Research library: Structures
2007:
December
| November
| October
| September
| August
| July
| June
| May
| April
| March
| February
| January
Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2008
December
article
The structural basis of calcium transport by the calcium pump
Claus Olesen et al.
Nature 450, 1036–1042
(13 December 2007); doi:10.1038/nature06418
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the sodium–potassium pump
J. Preben Morth et al.
Nature 450, 1043–1049
(13 December 2007); doi:10.1038/nature06419
| Summary | Full Text (HTML / PDF) |
letter
Crystal structure of the plasma membrane proton pump
Bjørn P. Pedersen, Morten J. Buch-Pedersen, J. Preben Morth, Michael G. Palmgren & Poul Nissen
Nature 450, 1111–1114
(13 December 2007); doi:10.1038/nature06417
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: Ion pumps made crystal clear
David C. Gadsby
Nature 450, 957–959
(13 December 2007); doi:10.1038/450957a
| Full Text (HTML / PDF) |
article
A YY1–INO80 complex regulates genomic stability through homologous recombination-based repair
Su Wu et al.
Nature Structural & Molecular Biology 14, 1165–1172
(December 2007); doi:10.1038/nsmb1332
| Summary | Full Text (HTML / PDF) |
November
letter
Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface
Xuewu Zhang, Kerry A. Pickin, Ron Bose, Natalia Jura, Philip A. Cole & John Kuriyan
Nature 450, 741–744
(29 November 2007); doi:10.1038/nature05998
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of a catalytic intermediate of the maltose transporter
Michael L. Oldham, Dheeraj Khare, Florante A. Quiocho, Amy L. Davidson & Jue Chen
Nature 450, 515–521
(22 November 2007); doi:10.1038/nature06264
| Summary | Full Text (HTML / PDF) |
article
Conformational dynamics of the KcsA potassium channel governs gating properties
Kent A Baker, Christos Tzitzilonis, Witek Kwiatkowski, Senyon Choe & Roland Riek
Nature Structural & Molecular Biology 14, 1089–1095
(November 2007); doi:10.1038/nsmb1311
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Søren G. F. Rasmussen et al.
Nature 450, 383–387
(15 November 2007); doi:10.1038/nature06325
| Summary | Full Text (HTML / PDF) |
news and views
Structural biology: A receptor unlocked
Stephen R. Sprang
Nature 450, 355–356
(15 November 2007); doi:10.1038/450355a
| Full Text (HTML / PDF) |
perspective
Mechanisms, biology and inhibitors of deubiquitinating enzymes
Kerry Routenberg Love, André Catic, Christian Schlieker and Hidde L Ploegh
Nature Chemical Biology 3, 697–705
(November 2007); doi:10.1038/nchembio.2007.43
| Summary | Full Text (HTML / PDF) |
article
Hedgehog regulates smoothened activity by inducing a conformational switch
Yun Zhao, Chao Tong & Jin Jiang
Nature 450, 252–258
(8 November 2007); doi:10.1038/nature06225
| Summary | Full Text (HTML / PDF) |
review
Common themes in the assembly and architecture of activating immune receptors
Matthew E. Call & Kai W. Wucherpfennig
Nature Reviews Immunology 7, 841–850
(November 2007); doi:10.1038/nri2186
| Summary | Full Text (HTML / PDF) |
article
Molecular driving forces determining potassium channel slow inactivation
Julio F Cordero-Morales et al.
Nature Structural & Molecular Biology 14, 1062–1069
(November 2007); doi:10.1038/nsmb1309
| Summary | Full Text (HTML / PDF) |
review
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
Kun Ping Lu & Xiao Zhen Zhou
Nature Reviews Molecular Cell Biology 8, 904–916
(November 2007); doi:10.1038/nrm2261
| Summary | Full Text (HTML / PDF) |
perspective
Inventing the dynamo machine: the evolution of the F-type and V-type ATPases
Armen Y. Mulkidjanian, Kira S. Makarova, Michael Y. Galperin & Eugene V. Koonin
Nature Reviews Microbiology 5, 892–899
(November 2007); doi:10.1038/nrmicro1767
| Summary | Full Text (HTML / PDF) |
brief communication
A monoclonal antibody for G protein-coupled receptor crystallography
Peter W Day et al.
