Research library: Proteolysis
2002:December | November
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December
article
An IFN-γ-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
Tomo Saric, Shih-Chung Chang, Akira Hattori, Ian A. York, Shirley Markant, Kenneth L. Rock, Masafumi Tsujimoto and Alfred L. Goldberg
Nature Immunology 3, 1169–1176
(December 2002); doi:10.1038/ni859
| Abstract | Full Text (HTML/PDF) |
article
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
Ian A. York, Shih-Chung Chang, Tomo Saric, Jennifer A. Keys, Janice M. Favreau, Alfred L. Goldberg and Kenneth L. Rock
Nature Immunology 3, 1177–1184
(December 2002); doi:10.1038/ni860
| Abstract | Full Text (HTML/PDF) |
news and views
The final cut: how ERAP1 trims MHC ligands to size
Kirsten Falk and Olaf Rötzschke
Nature Immunology 3, 1121–1122
(December 2002); doi:10.1038/ni1202-1121
| Full Text (HTML/PDF) |
letters to nature
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime
Hyuk Wan Ko, Jin Jiang and Isaac Edery
Nature AOP published online 20 November 2002; doi:10.1038/nature01272
| First Paragraph | Full Text (HTML / PDF) |
meeting report
Ubiquitin branches out
Erica S. Johnson
Nature Cell Biology 4, E295
(December 2002); doi:10.1038/ncb1202-e295
| Full Text (HTML/PDF) |
review article
uPAR: a versatile signalling orchestrator
Francesco Blasi and Peter Carmeliet
Nature Reviews Molecular Cell Biology 3, 932–943
(December 2002); doi:10.1038/nrm977
| Summary | Full Text (HTML / PDF) |
November
article
Direct coupling of the cell cycle and cell death machinery by E2F
Zaher Nahle, Julia Polakoff, Ramana V. Davuluri, Mila E. McCurrach, Matthew D. Jacobson, Masashi Narita, Michael Q. Zhang, Yuri Lazebnik, Dafna Bar-Sagi and Scott W. Lowe
Nature Cell Biology 4, 859–864
(November 2002); doi:10.1038/ncb868
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article
The Doc1 subunit is a processivity factor for the anaphase-promoting complex
Christopher W. Carroll and David O. Morgan
Nature Cell Biology 4, 880–887
(November 2002); doi:10.1038/ncb871
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article
Thymocyte expression of cathepsin L is essential for NKT cell development
Karen Honey, Kamel Benlagha, Courtney Beers, Katherine Forbush, Luc Teyton, Monique J. Kleijmeer, Alexander Y. Rudensky and Albert Bendelac
Nature Immunology 3, 1069–1074
(November 2002); doi:10.1038/ni844
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letters to nature
The F-box protein Slimb controls the levels of clock proteins Period and Timeless
Brigitte Grima, Annie Lamouroux, Elisabeth Chélot, Christian Papin, Bernadette Limbourg-Bouchon and François Rouyer
Nature 420, 178–182
(14 November 2002); doi:10.1038/nature01122
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letters to nature
Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans
Popi Syntichaki, Keli Xu, Monica Driscoll and Nektarios Tavernarakis
Nature 419, 939–944
(31 October 2002); doi:10.1038/nature01108
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October
letters to nature
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
Vanessa S. Marsden, Liam O'Connor, Lorraine A. O'Reilly, John Silke, Donald Metcalf, Paul G. Ekert, David C. S. Huang, Francesco Cecconi, Keisuke Kuida, Kevin J. Tomaselli, Sophie Roy, Don W. Nicholson, David L. Vaux, Philippe Bouillet, Jerry M. Adams and Andreas Strasser
Nature 419, 634–637
(10 October 2002); doi:10.1038/nature01101
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article
Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb
B. Nelson Chau, Helena Lobo Borges, Tung-Ti Chen, Anja Masselli, Irina C. Hunton and Jean Y. J. Wang
Nature Cell Biology 4, 757–765
(October 2002); doi:10.1038/ncb853
| Abstract | Full Text (HTML/PDF) |
