article Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu, John R. Jeffers, Gerard P. Zambetti, James J.-D. Hsieh & Emily H.-Y. Cheng Nature Cell Biology8, 1348–1358
(December 2006); doi:10.1038/ncb1499
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news and views Upgrading the BCL-2 Network
Heidi L. Galonek & J. Marie Hardwick Nature Cell Biology8, 1317–1319
(December 2006); doi:10.1038/ncb1206-1317
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review Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
Franck Toledo and Geoffrey M. Wahl Nature Reviews Cancer6, 906–923
(December 2006); doi:10.1038/nrc2012
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letter Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F. Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C. Zoumpourlis, Munenori Takaoka, Hiroshi Nakagawa, Frederic Tort, Kasper Fugger, Fredrik Johansson, Maxwell Sehested, Claus L. Andersen, Lars Dyrskjot, Torben Ørntoft, Jiri Lukas, Christos Kittas, Thomas Helleday, Thanos D. Halazonetis, Jiri Bartek and Vassilis G. Gorgoulis Nature444, 633–637
(30 November 2006); doi:10.1038/nature05268
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November
Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
Victoria Aranda, Teresa Haire, Marissa E. Nolan, Joseph P. Calarco, Avi Z. Rosenberg, James P. Fawcett, Tony Pawson & Senthil K. Muthuswamy Nature Cell Biology8, 1235–1245
(November 2006); doi:10.1038/ncb1485
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article Inactivation of the p53 pathway in retinoblastoma
Nikia A. Laurie, Stacy L. Donovan, Chie-Schin Shih, Jiakun Zhang, Nicholas Mills, Christine Fuller, Amina Teunisse, Suzanne Lam, Yolande Ramos, Adithi Mohan, Dianna Johnson, Matthew Wilson, Carlos Rodriguez-Galindo, Micaela Quarto, Sarah Francoz, Susan M. Mendrysa, R. Kiplin Guy, Jean-Christophe Marine, Aart G. Jochemsen and Michael A. Dyer Nature444, 61–66
(02 November 2006); doi:10.1038/nature05194
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news and views Cancer biology: Second step to retinal tumours
Valerie A. Wallace Nature444, 45–46
(02 November 2006); doi:10.1038/444045a Full Text (HTML / PDF) |
September
letter Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing
Anna V. Molofsky, Shalom G. Slutsky, Nancy M. Joseph, Shenghui He, Ricardo Pardal, Janakiraman Krishnamurthy, Norman E. Sharpless and Sean J. Morrison Nature443, 448–452
(28 September 2006); doi:10.1038/nature05091
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letter p16INK4a induces an age-dependent decline in islet regenerative potential
Janakiraman Krishnamurthy, Matthew R. Ramsey, Keith L. Ligon, Chad Torrice, Angela Koh, Susan Bonner-Weir and Norman E. Sharpless Nature443, 453–457
(28 September 2006); doi:10.1038/nature05092
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news and views Ageing: Balancing regeneration and cancer
Christian M Beausejour and Judith Campisi Nature AOP (27 September 2006); doi:10.1038/nature05221
| Full Text (HTML / PDF) |
letter Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice
Mei Ding, Shiying Cui, Chengjin Li, Serge Jothy, Volker Haase, Brent M Steer, Philip A Marsden, Jeffrey Pippin, Stuart Shankland, Maria Pia Rastaldi, Clemens D Cohen, Matthias Kretzler & Susan E Quaggin Nature Medicine12, 1081–1087
(2006); doi:10.1038/nm1460
| Summary |
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news and views Hypoxia pathway linked to kidney failure
Gregg L Semenza Nature Medicine12, 996–997
(2006); doi:10.1038/nm0906-996
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letter The tumour suppressor Hippo acts with the NDR kinases in dendritic tiling and maintenance
Kazuo Emoto, Jay Z. Parrish, Lily Yeh Jan and Yuh-Nung Jan Nature443, 210–213
(14 September 2006); doi:10.1038/nature05090
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letter The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
M. A. Christophorou, I. Ringshausen, A. J. Finch, L. Brown Swigart and G. I. Evan Nature443, 214–217
(14 September 2006); doi:10.1038/nature05077
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review Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all
Jesús Gil1 and Gordon Peters Nature Reviews Molecular Cell Biology7, 667–677
(2006); doi:10.1038/nrm1987
