Research library: Proteolysis/Ubiquitination
2007:
December
| November
| October
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2008 | 2009
December
scientific report
Tripeptidyl peptidase II promotes fat formation in a conserved fashion
Renée M McKay, James P McKay, Jae Myoung Suh, Leon Avery & Jonathan M Graff
EMBO Reports 8, 1183–1189
(December 2007); doi:10.1038/sj.embor.7401086
| Summary | Full Text (HTML / PDF) |
article
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites
Maurits F Kleijnen et al.
Nature Structural & Molecular Biology 14, 1180–1188
(December 2007); doi:10.1038/nsmb1335
| Summary | Full Text (HTML / PDF) |
November
letter
AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10
Ho-June Lee et al.
Nature Cell Biology 9, 1303–1310
(November 2007); doi:10.1038/ncb1650
| Summary | Full Text (HTML / PDF) |
review
Finishing mitosis, one step at a time
Matt Sullivan & David O. Morgan
Nature Reviews Molecular Cell Biology 8, 894–903
(November 2007); doi:10.1038/nrm2276
| Summary | Full Text (HTML / PDF) |
perspective
Mechanisms, biology and inhibitors of deubiquitinating enzymes
Kerry Routenberg Love, André Catic, Christian Schlieker and Hidde L Ploegh
Nature Chemical Biology 3, 697–705
(November 2007); doi:10.1038/nchembio.2007.43
| Summary | Full Text (HTML / PDF) |
article
SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress
Yonghua Yang et al.
Nature Cell Biology 9, 1253–1262
(November 2007); doi:10.1038/ncb1645
| Summary | Full Text (HTML / PDF) |
article
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
Hélène Plun-Favreau et al.
Nature Cell Biology 9, 1243–1252
(November 2007); doi:10.1038/ncb1644
| Summary | Full Text (HTML / PDF) |
news and views
HtrA2 and Parkinson's disease: think PINK?
Emad S. Alnemri
Nature Cell Biology 9, 1227–1229
(November 2007); doi:10.1038/ncb1107-1227
| Summary | Full Text (HTML / PDF) |
article
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response
Jantje M Gerdes et al.
Nature Genetics 39, 1350–1360
(November 2007); doi:10.1038/ng.2007.12
| Summary | Full Text (HTML / PDF) |
news and views
A more discerning zinc exporter
Nigel J Robinson
Nature Chemical Biology 3, 692–693
(November 2007); doi:10.1038/nchembio1107-692
| Full Text (HTML / PDF) |
October
letter
Regulation of cell cycle progression and gene expression by H2A deubiquitination
Heui-Yun Joo et al.
Nature 449, 1068–1072
(25 October 2007); doi:10.1038/nature06256
| Summary | Full Text (HTML / PDF) |
letter
Prometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes
Alexandra Reis, Suzanne Madgwick, Heng-Yu Chang, Ibtissem Nabti, Mark Levasseur & Keith T. Jones
Nature Cell Biology 9, 1192–1198
(October 2007); doi:10.1038/ncb1640
| Summary | Full Text (HTML / PDF) |
review
Recent advances in antigen processing and presentation
Peter E Jensen
Nature Immunology 8, 1041–1048
(October 2007); doi:10.1038/ni1516
| Summary | Full Text (HTML / PDF) |
perspective
Emerging roles of proteases in tumour suppression
Carlos López-Otín & Lynn M. Matrisian
Nature Reviews Cancer 7, 800–808
(October 2007); doi:10.1038/nrc2228
| Summary | Full Text (HTML / PDF) |
article
E2–BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages
Devin E Christensen, Peter S Brzovic & Rachel E Klevit
Nature Structural & Molecular Biology 14, 941–948
