article Genome sequence, comparative analysis and haplotype structure of the domestic dog
Kerstin Lindblad-Toh, Claire M Wade, Tarjei S. Mikkelsen, Elinor K. Karlsson, David B. Jaffe, Michael Kamal, Michele Clamp, Jean L. Chang, Edward J. Kulbokas, III, Michael C. Zody, Evan Mauceli, Xiaohui Xie, Matthew Breen, Robert K. Wayne, Elaine A. Ostrander, Chris P. Ponting, Francis Galibert, Douglas R. Smith, Pieter J. deJong, Ewen Kirkness, Pablo Alvarez, Tara Biagi, William Brockman, Jonathan Butler, Chee-Wye Chin, April Cook, James Cuff, Mark J. Daly, David DeCaprio, Sante Gnerre, Manfred Grabherr, Manolis Kellis, Michael Kleber, Carolyne Bardeleben, Leo Goodstadt, Andreas Heger, Christophe Hitte, Lisa Kim, Klaus-Peter Koepfli, Heidi G. Parker, John P. Pollinger, Stephen M. J. Searle, Nathan B. Sutter, Rachael Thomas and Caleb Webber, Broad Sequencing Platform members and Eric S. Lander Nature438, 803–819
(08 December 2005); doi:10.1038/nature04338
| Summary | Full Text (HTML / PDF) |
news and views Genomics: The dog has its day
Hans Ellegren Nature438, 745–746
(08 December 2005); doi:10.1038/438745a
| Full Text (HTML / PDF) |
article High-throughput screening of effective siRNAs from RNAi libraries delivered via bacterial invasion
Hui-Fen Zhao, Denis L'Abbé, Normand Jolicoeur, Meiqun Wu, Zhen Li, Zhenbao Yu and Shi-Hsiang Shen Nature Methods2, 967–973
(December 2005); doi:10.1038/nmeth812
| Abstract | Full Text (HTML/PDF) |
letter Global analysis of protein phosphorylation in yeast
Jason Ptacek, Geeta Devgan, Gregory Michaud, Heng Zhu, Xiaowei Zhu, Joseph Fasolo, Hong Guo, Ghil Jona, Ashton Breitkreutz, Richelle Sopko, Rhonda R. McCartney, Martin C. Schmidt, Najma Rachidi, Soo-Jung Lee, Angie S. Mah, Lihao Meng, Michael J. R. Stark, David F. Stern, Claudio De Virgilio, Mike Tyers, Brenda Andrews, Mark Gerstein, Barry Schweitzer, Paul F. Predki and Michael Snyder Nature438, 679–684
(01 December 2005); doi:10.1038/nature04187
| First Paragraph | Full Text (HTML / PDF) |
brief communication Positional proteomics: selective recovery and analysis of N-terminal proteolytic peptides
Lucy McDonald, Duncan H L Robertson, Jane L Hurst and Robert J Beynon Nature Methods2, 955–957
(December 2005); doi:10.1038/nmeth811
| First Paragraph | Full Text (HTML/PDF) |
November
review article Genotyping errors: causes, consequences and solutions
François Pompanon, Aurélie Bonin, Eva Bellemain and Pierre Taberlet Nature Reviews Genetics6, 847–846
(November 2005); doi:10.1038/nrg1707
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article Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling
Atsushi Kuno, Noboru Uchiyama, Shiori Koseki-Kuno, Youji Ebe, Seigo Takashima, Masao Yamada and Jun Hirabayashi Nature Methods2, 851–856
(November 2005); doi:10.1038/nmeth803
| Abstract | Full Text (HTML/PDF) |
letter A quantitative protein interaction network for the ErbB receptors using protein microarrays
Richard B. Jones, Andrew Gordus, Jordan A. Krall and Gavin MacBeath NatureAdvance online publication
(6 November 2005); doi:10.1038/nature04177
| Abstract | Full Text (HTML / PDF) |
letter A protein interaction network of the malaria parasite Plasmodium falciparum
Douglas J. LaCount , Marissa Vignali, Rakesh Chettier, Amit Phansalkar, Russell Bell, Jay R. Hesselberth, Lori W. Schoenfeld, Irene Ota, Sudhir Sahasrabudhe, Cornelia Kurschner, Stanley Fields and Robert E. Hughes Nature438, 103–107
(03 November 2005); doi:10.1038/nature04104
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article Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits
Margarete Mehrabian, Hooman Allayee, Jirina Stockton, Pek Yee Lum, Thomas A Drake, Lawrence W Castellani, Michael Suh, Christopher Armour, Stephen Edwards, John Lamb, Aldons J Lusis and Eric E Schadt Nature Genetics37, 1224–1233
(November 2005); doi:10.1038/ng1619
| Abstract
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technical report Second-generation shRNA libraries covering the mouse and human genome
Jose M Silva, Mamie Z Li, Ken Chang, Wei Ge, Michael C Golding, Richard J Rickles, Despina Siolas, Guang Hu, Patrick J Paddison, Michael R Schlabach, Nihar Sheth, Jeff Bradshaw, Julia Burchard, Amit Kulkarni, Guy Cavet, Ravi Sachidanandam, W Richard McCombie, Michele A Cleary, Stephen J Elledge and Gregory J Hannon Nature Genetics37, 1281–1288
(November 2005); doi:10.1038/ng1650
| Abstract
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October
article A haplotype map of the human genome
The International HapMap Consortium Nature437, 1299–1320
(27 October 2005); doi:10.1038/nature04226
| Summary | Full Text (HTML / PDF) |
letter A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
Matthew R Lincoln, Alexandre Montpetit, M Zameel Cader, Janna Saarela, David A Dyment, Milvi Tiislar, Vincent Ferretti, Pentti J Tienari, A Dessa Sadovnick, Leena Peltonen, George C Ebers and Thomas J Hudson Nature Genetics37, 1108–1112
(October 2005); doi:10.1038/ng1647
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letter A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility
David Reich, Nick Patterson, Philip L De Jager, Gavin J McDonald, Alicja Waliszewska, Arti Tandon, Robin R Lincoln, Cari DeLoa, Scott A Fruhan, Philippe Cabre, Odile Bera, Gilbert Semana, M Ann Kelly, David A Francis, Kristin Ardlie, Omar Khan, Bruce A C Cree, Stephen L Hauser, Jorge R Oksenberg and David A Hafler Nature Genetics37, 1113–1118
(October 2005); doi:10.1038/ng1646
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letter Towards a proteome-scale map of the human protein-protein interaction network
Jean-François Rual, Kavitha Venkatesan, Tong Hao, Tomoko Hirozane-Kishikawa, Amélie Dricot, Ning Li, Gabriel F. Berriz, Francis D. Gibbons, Matija Dreze, Nono Ayivi-Guedehoussou, Niels Klitgord, Christophe Simon, Mike Boxem, Stuart Milstein, Jennifer Rosenberg, Debra S. Goldberg, Lan V. Zhang, Sharyl L. Wong, Giovanni Franklin, Siming Li, Joanna S. Albala, Janghoo Lim, Carlene Fraughton, Estelle Llamosas, Sebiha Cevik, Camille Bex, Philippe Lamesch, Robert S. Sikorski, Jean Vandenhaute, Huda Y. Zoghbi, Alex Smolyar, Stephanie Bosak, Reynaldo Sequerra, Lynn Doucette-Stamm, Michael E. Cusick, David E. Hill, Frederick P. Roth and Marc Vidal Nature437, 1173–1178
(20 October 2005); doi:10.1038/nature04209
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review article The new cytogenetics: blurring the boundaries with molecular biology
Michael R. Speicher and Nigel P. Carter Nature Reviews Genetics6, 782–792
(October 2005); doi:10.1038/nrg1692
| Abstract | Full Text (HTML / PDF) |
letter A network-based analysis of systemic inflammation in humans
Steve E. Calvano, Wenzhong Xiao, Daniel R. Richards, Ramon M. Felciano, Henry V. Baker, Raymond J. Cho, Richard O. Chen, Bernard H. Brownstein, J. Perren Cobb, S. Kevin Tschoeke, Carol Miller-Graziano, Lyle L. Moldawer, Michael N. Mindrinos, Ronald W. Davis, Ronald G. Tompkins, Stephen F. Lowry and Inflamm and Host Response to Injury Large Scale Collab. Res. Program Nature437, 1032–1037
(13 October 2005); doi:10.1038/nature03985
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September
article Regulated cell-to-cell variation in a cell-fate decision system