news and views
Two faces of caspase-8
Bryan C. Barnhart and Marcus E. Peter
Nature Immunology 3, 896–898
(October 2002); doi:10.1038/ni1002-896
| Full Text (HTML/PDF) |
original paper
Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain
V Cowling & J Downward
Cell Death and Differentiation 9, 1046–1056
(October 2002); doi:10.1038/sj.cdd.4401065
| Abstract |
September
letters to nature
A cryptic protease couples deubiquitination and degradation by the proteasome
Tingting Yao and Robert E. Cohen
Nature 419, 403–407
(26 September 2002); doi:10.1038/nature01071
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news and views
Cell biology: Unchaining the condemned
Keith D. Wilkinson
Nature 419, 351–353
(26 September 2002); doi:10.1038/419351a
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review article
The bcl2 family: regulators of the cellular life-or-death switch
Suzanne Cory and Jerry M. Adams
Nature Reviews Cancer 2, 647–656
(September 2002); doi:10.1038/nrc883
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review article
g-Secretase-mediated proteolysis in cell-surface-receptor signalling
Mark E. Fortini
Nature Reviews Molecular Cell Biology 3, 673–684
(September 2002); doi:10.1038/nrm910
| Summary | Full Text (HTML / PDF) |
perspectives
Signalling shortcuts: cell-surface receptors in the nucleus?
Alan Wells and Ulrich Marti
Nature Reviews Molecular Cell Biology 3, 697–702
(September 2002); doi:10.1038/nrm905
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article
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
Carsten Hoege, Boris Pfander, George-Lucian Moldovan, George Pyrowolakis and Stefan Jentsch
Nature 419, 135–141
(12 September 2002); doi:10.1038/nature00991
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news and views
DNA repair: Right on target with ubiquitin
Cecile M. Pickart Cellular DNA-repair mechanisms prevent mutations from accumulating, thereby averting defects in cell function. A molecule best known for its role in protein degradation is now shown to have a specific task in DNA repair.
Nature 419, 120–121
(12 September 2002); doi:10.1038/419120a
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letters to nature
SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals
Qi Xie, Hui-Shan Guo, Geza Dallman, Shengyun Fang, Allan M. Weissman and Nam-Hai Chua
Nature 419, 167–170
(12 September 2002); doi:10.1038/nature00998
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brief communication
Proteasome subunit Rpn1 binds ubiquitin-like protein domains
Suzanne Elsasser, Rayappa R. Gali, Martin Schwickart, Christopher N. Larsen, David S. Leggett, Britta Müller, Matthew T. Feng, Fabian Tübing, Gunnar A.G. Dittmar and Daniel Finley
Nature Cell Biology 4, 725–730
(September 2002); doi:10.1038/ncb845
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review article
Molecular basis of the VHL hereditary cancer syndrome
William G. Kaelin Jr
Nature Reviews Cancer 2, 673–682
(September 2002); doi:10.1038/nrc885
| Abstract | Full Text (HTML/PDF) |
article
Presenilins are not required for Ab42 production in the early secretory pathway
Christina A. Wilson, Robert W. Doms, Hui Zheng and Virginia M.-Y. Lee
Nature Neuroscience 5, 849–855
(September 2002); doi:10.1038/nn898
| Abstract | Full Text (HTML/PDF) |
original paper
XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis
S B Bratton, J Lewis, M Butterworth, C S Duckett & G M Cohen
Cell Death and Differentiation 9, 881–892
(September 2002); doi:10.1038/sj.cdd.4401069
| Abstract |
August
news and views
'ER we go
Rachel Smallridge
Nature Cell Biology 4, E193
(August 2002); doi:10.1038/ncb0802-e193
| Full Text (HTML/PDF) |
meeting report
Cell cycling? Check your brakes
Steven I. Reed
Nature Cell Biology 4, E199
