letter Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination
Lucia Di Marcotullio, Elisabetta Ferretti, Azzura Greco, Enrico De Smaele, Agnese Po, Maria Anna Sico, Maurizio Alimandi, Giuseppe Giannini, Marella Maroder, Isabella Screpanti & Alberto Gulino Nature Cell Biology8, 1415–1423
(December 2006); doi:10.1038/ncb1510
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letter SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination
Moon Hee Lee, Sung Won Lee, Eun Joo Lee, Soo Joon Choi, Sung Soo Chung, Jae Il Lee, Joong Myung Cho, Jae Hong Seol, Sung Hee Baek, Keun Il Kim, Tomoki Chiba, Keiji Tanaka, Ok Sun Bang & Chin Ha Chung Nature Cell Biology8, 1424–1431
(December 2006); doi:10.1038/ncb1512
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letter Bace1 modulates myelination in the central and peripheral nervous system
Xiangyou Hu, Caitlin W Hicks, Wanxia He, Philip Wong, Wendy B Macklin, Bruce D Trapp & Riqiang Yan Nature Neuroscience9, 1520–1525
(December 2006); doi:10.1038/nn1797
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November
letter CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation
Leigh Ann Higa, Min Wu, Tao Ye, Ryuji Kobayashi, Hong Sun & Hui Zhang Nature Cell Biology8, 1277–1283
(November 2006); doi:10.1038/ncb1490
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letter Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination
Jeoung-Sook Shin, Melanie Ebersold, Marc Pypaert, Lelia Delamarre, Adam Hartley and Ira Mellman Nature444 115–118
(02 November 2006); doi:10.1038/nature05261
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article Molecular mechanisms of coupled monoubiquitination
Tanja Woelk, Barbara Oldrini, Elena Maspero, Stefano Confalonieri, Elena Cavallaro, Pier Paolo Di Fiore, & Simona Polo Nature Cell Biology8, 1246–1254
(November 2006); doi:10.1038/ncb1484
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news and views Working out coupled monoubiquitination
Kaisa Haglund & Harald Stenmark Nature Cell Biology8, 1218–1219
(November 2006); doi:10.1038/ncb1106-1218
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October
review Cysteine cathepsins: multifunctional enzymes in cancer
Mona Mostafa Mohamed and Bonnie F. Sloane Nature Reviews Cancer6, 764–775
(October 2006); doi:10.1038/nrc1949
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article Spatially regulated ubiquitin ligation by an ER/nuclear membrane ligase
Min Deng and Mark Hochstrasser Nature443, 827–831
(19 October 2006); doi:10.1038/nature05170
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article Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation
Gustavo J. Gutierrez, Andrea Vögtlin, Ana Castro, Ingvar Ferby, Giorgia Salvagiotto, Ze'ev Ronai, Thierry Lorca & Angel R. Nebreda Nature Cell Biology8, 1084–1094
(2006); doi:10.1038/ncb1472
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review Ubiquitin and ubiquitin-like proteins in cancer pathogenesis
Daniela Hoeller, Christina-Maria Hecker and Ivan Dikic Nature Reviews Cancer6, 776–788
(2006); doi:10.1038/nrc1994
| Summary | Full Text (HTML / PDF) |
letter Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
Shida Yousefi, Remo Perozzo, Inès Schmid, Andrew Ziemiecki, Thomas Schaffner, Leonardo Scapozza, Thomas Brunner & Hans-Uwe Simon Nature Cell Biology8, 1124–1132
(October 2006); doi:10.1038/ncb1482
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news and views Atg5: more than an autophagy factor
Patrice Codogno & Alfred J. Meijer Nature Cell Biology8, 1045–1047
(October 2006); doi:10.1038/ncb1006-1045
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September
