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Research library: Stem cells

2007: December | November | October | September | August | July | June | May | April | March | February | January

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letter
Nanog safeguards pluripotency and mediates germline development
Ian Chambers et al.
Nature 450, 1230–1234
(20 December 2007); doi:10.1038/nature06403
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review
MLL translocations, histone modifications and leukaemia stem-cell development
Andrei V. Krivtsov & Scott A. Armstrong
Nature Reviews Cancer 7, 823–833
(November 2007); doi:10.1038/nrc2253
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article
Control of planar divisions by the G-protein regulator LGN maintains progenitors in the chick neuroepithelium
Xavier Morin, Florence Jaouen & Pascale Durbec
Nature Neuroscience 10, 1440–1448
(November 2007); doi:10.1038/nn1984
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letter
Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region
Fumihiko Ishikawa et al.
Nature Biotechnology 25, 1315–1321
(November 2007); doi:10.1038/nbt1350
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article
Identification of stem cells in small intestine and colon by marker gene Lgr5
Nick Barker et al.
Nature 449, 1003–1007
(25 October 2007); doi:10.1038/nature06196
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review
Telomere length, stem cells and aging
Maria A Blasco
Nature Chemical Biology 3, 640–649
(October 2007); doi:10.1038/nchembio.2007.38
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letter
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells
Alexander Meissner, Marius Wernig & Rudolf Jaenisch
Nature Biotechnology 25, 1177–1181
(October 2007); doi:10.1038/nbt1335
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review
How stem cells age and why this makes us grow old
Norman E. Sharpless & Ronald A. DePinho
Nature Reviews Molecular Cell Biology 8, 703–713
(September 2007); doi:10.1038/nrm2241
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letter
Generation of functional multipotent adult stem cells from GPR125+ germline progenitors
Marco Seandel, Daylon James, Sergey V. Shmelkov, Ilaria Falciatori, Jiyeon Kim, Sai Chavala, Douglas S. Scherr, Fan Zhang, Richard Torres, Nicholas W. Gale, George D. Yancopoulos, Andrew Murphy, David M. Valenzuela, Robin M. Hobbs, Pier Paolo Pandolfi & Shahin Rafii
Nature 449, 346–350
(20 September 2007); doi:10.1038/nature06129
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letter
Differential Notch signalling distinguishes neural stem cells from intermediate progenitors
Ken-ichi Mizutani, Keejung Yoon, Louis Dang, Akinori Tokunaga & Nicholas Gaiano
Nature 449, 351–355
(20 September 2007); doi:10.1038/nature06090
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letter
Toll-like receptors modulate adult hippocampal neurogenesis
Asya Rolls, Ravid Shechter, Anat London, Yaniv Ziv, Ayal Ronen, Rinat Levy & Michal Schwartz
Nature Cell Biology 9, 1081–1088
(September 2007); doi:10.1038/ncb1629
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news and views
Neural stem cells: guardians of the brain
Gianvito Martino & Stefano Pluchino
Nature Cell Biology 9, 1031–1034
(September 2007); doi:10.1038/ncb0907-1031
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letter
Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon
Hongyan Wang, Yingshi Ouyang, W. Gregory Somers, William Chia & Bingwei Lu
Nature 449, 96–100
(6 September 2007); doi:10.1038/nature06056
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perspective
Patching the gaps in Hedgehog signalling
Rajat Rohatgi & Matthew P. Scott
Nature Cell Biology 9, 1005–1009
(September 2007); doi:10.1038/ncb435
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article
IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro
Sean C. Bendall, Morag H. Stewart, Pablo Menendez, Dustin George, Kausalia Vijayaragavan, Tamra Werbowetski-Ogilvie, Veronica Ramos-Mejia, Anne Rouleau, Jiabi Yang, Marc Bossé, Gilles Lajoie & Mickie Bhatia
Nature 448, 1015–1021
(30 August 2007); doi:10.1038/nature06027
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news and views
Reprogramming by the numbers
Shin-ichi Nishikawa
Nature Biotechnology 25, 877–878
(August 2007); doi:10.1038/nbt0807-877
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perspective
Embryonic stem cells as a source of models for drug discovery
Colin W. Pouton & John M. Haynes
Nature Reviews Drug Discovery 6, 605–616
(August 2007); doi:10.1038/nrd2194
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news and views
Debugging cellular reprogramming
In-Hyun Park & George Q. Daley
Nature Cell Biology 9, 871–873
(August 2007); doi:10.1038/ncb0807-871
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article
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe, Biju Issac, Erez Lieberman, Georgia Giannoukos, Pablo Alvarez, William Brockman, Tae-Kyung Kim, Richard P. Koche, William Lee, Eric Mendenhall, Aisling O'Donovan, Aviva Presser, Carsten Russ, Xiaohui Xie, Alexander Meissner, Marius Wernig, Rudolf Jaenisch, Chad Nusbaum, Eric S. Lander & Bradley E. Bernstein
Nature 448, 553–560
(2 August 2007); doi:10.1038/nature06008
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article