Nature Methods 4, 927–929
(November 2007); doi:10.1038/nmeth1112
| Summary | Full Text (HTML / PDF) |
news and views
A more discerning zinc exporter
Nigel J Robinson
Nature Chemical Biology 3, 692–693
(November 2007); doi:10.1038/nchembio1107-692
| Full Text (HTML / PDF) |
October
review
Ribozymes, riboswitches and beyond: regulation of gene expression without proteins
Alexander Serganov & Dinshaw J. Patel
Nature Reviews Genetics 8, 776–790
(October 2007); doi:10.1038/nrg2172
| Summary | Full Text (HTML / PDF) |
letter
Computational design of antibody-affinity improvement beyond in vivo maturation
Shaun M Lippow, K Dane Wittrup, & Bruce Tidor
Nature Biotechnology 25, 1171–1176
(October 2007); doi:10.1038/nbt1336
| Summary | Full Text (HTML / PDF) |
news and views
No free energy lunch
Brian K Shoichet
Nature Biotechnology 25, 1109–1110
(October 2007); doi:10.1038/nbt1007-1109
| Full Text (HTML / PDF) |
article
Distinct domains of complexin I differentially regulate neurotransmitter release
Mingshan Xue et al.
Nature Structural & Molecular Biology 14, 949–958
(October 2007); doi:10.1038/nsmb1292
| Summary | Full Text (HTML / PDF) |
letter
Architectural and mechanistic insights into an EHD ATPase involved in membrane remodelling
Oliver Daumke, Richard Lundmark, Yvonne Vallis, Sascha Martens, P. Jonathan G. Butler & Harvey T. McMahon
Nature 449, 923–922
(18 October 2007); doi:10.1038/nature06173
| Summary | Full Text (HTML / PDF) |
article
The structure of bacterial ParM filaments
Albina Orlova, Ethan C Garner, Vitold E Galkin, John Heuser, R Dyche Mullins & Edward H Egelmant
Nature Structural & Molecular Biology 14, 921–926
(October 2007); doi:10.1038/nsmb1300
| Summary | Full Text (HTML / PDF) |
news and views
Sensing of DNA damage by XPC/Rad4: one protein for many lesions
Kaoru Sugasawa & Fumio Hanaoka
Nature Structural & Molecular Biology 14, 887–888
(October 2007); doi:10.1038/nsmb1007-887
| Summary | Full Text (HTML / PDF) |
letter
Mechanism of chloride interaction with neurotransmitter:sodium symporters
Elia Zomot, Annie Bendahan, Matthias Quick, Yongfang Zhao, Jonathan A. Javitch & Baruch I. Kanner
Nature 449, 726–730
(11 October 2007); doi:10.1038/nature06133
| Summary | Full Text (HTML / PDF) |
perspective
Activity-based protein profiling for the functional annotation of enzymes
Katherine T Barglow & Benjamin F Cravatt
Nature Methods 4, 822–827
(October 2007); doi:10.1038/nmeth1092
| Summary | Full Text (HTML / PDF) |
September
letter
Structural basis of Dscam isoform specificity
Rob Meijers, Roland Puettmann-Holgado, Georgios Skiniotis, Jin-huan Liu, Thomas Walz, Jia-huai Wang & Dietmar Schmucker
Nature 449, 487–491
(27 September 2007); doi:10.1038/nature06147
| Summary | Full Text (HTML / PDF) |
letter
Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1
Gabriele A. Amodeo, Michael J. Rudolph & Liang Tong
Nature 449, 492–495
(27 September 2007); doi:10.1038/nature06127
| Summary | Full Text (HTML / PDF) |
news and views
Chloride finds its place in the transport cycle
Susan G Amara
Nature Structural & Molecular Biology 14, 792–794
(September 2007); doi:10.1038/nsmb0907-792
| Summary | Full Text (HTML / PDF) |
article
Structural insight into filament formation by mammalian septins
