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Research library: Stress signaling

2008: | December | November | October | September | August | July | June | May | April | March | February | January

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article
Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin
Yoshihiro Dohi et al.
Nature Structural & Molecular Biology 15, 1246–1254
(December 2008); doi:10.1038/nsmb.1516
| Summary | Full Text (HTML / PDF) |

article
Structure and function of a transcriptional network activated by the MAPK Hog1
Andrew P Capaldi et al.
Nature Genetics 40, 1300–1306
(November 2008); doi:10.1038/ng.235
| Summary | Full Text (HTML / PDF) |

perspective
Ageing, oxidative stress and cancer: paradigms in parallax
Christopher C. Benz & Christina Yau
Nature Reviews Cancer 8, 875–879
(November 2008); doi:10.1038/nrc2522
| Summary | Full Text (HTML / PDF) |

letter
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
Kyoko Arimoto, Hiroyuki Fukuda, Shinobu Imajoh-Ohmi, Haruo Saito & Mutsuhiro Takekawa
Nature Cell Biology 10, 1324–1332
(November 2008); doi:10.1038/ncb1791
| Summary | Full Text (HTML / PDF) |

review
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
William G. Kaelin Jr
Nature Reviews Cancer 8, 865–873
(November 2008); doi:10.1038/nrc2502
| Summary | Full Text (HTML / PDF) |

review
Hypoxia signalling through mTOR and the unfolded protein response in cancer
Bradly G. Wouters & Marianne Koritzinsky
Nature Reviews Cancer 8, 851–864
(November 2008); doi:10.1038/nrc2501
| Summary | Full Text (HTML / PDF) |

letter
A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly
Takbum Ohn, Nancy Kedersha, Tyler Hickman, Sarah Tisdale & Paul Anderson
Nature Cell Biology 10, 1224–1231
(October 2008); doi:10.1038/ncb1783
| Summary | Full Text (HTML / PDF) |

news and views
Stressed out? Make some modifications!
Angela Hilliker & Roy Parker
Nature Cell Biology 10, 1129–1130
(October 2008); doi:10.1038/ncb1008-1129
| Full Text (HTML / PDF) |

review
The role of the RB tumour suppressor pathway in oxidative stress responses in the haematopoietic system
Kay F. Macleod
Nature Reviews Cancer 8, 769–781
(October 2008); doi:10.1038/nrc2504
| Summary | Full Text (HTML / PDF) |

article
Mincle is an ITAM-coupled activating receptor that senses damaged cells
Sho Yamasaki, Eri Ishikawa, Machie Sakuma, Hiromitsu Hara, Koji Ogata & Takashi Saito
Nature Immunology 9, 1179–1188
(October 2008); doi:10.1038/ni.1651
| Summary | Full Text (HTML / PDF) |

news and views
Sensing necrosis with Mincle
Gordon D Brown
Nature Immunology 9, 1099–1100
(October 2008); doi:10.1038/ni1008-1099
| Full Text (HTML / PDF) |

review
A complex barcode underlies the heterogeneous response of p53 to stress
Fiona Murray-Zmijewski, Elizabeth A. Slee & Xin Lu
Nature Reviews Molecular Cell Biology 9, 702–712
(September 2008); doi:10.1038/nrm2451
| Summary | Full Text (HTML / PDF) |

article
Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
Noam Stern-Ginossar et al.
Nature Immunology 9, 1065–1073
(September 2008); doi:10.1038/ni.1642
| Summary | Full Text (HTML / PDF) |

news and views
Regulation of NKG2D ligands: a purposeful but delicate affair
Thomas Spies
Nature Immunology 9, 1013–1015
(September 2008); doi:10.1038/ni0908-1013
| Full Text (HTML / PDF) |

perspective
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Nicholas C. Denko
Nature Reviews Cancer 8, 705–713
(September 2008); doi:10.1038/nrc2468
| Summary | Full Text (HTML / PDF) |

review
The endoplasmic reticulum stress response in immunity and autoimmunity
Derrick J. Todd, Ann-Hwee Lee & Laurie H. Glimcher
Nature Reviews Immunology 8, 663–674
(September 2008); doi:10.1038/nri2359
| Summary | Full Text (HTML / PDF) |

