Research library: Structures
2003: December | November
| October | October
| September | August
| July | June
| May | April
| March | February
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Other Years: 2002 |2004 | 2005 | 2006 | 2007 | 2008
December
article
Cellular stabilization of the melatonin rhythm enzyme induced by nonhydrolyzable phosphonate incorporation
Weiping Zheng, Zhongsen Zhang, Surajit Ganguly, Joan L Weller, David C Klein and Philip A Cole
Nature Structural Biology 10, 1054–1057
(December 2003); doi:10.1038/nsb1005
| Abstract | Full Text (HTML/PDF) |
article
Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor
Louis Renault, Bernard Guibert and Jacqueline Cherfils
Nature 426, 525–530
(04 December 2003); doi:10.1038/nature02197
| Abstract | Full Text (HTML / PDF) |
November
article
An atypical haem in the cytochrome b6f complex
David Stroebel, Yves Choquet, Jean-Luc Popot and Daniel Picot
Nature 426, 413–418
(27 November 2003); doi:10.1038/nature02155
| Abstract | Full Text (HTML / PDF) |
news and views
Structural biology: Dual approach to a light problem
Werner Kühlbrandt
Nature 426, 399–400
(27 November 2003); doi:10.1038/426399a
| Full Text (HTML / PDF) |
article
The structure and binding mode of interleukin-18
Zenichiro Kato, JunGoo Jee, Hiroaki Shikano, Masaki Mishima, Izuru Ohki, Hidenori Ohnishi, Ailian Li, Kazuyuki Hashimoto, Eiji Matsukuma, Kentaro Omoya, Yutaka Yamamoto, Teruyo Yoneda, Takane Hara, Naomi Kondo & Masahiro Shirakawa
Nature Structural Biology 10, 966–971
(November 2003); doi:10.1038/nsb993
| Abstract | Full Text (HTML / PDF) |
article
Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination
Jijie Chai, Nieng Yan, Jun R. Huh, Jia-Wei Wu, Wenyu Li, Bruce A. Hay and Yigong Shi
Nature Structural Biology 10, 892–898
(November 2003); doi:10.1038/nsb989
| Abstract | Full Text (HTML/PDF) |
article
Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
Wei Feng, Yawei Shi, Ming Li and Mingjie Zhang
Nature Structural Biology 10, 972–978
(November 2003); doi:10.1038/nsb992
| Abstract | Full Text (HTML/PDF) |
article
Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation
Bin Y Qin, Cheng Liu, Suvana S Lam, Hema Srinath, Rachel Delston, John J Correia, Rik Derynck and Kai Lin
Nature Structural Biology 10, 913–921
(November 2003); doi:10.1038/nsb1002
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article
X-ray crystal structure of IRF-3 and its functional implications
Kiyohiro Takahasi, Nobuo N Suzuki, Masataka Horiuchi, Mitsuaki Mori, Wakako Suhara, Yasutaka Okabe, Yukiko Fukuhara, Hiroaki Terasawa, Shizuo Akira, Takashi Fujita and Fuyuhiko Inagaki
Nature Structural Biology 10, 922–927
(November 2003); doi:10.1038/nsb1001
| Abstract | Full Text (HTML/PDF) |
news and views
The nuts and bolts of IRF structure
Aristidis Moustakas and Carl-Henrik Heldin
Nature Structural Biology 10, 874–876
(November 2003); doi:10.1038/nsb1103-874
| Full Text (HTML/PDF) |
article
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
Eva Pebay-Peyroula, Cécile Dahout-Gonzalez, Richard Kahn, Véronique Trézéguet, Guy J.-M. Lauquin and Gérard Brandolin
Nature 426, 39–44
(06 November 2003); doi:10.1038/nature02056
| Abstract | Full Text (HTML / PDF) |
letters to nature
Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor
Isabelle M. L. Billas, Thomas Iwema, Jean-Marie Garnier, André Mitschler, Natacha Rochel and Dino Moras
Nature 426, 91–96
(06 November 2003); doi:10.1038/nature02112
| First Paragraph | Full Text (HTML / PDF) |
article
Structural determinants of SecB recognition by SecA in bacterial protein translocation
