Research library: Techniques
2009:
| December
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Other Years: 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008
December
brief communication
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
Rupali P Patwardhan et al.
Nature Biotechnology 27, 1173–1175
(December 2009); doi:10.1038/nbt.1589
| Summary | Full Text (HTML / PDF) |
article
An auxin-based degron system for the rapid depletion of proteins in nonplant cells
Kohei Nishimura, Tatsuo Fukagawa, Haruhiko Takisawa, Tatsuo Kakimoto & Masato Kanemaki
Nature Methods 6, 917–922
(December 2009); doi:10.1038/nmeth.1401
| Summary | Full Text (HTML / PDF) |
article
Detection of sequential polyubiquitylation on a millisecond timescale
Nathan W. Pierce, Gary Kleiger, Shu-ou Shan & Raymond J. Deshaies
Nature 462, 615–619
(03 December 2009); doi:10.1038/nature08595
| Full Text (HTML / PDF) |
news and views
Cell biology: Stairway to the proteasome
Malavika Raman & J. Wade Harper
Nature 462, 585–586
(03 December 2009); doi:10.1038/462585a
| Full Text (HTML / PDF) |
November
analysis
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer
Xiao-Song Wang et al.
Nature Biotechnology 27, 1005–1011
(November 2009); doi:10.1038/nbt.1584
| Summary | Full Text (HTML / PDF) |
review
NMR spectroscopy brings invisible protein states into focus
Andrew J Baldwin & Lewis E Kay
Nature Chemical Biology 5, 808–814
(November 2009); doi:10.1038/nchembio.238
| Summary | Full Text (HTML / PDF) |
article
Visual proteomics of the human pathogen Leptospira interrogans
Martin Beck et al.
Nature Methods 6, 817–823
(November 2009); doi:10.1038/nmeth.1390
| Summary | Full Text (HTML / PDF) |
news and views
Adding a spatial dimension to the proteome
Kay Grünewald
Nature Methods 6, 798–800
(November 2009); doi:10.1038/nmeth1109-798
| Full Text (HTML / PDF) |
article
Emergent bistability by a growth-modulating positive feedback circuit
Cheemeng Tan, Philippe Marguet & Lingchong You
Nature Chemical Biology 5, 842–848
(November 2009); doi:10.1038/nchembio.218
| Summary | Full Text (HTML / PDF) |
article
Engineering splicing factors with designed specificities
Yang Wang, Cheom-Gil Cheong, Traci M Tanaka Hall & Zefeng Wang
Nature Methods 6, 825–830
(November 2009); doi:10.1038/nmeth.1379
| Summary | Full Text (HTML / PDF) |
article
Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer
Juan José Fung et al.
The EMBO Journal 28, 3315–3328
(November 2009); doi:10.1038/emboj.2009.267
| Summary | Full Text (HTML / PDF) |
article
'Edgetic' perturbation of a C. elegans BCL2 ortholog
Matija Dreze et al.
Nature Methods 6, 843–849
(November 2009); doi:10.1038/nmeth.1394
| Summary | Full Text (HTML / PDF) |
brief communication
A general life-death selection strategy for dissecting protein functions
Po Hien Ear & Stephen W Michnick
Nature Methods 6, 813–816
(November 2009); doi:10.1038/nmeth.1389
| Summary | Full Text (HTML / PDF) |
news and views
You too can play with an edge
Michael Costanzo, Anastasia Baryshnikova, Corey Nislow, Brenda Andrews & Charles Boone
Nature Methods 6, 797–798
(November 2009); doi:10.1038/nmeth1109-797
| Full Text (HTML / PDF) |
October
letter
Induction of protein-protein interactions in live cells using light
Masayuki Yazawa, Amir M Sadaghiani, Brian Hsueh & Ricardo E Dolmetsch
Nature Biotechnology 27, 941–945
(October 2009); doi:10.1038/nbt.1569
| Summary | Full Text (HTML / PDF) |
letter
A proteomics approach to discovering natural products and their biosynthetic pathways
Stefanie B Bumpus, Bradley S Evans, Paul M Thomas, Ioanna Ntai & Neil L Kelleher
Nature Biotechnology 27, 951–956
(October 2009); doi:10.1038/nbt.1565
| Summary | Full Text (HTML / PDF) |
article
Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms
Tim van Opijnen, Kip L Bodi & Andrew Camilli
Nature Methods 6, 767–772
(October 2009); doi:10.1038/nmeth.1377
| Summary | Full Text (HTML / PDF) |
article
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification
Kazuishi Kubota et al.