(August 2002); doi:10.1038/ncb0802-e199
| First Paragraph | Full Text (HTML/PDF) |
letter
APC-dependent proteolysis of the mitotic cyclin Clb2 is essential for mitotic exit
Ralph Wäsch and Frederick R. Cross
Nature 418, 556–562
(1 August 2002); doi:10.1038/nature00856
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news and views
Cell cycle: Oscillation sensation
David O. Morgan and James M. Roberts
Nature 418, 495–496
(1 August 2002); doi:10.1038/418495a
| Full Text (HTML/PDF) |
letter
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
Norihide Yokoi, Kajuro Komeda, He-Yao Wang, Hideki Yano, Kazuhiro Kitada, Yuka Saitoh, Yutaka Seino, Kazuki Yasuda, Tadao Serikawa and Susumu Seino
Nature Genetics 31, 391–394
(August 2002); doi:10.1038/ng927
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July
letters to nature
E3 ubiquitin ligase that recognizes sugar chains
Yukiko Yoshida, Tomoki Chiba, Fuminori Tokunaga, Hiroshi Kawasaki, Kazuhiro Iwai, Toshiaki Suzuki, Yukishige Ito, Koji Matsuoka, Minoru Yoshida, Keiji Tanaka and Tadashi Tai
Nature 418, 438–442
(25 July 2002); doi:10.1038/nature00890
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brief communication
The Vps27p-Hse1p complex binds ubiquitin and mediates endosomal protein sorting
Patricia S. Bilodeau, Jennifer L. Urbanowski, Stanley C. Winistorfer and Robert C. Piper
Nature Cell Biology 4, 534–539
(July 2002); doi:10.1038/ncb815
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review article
Protease degradomics: A new challenge for proteomics
Carlos López-Otín and Christopher M. Overall
Nature Reviews Molecular Cell Biology 3, 509–519
(July 2002); doi:10.1038/nrm858
| Abstract | Full Text (HTML/PDF) |
news and views
Extra Rabs unsnarl a lipid traffic jam
Martin O. Bergo and Stephen G. Young
Nature Medicine 8, 662–664
(July 2002); doi:10.1038/nm0702-662
| Full Text (HTML/PDF) |
June
letter
Structural basis for the recognition of hydroxyproline in HIF-1a by pVHL
Wai-Ching Hon, Michael I. Wilson, Karl Harlos, Timothy D. W. Claridge, Christopher J. Schofield, Christopher W. Pugh, Patrick H. Maxwell, Peter J. Ratcliffe, David I. Stuart and E. Yvonne Jones
Nature 417, 975–978
(27 June 2002); doi:10.1038/nature00767
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letter to nature
Efp targets 14-3-3s for proteolysis and promotes breast tumour growth
Tomohiko Urano, Tomoyuki Saito, Tohru Tsukui, Masayo Fujita, Takayuki Hosoi, Masami Muramatsu, Yasuyoshi Ouchi and Satoshi Inoue
Nature 417, 871–875
(20 June 2002); doi:10.1038/nature00826
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news and views
p53 de-ubiquitination: at the edge between life and death
Paolo Salomoni and Pier Paolo Pandolfi
Nature Cell Biology 4, E152
(June 2002); doi:10.1038/ncb0602-e152
| Full Text (HTML/PDF) |
news and views
The 3D's of apoptosis: death, degradation and DIAPs
Tanapat Palaga and Barbara Osborne
Nature Cell Biology 4, E149
(June 2002); doi:10.1038/ncb0602-e149
| Full Text (HTML/PDF) |
article
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms
Soon Ji Yoo, Jun R. Huh, Israel Muro, Hong Yu, Lijuan Wang, Susan L. Wang, R. M. Renny Feldman, Rollie J. Clem, H.-Arno J. Müller and Bruce A. Hay
Nature Cell Biology 4, 416–424
(June 2002); doi:10.1038/ncb793
| Abstract | Full Text (HTML/PDF) |
article
Morgue mediates apoptosis in the Drosophila melanogaster retina by promoting degradation of DIAP1
Rebecca Hays, Laura Wickline and Ross Cagan
Nature Cell Biology 4, 425–431
(June 2002); doi:10.1038/ncb794
| Abstract | Full Text (HTML/PDF) |
article
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
Hyung Don Ryoo, Andreas Bergmann, Hedva Gonen, Aaron Ciechanover and Hermann Steller
Nature Cell Biology 4, 432–438
(June 2002); doi:10.1038/ncb795