review
Puzzles, promises and a cure for ageing
Jan Vijg & Judith Campisi
Nature 454, 1065–1071
(28 August 2008); doi:10.1038/nature07216
| Summary | Full Text (HTML / PDF) |

article
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
Felix Meissner, Kaaweh Molawi & Arturo Zychlinsky
Nature Immunology 9, 866–872
(August 2008); doi:10.1038/ni.1633
| Summary | Full Text (HTML / PDF) |

article
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress
Irina M Bochkis et al.
Nature Medicine 14, 828–836
(August 2008); doi:10.1038/nm.1853
| Summary | Full Text (HTML / PDF) |

article
UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals
Zane B. Andrews et al.
Nature 454, 846–851
(14 August 2008); doi:10.1038/nature07181
| Summary | Full Text (HTML / PDF) |

letter
A tumor necrosis factor-α–mediated pathway promoting autosomal dominant polycystic kidney disease
Xiaogang Li et al.
Nature Medicine 14, 863–868
doi:10.1038/nm1783
| Summary | Full Text (HTML / PDF) |

review
Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation
Luis López-Maury, Samuel Marguerat & Jürg Bähler
Nature Reviews Genetics 9, 583–593
(August 2008); doi:10.1038/nrg2398
| Summary | Full Text (HTML / PDF) |

brief communication
Molecular recognition of nitrated fatty acids by PPARγ
Yong Li et al.
Nature Structural & Molecular Biology 15, 865–867
(August 2008); doi:10.1038/nsmb.1447
| Summary | Full Text (HTML / PDF) |

article
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim, Pankuri Goraksha-Hicks, Li Li, Thomas P. Neufeld & Kun-Liang Guan
Nature Cell Biology 10, 935–945
(August 2008); doi:10.1038/ncb1753
| Summary | Full Text (HTML / PDF) |

news and views
Nutrient sensing: TOR's Ragtime
Alfred J. Meijer & Patrice Codogno
Nature Cell Biology 10, 881–883
(August 2008); doi:10.1038/ncb0808-881
| Full Text (HTML / PDF) |

article
Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
Roger Pocock & Oliver Hobert
Nature Neuroscience 11, 894–900
(August 2008); doi:10.1038/nn.2152
| Summary | Full Text (HTML / PDF) |

news and views
Fresh air is good for nerves: hypoxia disturbs axon guidance
Chun-Liang Pan & Gian Garriga
Nature Neuroscience 11, 859–861
(August 2008); doi:10.1038/nn0808-859
| Full Text (HTML / PDF) |

review
From endoplasmic-reticulum stress to the inflammatory response
Kezhong Zhang & Randal J. Kaufman
Nature 454, 455–462
(24 July 2008); doi:10.1038/nature07203
| Summary | Full Text (HTML / PDF) |

letter
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis
Nilkantha Sen et al.
Nature Cell Biology 10, 866–873
(July 2008); doi:10.1038/ncb1747
| Summary | Full Text (HTML / PDF) |

article
NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer
Rainer Fagerholm et al.
Nature Genetics 40, 844–853
doi:10.1038/ng.155
| Summary | Full Text (HTML / PDF) |

review
Cytochrome c: functions beyond respiration
Yong-Ling P. Ow, Douglas R. Green, Zhenyue Hao & Tak W. Mak
Nature Reviews Molecular Cell Biology 9, 532–542
(July 2008); doi:10.1038/nrm2434
| Summary | Full Text (HTML / PDF) |

review
Mitochondrial fragmentation in neurodegeneration
Andrew B. Knott, Guy Perkins, Robert Schwarzenbacher & Ella Bossy-Wetzel
Nature Reviews Neuroscience 9, 505–518
(July 2008); doi:10.1038/nrn2417
| Summary | Full Text (HTML / PDF) |

letter
Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia
Aline Bozec et al.
Nature 454, 221–225
(10 July 2008); doi:10.1038/nature07019
| Summary | Full Text (HTML / PDF) |