Nature Biotechnology 27, 933–940
(October 2009); doi:10.1038/nbt.1566
| Summary | Full Text (HTML / PDF) |
news and views
Snapshots of kinase activities
Javier Muñoz & Albert J R Heck
Nature Biotechnology 27, 912–913
(October 2009); doi:10.1038/nbt1009-912
| Full Text (HTML / PDF) |
brief communication
Proteomics strategy for quantitative protein interaction profiling in cell extracts
Kirti Sharma et al.
Nature Methods 6, 741–744
(October 2009); doi:10.1038/nmeth.1373
| Summary | Full Text (HTML / PDF) |
brief communication
Augmented photoswitching modulates immune signaling
Yixin Zhang, Frank Erdmann & Gunter Fischer
Nature Chemical Biology 5, 724–726
(October 2009); doi:10.1038/nchembio.214
| Summary | Full Text (HTML / PDF) |
letter
Spatiotemporal control of cell signalling using a light-switchable protein interaction
Anselm Levskaya, Orion D. Weiner, Wendell A. Lim & Christopher A. Voigt
Nature 461, 997–1001
(15 October 2009); doi:10.1038/nature08446
| Full Text (HTML / PDF) |
brief communication
Cell-selective metabolic labeling of proteins
John T Ngo et al.
Nature Chemical Biology 5, 715–717
(October 2009); doi:10.1038/nchembio.200
| Summary | Full Text (HTML / PDF) |
review
Engineering lymphocyte subsets: tools, trials and tribulations
Carl H. June, Bruce R. Blazar & James L. Riley
Nature Reviews Immunology 9, 704–716
(October 2009); doi:10.1038/nri2635
| Summary | Full Text (HTML / PDF) |
commentary
Engineered fluorescent proteins: innovations and applications
Michael W Davidson & Robert E Campbell
Nature Methods 6, 713–717
(October 2009); doi:10.1038/nmeth1009-713
| Summary | Full Text (HTML / PDF) |
brief communication
Augmented photoswitching modulates immune signaling
Yixin Zhang, Frank Erdmann & Gunter Fischer
Nature Chemical Biology 5, 724–726
(October 2009); doi:10.1038/nchembio.214
| Summary | Full Text (HTML / PDF) |
brief communication
Genetically encoded FRET sensors to monitor intracellular Zn2+ homeostasis
Jan L Vinkenborg et al.
Nature Methods 6, 737–740
(October 2009); doi:10.1038/nmeth.1368
| Summary | Full Text (HTML / PDF) |
September
review
Applying mass spectrometry-based proteomics to genetics, genomics and network biology
Matthias Gstaiger & Ruedi Aebersold
Nature Reviews Genetics 10, 617–627
(September 2009); doi:10.1038/nrg2633
| Summary | Full Text (HTML / PDF) |
analysis
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
Kai Wang et al.
Nature Biotechnology 27, 829–837
(September 2009); doi:10.1038/nbt.1563
| Summary | Full Text (HTML / PDF) |
brief communication
Modular scanning FCS quantifies receptor-ligand interactions in living multicellular organisms
Jonas Ries, Shuizi Rachel Yu, Markus Burkhardt, Michael Brand & Petra Schwille
Nature Methods 6, 643–645
(September 2009); doi:10.1038/nmeth.1355
| Summary | Full Text (HTML / PDF) |
brief communication
Membrane-bound FRET probe visualizes MMP12 activity in pulmonary inflammation
Amanda Cobos-Correa, Johanna B Trojanek, Stefanie Diemer, Marcus A Mall & Carsten Schultz
Nature Chemical Biology 5, 628–630
(September 2009); doi:10.1038/nchembio.196
| Summary | Full Text (HTML / PDF) |
article
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors
Justin P Dassie et al.