| Abstract | Full Text (HTML/PDF) |
brief communication
Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
Christopher L. Holley, Michael R. Olson, Daniel A. Colón-Ramos and Sally Kornbluth
Nature Cell Biology 4, 439–444
(June 2002); doi:10.1038/ncb798
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brief communication
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis
Rebecca Wilson, Lakshmi Goyal, Mark Ditzel, Anna Zachariou, David A. Baker, Julie Agapite, Hermann Steller and Pascal Meier
Nature Cell Biology 4, 445–450
(June 2002); doi:10.1038/ncb799
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brief communication
Drosophila Morgue is an F box/ubiquitin conjugase domain protein important for grim-reaper mediated apoptosis
John P. Wing, Barbara A. Schreader, Takakazu Yokokura, Yiqin Wang, Paul S. Andrews, Neda Huseinovic, Carolyn K. Dong, Justyne L. Ogdahl, Lawrence M. Schwartz, Kristin White and John R. Nambu
Nature Cell Biology 4, 451–456
(June 2002); doi:10.1038/ncb800
| First Paragraph | Full Text (HTML/PDF) |
brief communication
p53 stability and activity is regulated by Mdm2-mediated induction of alternative p53 translation products
Yili Yin, M. Gloria Luciani and Robin Fåhraeus
Nature Cell Biology 4, 462–467
(June 2002); doi:10.1038/ncb801
| First Paragraph | Full Text (HTML/PDF) |
letter
Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi
Wenyu Li, Srinivasa M. Srinivasula, Jijie Chai, Pingwei Li, Jia-Wei Wu, ZhiJia Zhang, Emad S. Alnemri & Yigong Shi
Nature Structural Biology 9, 436–441
(June 2002); doi:10.1038/nsb795
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news and views
Love it or cleave it: Tough choices in protein quality control
Michael R. Maurizi
Nature Structural Biology 9, 410–412
(June 2002); doi:10.1038/nsb0602-410
| Full Text (HTML/PDF) |
May
letters to nature
HDAC6 is a microtubule-associated deacetylase
Charlotte Hubbert, Amaris Guardiola, Rong Shao, Yoshiharu Kawaguchi, Akihiro Ito, Andrew Nixon, Minoru Yoshida, Xiao-Fan Wang and Tso-Pang Yao
Nature 417, 455–458
(May 2002); doi:10.1038/417455a
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letters to nature
Neutrophil elastase targets virulence factors of enterobacteria
Yvette Weinrauch, Doreen Drujan, Steven D. Shapiro, Jerrold Weiss and Arturo Zychlinsky
Nature 417, 91–94
(May 2002); doi:10.1038/417091a
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article
E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APCCdh1
Jerry Y. Hsu, Julie D.R. Reimann, Claus S. Sørensen, Jiri Lukas and Peter K. Jackson
Nature Cell Biology 4, 358–366
(May 2002); doi:10.1038/ncb785
| Abstract | Full Text (HTML/PDF) |
news and views
Conspiracy to disarm APC in interphase
Hartmut C. Vodermaier and Jan-Michael Peters
Nature Cell Biology 4, E119
(May 2002); doi:10.1038/ncb0502-e119
| Full Text (HTML/PDF) |
letters to nature
Emi1 is required for cytostatic factor arrest in vertebrate eggs
Julie D. R. Reimann and Peter K. Jackson
Nature 416, 850–854
(April 2002); doi:10.1038/416850a
| First Paragraph | Full Text (HTML/PDF) |
brief communication
Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis
Susan C. Shih, David J. Katzmann, Joshua D. Schnell and Myra Sutanto
Nature Cell Biology 4, 389–393
(May 2002); doi:10.1038/ncb790
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commentary
Taking a bite: proteasomal protein processing
Michael Rape and Stefan Jentsch
Nature Cell Biology 4, E113
(May 2002); doi:10.1038/ncb0502-e113
| Full Text (HTML/PDF) |
news and views
Locked but not loaded
Elizabeth H. Cox
Nature Structural Biology 9, 325
(May 2002); doi:10.1038/nsb0502-325
| Full Text (HTML/PDF) |
April
review article
g-SECRETASE, NOTCH, Ab AND ALZHEIMER'S DISEASE: WHERE DO THE PRESENILINS FIT IN?
