article The antioxidant function of the p53 tumor suppressor
Anna A Sablina, Andrei V Budanov, Galina V Ilyinskaya, Larissa S Agapova, Julia E Kravchenko and Peter M Chumakov Nature Medicine11, 1306–1313
(December 2005); doi:10.1038/nm1320
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November
review article Mitochondrial tumour suppressors: a genetic and biochemical update
Eyal Gottlieb and Ian P. M. Tomlinson Nature Reviews Cancer5, 857–866
(November 2005); doi:10.1038/nrc1737
| Abstract | Full Text (HTML / PDF) |
October
article BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
Ryan T Phan, Masumichi Saito, Katia Basso, Huifeng Niu and Riccardo Dalla-Favera Nature Immunology6, 1054–1060
(October 2005); doi:10.1038/ni1245
| Abstract | Full Text (HTML/PDF) |
news and views A-Miz-ing BCL6
Xiaosheng Wu and Diane F Jelinek Nature Immunology6, 964–966
(October 2005); doi:10.1038/ni1005-964
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September
letter Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
Ignacio Varela, Juan Cadiñanos, Alberto M. Pendás, Ana Gutiérrez-Fernández, Alicia R. Folgueras, Luis M. Sánchez, Zhongjun Zhou, Francisco J. Rodríguez, Colin L. Stewart, José A Vega, Karl Tryggvason, José M. P. Freije and Carlos López-Otín Nature437, 564–568
(22 September 2005); doi:10.1038/nature04019
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brief communication The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia
Orna Levran, Claire Attwooll, Rashida T Henry, Kelly L Milton, Kornelia Neveling, Paula Rio, Sat Dev Batish, Reinhard Kalb, Eunike Velleuer, Sandra Barral, Jurg Ott, John Petrini, Detlev Schindler, Helmut Hanenberg and Arleen D Auerbach Nature Genetics37, 931–933
(September 2005); doi:10.1038/ng1624
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article The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway
Georgina Mosedale, Wojciech Niedzwiedz, Arno Alpi, Franco Perrina, Jose B Pereira-Leal, Mark Johnson, Frederic Langevin, Paul Pace and Ketan J Patel Nature Structural and Molecular Biology12, 763–771
(September 2005); doi:10.1038/nsmb981
| Abstract | Full Text (HTML/PDF) |
August
review article Transcriptional regulation and transformation by Myc proteins
Sovana Adhikary and Martin Eilers Nature Reviews Molecular Cell Biology6, 635–645
(August 2005); doi:10.1038/nrm1703
| Summary | Full Text (HTML / PDF) |
review article The TCL1 family of oncoproteins: co-activators of transformation
Michael A. Teitell Nature Reviews Cancer5, 640–648
(August 2005); doi:10.1038/nrc1672
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review article Using Drosophila melanogaster to map human cancer pathways
Anthony M. Brumby and Helena E. Richardson Nature Reviews Cancer5, 626–639
(August 2005); doi:10.1038/nrc1671
| Abstract | Full Text (HTML / PDF) |
article Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
Michael T. Hemann, Anka Bric, Julie Teruya-Feldstein, Andreas Herbst, Jonas A. Nilsson, Carlos Cordon-Cardo, John L. Cleveland, William P. Tansey and Scott W. Lowe Nature436, 807–811
(11 August 2005); doi:10.1038/nature03845
| Abstract | Full Text (HTML / PDF) |
news and views Cancer: Two in one
Anton Berns Nature436, 787–789
(11 August 2005); doi:10.1038/436787a
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article Oncogene-induced senescence as an initial barrier in lymphoma development
Melanie Braig, Soyoung Lee, Christoph Loddenkemper, Cornelia Rudolph, Antoine H.F.M. Peters, Brigitte Schlegelberger, Harald Stein, Bernd Dörken, Thomas Jenuwein and Clemens A. Schmitt Nature436, 660–665