Nature Biotechnology 27, 839–846
(September 2009); doi:10.1038/nbt.1560
| Summary | Full Text (HTML / PDF) |
news and views
Silencing prostate cancer
Ivanka Toudjarska & Antonin de Fougerolles
Nature Biotechnology 27, 821–823
(September 2009); doi:10.1038/nbt0909-821
| Full Text (HTML / PDF) |
letter
Coordination of Rho GTPase activities during cell protrusion
Matthias Machacek et al.
Nature 461, 99–103
(03 September 2009); doi:10.1038/nature08242
| Full Text (HTML / PDF) |
letter
A genetically encoded photoactivatable Rac controls the motility of living cells
Yi I. Wu et al.
Nature 461, 104–108
(03 September 2009); doi:10.1038/nature08241
| Full Text (HTML / PDF) |
review
Microfluidic devices for measuring gene network dynamics in single cells
Matthew R. Bennett & Jeff Hasty
Nature Reviews Genetics 10, 628–638
(September 2009); doi:10.1038/nrg2625
| Summary | Full Text (HTML / PDF) |
article
A 3D digital atlas of C. elegans and its application to single-cell analyses
Fuhui Long, Hanchuan Peng, Xiao Liu, Stuart K Kim & Eugene Myers
Nature Methods 6, 667–672
(September 2009); doi:10.1038/nmeth.1366
| Summary | Full Text (HTML / PDF) |
news and views
Google 'EarthWorm'
William A Mohler
Nature Methods 6, 635–636
(September 2009); doi:10.1038/nmeth0909-635
| Full Text (HTML / PDF) |
review
Target profiling of small molecules by chemical proteomics
Uwe Rix & Giulio Superti-Furga
Nature Chemical Biology 5, 616–624
(September 2009); doi:10.1038/nchembio.216
| Summary | Full Text (HTML / PDF) |
August
letter
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
Hyenjong Hong et al.
Nature 460, 1132–1135
(27 August 2009); doi:10.1038/nature08235
| Full Text (HTML / PDF) |
letter
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Han Li et al.
Nature 460, 1136–1139
(27 August 2009); doi:10.1038/nature08290
| Full Text (HTML / PDF) |
letter
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
Teruhisa Kawamura et al.
Nature 460, 1140–1144
(27 August 2009); doi:10.1038/nature08311
| Full Text (HTML / PDF) |
letter
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
Jochen Utikal et al.
Nature 460, 1145–1148
(27 August 2009); doi:10.1038/nature08285
| Full Text (HTML / PDF) |
letter
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
Rosa M. Marión et al.
Nature 460, 1149–1153
(27 August 2009); doi:10.1038/nature08287
| Full Text (HTML / PDF) |
news and views
Stem cells: The promises and perils of p53
Valery Krizhanovsky & Scott W. Lowe
Nature 460, 1085–1086
(27 August 2009); doi:10.1038/4601085a
| Full Text (HTML / PDF) |
brief communication
Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions
Nelson P Barrera et al.
Nature Methods 6, 585–587
(August 2009); doi:10.1038/nmeth.1347
| Summary | Full Text (HTML / PDF) |
technical report
Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis
Manav Korpal et al.
Nature Medicine 15, 960–966
(August 2009); doi:10.1038/nm.1943
| Summary | Full Text (HTML / PDF) |
brief communication
Metabolic network analysis integrated with transcript verification for sequenced genomes
Ani Manichaikul et al.
Nature Methods 6, 589–592
(August 2009); doi:10.1038/nmeth.1348
| Summary | Full Text (HTML / PDF) |
technical report
Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes
Laura E Edgington et al.
Nature Medicine 15, 967–973
(August 2009); doi:10.1038/nm.1938
| Summary | Full Text (HTML / PDF) |
article
Synthetic protein scaffolds provide modular control over metabolic flux
John E Dueber et al.
Nature Biotechnology 27, 753–759
(August 2009); doi:10.1038/nbt.1557
| Summary | Full Text (HTML / PDF) |
news and views
Synthetic metabolic pipelines
Matthew P DeLisa & Robert J Conrado
Nature Biotechnology 27, 728–729
(August 2009); doi:10.1038/nbt0809-728
| Full Text (HTML / PDF) |
article
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
Greg L Hura et al.
Nature Methods 6, 606–612
(August 2009); doi:10.1038/nmeth.1353
| Summary | Full Text (HTML / PDF) |
July
research
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma
Terri A Addona et al.
