Research library: Lipid signaling

2007: December | November | October | September | July | May | April | March | February

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December

review
Regulation of ion transport proteins by membrane phosphoinositides
Nikita Gamper & Mark S. Shapiro
Nature Reviews Neuroscience 8, 921–934
(December 2007); doi:10.1038/nrn2257
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November

letter
BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
Daeho Park et al.
Nature 450, 430–434
(15 November 2007); doi:10.1038/nature06329
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letter
Identification of Tim4 as a phosphatidylserine receptor
Masanori Miyanishi, Kazutoshi Tada, Masato Koike, Yasuo Uchiyama, Toshio Kitamura & Shigekazu Nagata
Nature 450, 435–439
(15 November 2007); doi:10.1038/nature06307
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letter
An essential role for a CD36-related receptor in pheromone detection in Drosophila
Richard Benton, Kirsten S. Vannice & Leslie B. Vosshall
Nature 450, 289–293
(8 November 2007); doi:10.1038/nature06328
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scientific report
Rapid ligand-regulated gating kinetics of single inositol 1,4,5-trisphosphate receptor Ca²⁺ release channels
Don-On Daniel Mak, John E Pearson, King Pan Campion Loong, Suman Datta, Marisabel Fernández-Mongil & J Kevin Foskett
EMBO Reports 8, 1044–1051
(November 2007); doi:10.1038/sj.embor.7401087
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October

article
Synaptotagmin activates membrane fusion through a Ca²⁺-dependent trans interaction with phospholipids
Alexander Stein, Anand Radhakrishnan, Dietmar Riedel, Dirk Fasshauer & Reinhard Jahn
Nature Structural & Molecular Biology 14, 904–911
(October 2007); doi:10.1038/nsmb1305
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article
Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance
Takashi Matsuzaka, Hitoshi Shimano, Naoya Yahagi, Toyonori Kato, Ayaka Atsumi, Takashi Yamamoto, Noriyuki Inoue, Mayumi Ishikawa, Sumiyo Okada, Naomi Ishigaki, Hitoshi Iwasaki, Yuko Iwasaki, Tadayoshi Karasawa, Shin Kumadaki, Toshiyuki Matsui, Motohiro Sekiya, Ken Ohashi, Alyssa H Hasty, Yoshimi Nakagawa, Akimitsu Takahashi, Hiroaki Suzuki, Sigeru Yatoh, Hirohito Sone, Hideo Toyoshima, Jun-ichi Osuga & Nobuhiro Yamada
Nature Medicine 13, 1193–1202
(October 2007); doi:10.1038/nm1662
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news and views
It's what you do with the fat that matters!
Clinton R Bruce & Mark A Febbraio
Nature Medicine 13, 1137–1138
(October 2007); doi:10.1038/nm1007-1137
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article
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins, Govind Bhagat, Archana M Agarwal, Giuseppe Basso, Mireia Castillo, Satoru Nagase, Carlos Cordon-Cardo, Ramon Parsons, Juan Carlos Zúñiga-Pflücker, Maria Dominguez & Adolfo A Ferrando
Nature Medicine 13, 1203–1210
(October 2007); doi:10.1038/nm1636
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review
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
Javier A. Menendez & Ruth Lupu
Nature Reviews Cancer 7, 763–777
(October 2007); doi:10.1038/nrc2222
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review
A neuroscientist's guide to lipidomics
Daniele Piomelli, Giuseppe Astarita & Rao Rapaka
Nature Reviews Neuroscience 8, 743–754
(October 2007); doi:10.1038/nrn2233
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September

article
Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype
Eugene A Podrez, Tatiana V Byzova, Maria Febbraio, Robert G Salomon, Yi Ma, Manojkumar Valiyaveettil, Eugenia Poliakov, Mingjiang Sun, Paula J Finton, Brian R Curtis, Juhua Chen, Renliang Zhang, Roy L Silverstein & Stanley L Hazen
Nature Medicine 13, 1086–1095
(2007); doi:10.1038/nm1626
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news and views
The clot thickens-oxidized lipids and thrombosis
Shaun P Jackson & Anna C Calkin
Nature Medicine 13, 1015–1016
(2007); doi:10.1038/nm0907-1015
| Full Text (HTML / PDF) |

