–1161
(29 June 2006); doi:10.1038/nature04788
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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark, Mark W. Dodson, Changan Jiang, Joseph H. Cao, Jun R. Huh, Jae Hong Seol, Soon Ji Yoo, Bruce A. Hay and Ming Guo
Nature 441, 1162–1166
(29 June 2006); doi:10.1038/nature04779
| First Paragraph | Full Text (HTML / PDF) |

news and views
Neurodegenerative disease: Pink, parkin and the brain
Leo Pallanck and J. Timothy Greenamyre
Nature 441, 1058
(29 June 2006); doi:10.1038/4411058a
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review article
Brain tumour stem cells
Angelo L. Vescovi, Rossella Galli and Brent A. Reynolds
Nature Reviews Cancer 6, 425–436
(June 2006); doi:10.1038/nrc1889
| Summary | Full Text (HTML / PDF) |

article
Midline radial glia translocation and corpus callosum formation require FGF signaling
Karen Müller Smith, Yasushi Ohkubo, Maria Elisabetta Maragnoli, Mladen-Roko Ras caronin, Michael L Schwartz, Nenad S caronestan & Flora M Vaccarino
Nature Neuroscience 9, 787 - 797
(June 2006); doi:10.1038/nn1705
| Summary | Full Text (HTML / PDF) |

review article
Purinergic signalling in neuron-glia interactions
R. Douglas Fields and Geoffrey Burnstock
Nature Reviews Neuroscience 7, 423–436
(June 2006); doi:10.1038/nrn1928
| Summary | Full Text (HTML / PDF) |

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Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain
Anke Tappe, Matthias Klugmann, Ceng Luo, David Hirlinger, Nitin Agarwal, Justus Benrath, Markus U Ehrengruber, Matthew J During & Rohini Kuner
Nature Medicine 12, 677 - 681
(June 2006); doi:10.1038/nm1406
| Summary | Full Text (HTML / PDF) |

article
Synapse-specific plasticity and compartmentalized signaling in cerebellar stellate cells
Markus Huber-Lang, J Vidya Sarma, Firas S Zetoune, Daniel Rittirsch, Thomas A Neff, Stephanie R McGuire, John D Lambris, Roscoe L Warner, Michael A Flierl, Laszlo M Hoesel, Florian Gebhard, John G Younger, Scott M Drouin, Rick A Wetsel & Peter A Ward
Nature Neuroscience 9, 798 - 806
(June 2006); doi:10.1038/nn1698
| Summary | Full Text (HTML / PDF) |

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Biochemical confinements without walls in aspiny neurons
Pablo E Castillo & Kamran Khodakhah
Nature Neuroscience 9, 719 - 720
(June 2006); doi:10.1038/nn0606-719
| Summary | Full Text (HTML / PDF) |

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Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu, Satoshi Waguri, Tomoki Chiba, Shigeo Murata, Jun-ichi Iwata, Isei Tanida, Takashi Ueno, Masato Koike, Yasuo Uchiyama, Eiki Kominami and Keiji Tanaka
Nature 441, 880–884
(15 June 2006); doi:10.1038/nature04723
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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara, Kenji Nakamura, Makoto Matsui, Akitsugu Yamamoto, Yohko Nakahara, Rika Suzuki-Migishima, Minesuke Yokoyama, Kenji Mishima, Ichiro Saito, Hideyuki Okano and Noboru Mizushima
Nature 441, 885–889
(15 June 2006); doi:10.1038/nature04724
| First Paragraph | Full Text (HTML / PDF) |

news and views
Neurodegeneration: Good riddance to bad rubbish
Daniel J. Klionsky
Nature 441, 819–820
(15 June 2006); doi:10.1038/441819a
| Full Text (HTML / PDF) |

brief communication
Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke
Thiruma V Arumugam, Sic L Chan, Dong-Gyu Jo, Gokhan Yilmaz, Sung-Chun Tang, Aiwu Cheng, Marc Gleichmann, Eitan Okun, Vishwa D Dixit, Srinivasulu Chigurupati, Mohamed R Mughal, Xin Ouyang, Lucio Miele, Tim Magnus, Suresh Poosala, D Neil Granger & Mark P Mattson
Nature Medicine 12, 621–623
(June 2006); doi:10.1038/nm1403
| First Paragraph | Full Text (HTML / PDF) |