Nature Biotechnology 27, 633–641
(July 2009); doi:10.1038/nbt.1546
| Summary | Full Text (HTML / PDF) |
news and views
Biomarker validation by targeted mass spectrometry
Martin McIntosh & Matthew Fitzgibbon
Nature Biotechnology 27, 622–623
(July 2009); doi:10.1038/nbt0709-622
| Full Text (HTML / PDF) |
brief communication
'Injecting' yeast
Daniel Riveline & Paul Nurse
Nature Methods 6, 513–514
(July 2009); doi:10.1038/nmeth.1335
| Summary | Full Text (HTML / PDF) |
article
Quantifying biogenic bias in screening libraries
Jérôme Hert, John J Irwin, Christian Laggner, Michael J Keiser & Brian K Shoichet
Nature Chemical Biology 5, 479–483
(July 2009); doi:10.1038/nchembio.180
| Summary | Full Text (HTML / PDF) |
review
Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds
Yan Feng, Timothy J. Mitchison, Andreas Bender, Daniel W. Young & John A. Tallarico
Nature Reviews Drug Discovery 8, 567–578
(July 2009); doi:10.1038/nrd2876
| Summary | Full Text (HTML / PDF) |
article
Doxycycline-dependent photoactivated gene expression in eukaryotic systems
Sidney B Cambridge et al.
Nature Methods 6, 527–531
(July 2009); doi:10.1038/nmeth.1340
| Summary | Full Text (HTML / PDF) |
article
Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug
Jennifer A MacDiarmid et al.
Nature Biotechnology 27, 643–651
(July 2009); doi:10.1038/nbt.1547
| Summary | Full Text (HTML / PDF) |
news and views
Minicells overcome tumor drug-resistance
Emmanouil D Karagiannis & Daniel G Anderson
Nature Biotechnology 27, 620–621
(July 2009); doi:10.1038/nbt0709-620
| Full Text (HTML / PDF) |
article
Mapping the structure and conformational movements of proteins with transition metal ion FRET
Justin W Taraska, Michael C Puljung, Nelson B Olivier, Galen E Flynn & William N Zagotta
Nature Methods 6, 532–537
(July 2009); doi:10.1038/nmeth.1341
| Summary | Full Text (HTML / PDF) |
article
Phage-encoded combinatorial chemical libraries based on bicyclic peptides
Christian Heinis, Trevor Rutherford, Stephan Freund & Greg Winter
Nature Chemical Biology 5, 502–507
(July 2009); doi:10.1038/nchembio.184
| Summary | Full Text (HTML / PDF) |
news and views
Encoding chemistry
Dario Neri & André W Brändli
Nature Chemical Biology 5, 452–453
(July 2009); doi:10.1038/nchembio0709-452
| Full Text (HTML / PDF) |
brief communication
Protein interaction platforms: visualization of interacting proteins in yeast
Alexa M Schmitz, Monica F Morrison, Akochi O Agunwamba, Max L Nibert & Cammie F Lesser
Nature Methods 6, 500–502
(July 2009); doi:10.1038/nmeth.1337
| Summary | Full Text (HTML / PDF) |
June
brief communication
Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture
Michael T Forrester et al.
Nature Biotechnology 27, 557–559
(June 2009); doi:10.1038/nbt.1545
| Summary | Full Text (HTML / PDF) |
review
High-throughput insertional mutagenesis screens in mice to identify oncogenic networks
Jaap Kool & Anton Berns
Nature Reviews Cancer 9, 389–399
(June 2009); doi:10.1038/nrc2647
| Summary | Full Text (HTML / PDF) |
brief communication
A new screening assay for allosteric inhibitors of cSrc
Jeffrey R Simard et al.
Nature Chemical Biology 5, 394–396
(June 2009); doi:10.1038/nchembio.162
| Summary | Full Text (HTML / PDF) |
May
article
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
Kosuke Yusa, Roland Rad, Junji Takeda & Allan Bradley
Nature Methods 6, 363–369
(May 2009); doi:10.1038/nmeth.1323
| Summary | Full Text (HTML / PDF) |
news and views
Without a trace? PiggyBac-ing toward pluripotency
Matthias Stadtfeld & Konrad Hochedlinger
Nature Methods 6, 329–330
(May 2009); doi:10.1038/nmeth0509-329
| Full Text (HTML / PDF) |
technical report
Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens
Alice C Fan et al.