Alejandro Colman-Lerner, Andrew Gordon, Eduard Serra, Tina Chin, Orna Resnekov, Drew Endy, C. Gustavo Pesce and Roger Brent Nature437, 699–706
(29 September 2005); doi:10.1038/nature03998
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article A streamlined platform for high-content functional proteomics of primary human specimens
Nadim Jessani, Sherry Niessen, BinQing Q Wei, Monica Nicolau, Mark Humphrey, Youngran Ji, Wonshik Han, Dong-Young Noh, John R Yates, III Stefanie S Jeffrey and Benjamin F Cravatt Nature Methods2, 691–697
(September 2005); doi:10.1038/nmeth778
| Abstract | Full Text (HTML/PDF) |
review article Proteomics of organelles and large cellular structures
John R. Yates III, Annalyn Gilchrist, Kathryn E. Howell and John J. M. Bergeron Nature Reviews Molecular Cell Biology6, 702–714
(September 2005); doi:10.1038/nrm1711
| Abstract | Full Text (HTML / PDF) |
letter Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs
Brendan J Frey, Naveed Mohammad, Quaid D Morris, Wen Zhang, Mark D Robinson, Sanie Mnaimneh, Richard Chang, Qun Pan, Eric Sat, Janet Rossant, Benoit G Bruneau, Jane E Aubin, Benjamin J Blencowe and Timothy R Hughes Nature Genetics37, 991–996
(September 2005); doi:10.1038/ng1630
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news and views Toward a universal multistrain bacterial vaccine
Robert G Feldman Nature Biotechnology23, 1087–1088
(September 2005); doi:10.1038/nbt0905-1087
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brief communication Gene expression profiling in single cells within tissue
Paola Capodieci, Michael Donovan, Heidi Buchinsky, Yusuf Jeffers, Carlos Cordon-Cardo, William Gerald, Jon Edelson, Shailesh M Shenoy and Robert H Singer Nature Methods2, 663–665
(September 2005); doi:10.1038/nmeth786
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August
article Initial sequence of the chimpanzee genome and comparison with the human genome
The Chimpanzee Sequencing and Analysis Consortium Nature437, 69–87
(01 September 2005); doi:10.1038/nature04072
| Abstract | Full Text (HTML / PDF) |
article A genome-wide comparison of recent chimpanzee and human segmental duplications
Ze Cheng, Mario Ventura, Xinwei She, Philipp Khaitovich, Tina Graves, Kazutoyo Osoegawa, Deanna Church, Pieter DeJong, Richard K. Wilson, Svante Pääbo, Mariano Rocchi and Evan E. Eichler Nature437, 88–93
(01 September 2005); doi:10.1038/nature04000
| Abstract | Full Text (HTML / PDF) |
analysis Probabilistic model of the human protein-protein interaction network
Daniel R Rhodes, Scott A Tomlins, Sooryanarayana Varambally, Vasudeva Mahavisno, Terrence Barrette, Shanker Kalyana-Sundaram, Debashis Ghosh, Akhilesh Pandey and Arul M Chinnaiyan Nature Biotechnology23, 951–959
(August 2005); doi:10.1038/nbt1103
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research article High-throughput generation of small antibacterial peptides with improved activity
Kai Hilpert, Rudolf Volkmer-Engert, Tess Walter and Robert E W Hancock Nature Biotechnology23, 1008–1012
(August 2005); doi:10.1038/nbt1113
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article Nova regulates brain-specific splicing to shape the synapse
Jernej Ule, Alja Ule, Joanna Spencer, Alan Williams, Jing-Shan Hu, Melissa Cline, Hui Wang, Tyson Clark, Claire Fraser, Matteo Ruggiu, Barry R Zeeberg, David Kane, John N Weinstein, John Blume and Robert B Darnell Nature Genetics37, 844–852
(August 2005); doi:10.1038/ng1610
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news and views Splicing on the brain
Benjamin J Blencowe Nature Genetics37, 796–797
(August 2005); doi:10.1038/ng0805-796
| Full Text (HTML/PDF) |
