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Research library: Phosphatases
2002: December | November | October | September | August | June | May | April
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review article
Hydrogen peroxide as second messenger in lymphocyte activation
Michael Reth
Nature Immunology 3, 1129–1134
(December 2002); doi:10.1038/ni1202-1129
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brief communication
Activin/TGF-β induce apoptosis through Smad-dependent expression of the lipid phosphatase SHIP
Hector Valderrama-Carvajal, Eftihia Cocolakis, Annie Lacerte, Eun-Hye Lee, Gerald Krystal, Suhad Ali and Jean-Jacques Lebrun
Nature Cell Biology 4, 963–969
(December 2002); doi:10.1038/ncb885
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review article
Dual-specificity phosphatases as targets for antineoplastic agents
Michael A. Lyon, Alexander P. Ducruet, Peter Wipf and John S. Lazo
Nature Reviews Drug Discovery 1, 961–976
(December 2002); doi:10.1038/nrd963
| Summary | Full Text (HTML / PDF) |
review article
The molecular organization of cerebellar long-term depression
Masao Ito
Nature Reviews Neuroscience 3, 896–902
(November 2002); doi:10.1038/nrn962
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letter
A critical role for the protein tyrosine phosphatase receptor type Z in functional recovery from demyelinating lesions
Sheila Harroch, Glaucia C. Furtado, Wolfgang Brueck, Jack Rosenbluth, Juan Lafaille, Moses Chao, Joseph D. Buxbaum and Joseph Schlessinger
Nature Genetics 32, 411–414
(November 2002); doi:10.1038/ng1004
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original paper
Cdk9, a member of the cdc2-like family of kinases, binds to gp130, the receptor of the IL-6 family of cytokines
Giulia De Falco, Luca Maria Neri, Maria De Falco, Cristiana Bellan, Zailin Yu, Antonio De Luca, Lorenzo Leoncini and Antonio Giordano
Oncogene 21, 7464–7470
(24 October 2002); doi:10.1038/sj.onc.1205967
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news and views
Quorum sensing in Vibrio cholerae
Miguel Cámara, Andrea Hardman, Paul Williams and Debra Milton
Nature Genetics 32, 217–218
(October 2002); doi:10.1038/ng1002-217
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article
Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
Niall C. Tebbutt, Andrew S. Giraud, Melissa Inglese, Brendan Jenkins, Paul Waring, Fiona J. Clay, Sina Malki, Barbara M. Alderman, Dianne Grail, Frédéric Hollande, Joan K. Heath and Matthias Ernst
Nature Medicine 8, 1089–1097
(October 2002); doi:10.1038/nm763
| Abstract | Full Text (HTML/PDF) |
news and views
Inflammation intersection: gp130 balances gut irritation and stomach cancer
Timothy C. Wang and James R. Goldenring
Nature Medicine 8, 1080–1082
(October 2002); doi:10.1038/nm1002-1080
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article
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts
Sunao Takeshita, Noriyuki Namba, Jenny J. Zhao, Yebin Jiang, Harry K. Genant, Matthew J. Silva, Michael D. Brodt, Cheryl D. Helgason, Janet Kalesnikoff, Michael J. Rauh, R. Keith Humphries, Gerald Krystal, Steven L. Teitelbaum and F. Patrick Ross
Nature Medicine 8, 943–949
(September 2002); doi:10.1038/nm752
| Abstract | Full Text (HTML/PDF) |
review article
Protein tyrosine phosphatase 1B inhibitors for diabetes
Theodore O. Johnson, Jacques Ermolieff and Michael R. Jirousek
Nature Reviews Drug Discovery 1, 696–709
(September 2002); doi:10.1038/nrd895
| Summary | Full Text (HTML / PDF) |
letters to nature
Protein phosphatase 1 is a molecular constraint on learning and memory
David Genoux, Ursula Haditsch, Marlen Knobloch, Aubin Michalon, Daniel Storm and Isabelle M. Mansuy
Nature 418, 970–975
(29 August 2002); doi:10.1038/nature00928
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news and views
Cognitive neuroscience: The molecules of forgetfulness
Alcino J. Silva and Sheena A. Josselyn
Nature 418, 929–930
(29 August 2002); doi:10.1038/418929a
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review article
Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo
Andrea L. Bauman and John D. Scott
Nature Cell Biology 4, E203
