letter Nanog safeguards pluripotency and mediates germline development
Ian Chambers et al. Nature450, 12301234
(20 December 2007); doi:10.1038/nature06403
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November
review MLL translocations, histone modifications and leukaemia stem-cell development
Andrei V. Krivtsov & Scott A. Armstrong Nature Reviews Cancer7, 823833
(November 2007); doi:10.1038/nrc2253
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article Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium
Xavier Morin, Florence Jaouen & Pascale Durbec Nature Neuroscience10, 14401448
(November 2007); doi:10.1038/nn1984
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letter Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
Fumihiko Ishikawa et al. Nature Biotechnology25, 13151321
(November 2007); doi:10.1038/nbt1350
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October
article Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al. Nature449, 10031007
(25 October 2007); doi:10.1038/nature06196
| Summary | Full Text (HTML / PDF) |
review Telomere length, stem cells and aging
Maria A Blasco Nature Chemical Biology3, 640649
(October 2007); doi:10.1038/nchembio.2007.38
| Summary | Full Text (HTML / PDF) |
letter Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
Alexander Meissner, Marius Wernig & Rudolf Jaenisch Nature Biotechnology25, 11771181
(October 2007); doi:10.1038/nbt1335
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September
review How stem cells age and why this makes us grow old
Norman E. Sharpless & Ronald A. DePinho Nature Reviews Molecular Cell Biology8, 703713
(September 2007); doi:10.1038/nrm2241
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letter Generation of functional multipotent adult stem cells from GPR125+ germline progenitors
Marco Seandel, Daylon James, Sergey V. Shmelkov, Ilaria Falciatori, Jiyeon Kim, Sai Chavala, Douglas S. Scherr, Fan Zhang, Richard Torres, Nicholas W. Gale, George D. Yancopoulos, Andrew Murphy, David M. Valenzuela, Robin M. Hobbs, Pier Paolo Pandolfi & Shahin Rafii Nature449, 346350
(20 September 2007); doi:10.1038/nature06129
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letter Differential Notch signalling distinguishes neural stem cells from intermediate progenitors
Ken-ichi Mizutani, Keejung Yoon, Louis Dang, Akinori Tokunaga & Nicholas Gaiano Nature449, 351355
(20 September 2007); doi:10.1038/nature06090
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letter Toll-like receptors modulate adult hippocampal neurogenesis
Asya Rolls, Ravid Shechter, Anat London, Yaniv Ziv, Ayal Ronen, Rinat Levy & Michal Schwartz Nature Cell Biology9, 10811088
(September 2007); doi:10.1038/ncb1629
| Summary | Full Text (HTML / PDF) |
news and views Neural stem cells: guardians of the brain
Gianvito Martino & Stefano Pluchino Nature Cell Biology9, 10311034
(September 2007); doi:10.1038/ncb0907-1031
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letter Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
Hongyan Wang, Yingshi Ouyang, W. Gregory Somers, William Chia & Bingwei Lu Nature449, 96100
(6 September 2007); doi:10.1038/nature06056
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perspective Patching the gaps in Hedgehog signalling
Rajat Rohatgi & Matthew P. Scott Nature Cell Biology9, 10051009
(September 2007); doi:10.1038/ncb435
| Summary | Full Text (HTML / PDF) |
August
article IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
Sean C. Bendall, Morag H. Stewart, Pablo Menendez, Dustin George, Kausalia Vijayaragavan, Tamra Werbowetski-Ogilvie, Veronica Ramos-Mejia, Anne Rouleau, Jiabi Yang, Marc Bossé, Gilles Lajoie & Mickie Bhatia Nature448, 10151021
(30 August 2007); doi:10.1038/nature06027
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news and views Reprogramming by the numbers
Shin-ichi Nishikawa Nature Biotechnology25, 877878
(August 2007); doi:10.1038/nbt0807-877
| Summary | Full Text (HTML / PDF) |
perspective Embryonic stem cells as a source of models for drug discovery
Colin W. Pouton & John M. Haynes Nature Reviews Drug Discovery6, 605616
(August 2007); doi:10.1038/nrd2194
| Summary | Full Text (HTML / PDF) |
news and views Debugging cellular reprogramming
In-Hyun Park & George Q. Daley Nature Cell Biology9, 871873
