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Research library: Phospholipid signaling

2004: December | November | October | September | August | July | June | May | April | March | February | January

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letters to nature
Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes
Christian Wolfrum, Esra Asilmaz, Edlira Luca, Jeffrey M. Friedman and Markus Stoffel
Nature 432, 1027–1032
(23 December 2004); doi:10.1038/nature03047
| First Paragraph | Full Text (HTML / PDF) |

article
Prevention of cholesterol gallstone disease by FXR agonists in a mouse model
Antonio Moschetta, Angie L Bookout and David J Mangelsdorf
Nature Medicine 10, 1352–1358
(December 2004); doi:10.1038/nm1138
| Abstract | Full Text (HTML/PDF) |

news and views
Chipping away at gallstones
Kerry B Goralski and Christopher J Sinal
Nature Medicine 10, 1301–1302
(December 2004); doi:10.1038/nm1204-1301
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article
Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin
Kara S Giddings, Ji Zhao, Peter J Sims and Rodney K Tweten
Nature Structural and Molecular Biology 11, 1173–1178
(December 2004); doi:10.1038/nsmb862
| Abstract | Full Text (HTML/PDF) |

news and views
A bacterial big-MAC attack
Ioan Iacovache and F Gisou van der Goot
Nature Structural and Molecular Biology 11, 1163–1164
(December 2004); doi:10.1038/nsmb1204-1163
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review article
Subversion of phosphoinositide metabolism by intracellular bacterial pathogens
Javier Pizarro-Cerdá and Pascale Cossart
Nature Cell Biology 6, 1026–1033
(November 2004); doi:10.1038/ncb1104-1026
| Abstract | Full Text (HTML/PDF) |

letter
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-δ deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy
Lihong Cheng, Guoliang Ding, Qianhong Qin, Yao Huang, William Lewis, Nu He, Ronald M Evans, Michael D Schneider, Florence A Brako, Yan Xiao, Yuqing E Chen and Qinglin Yang
Nature Medicine 10, 1245–1250
(November 2004); doi:10.1038/nm1116
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article
Regulation of Bin1 SH3 domain binding by phosphoinositides
Chie Kojima, Ari Hashimoto, Izumi Yabuta, Mayumi Hirose, Shigeru Hashimoto, Yasunori Kanaho, Hideki Sumimoto, Takahisa Ikegami and Hisataka Sabe
The EMBO Journal 23, 4413–4422
(November 2004); doi:10.1038/sj.emboj.7600442
| Abstract | Full Text (HTML/PDF) |

news and views
Opening the GAP
Michelle Montoya
Nature Structural and Molecular Biology 11, 1033
(November 2004); doi:10.1038/nsmb1104-1033
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article
Rolling blackout, a newly identified PIP2-DAG pathway lipase required for Drosophila phototransduction
Fu-De Huang, Heinrich J G Matthies, Sean D Speese, Mark A Smith and Kendal Broadie
Nature Neuroscience 7, 1070–1078
(October 2004); doi:10.1038/nn1313
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news and views
Crossing the tracks
Jon Reynolds
Nature Cell Biology 6, 915
(October 2004); doi:10.1038/ncb1004-915
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article
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking
Gilbert Di Paolo, Howard S. Moskowitz, Keith Gipson, Markus R. Wenk, Sergey Voronov, Masanori Obayashi, Richard Flavell, Reiko M. Fitzsimonds, Timothy A. Ryan and Pietro De Camilli
Nature 431, 415–422
(23 September 2004); doi:10.1038/nature02896
| Abstract | Full Text (HTML / PDF) |

letters to nature
A microtubule-binding myosin required for nuclear anchoring and spindle assembly
Kari L. Weber, Anna M. Sokac , Jonathan S. Berg, Richard E. Cheney and William M. Bement
Nature 431, 325–329
(16 September 2004); doi:10.1038/nature02834
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news and views
Cell biology: Myosins meet microtubules
Margaret A. Titus
Nature 431, 252–253
(16 September 2004); doi:10.1038/431252a
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article
PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane
Patricia Viard, Adrian J Butcher, Guillaume Halet, Anthony Davies, Bernd Nürnberg, Fay Heblich and Annette C Dolphin
Nature Neuroscience 7, 939–946
(September 2004); doi:10.1038/nn1300
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article
Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton
Anjon Audhya, Robbie Loewith, Ainslie B Parsons, Lu Gao, Mitsuaki Tabuchi1, Huilin Zhou, Charles Boone, Michael N Hall and Scott D Emr
The EMBO Journal Advanced Online Publication
(September 2004); doi:10.1038/sj.emboj.7600384
| Abstract | Full Text (HTML/PDF) |

