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Research library: Nuclear receptors / Nuclear signaling

2003: December | November | October | September | August | July | June | May | April | March | February | January

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article
Muscle-specific Pparg deletion causes insulin resistance
Andrea L Hevener, Weimin He, Yaacov Barak, Jamie Le, Gautam Bandyopadhyay, Peter Olson, Jason Wilkes, Ronald M Evans and Jerrold Olefsky
Nature Medicine 9, 1491–1497
(December 2003); doi:10.1038/nm956
| Abstract | Full Text (HTML/PDF) |

letters to nature
An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation
Athula H. Wikramanayake, Melanie Hong, Patricia N. Lee, Kevin Pang, Christine A. Byrum, Joanna M. Bince, Ronghui Xu and Mark Q. Martindale
Nature 426, 446–450
(27 November 2003); doi:10.1038/nature02113
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-γ
Stephan Herzig, Susan Hedrick, Ianessa Morantte, Seung-Hoi Koo, Francesco Galimi and Marc Montminy
Nature 426, 190–193
(13 November 2003); doi:10.1038/nature02110
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila
Yurii Sedkov, Elizabeth Cho, Svetlana Petruk, Lucy Cherbas, Sheryl T. Smith, Richard S. Jones, Peter Cherbas, Eli Canaani, James B. Jaynes and Alexander Mazo
Nature 426, 78–83
(06 November 2003); doi:10.1038/nature02080
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor
Isabelle M. L. Billas, Thomas Iwema, Jean-Marie Garnier, André Mitschler, Natacha Rochel and Dino Moras
Nature 426, 91–96
(06 November 2003); doi:10.1038/nature02112
| First Paragraph | Full Text (HTML / PDF) |

article
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
Nobunao Wakabayashi, Ken Itoh, Junko Wakabayashi, Hozumi Motohashi, Shuhei Noda, Satoru Takahashi, Sumihisa Imakado, Tomoe Kotsuji, Fujio Otsuka, Dennis R Roop, Takanori Harada, James Douglas Engel and Masayuki Yamamoto
Nature Genetics 35, 238–245
(November 2003); doi:10.1038/ng1248
| Abstract | Full Text (HTML/PDF) |

news and views
A keaper and a striker maintain epidermal homeostasis
Thomas M Magin
Nature Genetics 35, 202–204
(November 2003); doi:10.1038/ng1103-202
| Full Text (HTML/PDF) |

review article
The nuclear pore complex: nucleocytoplasmic transport and beyond
Birthe Fahrenkrog and Ueli Aebi
Nature Reviews Molecular Cell Biology 4, 757–766
(October 2003); doi:10.1038/nrm1230
| Abstract | Full Text (HTML / PDF) |

letter
T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation
Judson A Brewer, Bernard Khor, Sherri K Vogt, Lisa M Muglia, Hideji Fujiwara, Karen E Haegele, Barry P Sleckman and Louis J Muglia
Nature Medicine 9, 1318–1322
(October 2003); doi:10.1038/nm895
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
Anne-Sophie Van Laere, Minh Nguyen, Martin Braunschweig, Carine Nezer, Catherine Collette, Laurence Moreau, Alan L. Archibald, Chris S. Haley, Nadine Buys, Michael Tally, Góran Andersson, Michel Georges and Leif Andersson
Nature 425, 832–836
(23 October 2003); doi:10.1038/nature02064
| First Paragraph | Full Text (HTML / PDF) |

news and views
Genetics: Secret of a porkie porker
Chris Gunter
Nature 425, 777–778
(23 October 2003); doi:10.1038/425777b
| Full Text (HTML / PDF) |

brief communication
Genetic deficiency in Pparg does not alter development of experimental prostate cancer
Enrique Saez, Peter Olson and Ronald M Evans
Nature Medicine 9, 1265–1266
(October 2003); doi:10.1038/nm928
| First Paragraph | Full Text (HTML/PDF) |

review article
Smad-dependent and Smad-independent pathways in TGF-β family signalling
Rik Derynck and Ying E. Zhang
Nature 425, 577–584
(09 October 2003); doi:10.1038/nature02006
| Abstract | Full Text (HTML / PDF) |

article
All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ
Catherine Stehlin-Gaon, Dominica Willmann, Denis Zeyer, Sarah Sanglier, Alain Van Dorsselaer, Jean-Paul Renaud, Dino Moras and Roland Schüle
Nature Structural Biology 10, 820–825
(October 2003); doi:10.1038/nsb979
| Abstract | Full Text (HTML/PDF) |