(October 2007); doi:10.1038/nsmb1295
| Summary | Full Text (HTML / PDF) |
letter
Akt phosphorylation regulates the tumour-suppressor merlin through ubiquitination and degradation
Xiaoling Tang, Sung-Wuk Jang, Xuerong Wang, Zhixue Liu, Scott M. Bahr, Shi-Yong Sun, Daniel Brat, David H. Gutmann & Keqiang Ye
Nature Cell Biology 9, 1199–1207
(October 2007); doi:10.1038/ncb1641
| Summary | Full Text (HTML / PDF) |
article
Noninvasive optical imaging of cysteine protease activity using fluorescently quenched activity-based probes
Galia Blum, Georges von Degenfeld, Milton J Merchant, Helen M Blau & Matthew Bogyo
Nature Chemical Biology 3, 668–677
(October 2007); doi:10.1038/nchembio.2007.26
| Summary | Full Text (HTML / PDF) |
August
article
E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury
Kurt Bachmaier, Sophie Toya, Xiaopei Gao, Thomas Triantafillou, Sean Garrean, Gye Young Park, Randall S Frey, Stephen Vogel, Richard Minshall, John W Christman, Chinnaswamy Tiruppathi & Asrar B Malik
Nature Medicine 13, 920–926
(August 2007); doi:10.1038/nm1607
| Summary | Full Text (HTML / PDF) |
article
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Katarina Wolf, Yi I. Wu, Yueying Liu, Jörg Geiger, Eric Tam, Christopher Overall, M. Sharon Stack & Peter Friedl
Nature Cell Biology 9, 893–904
(August 2007); doi:10.1038/ncb1616
| Summary | Full Text (HTML / PDF) |
perspective
Active-site directed probes to report enzymatic action in the ubiquitin proteasome system
Huib Ovaa
Nature Reviews Cancer 7, 613–620
(August 2007); doi:10.1038/nrc2128
| Summary | Full Text (HTML / PDF) |
article
JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
Bryan Thines, Leron Katsir, Maeli Melotto, Yajie Niu, Ajin Mandaokar, Guanghui Liu, Kinya Nomura, Sheng Yang He, Gregg A. Howe & John Browse
Nature 448, 661–665
(9 August 2007); doi:10.1038/nature05960
| Summary | Full Text (HTML / PDF) |
article
The JAZ family of repressors is the missing link in jasmonate signalling
A. Chini, S. Fonseca, G. Fernández, B. Adie, J. M. Chico, O. Lorenzo, G. García-Casado, I. López-Vidriero, F. M. Lozano, M. R. Ponce, J. L. Micol & R. Solano
Nature 448, 666–671
(9 August 2007); doi:10.1038/nature06006
| Summary | Full Text (HTML / PDF) |
news and views
Plant biology: Jasmonate perception machines
Edward E. Farmer
Nature 448, 659–660
(9 August 2007); doi:10.1038/448659a
| Full Text (HTML / PDF) |
letter
Global changes to the ubiquitin system in Huntington's disease
Eric J. Bennett, Thomas A. Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S. Zaitseva, Christopher H. Becker, Gillian P. Bates, Howard Schulman & Ron R. Kopito
Nature 448, 704–708
(9 August 2007); doi:10.1038/nature06022
| Summary | Full Text (HTML / PDF) |
review
Lysosomes: fusion and function
J. Paul Luzio, Paul R. Pryor & Nicholas A. Bright
Nature Reviews Molecular Cell Biology 8, 622–632
(August 2007); doi:10.1038/nrm2217
| Summary | Full Text (HTML / PDF) |
July
letter
Functional diversification of closely related ARF-GEFs in protein secretion and recycling
Sandra Richter, Niko Geldner, Jarmo Schrader, Hanno Wolters, York-Dieter Stierhof, Gabino Rios, Csaba Koncz, David G. Robinson & Gerd Jürgens
Nature 448, 488–492
(26 July 2007); doi:10.1038/nature05967
| Summary | Full Text (HTML / PDF) |
letter
An ARF-GEF acting at the Golgi and in selective endocytosis in polarized plant cells