letter Identification of JAK/STAT signalling components by genome-wide RNA interference
Patrick Müller, David Kuttenkeuler, Viola Gesellchen, Martin P. Zeidler and Michael Boutros Nature436, 871–875
(11 August 2005); doi:10.1038/nature03869
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letter A high-resolution map of active promoters in the human genome
Tae Hoon Kim, Leah O. Barrera, Ming Zheng, Chunxu Qu, Michael A. Singer, Todd A. Richmond, Yingnian Wu, Roland D. Green and Bing Ren Nature436, 876–880
(11 August 2005); doi:10.1038/nature03877
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article Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
Michael Weber, Jonathan J Davies, David Wittig, Edward J Oakeley, Michael Haase, Wan L Lam and Dirk Schübeler Nature Genetics37, 853–862
(August 2005); doi:10.1038/ng1598
| Abstract | Full Text (HTML/PDF) |
July
article Systematic analysis of genes required for synapse structure and function
Derek Sieburth, QueeLim Ch'ng, Michael Dybbs, Masoud Tavazoie, Scott Kennedy, Duo Wang, Denis Dupuy, Jean-François Rual, David E. Hill, Marc Vidal, Gary Ruvkun and Joshua M. Kaplan Nature436, 510–517
(28 July 2005); doi:10.1038/nature03809
| Abstract | Full Text (HTML / PDF) |
article Genes that mediate breast cancer metastasis to lung
Andy J. Minn , Gaorav P. Gupta, Peter M. Siegel, Paula D. Bos, Weiping Shu, Dilip D. Giri, Agnes Viale, Adam B. Olshen, William L. Gerald and Joan Massagué Nature436, 518–524
(28 July 2005); doi:10.1038/nature03799
| Abstract | Full Text (HTML / PDF) |
news and views Neuroscience: Genomics reaches the synapse
Cori Bargmann Nature436, 473–474
(28 July 2005); doi:10.1038/436473a
| Full Text (HTML / PDF) |
June
letter MicroRNA expression profiles classify human cancers
Jun Lu , Gad Getz, Eric A. Miska , Ezequiel Alvarez-Saavedra, Justin Lamb, David Peck, Alejandro Sweet-Cordero, Benjamin L. Ebert, Raymond H. Mak, Adolfo A. Ferrando, James R. Downing, Tyler Jacks, H. Robert Horvitz and Todd R. Golub Nature435, 834–838
(09 June 2005); doi:10.1038/nature03702
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news and views Cancer genomics: Small RNAs with big impacts
Paul S. Meltzer Nature435, 745–746
(09 June 2005); doi:10.1038/435745a
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article Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
Yu-Hua Tseng, Atul J. Butte, Efi Kokkotou, Vijay K. Yechoor, Cullen M. Taniguchi, Kristina M. Kriauciunas, Aaron M. Cypess, Michio Niinobe, Kazuaki Yoshikawa, Mary Elizabeth Patti and C. Ronald Kahn Nature Cell Biology7, 601–611
(June 2005); doi:10.1038/ncb1259
| Abstract | Full Text (HTML/PDF) |
news and views Fickle factor foils fat fate
Ormond A. MacDougald and Charles F. Burant Nature Cell Biology7, 543–545
(June 2005); doi:10.1038/ncb0605-543
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research article A high-throughput assay for assessing the cell permeability of combinatorial libraries
Peng Yu, Bo Liu and Thomas Kodadek Nature Biotechnology23, 746–751
(June 2005); doi:10.1038/nbt1099
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article Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
Jeffrey P. MacKeigan, Leon O. Murphy and John Blenis Nature Cell Biology7, 591–600
(June 2005); doi:10.1038/ncb1258
| Abstract | Full Text (HTML/PDF) |
brief communication A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