Generation of germline-competent induced pluripotent stem cells
Keisuke Okita, Tomoko Ichisaka & Shinya Yamanaka
Nature 448, 313–317
(19 July 2007); doi:10.1038/nature05934
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article
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
Marius Wernig, Alexander Meissner, Ruth Foreman, Tobias Brambrink, Manching Ku, Konrad Hochedlinger, Bradley E. Bernstein & Rudolf Jaenisch
Nature 448, 318–324
(19 July 2007); doi:10.1038/nature05944
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resources
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative
The International Stem Cell Initiative
Nature Biotechnology 25, 803–816
(July 2007); doi:10.1038/nbt1318
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letter
Derivation of pluripotent epiblast stem cells from mammalian embryos
I. Gabrielle M. Brons, Lucy E. Smithers, Matthew W. B. Trotter, Peter Rugg-Gunn, Bowen Sun, Susana M. Chuva de Sousa Lopes, Sarah K. Howlett, Amanda Clarkson, Lars Ahrlund-Richter, Roger A. Pedersen & Ludovic Vallier
Nature 448, 191–195
(12 July 2007); doi:10.1038/nature05950
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letter
New cell lines from mouse epiblast share defining features with human embryonic stem cells
Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook, Timothy J. Davies, Edward P. Evans, David L. Mack, Richard L. Gardner & Ronald D. G. McKay
Nature 448, 196–199
(12 July 2007); doi:10.1038/nature05972
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article
Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells
Nicolas Plachta, Christine Annaheim, Stephanie Bissière, Shuo Lin, Markus Rüegg, Sjouke Hoving, Dieter Müller, Françoise Poirier, Miriam Bibel & Yves-Alain Barde
Nature Neuroscience 10, 712–719
(June 2007); doi:10.1038/nn1897
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letter
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
Trista E. North, Wolfram Goessling, Carl R. Walkley, Claudia Lengerke, Kamden R. Kopani, Allegra M. Lord, Gerhard J. Weber, Teresa V. Bowman, Il-Ho Jang, Tilo Grosser, Garret A. FitzGerald, George Q. Daley, Stuart H. Orkin & Leonard I. Zon
Nature 447, 1007–1011
(21 June 2007); doi:10.1038/nature05883
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review
Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells
Cayetano Gonzalez
Nature Reviews Genetics 8, 462–472
(June 2007); doi:10.1038/nrg2103
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article
Generation of functional hemangioblasts from human embryonic stem cells
Shi-Jiang Lu, Qiang Feng, Sergio Caballero, Yu Chen, Malcolm A S Moore, Maria B Grant & Robert Lanzaamp;
Nature Methods 4, 501–509
(June 2007); doi:10.1038/nmeth1041
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letter
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
Kiichi Watanabe, Morio Ueno, Daisuke Kamiya, Ayaka Nishiyama, Michiru Matsumura, Takafumi Wataya, Jun B Takahashi, Satomi Nishikawa, Shin-ichi Nishikawa, Keiko Muguruma & Yoshiki Sasai
Nature Biotechnology 25, 681–686
(June 2007); doi:10.1038/nbt1310
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article
DNA repair is limiting for haematopoietic stem cells during ageing
Anastasia Nijnik, Lisa Woodbine, Caterina Marchetti, Sara Dawson, Teresa Lambe, Cong Liu, Neil P. Rodrigues, Tanya L. Crockford, Erik Cabuy, Alessandro Vindigni, Tariq Enver, John I. Bell, Predrag Slijepcevic, Christopher C. Goodnow, Penelope A. Jeggo & Richard J. Cornall
Nature 447, 686–690
(7 June 2007); doi:10.1038/nature05875
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letter
Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age
Derrick J. Rossi, David Bryder, Jun Seita, Andre Nussenzweig, Jan Hoeijmakers & Irving L. Weissman
Nature 447, 725–729
(7 June 2007); doi:10.1038/nature05862
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article
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Shinji Masui, Yuhki Nakatake, Yayoi Toyooka, Daisuke Shimosato, Rika Yagi, Kazue Takahashi, Hitoshi Okochi, Akihiko Okuda, Ryo Matoba, Alexei A. Sharov, Minoru S. H. Ko & Hitoshi Niwa
Nature Cell Biology 9, 625–635
(June 2007); doi:10.1038/ncb1589
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perspective
Embryonic stem-cell culture as a tool for developmental cell biology
Shin-Ichi Nishikawa, Lars Martin Jakt & Takumi Era
Nature Reviews Molecular Cell Biology 8, 502–507
(June 2007); doi:10.1038/nrm2189
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review
Stem-cell niches: nursery rhymes across kingdoms
Ben Scheres
Nature Reviews Molecular Cell Biology 8, 345–354
(May 2007); doi:10.1038/nrm2164
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letter
Chemical genetics reveals a complex functional ground state of neural stem cells
Phedias Diamandis, Jan Wildenhain, Ian D Clarke, Adrian G Sacher, Jeremy Graham, David S Bellows, Erick K M Ling, Ryan J Ward, Leanne G Jamieson, Mike Tyers and Peter B Dirks
Nature Chemical Biology 3, 268–273
(May 2007); doi:10.1038/nchembio873
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news and views
Chemical probes of neural stem cell self-renewal
Mark Mercola
Nature Chemical Biology 3, 246–247
(May 2007); doi:10.1038/nchembio0507-246
| Summary | Full Text (HTML / PDF) |