letter Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1
Tingting Yao, Ling Song, Wei Xu, George N. DeMartino, Laurence Florens, Selene K. Swanson, Michael P. Washburn, Ronald C. Conaway, Joan Weliky Conaway & Robert E. Cohen Nature Cell Biology8, 994–1002
(September 2006); doi:10.1038/ncb1460
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review The anaphase promoting complex/cyclosome: a machine designed to destroy
Jan-Michael Peters Nature Reviews Molecular Cell Biology7, 644–656
(September 2006); doi:10.1038/nrm1988
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letter Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo
Kip Nalley, Stephen Albert Johnston and Thomas Kodadek Nature442, 1054–1057
(31 August 2006); doi:10.1038/nature05067
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article Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
Masahiro Yamamoto, Toru Okamoto, Kiyoshi Takeda, Shintaro Sato, Hideki Sanjo, Satoshi Uematsu, Tatsuya Saitoh, Naoki Yamamoto, Hiroaki Sakurai, Ken J Ishii, Shoji Yamaoka, Taro Kawai, Yoshiharu Matsuura, Osamu Takeuchi & Shizuo Akirar Nature Immunology7, 962–970
(September 2006); doi:10.1038/ni1367
| Summary | Full Text (HTML / PDF) |
news and views E2 enzymes: expanding the 'ubi-verse' of immune signaling
Averil Ma & Emre Turer Nature Immunology7, 903–904
(September 2006); doi:10.1038/ni0906-903
| Summary | Full Text (HTML / PDF) |
review Divorcing ARF and p53: an unsettled case
Charles J. Sherr Nature Reviews Cancer7, 663–673
(September 2006); doi:10.1038/nrc1954
| Summary | Full Text (HTML / PDF) |
August
letter A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
Lara Fallon, Catherine M.L. Bélanger, Amadou T. Corera, Maria Kontogiannea, Elsa Regan-Klapisz, France Moreau, Jarno Voortman, Michael Haber, Geneviève Rouleau, Thorhildur Thorarinsdottir, Alexis Brice, Paul M.P. van Bergen en Henegouwen & Edward A. Fon Nature Cell Biology8, 834–842
(August 2006); doi:10.1038/ncb1441
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news and views EGFR trafficking: parkin' in a jam
Koraljka Husnjak & Ivan Dikic Nature Cell Biology8, 787–788
(August 2006); doi:10.1038/ncb0806-787
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letter Critical role for Daxx in regulating Mdm2
Jun Tang, Li-Ke Qu, Jianke Zhang, Wenge Wang, Jennifer S. Michaelson, Yan Y. Degenhardt, Wafik S. El-Deiry & Xiaolu Yang Nature Cell Biology8, 855–862
(August 2006); doi:10.1038/ncb1442
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news and views Balancing Mdm2 — a Daxx-HAUSP matter
Ze'ev Ronai Nature Cell Biology8, 790–791
(August 2006); doi:10.1038/ncb0806-790
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article Proteasome-dependent degradation of Est1p regulates the cell cycle–restricted assembly of telomerase in Saccharomyces cerevisiae
Jennifer L Osterhage, Jennell M Talley & Katherine L Friedman Nature Strcutural & Molecular Biology9, 720–728
(10 August 2006); doi:10.1038/nsmb1125
| Summary | Full Text (HTML / PDF) |
letter SPPL2a and SPPL2b promote intramembrane proteolysis of TNFα in activated dendritic cells to trigger IL-12 production
Elena Friedmann, Ehud Hauben, Kerstin Maylandt, Simone Schleeger, Sarah Vreugde, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Daniela Stauffer, Giorgio Rovelli & Bruno Martoglio Nature Cell Biology8, 843–848
(10 August 2006); doi:10.1038/ncb1440
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July
article E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
Cho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim & Dong-Soo Im Nature Medicine12, 809–816