Ooi-kock Teh & Ian Moore
Nature 448, 493–496
(26 July 2007); doi:10.1038/nature06023
| Summary | Full Text (HTML / PDF) |
letter
Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility
Hidekazu Iioka, Shun-ichiro Iemura, Tohru Natsume & Noriyuki Kinoshita
Nature Cell Biology 9, 813–821
(July 2007); doi:10.1038/ncb1607
| Summary | Full Text (HTML / PDF) |
article
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
Patrick Ryan Potts & Hongtao Yu
Nature Structural & Molecular Biology 14, 581–590
(July 2007); doi:10.1038/nsmb1259
| Summary | Full Text (HTML / PDF) |
news and views
A SUMO ligase for ALT
Roger R Reddel
Nature Structural & Molecular Biology 14, 570–571
(July 2007); doi:10.1038/nsmb0707-570
| Summary | Full Text (HTML / PDF) |
review
Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla, Kim N. Green & Salvatore Oddo
Nature Reviews Neuroscience 8, 499–509
(July 2007); doi:10.1038/nrn2168
| Summary | Full Text (HTML / PDF) |
June
letter
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging
Jianping Jin, Xue Li, Steven P. Gygi & J. Wade Harper
Nature 447, 1135–1138
(28 June 2007); doi:10.1038/nature05902
| Summary | Full Text (HTML / PDF) |
brief communication
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
Ashley E Sims, Elizabeth Spiteri, Robert J Sims III, Adriana G Arita, Francis P Lach, Thomas Landers, Melanie Wurm, Marcel Freund, Kornelia Neveling, Helmut Hanenberg, Arleen D Auerbach & Tony T Huang
Nature Structural & Molecular Biology 14, 564–567
(June 2007); doi:10.1038/nsmb1252
| Summary | Full Text (HTML / PDF) |
letter
Caspase-14 protects against epidermal UVB photodamage and water loss
Geertrui Denecker, Esther Hoste, Barbara Gilbert, Tino Hochepied, Petra Ovaere, Saskia Lippens, Caroline Van den Broecke, Petra Van Damme, Katharina D'Herde, Jean-Pierre Hachem, Gaetan Borgonie, Richard B. Presland, Luc Schoonjans, Claude Libert, Joël Vandekerckhove, Kris Gevaert, Peter Vandenabeele & Wim Declercq
Nature Cell Biology 9, 666–674
(June 2007); doi:10.1038/ncb1597
| Summary | Full Text (HTML / PDF) |
news and views
Caspase-14 and epidermis maturation
Pierluigi Nicotera & Gerry Melino
Nature Cell Biology 9, 621–622
(June 2007); doi:10.1038/ncb0607-621
| Summary | Full Text (HTML / PDF) |
letter
Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination
Vaniyambadi V. Sridhar, Avnish Kapoor, Kangling Zhang, Jianjun Zhu, Tao Zhou, Paul M. Hasegawa, Ray A. Bressan & Jian-Kang Zhu
Nature 447, 735–738
(7 June 2007); doi:10.1038/nature05864
| Summary | Full Text (HTML / PDF) |
article
PDLIM2-mediated termination of transcription factor NF-κB activation by intranuclear sequestration and degradation of the p65 subunit
Takashi Tanaka, Michael J Grusby & Tsuneyasu Kaisho
Nature Immunology 8, 584–591
(June 2007); doi:10.1038/ni1464
| Summary | Full Text (HTML / PDF) |
May
review
The apoptosome: signalling platform of cell death
Stefan J. Riedl & Guy S. Salvesen
Nature Reviews Molecular Cell Biology 8, 405–413
(May 2007); doi:10.1038/nrm2153
| Summary | Full Text (HTML / PDF) |
April
letter
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
Michaela U. Gack, Young C. Shin, Chul-Hyun Joo, Tomohiko Urano, Chengyu Liang, Lijun Sun, Osamu Takeuchi, Shizuo Akira, Zhijian Chen, Satoshi Inoue & Jae U. Jung
Nature 446, 916–920