Minhajuddin Sirajuddin, Marian Farkasovsky, Florian Hauer, Dorothee Kühlmann, Ian G. Macara, Michael Weyand, Holger Stark & Alfred Wittinghofer
Nature 449, 311–315
(20 September 2007); doi:10.1038/nature06052
| Summary | Full Text (HTML / PDF) |
article
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression
Natalia Mitin, Laurie Betts, Marielle E Yohe, Channing J Der, John Sondek & Kent L Rossman
Nature Structural & Molecular Biology 14, 814–823
(September 2007); doi:10.1038/nsmb1290
| Summary | Full Text (HTML / PDF) |
article
Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'
Dan Feng, Christopher J Bond, Lauren K Ely, Jennifer Maynard & K Christopher Garcia
Nature Immunology 8, 975–983
(2007); doi:10.1038/ni1502
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the IL-15–IL-15Rα complex, a cytokine-receptor unit presented in trans
Mami Chirifu, Chiharu Hayashi, Teruya Nakamura, Sachiko Toma, Tsuyoshi Shuto, Hirofumi Kai, Yuriko Yamagata, Simon J Davis & Shinji Ikemizu
Nature Immunology 8, 1001–1007
(September 2007); doi:10.1038/ni1492
| Summary | Full Text (HTML / PDF) |
article
Structural dynamics in the gating ring of cyclic nucleotide-gated ion channels
Justin W Taraska & William N Zagotta
Nature Structural & Molecular Biology 14, 854–860
(September 2007); doi:10.1038/nsmb1281
| Summary | Full Text (HTML / PDF) |
news and views
When it comes to couple(r)s, do opposites attract?
Sharsti Sandall & Arshad Desai
Nature Structural & Molecular Biology 14, 790–792
(September 2007); doi:10.1038/nsmb0907-790
| Summary | Full Text (HTML / PDF) |
August
letter
Crystal structure of the MgtE Mg2+ transporter
Motoyuki Hattori, Yoshiki Tanaka, Shuya Fukai, Ryuichiro Ishitani & Osamu Nureki
Nature 448, 1072–1075
(30 August 2007); doi:10.1038/nature06093
| Summary | Full Text (HTML / PDF) |
article
Structure-based activity prediction for an enzyme of unknown function
Johannes C. Hermann, Ricardo Marti-Arbona, Alexander A. Fedorov, Elena Fedorov, Steven C. Almo, Brian K. Shoichet & Frank M. Raushel
Nature 448, 775–779
(16 August 2007); doi:10.1038/nature05981
| Summary | Full Text (HTML / PDF) |
news and views
Computational biochemistry: Models of transition
JoAnne Stubbe
Nature 448, 762–763
(16 August 2007); doi:10.1038/448762a
| Full Text (HTML / PDF) |
letter
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
Burckhard Seelig & Jack W. Szostak
Nature 448, 828–831
(16 August 2007); doi:10.1038/nature06032
| Summary | Full Text (HTML / PDF) |
news and views
Biochemistry: Designer enzymes
Michael P. Robertson & William G. Scott
Nature 448, 757–763
(16 August 2007); doi:10.1038/448757a
| Full Text (HTML / PDF) |
article
Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms
Hong-Wei Wang, Vincent H Ramey, Stefan Westermann, Andres E Leschziner, Julie P I Welburn, Yuko Nakajima, David G Drubin, Georjana Barnes & Eva Nogales
Nature Structural & Molecular Biology 14, 721–726
(August 2007); doi:10.1038/nsmb1274
| Summary | Full Text (HTML / PDF) |
brief communications arising
Crystallography: Crystallographic evidence for deviating C3b structure
Bert J. C. Janssen, Randy J. Read, Axel T. Brünger & Piet Gros
Nature 448, E1–E2
(9 August 2007); doi:10.1038/nature06102
| Summary | Full Text (HTML / PDF) |
brief communications arising
Crystallography: Crystallographic evidence for deviating C3b structure (Reply)