(July 2006); doi:10.1038/nm1440
| Summary | Full Text (HTML / PDF) |
review Neutrophil serine proteases: specific regulators of inflammation
Christine T. N. Pham Nature Reviews Immunology6, 541–550
(July 2006); doi:10.1038/nri1841
| Summary | Full Text (HTML / PDF) |
article E2-EPF UCP targets pVHL for degradation and associates with tumor growth and metastasis
Cho-Rok Jung, Kyung-Sun Hwang, Jinsang Yoo, Won-Kyung Cho, Jin-Man Kim, Woo Ho Kim & Dong-Soo Im Nature Medicine12, 755–762
(02 July 2006); doi:10.1038/nm1440
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June
letter Activity-dependent dynamics and sequestration of proteasomes in dendritic spines
Baris Bingol and Erin M. Schuman Nature441, 1144–1148
(29 June 2006); doi:10.1038/nature04769
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letter Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C
Michelle J. Hayes, Yuu Kimata, Samantha L. Wattam, Catherine Lindon, Guojie Mao, Hiroyuki Yamano & Andrew M. Fry Nature Cell Biology8, 607 - 614
(June 2006); doi:10.1038/ncb1410
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May
review article Regulation of DNA repair by ubiquitylation
Tony T. Huang and Alan D. D'Andrea Nature Reviews Molecular Cell Biology7, 323–334
(May 2006); doi:10.1038/nrm1908
| Summary | Full Text (HTML / PDF) |
letter A ubiquitin–interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome
Karin Flick, Shahri Raasi, Hongwei Zhang, James L. Yen & Peter Kaiser Nature Cell Biology8, 509–515
(May 2006); doi:10.1038/ncb1402
| Summary | Full Text (HTML / PDF) |
review Ubiquitin ligases: cell–cycle control and cancer
Keiichi I. Nakayama and Keiko Nakayama Nature Reviews Cancer6, 369–381
(May 2006); doi:10.1038/nrc1881
| Summary | Full Text (HTML / PDF) |
April
article The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation
Stephane Angers, Chris J. Thorpe, Travis L. Biechele, Seth J. Goldenberg, Ning Zheng, Michael J. MacCoss & Randall T. Moon Nature Cell Biology8, 348–357
(April 2006); doi:10.1038/ncb1381 First Paragraph | Full Text (HTML / PDF) |
letter The reversibility of mitotic exit in vertebrate cells
Tamara A. Potapova, John R. Daum, Bradley D. Pittman, Joanna R. Hudson, Tara N. Jones, David L. Satinover, P. Todd Stukenberg and Gary J. Gorbsky Nature440, 954–958
(13 April 2006); doi:10.1038/nature04652
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article Regulation of monoubiquitinated PCNA by DUB autocleavage
Tony T. Huang, Sebastian M.B. Nijman, Kanchan D. Mirchandani, Paul J. Galardy, Martin A. Cohn, Wilhelm Haas, Steven P. Gygi, Hidde L. Ploegh, René Bernards &: Alan D. D'Andrea Nature Cell Biology8, 341–347
(2006); doi:10.1038/ncb1378
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article NEMO is a sensor of Lys 63-linked polyubiquitination and functions in NF-κB activation
Chuan-Jin Wu, Dietrich B. Conze, Tao Li, Srinivasa M. Srinivasula & Jonathan D. Ashwell Nature Cell Biology80, 398–406
(2006); doi:10.1038/ncb1384
| First Paragraph
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March
letter CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70
Shu-Bing Qian, Holly McDonough, Frank Boellmann, Douglas M. Cyr and Cam Patterson Nature440, 551–555
(23 March 2006); doi:10.1038/nature04600
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article Intracellular trafficking and proteolysis of the Arabidopsis auxin-efflux facilitator PIN2 are involved in root gravitropism
Lindy Abas, René Benjamins, Nenad Malenica, Tomasz Paciorek, Justyna Wiřniewska, Jeanette C. Moulinier-Anzola, Tobias Sieberer, Jiří Friml and Christian Luschnig Nature Cell Biology8, 249–256