Nature Medicine 15, 566–571
(May 2009); doi:10.1038/nm.1903
| Summary | Full Text (HTML / PDF) |
article
Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency
Akitsu Hotta et al.
Nature Methods 6, 370–376
(May 2009); doi:10.1038/nmeth.1325
| Summary | Full Text (HTML / PDF) |
article
Molecular docking and ligand specificity in fragment-based inhibitor discovery
Yu Chen & Brian K Shoichet
Nature Chemical Biology 5, 358–364
(May 2009); doi:10.1038/nchembio.155
| Summary | Full Text (HTML / PDF) |
news and views
Fragment-based drug discovery takes a virtual turn
Maurizio Pellecchia
Nature Chemical Biology 5, 274–275
(May 2009); doi:10.1038/nchembio0509-274
| Full Text (HTML / PDF) |
April
letter
Temporally precise in vivo control of intracellular signalling
Raag D. Airan, Kimberly R. Thompson, Lief E. Fenno, Hannah Bernstein & Karl Deisseroth
Nature 458, 1025–1029
(23 April 2009); doi:10.1038/nature07926
| Summary | Full Text (HTML / PDF) |
news and views
Neuroscience: Optical control of reward
David E. Moorman & Gary Aston-Jones
Nature 458, 980–981
(23 April 2009); doi:10.1038/458980a
| Full Text (HTML / PDF) |
article
Analysis of the eukaryotic prenylome by isoprenoid affinity tagging
Uyen T T Nguyen et al.
Nature Chemical Biology 5, 227–235
(April 2009); doi:10.1038/nchembio.149
| Summary | Full Text (HTML / PDF) |
news and views
Getting a handle on protein prenylation
James L Hougland & Carol A Fierke
Nature Chemical Biology 5, 197–198
(April 2009); doi:10.1038/nchembio0409-197
| Full Text (HTML / PDF) |
perspective
Lymphocyte signaling: beyond knockouts
Alexander Saveliev & Victor L J Tybulewicz
Nature Immunology 10, 361–364
(April 2009); doi:10.1038/ni.1709
| Summary | Full Text (HTML / PDF) |
letter
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
Knut Woltjen et al.
Nature 458, 766–770
(09 April 2009); doi:10.1038/nature07863
| Summary | Full Text (HTML / PDF) |
letter
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
Keisuke Kaji et al.
Nature 458, 771–775
(09 April 2009); doi:10.1038/nature07864
| Summary | Full Text (HTML / PDF) |
news and views
Stem Cells: Low-risk reprogramming
Martin F. Pera
Nature 458, 715–716
(09 April 2009); doi:10.1038/458715a
| Full Text (HTML / PDF) |
brief communication
SUnSET, a nonradioactive method to monitor protein synthesis
Enrico K Schmidt et al.
Nature Methods 6, 275–277
(April 2009); doi:10.1038/nmeth.1314
| Summary | Full Text (HTML / PDF) |
March
article
Analysis of receptor oligomerization by FRAP microscopy
Sandra Dorsch, Karl-Norbert Klotz, Stefan Engelhardt, Martin J Lohse & Moritz Bünemann
Nature Methods 6, 225–230
(March 2009); doi:10.1038/nmeth.1304
| Summary | Full Text (HTML / PDF) |
article
The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis
Moritz Mickler, Martin Hessling, Christoph Ratzke, Johannes Buchner & Thorsten Hugel
Nature Structural & Molecular Biology 16, 281–286
(March 2009); doi:10.1038/nsmb.1557
| Summary | Full Text (HTML / PDF) |
article
Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90
Martin Hessling, Klaus Richter & Johannes Buchner
Nature Structural & Molecular Biology 16, 287–293
(March 2009); doi:10.1038/nsmb.1565
| Summary | Full Text (HTML / PDF) |
news and views
Visualizing the twists and turns of a molecular chaperone
Len Neckers, Shinji Tsutsumi & Mehdi Mollapour
Nature Structural & Molecular Biology 16, 235–236
(March 2009); doi:10.1038/nsmb0309-235
| Full Text (HTML / PDF) |
brief communication
Quantitative interaction proteomics using mass spectrometry
Alexander Wepf, Timo Glatter, Alexander Schmidt, Ruedi Aebersold & Matthias Gstaiger
Nature Methods 6, 203–205
(March 2009); doi:10.1038/nmeth.1302
| Summary | Full Text (HTML / PDF) |
February
letter
Direct observation of the nanoscale dynamics of membrane lipids in a living cell
Christian Eggeling et al.