Sangram S. Sisodia and Peter H. St George-Hyslop
Nature Reviews Neuroscience 3, 281–290
(April 2002); doi:10.1038/nrn785
| Abstract | Full Text (HTML/PDF) |
news and views
A double-edged sword
Valerie Ferrier
Nature Cell Biology 4, E79
(April 2002); doi:10.1038/ncb0402-e79
| Full Text (HTML/PDF) |
article
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
Ning Zheng, Brenda A. Schulman, Langzhou Song, Julie J. Miller, Philip D. Jeffrey, Ping Wang, Claire Chu, Deanna M. Koepp, Stephen J. Elledge, Michele Pagano, Ronald C. Conaway, Joan W. Conaway, J. Wade Harper and Nikola P. Pavletich
Nature 416, 703–709
(April 2002); doi:10.1038/416703a
| Summary | Full Text (HTML/PDF) |
letters to nature
A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal
Y. Amy Lam, T. Glen Lawson, Murugesan Velayutham, Jay L. Zweier and Cecile M. Pickart
Nature 416, 763–767
(April 2002); doi:10.1038/416763a
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letters to nature
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
Muyang Li, Delin Chen, Ariel Shiloh, Jianyuan Luo, Anatoly Y. Nikolaev, Jun Qin and Wei Gu
Nature 416, 648–653
(April 2002); doi:10.1038/nature737
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news and views
Not just research tools—proteasome inhibitors offer therapeutic promise
Alfred L. Goldberg and Kenneth Rock
Nature Medicine 8, 338–340
(April 2002); doi:10.1038/nm0402-338
| Full Text (HTML/PDF) |
news and views
Killed by leukocytes that don't know when to leave
Dean Sheppard
Nature Immunology 3, 337–338
(April 2002); doi:10.1038/ni0402-337
| Full Text (HTML/PDF) |
article
Decreased allergic lung inflammatory cell egression and increased susceptibility to asphyxiation in MMP2-deficiency
David B. Corry, Kirtee Rishi, John Kanellis, Attila Kiss, Li-zhen Song, Jie Xu, Lili Feng, Zena Werb and Farrah Kheradmand
Nature Immunology 3, 347–353
(April 2002); doi:10.1038/ni773
| Abstract | Full Text (HTML/PDF) |
news and views
How calpain is activated by calcium
Ahmad Khorchid and Mitsuhiko Ikura
Nature Structural Biology 9, 239–241
(April 2002); doi:10.1038/nsb0402-239
| Full Text (HTML/PDF) |
letters to nature
Emi1 is required for cytostatic factor arrest in vertebrate eggs
Julie D. R. Reimann and Peter K. Jackson
Nature 416, 850–854
(April 2002); doi:10.1038/416850a
| First Paragraph | Full Text (HTML/PDF) |
news and views
Developmental biology: An arresting activity
Nicholas S. Duesbery and George F. Vande Woude
Nature 416, 804–805
(April 2002); doi:10.1038/416804a
| Full Text (HTML/PDF) |
March
letter
Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type
Steven L. Kazmirski, Rivka L. Isaacson, Chahm An, Ashley Buckle, Christopher M. Johnson, Valerie Daggett and Alan R. Fersht
Nature Structural Biology 9, 112–116
(February 2002); doi:10.1038/nsb745
| First Paragraph | Full Text (HTML/PDF) |
review article
NEW FUNCTIONS FOR THE MATRIX METALLOPROTEINASES IN CANCER PROGRESSION
Mikala Egeblad and Zena Werb
Nature Reviews Cancer 2, 163–176
(March 2002); doi:10.1038/nrc745
| Abstract | Full Text (HTML/PDF) |
article
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
Yasuyuki Fujita, Gerd Krause, Martin Scheffner, Dietmar Zechner, Hugo E. Molina Leddy, Jürgen Behrens and Thomas Sommer and Walter Birchmeier
Nature Cell Biology 4, 222–231