(March 2006); doi:10.1038/ncb1369
| Abstract | Full Text (HTML/PDF) |
article Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Sangho Lee, Yien Che Tsai, Rafael Mattera, William J Smith, Michael S Kostelansky, Allan M Weissman, Juan S Bonifacino and James H Hurley Nature Structural and Molecular Biology13, 264–271
(March 2006); doi:10.1038/nsmb1064
| Abstract | Full Text (HTML/PDF) |
article Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Satoshi Hirano, Masato Kawasaki, Hideaki Ura, Ryuichi Kato, Camilla Raiborg, Harald Stenmark and Soichi Wakatsuki Nature Structural and Molecular Biology13, 272–277
(March 2006); doi:10.1038/nsmb1051
| Abstract | Full Text (HTML/PDF) |
news and views U2
Steven L Alam and Wesley I Sundquist Nature Structural and Molecular Biology13, 186–188
(March 2006); doi:10.1038/nsmb0306-186
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February
article V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway
Andrés Hurtado-Lorenzo, Mhairi Skinner, Jaafar El Annan, Masamitsu Futai, Ge-Hong Sun-Wada, Sylvain Bourgoin, James Casanova, Alan Wildeman, Shaliha Bechoua, Dennis A. Ausiello, Dennis Brown and Vladimir Marshansky Nature Cell Biology8, 124–136
(February 2006); doi:10.1038/ncb1348
| Abstract | Full Text (HTML/PDF) |
news and views V-ATPase: a potential pH sensor
Chiara Recchi and Philippe Chavrier Nature Cell Biology8, 107–109
(February 2006); doi:10.1038/ncb0206-107
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letter ClpS is an essential component of the N-end rule pathway in Escherichia coli
A. Erbse, R. Schmidt, T. Bornemann, J. Schneider-Mergener, A. Mogk, R. Zahn, D. A. Dougan and B. Bukau Nature439, 753–756
(09 February 2006); doi:10.1038/nature04412
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letter Regulation of ubiquitin-binding proteins by monoubiquitination
Daniela Hoeller, Nicola Crosetto, Blagoy Blagoev, Camilla Raiborg, Ritva Tikkanen, Sebastian Wagner, Katarzyna Kowanetz, Rainer Breitling, Matthias Mann, Harald Stenmark and Ivan Dikic Nature Cell Biology8, 163–169
(February 2006); doi:10.1038/ncb1354
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article Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
Ashley Mansell, Rosealee Smith, Sarah L Doyle, Pearl Gray, Jennifer E Fenner, Peter J Crack, Sandra E Nicholson, Douglas J Hilton, Luke A J O'Neill and Paul J Hertzog Nature Immunology7, 148–155
(February 2006); doi:10.1038/ni1299
| Abstract | Full Text (HTML/PDF) |
news and views Mal-function of TLRs by SOCS
Takashi Kobayashi, Giichi Takaesu and Akihiko Yoshimura Nature Immunology7, 123–124
(February 2006); doi:10.1038/ni0206-123
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January
article The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
Gianna Elena Hammer, Federico Gonzalez, Marine Champsaur, Dragana Cado and Nilabh Shastri Nature Immunology7, 103–112
(January 2006); doi:10.1038/ni1286
| Abstract | Full Text (HTML/PDF) |
news and views The 'chop-and-change' of MHC class I assembly
Tim Elliott Nature Immunology7, 7–9
(January 2006); doi:10.1038/ni0106-7
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article Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex
Margaret D Myers, Tomasz Sosinowski, Leonard L Dragone, Carmen White, Hamid Band, Hua Gu and Arthur Weiss Nature Immunology7, 57–66
(January 2006); doi:10.1038/ni1291
| Abstract | Full Text (HTML/PDF) |
news and views A SAGA of proteasomal ATPases
Sowmya Swaminathan Nature Cell Biology8, 13
(January 2006); doi:10.1038/ncb0106-13
| Full Text (HTML/PDF) |