article
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide
Giovanni D'Angelo, Elena Polishchuk, Giuseppe Di Tullio, Michele Santoro, Antonella Di Campli, Anna Godi, Gun West, Jacek Bielawski, Chia-Chen Chuang, Aarnoud C. van der Spoel, Frances M. Platt, Yusuf A. Hannun, Roman Polishchuk, Peter Mattjus & Maria Antonietta De Matteis
Nature 449, 62–67
(6 September 2007); doi:10.1038/nature06097
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news and views
Cell biology: Taxi service for lipids
Anthony H. Futerman
Nature 449, 35–37
(6 September 2007); doi:10.1038/449035a
| Full Text (HTML / PDF) |

July

article
A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum
Hidde L. Ploegh
Nature 448, 435–438
(26 July 2007); doi:10.1038/nature06004
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article
IgE^b immune complexes activate macrophages through FcγRIV binding
Masayuki Hirano, Randall S Davis, W David Fine, Shugo Nakamura, Kentaro Shimizu, Hirokazu Yagi, Koichi Kato, Robert P Stephan & Max D Cooper
Nature Immunology 8, 762–771
(July 2007); doi:10.1038/ni1477
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letter
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J
Clement Y. Chow, Yanling Zhang, James J. Dowling, Natsuko Jin, Maja Adamska, Kensuke Shiga, Kinga Szigeti, Michael E. Shy, Jun Li, Xuebao Zhang, James R. Lupski, Lois S. Weisman & Miriam H. Meisler
Nature 448, 68–72
(5 July 2007); doi:10.1038/nature05876
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May

article
Production of Ins(1,3,4,5)P₄ mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation
Andrew T Miller, Mark Sandberg, Yina H Huang, Michael Young, Susan Sutton, Karsten Sauer & Michael P Cooke
Nature Immunology 8, 514–521
(May 2007); doi:10.1038/ni1458
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April

review
Antagonism of the prostaglandin D₂ receptors DP₁ and CRTH2 as an approach to treat allergic diseases
Roy Pettipher, Trevor T. Hansel & Richard Armer
Nature Reviews Drug Discovery 6, 313–325
(April 2007); doi:10.1038/nrd2266
| Summary | Full Text (HTML / PDF) |

review
Potential therapeutic applications of autophagy
David C. Rubinsztein, Jason E. Gestwicki, Leon O. Murphy & Daniel J. Klionsky
Nature Reviews Drug Discovery 6, 304–312
(April 2007); doi:10.1038/nrd2272
| Summary | Full Text (HTML / PDF) |

review
Protein kinase C and other diacylglycerol effectors in cancer
Erin M. Griner & Marcelo G. Kazanietz
Nature Reviews Cancer 7, 281–294
(April 2007); doi:10.1038/nrc2110
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article
Unitary permeability of gap junction channels to second messengers measured by FRET microscopy
Victor H Hernandez, Mario Bortolozzi, Vanessa Pertegato, Martina Beltramello, Michele Giarin, Manuela Zaccolo, Sergio Pantano & Fabio Mammano
Nature Methods 4, 353–358
(April 2007); doi:10.1038/nmeth1031
| Summary | Full Text (HTML / PDF) |

March

review
PI3Kδ and PI3Kγ: partners in crime in inflammation in rheumatoid arthritis and beyond?
Christian Rommel, Montserrat Camps and Hong Ji
Nature Reviews Immunology 7, 191–201
(March 2007); doi:10.1038/nri2036
| Summary | Full Text (HTML / PDF) |

February

letter
Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2
Giulietta Spudich, Margarita V. Chibalina, Josephine Sui-Yan Au, Susan D. Arden, Folma Buss & John Kendrick-Jones
Nature Cell Biology 9, 176–183
(February 2007); doi:10.1038/ncb1531
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