signaling gateway home
registrationelectronic alerthelpcontact ussite guidesearch
cell signaling update signaling update home updates  news  research library featured articles conferences

Research library: Oncogenes/Tumor suppressors

2008: | July | June | May | April | March | February | January

Other Years: 2005 | 2006 | 2007

article
Genomic stability and tumour suppression by the APC/C cofactor Cdh1
Irene García-Higuera et al.
Nature Cell Biology 10, 802–811
(July 2008); doi:10.1038/ncb1742
| Summary | Full Text (HTML / PDF) |

news and views
Cdh1: a master G0/G1 regulator
Jeffrey R. Skaar & Michele Pagano
Nature Cell Biology 10, 755–757
(July 2008); doi:10.1038/ncb0708-755
| Full Text (HTML / PDF) |

letter
IRF4 addiction in multiple myeloma
Arthur L. Shaffer et al.
Nature 454, 226–231
(10 July 2008); doi:10.1038/nature07064
| Summary | Full Text (HTML / PDF) |

review
Ras oncogenes: split personalities
Antoine E. Karnoub & Robert A. Weinberg
Nature Reviews Molecular Cell Biology 9, 517–531
(July 2008); doi:10.1038/nrm2438
| Summary | Full Text (HTML / PDF) |

review
Living on a break: cellular senescence as a DNA-damage response
Fabrizio d'Adda di Fagagna
Nature Reviews Cancer 8, 512–522
(July 2008); doi:10.1038/nrc2440
| Summary | Full Text (HTML / PDF) |

article
Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR
Melanie Winter et al.
Nature Cell Biology 10, 812–824
(July 2008); doi:10.1038/ncb1743
| Summary | Full Text (HTML / PDF) |

review
MYB function in normal and cancer cells
Robert G. Ramsay & Thomas J. Gonda
Nature Reviews Cancer 8, 523–534
(July 2008); doi:10.1038/nrc2439
| Summary | Full Text (HTML / PDF) |

article
PML targeting eradicates quiescent leukaemia-initiating cells
Keisuke Ito et al.
Nature 453, 1072–1078
(19 June 2008); doi:10.1038/nature07016
| Summary | Full Text (HTML / PDF) |

letter
Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype
Helene R. McMurray et al.
Nature 453, 1112–1116
(19 June 2008); doi:10.1038/nature06973
| Summary | Full Text (HTML / PDF) |

news and views
Cancer: Deconstructing oncogenesis
Ji Luo & Stephen J. Elledge
Nature 453, 995–996
(19 June 2008); doi:10.1038/453995a
| Full Text (HTML / PDF) |

article
Regulation of autophagy by cytoplasmic p53
Ezgi Tasdemir et al.
Nature Cell Biology 10, 676–687
(June 2008); doi:10.1038/ncb1730
| Summary | Full Text (HTML / PDF) |

news and views
p53: The Janus of autophagy?
Beth Levine & John Abrams
Nature Cell Biology 10, 637–639
(June 2008); doi:10.1038/ncb0608-637
| Full Text (HTML / PDF) |

article
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
Xudong Zhao et al.
Nature Cell Biology 10, 643–653
(June 2008); doi:10.1038/ncb1727
| Summary | Full Text (HTML / PDF) |

letter
p53 regulates glucose metabolism through an IKK–NF-κB pathway and inhibits cell transformation
Keiko Kawauchi, Keigo Araki, Kei Tobiume & Nobuyuki Tanaka
Nature Cell Biology 10, 611–618
(May 2008); doi:10.1038/ncb1724
| Summary | Full Text (HTML / PDF) |

letter
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
Kevin M Haigis et al.
Nature Genetics 40, 600–608
(May 2008); doi:10.1038/ng.115
| Summary | Full Text (HTML / PDF) |

analysis
Transcriptional control of human p53-regulated genes
Todd Riley, Eduardo Sontag, Patricia Chen & Arnold Levine
Nature Reviews Molecular Cell Biology 9, 402–412
(May 2008); doi:10.1038/nrm2395
| Summary | Full Text (HTML / PDF) |

letter
BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
Charles G. Mullighan et al.
Nature 453, 110–114
(1 May 2008); doi:10.1038/nature06866
| Summary | Full Text (HTML / PDF) |

review
GATA1-related leukaemias
Ritsuko Shimizu, James Douglas Engel & Masayuki Yamamoto
Nature Reviews Cancer 8, 279–287
(April 2008); doi:10.1038/nrc2348
| Summary | Full Text (HTML / PDF) |

review
The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy
Isabel M. Chu, Ludger Hengst & Joyce M. Slingerland
Nature Reviews Cancer 8, 253–267
(April 2008); doi:10.1038/nrc2347
| Summary | Full Text (HTML / PDF) |

article
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis
Pekka Katajisto et al.
Nature Genetics 40, 455–459
(April 2008); doi:10.1038/ng.98
| Summary | Full Text (HTML / PDF) |