article
Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells
Yuqin Yin, Michael T Henzl, Barbara Lorber, Toru Nakazawa, Tommy T Thomas, Fan Jiang, Robert Langer & Larry I Benowitz
Nature Neuroscience 9, 843–852
(June 2006); doi:10.1038/nn1701
| First Paragraph | Full Text (HTML / PDF) |

news and views
How inflammation promotes regeneration
Marie T Filbin
Nature Neuroscience 9, 715–717
(June 2006); doi:10.1038/nn0606-715
| First Paragraph | Full Text (HTML / PDF) |

article
Eph receptors are negatively controlled by protein tyrosine phosphatase receptor type O
Takafumi Shintani, Masaru Ihara, Hiraki Sakuta, Hiroo Takahashi, Ikuko Watakabe and Masaharu Noda
Nature Neuroscience 9, 761–769
(08 June 2006); doi:10.1038/nn1697
| First Paragraph | Full Text (HTML / PDF) |

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Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential
Yousheng Shu, Andrea Hasenstaub, Alvaro Duque, Yuguo Yu and David A. McCormick
Nature 441, 761–765
(08 June 2006); doi:10.1038/nature04720
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news and views
Neurobiology: Extending influence
Eve Marder
Nature 441, 702–703
(08 June 2006); doi:10.1038/441702a
| Full Text (HTML / PDF) |

article
Syndapin I is the phosphorylation-regulated dynamin I partner in synaptic vesicle endocytosis
Victor Anggono, Karen J Smillie, Mark E Graham, Valentina A Valova, Michael A Cousin & Phillip J Robinson
Nature Neuroscience 9, 752–760
(June 2006); doi:10.1038/nn1695
| Summary | Full Text (HTML / PDF) |

article
Astrocytic Ca2+ signaling evoked by sensory stimulation in vivo
Xiaohai Wang, Nanhong Lou, Qiwu Xu, Guo-Feng Tian, Wei Guo Peng, Xiaoning Han, Jian Kang, Takahiro Takano & Maiken Nedergaard
Nature Neuroscience 9, 816–823
(June 2006); doi:10.1038/nn1703
| Summary | Full Text (HTML / PDF) |

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S-Nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
Takashi Uehara, Tomohiro Nakamura, Dongdong Yao, Zhong-Qing Shi, Zezong Gu, Yuliang Ma, Eliezer Masliah, Yasuyuki Nomura and Stuart A. Lipton
Nature 441, 513–517
(May 2006); doi:10.1038/nature04782
| First Paragraph | Full Text (HTML / PDF) |

article
Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex
Daniela Tropea, Gabriel Kreiman, Alvin Lyckman, Sayan Mukherjee, Hongbo Yu, Sam Horng & Mriganka Sur
Nature Neuroscience 9, 660–668
(May 2006); doi:10.1038/nn1689
| Summary | Full Text (HTML / PDF) |

article
Clearing obsolete NMDA receptors
Annette Markus
Nature Neuroscience 9, 598
(May 2006); doi:10.1038/nn0506-598
| Summary | Full Text (HTML / PDF) |

letter
Specification of the neural crest occurs during gastrulation and requires Pax7
Martín L. Basch, Marianne Bronner–Fraser and Martín I. García–Castro
Nature 441, 218–222
(11 May 2006); doi:10.1038/nature04684
| First Paragraph | Full Text (HTML / PDF) |

brief communication
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock, Robert W Taylor & Douglass M Turnbull
Nature Genetics 38, 515–517
(May 2006); doi:10.1038/ng1769
| Full Text (HTML / PDF) |

brief communication
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
Yevgenya Kraytsberg, Elena Kudryavtseva, Ann C McKee, Changiz Geula, Neil W Kowall & Konstantin Khrapko
Nature Genetics 38, 518–520
(May 2006); doi:10.1038/ng1778
| Full Text (HTML / PDF) |

news and views
mtDNA clock runs out for dopaminergic neurons
Giovanni Manfredi
Nature Genetics 38, 507–508
(May 2006); doi:10.1038/ng0506–507
| Full Text (HTML / PDF) |

article
Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane
Guillermo A Yudowski, Manojkumar A Puthenveedu & Mark von Zastrow
Nature Neuroscience 9, 622–627
(May 2006); doi:10.1038/nn1679
| Summary | Full Text (HTML / PDF) |

