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Research library: Nuclear receptors / Nuclear signaling

2007: December | November | October | September | August | July | June | May | April | March | January

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article
Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ
Srilatha Raghuram et al.
Nature Structural & Molecular Biology 14, 1207–1213
(December 2007); doi:10.1038/nsmb1344
| Summary | Full Text (HTML / PDF) |

letter
PPAR-γ regulates osteoclastogenesis in mice
Yihong Wan, Ling-Wa Chong & Ronald M Evans
Nature Medicine 13, 1496–1503
(December 2007); doi:10.1038/nm1672
| Summary | Full Text (HTML / PDF) |

letter
Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha
Konstantin Khetchoumian et al.
Nature Genetics 39, 1500–1506
(December 2007); doi:10.1038/ng.2007.15
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article
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation
Ichiro Takada et al.
Nature Cell Biology 9, 1273–1285
(November 2007); doi:10.1038/ncb1647
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news and views
Fat or bone? A non-canonical decision
Thomas Günther & Roland Schüle
Nature Cell Biology 9, 1229–1231
(November 2007); doi:10.1038/ncb1107-1229
| Summary | Full Text (HTML / PDF) |

review
Retinoic acid in the development, regeneration and maintenance of the nervous system
Malcolm Maden
Nature Reviews Neuroscience 8, 755–765
(October 2007); doi:10.1038/nrn2212
| Summary | Full Text (HTML / PDF) |

letter
Inhibition of Crm1–p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation
Masayuki Kanai et al.
Nature Cell Biology 9, 1175–1183
(October 2007); doi:10.1038/ncb1638
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review
Exporting RNA from the nucleus to the cytoplasm
Alwin Köhler & Ed Hurt
Nature Reviews Molecular Cell Biology 8, 761–773
(October 2007); doi:10.1038/nrm2255
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article
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen
Michihisa Umetani et al.
Nature Medicine 13, 1185–1192
(October 2007); doi:10.1038/nm1641
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review
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
Weidong Wang
Nature Reviews Genetics 8, 735–748
(October 2007); doi:10.1038/nrg2159
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review
RAR and RXR modulation in cancer and metabolic disease
Lucia Altucci, Mark D. Leibowitz, Kathleen M. Ogilvie, Angel R. de Lera & Hinrich Gronemeyer
Nature Reviews Drug Discovery 6, 793–810
(October 2007); doi:10.1038/nrd2397
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review
Design of selective nuclear receptor modulators: RAR and RXR as a case study
Angel R. de Lera, William Bourguet, Lucia Altucci & Hinrich Gronemeyer
Nature Reviews Drug Discovery 6, 811–820
(October 2007); doi:10.1038/nrd2398
| Summary | Full Text (HTML / PDF) |

perspective
Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
Kelly A. Green & Jason S. Carroll
Nature Reviews Cancer 7, 713–722
(September 2007); doi:10.1038/nrc2211
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review
The role of nuclear architecture in genomic instability and ageing
Philipp Oberdoerffer & David A. Sinclair
Nature Reviews Molecular Cell Biology 8, 692–702
(September 2007); doi:10.1038/nrm2238
| Summary | Full Text (HTML / PDF) |

review
Vitamin D signalling pathways in cancer: potential for anticancer therapeutics
Kristin K. Deeb, Donald L. Trump & Candace S. Johnson
Nature Reviews Cancer 7, 684–700
(September 2007); doi:10.1038/nrc2196
| Summary | Full Text (HTML / PDF) |

perspective
Treating prostate cancer: a rationale for targeting local oestrogens
Stuart J. Ellem & Gail P. Risbridger
Nature Reviews Cancer 7, 621–627
(August 2007); doi:10.1038/nrc2174
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letter
Molecular basis for the functional interaction of dynein light chain with the nuclear-pore complex
Philipp Stelter, Ruth Kunze, Dirk Flemming, Dominic Höpfner, Meikel Diepholz, Peter Philippsen, Bettina Böttcher & Ed Hurt
Nature Cell Biology 9, 788–796
(July 2007); doi:10.1038/ncb1604
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letter
Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia
Shannon E Mullican, Shuo Zhang, Marina Konopleva, Vivian Ruvolo, Michael Andreeff, Jeffrey Milbrandt & Orla M Conneely
Nature Medicine 13, 730–735
(June 2007); doi:10.1038/nm1579
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scientific report
Structural plasticity in the oestrogen receptor ligand-binding domain
Kendall W Nettles, John B Bruning, German Gil, Erin E O'Neill, Jason Nowak, Alun Hughs, Younchang Kim, Eugene R DeSombre, Robert Dilis, Robert N Hanson, Andrzej Joachimiak & Geoffrey L Greene
EMBO Reports 8, 563–568
(June 2007); doi:10.1038/sj.embor.7400963
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article
Retinaldehyde represses adipogenesis and diet-induced obesity
Ouliana Ziouzenkova, Gabriela Orasanu, Molly Sharlach, Taro E Akiyama, Joel P Berger, Jason Viereck, James A Hamilton, Guangwen Tang, Gregory G Dolnikowski, Silke Vogel, Gregg Duester & Jorge Plutzky
Nature Medicine 13, 695–702
(June 2007); doi:10.1038/nm1587
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news and views
Retinaldehyde: more than meets the eye
Béatrice Desvergne
Nature Medicine 13, 671–673
(June 2007); doi:10.1038/nm0607-671
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review
Nuclear microenvironments in biological control and cancer
Sayyed K. Zaidi, Daniel W. Young, Amjad Javed, Jitesh Pratap, Martin Montecino, Andre van Wijnen, Jane B. Lian, Janet L. Stein & Gary S. Stein
Nature Reviews Cancer 7, 454–463
(June 2007); doi:10.1038/nrc2149
| Summary | Full Text (HTML / PDF) |