Philip Stephens, Sarah Edkins, Helen Davies, Chris Greenman, Charles Cox, Chris Hunter, Graham Bignell, Jon Teague, Raffaella Smith, Claire Stevens, Sarah O'Meara, Adrian Parker, Patrick Tarpey, Tim Avis, Andy Barthorpe, Lisa Brackenbury, Gemma Buck, Adam Butler, Jody Clements, Jennifer Cole, Ed Dicks, Ken Edwards, Simon Forbes, Matthew Gorton, Kristian Gray, Kelly Halliday, Rachel Harrison, Katy Hills, Jonathon Hinton, David Jones, Vivienne Kosmidou, Ross Laman, Richard Lugg, Andrew Menzies, Janet Perry, Robert Petty, Keiran Raine, Rebecca Shepherd, Alexandra Small, Helen Solomon, Yvonne Stephens, Calli Tofts, Jennifer Varian, Anthony Webb, Sofie West, Sara Widaa, Andrew Yates, Francis Brasseur, Colin S Cooper, Adrienne M Flanagan, Anthony Green, Maggie Knowles, Suet Y Leung, Leendert H J Looijenga, Bruce Malkowicz, Marco A Pierotti, Bin Teh, Siu T Yuen, Andrew G Nicholson, Sunil Lakhani, Douglas F Easton, Barbara L Weber, Michael R Stratton, P Andrew Futreal and Richard Wooster Nature Genetics37, 590–592
(June 2005); doi:10.1038/ng1571
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analysis Mining for regulatory programs in the cancer transcriptome
Daniel R Rhodes, Shanker Kalyana-Sundaram, Vasudeva Mahavisno, Terrence R Barrette, Debashis Ghosh and Arul M Chinnaiyan Nature Genetics37, 579–583
(June 2005); doi:10.1038/ng1578
| Abstract | Full Text (HTML/PDF) |
review article Miniaturization in functional genomics and proteomics
Sascha Sauer, Bodo M. H. Lange, Johan Gobom, Lajos Nyarsik, Harald Seitz and Hans Lehrach Nature Reviews Genetics6, 465–476
(June 2005); doi:10.1038/nrg1618
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article Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells
Sven Eyckerman, Irma Lemmens, Dominiek Catteeuw, Annick Verhee, Joel Vandekerckhove, Sam Lievens and Jan Tavernier Nature Methods2, 427–433
(June 2005); doi:10.1038/nmeth760
| Abstract | Full Text (HTML/PDF) |
news and views Perturbing interactions
Stuart Milstein and Marc Vidal Nature Methods2, 412–414
(June 2005); doi:10.1038/nmeth0605-412
| Abstract | Full Text (HTML/PDF) |
May
research article Enzyme family-specific and activity-based screening of chemical libraries using enzyme microarrays
Daniel P Funeriu, Jörg Eppinger, Lucile Denizot, Masato Miyake and Jun Miyake Nature Biotechnology23, 622–627
(May 2005); doi:10.1038/nbt1090
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letter Combinatorial microRNA target predictions
Azra Krek, Dominic Grün, Matthew N Poy, Rachel Wolf, Lauren Rosenberg, Eric J Epstein, Philip MacMenamin, Isabelle da Piedade, Kristin C Gunsalus, Markus Stoffel and Nikolaus Rajewsky Nature Genetics37, 495–500
(May 2005); doi:10.1038/ng1536
| First Paragraph | Full Text (HTML/PDF) |
research article Gene knockdown by large circular antisense for high-throughput functional genomics
Yun-Han Lee, Ik-Jae Moon, Bin Hur, Jeong-Hoh Park, Kil-Hwan Han, Seok-Yong Uhm, Yong-Joo Kim, Koo-Jeong Kang, Jong-Wook Park, Young-Bae Seu, Young-Ho Kim and Jong-Gu Park Nature Biotechnology23, 591–599
(May 2005); doi:10.1038/nbt1089
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article Epistasis analysis with global transcriptional phenotypes
Nancy Van Driessche, Janez Demsar, Ezgi O Booth, Paul Hill, Peter Juvan, Blaz Zupan, Adam Kuspa and Gad Shaulsky Nature Genetics37, 471–477
(May 2005); doi:10.1038/ng1545
| Abstract | Full Text (HTML/PDF) |
news and views Universal epistasis analysis
Timothy R Hughes Nature Genetics37, 457–458
(May 2005); doi:10.1038/ng0505-457
| Full Text (HTML/PDF) |
analysis Systematic interpretation of genetic interactions using protein networks
Ryan Kelley and Trey Ideker Nature Biotechnology23, 561–566
(May 2005); doi:10.1038/nbt1096
| Abstract | Full Text (HTML/PDF) |
article The genome of the social amoeba Dictyostelium discoideum