(August 2007); doi:10.1038/ncb0807-871
| Summary | Full Text (HTML / PDF) |
article Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe, Biju Issac, Erez Lieberman, Georgia Giannoukos, Pablo Alvarez, William Brockman, Tae-Kyung Kim, Richard P. Koche, William Lee, Eric Mendenhall, Aisling O'Donovan, Aviva Presser, Carsten Russ, Xiaohui Xie, Alexander Meissner, Marius Wernig, Rudolf Jaenisch, Chad Nusbaum, Eric S. Lander & Bradley E. Bernstein Nature448, 553560
(2 August 2007); doi:10.1038/nature06008
| Summary | Full Text (HTML / PDF) |
July
article Generation of germline-competent induced pluripotent stem cells
Keisuke Okita, Tomoko Ichisaka & Shinya Yamanaka Nature448, 313317
(19 July 2007); doi:10.1038/nature05934
| Summary | Full Text (HTML / PDF) |
article In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
Marius Wernig, Alexander Meissner, Ruth Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, Bradley E. Bernstein & Rudolf Jaenisch Nature448, 318324
(19 July 2007); doi:10.1038/nature05944
| Summary | Full Text (HTML / PDF) |
resources Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
The International Stem Cell Initiative Nature Biotechnology25, 803816
(July 2007); doi:10.1038/nbt1318
| Summary | Full Text (HTML / PDF) |
letter Derivation of pluripotent epiblast stem cells from mammalian embryos
I. Gabrielle M. Brons, Lucy E. Smithers, Matthew W. B. Trotter, Peter Rugg-Gunn, Bowen Sun, Susana M. Chuva de Sousa Lopes, Sarah K. Howlett, Amanda Clarkson, Lars Ahrlund-Richter, Roger A. Pedersen & Ludovic Vallier Nature448, 191195
(12 July 2007); doi:10.1038/nature05950
| Summary | Full Text (HTML / PDF) |
letter New cell lines from mouse epiblast share defining features with human embryonic stem cells
Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook, Timothy J. Davies, Edward P. Evans, David L. Mack, Richard L. Gardner & Ronald D. G. McKay Nature448, 196199
(12 July 2007); doi:10.1038/nature05972
| Summary | Full Text (HTML / PDF) |
June
article Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells
Nicolas Plachta, Christine Annaheim, Stephanie Bissière, Shuo Lin, Markus Rüegg, Sjouke Hoving, Dieter Müller, Françoise Poirier, Miriam Bibel & Yves-Alain Barde Nature Neuroscience10, 712719
(June 2007); doi:10.1038/nn1897
| Summary | Full Text (HTML / PDF) |
letter Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
Trista E. North, Wolfram Goessling, Carl R. Walkley, Claudia Lengerke, Kamden R. Kopani, Allegra M. Lord, Gerhard J. Weber, Teresa V. Bowman, Il-Ho Jang, Tilo Grosser, Garret A. FitzGerald, George Q. Daley, Stuart H. Orkin & Leonard I. Zon Nature447, 10071011
(21 June 2007); doi:10.1038/nature05883
| Summary | Full Text (HTML / PDF) |
review Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells
Cayetano Gonzalez Nature Reviews Genetics8, 462472
(June 2007); doi:10.1038/nrg2103
| Summary | Full Text (HTML / PDF) |
article Generation of functional hemangioblasts from human embryonic stem cells
Shi-Jiang Lu, Qiang Feng, Sergio Caballero, Yu Chen, Malcolm A S Moore, Maria B Grant & Robert Lanzaamp; Nature Methods4, 501509
(June 2007); doi:10.1038/nmeth1041
| Summary | Full Text (HTML / PDF) |
letter A ROCK inhibitor permits survival of dissociated human embryonic stem cells
Kiichi Watanabe, Morio Ueno, Daisuke Kamiya, Ayaka Nishiyama, Michiru Matsumura, Takafumi Wataya, Jun B Takahashi, Satomi Nishikawa, Shin-ichi Nishikawa, Keiko Muguruma & Yoshiki Sasai Nature Biotechnology25, 681686
(June 2007); doi:10.1038/nbt1310
| Summary | Full Text (HTML / PDF) |
article DNA repair is limiting for haematopoietic stem cells during ageing
Anastasia Nijnik, Lisa Woodbine, Caterina Marchetti, Sara Dawson, Teresa Lambe, Cong Liu, Neil P. Rodrigues, Tanya L. Crockford, Erik Cabuy, Alessandro Vindigni, Tariq Enver, John I. Bell, Predrag Slijepcevic, Christopher C. Goodnow, Penelope A. Jeggo & Richard J. Cornall Nature447, 686690
(7 June 2007); doi:10.1038/nature05875
| Summary | Full Text (HTML / PDF) |
letter Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
Derrick J. Rossi, David Bryder, Jun Seita, Andre Nussenzweig, Jan Hoeijmakers & Irving L. Weissman Nature447, 725729
(7 June 2007); doi:10.1038/nature05862
| Summary | Full Text (HTML / PDF) |
article Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Shinji Masui, Yuhki Nakatake, Yayoi Toyooka, Daisuke Shimosato, Rika Yagi, Kazue Takahashi, Hitoshi Okochi, Akihiko Okuda, Ryo Matoba, Alexei A. Sharov, Minoru S. H. Ko & Hitoshi Niwa Nature Cell Biology9, 625635
(June 2007); doi:10.1038/ncb1589
| Summary | Full Text (HTML / PDF) |
perspective Embryonic stem-cell culture as a tool for developmental cell biology
Shin-Ichi Nishikawa, Lars Martin Jakt & Takumi Era Nature Reviews Molecular Cell Biology8, 502507
(June 2007); doi:10.1038/nrm2189
| Summary | Full Text (HTML / PDF) |
May
review Stem-cell niches: nursery rhymes across kingdoms
Ben Scheres Nature Reviews Molecular Cell Biology8, 345354
(May 2007); doi:10.1038/nrm2164
| Summary | Full Text (HTML / PDF) |
letter Chemical genetics reveals a complex functional ground state of neural stem cells
Phedias Diamandis, Jan Wildenhain, Ian D Clarke, Adrian G Sacher, Jeremy Graham, David S Bellows, Erick K M Ling, Ryan J Ward, Leanne G Jamieson, Mike Tyers and Peter B Dirks Nature Chemical Biology3, 268273
(May 2007); doi:10.1038/nchembio873
| Summary | Full Text (HTML / PDF) |
news and views Chemical probes of neural stem cell self-renewal
Mark Mercola Nature Chemical Biology3, 246247
(May 2007); doi:10.1038/nchembio0507-246
| Summary | Full Text (HTML / PDF) |
April
review Epigenetic signatures of stem-cell identity
Mikhail Spivakov and Amanda G. Fisher Nature Reviews Genetics8, 263271
(April 2007); doi:10.1038/nrg2046
| Summary | Full Text (HTML / PDF) |
review Reprogramming metastatic tumour cells with embryonic microenvironments
Mary J. C. Hendrix, Elisabeth A. Seftor, Richard E. B. Seftor, Jennifer Kasemeier-Kulesa, Paul M. Kulesa & Lynne-Marie Postovit Nature Reviews Cancer7, 246255
(April 2007); doi:10.1038/nrc2108
| Summary | Full Text (HTML / PDF) |
March
letter A single type of progenitor cell maintains normal epidermis
Elizabeth Clayton, David P. Doupé, Allon M. Klein, Douglas J. Winton, Benjamin D. Simons and Philip H. Jones Nature446, 185189
(8 March 2007); doi:10.1038/nature05574
| Summary | Full Text (HTML / PDF) |
February
brief communication Epigenetic stem cell signature in cancer
Martin Widschwendter, Heidi Fiegl, Daniel Egle, Elisabeth Mueller-Holzner, Gilbert Spizzo, Christian Marth, Daniel J Weisenberger, Mihaela Campan, Joanne Young, Ian Jacobs & Peter W Laird Nature Genetics39, 157158
(February 2007); doi:10.1038/ng1941
| Summary | Full Text (HTML / PDF) |
review Myelodysplastic syndromes: the complexity of stem-cell diseases
Seth J. Corey, Mark D. Minden, Dwayne L. Barber, Hagop Kantarjian, Jean C. Y. Wang and Aaron D. Schimmer Nature Reviews Cancer7, 118129
(February 2007); doi:10.1038/nrc2047
| Summary | Full Text (HTML / PDF) |
January
article Isolation of amniotic stem cell lines with potential for therapy
Paolo De Coppi, Georg Bartsch Jr, M Minhaj Siddiqui, Tao Xu, Cesar C Santos, Laura Perin, Gustavo Mostoslavsky, Angéline C Serre, Evan Y Snyder, James J Yoo, Mark E Furth, Shay Soker & Anthony Atala Nature Biotechnology25, 100106
(January 2007); doi:10.1038/nbt1274
| Summary | Full Text (HTML / PDF) |
letter A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien, Aaron Pollett, Steven Gallinger and John E. Dick Nature445, 106110
(4 January 2007); doi:10.1038/nature05372
| First Paragraph | Full Text (HTML / PDF) |
letter Identification and expansion of human colon-cancer-initiating cells
Lucia Ricci-Vitiani, Dario G. Lombardi, Emanuela Pilozzi, Mauro Biffoni, Matilde Todaro, Cesare Peschle and Ruggero De Maria Nature445, 111115
(4 January 2007); doi:10.1038/nature05384
| First Paragraph | Full Text (HTML / PDF) |
letter Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
Aaheli Roy Choudhury, Zhenyu Ju, Meta W Djojosubroto, Andrea Schienke, Andre Lechel, Sonja Schaetzlein, Hong Jiang, Anna Stepczynska, Chunfang Wang, Jan Buer, Han-Woong Lee, Thomas von Zglinicki, Arnold Ganser, Peter Schirmacher, Hiromitsu Nakauchi & K Lenhard Rudolph Nature Genetics39, 99105
(January 2007); doi:10.1038/ng1937
| Fisrt Paragraph | Full Text (HTML / PDF) |
news and views Telomeres, p21 and the cancer-aging hypothesis
Jessica F Bell & Norman E Sharpless Nature Genetics39, 1112
(January 2007); doi:10.1038/ng0107-11
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