review article
Nuclear and unclear functions of SUMO
Jacob-S. Seeler and Anne Dejean
Nature Reviews Molecular Cell Biology 4, 690–699
(September 2003); doi:10.1038/nrm1200
| Abstract | Full Text (HTML / PDF) |

letters to nature
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
Jin Fu, Silvana Gaetani, Fariba Oveisi, Jesse Lo Verme, Antonia Serrano, Fernando Rodríguez de Fonseca, Anja Rosengarth, Hartmut Luecke, Barbara Di Giacomo, Giorgio Tarzia and Daniele Piomelli
Nature 425, 90–93
(04 September 2003); doi:10.1038/nature01921
| First Paragraph | Full Text (HTML / PDF) |

article
Dexamethasone induction of hypertension and diabetes is PPAR-α dependent in LDL receptor-null mice
Carlos Bernal-Mizrachi, Sherry Weng, Chu Feng, Brian N. Finck, Russell H. Knutsen, Teresa C. Leone, Trey Coleman, Robert P. Mecham, Daniel P. Kelly and Clay F. Semenkovich
Nature Medicine 9, 1069–1075
(August 2003); doi:10.1038/nm898
| Abstract | Full Text (HTML/PDF) |

letter
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis
Fereshteh Parviz, Christine Matullo, Wendy D. Garrison, Laura Savatski, John W. Adamson, Gang Ning, Klaus H. Kaestner, Jennifer M. Rossi, Kenneth S. Zaret and Stephen A. Duncan
Nature Genetics 34, 292–296
(July 2003); doi:10.1038/ng1175
| First Paragraph | Full Text (HTML/PDF) |

letter
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
Arkady Celeste, Oscar Fernandez-Capetillo, Michael J. Kruhlak, Duane R. Pilch, David W. Staudt, Alicia Lee, Robert F. Bonner, William M. Bonner and André Nussenzweig
Nature Cell Biology 5, 675–679
(July 2003); doi:10.1038/ncb1004
| First Paragraph | Full Text (HTML/PDF) |

letters to nature
Histone H3 phosphorylation by IKK-α is critical for cytokine-induced gene expression
Yumi Yamamoto, Udit N. Verma, Shashi Prajapati, Youn-Tae Kwak and Richard B. Gaynor
Nature 423, 655–659
(05 June 2003); doi:10.1038/nature01576
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
A nucleosomal function for IκB kinase-α in NF-κB-dependent gene expression
Vasiliki Anest, Julie L. Hanson, Patricia C. Cogswell, Kris A. Steinbrecher, Brian D. Strahl and Albert S. Baldwin
Nature 423, 659–663
(05 June 2003); doi:10.1038/nature01648
| First Paragraph | Full Text (HTML / PDF) |

news and views
Signal transduction: A regulator branches out
Alain Israël
Nature 423, 596–597
(05 June 2003); doi:10.1038/423596a
| Full Text (HTML / PDF) |

news and views
IKKα: a chromatin modifier
Sowmya Swaminathan
Nature Cell Biology 5, 503
(June 2003); doi:10.1038/ncb0603-503
| Full Text (HTML/PDF) |

letters to nature
Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors
Zhulun Wang, Gérard Benoit, Jinsong Liu, Srividya Prasad, Piia Aarnisalo, Xiaohong Liu, Haoda Xu, Nigel P. C. Walker and Thomas Perlmann
Nature 423, 555–560
(29 May 2003); doi:10.1038/nature01645
| First Paragraph | Full Text (HTML / PDF) |

letter
Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum
Wihelma Echevarría, M. Fatima Leite, Mateus T. Guerra, Warren R. Zipfel and Michael H. Nathanson
Nature Cell Biology 5, 440–446
(May 2003); doi:10.1038/ncb980
| First Paragraph | Full Text (HTML/PDF) |

article
Tissue-specific nuclear architecture and gene expession regulated by SATB1
Shutao Cai, Hye-Jung Han and Terumi Kohwi-Shigematsu
Nature Genetics 34, 42–51
(May 2003); doi:10.1038/ng1146
| Abstract | Full Text (HTML/PDF) |

news and views
A nuclear address with influence
M. Frances Shannon
Nature Genetics 34, 4–6
(May 2003); doi:10.1038/ng0503-4
| Full Text (HTML/PDF) |