Jiahai Zhou and Zhaohui Xu
Nature Structural Biology 10, 942–947
(November 2003); doi:10.1038/nsb980
| Abstract | Full Text (HTML/PDF) |
October
letters to nature
Bone recognition mechanism of porcine osteocalcin from crystal structure
Quyen Q. Hoang, Frank Sicheri, Andrew J. Howard and Daniel S. C. Yang
Nature 425, 977–980
(30 October 2003); doi:10.1038/nature02079
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article
Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element
Michael J Giffin, James C Stroud, Darren L Bates, Konstanze D von Koenig, John Hardin and Lin Chen
Nature Structural Biology 10, 800–806
(October 2003); doi:10.1038/nsb981
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article
The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D
Christopher A Love, Karl Harlos, Nasim Mavaddat, Simon J Davis, David I Stuart, E Yvonne Jones and Robert M Esnouf
Nature Structural Biology 10, 843–848
(October 2003); doi:10.1038/nsb977
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article
Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains
Byron DeLaBarre and Axel T Brunger
Nature Structural Biology 10, 856–863
(October 2003); doi:10.1038/nsb972
| Abstract | Full Text (HTML/PDF) |
article
An asymmetric NFAT1 dimer on a pseudo-palindromic kB-like DNA site
Lei Jin, Piotr Sliz, Lin Chen, Fernando Macián, Anjana Rao, Patrick G Hogan and Stephen C Harrison
Nature Structural Biology 10, 807–811
(October 2003); doi:10.1038/nsb975
| Abstract | Full Text (HTML/PDF) |
article
All-trans retinoic acid is a ligand for the orphan nuclear receptor RORβ
Catherine Stehlin-Gaon, Dominica Willmann, Denis Zeyer, Sarah Sanglier, Alain Van Dorsselaer, Jean-Paul Renaud, Dino Moras and Roland Schüle
Nature Structural Biology 10, 820–825
(October 2003); doi:10.1038/nsb979
| Abstract | Full Text (HTML/PDF) |
September
letters to nature
A structural state of the myosin V motor without bound nucleotide
Pierre-Damien Coureux, Amber L. Wells, Julie Ménétrey, Christopher M. Yengo, Carl A. Morris, H. Lee Sweeney and Anne Houdusse
Nature 425, 419–423
(25 September 2003); doi:10.1038/nature01927
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide
Kenneth C. Holmes, Isabel Angert, F. Jon Kull, Werner Jahn and Rasmus R. Schröder
Nature 425, 423–427
(25 September 2003); doi:10.1038/nature02005
| First Paragraph | Full Text (HTML / PDF) |
perspectives
Epac: a new cAMP target and new avenues in cAMP research
Johannes L. Bos
Nature Reviews Molecular Cell Biology 4, 733–738
(September 2003); doi:10.1038/nrm1197
| Abstract | Full Text (HTML / PDF) |
news and views
Tag, you're degraded
Evelyn Jabri
Nature Structural Biology 10, 676
(September 2003); doi:10.1038/nsb0903-676
| Full Text (HTML/PDF) |
letters to nature
Structural basis for modulation and agonist specificity of HCN pacemaker channels
William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson and Eric Gouaux
Nature 425, 200–205
(11 September 2003); doi:10.1038/nature01922
| First Paragraph | Full Text (HTML / PDF) |
article
Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity
Catherine E Fitzgerald, Sangita B Patel, Joseph W Becker, Patricia M Cameron, Dennis Zaller, Vasilis Bill Pikounis, Stephen J O'Keefe and Giovanna Scapin
Nature Structural Biology 10, 764–769
(September 2003); doi:10.1038/nsb949
| Abstract | Full Text (HTML/PDF) |
letters to nature
Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules
Byung-Je Sung, Kwang Yeon Hwang, Young Ho Jeon, Jae Il Lee, Yong-Seok Heo, Jin Hwan Kim, Jinho Moon, Jung Min Yoon, Young-Lan Hyun, Eunmi Kim, Sung Jin Eum, Sam-Yong Park, Jie-Oh Lee, Tae Gyu Lee, Seonggu Ro and Joong Myung Cho