A. Abdul Ajees, Krishnasamy Gunasekaran, Sthanam V. L. Narayana & H. M. Krishna Murthy
Nature 448, E2–E3
(9 August 2007); doi:10.1038/nature06103
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat
Charles W Pemble IV, Lynnette C Johnson, Steven J Kridel & W Todd Lowther
Nature Structural & Molecular Biology 14, 704–709
(August 2007); doi:10.1038/nsmb1265
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution
Cosma D Dellisanti, Yun Yao, James C Stroud, Zuo-Zhong Wang & Lin Chen
Nature Neuroscience 10, 953–962
(August 2007); doi:10.1038/nn1942
| Summary | Full Text (HTML / PDF) |
news and views
Nicotinic receptor structure emerging slowly
Titia K Sixma
Nature Neuroscience 10, 937–938
(August 2007); doi:10.1038/nn0807-937
| Summary | Full Text (HTML / PDF) |
article
CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices
Jennifer M R Baker, Rhea P Hudson, Voula Kanelis, Wing-Yiu Choy, Patrick H Thibodeau, Philip J Thomas & Julie D Forman-Kay
Nature Structural & Molecular Biology 14, 738–745
(August 2007); doi:10.1038/nsmb1278
| Summary | Full Text (HTML / PDF) |
July
article
The ubiquitin-specific protease USP28 is required for MYC stability
Nikita Popov, Michael Wanzel, Mandy Madiredjo, Dong Zhang, Roderick Beijersbergen, Rene Bernards, Roland Moll, Stephen J. Elledge & Martin Eilers
Nature Cell Biology 9, 765–774
(July 2007); doi:10.1038/ncb1601
| Summary | Full Text (HTML / PDF) |
news and views
MYC degradation: deubiquitinating enzymes enter the dance
Bruno Amati & Victor J. Sanchez-Arévalo Lobo
Nature Cell Biology 9, 729–731
(July 2007); doi:10.1038/ncb0707-729
| Summary | Full Text (HTML / PDF) |
article
Determination of the sites of tyrosine O-sulfation in peptides and proteins
Yonghao Yu, Adam J Hoffhines, Kevin L Moore & Julie A Leary
Nature Methods 4, 583–588
(July 2007); doi:10.1038/nmeth1056
| Summary | Full Text (HTML / PDF) |
scientific report
The N terminus of the serpin, tengpin, functions to trap the metastable native state
Qingwei Zhang, Ashley M Buckle, Ruby H P Law, Mary C Pearce, Lisa D Cabrita, Gordon J Lloyd, James A Irving, A Ian Smith, Katya Ruzyla, Jamie Rossjohn, Stephen P Bottomley & James C Whisstock
EMBO Reports 8, 658–663
(July 2007); doi:10.1038/sj.embor.7400986
| Summary | Full Text (HTML / PDF) |
June
article
Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40
Yu Chen, Yanhui Xu, Qing Bao, Yongna Xing, Zhu Li, Zheng Lin, Jeffry B Stock, Philip D Jeffrey & Yigong Shi
Nature Structural & Molecular Biology 14, 527–534
(June 2007); doi:10.1038/nsmb1254
| Summary | Full Text (HTML / PDF) |
scientific report
Structural plasticity in the oestrogen receptor ligand-binding domain
Kendall W Nettles, John B Bruning, German Gil, Erin E O'Neill, Jason Nowak, Alun Hughs, Younchang Kim, Eugene R DeSombre, Robert Dilis, Robert N Hanson, Andrzej Joachimiak & Geoffrey L Greene
EMBO Reports 8, 563–568
(June 2007); doi:10.1038/sj.embor.7400963
| Summary | Full Text (HTML / PDF) |
scientific report
Structural insights into a new homodimeric self-activated GTPase family
Stéphanie Gras, Valérie Chaumont, Bernard Fernandez, Philippe Carpentier, Fabienne Charrier-Savournin, Sophie Schmitt, Charles Pineau, Didier Flament, Arnaud Hecker, Patrick Forterre, Jean Armengaud & Dominique Housset
EMBO Reports 8, 569–575
(June 2007); doi:10.1038/sj.embor.7400958