brief communication
Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation
Karen Plant, Kenneth A Pelkey, Zuner A Bortolotto, Daiju Morita, Akira Terashima, Chris J McBain, Graham L Collingridge & John T R Isaac
Nature Neuroscience 9, 602–604
(May 2006) | doi:10.1038/nn1678
| First Paragraph | Full Text (HTML / PDF) |

news and views
LTP: AMPA receptors trading places
Julie A Kauer & Robert C Malenka
Nature Neuroscience 9, 593–594
(May 2006) | doi:10.1038/nn0506-593
| First Paragraph | Full Text (HTML / PDF) |

letter
TMP21 is a presenilin complex component that modulates γ-secretase but not ε-secretase activity
Fusheng Chen, Hiroshi Hasegawa , Gerold Schmitt-Ulms, Toshitaka Kawarai, Christopher Bohm, Taiichi Katayama, Yongjun Gu, Nobuo Sanjo, Michael Glista, Ekaterina Rogaeva, Yosuke Wakutani, Raphaëlle Pardossi-Piquard, Xueying Ruan, Anurag Tandon, FrÈdéric Checler, Philippe Marambaud, Kirk Hansen, David Westaway, Peter St George-Hyslop and Paul Fraser
Nature 440, 1208–1212
(27 April 2006); doi:10.1038/nature04667
| First Paragraph | Full Text (HTML / PDF) |

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Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes
Michael F Waters, Natali A Minassian, Giovanni Stevanin, Karla P Figueroa, John P A Bannister, Dagmar Nolte, Allan F Mock, Virgilio Gerald H Evidente, Dominic B Fee, Ulrich Müller, Alexandra Dürr, Alexis Brice, Diane M Papazian & Stefan M Pulst
Nature Genetics 38, 447–451
(April 2006); doi:10.1038/ng1758
| Summary | Full Text (HTML / PDF) |

review article
The therapeutic potential of monoamine oxidase inhibitors
Moussa B. H. Youdim, Dale Edmondson and Keith F. Tipton
Nature Reviews Neuroscience 7, 295–309
(April 2006); doi:10.1038/nrn1883
| Summary | Full Text (HTML / PDF) |

letter
Synaptic scaling mediated by glial TNF-α
David Stellwagen and Robert C. Malenka
Nature 440, 1054–1059
(20 April 2006); doi:10.1038/nature04671
| First Paragraph | Full Text (HTML / PDF) |

article
UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation
Carolyn E Adler, Richard D Fetter & Cornelia I Bargmann
Nature Neuroscience 9, 511 - 518
(April 2006); doi:10.1038/nn1666
| Summary | Full Text (HTML / PDF) |

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STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis
Katrin I. Willig, Silvio O. Rizzoli, Volker Westphal, Reinhard Jahn and Stefan W. Hell
Nature 440, 935–939
(13 April 2006); doi:10.1038/nature04592
| First Paragraph | Full Text (HTML / PDF) |

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Biological imaging: The diffraction barrier broken
Garth J. Simpson
Nature 440, 879–880
(13 April 2006); doi:10.1038/440879a
| Full Text (HTML / PDF) |

letter
Role of matrix metalloproteinases in delayed cortical responses after stroke
Bing-Qiao Zhao, Sophia Wang, Hahn-Young Kim, Hannah Storrie, Bruce R Rosen, David J Mooney, Xiaoying Wang & Eng H Lo
Nature Medicine 12, 441–445
(April 2006); doi:10.1038/nm1387
| First Paragraph | Full Text (HTML / PDF) |

article
Protein kinase A regulates calcium permeability of NMDA receptors
V Arvydas Skeberdis, Vivien Chevaleyre, C Geoffrey Lau, Jesse H Goldberg, Diana L Pettit, Sylvia O Suadicani, Ying Lin, Michael V L Bennett, Rafael Yuste, Pablo E Castillo & R Suzanne Zukin
Nature Neuroscience 9, 501–510
(April 2006); doi:10.1038/nn1664
| First Paragraph | Full Text (HTML / PDF) |