brief communication
Dax1 is required for testis determination
Joshua J. Meeks, Jeffrey Weiss and J. Larry Jameson
Nature Genetics 34, 32–33
(May 2003); doi:10.1038/ng1141
| First Paragraph | Full Text (HTML/PDF) |

letter
Translokin is an intracellular mediator of FGF-2 trafficking
Carine Bossard, Henrik Laurell, Loïc Van den Berghe, Sylvain Meunier, Catherine Zanibellato and Hervé Prats
Nature Cell Biology 5, 433–439
(May 2003); doi:10.1038/ncb979
| First Paragraph | Full Text (HTML/PDF) |

news and views
Small changes in Wnt signalling
Sarah Greaves
Nature Cell Biology 5, 387
(May 2003); doi:10.1038/ncb0503-387
| Full Text (HTML/PDF) |

review article
Nuclear lipid signalling
Robin F. Irvine
Nature Reviews Molecular Cell Biology 4, 349–361
(May 2003); doi:10.1038/nrm1100
| Summary | Full Text (HTML / PDF) |

letters to nature
Chibby, a nuclear β-catenin-associated antagonist of the Wnt/Wingless pathway
Ken-Ichi Takemaru, Shinji Yamaguchi, Young Sik Lee, Yang Zhang, Richard W. Carthew and Randall T. Moon
Nature 422, 905–909
(24 April 2003); doi:10.1038/nature01570
| First Paragraph | Full Text (HTML / PDF) |

letter
Cytokines suppress adipogenesis and PPAR-γ function through the TAK1/TAB1/NIK cascade
Miyuki Suzawa, Ichiro Takada, Junn Yanagisawa, Fumiaki Ohtake, Satoko Ogawa, Toshimasa Yamauchi, Takashi Kadowaki, Yasuhiro Takeuchi, Hiroshi Shibuya, Yukiko Gotoh, Kunihiro Matsumoto and Shigeaki Kato
Nature Cell Biology 5, 224–230
(March 2003); doi:10.1038/ncb942
| First Paragraph | Full Text (HTML/PDF) |

letter
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
Claudia Lukas, Jacob Falck, Jirina Bartkova, Jiri Bartek and Jiri Lukas
Nature Cell Biology 5, 255–260
(March 2003); doi:10.1038/ncb945
| First Paragraph | Full Text (HTML/PDF) |

perspectives
Armadillo/β-catenin signals in the nucleus - proof beyond a reasonable doubt?
Mariann Bienz and Hans Clevers
Nature Cell Biology 5, 179–182
(March 2003); doi:10.1038/ncb0303-179
| Full Text (HTML/PDF) |

article
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
Sean B. Joseph, Antonio Castrillo, Bryan A. Laffitte, David J. Mangelsdorf and Peter Tontonoz
Nature Medicine 9, 213–219
(February 2003); doi:10.1038/nm820
| Abstract | Full Text (HTML/PDF) |

news and views
eLiXiRs for restraining inflammation
Mason W. Freeman and Kathryn J. Moore
Nature Medicine 9, 168–169
(February 2003); doi:10.1038/nm0203-168
| Full Text (HTML/PDF) |

article
The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
Rommel G. Tirona, Wooin Lee, Brenda F. Leake, Lu-Bin Lan, Cynthia Brimer Cline, Vishal Lamba, Fereshteh Parviz, Stephen A. Duncan, Yusuke Inoue, Frank J. Gonzalez, Erin G. Schuetz and Richard B. Kim
Nature Medicine 9, 220–224
(February 2003); doi:10.1038/nm815
| Abstract | Full Text (HTML/PDF) |

article
Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins
Vikram Govind Panse, Bernhard Küster, Thomas Gerstberger and Ed Hurt
Nature Cell Biology 5, 21–27
(January 2003); doi:10.1038/ncb893
| Abstract | Full Text (HTML/PDF) |

article
In vivo imaging of transcriptionally active estrogen receptors
Paolo Ciana, Michele Raviscioni, Paola Mussi, Elisabetta Vegeto, Ivo Que, Malcolm G. Parker, Clemens Lowik and Adriana Maggi
Nature Medicine 9, 82–86
(January 2003); doi:10.1038/nm809
| Abstract | Full Text (HTML/PDF) |

news and views
In vivo imaging reveals estrogen receptor's hidden personality
Geoffrey L. Greene
Nature Medicine 9, 22–23
(January 2003); doi:10.1038/nm0103-22
| Full Text (HTML/PDF) |

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