letter Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination
Lucia Di Marcotullio, Elisabetta Ferretti, Azzura Greco, Enrico De Smaele, Agnese Po, Maria Anna Sico, Maurizio Alimandi, Giuseppe Giannini, Marella Maroder, Isabella Screpanti & Alberto Gulino Nature Cell Biology8, 1415–1423
(December 2006); doi:10.1038/ncb1510
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November
article Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes
Neeta S Roy, Carine Cleren, Shashi K Singh, Lichuan Yang, M Flint Beal & Steven A Goldman Nature Medicine12, 1259–1268
(November 2006); doi:10.1038/nm1495
| Summary | Full Text (HTML / PDF) |
A protein interaction network for pluripotency of embryonic stem cells
Jianlong Wang, Sridhar Rao, Jianlin Chu, Xiaohua Shen, Dana N. Levasseur, Thorold W. Theunissen and Stuart H. Orkin Nature444, 364–368
(16 November 2006); doi:10.1038/nature05284
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October
letter Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1
Jinqiu Zhang, Wai-Leong Tam, Guo Qing Tong, Qiang Wu, Hsiao-Yun Chan, Boon-Seng Soh, Yuefei Lou, Jianchang Yang, Yupo Ma, Li Chai, Huck-Hui Ng, Thomas Lufkin, Paul Robson & Bing Lim Nature Cell Biology8, 1114–1123
(2006); doi:10.1038/ncb1481
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article Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation
Marina Scheller, Joerg Huelsken, Frank Rosenbauer, Makoto M Taketo, Walter Birchmeier, Daniel G Tenen & Achim Leutz Nature Immunology7, 1037–1047
(October 2006); doi:10.1038/ni1387
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article Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block
Peggy Kirstetter, Kristina Anderson, Bo T Porse, Sten Eirik W Jacobsen & Claus Nerlov Nature Immunology7, 1048–1056
(October 2006); doi:10.1038/ni1381
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news and views Hematopoietic stem cell biology: too much of a Wnt thing
Jennifer J Trowbridge, Randall T Moon & Mickie Bhatia Nature Immunology7, 1021–1023
(October 2006); doi:10.1038/ni1006-1021
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September
article Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation
Johannes L Zakrzewski, Adam A Kochman, Sydney X Lu, Theis H Terwey, Theo D Kim, Vanessa M Hubbard, Stephanie J Muriglan, David Suh, Odette M Smith, Jeremy Grubin, Neel Patel, Andrew Chow, Javier Cabrera-Perez, Radhika Radhakrishnan, Adi Diab, Miguel-Angel Perales, Gabrielle Rizzuto, Ewa Menet, Eric G Pamer, Glen Heller, Juan Carlos Zúñiga-Pflücker, Õnder Alpdogan & Marcel R M van den Brink Nature Medicine12, 1039–1047
(2006); doi:10.1038/nm1463
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August
letter Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9
Andrei V. Krivtsov, David Twomey, Zhaohui Feng, Matthew C. Stubbs, Yingzi Wang, Joerg Faber, Jason E. Levine, Jing Wang, William C. Hahn, D. Gary Gilliland, Todd R. Golub and Scott A. Armstrong Nature442, 818–822
(10 August 2006); doi:10.1038/nature04976
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letter Notch signalling regulates stem cell numbers in vitro and in vivo
Andreas Androutsellis-Theotokis, Ronen R. Leker, Frank Soldner, Daniel J. Hoeppner, Rea Ravin, Steve W. Poser, Maria A. Rueger, Soo-Kyung Bae, Raja Kittappa and Ronald D. G. McKay Nature442, 823–826
(10 August 2006); doi:10.1038/nature04940
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article Dissecting self-renewal in stem cells with RNA interference
Natalia Ivanova, Radu Dobrin, Rong Lu, Iulia Kotenko, John Levorse, Christina DeCoste, Xenia Schafer, Yi Lun and Ihor R. Lemischka Nature442, 533–538
(02 August 2006); doi:10.1038/nature04915
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July
article Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
Vasily Shinin, Barbara Gayraud-Morel, Danielle Gomès & Shahragim Tajbakhsh Nature Cell Biology8, 677–682
(July 2006); doi:10.1038/ncb1425
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letter A germline-specific class of small RNAs binds mammalian Piwi proteins
Angélique Girard, Ravi Sachidanandam, Gregory J. Hannon and Michelle A. Carmell Nature442, 199–202
(13 July 2006); doi:10.1038/nature04917
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letter A novel class of small RNAs bind to MILI protein in mouse testes
Alexei Aravin , Dimos Gaidatzis, Sébastien Pfeffer, Mariana Lagos-Quintana, Pablo Landgraf, Nicola Iovino, Patricia Morris, Michael J. Brownstein, Satomi Kuramochi-Miyagawa, Toru Nakano, Minchen Chien, James J. Russo, Jingyue Ju, Robert Sheridan, Chris Sander, Mihaela Zavolan and Thomas Tuschl Nature442, 203–207
