Research library: Structures
2006:
December
| November
| September
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2007 | 2008
December
letter
Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity
Rongsheng Jin, Andreas Rummel, Thomas Binz and Axel T. Brunger
Nature 444, 1092–1095
(21 December 2006); doi:10.1038/nature05387
| First Paragraph | Full Text (HTML / PDF) |
letter
Structural basis of cell surface receptor recognition by botulinum neurotoxin B
Qing Chai, Joseph W. Arndt, Min Dong, William H. Tepp, Eric A. Johnson, Edwin R. Chapman and Raymond C. Stevens
Nature 444, 1096–1100
(21 December 2006); doi:10.1038/nature05411
| First Paragraph | Full Text (HTML / PDF) |
review
Membrane-protein topology
Gunnar von Heijne
Nature Reviews Molecular Cell Biology 7, 909–918
(December 2006); doi:10.1038/nrm2063
| Summary | Full Text (HTML / PDF) |
article
Large movement in the C terminus of CLC-0 chloride channel during slow gating
Ekaterina A Bykova, Xiao-Dong Zhang, Tsung-Yu Chen & Jie Zheng
Nature Structural & Molecular Biology 13, 1115–1119
(December 2006); doi:10.1038/nsmb1176
| Summary | Full Text (HTML / PDF) |
article
Conformational restriction blocks glutamate receptor desensitization
Matthew C Weston, Peter Schuck, Alokesh Ghosal, Christian Rosenmund & Mark L Mayer
Nature Structural & Molecular Biology 13, 1120–1127
(December 2006); doi:10.1038/nsmb1178
| Summary | Full Text (HTML / PDF) |
November
article
Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer
Marta Pioletti, Felix Findeisen, Greg L Hura & Daniel L Minor, Jr
Nature Structural and Molecular Biology 13, 987–995
(November 2006); doi:10.1038/nsmb1164
| Summary | Full Text (HTML / PDF) |
letter
Visualization of transient encounter complexes in protein-protein association
Chun Tang, Junji Iwahara and G. Marius Clore
Nature 444, 383–386
(16 November 2006); doi:10.1038/nature05201
| First Paragraph | Full Text (HTML / PDF) |
letter
Structure of C3b reveals conformational changes that underlie complement activity
Bert J. C. Janssen, Agni Christodoulidou, Andrew McCarthy, John D. Lambris and Piet Gros
Nature 444, 213–216
(09 November 2006); doi:10.1038/nature05172
| First Paragraph | Full Text (HTML / PDF) |
letter
Structure of C3b in complex with CRIg gives insights into regulation of complement activation
Christian Wiesmann, Kenneth J. Katschke, JianPing Yin, Karim Y. Helmy, Micah Steffek, Wayne J. Fairbrother, Scott A. McCallum, Lizette Embuscado, Laura DeForge, Philip E. Hass and Menno van Lookeren Campagne
Nature 444, 217–220
(09 November 2006); doi:10.1038/nature05263
| First Paragraph | Full Text (HTML / PDF) |
letter
The structure of complement C3b provides insights into complement activation and regulation
A. Abdul Ajees , K. Gunasekaran , John E. Volanakis , Sthanam. V. L. Narayana , Girish J. Kotwal and H. M. Krishna Murthy
Nature 444, 221–225
(09 November 2006); doi:10.1038/nature05258
| First Paragraph | Full Text (HTML / PDF) |
news and views
Immunology: Exposure of an executioner
Michael Carroll
Nature 444, 159–160
(09 November 2006); doi:10.1038/nature05307
| Full Text (HTML / PDF) |
letter
Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein
Changjiang Dong, Konstantinos Beis , Jutta Nesper, Anne L. Brunkan-LaMontagne, Bradley R. Clarke, Chris Whitfield and James H. Naismith
Nature 444, 226–229
(09 November 2006); doi:10.1038/nature05267
| First Paragraph | Full Text (HTML / PDF) |
article