(04 August 2005); doi:10.1038/nature03841
| Abstract | Full Text (HTML / PDF) |
letter Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
Zhenbang Chen, Lloyd C. Trotman, David Shaffer, Hui-Kuan Lin, Zohar A. Dotan, Masaru Niki, Jason A. Koutcher, Howard I. Scher, Thomas Ludwig, William Gerald, Carlos Cordon-Cardo and Pier Paolo Pandolfi Nature436, 725–730
(04 August 2005); doi:10.1038/nature03918
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letter BRAFE600-associated senescence-like cell cycle arrest of human naevi
Chrysiis Michaloglou, Liesbeth C. W. Vredeveld, Maria S. Soengas, Christophe Denoyelle, Thomas Kuilman, Chantal M. A. M. van der Horst, Donné M. Majoor, Jerry W. Shay, Wolter J. Mooi and Daniel S. Peeper Nature436, 720–724
(04 August 2005); doi:10.1038/nature03890
| First Paragraph | Full Text (HTML / PDF) |
brief communications Tumour biology: Senescence in premalignant tumours
Manuel Collado, Jesús Gil, Alejo Efeyan, Carmen Guerra, Alberto J. Schuhmacher, Marta Barradas, Alberto Benguría, Angel Zaballos, Juana M. Flores, Mariano Barbacid, David Beach and Manuel Serrano Nature436, 642
(04 August 2005); doi:10.1038/436642a
| First Paragraph | Full Text (HTML / PDF) |
news and views Cancer: Crime and punishment
Norman E. Sharpless and Ronald A. DePinho Nature436, 636–637
(04 August 2005); doi:10.1038/436636a
| Full Text (HTML / PDF) |
review article Id family of helix-loop-helix proteins in cancer
Jonathan Perk, Antonio Iavarone and Robert Benezra Nature Reviews Cancer5, 603–614
(August 2005); doi:10.1038/nrc1673
| Abstract | Full Text (HTML / PDF) |
July
letter Use of human tissue to assess the oncogenic activity of melanoma-associated mutations
Yakov Chudnovsky, Amy E Adams, Paul B Robbins, Qun Lin and Paul A Khavari Nature Genetics37, 745–749
(July 2005); doi:10.1038/ng1586
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review article The anaemia of
cancer: death by a thousand cuts Jerry L. Spivak Nature Reviews
Cancer5, 543–555 (July 2005); doi:10.1038/nrc1648 | Abstract | Full Text (HTML /
PDF) |
letter Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
Levi A. Garraway, Hans R. Widlund, Mark A. Rubin, Gad Getz, Aaron J. Berger, Sridhar Ramaswamy, Rameen Beroukhim, Danny A. Milner, Scott R. Granter, Jinyan Du, Charles Lee, Stephan N. Wagner, Cheng Li, Todd R. Golub , David L. Rimm, Matthew L. Meyerson , David E. Fisher and William R. Sellers Nature436, 117–122
(07 July 2005); doi:10.1038/nature03664
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article Temporal dissection of p53 function in vitro and in vivo
Maria A Christophorou, Dionisio Martin-Zanca, Laura Soucek, Elizabeth R Lawlor, Lamorna Brown-Swigart, Emmy W Verschuren and Gerard I Evan Nature Genetics37, 718–726
(July 2005); doi:10.1038/ng1572
| Abstract | Full Text (HTML/PDF) |
June
letter A microRNA polycistron as a potential human oncogene
Lin He, J. Michael Thomson, Michael T. Hemann, Eva Hernando-Monge, David Mu, Summer Goodson, Scott Powers, Carlos Cordon-Cardo, Scott W. Lowe, Gregory J. Hannon and Scott M. Hammond Nature435, 828–833
(09 June 2005); doi:10.1038/nature03552
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letter c-Myc-regulated microRNAs modulate E2F1 expression
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang and Joshua T. Mendell Nature435, 839–843
(09 June 2005); doi:10.1038/nature03677
| First Paragraph | Full Text (HTML / PDF) |
news and views Cancer genomics: Small RNAs with big impacts
Paul S. Meltzer Nature435, 745–746
(09 June 2005); doi:10.1038/435745a
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