(13 July 2006); doi:10.1038/nature04916
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June
review article Brain tumour stem cells
Angelo L. Vescovi, Rossella Galli and Brent A. Reynolds Nature Reviews Cancer6, 425–436
(June 2006); doi:10.1038/nrc1889
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article Ovulated oocytes in adult mice derive from non-circulating germ cells
Kevin Eggan, Sara Jurga, Roger Gosden, Irene M. Min and Amy J. Wagers Nature441, 1109–1114
(29 June 2006); doi:10.1038/nature04929
| Summary | Full Text (HTML / PDF) |
letter Nanog promotes transfer of pluripotency after cell fusion
José Silva, Ian Chambers, Steven Pollard and Austin Smith Nature441, 997–1001
(22 June 2006); doi:10.1038/nature04914
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May
article Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Ömer H. Yilmaz, Riccardo Valdez, Brian K. Theisen, Wei Guo, David O. Ferguson, Hong Wu and Sean J. Morrison Nature441, 475–482
(May 2006); doi:10.1038/nature04703
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letter PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Jiwang Zhang, Justin C. Grindley, Tong Yin, Sachintha Jayasinghe, Xi C. He, Jason T. Ross, Jeffrey S. Haug, Dawn Rupp, Kimberly S. Porter-Westpfahl, Leanne M. Wiedemann, Hong Wu and Linheng Li Nature441, 518–522
(May 2006); doi:10.1038/nature04747
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news and views Stem cells: Good, bad and reformable
Viktor Janzen & David T. Scadden Nature441,418–419
(May 2006); doi:10.1038/441418b
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letter Polycomb complexes repress developmental regulators in murine embryonic stem cells
Laurie A. Boyer, Kathrin Plath , Julia Zeitlinger, Tobias Brambrink, Lea A. Medeiros, Tong Ihn Lee, Stuart S. Levine, Marius Wernig, Adriana Tajonar, Mridula K. Ray, George W. Bell, Arie P. Otte, Miguel Vidal, David K. Gifford, Richard A. Young and Rudolf Jaenisch Nature441, 349–353
(18 May 2006); doi:10.1038/nature04733
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article A unique function for cyclin D3 in early B cell development
A Byron Cooper, Catherine M Sawai, Ewa Sicinska, Sarah E Powers, Piotr Sicinski, Marcus R Clark, Iannis Aifantis Nature Immunology7, 489–497
(May 2006); doi:10.1038/ni1324
| Summary | Full Text (HTML / PDF) |
review article Organizing cell renewal in the intestine: stem cells, signals and combinatorial control
Cécile Crosnier, Despina Stamataki and Julian Lewis Nature Reviews Genetics7, 349–359
(May 2006); doi:10.1038/nrg1840
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April
review article From teratocarcinomas to embryonic stem cells and beyond: a history of embryonic stem cell research
Davor Solter Nature Reviews Genetics7, 319–327
(April 2006); doi:10.1038/nrg1827
| Summary | Full Text (HTML / PDF) |
letter Pluripotency of spermatogonial stem cells from adult mouse testis
Kaomei Guan, Karim Nayernia, Lars S. Maier, Stefan Wagner, Ralf Dressel, Jae Ho Lee, Jessica Nolte, Frieder Wolf, Manyu Li, Wolfgang Engel and Gerd Hasenfuss Nature440, 1199–1203
(27 April 2006); doi:10.1038/nature04697
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letter DNA methyltransferases control telomere length and telomere recombination in mammalian cells
Susana Gonzalo, Isabel Jaco, Mario F. Fraga, Taiping Chen, En Li, Manel Esteller & María A. Blasco Nature Cell Biology8, 416–424
(April 2006); doi:10.1038/ncb1386
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article Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
Keisuke Ito, Atsushi Hirao, Fumio Arai, Keiyo Takubo, Sahoko Matsuoka, Kana Miyamoto, Masako Ohmura, Kazuhito Naka, Kentaro Hosokawa, Yasuo Ikeda & Toshio Suda Nature Medicine12, 446–451
(April 2006); doi:10.1038/nm1388
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article The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
Yuin-Han Loh, Qiang Wu, Joon-Lin Chew, Vinsensius B Vega, Weiwei Zhang, Xi Chen, Guillaume Bourque, Joshy George, Bernard Leong, Jun Liu, Kee-Yew Wong, Ken W Sung, Charlie W H Lee, Xiao-Dong Zhao, Kuo-Ping Chiu, Leonard Lipovich, Vladimir A Kuznetsov, Paul Robson, Lawrence W Stanton, Chia-Lin Wei, Yijun Ruan, Bing Lim & Huck-Hui Ng Nature Genetics38, 431–440
(April 2006); doi:10.1038/ng1760
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March
research article Neurotrophins mediate human embryonic stem cell survival
April D Pyle, Leslie F Lock and Peter J Donovan Nature Biotechnology24, 344–350
(March 2006); doi:10.1038/nbt1189
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research article CD30 is a survival factor and a biomarker for transformed human pluripotent stem cells