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A C. elegans stretch receptor neuron revealed by a mechanosensitive TRP channel homologue
Wei Li, Zhaoyang Feng, Paul W. Sternberg and X. Z. Shawn Xu
Nature 440, 684–687
(30 March 2006); doi:10.1038/nature04538
| First Paragraph | Full Text (HTML / PDF) |

article
Silencing of EphA3 through a cis interaction with ephrinA5
Ricardo F Carvalho, Martin Beutler, Katharine J M Marler, Bernd Knöll, Elena Becker-Barroso, R Heintzmann, Tony Ng & Uwe Drescher
Nature Neuroscience 9, 322–330
(March 2006); doi:10.1038/nn1655
| Summary | Full Text (HTML / PDF) |

review article
Expanding insights of mitochondrial dysfunction in Parkinson's disease
Patrick M. Abou-Sleiman, Miratul M. K. Muqit and Nicholas W. Wood
Nature Reviews Neuroscience 7, 207–219
(March 2006); doi:10.1038/nrn1868
| Summary | Full Text (HTML / PDF) |

article
Close membrane-membrane proximity induced by Ca2+-dependent multivalent binding of synaptotagmin-1 to phospholipids
Demet Araç, Xiaocheng Chen, Htet A Khant, Josep Ubach, Steven J Ludtke, Masahide Kikkawa, Arthur E Johnson, Wah Chiu, Thomas C Südhof & Josep Rizo
Nature Structural & Molecular Biology 13, 209–217
(March 2006); doi:10.1038/nsmb1056
| Summary | Full Text (HTML / PDF) |

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The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-ß production
Lucia Pastorino, Anyang Sun , Pei-Jung Lu, Xiao Zhen Zhou, Martin Balastik, Greg Finn, Gerburg Wulf, Jormay Lim, Shi-Hua Li, Xiaojiang Li, Weiming Xia, Linda K. Nicholson and Kun Ping Lu
Nature 440, 528–534
(23 March 2006); doi:10.1038/nature04543
| First Paragraph | Full Text (HTML / PDF) |

article
Signaling protein complexes associated with neuronal ion channels
Irwin B Levitan
Nature Neuroscience 13, 278–284
(March 2006); doi:10.1038/nn1647
| Abstract | Full Text (HTML/PDF) |

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A specific amyloid-β protein assembly in the brain impairs memory
Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles G. Glabe, Austin Yang, Michela Gallagher and Karen H. Ashe
Nature 440, 352–357
(16 March 2006); doi:10.1038/nature04533
| First Paragraph | Full Text (HTML / PDF) |

news and views
Alzheimer's disease: A needle from the haystack
Richard Morris and Lennart Mucke
Nature 440, 284–285
(16 March 2006); doi:10.1038/440284a
| Full Text (HTML / PDF) |

review article
Prions and their lethal journey to the brain
Neil A. Mabbott and G. Gordon MacPherson
Nature Reviews Microbiology 4, 201–211
(March 2006); doi:10.1038/nrmicro1346
| Summary | Full Text (HTML / PDF) |

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Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse
Shao-Ping Ji, Yun Zhang, Jamie Van Cleemput, Wen Jiang, Mingxia Liao, Lei Li, Qi Wan, Jon R Backstrom and Xia Zhang
Nature Medicine 12, 324–329
(March 2006); doi:10.1038/nm1349
| First Paragraph | Full Text (HTML/PDF) |

news and views
Plot against pot
Kerrie L Thomas
Nature Medicine 12, 281–283
(March 2006); doi:10.1038/nm0306-281
| Full Text (HTML/PDF) |

article
Myosin II functions in actin-bundle turnover in neuronal growth cones
Nelson A. Medeiros, Dylan T. Burnette and Paul Forscher
Nature Cell Biology 8, 216–226
(March 2006); doi:10.1038/ncb1367
| Abstract | Full Text (HTML/PDF) |

article
Pigment epithelium-derived factor is a niche signal for neural stem cell renewal
Carmen Ramírez-Castillejo, Francisco Sánchez-Sánchez, Celia Andreu-Agulló, Sacri R Ferrón, J Daniel Aroca-Aguilar, Pilar Sánchez, Helena Mira, Julio Escribano and Isabel Fariñas
Nature Neuroscience 9, 331–339
(March 2006); doi:10.1038/nn1657
| Abstract | Full Text (HTML/PDF) |

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PEDF: bridging neurovascular interactions in the stem cell niche
Kevin Pumiglia and Sally Temple
Nature Neuroscience 9, 299–300
(March 2006); doi:10.1038/nn0306-299
| Full Text (HTML/PDF) |

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NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia
I. Micu, Q. Jiang, E. Coderre, A. Ridsdale, L. Zhang, J. Woulfe, X. Yin, B. D. Trapp, J. E. McRory, R. Rehak, G. W. Zamponi, W. Wang and P. K. Stys
Nature 439, 988–992
(23 February 2006); doi:10.1038/nature04474
| First Paragraph | Full Text (HTML / PDF) |