Nature 425, 98–102
(04 September 2003); doi:10.1038/nature01914
| First Paragraph | Full Text (HTML / PDF) |
article
Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor
Benjamin E. Willcox, Leonard M. Thomas and Pamela J. Bjorkman
Nature Immunology 4, 913–919
(September 2003); doi:10.1038/ni961
| Abstract | Full Text (HTML/PDF) |
article
Pulling geometry defines the mechanical resistance of a β-sheet protein
David J. Brockwell, Emanuele Paci, Rebecca C. Zinober, Godfrey S. Beddard, Peter D. Olmsted, D. Alastair Smith, Richard N. Perham and Sheena E. Radford
Nature Structural Biology 10, 731–737
(September 2003); doi:10.1038/nsb968
| Abstract | Full Text (HTML/PDF) |
article
The mechanical stability of ubiquitin is linkage dependent
Mariano Carrion-Vazquez, Hongbin Li, Hui Lu, Piotr E. Marszalek, Andres F. Oberhauser and Julio M. Fernandez
Nature Structural Biology 10, 738–743
(September 2003); doi:10.1038/nsb965
| Abstract | Full Text (HTML/PDF) |
news and views
Finding a protein's Achilles heel
Andreas Matouschek and Carlos Bustamante
Nature Structural Biology 10, 674–676
(September 2003); doi:10.1038/nsb0903-674
| Full Text (HTML/PDF) |
August
article
Recognition of accessory protein motifs by the γ-adaptin ear domain of GGA3
Gregory J. Miller, Rafael Mattera, Juan S. Bonifacino and James H. Hurley
Nature Structural Biology 10, 599–606
(August 2003); doi:10.1038/nsb953
| Abstract | Full Text (HTML/PDF) |
article
Structural basis for binding of accessory proteins by the appendage domain of GGAs
Brett M. Collins, Gerrit J. K. Praefcke, Margaret S. Robinson and David J. Owen
Nature Structural Biology 10, 607–613
(August 2003); doi:10.1038/nsb955
| Abstract | Full Text (HTML/PDF) |
news and views
The long and short of adaptor appendages
Christine Knuehl and Frances M Brodsky
Nature Structural Biology 10, 580–582
(August 2003); doi:10.1038/nsb0803-580
| Full Text (HTML/PDF) |
letters to nature
Complex between nidogen and laminin fragments reveals a paradigmatic β-propeller interface
Junichi Takagi , Yuting Yang , Jin-huan Liu, Jia-huai Wang and Timothy A. Springer
Nature 424, 969–974
(21 August 2003); doi:10.1038/nature01873
| First Paragraph | Full Text (HTML / PDF) |
article
Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster
Min-Sung Kim, Minji Byun and Byung-Ha Oh
Nature Immunology 4, 787–793
(August 2003); doi:10.1038/ni952
| Abstract | Full Text (HTML/PDF) |
article
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex
Sanjay C. Panchal, Donald A. Kaiser, Eduardo Torres, Thomas D. Pollard and Michael K. Rosen
Nature Structural Biology 10, 591–598
(August 2003); doi:10.1038/nsb952
| Abstract | Full Text (HTML/PDF) |
news and views
Now, swing your partner! 3D-domain switching of WASP activates Arp2/3 complex
Sarah E. Hitchcock-DeGregori
Nature Structural Biology 10, 583–584
(August 2003); doi:10.1038/nsb0803-583
| Full Text (HTML/PDF) |
article
Structural basis for partial agonist action at ionotropic glutamate receptors
Rongsheng Jin, Tue G. Banke, Mark L. Mayer, Stephen F. Traynelis and Eric Gouaux
Nature Neuroscience 6, 803–810
(August 2003); doi:10.1038/nn1091
| Abstract | Full Text (HTML/PDF) |
news and views
Crystallizing our understanding of partial agonists
David S. Weiss and Yongchang Chang
Nature Neuroscience 6, 788–789
(August 2003); doi:10.1038/nn0803-788
| Full Text (HTML/PDF) |
news and views
Pulling the calcium trigger
Brian D. Sykes
Nature Structural Biology 10, 588–589
(August 2003); doi:10.1038/nsb0803-588
| Full Text (HTML/PDF) |