Nature 457, 1159–1162
(26 February 2009); doi:10.1038/nature07596
| Summary | Full Text (HTML / PDF) |
brief communication
In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts
Jean Y Perentes et al.
Nature Methods 6, 143–145
(February 2009); doi:10.1038/nmeth.1295
| Summary | Full Text (HTML / PDF) |
article
Monomeric fluorescent timers that change color from blue to red report on cellular trafficking
Fedor V Subach et al.
Nature Chemical Biology 5, 118–126
(February 2009); doi:10.1038/nchembio.138
| Summary | Full Text (HTML / PDF) |
news and views
Fluorescent timers shine a light on protein trafficking
Emre Dikici & Sylvia Daunert
Nature Chemical Biology 5, 70–71
(February 2009); doi:10.1038/nchembio0209-70
| Full Text (HTML / PDF) |
letter
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex
Tijana Jovanovic-Talisman et al.
Nature 457, 1023–1027
(19 February 2009); doi:10.1038/nature07600
| Summary | Full Text (HTML / PDF) |
article
A genetically encoded fluorescent reporter of ATP:ADP ratio
Jim Berg, Yin Pun Hung & Gary Yellen
Nature Methods 6, 161–166
(February 2009); doi:10.1038/nmeth.1288
| Summary | Full Text (HTML / PDF) |
brief communication
Large-scale profiling of protein palmitoylation in mammalian cells
Brent R Martin & Benjamin F Cravatt
Nature Methods 6, 135–138
(February 2009); doi:10.1038/nmeth.1293
| Summary | Full Text (HTML / PDF) |
January
letter
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
Adlen Foudi et al.
Nature Biotechnology 27, 84–90
(January 2009); doi:10.1038/nbt.1517
| Summary | Full Text (HTML / PDF) |
brief communication
An in vitro microfluidic approach to generating protein-interaction networks
Doron Gerber, Sebastian J Maerkl & Stephen R Quake
Nature Methods 6, 71–74
(January 2009); doi:10.1038/nmeth.1289
| Summary | Full Text (HTML / PDF) |
article
High-resolution mapping of copy-number alterations with massively parallel sequencing
Derek Y Chiang et al.
Nature Methods 6, 99–103
(January 2009); doi:10.1038/nmeth.1276
| Summary | Full Text (HTML / PDF) |
brief communication
Stable knockdown of microRNA in vivo by lentiviral vectors
Bernhard Gentner et al.
Nature Methods 6, 63–66
(January 2009); doi:10.1038/nmeth.1277
| Summary | Full Text (HTML / PDF) |
letter
A tunable synthetic mammalian oscillator
Marcel Tigges, Tatiana T. Marquez-Lago, Jörg Stelling & Martin Fussenegger
Nature 457, 309–312
(15 January 2009); doi:10.1038/nature07616
| Summary | Full Text (HTML / PDF) |
news and views
Synthetic biology: The yin and yang of nature
Jeff Gore & Alexander van Oudenaarden
Nature 457, 271–272
(15 January 2009); doi:10.1038/457271a
| Full Text (HTML / PDF) |
letter
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
Jinyan Du et al.
Nature Biotechnology 27, 77–83
(January 2009); doi:10.1038/nbt.1513
| Summary | Full Text (HTML / PDF) |
brief communication
Integrated network analysis platform for protein-protein interactions
Jianmin Wu et al.
Nature Methods 6, 75–77
(January 2009); doi:10.1038/nmeth.1282
| Summary | Full Text (HTML / PDF) |
letter
Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis
Jiyun V. Kim, Silvia S. Kang, Michael L. Dustin & Dorian B. McGavern
Nature 457, 191–195
(08 January 2009); doi:10.1038/nature07591
| Summary | Full Text (HTML / PDF) |
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