article Molecular machinery for non-vesicular trafficking of ceramide
Kentaro Hanada, Keigo Kumagai, Satoshi Yasuda, Yukiko Miura, Miyuki Kawano, Masayoshi Fukasawa and Masahiro Nishijima Nature426, 803–809
(18 December 2003); doi:10.1038/nature02188
| Abstract | Full Text (HTML / PDF) |
news and views Cell biology: Earthworms and lipid couriers
Sean Munro Nature426, 775–776
(18 December 2003); doi:10.1038/426775a
| Full Text (HTML / PDF) |
letters to nature Evolutionary conservation of biogenesis of β-barrel membrane proteins
Stefan A. Paschen, Thomas Waizenegger, Tincuta Stan, Marc Preuss, Marek Cyrklaff, Kai Hell, Doron Rapaport and Walter Neupert Nature426, 862–866
(18 December 2003); doi:10.1038/nature02208
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article Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
Marcy A Kingsbury, Stevens K Rehen, James J A Contos, Christine M Higgins and Jerold Chun Nature Neuroscience6, 1292–1299
(December 2003); doi:10.1038/nn1157
| Abstract | Full Text (HTML/PDF) |
article Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis
Darren Boehning, Randen L. Patterson, Leela Sedaghat, Natalia O. Glebova, Tomohiro Kurosaki and Solomon H. Snyder Nature Cell Biology5, 1051–1061
(December 2003); doi:10.1038/ncb1063
| Abstract | Full Text (HTML/PDF) |
news and views Calcium orchestrates apoptosis
Mark P. Mattson and Sic L. Chan Nature Cell Biology5, 1041–1043
(December 2003); doi:10.1038/ncb1203-1041
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November
article Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development
Valérie Pouillon, Romana Hascakova-Bartova, Bernard Pajak, Emmanuelle Adam, Françoise Bex, Valérie Dewaste, Carine Van Lint, Oberdan Leo, Christophe Erneux and Stéphane Schurmans Nature Immunology4, 1136–1143
(November 2003); doi:10.1038/ni980
| Abstract | Full Text (HTML/PDF) |
letter Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis
Moritoshi Sato, Yoshibumi Ueda, Tokio Takagi and Yoshio Umezawa Nature Cell Biology5, 1016–1022
(November 2003); doi:10.1038/ncb1054
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article PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis
Rong Rong, Jee-Yin Ahn, Honglian Huang, Eiichiro Nagata, Daniel Kalman, Judith A Kapp, Jiancheng Tu, Paul F Worley, Solomon H Snyder and Keqiang Ye Nature Neuroscience6, 1153–1161
(November 2003); doi:10.1038/nn1134
| Abstract | Full Text (HTML/PDF) |
September
article Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia
Takuya Matsunaga, Naofumi Takemoto, Tsutomu Sato, Rishu Takimoto, Ikuta Tanaka, Akihito Fujimi, Takehide Akiyama, Hiroyuki Kuroda, Yutaka Kawano, Masayoshi Kobune, Junji Kato, Yasuo Hirayama, Sumio Sakamaki, Kyuhei Kohda, Kensuke Miyake and Yoshiro Niitsu Nature Medicine9, 1158–1165
(September 2003); doi:10.1038/nm909
| Abstract | Full Text (HTML/PDF) |
letter Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells
Michael Beil, Alexandre Micoulet, Götz von Wichert, Stephan Paschke, Paul Walther, M. Bishr Omary, Paul P. Van Veldhoven, Ulrike Gern, Elke Wolff-Hieber, Juliane Eggermann, Johannes Waltenberger, Guido Adler, Joachim Spatz and Thomas Seufferlein Nature Cell Biology5, 803–811
(September 2003); doi:10.1038/ncb1037
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article Retrograde regulation of synaptic vesicle endocytosis and recycling
Kristina D. Micheva, Jo Ann Buchanan, Ronald W. Holz and Stephen J. Smith Nature Neuroscience6, 925–932
(September 2003); doi:10.1038/nn1114
| Abstract | Full Text (HTML/PDF) |
news and views NO going back
Jane Sullivan Nature Neuroscience6, 905–906
(September 2003); doi:10.1038/nn0903-905
| Full Text (HTML/PDF) |
letters to nature Proton-sensing G-protein-coupled receptors
Marie-Gabrielle Ludwig, Miroslava Vanek, Danilo Guerini, Jürg A. Gasser, Carol E. Jones, Uwe Junker, Hans Hofstetter, Romain M. Wolf and Klaus Seuwen Nature425, 93–98