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Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity
Takayuki Kawano, Josef Anrather, Ping Zhou, Laibaik Park, Gang Wang, Kelly A Frys, Alexander Kunz, Sunghee Cho, Marcello Orio and Costantino Iadecola
Nature Medicine 12, 225–229
(February 2006); doi:10.1038/nm1362
| Abstract | Full Text (HTML/PDF) |

article
Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord
Liang-Fong Wong, Ping K Yip, Anna Battaglia, John Grist, Jonathan Corcoran, Malcolm Maden, Mimoun Azzouz, Susan M Kingsman, Alan J Kingsman, Nicholas D Mazarakis and Stephen B McMahon
Nature Neuroscience 9, 243–250
(February 2006); doi:10.1038/nn1622
| Abstract | Full Text (HTML/PDF) |

review article
Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond
Stuart A. Lipton
Nature Reviews Drug Discovery 5, 160–170
(February 2006); doi:10.1038/nrd1958
| Summary | Full Text (HTML / PDF) |

article
Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle
Marçal Vilar, Maribel Murillo-Carretero, Helena Mira, Kalle Magnusson, Valerie Besset and Carlos F Ibáñez
The EMBO Journal advance online publication;
(23 February 2006); doi:10.10.1038/sj.emboj.7601017
| Summary | Full Text (HTML / PDF) |

article
Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease
Lixia Zhao, Qiu-Lan Ma, Frédéric Calon, Marni E Harris-White, Fusheng Yang, Giselle P Lim, Takashi Morihara, Oliver J Ubeda, Surendra Ambegaokar, James E Hansen, Richard H Weisbart, Bruce Teter, Sally A Frautschy and Greg M Cole
Nature Neuroscience 9, 234–242
(February 2006); doi:10.1038/nn1630
| Abstract | Full Text (HTML/PDF) |

review article
The molecular basis for calcium-dependent axon pathfinding
Timothy M. Gomez and James Q. Zheng
Nature Reviews Neuroscience 7, 115–125
(February 2006); doi:10.1038/nrn1844
| Summary | Full Text (HTML / PDF) |

article
Alpha-fetoprotein protects the developing female mouse brain from masculinization and defeminization by estrogens
Julie Bakker, Christelle De Mees, Quentin Douhard, Jacques Balthazart, Philippe Gabant, Josiane Szpirer and Claude Szpirer
Nature Neuroscience 9, 220–226
(February 2006); doi:10.1038/nn1624
| Abstract | Full Text (HTML/PDF) |

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Defending the brain from estrogen
David A Puts, Cynthia L Jordan and S Marc Breedlove
Nature Neuroscience 9, 155–156
(February 2006); doi:10.1038/nn0206-155
| Full Text (HTML/PDF) |

review article
Notch signalling in vertebrate neural development
Angeliki Louvi and Spyros Artavanis-Tsakonas
Nature Reviews Neuroscience 7, 93–102
(February 2006); doi:10.1038/nrn1847
| Summary | Full Text (HTML / PDF) |

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GABA regulates synaptic integration of newly generated neurons in the adult brain
Shaoyu Ge, Eyleen L. K. Goh, Kurt A. Sailor, Yasuji Kitabatake, Guo-li Ming and Hongjun Song
Nature 439, 589–593
(02 February 2006); doi:10.1038/nature04404
| First Paragraph | Full Text (HTML / PDF) |

article
The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons
Frèdèric Marmigére, Andreas Montelius, Michael Wegner, Yoram Groner, Louis F Reichardt and Patrik Ernfors
Nature Neuroscience 9, 180–187
(February 2006); doi:10.1038/nn1631
| Abstract | Full Text (HTML/PDF) |

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Specifying nociceptors
Annette Markus
Nature Neuroscience 9, 162
(February 2006); doi:10.1038/nn0206-162
| Full Text (HTML/PDF) |

article
Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration
Takeshi Kawauchi, Kaori Chihama, Yo-ichi Nabeshima and Mikio Hoshino
Nature Cell Biology 8, 17–26
(January 2006); doi:10.1038/ncb1338
| Abstract | Full Text (HTML/PDF) |