letter
Tumour maintenance is mediated by eNOS
Kian-Huat Lim, Brooke B. Ancrile, David F. Kashatus & Christopher M. Counter
Nature 452, 646–649
(3 April 2008); doi:10.1038/nature06778
| Summary | Full Text (HTML / PDF) |

review
The cancer biomarker problem
Charles L. Sawyers
Nature 452, 548–552
(3 April 2008); doi:10.1038/nature06913
| Summary | Full Text (HTML / PDF) |

review
Translating insights from the cancer genome into clinical practice
Lynda Chin & Joe W. Gray
Nature 452, 553–552
(3 April 2008); doi:10.1038/nature06914
| Summary | Full Text (HTML / PDF) |

review
Enabling personalized cancer medicine through analysis of gene-expression patterns
Laura J. van't Veer & René Bernards
Nature 452, 564–570
(3 April 2008); doi:10.1038/nature06915
| Summary | Full Text (HTML / PDF) |

letter
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400
Arthur P. Young et al.
Nature Cell Biology 10, 361–369
(March 2008); doi:10.1038/ncb1699
| Summary | Full Text (HTML / PDF) |

article
Protein kinase CK2 links extracellular growth factor signaling with the control of p27Kip1 stability in the heart
Ludger Hauck et al.
Nature Medicine 14, 315–324
(March 2008); doi:10.1038/nm1729
| Summary | Full Text (HTML / PDF) |

news and views
The weakness of a big heart
Thomas Force
Nature Medicine 14, 244–245
(March 2008); doi:10.1038/nm0308-244
| Summary | Full Text (HTML / PDF) |

perspective
MYC in mammalian epidermis: how can an oncogene stimulate differentiation?
Fiona M. Watt, Michaela Frye & Salvador Aznar Benitah
Nature Reviews Cancer 8, 234–242
(March 2008); doi:10.1038/nrc2328
| Summary | Full Text (HTML / PDF) |

letter
Resistance to therapy caused by intragenic deletion in BRCA2
Stacey L. Edwards et al.
Nature 451, 1111–1115
(28 February 2008); doi:10.1038/nature06548
| Summary | Full Text (HTML / PDF) |

letter
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
Wataru Sakai et al.
Nature 451, 1116–1120
(28 February 2008); doi:10.1038/nature06633
| Summary | Full Text (HTML / PDF) |

news and views
Cancer: Crossing over to drug resistance
David M. Livingston & Daniel P. Silver
Nature 451, 1066–1067
(28 February 2008); doi:10.1038/4511066a
| Full Text (HTML / PDF) |

letter
The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis
Qihong Huang et al.
Nature Cell Biology 10, 202–210
(February 2008); doi:10.1038/ncb1681
| Summary | Full Text (HTML / PDF) |

review
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
Markus Welcker & Bruce E. Clurman
Nature Reviews Cancer 8, 83–93
(February 2008); doi:10.1038/nrc2290
| Summary | Full Text (HTML / PDF) |

review
The anaplastic lymphoma kinase in the pathogenesis of cancer
Roberto Chiarle, Claudia Voena, Chiara Ambrogio, Roberto Piva & Giorgio Inghirami
Nature Reviews Cancer 8, 11–23
(January 2008); doi:10.1038/nrc2291
| Summary | Full Text (HTML / PDF) |

article
Widespread microRNA repression by Myc contributes to tumorigenesis
Tsung-Cheng Chang et al.
Nature Genetics 40, 43–50
(January 2008); doi:10.1038/ng.2007.30
| Summary | Full Text (HTML / PDF) |

perspective
The emerging landscape of breast cancer susceptibility
Michael R Stratton & Nazneen Rahman
Nature Genetics 40, 17–22
(January 2008); doi:10.1038/ng.2007.53
| Summary | Full Text (HTML / PDF) |

letter
Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair
Lao H Saal et al.
Nature Genetics 40, 102–107
(January 2008); doi:10.1038/ng.2007.39
| Summary | Full Text (HTML / PDF) |

news and views
BRCA1—sowing the seeds crooked in the furrow
William D Foulkes
Nature Genetics 40, 8–9
(January 2008); doi:10.1038/ng0108-8
| Full Text (HTML / PDF) |

letter
Trisomy represses ApcMin-mediated tumours in mouse models of Down's syndrome
Thomas E. Sussan, Annan Yang, Fu Li, Michael C. Ostrowski & Roger H. Reeves
Nature 451, 73–75
(3 January 2008); doi:10.1038/nature06446
| Summary | Full Text (HTML / PDF) |

letter
NUMB controls p53 tumour suppressor activity
Ivan N. Colaluca et al.
Nature 451, 76–80
(3 January 2008); doi:10.1038/nature06412
| Summary | Full Text (HTML / PDF) |

 Nature Publishing Group

HOME | SIGNALING UPDATE | MOLECULE PAGES | DATA CENTER | ABOUT US
registration | e-alert | help | contact us | site guide | search

© 2002-2008 Nature Publishing Group

Privacy Policy