article
Opioid receptor random mutagenesis reveals a mechanism for G protein-coupled receptor activation
Fabien M Décaillot, Katia Befort, Dominique Filliol, ShiYi Yue, Philippe Walker and Brigitte L Kieffer
Nature Structural Biology 10, 629–636
(August 2003); doi:10.1038/nsb950
| Abstract | Full Text (HTML/PDF) |
July
letters to nature
Crystal structure of human cytochrome P450 2C9 with bound warfarin
Pamela A. Williams, Jose Cosme, Alison Ward, Hayley C. Angove, Dijana Matak Vinkovic and Harren Jhoti
Nature 424, 464–468
(24 July 2003); doi:10.1038/nature01862
| First Paragraph | Full Text (HTML / PDF) |
article
Structural basis for negative regulation of hypoxia-inducible factor-1α by CITED2
Steven J. Freedman, Zhen-Yu J. Sun, Andrew L. Kung, Dennis S. France, Gerhard Wagner and Michael J. Eck
Nature Structural Biology 10, 504–512
(July 2003); doi:10.1038/nsb936
| Abstract | Full Text (HTML/PDF) |
news and views
ExCITED about HIF
Shoumo Bhattacharya and Peter J. Ratcliffe
Nature Structural Biology 10, 501–503
(July 2003); doi:10.1038/nsb0703-501
| Full Text (HTML/PDF) |
article
Structural and functional insights into PINCH LIM4 domain-mediated integrin signaling
Algirdas Velyvis, Julia Vaynberg, Yanwu Yang, Olga Vinogradova, Yongjun Zhang, Chuanyue Wu and Jun Qin
Nature Structural Biology 10, 558–564
(July 2003); doi:10.1038/nsb938
| Abstract | Full Text (HTML/PDF) |
article
A structural basis for immunodominant human T cell receptor recognition
Guillaume B E Stewart-Jones, Andrew J McMichael, John I Bell, David I Stuart and E Yvonne Jones
Nature Immunology 4, 657–663
(July 2003); doi:10.1038/ni942
| Abstract | Full Text (HTML/PDF) |
news and views
The problem of plain vanilla peptides
Mark M Davis
Nature Immunology 4, 649–650
(July 2003); doi:10.1038/ni0703-649
| Full Text (HTML/PDF) |
article
Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Elisabetta Sabini, Stephan Ort, Christian Monnerjahn, Manfred Konrad and Arnon Lavie
Nature Structural Biology 10, 513–519
(July 2003); doi:10.1038/nsb942
| Abstract | Full Text (HTML/PDF) |
article
Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
Soichi Takeda, Atsuko Yamashita, Kayo Maeda and Yuichiro Maéda
Nature 424, 35–41
(03 July 2003); doi:10.1038/nature01780
| Abstract | Full Text (HTML / PDF) |
article
A molecular switch between alternative conformational states in the complex of Ran and importin β1
Reinat Nevo, Cordula Stroh, Ferry Kienberger, David Kaftan, Vlad Brumfeld, Michael Elbaum, Ziv Reich and Peter Hinterdorfer
Nature Structural Biology 10, 553–557
(July 2003); doi:10.1038/nsb940
| Abstract | Full Text (HTML/PDF) |
June
article
Structural insights into the catalytic mechanism of cyclophilin A
Bruce R Howard, Felix F Vajdos, Su Li, Wesley I Sundquist and Christopher P Hill
Nature Structural Biology 10, 475–481
(June 2003); doi:10.1038/nsb927
| Abstract | Full Text (HTML/PDF) |
letters to nature
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
Annette Salmeen, Jannik N. Andersen, Michael P. Myers, Tzu-Ching Meng, John A. Hinks, Nicholas K. Tonks and David Barford
Nature 423, 769–773
(12 June 2003); doi:10.1038/nature01680
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B
Rob L. M. van Montfort, Miles Congreve, Dominic Tisi, Robin Carr and Harren Jhoti
Nature 423, 773–777
(12 June 2003); doi:10.1038/nature01681
| First Paragraph | Full Text (HTML / PDF) |
article
Redox-sensitive extracellular gates formed by auxiliary β subunits of calcium-activated potassium channels
Xu-Hui Zeng, Xiao-Ming Xia and Christopher J Lingle
Nature Structural Biology 10, 448–454
