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Research library: Systems biology/High-throughput

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review
Turning enzymes ON with small molecules
Julie A Zorn & James A Wells
Nature Chemical Biology 6, 179–188
(March 2010); doi:10.1038/nchembio.318
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review
Target-enrichment strategies for next-generation sequencing
Lira Mamanova et al.
Nature Methods 7, 111–118
(February 2010); doi:10.1038/nmeth.1419
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brief communication
In vivo selection of tumor-targeting RNA motifs
Jing Mi et al.
Nature Chemical Biology 6, 22–24
(January 2010); doi:10.1038/nchembio.277
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review
Pairing computation with experimentation: a powerful coupling for understanding T cell signalling
Arup K. Chakraborty & Jayajit Das
Nature Reviews Immunology 10, 59–71
(January 2010); doi:10.1038/nri2688
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analysis
A census of amplified and overexpressed human cancer genes
Thomas Santarius, Janet Shipley, Daniel Brewer, Michael R. Stratton & Colin S. Cooper
Nature Reviews Cancer 10, 59–64
(January 2010); doi:10.1038/nrc2771
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article
Automatic policing of biochemical annotations using genomic correlations
Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer & Dennis Vitkup
Nature Chemical Biology 6, 34–40
(January 2010); doi:10.1038/nchembio.266
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news and views
Biochemical networks: The evolution of gene annotation
Simon Kasif & Martin Steffen
Nature Chemical Biology 6, 4–5
(January 2010); doi:10.1038/nchembio.288
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review
RNA processing and its regulation: global insights into biological networks
Donny D. Licatalosi & Robert B. Darnell
Nature Reviews Genetics 11, 75–87
(January 2010); doi:10.1038/nrg2673
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