L.Eichinger, J. A. Pachebat, G. Glöckner, M.-A. Rajandream, R. Sucgang , M. Berriman , J. Song , R. Olsen , K. Szafranski , Q. Xu , B. Tunggal , S. Kummerfeld , M. Madera , B. A. Konfortov , F. Rivero , A. T. Bankier , R. Lehmann , N. Hamlin , R. Davies , P. Gaudet , P. Fey , K. Pilcher , G. Chen , D. Saunders , E. Sodergren , P. Davis , A. Kerhornou , X. Nie , N. Hall , C. Anjard , L. Hemphill , N. Bason , P. Farbrother , B. Desany , E. Just , T. Morio , R. Rost , C. Churcher , J. Cooper , S. Haydock , N. van Driessche , A. Cronin , I. Goodhead , D. Muzny , T. Mourier , A. Pain , M. Lu , D. Harper , R. Lindsay , H. Hauser , K. James , M. Quiles , M. Madan Babu , T. Saito , C. Buchrieser , A. Wardroper , M. Felder , M. Thangavelu , D. Johnson , A. Knights , H. Loulseged , K. Mungall , K. Oliver , C. Price , M. A. Quail , H. Urushihara , J. Hernandez , E. Rabbinowitsch , D. Steffen , M. Sanders , J. Ma , Y. Kohara , S. Sharp , M. Simmonds , S. Spiegler , A. Tivey , S. Sugano , B. White , D. Walker , J. Woodward , T. Winckler , Y. Tanaka , G. Shaulsky , M. Schleicher , G. Weinstock , A. Rosenthal , E. C. Cox , R. L. Chisholm , R. Gibbs , W. F. Loomis , M. Platzer , R. R. Kay , J. Williams , P. H. Dear , A. A. Noegel , B. Barrell and A. Kuspa Nature435, 43–57
(05 May 2005); doi:10.1038/nature03481
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article Independence and reproducibility across microarray platforms
Jennie E Larkin, Bryan C Frank, Haralambos Gavras, Razvan Sultana and John Quackenbush
Nature Methods2, 337–344
(May 2005); doi:10.1038/nmeth757
| Abstract | Full Text (HTML/PDF) |
article Multiple-laboratory comparison of microarray platforms
Rafael A Irizarry, Daniel Warren, Forrest Spencer, Irene F Kim, Shyam Biswal, Bryan C Frank, Edward Gabrielson, Joe G N Garcia, Joel Geoghegan, Gregory Germino, Constance Griffin, Sara C Hilmer, Eric Hoffman, Anne E Jedlicka, Ernest Kawasaki, Francisco Martínez-Murillo, Laura Morsberger, Hannah Lee, David Petersen, John Quackenbush, Alan Scott, Michael Wilson, Yanqin Yang, Shui Qing Ye and Wayne Yu
Nature Methods2, 345–350
(May 2005); doi:10.1038/nmeth756
| Abstract | Full Text (HTML/PDF) |
article Standardizing global gene expression analysis between laboratories and across platforms
Members of the Toxicogenomics Research Consortium: B.K. Weis Nature Methods2, 351–356
(May 2005); doi:10.1038/nmeth754
| Abstract | Full Text (HTML/PDF) |
news and views Of fish and chips
Gavin Sherlock Nature Methods2, 329–330
(May 2005); doi:10.1038/nmeth0505-329
| Abstract | Full Text (HTML/PDF) |
April
research article Enrichment and analysis of peptide subsets using fluorous affinity tags and mass spectrometry
Scott M Brittain, Scott B Ficarro, Ansgar Brock and Eric C Peters Nature Biotechnology23, 463–468
(April 2005); doi:10.1038/nbt1076
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review article Model organisms: Chemistry-to-gene screens in Caenorhabditis elegans
Andrew K. Jones, Steven D. Buckingham and David B. Sattelle Nature Reviews Drug Discovery4, 321–330
(April 2005); doi:10.1038/nrd1692
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article In vivo protein biotinylation for identification of organ-specific antigens accessible from the vasculature
Jascha-N Rybak, Anna Ettorre, Brigitte Kaissling, Raffaella Giavazzi, Dario Neri and Giuliano Elia Nature Methods2, 291–298
(April 2005); doi:10.1038/nmeth745
| Abstract | Full Text (HTML/PDF) |
article Reverse engineering of regulatory networks in human B cells
Katia Basso, Adam A Margolin, Gustavo Stolovitzky, Ulf Klein, Riccardo Dalla-Favera and Andrea Califano Nature Genetics37, 382–390