A new strategy for structure determination of large proteins in solution without deuteration
Yingqi Xu, Yu Zheng, Jing-Song Fan & Daiwen Yang
Nature Methods 3, 931–937
(November 2006); doi:10.1038/nmeth938
| Summary | Full Text (HTML / PDF) |
September
article
Crystal structure of an H/ACA box ribonucleoprotein particle
Ling Li and Keqiong Ye
Nature 443, 302–307
(21 September 2006); doi:10.1038/nature05151
| Summary | Full Text (HTML / PDF) |
article
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism
Satoshi Murakami , Ryosuke Nakashima, Eiki Yamashita, Takashi Matsumoto and Akihito Yamaguchi
Nature 443, 173–179
(14 September 2006); doi:10.1038/nature05076
| Summary | Full Text (HTML / PDF) |
article
Structure of a bacterial multidrug ABC transporter
Roger J. P. Dawson and Kaspar P. Locher
Nature 443, 180–185
(14 September 2006); doi:10.1038/nature05155
| Summary | Full Text (HTML / PDF) |
letter
Structure of the insulin receptor ectodomain reveals a folded-over conformation
Neil M. McKern, Michael C. Lawrence, Victor A. Streltsov, Mei-Zhen Lou, Timothy E. Adams, George O. Lovrecz, Thomas C. Elleman, Kim M. Richards, John D. Bentley, Patricia A. Pilling, Peter A. Hoyne, Kellie A. Cartledge, Tam M. Pham, Jennifer L. Lewis, Sonia E. Sankovich, Violet Stoichevska, Elizabeth Da Silva, Christine P. Robinson, Maurice J. Frenkel, Lindsay G. Sparrow, Ross T. Fernley, V. Chandana Epa and Colin W. Ward
Nature 443, 218–221
(14 September 2006); doi:10.1038/nature05106
| First Paragraph | Full Text (HTML / PDF) |
article
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
Rupert J. Russell, Lesley F. Haire, David J. Stevens, Patrick J. Collins, Yi Pu Lin, G. Michael Blackburn, Alan J. Hay, Steven J. Gamblin and John J. Skehel
Nature 443, 45–49
(7 September 2006); doi:10.1038/nature05114
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: Antiviral drugs fit for a purpose
Ming Luo
Nature 443, 37–38
(7 September 2006); doi:10.1038/nature05003
| Full Text (HTML / PDF) |
letter
Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex
Carlos Frazão, Colin E. McVey, Mónica Amblar, Ana Barbas, Clemens Vonrhein, Cecília M. Arraiano and Maria A. Carrondoe
Nature 443, 110–114
(7 September 2006); doi:10.1038/nature05080
| Summary | Full Text (HTML / PDF) |
letter
In situ structure of the complete Treponema primitia flagellar motor
Gavin E. Murphy, Jared R. Leadbetter and Grant J. Jensen
Nature 442, 1062–1064
(31 August 2006); doi:10.1038/nature05015
| First Paragraph | Full Text (HTML / PDF) |
August
letter
An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis
Fajun Yang , Bryan W. Vought, John S. Satterlee, Amy K. Walker, Z.-Y. Jim Sun, Jennifer L. Watts, Rosalie DeBeaumont, R. Mako Saito , Sven G. Hyberts, Shaosong Yang , Christine Macol , Lakshmanan Iyer, Robert Tjian, Sander van den Heuvel , Anne C. Hart, Gerhard Wagner and Anders M. Näär
Nature 442, 700–704
(10 August 2006); doi:10.1038/nature04942
| First Paragraph | Full Text (HTML / PDF) |
July
letter
TBC-domain GAPs for Rab GTPases accelerate GTP hydrolysis by a dual-finger mechanism
Xiaojing Pan, Sudharshan Eathiraj, Mary Munson and David G. Lambright
Nature 442, 303–306
(20 July 2006); doi:10.1038/nature04847
| First Paragraph | Full Text (HTML / PDF) |
letter
Atom-by-atom analysis of global downhill protein folding
Mourad Sadqi, David Fushman and Victor Muñoz
Nature 442, 317–321
(20 July 2006); doi:10.1038/nature04859
| First Paragraph | Full Text (HTML / PDF) |
letter
Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography
Jun Liu, Dianne W. Taylor, Elena B. Krementsova, Kathleen M. Trybus and Kenneth A. Taylor
Nature 442, 208–211
(13 July 2006); doi:10.1038/nature04719
| First Paragraph | Full Text (HTML / PDF) |
letter
The cargo-binding domain regulates structure and activity of myosin 5
Kavitha Thirumurugan, Takeshi Sakamoto, John A. Hammer III, James R. Sellers and Peter J. Knight
Nature 442, 212–215
(13 July 2006); doi:10.1038/nature04865
| First Paragraph | Full Text (HTML / PDF) |
letter
Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF
Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis and Dinshaw J. Patel
Nature 442, 91–95
(06 July 2006); doi:10.1038/nature04802
| First Paragraph | Full Text (HTML / PDF) |
June
letter
Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch
Alexander Serganov, Anna Polonskaia, Anh Tuân Phan, Ronald R. Breaker and Dinshaw J. Patel
Nature 441, 1167–1171
(29 June 2006); doi:10.1038/nature04740
| First Paragraph | Full Text (HTML / PDF) |
article
Distribution and three-dimensional structure of AIDS virus envelope spikes
Ping Zhu, Jun Liu, Julian Bess Jr, Elena Chertova, Jeffrey D. Lifson, Henry Grisé, Gilad A. Ofek, Kenneth A. Taylor and Kenneth H. Roux
Nature 441, 847–852
(15 June 2006); doi:10.1038/nature04817
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: Images from the surface of HIV
Dennis R. Burton
Nature 441, 817–818
(15 June 2006); doi:10.1038/441817a
| Full Text (HTML / PDF) |
review article
Interpreting the protein language using proteomics
Ole N. Jensen
Nature Reviews Molecular Cell Biology 7, 391–403
(June 2006); doi:10.1038/nrm1939
| Summary | Full Text (HTML / PDF) |
May
news and views
RNA interference below the immune radar
Mouldy Sioud
Nature Biotechnology 24, 521–522
(May 2006); doi:10.1038/nbt0506–521
| Summary | Full Text (HTML / PDF) |
April
review article
The therapeutic potential of monoamine oxidase inhibitors
Moussa B. H. Youdim, Dale Edmondson and Keith F. Tipton
Nature Reviews Neuroscience 7, 295–309
(April 2006); doi:10.1038/nrn1883
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex
Maruf M. U. Ali, S. Mark Roe, Cara K. Vaughan, Phillipe Meyer, Barry Panaretou, Peter W. Piper, Chrisostomos Prodromou and Laurence H. Pearl
Nature 440, 1013–1017
(20 April 2006); doi:10.1038/nature04716
| Summary | Full Text (HTML / PDF) |
letter
Toxin-induced conformational changes in a potassium channel revealed by solid-state NMR
Adam Lange, Karin Giller, Sönke Hornig, Marie-France Martin-Eauclaire, Olaf Pongs, Stefan Becker and Marc Baldus
Nature 440, 959–962
(13 April 2006); doi:10.1038/nature04649
| First Paragraph | Full Text (HTML / PDF) |
March
letter
Atomic structure of a Na+- and K+-conducting channel
Ning Shi, Sheng Ye, Amer Alam, Liping Chen and Youxing Jiang
Nature 440, 570–574
(23 March 2006); doi:10.1038/nature04508
| First Paragraph | Full Text (HTML/PDF) |
letter
Membrane biology: Permutations of permeability
William N. Zagotta
Nature 440, 427–429
(23 March 2006); doi:10.1038/440427a
| Full Text (HTML/PDF) |
news and views
U2
Steven L Alam and Wesley I Sundquist
Nature Structural and Molecular Biology 13, 186–188
(March 2006); doi:10.1038/nsmb0306-186
| Summary | Full Text (HTML / PDF) |
article
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Satoshi Hirano, Masato Kawasaki, Hideaki Ura, Ryuichi Kato, Camilla Raiborg, Harald Stenmark and Soichi Wakatsuki
Nature Structural and Molecular Biology 13, 272–277