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letter Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
Michael Dews, Asal Homayouni, Duonan Yu, Danielle Murphy, Cinzia Sevignani, Erik Wentzel, Emma E Furth, William M Lee, Greg H Enders, Joshua T Mendell & Andrei Thomas-Tikhonenko Nature Genetics12, 1060–1065
(2006); doi:10.1038/ng1855
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article Cool-1 functions as an essential regulatory node for EGFreceptor- and Src-mediated cell growth
Qiyu Feng, Dan Baird, Xu Peng, Jianbin Wang, Thi Ly, Jun-Lin Guan & Richard A. Cerione Nature Cell Biology8, 945–956
(September 2006); doi:10.1038/ncb1453
| Summary | Full Text (HTML / PDF) |
news and views Src transforms in a Cool way
Jeffrey R. Peterson & Jonathan Chernoff Nature Cell Biology8, 905–907
(September 2006); doi:10.1038/ncb0906-905
| Summary | Full Text (HTML / PDF) |
review Divorcing ARF and p53: an unsettled case
Charles J. Sherr Nature Reviews Cancer7, 663–673
(September 2006); doi:10.1038/nrc1954
| Summary | Full Text (HTML / PDF) |
August
article PML inhibits HIF-1α translation and neoangiogenesis through repression of mTOR
Rosa Bernardi, Ilhem Guernah, David Jin, Silvia Grisendi, Andrea Alimonti, Julie Teruya-Feldstein, Carlos Cordon-Cardo, M. Celeste Simon, Shahin Rafii and Pier Paolo Pandolfi Nature442, 779–785
(10 August 2006); doi:10.1038/nature05029
| Summary | Full Text (HTML / PDF) |
letter Interaction of KAI1 on tumor cells with DARC on vascular endothelium leads to metastasis suppression
Sucharita Bandyopadhyay, Rui Zhan, Asok Chaudhuri, Misako Watabe, Sudha K Pai, Shigeru Hirota, Sadahiro Hosobe, Taisei Tsukada, Kunio Miura, Yukio Takano, Ken Saito, Mary E Pauza, Sunao Hayashi, Ying Wang, Sonia Mohinta, Tomoyuki Mashimo, Megumi Iiizumi, Eiji Furuta & Kounosuke Watabe Nature Medicine12, 933–938
(10 August 2006); doi:10.1038/nm1444
| Summary | Full Text (HTML / PDF) |
news and views Stopping cancer before it colonizes
Carrie W Rinker-Schaeffer & Jonathan A Hickson Nature Medicine12, 887–888
(10 August 2006); doi:10.1038/nm0806-887
| Summary | Full Text (HTML / PDF) |
article Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice
Pengyuan Liu, Yian Wang, Haris Vikis, Anna Maciag, Daolong Wang, Yan Lu, Yan Liu & Ming You Nature Genetics38, 888–895
(10 August 2006); doi:10.1038/ng1849
| Summary | Full Text (HTML / PDF) |
article The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl–Crk pathway
Nicole K. Noren, Gabriele Foos, Craig A. Hauser & Elena B. Pasquale Nature Cell Biology8, 815–825
(10 August 2006); doi:10.1038/ncb1438
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news and views Eph tumour suppression: the dark side of Gleevec
Jean Y. J. Wang Nature Cell Biology8, 785–786
(10 August 2006); doi:10.1038/ncb0806-785
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letter Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase
Hongchuan Jin, Tobias Sperka, Peter Herrlich and Helen Morrison Nature442, 576–579
(02 August 2006); doi:10.1038/nature04856
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July
letter The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
Paul A. C. Cloos, Jesper Christensen, Karl Agger, Alessio Maiolica, Juri Rappsilber, Torben Antal, Klaus H. Hansen and Kristian Helin Nature442, 307–311
(20 July 2006); doi:10.1038/nature04837
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June
letter Smad4 signalling in T cells is required for suppression of gastrointestinal cancer
Byung-Gyu Kim, Cuiling Li, Wenhui Qiao, Mizuko Mamura, Barbara Kasperczak, Miriam Anver, Lawrence Wolfraim, Suntaek Hong, Elizabeth Mushinski, Michael Potter, Seong-Jin Kim, Xin-Yuan Fu, Chuxia Deng and John J. Letterio Nature441, 1015–1019
(22 June 2006); doi:10.1038/nature04846
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review article Metastasis: a question of life or death
Patrick Mehlen and Alain Puisieux Nature Reviews Cancer6, 449–458
(June 2006); doi:10.1038/nrc1886
| Summary | Full Text (HTML / PDF) |
May
letter Identification of a tumour suppressor network opposing nuclear Akt function
Lloyd C. Trotman, Andrea Alimonti, Pier Paolo Scaglioni, Jason A. Koutcher, Carlos Cordon-Cardo and Pier Paolo Pandolfi Nature441, 523–527
(25 May 2006) ; doi:10.1038/nature04809
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review article Is there more to BARD1 than BRCA1?