(April 2005); doi:10.1038/ng1532
| Abstract | Full Text (HTML/PDF) |
article Identification of microRNAs of the herpesvirus family
Sébastien Pfeffer, Alain Sewer, Mariana Lagos-Quintana, Robert Sheridan, Chris Sander, Friedrich A Grässer, Linda F van Dyk, C Kiong Ho, Stewart Shuman, Minchen Chien, James J Russo, Jingyue Ju, Glenn Randall, Brett D Lindenbach, Charles M Rice, Viviana Simon, David D Ho, Mihaela Zavolan and Thomas Tuschl Nature Methods2, 269–276
(April 2005); doi:10.1038/nmeth746
| Abstract | Full Text (HTML/PDF) |
news and views Herpesviruses throw a curve ball: new insights into microRNA biogenesis and evolution
Joel R Neilson & Phillip A Sharp Nature Methods2, 252–254
(April 2005); doi:10.1038/nmeth0405-252
| Abstract | Full Text (HTML/PDF) |
review article Insights into host responses against pathogens from transcriptional profiling
Richard G. Jenner and Richard A. Young Nature Reviews Microbiology3, 281–294
(April 2005); doi:10.1038/nrmicro1126
| Summary | Full Text (HTML / PDF) |
March
research article Programmable ligand-controlled riboregulators of eukaryotic gene expression
Travis S Bayer and Christina D Smolke Nature Biotechnology23, 337–343
(March 2005); doi:10.1038/nbt1069
| First Paragraph | Full Text (HTML/PDF) |
news and views Plug-and-play with RNA
Farren J Isaacs and James J Collins Nature Biotechnology23, 306–307
(March 2005); doi:10.1038/nbt0305-306
| Full Text (HTML/PDF) |
article Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
Leonid Bystrykh, Ellen Weersing, Bert Dontje, Sue Sutton, Mathew T Pletcher, Tim Wiltshire, Andrew I Su, Edo Vellenga, Jintao Wang, Kenneth F Manly, Lu Lu, Elissa J Chesler, Rudi Alberts, Ritsert C Jansen, Robert W Williams, Michael P Cooke and Gerald de Haan Nature Genetics37, 225–232
(March 2005); doi:10.1038/ng1497
| Abstract | Full Text (HTML/PDF) |
news and views Mapping expression in randomized rodent genomes
Karl W Broman Nature Genetics37, 209–210
(March 2005); doi:10.1038/ng0305-209
| Full Text (HTML/PDF) |
technical report MAGIC, an in vivo genetic method for the rapid construction of recombinant DNA molecules
Mamie Z Li and Stephen J Elledge Nature Genetics37, 311–319
(March 2005); doi:10.1038/ng1505
| Abstract | Full Text (HTML/PDF) |
February
letter An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas
Paul Roepman, Lodewyk F A Wessels, Nienke Kettelarij, Patrick Kemmeren, Antony J Miles, Philip Lijnzaad, Marcel G J Tilanus, Ronald Koole, Gert-Jan Hordijk, Peter C van der Vliet, Marcel J T Reinders, Piet J Slootweg and Frank C P Holstege Nature Genetics37, 182–186
(February 2005); doi:10.1038/ng1502
| First Paragraph | Full Text (HTML/PDF) |
letters to nature Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
Lee P. Lim, Nelson C. Lau, Philip Garrett-Engele, Andrew Grimson, Janell M. Schelter, John Castle, David P. Bartel, Peter S. Linsley and Jason M. Johnson Nature433, 769–773
(17 February 2005); doi:10.1038/nature03315
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review article Reconstruction of cellular signalling networks and analysis of their properties
Jason A. Papin , Tony Hunter, Bernhard O. Palsson and Shankar Subramaniam Nature Reviews Molecular Cell Biology6, 99–111
(2005); doi:10.1038/nrm1570
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article An extracellular matrix microarray for probing cellular differentiation
Christopher J Flaim, Shu Chien and Sangeeta N Bhatia Nature Methods2, 119–125
(February 2005); doi:10.1038/nmeth736
| Abstract | Full Text (HTML/PDF) |
review article DNA supercoiling — a global transcriptional regulator for enterobacterial growth?