review
Epigenetic signatures of stem-cell identity
Mikhail Spivakov and Amanda G. Fisher
Nature Reviews Genetics 8, 263–271
(April 2007); doi:10.1038/nrg2046
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review
Reprogramming metastatic tumour cells with embryonic microenvironments
Mary J. C. Hendrix, Elisabeth A. Seftor, Richard E. B. Seftor, Jennifer Kasemeier-Kulesa, Paul M. Kulesa & Lynne-Marie Postovit
Nature Reviews Cancer 7, 246–255
(April 2007); doi:10.1038/nrc2108
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letter
A single type of progenitor cell maintains normal epidermis
Elizabeth Clayton, David P. Doupé, Allon M. Klein, Douglas J. Winton, Benjamin D. Simons and Philip H. Jones
Nature 446, 185–189
(8 March 2007); doi:10.1038/nature05574
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brief communication
Epigenetic stem cell signature in cancer
Martin Widschwendter, Heidi Fiegl, Daniel Egle, Elisabeth Mueller-Holzner, Gilbert Spizzo, Christian Marth, Daniel J Weisenberger, Mihaela Campan, Joanne Young, Ian Jacobs & Peter W Laird
Nature Genetics 39, 157–158
(February 2007); doi:10.1038/ng1941
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review
Myelodysplastic syndromes: the complexity of stem-cell diseases
Seth J. Corey, Mark D. Minden, Dwayne L. Barber, Hagop Kantarjian, Jean C. Y. Wang and Aaron D. Schimmer
Nature Reviews Cancer 7, 118–129
(February 2007); doi:10.1038/nrc2047
| Summary | Full Text (HTML / PDF) |

article
Isolation of amniotic stem cell lines with potential for therapy
Paolo De Coppi, Georg Bartsch Jr, M Minhaj Siddiqui, Tao Xu, Cesar C Santos, Laura Perin, Gustavo Mostoslavsky, Angéline C Serre, Evan Y Snyder, James J Yoo, Mark E Furth, Shay Soker & Anthony Atala
Nature Biotechnology 25, 100–106
(January 2007); doi:10.1038/nbt1274
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letter
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine A. O'Brien, Aaron Pollett, Steven Gallinger and John E. Dick
Nature 445, 106–110
(4 January 2007); doi:10.1038/nature05372
| First Paragraph | Full Text (HTML / PDF) |

letter
Identification and expansion of human colon-cancer-initiating cells
Lucia Ricci-Vitiani, Dario G. Lombardi, Emanuela Pilozzi, Mauro Biffoni, Matilde Todaro, Cesare Peschle and Ruggero De Maria
Nature 445, 111–115
(4 January 2007); doi:10.1038/nature05384
| First Paragraph | Full Text (HTML / PDF) |

letter
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
Aaheli Roy Choudhury, Zhenyu Ju, Meta W Djojosubroto, Andrea Schienke, Andre Lechel, Sonja Schaetzlein, Hong Jiang, Anna Stepczynska, Chunfang Wang, Jan Buer, Han-Woong Lee, Thomas von Zglinicki, Arnold Ganser, Peter Schirmacher, Hiromitsu Nakauchi & K Lenhard Rudolph
Nature Genetics 39, 99–105
(January 2007); doi:10.1038/ng1937
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news and views
Telomeres, p21 and the cancer-aging hypothesis
Jessica F Bell & Norman E Sharpless
Nature Genetics 39, 11–12
(January 2007); doi:10.1038/ng0107-11
| Summary | Full Text (HTML / PDF) |

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