| Summary | Full Text (HTML / PDF) |
letter
Mechanism of coupled folding and binding of an intrinsically disordered protein
Kenji Sugase, H. Jane Dyson & Peter E. Wright
Nature 447, 1021–1025
(21 June 2007); doi:10.1038/nature05858
| Summary | Full Text (HTML / PDF) |
news and views
Biophysics: Proteins hunt and gather
David Eliezer & Arthur G. Palmer, III
Nature 447, 920–921
(21 June 2007); doi:10.1038/447920a
| Summary | Full Text (HTML / PDF) |
news and views
Membrane proteins up for grabs
Gunnar von Heijne
Nature Biotechnology 25, 646–647
(June 2007); doi:10.1038/nbt0607-646
| Summary | Full Text (HTML / PDF) |
article
Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK
Yoshihiro Kobashigawa, Mieko Sakai, Masato Naito, Masashi Yokochi, Hiroyuki Kumeta, Yoshinori Makino, Kenji Ogura, Shinya Tanaka & Fuyuhiko Inagaki
Nature Structural & Molecular Biology 14, 503–510
(June 2007); doi:10.1038/nsmb1241
| Summary | Full Text (HTML / PDF) |
news and views
Moving parts: how the adaptor protein CRK is regulated, and regulates
David Cowburn
Nature Structural & Molecular Biology 14, 465–466
(June 2007); doi:10.1038/nsmb0607-465
| Summary | Full Text (HTML / PDF) |
article
The redox-switch domain of Hsp33 functions as dual stress sensor
Marianne Ilbert, Janina Horst, Sebastian Ahrens, Jeannette Winter, Paul C F Graf, Hauke Lilie & Ursula Jakob
Nature Structural & Molecular Biology 14, 556–563
(June 2007); doi:10.1038/nsmb1244
| Summary | Full Text (HTML / PDF) |
article
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
Thomas Schwarz-Romond, Marc Fiedler, Naoki Shibata, P Jonathan G Butler, Akira Kikuchi, Yoshiki Higuchi & Mariann Bienz
Nature Structural & Molecular Biology 14, 484–492
(June 2007); doi:10.1038/nsmb1247
| Summary | Full Text (HTML / PDF) |
news and views
It takes more than two to tango: Dishevelled polymerization and Wnt signaling
David M Roberts, Kevin C Slep & Mark Peifer
Nature Structural & Molecular Biology 14, 463–465
(June 2007); doi:10.1038/nsmb0607-463
| Summary | Full Text (HTML / PDF) |
brief communication
Microgram-scale protein structure determination by NMR
James M Aramini, Paolo Rossi, Clemens Anklin, Rong Xiao & Gaetano T Montelione
Nature Methods 4, 491–493
(June 2007); doi:10.1038/nmeth1051
| Summary | Full Text (HTML / PDF) |
article
Stabilization of RAD51 nucleoprotein filaments by the C-terminal region of BRCA2
Fumiko Esashi, Vitold E Galkin, Xiong Yu, Edward H Egelman & Stephen C West
Nature Structural & Molecular Biology 14, 468–474
(June 2007); doi:10.1038/nsmb1245
| Summary | Full Text (HTML / PDF) |
article
Interaction with the BRCA2 C terminus protects RAD51–DNA filaments from disassembly by BRC repeats
Owen Richard Davies & Luca Pellegrini
Nature Structural & Molecular Biology 14, 475–483
(June 2007); doi:10.1038/nsmb1251
| Summary | Full Text (HTML / PDF) |
news and views
RAD51, BRCA2 and DNA repair: a partial resolution
Christopher J Lord & Alan Ashworth
Nature Structural & Molecular Biology 14, 461–462
(June 2007); doi:10.1038/nsmb0607-461
| Summary | Full Text (HTML / PDF) |
scientific report
Structural insights into a new homodimeric self-activated GTPase family
Stéphanie Gras, Valérie Chaumont, Bernard Fernandez, Philippe Carpentier, Fabienne Charrier-Savournin, Sophie Schmitt, Charles Pineau, Didier Flament, Arnaud Hecker, Patrick Forterre, Jean Armengaud & Dominique Housset