(04 September 2003); doi:10.1038/nature01905
| First Paragraph | Full Text (HTML / PDF) |
August
article Contribution of BCAP to maintenance of mature B cells through c-Rel
Tetsuo Yamazaki and Tomohiro Kurosaki Nature Immunology4, 780–786
(August 2003); doi:10.1038/ni949
| Abstract | Full Text (HTML/PDF) |
review article The emerging role of lysophosphatidic acid in cancer
Gordon B. Mills and Wouter H. Moolenaar Nature Reviews Cancer3, 582–591
(August 2003); doi:10.1038/nrc1143
| Abstract | Full Text (HTML / PDF) |
article Continuous T cell receptor signaling required for synapse maintenance and full effector potential
Johannes B. Huppa, Michael Gleimer, Cenk Sumen and Mark M. Davis Nature Immunology4, 749–755
(August 2003); doi:10.1038/ni951
| Abstract | Full Text (HTML/PDF) |
July
perspectives Timeline: 20 years of Ins(1,4,5)P3, and 40 years before
Robin F. Irvine Nature Reviews Molecular Cell Biology4, 580–585
(July 2003); doi:10.1038/nrm1152
| Abstract | Full Text (HTML / PDF) |
news and views Polyglutamine neurodegeneration: minding your Ps and Qs
Henry Paulson Nature Medicine9, 825–826
(July 2003); doi:10.1038/nm0703-825
| Full Text (HTML/PDF) |
research article Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry
Markus R Wenk, Louise Lucast, Gilbert Di Paolo, Anthony J Romanelli, Sharon F Suchy, Robert L Nussbaum, Gary W Cline, Gerald I Shulman, Walter McMurray and Pietro De Camilli Nature Biotechnology21, 813–817
(July 2003); doi:10.1038/nbt837
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letter Accumulation of anchored proteins forms membrane diffusion barriers during neuronal polarization
Chieko Nakada, Kenneth Ritchie, Yuichi Oba, Mitsuhiro Nakamura, Yoko Hotta, Ryota Iino, Rinshi S. Kasai, Kazuhiko Yamaguchi, Takahiro Fujiwara and Akihiro Kusumi Nature Cell Biology5, 626–632
(July 2003); doi:10.1038/ncb1009
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news and views Neuronal polarization: building fences for molecular segregation
Carlos G. Dotti and Mu-ming Poo Nature Cell Biology5, 591–594
(July 2003); doi:10.1038/ncb0703-591b
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article Deletion of cytosolic phospholipase A2 promotes striated muscle growth
Syed Haq, Heiko Kilter, Ashour Michael, Jingzang Tao, Eileen O'Leary, Xio Ming Sun, Brian Walters, Kausik Bhattacharya, Xin Chen, Lei Cui, Michele Andreucci, Anthony Rosenzweig, J. Luis Guerrero, Richard Patten, Ronglih Liao, Jeffery Molkentin, Michael Picard, Joseph V. Bonventre and Thomas Force Nature Medicine9, 944–951
(July 2003); doi:10.1038/nm891
| Abstract | Full Text (HTML/PDF) |
June
article NKG2D-DAP10 triggers human NK cell-mediated killing via a Syk-independent regulatory pathway
Daniel D Billadeau, Jadee L Upshaw, Renee A Schoon, Christopher J Dick and Paul J Leibson Nature Immunology4, 557–564
(June 2003); doi:10.1038/ni929
| Abstract | Full Text (HTML/PDF) |
article NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases
Simona Zompi, Jessica A Hamerman, Kouetsu Ogasawara, Edina Schweighoffer, Victor L J Tybulewicz, James P Di Santo, Lewis L Lanier and Francesco Colucci Nature Immunology4, 565–572
(June 2003); doi:10.1038/ni930
| Abstract | Full Text (HTML/PDF) |
news and views The choices of a natural killer
Giorgio Trinchieri Nature Immunology4, 509–510
(June 2003); doi:10.1038/ni0603-509
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article A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting
Anja U Bräuer, Nicolai E Savaskan, Hartmut Kühn, Siegfried Prehn, Olaf Ninnemann and Robert Nitsch Nature Neuroscience6, 572–578
(June 2003); doi:10.1038/nn1052
| Abstract | Full Text (HTML/PDF) |
article MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb
Yasuhiko Kawakami, Joaquín Rodríguez-León, Christopher M. Koth, Dirk Büscher, Tohru Itoh, Ángel Raya, Jennifer K. Ng, Concepción Rodríguez Esteban, Shigeru Takahashi, Domingos Henrique, May-Fun Schwarz, Hiroshi Asahara and Juan Carlos Izpisúa Belmonte Nature Cell Biology5, 513–519
(June 2003); doi:10.1038/ncb989
| Abstract | Full Text (HTML/PDF) |
news and views Deconstructing phosphatases in limb development
Andrew T. Dudley and Clifford J. Tabin Nature Cell Biology5, 499–501
(June 2003); doi:10.1038/ncb0603-499
| Full Text (HTML/PDF) |
May
letters to nature Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
Kazutoshi Takahashi, Kaoru Mitsui and Shinya Yamanaka Nature423, 541–545
(29 May 2003); doi:10.1038/nature01646
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brief communication Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disorders
Bethan Jones, Emma L. Jones, Stephanie A. Bonney, Hetal N. Patel, Arjen R. Mensenkamp, Sophie Eichenbaum-Voline, Mats Rudling, Urban Myrdal, Grazia Annesi, Sandhia Naik, Nigel Meadows, Aldo Quattrone, Suhail A. Islam, Rossitza P. Naoumova, Bo Angelin, Recaredo Infante, Emile Levy, Claude C. Roy, Paul S. Freemont, James Scott and Carol C. Shoulders Nature Genetics34, 29–31
(May 2003); doi:10.1038/ng1145
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review article Nuclear lipid signalling
Robin F. Irvine Nature Reviews Molecular Cell Biology4, 349–361
(May 2003); doi:10.1038/nrm1100
| Summary | Full Text (HTML / PDF) |
April
review article The role of PI3K in immune cells
Shigeo Koyasu Nature Immunology4, 313–319
(April 2003); doi:10.1038/ni0403-313
| Abstract | Full Text (HTML/PDF) |
review article PI3K in lymphocyte development, differentiation and activation
Klaus Okkenhaug and Bart Vanhaesebroeck Nature Reviews Immunology3, 317–330
(April 2003); doi:10.1038/nri1056
| Summary | Full Text (HTML / PDF) |
article A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-γ1
Rina Plattner, Brenda J. Irvin, Shuling Guo, Kevin Blackburn, Andrius Kazlauskas, Robert T. Abraham, John D. York and Ann Marie Pendergast Nature Cell Biology5, 309–319
(April 2003); doi:10.1038/ncb949
| Abstract | Full Text (HTML/PDF) |
letter A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome
Mark O'Driscoll, Victor L. Ruiz-Perez, C. Geoffrey Woods, Penny A. Jeggo and Judith A. Goodship Nature Genetics33, 497–501
(April 2003); doi:10.1038/ng1129
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March
article PI3K and Btk differentially regulate B cell antigen receptor-mediated signal transduction
Harumi Suzuki, Satoshi Matsuda, Yasuo Terauchi, Mari Fujiwara, Toshiaki Ohteki, Tomoichiro Asano, Timothy W. Behrens, Taku Kouro, Kiyoshi Takatsu, Takashi Kadowaki and Shigeo Koyasu Nature Immunology4, 280–286
(March 2003); doi:10.1038/ni890
| Abstract | Full Text (HTML/PDF) |
article Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
Amy N. Anzelon, Hong Wu and Robert C. Rickert Nature Immunology4, 287–294
(March 2003); doi:10.1038/ni892
| Abstract | Full Text (HTML/PDF) |
February
article Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
Sean B. Joseph, Antonio Castrillo, Bryan A. Laffitte, David J. Mangelsdorf and Peter Tontonoz Nature Medicine9, 213–219
(February 2003); doi:10.1038/nm820
| Abstract | Full Text (HTML/PDF) |
news and views eLiXiRs for restraining inflammation
Mason W. Freeman and Kathryn J. Moore Nature Medicine9, 168–169
(February 2003); doi:10.1038/nm0203-168
| Full Text (HTML/PDF) |
original paper Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling
Donglei Zhang and Pnina Brodt Oncogene22, 974–982
(20 February 2003); doi:10.1038/sj.onc.1206197
| Abstract |
January
article Serum-derived protein S binds to phosphatidylserine and stimulates
the phagocytosis of apoptotic cells
Howard A. Anderson, Caroline A. Maylock, Joy A. Williams, Cloud P. Paweletz,
Hongjun Shu and Emily Shacter Nature Immunology4, 87–91
(January 2003); doi:10.1038/ni871
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