review article
Cell signalling and the control of pre-mRNA splicing
Chanseok Shin and James L. Manley
Nature Reviews Molecular Cell Biology 5, 727–738
(September 2004); doi:10.1038/nrm1467
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article
Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4
Han Dai, Ok-Ho Shin, Mischa Machius, Diana R Tomchick, Thomas C Südhof and Josep Rizo
Nature Structural and Molecular Biology 11, 844–849
(September 2004); doi:10.1038/nsmb817
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news and views
Cell biology: Regulated self–cannibalism
Daniel J. Klionsky
Nature 431, 31–32
(02 September 2004); doi:10.1038/431031a
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review article
Cytoskeletal regulation: rich in lipids
Paul A. Janmey and Uno Lindberg
Nature Reviews Molecular Cell Biology 5, 658–666
(August 2004); doi:10.1038/nrm1434
| Summary | Full Text (HTML / PDF) |

article
Rapid vesicular translocation and insertion of TRP channels
Vassilios J. Bezzerides, I. Scott Ramsey, Suhas Kotecha, Anna Greka and David E. Clapham
Nature Cell Biology 6, 709–720
(August 2004); doi:10.1038/ncb1150
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news and views
Exciting trips for TRPs
Craig Montell
Nature Cell Biology 6, 690–692
(August 2004); doi:10.1038/ncb0804-690
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review article
Hyaluronan: from extracellular glue to pericellular cue
Bryan P. Toole
Nature Reviews Cancer 4, 528–539
(July 2004); doi:10.1038/nrc1391
| Abstract | Full Text (HTML / PDF) |

article
Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun and Hiroshi Ueda
Nature Medicine 10, 712–718
(July 2004); doi:10.1038/nm1060
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news and views
Balancing muscle hypertrophy and atrophy
Eric P Hoffman and Gustavo A Nader
Nature Medicine 10, 584–585
(June 2004); doi:10.1038/nm0604-584
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letter
Memo mediates ErbB2-driven cell motility
Romina Marone, Daniel Hess, David Dankort, William J. Muller, Nancy E. Hynes and Ali Badache
Nature Cell Biology 6, 515–522
(June 2004); doi:10.1038/ncb1134
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review article
PI-loting membrane traffic
Maria Antonietta De Matteis and Anna Godi
Nature Cell Biology 6, 487–492
(June 2004); doi:10.1038/ncb0604-487
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article
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
Pradip K Majumder, Phillip G Febbo, Rachel Bikoff, Raanan Berger, Qi Xue, Louis M McMahon, Judith Manola, James Brugarolas, Timothy J McDonnell, Todd R Golub, Massimo Loda, Heidi A Lane and William R Sellers
Nature Medicine 10, 594–601
(June 2004); doi:10.1038/nm1052
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news and views
TORward AKTually useful mouse models
Ingo K Mellinghoff and Charles L Sawyers
Nature Medicine 10, 579–580
(June 2004); doi:10.1038/nm0604-579
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article
FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P
Anna Godi, Antonella Di Campli, Athanasios Konstantakopoulos, Giuseppe Di Tullio, Dario R. Alessi, Gursant S. Kular, Tiziana Daniele, Pierfrancesco Marra, John M. Lucocq and M. Antonietta De Matteis
Nature Cell Biology 6, 393–404
(May 2004); doi:10.1038/ncb1119
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news and views
New candidates for vesicle coat proteins
Michael Roth
Nature Cell Biology 6, 384–385
(May 2004); doi:10.1038/ncb0504-384
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letter
PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia
Tsukasa Oikawa, Hideki Yamaguchi, Toshiki Itoh, Masayoshi Kato, Takeshi Ijuin, Daisuke Yamazaki, Shiro Suetsugu and Tadaomi Takenawa
Nature Cell Biology 6, 420–426
(May 2004); doi:10.1038/ncb1125
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article
The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development
Heather J Hinton, Dario R Alessi and Doreen A Cantrell
Nature Immunology 5, 539–545
(May 2004); doi:10.1038/ni1062
| Abstract | Full Text (HTML/PDF) |

news and views
Membrane trafficking: Dual-key strategy
Toshiki Itoh and Pietro De Camilli
Nature 429, 141–143
(13 May 2004); doi:10.1038/429141a
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article
Delivery of raft-associated, GPI-anchored proteins to the apical surface of polarized MDCK cells by a transcytotic pathway
Roman Polishchuk, Alessio Di Pentima and Jennifer Lippincott-Schwartz
Nature Cell Biology 6, 297–307
(April 2004); doi:10.1038/ncb1109
| Abstract | Full Text (HTML/PDF) |