(June 2003); doi:10.1038/nsb932
| Abstract | Full Text (HTML/PDF) |
article
Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc
Andrew B. Herr, Edward R. Ballister and Pamela J. Bjorkman
Nature 423, 614–620
(05 June 2003); doi:10.1038/nature01685
| Abstract | Full Text (HTML / PDF) |
May
article
Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen
Dawei Li, Rui Zhao, Wayne Lilyestrom, Dahai Gai, Rongguang Zhang, James A. DeCaprio, Ellen Fanning, Andrzej Jochimiak, Gerda Szakonyi and Xiaojiang S. Chen
Nature 423, 512–518
(29 May 2003); doi:10.1038/nature01691
| Summary | Full Text (HTML / PDF) |
letters to nature
Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors
Zhulun Wang, Gérard Benoit, Jinsong Liu, Srividya Prasad, Piia Aarnisalo, Xiaohong Liu, Haoda Xu, Nigel P. C. Walker and Thomas Perlmann
Nature 423, 555–560
(29 May 2003); doi:10.1038/nature01645
| First Paragraph | Full Text (HTML / PDF) |
article
Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
Ho Min Kim, Kyung Sook Yu, Mi Eun Lee, Dong Ryeol Shin, Young Sang Kim, Sang-Gi Paik, Ook Joon Yoo, Hayyoung Lee and Jie-Oh Lee
Nature Structural Biology 10, 342–348
(May 2003); doi:10.1038/nsb925
| Abstract | Full Text (HTML/PDF) |
article
Molecular mechanism of membrane recruitment of GGA by ARF in lysosomal protein transport
Tomoo Shiba, Masato Kawasaki, Hiroyuki Takatsu, Terukazu Nogi, Naohiro Matsugaki, Noriyuki Igarashi, Mamoru Suzuki, Ryuichi Kato, Kazuhisa Nakayama and Soichi Wakatsuki
Nature Structural Biology 10, 386–393
(May 2003); doi:10.1038/nsb920
| Abstract | Full Text (HTML/PDF) |
article
Calpain silencing by a reversible intrinsic mechanism
Tudor Moldoveanu, Christopher M. Hosfield, Daniel Lim, Zongchao Jia and Peter L. Davies
Nature Structural Biology 10, 371–378
(May 2003); doi:10.1038/nsb917
| Abstract | Full Text (HTML/PDF) |
article
X-ray structure of a voltage-dependent K+ channel
Youxing Jiang, Alice Lee, Jiayun Chen, Vanessa Ruta, Martine Caden, Brian T. Chait and Roderick Mackinnon
Nature 423, 33–41
(1 May 2003); doi:10.1038/nature01580
| Abstract | Full Text (HTML / PDF) |
article
The principle of gating charge movement in a voltage-dependent K+ channel
Youxing Jiang, Vanessa Ruta, Jiayun Chen, Alice Lee and Roderick Mackinnon
Nature 423, 42–48
(1 May 2003); doi:10.1038/nature01581
| Abstract | Full Text (HTML / PDF) |
news and views
Structural biology: Life's transistors
Fred J. Sigworth
Nature 423, 21–22
(1 May 2003); doi:10.1038/423021a
| Full Text (HTML / PDF) |
review article
Ligand–receptor binding revealed by the TNF family member TALL-1
Yingfang Liu, Xia Hong, John Kappler, Ling Jiang, Rongguang Zhang, Liangguo Xu, Cheol-Ho Pan Wesley E. Martin, Robert C. Murphy, Hong-Bing Shu, Shaodong Dai and Gongyi Zhang
Nature 423, 49–56
(1 May 2003); doi:10.1038/nature01543
| Summary | Full Text (HTML / PDF) |
April
news and views
Cancer: Escape from inhibition
Sara A. Courtneidge
Nature 422, 827–828
(24 April 2003); doi:10.1038/422827a
| Full Text (HTML / PDF) |
letters to nature
Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2
Aidong Han, Fan Pan, James C. Stroud, Hong-Duk Youn, Jun O. Liu and Lin Chen
Nature 422, 730–734
(17 April 2003); doi:10.1038/nature01555
| First Paragraph | Full Text (HTML / PDF) |
article
A novel protein-mineral interface
Dmitriy Alexeev, Haizhong Zhu, Maolin Guo, Weiqing Zhong, Dominic J.B. Hunter, Weiping Yang, Dominic J. Campopiano and Peter J. Sadler
Nature Structural Biology 10, 297–302
(April 2003); doi:10.1038/nsb903
| Abstract | Full Text (HTML/PDF) |
news and views
Iron acquisition: straight up and on the rocks?