(August 2002); doi:10.1038/ncb0802-e203
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article
Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms
Zheng Xu and Arthur Weiss
Nature Immunology 3, 764–771
(August 2002); doi:10.1038/ni822
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letter
Structure and catalytic mechanism of the E. coli chemotaxis phosphatase CheZ
Rui Zhao, Edward J. Collins, Robert B. Bourret and Ruth E. Silversmith
Nature Structural Biology 9, 570–575
(August 2002); doi:10.1038/nsb816
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news and views
Last, but not least
Philip Matsumura
Nature Structural Biology 9, 563–564
(August 2002); doi:10.1038/nsb0802-563
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letter
Digenic inheritance of severe insulin resistance in a human pedigree
David B. Savage, Maura Agostini, Inês Barroso, Mark Gurnell, Jian'an Luan, Aline Meirhaeghe, Anne-Helen Harding, Gudrun Ihrke, Odelia Rajanayagam, Maria A. Soos, Stella George, Dirk Berger, E. Louise Thomas, Jimmy D. Bell, Karim Meeran, Richard J. Ross, Antonio Vidal-Puig, Nicholas J. Wareham, Stephen O'Rahilly, V. Krishna K. Chatterjee and Alan J. Schafer
Nature Genetics 31, 379–384
(August 2002); doi:10.1038/ng926
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letters to nature
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
Maria Lindskog, Per Svenningsson, Laura Pozzi, Yong Kim, Allen A. Fienberg, James A. Bibb, Bertil B. Fredholm, Angus C. Nairn, Paul Greengard and Gilberto Fisone
Nature 418, 774–778
(15 August 2002); doi:10.1038/nature00817
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news and views
Signal transduction: Positive feedback from coffee
Jean-Marie Vaugeois
Nature 418, 734–736
(15 August 2002); doi:10.1038/418734a
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letters to nature
Modulation of an RNA-binding protein by abscisic-acid-activated protein kinase
Jiaxu Li, Toshinori Kinoshita, Sona Pandey, Carl K.-Y. Ng, Steven P. Gygi, Ken-ichiro Shimazaki and Sarah M. Assmann
Nature 418, 793–797
(15 August 2002); doi:10.1038/nature00936
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letters to nature
Transcriptional co-activator PGC-1a drives the formation of slow-twitch muscle fibres
Jiandie Lin, Hai Wu, Paul T. Tarr, Chen-Yu Zhang, Zhidan Wu, Olivier Boss, Laura F. Michael, Pere Puigserver, Eiji Isotani, Eric N. Olson, Bradford B. Lowell, Rhonda Bassel-Duby and Bruce M. Spiegelman
Nature 418, 797–801
(15 August 2002); doi:10.1038/nature00904
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news and views
Physiology: Muscle regulator goes the distance
Richard Turner
Nature 418, 740
(15 August 2002); doi:10.1038/418740a
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letter
PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster
Daimark Bennett and Luke Alphey
Nature Genetics 31, 419–423
(August 2002); doi:10.1038/ng938
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review article
T-cell signalling and autoimmunity: molecular mechanisms of disease
Pamela S. Ohashi
Nature Reviews Immunology 2, 427–438
(June 2002); doi:10.1038/nri822
| Abstract | Full Text (HTML/PDF) |
news and views
TOUCHINGbase: Chemotaxis a la PTEN
Nature Genetics 31, 231
(July 2002); doi:10.1038/ng0702-231
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brief communication
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23
Jing Li, Ying Yang, Yue Peng, Richard J. Austin, Winfried G. van Eyndhoven, Ken C. Q. Nguyen, Tim Gabriele, Mila E. McCurrach, Jeffrey R. Marks, Timothy Hoey, Scott W. Lowe & Scott Powers
Nature Genetics 31, 133–134
(June 2002); doi:10.1038/ng888
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historical perspective
The origins of protein phosphorylation
Philip Cohen
Nature Cell Biology 4, E127
(May 2002); doi:10.1038/ncb0502-e127
| Abstract | Full Text (HTML/PDF) |
brief communication
Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation
Niels Mailand, Claudia Lukas, Brett K. Kaiser, Peter K. Jackson, Jiri Bartek and Jiri Lukas
Nature Cell Biology 4, 318–322
(April 2002); doi:10.1038/ncb777
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