EMBO Reports 8, 569–575
(June 2007); doi:10.1038/sj.embor.7400958
| Summary | Full Text (HTML / PDF) |
May
article
Atomic structures of amyloid cross-β spines reveal varied steric zippers
Michael R. Sawaya, Shilpa Sambashivan, Rebecca Nelson, Magdalena I. Ivanova, Stuart A. Sievers, Marcin I. Apostol, Michael J. Thompson, Melinda Balbirnie, Jed J. W. Wiltzius, Heather T. McFarlane, Anders Ø. Madsen, Christian Riekel & David Eisenberg
Nature 447, 453–457
(24 May 2007); doi:10.1038/nature05695
| Summary | Full Text (HTML / PDF) |
letter
Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases
G. C. Fox, M. Shafiq, D. C. Briggs, P. P. Knowles, M. Collister, M. J. Didmon, V. Makrantoni, R. J. Dickinson, S. Hanrahan, N. Totty, M. J. R. Stark, S. M. Keyse & N. Q. McDonald
Nature 447, 487–492
(24 May 2007); doi:10.1038/nature05804
| Summary | Full Text (HTML / PDF) |
article
Structural basis of Na+/K+-ATPase adaptation to marine environments
Claudia Colina, Joshua J C Rosenthal, Joseph A DeGiorgis, Deepa Srikumar, Nikhila Iruku & Miguel Holmgren
Nature Structural & Cell Biology 14, 427–431
(May 2007); doi:10.1038/nsmb1237
| Summary | Full Text (HTML / PDF) |
news and views
Budding insights on cell polarity
Dirk Fasshauer & Reinhard Jahn
Nature Structural & Cell Biology 14, 360–362
(May 2007); doi:10.1038/nsmb0507-360
| Summary | Full Text (HTML / PDF) |
article
Structural basis for Rab GTPase activation by VPS9 domain exchange factors
Anna Delprato & David G Lambright
Nature Structural & Molecular Biology 14, 406–412
(May 2007); doi:10.1038/nsmb1232
| Summary | Full Text (HTML / PDF) |
brief communication
Structure-based design of a pathway-specific nuclear import inhibitor
Ahmet E Cansizoglu, Brittany J Lee, Zi Chao Zhang, Beatriz M A Fontoura & Yuh Min Chook
Nature Structural & Molecular Biology 14, 452–454
(May 2007); doi:10.1038/nsmb1229
| Summary | Full Text (HTML / PDF) |
April
article
Sequence-specific dynamics modulate recognition specificity in WW domains
Tao Peng, John S Zintsmaster, Andrew T Namanja & Jeffrey W Peng
Nature Structural & Molecular Biology 14, 325–331
(April 2007); doi:10.1038/nsmb1207
| Summary | Full Text (HTML / PDF) |
article
Structure-guided development of affinity probes for tyrosine kinases using chemical genetics
Jimmy A Blair, Daniel Rauh, Charles Kung, Cai-Hong Yun, Qi-Wen Fan, Haridas Rode, Chao Zhang, Michael J Eck, William A Weiss and Kevan M Shokat
Nature Chemical Biology 3, 229–238
(April 2007); doi:10.1038/nchembio866
| Summary | Full Text (HTML / PDF) |
article
Structural basis for autoinhibition of Notch
Wendy R Gordon, Didem Vardar-Ulu, Gavin Histen, Cheryll Sanchez-Irizarry, Jon C Aster & Stephen C Blacklow
Nature Structural & Molecular Biology 14, 295–300
(April 2007); doi:10.1038/nsmb1227
| Summary | Full Text (HTML / PDF) |
article
Mechanism of auxin perception by the TIR1 ubiquitin ligase
Xu Tan, Luz Irina A. Calderon-Villalobos, Michal Sharon, Changxue Zheng, Carol V. Robinson, Mark Estelle & Ning Zheng
Nature 446, 640–645
(5 April 2007); doi:10.1038/nature05731
| Summary | Full Text (HTML / PDF) |
news and views
Plant biology: Sticking with auxin
Tom Guilfoyle
Nature 446, 621–622
(5 April 2007); doi:10.1038/446621a
| Summary | Full Text (HTML / PDF) |
article