Alison Butler
Nature Structural Biology 10, 240–241
(April 2003); doi:10.1038/nsb0403-240
| Full Text (HTML/PDF) |
news and views
Two-stepping with E1
Andrew P. VanDemark and Christopher P. Hill
Nature Structural Biology 10, 244–246
(April 2003); doi:10.1038/nsb0403-244
| Full Text (HTML/PDF) |
March
article
Three-dimensional structural dynamics of myosin V by single-molecule fluorescence polarization
Joseph N. Forkey, Margot E. Quinlan, M. Alexander Shaw, John E. T. Corrie and Yale E. Goldman
Nature 422, 399–404
(27 March 2003); doi:10.1038/nature01529
| Summary | Full Text (HTML / PDF) |
letters to nature
Hidden complexity in the mechanical properties of titin
Philip M. Williams, Susan B. Fowler, Robert B. Best, José Luis Toca-Herrera, Kathryn A. Scott, Annette Steward and Jane Clarke
Nature 422, 446–449
(27 March 2003); doi:10.1038/nature01517
| First Paragraph | Full Text (HTML / PDF) |
article
Crystal structure of a MARCKS peptide containing the calmodulin-binding domain in complex with Ca2+-calmodulin
Emiko Yamauchi, Toru Nakatsu, Mamoru Matsubara, Hiroaki Kato and Hisaaki Taniguchi
Nature Structural Biology 10, 226–231
(March 2003); doi:10.1038/nsb900
| Abstract | Full Text (HTML/PDF) |
letters to nature
Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8
Helen Walden, Michael S. Podgorski and Brenda A. Schulman
Nature 422, 330–334
(20 March 2003); doi:10.1038/nature01456
| First Paragraph | Full Text (HTML / PDF) |
article
Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases
Tracy A. Young, Benedicte Delagoutte, James A. Endrizzi, Arnold M. Falick and Tom Alber
Nature Structural Biology 10, 168–174
(March 2003); doi:10.1038/nsb897
| Abstract | Full Text (HTML/PDF) |
February
news and views
Molecular chaperones: Plugging the transport gap
R. John Ellis
Nature 421, 801–802
(20 February 2003); doi:10.1038/421801a
| Full Text (HTML / PDF) |
letters to nature
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
Hyun-Soo Cho, Karen Mason, Kasra X. Ramyar, Ann Marie Stanley, Sandra B. Gabelli, Dan W. Denney Jr and Daniel J. Leahy
Nature 421, 756–760
(13 February 2003); doi:10.1038/nature01392
| First Paragraph | Full Text (HTML / PDF) |
letters to nature
Structure and catalytic mechanism of the human histone methyltransferase SET7/9
Bing Xiao, Chun Jing, Jonathan R. Wilson, Philip A. Walker, Nishi Vasisht, Geoff Kelly, Steven Howell, Ian A. Taylor, G. Michael Blackburn and Steven J. Gamblin
Nature 421, 652–656
(06 February 2003); doi:10.1038/nature01378
| First Paragraph | Full Text (HTML / PDF) |
January
letters to nature
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex
Ramanathan Natesh, Sylva L. U. Schwager, Edward D. Sturrock and K. Ravi Acharya
Nature 421, 551–554
(30 January 2003); doi:10.1038/nature01370
| First Paragraph | Full Text (HTML / PDF) |
article
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
Gürol M. Süel, Steve W. Lockless, Mark A. Wall and Rama Ranganathan
Nature Structural Biology 10, 59–69
(January 2003); doi:10.1038/nsb881
| Abstract | Full Text (HTML/PDF) |
article
Automated design of specificity in molecular recognition
James J. Havranek and Pehr B. Harbury
Nature Structural Biology 10, 45–52
(January 2003); doi:10.1038/nsb877
| Abstract | Full Text (HTML/PDF) |
article
Angiopoietins have distinct modular domains essential for receptor binding, dimerization and superclustering
Samuel Davis, Nick Papadopoulos, Thomas H. Aldrich, Peter C. Maisonpierre, Tammy Huang, Lubomir Kovac, April Xu, Raymond Leidich, Elzbieta Radziejewska, Ashique Rafique, Judah Goldberg, Vivek Jain, Kevin Bailey, Margaret Karow, Jim Fandl, Steven J. Samuelsson, Ella Ioffe, John S. Rudge, Thomas J. Daly, Czeslaw Radziejewski and George D. Yancopoulos
Nature Structural Biology 10, 38–44
(January 2003); doi:10.1038/nsb880
| Abstract | Full Text (HTML/PDF) |
article
Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog
Hanne B. Rasmussen, Sven Branner, Finn C. Wiberg and Nicolai Wagtmann
Nature Structural Biology 10, 19–25
(January 2003); doi:10.1038/nsb882
| Abstract | Full Text (HTML/PDF) |
news and views
First bite
Mark D. Gorrell
Nature Structural Biology 10, 3–5
(January 2003); doi:10.1038/nsb0103-3
| Full Text (HTML/PDF) |
article
Structure and regulation of the cAMP-binding domains of Epac2
Holger Rehmann, Balaji Prakash, Eva Wolf, Alma Rueppel, Johan de Rooij,
Johannes L. Bos and Alfred Wittinghofer
Nature Structural Biology 10, 26–32
(January 2003); doi:10.1038/nsb878
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