Irmgard Irminger-Finger and Charles Edward Jefford Nature Reviews Cancer6, 382–391
(May 2006); doi:10.1038/nrc1878
| Summary | Full Text (HTML / PDF) |
letter Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation
Ingvar Ferby, Markus Reschke, Oliver Kudlacek, Pjotr Knyazev, Guido Pantè, Kerstin Amann, Wolfgang Sommergruber, Norbert Kraut, Axel Ullrich, Reinhard Fässler & Rüdiger Klein Nature Medicine12, 568–573
(May 2006) | doi:10.1038/nm1401
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March
letter Oncogenic activity of Cdc6 through repression of the INK4/ARF locus
Susana Gonzalez, Peter Klatt, Sonia Delgado, Esther Conde, Fernando Lopez-Rios, Montserrat Sanchez-Cespedes, Juan Mendez, Francisco Antequera and Manuel Serrano Nature440, 702–706
(30 March 2006); doi:10.1038/nature04585
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review article Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
Megan Cully , Han You, Arnold J. Levine and Tak W. Mak Nature Reviews Cancer6, 184–192
(March 2006); doi:10.1038/nrc1819
| Summary | Full Text (HTML / PDF) |
letter Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse
Shao-Ping Ji, Yun Zhang, Jamie Van Cleemput, Wen Jiang, Mingxia Liao, Lei Li, Qi Wan, Jon R Backstrom and Xia Zhang Nature Medicine12, 324–329
(March 2006); doi:10.1038/nm1349
| First Paragraph | Full Text (HTML/PDF) |
February
review article Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
Stephen B. Baylin and Joyce E. Ohm Nature Reviews Cancer6, 107–116
(February 2006); doi:10.1038/nrc1799
| Summary | Full Text (HTML / PDF) |
January
article Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing
Dolors Ferres-Marco, Irene Gutierrez-Garcia, Diana M. Vallejo, Jorge Bolivar, Francisco J. Gutierrez-Aviño and Maria Dominguez Nature439, 430–436
(26 January 2006); doi:10.1038/nature04376
| Summary | Full Text (HTML / PDF) |
review article KLF4, p21 and context-dependent opposing forces in cancer
Benjamin D. Rowland and Daniel S. Peeper Nature Reviews Cancer6, 11–23
(January 2006); doi:10.1038/nrc1780
| Summary | Full Text (HTML / PDF) |
article The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
Fisun Hamaratoglu, Maria Willecke, Madhuri Kango-Singh, Riitta Nolo, Eric Hyun, Chunyao Tao, Hamed Jafar-Nejad and Georg Halder Nature Cell Biology8, 27–36
(January 2006); doi:10.1038/ncb1339
| Abstract | Full Text (HTML/PDF) |
article Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
Frank Rosenbauer, Bronwyn M Owens, Li Yu, Joseph R Tumang, Ulrich Steidl, Jeffery L Kutok, Linda K Clayton, Katharina Wagner, Marina Scheller, Hiromi Iwasaki, Chunhui Liu, Björn Hackanson, Koichi Akashi, Achim Leutz, Thomas L Rothstein, Christoph Plass and Daniel G Tenen Nature Genetics38, 27–37
(January 2006); doi:10.1038/ng1679
| Abstract | Full Text (HTML/PDF) |
review article The epigenetic progenitor origin of human cancer
Andrew P. Feinberg, Rolf Ohlsson and Steven Henikoff Nature Reviews Genetics7, 21–33
(January 2006); doi:10.1038/nrg1748
| Summary | Full Text (HTML / PDF) |
brief communication Conservation of gene expression signatures between zebrafish and human liver tumors and tumor progression
Siew Hong Lam, Yi Lian Wu, Vinsensius B Vega, Lance D Miller, Jan Spitsbergen, Yan Tong, Huiqing Zhan, Kunde R Govindarajan, Serene Lee, Sinnakarupan Mathavan, Karuturi R Krishna Murthy, Donald R Buhler, Edison T Liu and Zhiyuan Gong Nature Biotechnology24, 73–75
(January 2006); doi:10.1038/nbt1169
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