Andrew Travers and Georgi Muskhelishvili Nature Reviews Microbiology3, 157–169
(February 2005); doi:10.1038/nrmicro1088
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research article Functional annotation and network reconstruction through cross-platform integration of microarray data
Xianghong Jasmine Zhou, Ming-Chih J Kao, Haiyan Huang, Angela Wong, Juan Nunez-Iglesias, Michael Primig, Oscar M Aparicio, Caleb E Finch, Todd E Morgan and Wing Hung Wong Nature Biotechnology23, 238–243
(February 2005); doi:10.1038/nbt1058
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research article Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation
Patrick Ng, Chia-Lin Wei, Wing-Kin Sung, Kuo Ping Chiu, Leonard Lipovich, Chin Chin Ang, Sanjay Gupta, Atif Shahab, Azmi Ridwan, Chee Hong Wong, Edison T Liu and Yijun Ruan Nature Methods2, 105–111
(February 2005); doi:10.1038/nmeth733
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news and views Transcriptome PETs: A genome's best friends
Brock A Peters and Victor E Velculescu Nature Methods2, 93–94
(February 2005); doi:10.1038/nmeth0205-93
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letters to nature Interaction network containing conserved and essential protein complexes in Escherichia coli
Gareth Butland, José Manuel Peregrín-Alvarez, Joyce Li, Wehong Yang, Xiaochun Yang, Veronica Canadien, Andrei Starostine, Dawn Richards, Bryan Beattie, Nevan Krogan, Michael Davey, John Parkinson , Jack Greenblatt and Andrew Emili Nature433, 531–537
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research article Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
John Rush, Albrecht Moritz, Kimberly A Lee, Ailan Guo, Valerie L Goss, Erik J Spek, Hui Zhang, Xiang-Ming Zha, Roberto D Polakiewicz and Michael J Comb Nature Biotechnology23, 94–101
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news and views An enriched look at tyrosine phosphorylation
Thomas P Conrads and Timothy D Veenstra Nature Biotechnology23, 36–37
(January 2005); doi:10.1038/nbt0105-36
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article Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment
Jonghwan Kim, Akshay A Bhinge, Xochitl C Morgan and Vishwanath R Iyer Nature Methods2, 47–53
(January 2005); doi:10.1038/nmeth726
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review article Data integration: challenges for drug discovery
David B. Searls Nature Reviews Drug Discovery4, 45–58
(January 2005); doi:10.1038/nrd1608
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article An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
Alejandro Sweet-Cordero, Sayan Mukherjee, Aravind Subramanian, Han You, Jeffrey J Roix, Christine Ladd-Acosta, Jill Mesirov, Todd R Golub and Tyler Jacks Nature Genetics37, 48–55
(January 2005); doi:10.1038/ng1490
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news and views Cross-species comparisons of cancer signaling
Thomas G Graeber and Charles L Sawyers Nature Genetics37, 7–8
(January 2005); doi:10.1038/ng0105-7
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review article Drosophila, the golden bug, emerges as a tool for human genetics
Ethan Bier Nature Reviews Genetics6, 9–23
(January 2005); doi:10.1038/nrg1503
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Ule, Joanna Spencer, Alan Williams, Jing-Shan Hu, Melissa Cline, Hui Wang, Tyson Clark, Claire Fraser, Matteo Ruggiu, Barry R Zeeberg, David Kane, John N Weinstein, John Blume and Robert B Darnell