(March 2002); doi:10.1038/ncb758
| Abstract | Full Text (HTML/PDF) |
letters to nature
TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2
Xiaoming Li, Yili Yang and Jonathan D. Ashwell
Nature 416, 345–347
(March 2002); doi:10.1038/416345a
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news and views
Cell biology: The ubiquitin connection
Howard Riezman
Nature 416, 381–383
(March 2002); doi:10.1038/416381a
| Full Text (HTML/PDF) |
letters to nature
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
Simona Polo, Sara Sigismund, Mario Faretta, Monica Guidi, Maria Rosaria Capua, Giovanna Bossi, Hong Chen, Pietro De Camilli and Pier Paolo Di Fiore
Nature 416, 451–455
(March 2002); doi:10.1038/416451a
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February
review article
DEADLY ENCOUNTER: UBIQUITIN MEETS APOPTOSIS
Veronika Jesenberger and Stefan Jentsch
Nature Reviews Molecular Cell Biology 3, 112–121
(February 2002); doi:10.1038/nrm731
| Abstract | Full Text (HTML/PDF) |
news and views
Hip, Hip, Hippi!
Valerie Ferrier
Nature Cell Biology 4, E30
(February 2002); doi:10.1038/ncb0202-e30
| Full Text (HTML/PDF) |
article
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
François G. Gervais, Roshni Singaraja, Steven Xanthoudakis, Claire-Anne Gutekunst, Blair R. Leavitt, Martina Metzler, Abigail S. Hackam, John Tam, John P. Vaillancourt, Vicky Houtzager, Dita M. Rasper, Sophie Roy, Michael R. Hayden and Donald W. Nicholson
Nature Cell Biology 4, 95–105
(February 2002); doi:10.1038/ncb735
| Abstract | Full Text (HTML/PDF) |
news and views
Huntington's disease: Accomplices to neuronal death
Mark P. Mattson
Nature 415, 377–379
(January 2002); doi:10.1038/415377a
| Full Text (HTML/PDF) |
letter
Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type
Steven L. Kazmirski, Rivka L. Isaacson, Chahm An, Ashley Buckle, Christopher M. Johnson, Valerie Daggett and Alan R. Fersht
Nature Structural Biology 9, 112–116
(February 2002); doi:10.1038/nsb745
| First Paragraph | Full Text (HTML/PDF) |
January
article
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
Masanori Asakura, Masafumi Kitakaze, Seiji Takashima, Yulin Liao, Fuminobu Ishikura, Tsuyoshi Yoshinaka, Hiroshi Ohmoto, Koichi Node, Kohichiro Yoshino, Hiroshi Ishiguro, Hiroshi Asanuma, Shoji Sanada, Yasushi Matsumura, Hiroshi Takeda, Shintaro Beppu, Michihiko Tada, Masatsugu Hori and Shigeki Higashiyama
Nature Medicine 8, 35–40
(January 2002); doi:10.1038/nm0102-35
| Abstract | Full Text (HTML/PDF) |
news and views
Shedding growth factors in cardiac hypertrophy
James K. Liao
Nature Medicine 8, 20–21
(January 2002); doi:10.1038/nm0102-20
| Full Text (HTML/PDF) |
review article
Regulatory functions of ubiquitination in the immune system
Y. Ben-Neriah
Nature Immunology 3, 20–26
(January 2002); doi:10.1038/ni0102-20
| Abstract | Full Text (HTML/PDF) |
news and views
Degrading liaisons: Siah structure revealed
John C. Reed and Kathryn R. Ely
Nature Structural Biology 9, 8–10
(January 2002); doi:10.1038/nsb0102-8
| Full Text (HTML/PDF) |
article
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-a signaling
Michael W. Parker and David D. L. Bowtell
Nature Structural Biology 9, 68–75
(January 2002); doi:10.1038/nsb743
| Abstract | Full Text (HTML/PDF) |
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