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Cdk5 checks p27kip1 in neuronal migration
Orly Reiner and Tamar Sapir
Nature Cell Biology 8, 11–13
(January 2006); doi:10.1038/ncb0106-11
| Full Text (HTML/PDF) |

review article
Function and regulation of Rnd proteins
Pierre Chardin
Nature Reviews Molecular Cell Biology 7, 54–62
(January 2006); doi:10.1038/nrm1788
| Summary | Full Text (HTML / PDF) |

article
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
Stanislav S Kholmanskikh, Hajira B Koeller, Anthony Wynshaw-Boris, Timothy Gomez, Paul C Letourneau and M Elizabeth Ross
Nature Neuroscience 9, 50–57
(January 2006); doi:10.1038/nn1619
| Abstract | Full Text (HTML/PDF) |

article
A brain-specific microRNA regulates dendritic spine development
Gerhard M. Schratt , Fabian Tuebing, Elizabeth A. Nigh , Christina G. Kane , Mary E. Sabatini, Michael Kiebler and Michael E. Greenberg
Nature 439, 283–289
(19 January 2006); doi:10.1038/nature04367
| Summary | Full Text (HTML / PDF) |

article
DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system
Makoto Sato, Daiki Umetsu, Satoshi Murakami, Tetsuo Yasugi and Tetsuya Tabata
Nature Neuroscience 9, 67–75
(January 2006); doi:10.1038/nn1604
| Abstract | Full Text (HTML/PDF) |

article
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
Makoto Urushitani, Attila Sik, Takashi Sakurai, Nobuyuki Nukina, Ryosuke Takahashi and Jean-Pierre Julien
Nature Neuroscience 9, 108–118
(January 2006); doi:10.1038/nn1603
| Abstract | Full Text (HTML/PDF) |

news and views
Damaging secretions: chromogranins team up with mutant SOD1
Michael Sendtner
Nature Neuroscience 9, 12–14
(January 2006); doi:10.1038/nn0106-12
| Full Text (HTML/PDF) |

technical report
Lipid microarrays identify key mediators of autoimmune brain inflammation
Jennifer L Kanter, Sirisha Narayana, Peggy P Ho, Ingrid Catz, Kenneth G Warren, Raymond A Sobel, Lawrence Steinman and William H Robinson
Nature Medicine 12, 138–143
(January 2006); doi:10.1038/nm1344
| Abstract | Full Text (HTML/PDF) |

article
CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
Jianxi Liu, Maria Asuncion-Chin, Pengchong Liu and Alejandro M Dopico
Nature Neuroscience 9, 41–49
(January 2006); doi:10.1038/nn1602
| Abstract | Full Text (HTML/PDF) |

review article
Astrocyte-endothelial interactions at the blood-brain barrier
N. Joan Abbott, Lars Rönnbäck and Elisabeth Hansson
Nature Reviews Neuroscience 7, 41–53
(January 2006); doi:10.1038/nrn1824
| Summary | Full Text (HTML / PDF) |

article
Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping
Adam M. Schmitt, Jun Shi, Alex M. Wolf, Chin-Chun Lu, Leslie A. King and Yimin Zou
Nature 439, 31–37
(05 January 2006); doi:10.1038/nature04334
| Summary | Full Text (HTML / PDF) |

brief communication
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
Anne Rovelet-Lecrux, Didier Hannequin, Gregory Raux, Nathalie Le Meur, Annie Laquerrière, Anne Vital, Cécile Dumanchin, Sébastien Feuillette, Alexis Brice, Martine Vercelletto, Frédéric Dubas, Thierry Frebourg and Dominique Campion
Nature Genetics 38, 24–26
(January 2006); doi:10.1038/ng1718
| First Paragraph | Full Text (HTML/PDF) |

article
ORL1 receptor-mediated internalization of N-type calcium channels
Christophe Altier, Houman Khosravani, Rhian M Evans, Shahid Hameed, Jean B Peloquin, Brian A Vartian, Lina Chen, Aaron M Beedle, Stephen S G Ferguson, Alexandre Mezghrani, Stefan J Dubel, Emmanuel Bourinet, John E McRory and Gerald W Zamponi
Nature Neuroscience 9, 31–40
(January 2006); doi:10.1038/nn1605
| Abstract | Full Text (HTML/PDF) |

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Internalizing channels: a mechanism to control pain?
Diane Lipscombe and Jesica Raingo
Nature Neuroscience 9, 8–10
(January 2006); doi:10.1038/nn0106-8
| Full Text (HTML/PDF) |

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