article
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
Emmelie Å Jansson et al.
Nature Chemical Biology 4, 411–417
(July 2008); doi:10.1038/nchembio.92
| Summary | Full Text (HTML / PDF) |

review
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Mark W. Dewhirst, Yiting Cao & Benjamin Moeller
Nature Reviews Cancer 8, 425–437
(June 2008); doi:10.1038/nrc2397
| Summary | Full Text (HTML / PDF) |

article
Regulation of autophagy by cytoplasmic p53
Ezgi Tasdemir et al.
Nature Cell Biology 10, 676–687
(June 2008); doi:10.1038/ncb1730
| Summary | Full Text (HTML / PDF) |

news and views
p53: The Janus of autophagy?
Beth Levine & John Abrams
Nature Cell Biology 10, 637–639
(June 2008); doi:10.1038/ncb0608-637
| Full Text (HTML / PDF) |

article
Real-time imaging of the intracellular glutathione redox potential
Marcus Gutscher et al.
Nature Methods 5, 553–559
(June 2008); doi:10.1038/nmeth.1212
| Summary | Full Text (HTML / PDF) |

article
Metal swap between Zn7-metallothionein-3 and amyloid-β–Cu protects against amyloid-β toxicity
Gabriele Meloni et al.
Nature Chemical Biology 4, 366–372
(June 2008); doi:10.1038/nchembio.89
| Summary | Full Text (HTML / PDF) |

letter
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
Claudine Kraft, Anna Deplazes, Marc Sohrmann & Matthias Peter
Nature Cell Biology 10, 602–610
(May 2008); doi:10.1038/ncb1723
| Summary | Full Text (HTML / PDF) |

news and views
Starved cells eat ribosomes
Hitoshi Nakatogawa & Yoshinori Ohsumi
Nature Cell Biology 10, 505–507
(May 2008); doi:10.1038/ncb0508-505
| Full Text (HTML / PDF) |

review
Reconciling the chemistry and biology of reactive oxygen species
Christine C Winterbourn
Nature Chemical Biology 5, 278–286
(May 2008); doi:10.1038/nchembio.85
| Summary | Full Text (HTML / PDF) |

review
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
Charles N. Serhan, Nan Chiang & Thomas E. Van Dyke
Nature Reviews Immunology 8, 349–361
(May 2008); doi:10.1038/nri2294
| Summary | Full Text (HTML / PDF) |

letter
Functional interaction between FOXO3a and ATM regulates DNA damage response
Wen-Bin Tsai, Young Min Chung, Yoko Takahashi, Zhaohui Xu & Mickey C.-T. Hu
Nature Cell Biology 10, 460–467
(April 2008); doi:10.1038/ncb1709
| Summary | Full Text (HTML / PDF) |

letter
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
R. Grace Zhai, Fan Zhang, P. Robin Hiesinger, Yu Cao, Claire M. Haueter & Hugo J. Bellen
Nature 452, 887–891
(17 April 2008); doi:10.1038/nature06721
| Summary | Full Text (HTML / PDF) |

review
The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K–Akt–mTOR signalling pathway
Nicholas J. Buchkovich, Yongjun Yu, Carisa A. Zampieri & James C. Alwine
Nature Reviews Microbiology 6, 266–275
(April 2008); doi:10.1038/nrmicro1855
| Summary | Full Text (HTML / PDF) |

review
The role of oxygen availability in embryonic development and stem cell function
M. Celeste Simon & Brian Keith
Nature Reviews Molecular Cell Biology 9, 285–296
(April 2008); doi:10.1038/nrm2354
| Summary | Full Text (HTML / PDF) |

article
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses
Sofia Papadia et al.
Nature Neuroscience 11, 476–487
(April 2008); doi:10.1038/nn2071
| Summary | Full Text (HTML / PDF) |

news and views
NMDA receptor activity regulates transcription of antioxidant pathways
Stuart A Lipton
Nature Neuroscience 11, 381–382
(April 2008); doi:10.1038/nn0408-381
| Full Text (HTML / PDF) |