(March 2006); doi:10.1038/nsmb1051
| Abstract | Full Text (HTML/PDF) |
article
Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
Sangho Lee, Yien Che Tsai, Rafael Mattera, William J Smith, Michael S Kostelansky, Allan M Weissman, Juan S Bonifacino and James H Hurley
Nature Structural and Molecular Biology 13, 264–271
(March 2006); doi:10.1038/nsmb1064
| Abstract | Full Text (HTML/PDF) |
review article
Structural systems biology: modelling protein interactions
Patrick Aloy and Robert B. Russell
Nature Reviews Molecular Cell Biology 7, 188–197
(March 2006); doi:10.1038/nrm1859
| Summary | Full Text (HTML / PDF) |
article
Optimal isotope labelling for NMR protein structure determinations
Masatsune Kainosho, Takuya Torizawa, Yuki Iwashita, Tsutomu Terauchi, Akira Mei Ono and Peter Güntert
Nature 440, 52–57
(02 March 2006); doi:10.1038/nature04525
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: Designer labels
Stanley J. Opella
Nature 440, 40
(02 March 2006); doi:10.1038/440040a
| Full Text (HTML / PDF) |
letter
How guanylate-binding proteins achieve assembly-stimulated processive cleavage of GTP to GMP
Agnidipta Ghosh, Gerrit J. K. Praefcke, Louis Renault, Alfred Wittinghofer and Christian Herrmann
Nature 440, 101–104
(02 March 2006); doi:10.1038/nature04510
| First Paragraph | Full Text (HTML / PDF) |
February
letter
A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd
Nicholas F. Endres, Craig Yoshioka, Ronald A. Milligan and Ronald D. Vale
Nature 439, 875–878
(16 February 2006); doi:10.1038/nature04320
| First Paragraph | Full Text (HTML / PDF) |
letter
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB
Bomina Yu, William C. Edstrom, Jordi Benach, Yoshitomo Hamuro, Patricia C. Weber, Brian R. Gibney and John F. Hunt
Nature 439, 879–884
(16 February 2006); doi:10.1038/nature04561
| First Paragraph | Full Text (HTML / PDF) |
review article
Gating prokaryotic mechanosensitive channels
Eduardo Perozo
Nature Reviews Molecular Cell Biology 7, 109–119
(February 2006); doi:10.1038/nrm1833
| Summary | Full Text (HTML / PDF) |
article
Structural mechanism of plant aquaporin gating
Susanna Törnroth-Horsefield, Yi Wang, Kristina Hedfalk, Urban Johanson, Maria Karlsson, Emad Tajkhorshid, Richard Neutze and Per Kjellbom
Nature 439, 688–694
(09 February 2006); doi:10.1038/nature04316
| Summary | Full Text (HTML / PDF) |
letter
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state
Holger Rehmann, Joost Das, Puck Knipscheer, Alfred Wittinghofer and Johannes L. Bos
Nature 439, 625–628
(02 February 2006); doi:10.1038/nature04468
| First Paragraph | Full Text (HTML / PDF) |
January
article
Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Hubert Kettenberger, Alexander Eisenführ, Florian Brueckner, Mirko Theis, Michael Famulok and Patrick Cramer
Nature Structural and Molecular Biology 13, 44–48
(January 2006); doi:10.1038/nsmb1032
| Abstract | Full Text (HTML/PDF) |
letter
Structure of the Sec13/31 COPII coat cage
Scott M. Stagg , Cemal Gürkan, Douglas M. Fowler, Paul LaPointe, Ted R. Foss, Clinton S. Potter, Bridget Carragher and William E. Balch
Nature 439, 234–238
(12 January 2006); doi:10.1038/nature04339
| First Paragraph | Full Text (HTML / PDF) |
review article
Life of a clathrin coat: insights from clathrin and AP structures
Melissa A. Edeling, Corinne Smith and David Owen
Nature Reviews Molecular Cell Biology 7, 32–44
(January 2006); doi:10.1038/nrm1786
| Summary | Full Text (HTML / PDF) |
|