news and views
Unravelling protein sorting
W. James Nelson and Enrique Rodriguez-Boulan
Nature Cell Biology 6, 282–284
(April 2004); doi:10.1038/ncb0404-282
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research article
The plasma membrane-bound phospholipase Dd enhances freezing tolerance in Arabidopsis thaliana
Weiqi Li, Maoyin Li, Wenhua Zhang, Ruth Welti and Xuemin Wang
Nature Biotechnology 22, 427–433
(April 2004); doi:10.1038/nbt949
| Abstract | Full Text (HTML/PDF) |

letter
PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3
Ingrid Remy, Annie Montmarquette and Stephen W. Michnick
Nature Cell Biology 6, 358–365
(April 2004); doi:10.1038/ncb1113
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letter
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis
Andrew R. Conery, Yanna Cao, E. Aubrey Thompson, Courtney M. Townsend, Jr Tien C. Ko and Kunxin Luo
Nature Cell Biology 6, 366–372
(April 2004); doi:10.1038/ncb1117
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article
CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer
Zhongmin Guo, Jürgen F. Linn, Guojun Wu, Sarah L Anzick, Claus F Eisenberger, Sarel Halachmi, Yoram Cohen, Alexey Fomenkov, Mohammad Obaidul Hoque, Kenji Okami, Gabriel Steiner, James M Engles, Motonabu Osada, Chulso Moon, Edward Ratovitski, Jeffrey M Trent, Paul S Meltzer, William H Westra, Lambertus A Kiemeney, Mark P Schoenberg, David Sidransky and Barry Trink
Nature Medicine 10, 374–381
(April 2004); doi:10.1038/nm1010
| Abstract | Full Text (HTML/PDF) |

letter
SREBPs suppress IRS-2-mediated insulin signalling in the liver
Tomohiro Ide, Hitoshi Shimano, Naoya Yahagi, Takashi Matsuzaka, Masanori Nakakuki, Takashi Yamamoto, Yoshimi Nakagawa, Akimitsu Takahashi, Hiroaki Suzuki, Hirohito Sone, Hideo Toyoshima, Akiyoshi Fukamizu and Nobuhiro Yamada
Nature Cell Biology 6, 351–357
(April 2004); doi:10.1038/ncb1111
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letter
Lipid raft proteins have a random distribution during localized activation of the T-cell receptor
Oleg O. Glebov and Benjamin J. Nichols
Nature Cell Biology 6, 238–243
(March 2004); doi:10.1038/ncb1103
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news and views
To cluster or not to cluster: FRETting over rafts
Susan K. Pierce
Nature Cell Biology 6, 180–181
(March 2004); doi:10.1038/ncb0304-180
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article
Therapeutic effects of lysophosphatidylcholine in experimental sepsis
Ji-Jing Yan, Jun-Sub Jung, Jung-Eun Lee, Jongho Lee, Sung-Oh Huh, Hee-Sung Kim, Kyeong Cheon Jung, Jae-Young Cho, Ju-Suk Nam, Hong-Won Suh, Yung-Hi Kim and Dong-Keun Song
Nature Medicine 10, 161–167
(February 2004); doi:10.1038/nm989
| Abstract | Full Text (HTML/PDF) |

news and views
Lipid unites disparate syndromes of sepsis
Haichao Wang, Christopher J Czura and Kevin J Tracey
Nature Medicine 10, 124–125
(February 2004); doi:10.1038/nm0204-124
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review article
Sorting GPI-anchored proteins
Satyajit Mayor and Howard Riezman
Nature Reviews Molecular Cell Biology 5, 110–120
(February 2004); doi:10.1038/nrm1309
| Abstract | Full Text (HTML / PDF) |

letter
An NDPase links ADAM protease glycosylation with organ morphogenesis in C. elegans
Kiyoji Nishiwaki, Yukihiko Kubota, Yuko Chigira, Samir Kumar Roy, Maho Suzuki, Mara Schvarzstein, Yoshifumi Jigami, Naoki Hisamoto and Kunihiro Matsumoto
Nature Cell Biology 6, 31–37
(January 2004); doi:10.1038/ncb1079
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news and views
Sweet control of cell migration, cytokinesis and organogenesis
Benjamin Podbilewicz
Nature Cell Biology 6, 9–11
(January 2004); doi:10.1038/ncb0104-9
| Full Text (HTML/PDF) |

article
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane
Jihong Bai, Ward C Tucker & Edwin R Chapman
Nature Structural & Molecular Biology 11, 36–44
(January 2004); doi:10.1038/nsmb709
| Abstract | Full Text (HTML/PDF) |

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