Research library: Structures
2008:
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July
article
The binding sites for cocaine and dopamine in the dopamine transporter overlap
Thijs Beuming et al.
Nature Neuroscience 11, 780789
doi:10.1038/nn.2146
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review
Advances in bacterial promoter recognition and its control by factors that do not bind DNA
Shanil P. Haugen, Wilma Ross & Richard L. Gourse
Nature Reviews Microbiology 6, 507519
(July 2008); doi:10.1038/nrmicro1912
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article
Crystal structure of the ligand-free G-protein-coupled receptor opsin
Jung Hee Park, Patrick Scheerer, Klaus Peter Hofmann, Hui-Woog Choe & Oliver Peter Ernst
Nature 454, 183187
(10 July 2008); doi:10.1038/nature07063
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article
An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells
Erin J Adams, Pavel Strop, Sunny Shin, Yueh-Hsiu Chien & K Christopher Garcia
Nature Immunology 9, 777784
(July 2008); doi:10.1038/ni.1620
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perspective
Insights into signaling from the β2-adrenergic receptor structure
Martin Audet & Michel Bouvier
Nature Chemical Biology 4, 397403
(July 2008); doi:10.1038/nchembio.97
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scientific report
Crucial structural role for the PH and C1 domains of the Vav1 exchange factor
Jonathan Rapley, Victor L J Tybulewicz & Katrin Rittinger
EMBO reports 9, 655661
doi:10.1038/embor.2008.80
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June
letter
Structural basis for EGFR ligand sequestration by Argos
Daryl E. Klein, Steven E. Stayrook, Fumin Shi, Kartik Narayan & Mark A. Lemmon
Nature 453, 12711275
(26 June 2008); doi:10.1038/nature06978
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review
The septin family of GTPases: architecture and dynamics
Christine S. Weirich, Jan P. Erzberger & Yves Barral
Nature Reviews Molecular Cell Biology 9, 478489
(June 2008); doi:10.1038/nrm2407
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article
A structural link between inactivation and block of a K+ channel
Christian Ader et al.
Nature Structural & Molecular Biology 15, 605612
(June 2008); doi:10.1038/nsmb.1430
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article
Internal dynamics control activation and activity of the autoinhibited Vav DH domain
Pilong Li, Ilídio R S Martins, Gaya K Amarasinghe & Michael K Rosen
Nature Structural & Molecular Biology 15, 613618
(June 2008); doi:10.1038/nsmb.1428
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article
Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2
Thomas A Bowden et al.
Nature Structural & Molecular Biology 15, 567572
(June 2008); doi:10.1038/nsmb.1435
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news and views
Evil versus 'eph-ective' use of ephrin-B2
Benhur Lee, Zeynep Akyol Ataman & Lei Jin
Nature Structural & Molecular Biology 15, 540542
(June 2008); doi:10.1038/nsmb0608-540
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letter
An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway
Scott W. Rowlinson et al.
Nature Cell Biology 10, 740747
(June 2008); doi:10.1038/ncb1737
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article
Activity-dependent site-specific changes of glutamate receptor composition in vivo
Andreas Schmid et al.
Nature Neuroscience 11, 659666
(June 2008); doi:10.1038/nn.2122
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article
The central unit within the 19S regulatory particle of the proteasome
Rina Rosenzweig et al.
Nature Structural & Molecular Biology 15, 573580
(June 2008); doi:10.1038/nsmb.14272
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May
article
Proteasome subunit Rpn13 is a novel ubiquitin receptor
Koraljka Husnjak et al.
Nature 453, 481488
(22 May 2008); doi:10.1038/nature06926
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letter
Ubiquitin docking at the proteasome through a novel pleckstrin–homology domain interaction
Patrick Schreiner et al.
Nature 453, 548552
(22 May 2008); doi:10.1038/nature06924
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news and views
Cell Biology: Two hands for degradation
Yasushi Saeki & Keiji Tanaka
Nature 453, 460461
(22 May 2008); doi:10.1038/453460a
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article
Membrane-dependent signal integration by the Ras activator Son of sevenless
Jodi Gureasko et al.
Nature Structural & Molecular Biology 14, 452461
(May 2008); doi:10.1038/nsmb.1418
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article
Crystal structure of squid rhodopsin
Midori Murakami & Tsutomu Kouyama
Nature 453, 363367
(15 May 2008); doi:10.1038/nature06925
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news and views
Signal Transduction: The rhodopsin story continued
Gebhard F. X. Schertler
Nature 453, 292293
(15 May 2008); doi:10.1038/453292a
| Full Text (HTML / PDF) |
April
article
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Cai-Guang Yang et al.
Nature 452, 961965
(24 April 2008); doi:10.1038/nature06889
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article
Reciprocal regulation of the Ca2+ and H+ sensitivity in the SLO1 BK channel conferred by the RCK1 domain
Shangwei Hou, Rong Xu, Stefan H Heinemann & Toshinori Hoshi
Nature Structural & Molecular Biology 15, 403410
(April 2008); doi:10.1038/nsmb.1398
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brief communication
Crystal structures of two human vitronectin, urokinase and urokinase receptor complexes
Qing Huai et al.