review
Hypoxia and metabolism: Hypoxia, DNA repair and genetic instability
Robert G. Bristow & Richard P. Hill
Nature Reviews Cancer 8, 180–192
(March 2008); doi:10.1038/nrc2344
| Summary | Full Text (HTML / PDF) |

article
Direct regulation of TWIST by HIF-1α promotes metastasis
Muh-Hwa Yang et al.
Nature Cell Biology 10, 295–305
(March 2008); doi:10.1038/ncb1691
| Summary | Full Text (HTML / PDF) |

news and views
A hypoxic twist in metastasis
Héctor Peinado & Amparo Cano
Nature Cell Biology 10, 253–254
(March 2008); doi:10.1038/ncb0308-253
| Full Text (HTML / PDF) |

letter
Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint
Edward Owusu-Ansah, Amir Yavari, Sudip Mandal & Utpal Banerjee
Nature Genetics 40, 356–361
(March 2008); doi:10.1038/ng.2007.50
| Summary | Full Text (HTML / PDF) |

letter
Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint
Mariarosaria Musarò, Laura Ciapponi, Barbara Fasulo, Maurizio Gatti & Giovanni Cenci
Nature Genetics 40, 362–366
(March 2008); doi:10.1038/ng.2007.64
| Summary | Full Text (HTML / PDF) |

letter
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
Zoltan Arany et al.
Nature 451, 1008–1012
(21 February 2008); doi:10.1038/nature06613
| Summary | Full Text (HTML / PDF) |

letter
Oxidative damage-induced inflammation initiates age-related macular degeneration
Joe G Hollyfield et al.
Nature Medicine 14, 194–198
(February 2008); doi:10.1038/nm1709
| Summary | Full Text (HTML / PDF) |

review
The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
Jon O. Lundberg, Eddie Weitzberg & Mark T. Gladwin
Nature Reviews Drug Discovery 7, 156–167
(February 2008); doi:10.1038/nrd2466
| Summary | Full Text (HTML / PDF) |

review
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun & Lina M. Obeid
Nature Reviews Molecular Cell Biology 9, 139–150
(February 2008); doi:10.1038/nrm2329
| Summary | Full Text (HTML / PDF) |

scientific report
Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation
Noritaka Yasuda et al.
EMBO Reports 9, 179–186
(February 2008); doi:10.1038/sj.embor.7401157
| Summary | Full Text (HTML / PDF) |

letter
Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
Edward J. Miller et al.
Nature 451, 578–582
(31 January 2008); doi:10.1038/nature06504
| Summary | Full Text (HTML / PDF) |

letter
DBC1 is a negative regulator of SIRT1
Ja-Eun Kim, Junjie Chen & Zhenkun Lou
Nature 451, 583–586
(31 January 2008); doi:10.1038/nature06500
| Summary | Full Text (HTML / PDF) |

letter
Negative regulation of the deacetylase SIRT1 by DBC1
Wenhui Zhao, Jan-Philipp Kruse, Yi Tang, Sung Yun Jung, Jun Qin & Wei Gu
Nature 451, 587–590
(31 January 2008); doi:10.1038/nature06515
| Summary | Full Text (HTML / PDF) |

article
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
Julián Aragonés et al.
Nature Genetics 40, 170–180
(February 2008); doi:10.1038/ng.2007.62
| Summary | Full Text (HTML / PDF) |

news and views
Hypoxic reprogramming
Daniel P Kelly
Nature Genetics 40, 132–134
(February 2008); doi:10.1038/ng0208-132
| Full Text (HTML / PDF) |

perspective
The interplay between MYC and HIF in cancer
Chi V. Dang, Jung-whan Kim, Ping Gao & Jason Yustein
Nature Reviews Cancer 8, 51–56
(January 2008); doi:10.1038/nrc2274
| Summary | Full Text (HTML / PDF) |

news and views
Redox rescues virus from ER trap
Christoph J. Burckhardt & Urs F. Greber
Nature Cell Biology 10, 9–11
(January 2008); doi:10.1038/ncb0108-9
| Summary | Full Text (HTML / PDF) |

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