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Lu Deng, Ries J Langley, Patrick H Brown, Gang Xu, Leslie Teng, Qian Wang, Monica I Gonzales, Glenda G Callender, Michael I Nishimura, Suzanne L Topalian & Roy A Mariuzza
Nature Immunology 8, 398–408
(April 2007); doi:10.1038/ni1447
| Summary | Full Text (HTML / PDF) |
March
letter
Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism
Douglas A. Hattendorf, Anna Andreeva, Akanksha Gangar, Patrick J. Brennwald & William I. Weis
Nature 446, 567–571
(29 March 2007); doi:10.1038/nature05635
| Summary | Full Text (HTML / PDF) |
article
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli
Thomas Voets, Grzegorz Owsianik, Annelies Janssens, Karel Talavera and Bernd Nilius
Nature Chemical Biology 3, 174–182
(March 2007); doi:10.1038/nchembio862
| Summary | Full Text (HTML / PDF) |
letter
Relating ligand binding to activation gating in CNGA2 channels
Christoph Biskup, Jana Kusch, Eckhard Schulz, Vasilica Nache, Frank Schwede, Frank Lehmann, Volker Hagen and Klaus Benndorf
Nature 446, 440–443
(22 March 2007); doi:10.1038/nature05596
| Summary | Full Text (HTML / PDF) |
review
Inhibiting transient protein—protein interactions: lessons from the Cdc25 protein tyrosine phosphatases
Johannes Rudolph
Nature Reviews Cancer 7, 202–211
(March 2007); doi:10.1038/nrc2087
| Summary | Full Text (HTML / PDF) |
news and views
How to gate an ion channel: lessons from MthK
Sudha Chakrapani & Eduardo Perozo
Nature Structural & Molecular Biology 14, 180–182
(March 2007); doi:10.1038/nsmb0307-180
| Summary | Full Text (HTML / PDF) |
letter
Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4
Ryo Natsume, Masamitsu Eitoku, Yusuke Akai, Norihiko Sano, Masami Horikoshi and Toshiya Senda
Nature 446, 338–341
(15 March 2007); doi:10.1038/nature05613
| Summary | Full Text (HTML / PDF) |
article
A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule
Fleur E Tynan, Hugh H Reid, Lars Kjer-Nielsen, John J Miles, Matthew C J Wilce, Lyudmila Kostenko, Natalie A Borg, Nicholas A Williamson, Travis Beddoe, Anthony W Purcell, Scott R Burrows, James McCluskey & Jamie Rossjohn
Nature Immunology 8, 268–276
(March 2007); doi:10.1038/ni1432
| Summary | Full Text (HTML / PDF) |
scientific report
Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymeraseη
Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li & Pei Zhou
EMBO reports 8, 247 – 251
(March 2007); doi:10.1038/sj.embor.7400901
| Summary | Full Text (HTML / PDF) |
letter
Structure of an ABC transporter in complex with its binding protein
Kaspar Hollenstein, Dominik C. Frei and Kaspar P. Locher
Nature 446, 213–216
(8 March 2007); doi:10.1038/nature05626
| Summary | Full Text (HTML / PDF) |
brief communication
Structure of a VEGF–VEGF receptor complex determined by electron microscopy
Claudia Ruch, Georgios Skiniotis, Michel O Steinmetz, Thomas Walz & Kurt Ballmer-Hofer
Nature Structural & Molecular Biology 14, 249–250
(March 2007); doi:10.1038/nsmb1202
| Summary | Full Text (HTML / PDF) |
February
review
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
Christian Haass and Dennis J. Selkoe
Nature Reviews Molecular Cell Biology 8, 101–112
(February 2007); doi:10.1038/nrm2101
| Summary | Full Text (HTML / PDF) |
article
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity
Shannon M Doyle, James Shorter, Michal Zolkiewski, Joel R Hoskins, Susan Lindquist & Sue Wickner
Nature Structural & Molecular Biology 14, 114–122
(February 2007); doi:10.1038/nsmb1198
| Summary | Full Text (HTML / PDF) |
article
The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a
Michael L Reese, Srikanth Dakoji, David S Bredt & Volker Dötsch
Nature Structural & Molecular Biology 14, 155–163
(February 2007); doi:10.1038/nsmb1195
| Summary | Full Text (HTML / PDF) |
brief communication
Direct interactions between NEDD8 and ubiquitin E2 conjugating enzymes upregulate cullin-based E3 ligase activity
Eri Sakata, Yoshiki Yamaguchi, Yasuhiro Miyauchi, Kazuhiro Iwai, Tomoki Chiba, Yasushi Saeki, Noriyuki Matsuda, Keiji Tanaka & Koichi Kato
Nature Structural & Molecular Biology 14, 167–168
(February 2007); doi:10.1038/nsmb1191
| Summary | Full Text (HTML / PDF) |
letter
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
Lindsey J. Macpherson, Adrienne E. Dubin, Michael J. Evans, Felix Marr, Peter G. Schultz, Benjamin F. Cravatt and Ardem Patapoutian
Nature 445, 541–545
(1 February 2007); doi:10.1038/nature05544
| First Paragraph | Full Text (HTML / PDF) |
letter
The twisted ion-permeation pathway of a resting voltage-sensing domain
Francesco Tombola, Medha M. Pathak, Pau Gorostiza and Ehud Y. Isacoff
Nature 445, 546–549
(1 February 2007); doi:10.1038/nature05396
| First Paragraph | Full Text (HTML / PDF) |
letter
Structure prediction for the down state of a potassium channel voltage sensor
Michael Grabe, Helen C. Lai, Monika Jain, Yuh Nung Jan and Lily Yeh Jan
Nature 445, 550–553
(1 February 2007); doi:10.1038/nature05494
| First Paragraph | Full Text (HTML / PDF) |
article
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
Tudor A. Fulga, Ilan Elson-Schwab, Vikram Khurana, Michelle L. Steinhilb, Tara L. Spires, Bradley T. Hyman & Mel B. Feany
Nature Cell Biology 9, 139–148
(February 2007); doi:10.1038/ncb1528
| Summary | Full Text (HTML / PDF) |
article
Rapid identification of functionally critical amino acids in a G protein-coupled receptor
Bo Li, Marco Scarselli, Christopher D Knudsen, Soo-Kyung Kim, Kenneth A Jacobson, Sara M McMillin & Jürgen Wess
Nature Methods 4, 169–174
(February 2007); doi:10.1038/nmeth990
| Summary | Full Text (HTML / PDF) |
January
article
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
Olga Boudker, Renae M. Ryan, Dinesh Yernool, Keiko Shimamoto and Eric Gouaux
Nature 445, 387–393
(25 January 2007); doi:10.1038/nature05455
| Summary | Full Text (HTML / PDF) |
article
Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif
Bruce T Seet, Donna M Berry, Jonathan S Maltzman, Jacob Shabason, Monica Raina, Gary A Koretzky, C Jane McGlade and Tony Pawson
The EMBO Journal AOP,
(18 January 2007); doi:10.1038/sj.emboj.7601535
| Summary | Full Text (HTML / PDF) |
article
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme
Uhn Soo Cho and Wenqing Xu
Nature 445, 53–57
(4 January 2007); doi:10.1038/nature05351
| Summary | Full Text (HTML / PDF) |
brief communication
Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization
Sjors H W Scheres, Haixiao Gao, Mikel Valle, Gabor T Herman, Paul P B Eggermont, Joachim Frank & Jose-Maria Carazo
Nature Methods 4, 27–29
(January 2007); doi:10.1038/nmeth992
| Summary | Full Text (HTML / PDF) |
|