Daniella Herszfeld, Ernst Wolvetang, Emma Langton-Bunker, Tung-Liang Chung, Adam A Filipczyk, Souheir Houssami, Pegah Jamshidi, Karen Koh, Andrew L Laslett, Anna Michalska, Linh Nguyen, Benjamin E Reubinoff, Irene Tellis, Jonathan M Auerbach, Carol J Ording, Leendert H J Looijenga and Martin F Pera Nature Biotechnology24, 351–357
(March 2006); doi:10.1038/nbt1197
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news and views The selfish stem cell
Peter W Andrews Nature Biotechnology24, 325–326
(March 2006); doi:10.1038/nbt0306-325
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article Pigment epithelium-derived factor is a niche signal for neural stem cell renewal
Carmen Ramírez-Castillejo, Francisco Sánchez-Sánchez, Celia Andreu-Agulló, Sacri R Ferrón, J Daniel Aroca-Aguilar, Pilar Sánchez, Helena Mira, Julio Escribano and Isabel Fariñas Nature Neuroscience9, 331–339
(March 2006); doi:10.1038/nn1657
| Abstract | Full Text (HTML/PDF) |
news and views PEDF: bridging neurovascular interactions in the stem cell niche
Kevin Pumiglia and Sally Temple Nature Neuroscience9, 299–300
(March 2006); doi:10.1038/nn0306-299
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February
letter Purification and unique properties of mammary epithelial stem cells
John Stingl, Peter Eirew, Ian Ricketson, Mark Shackleton, François Vaillant, David Choi, Haiyan I. Li and Connie J. Eaves Nature439, 993–997
(23 February 2006); doi:10.1038/nature04496
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brief communication Derivation of human embryonic stem cells in defined conditions
Tenneille E Ludwig, Mark E Levenstein, Jeffrey M Jones, W Travis Berggren, Erika R Mitchen, Jennifer L Frane, Leann J Crandall, Christine A Daigh, Kevin R Conard, Marian S Piekarczyk, Rachel A Llanas and James A Thomson Nature Biotechnology24, 185–187
(February 2006); doi:10.1038/nbt1177
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letter Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation
Cheng-Yu Lee, Kristin J. Robinson and Chris Q. Doe Nature439, 594–598
(02 February 2006); doi:10.1038/nature04299
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letter Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor
Gregor B. Adams, Karissa T. Chabner, Ian R. Alley, Douglas P. Olson, Zbigniew M. Szczepiorkowski , Mark C. Poznansky, Claudine H. Kos, Martin R. Pollak, Edward M. Brown and David T. Scadden Nature439, 599–603
(02 February 2006); doi:10.1038/nature04247
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January
letter The adult Drosophila posterior midgut is maintained by pluripotent stem cells
Benjamin Ohlstein and Allan Spradling Nature439, 470–474
(26 January 2006); doi:10.1038/nature04333
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letter Evidence that stem cells reside in the adult Drosophila midgut epithelium
Craig A. Micchelli and Norbert Perrimon Nature439, 475–479
(26 January 2006); doi:10.1038/nature04371
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letter A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference
Selda Samakoglu, Leszek Lisowski, Tulin Budak-Alpdogan, Yelena Usachenko, Santina Acuto, Rosalba Di Marzo, Aurelio Maggio, Ping Zhu, John F. Tisdale, Isabelle Rivière and Michel Sadelain Nature Biotechnology24, 89–94
(January 2006); doi:10.1038/nbt1176
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letter Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts
Alexander Meissner and Rudolf Jaenisch Nature439, 212–215
(12 January 2006); doi:10.1038/nature04257
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letter Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres
Young Chung, Irina Klimanskaya, Sandy Becker, Joel Marh, Shi-Jiang Lu, Julie Johnson, Lorraine Meisner and Robert Lanza Nature439, 216–219
(12 January 2006); doi:10.1038/nature04277
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news and views Medicine: Politic stem cells
Irving L. Weissman Nature439, 145–147
(12 January 2006); doi:10.1038/439145a
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letter Generation of a functional mammary gland from a single stem cell
Mark Shackleton, François Vaillant, Kaylene J. Simpson, John Stingl, Gordon K. Smyth, Marie-Liesse Asselin-Labat, Li Wu, Geoffrey J. Lindeman and Jane E. Visvader Nature439, 84–88
(05 January 2006); doi:10.1038/nature04372
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article Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation
Jennifer J Trowbridge, Anargyros Xenocostas, Randall T Moon and Mickie Bhatia Nature Medicine12, 89–98
(January 2006); doi:10.1038/nm1339
| Abstract | Full Text (HTML/PDF) |