scientific report
Structural plasticity in the oestrogen receptor ligand-binding domain
Kendall W Nettles, John B Bruning, German Gil, Erin E O'Neill, Jason Nowak, Alun Hughs, Younchang Kim, Eugene R DeSombre, Robert Dilis, Robert N Hanson, Andrzej Joachimiak & Geoffrey L Greene
EMBO Reports 8, 563–568
(June 2007); doi:10.1038/sj.embor.7400963
| Summary | Full Text (HTML / PDF) |

letter
Serotonin and neuropeptide F have opposite modulatory effects on fly aggression
Herman A Dierick & Ralph J Greenspan
Nature Genetics 39, 678–682
(May 2007); doi:10.1038/ng2029
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news and views
Road rage and fruit flies
Anne F Simon & David E Krantz
Nature Genetics 39, 581–582
(May 2007); doi:10.1038/ng0507-581
| Summary | Full Text (HTML / PDF) |

letter
Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer
Frederik Holst, Phillip R Stahl, Christian Ruiz, Olaf Hellwinkel, Zeenath Jehan, Marc Wendland, Annette Lebeau, Luigi Terracciano, Khawla Al-Kuraya, Fritz Jänicke, Guido Sauter & Ronald Simon
Nature Genetics 39, 655–660
(May 2007); doi:10.1038/ng2006
| Summary | Full Text (HTML / PDF) |

brief communication
Structure-based design of a pathway-specific nuclear import inhibitor
Ahmet E Cansizoglu, Brittany J Lee, Zi Chao Zhang, Beatriz M A Fontoura & Yuh Min Chook
Nature Structural & Molecular Biology 14, 452–454
(May 2007); doi:10.1038/nsmb1229
| Summary | Full Text (HTML / PDF) |

letter
Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2
Xiaobo Wang, Karine Belguise, Nathalie Kersual, Kathrin H. Kirsch, Nora D. Mineva, Florence Galtier, Dany Chalbos & Gail E. Sonenshein
Nature Cell Biology 9, 470–478
(April 2007); doi:10.1038/ncb1559
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news and views
NF-κB links oestrogen receptor signalling and EMT
Derek C. Radisky & Mina J. Bissell
Nature Cell Biology 9, 361–363
(April 2007); doi:10.1038/ncb0407-361
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letter
Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation
Ralph Gareus, Marion Huth, Bernadette Breiden, Arianna Nenci, Nora Rösch, Ingo Haase, Wilhelm Bloch, Konrad Sandhoff & Manolis Pasparakis
Nature Cell Biology 9, 461–469
(April 2007); doi:10.1038/ncb1560
| Summary | Full Text (HTML / PDF) |

letter
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
Fumiaki Ohtake, Atsushi Baba, Ichiro Takada, Maiko Okada, Kei Iwasaki, Hiromi Miki, Sayuri Takahashi, Alexander Kouzmenko, Keiko Nohara, Tomoki Chiba, Yoshiaki Fujii-Kuriyama & Shigeaki Kato
Nature 446, 562–566
(29 March 2007); doi:10.1038/nature05683
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letter
Vitamin B6 conjugation to nuclear corepressor RIP140 and its role in gene regulation
M D Mostaqul Huq, Nien-Pei Tsai, Ya-Ping Lin, LeeAnn Higgins and Li-Na Wei
Nature Chemical Biology 3, 161–165
(March 2007); doi:10.1038/nchembio861
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article
ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor
Zhiming Yang, Yu-Jia Chang, I-Chen Yu, Shuyuan Yeh, Cheng-Chia Wu, Hiroshi Miyamoto, Diane E Merry, Gen Sobue, Lu-Min Chen, Shu-Shi Chang & Chawnshang Chang
Nature Medicine 13, 348–353
(March 2007); doi:10.1038/nm1547
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article
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment pp340
Liam R Brunham, Janine K Kruit, Terry D Pape, Jenelle M Timmins, Anne Q Reuwer, Zainisha Vasanji, Brad J Marsh, Brian Rodrigues, James D Johnson, John S Parks, C Bruce Verchere & Michael R Hayden
Nature Medicine 13, 340–347
(March 2007); doi:10.1038/nm1546
| Summary | Full Text (HTML / PDF) |

letter
The nuclear receptor LXR is a glucose sensor
Nico Mitro, Puiying A. Mak, Leo Vargas, Cristina Godio, Eric Hampton, Valentina Molteni, Andreas Kreusch and Enrique Saez
Nature 445, 219–223
(11 January 2007); doi:10.1038/nature05449
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