Nature Structural & Molecular Biology 15, 422423
(April 2008); doi:10.1038/nsmb.1404
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article
Isolation of an active step I spliceosome and composition of its RNP core
Sergey Bessonov, Maria Anokhina, Cindy L. Will, Henning Urlaub & Reinhard Lührmann
Nature 452, 846850
(17 April 2008); doi:10.1038/nature06842
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article
The retinitis pigmentosa 2 gene product is a GTPase-activating protein for Arf-like 3
Stefan Veltel, Raphael Gasper, Elke Eisenacher & Alfred Wittinghofer
Nature Structural & Molecular Biology 15, 373380
(April 2008); doi:10.1038/nsmb.1396
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article
NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Kendall W Nettles et al.
Nature Chemical Biology 4, 241247
(April 2008); doi:10.1038/nchembio.76
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news and views
Fast-tracking steroid receptor crystallization
Sylvie Mader
Nature Chemical Biology 4, 226227
(April 2008); doi:10.1038/nchembio0408-226
| Full Text (HTML / PDF) |
article
A nuclear receptor-like pathway regulating multidrug resistance in fungi
Jitendra K. Thakur et al.
Nature 452, 604609
(3 April 2008); doi:10.1038/nature06836
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news and views
Drug resistance: The fight against fungi
André Goffeau
Nature 452, 541542
(3 April 2008); doi:10.1038/452541a
| Full Text (HTML / PDF) |
article
Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer
Gisela D Cymes & Claudio Grosman
Nature Structural & Molecular Biology 15, 389396
(April 2008); doi:10.1038/nsmb.1407
| Summary | Full Text (HTML / PDF) |
March
letter
X-ray structure of a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf & Raimund Dutzler
Nature 452, 375379
(20 March 2008); doi:10.1038/nature06717
| Summary | Full Text (HTML / PDF) |
article
Pyruvate kinase M2 is a phosphotyrosine-binding protein
Heather R. Christofk, Matthew G. Vander Heiden, Ning Wu, John M. Asara & Lewis C. Cantley
Nature 452, 181186
(13 March 2008); doi:10.1038/nature06667
| Summary | Full Text (HTML / PDF) |
letter
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
Nature 452, 230233
(13 March 2008); doi:10.1038/nature06734
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article
A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
Héctor Salazar et al.
Nature Neuroscience 11, 255261
(March 2008); doi:10.1038/nn2056
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February
review
Cellular cholesterol trafficking and compartmentalization
Elina Ikonen
Nature Reviews Molecular Cell Biology 9, 125138
(February 2008); doi:10.1038/nrm2336
| Summary | Full Text (HTML / PDF) |
letter
The structural basis of protein acetylation by the p300/CBP transcriptional coactivator
Xin Liu et al.
Nature 451, 846850
(14 February 2008); doi:10.1038/nature06546
| Summary | Full Text (HTML / PDF) |
review
Membrane lipids: where they are and how they behave
Gerrit van Meer, Dennis R. Voelker & Gerald W. Feigenson
Nature Reviews Molecular Cell Biology 9, 112124
(February 2008); doi:10.1038/nrm2330
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article
Crystal structure of the multifunctional Gβ5–RGS9 complex
Matthew L Cheever, Jason T Snyder, Svetlana Gershburg, David P Siderovski, T Kendall Harden & John Sondek
Nature Structural & Molecular Biology 15, 155162
(February 2008); doi:10.1038/nsmb.1377
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review
Membrane recognition by phospholipid-binding domains
Mark A. Lemmon
Nature Reviews Molecular Cell Biology 9, 99111
(February 2008); doi:10.1038/nrm2328
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January
review
Molecular architecture of the kinetochore–microtubule interface
Iain M. Cheeseman & Arshad Desai
Nature Reviews Molecular Cell Biology 9, 3346
(January 2008); doi:10.1038/nrm2310
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article
Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions
Xiaoyan Chen, Heli Liu, Ann H R Shim, Pamela J Focia & Xiaolin He
Nature Structural & Molecular Biology 15, 5056
(January 2008); doi:10.1038/nsmb1350
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review
Heterotrimeric G protein activation by G-protein-coupled receptors
William M. Oldham & Heidi E. Hamm
Nature Reviews Molecular Cell Biology 9, 6071
(January 2008); doi:10.1038/nrm2299
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article
Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase
Jianbo Diao, Ying Zhang, Jon M Huibregtse, Daoguo Zhou & Jue Chen
Nature Structural & Molecular Biology 15, 6570
(January 2008); doi:10.1038/nsmb1346
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brief communication
Structural basis for activation of the autoinhibitory C-terminal kinase domain of p90 RSK2
Margarita Malakhova et al.
Nature Structural & Molecular Biology 15, 112113
(January 2008); doi:10.1038/nsmb1347
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