(19 April 2007); doi:10.1038/nature05732
| Summary | Full Text (HTML / PDF) |
review
Potential therapeutic applications of autophagy
David C. Rubinsztein, Jason E. Gestwicki, Leon O. Murphy & Daniel J. Klionsky
Nature Reviews Drug Discovery 6, 304–312
(April 2007); doi:10.1038/nrd2272
| Summary | Full Text (HTML / PDF) |
letter
C-terminal modifications regulate MDM2 dissociation and nuclear export of p53
Stephanie Carter, Oliver Bischof, Anne Dejean & Karen H. Vousden
Nature Cell Biology 9, 428–435
(April 2007); doi:10.1038/ncb1562
| Summary | Full Text (HTML / PDF) |
March
letter
Dioxin receptor is a ligand-dependent E3 ubiquitin ligase
Fumiaki Ohtake, Atsushi Baba, Ichiro Takada, Maiko Okada, Kei Iwasaki, Hiromi Miki, Sayuri Takahashi, Alexander Kouzmenko, Keiko Nohara, Tomoki Chiba, Yoshiaki Fujii-Kuriyama & Shigeaki Kato
Nature 446, 562–566
(29 March 2007); doi:10.1038/nature05683
| Summary | Full Text (HTML / PDF) |
letter
Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2
Laëtitia K. Linares, Rosemary Kiernan, Robinson Triboulet, Christine Chable-Bessia, Daniel Latreille, Olivier Cuvier, Matthieu Lacroix, Laurent Le Cam, Olivier Coux & Monsef Benkirane
Nature Cell Biology 9, 331–338
(March 2007); doi:10.1038/ncb1545
| Summary | Full Text (HTML / PDF) |
review
In search of partners: linking extracellular proteases to substrates
Christopher M. Overall and Carl P. Blobel
Nature Reviews Molecular Cell Biology 8, 245–257
(March 2007); doi:10.1038/nrm2120
| Summary | Full Text (HTML / PDF) |
letter
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate
Wei Li, Daqi Tu, Axel T. Brunger and Yihong Ye
Nature 446, 333–337
(15 March 2007); doi:10.1038/nature05542
| Summary | Full Text (HTML / PDF) |
review
Matrix metalloproteinases and the regulation of tissue remodelling
Andrea Page-McCaw, Andrew J. Ewald and Zena Werb
Nature Reviews Molecular Cell Biology 8, 221–223
(March 2007); doi:10.1038/nrm2125
| Summary | Full Text (HTML / PDF) |
February
letter
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
Ulrich K. Binné, Marie K. Classon, Frederick A. Dick, Wenyi Wei, Michael Rape, William G. Kaelin Jr., Anders M. Näär & Nicholas J. Dyson
Nature Cell Biology 9, 225–232
(February 2007); doi:10.1038/ncb1532
| First Paragraph | Full Text (HTML / PDF) |
news and views
The pRb-Cdh1-p27 autoamplifying network
Patricia G. Santamaría & Michele Pagano
Nature Cell Biology 9, 137–138
(February 2007); doi:10.1038/ncb0207-137
| Summary | Full Text (HTML / PDF) |
brief communication
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity
Eri Sakata, Yoshiki Yamaguchi, Yasuhiro Miyauchi, Kazuhiro Iwai, Tomoki Chiba, Yasushi Saeki, Noriyuki Matsuda, Keiji Tanaka & Koichi Kato
Nature Structural & Molecular Biology 14, 167–168
(February 2007); doi:10.1038/nsmb1191
| Summary | Full Text (HTML / PDF) |
January
article
Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity
Danny T. Huang, Harold W. Hunt, Min Zhuang, Melanie D. Ohi, James M. Holton and Brenda A. Schulman
Nature 445, 394–398
(25 January 2007); doi:10.1038/nature05490
| Summary | Full Text (HTML / PDF) |
review
Palmitoylation: policing protein stability and traffic
Maurine E. Linder and Robert J. Deschenes
Nature Reviews Molecular Cell Biology 8, 74–84
(January 2007); doi:10.1038/nrm2084
| Summary | Full Text (HTML / PDF) |
|
