letters to nature Role for a Drosophila Myb-containing protein complex in site-specific DNA replication
Eileen L. Beall, J. Robert Manak, Sharleen Zhou, Maren Bell, Joseph S. Lipsick and Michael R. Botchan Nature420, 833–837
(19 December 2002); doi:10.1038/nature01228
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news and views Crowd control in the crypt
Catherine Booth, Gerard Brady and Christopher S. Potten Nature Medicine8, 1360–1361
(December 2002); doi:10.1038/nm1202-1360
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brief communication Pointed and Tramtrack69 establish an EGFR-dependent transcriptional switch to regulate mitosis
Antonio Baonza, Christopher M. Murawsky, Andrew A. Travers and Matthew Freeman Nature Cell Biology4, 976–980
(December 2002); doi:10.1038/ncb887
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article Induction of angiogenesis in a mouse model using engineered transcription factors
Edward J. Rebar, Yan Huang, Reed Hickey, Anjali K. Nath, David Meoli, Sameer Nath, Bingliang Chen, Lei Xu, Yuxin Liang, Andrew C. Jamieson, Lei Zhang, S Kaye Spratt, Casey C. Case, Alan Wolffe and Frank J. Giordano Nature Medicine8, 1427–1432
(December 2002); doi:10.1038/nm795
| Abstract | Full Text (HTML/PDF) |
news and views Vessel maneuvers: Zinc fingers promote angiogenesis
Renata Pasqualini, Carlos F. Barbas and III Wadih Arap Nature Medicine8, 1353–1354
(December 2002); doi:10.1038/nm1202-1353
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review article Regulation of transcription factors by neuronal activity
Anne E. West, Eric C. Griffith and Michael E. Greenberg Nature Reviews Neuroscience3, 921–931
(December 2002); doi:10.1038/nrn987
| Summary | Full Text (HTML / PDF) |
November
letters to nature TRF2 associates with DREF and directs promoter-selective gene expression in Drosophila
Andreas Hochheimer, Sharleen Zhou, Shuang Zheng, Michael C. Holmes and Robert Tjian Nature420, 439–445
(28 November 2002); doi:10.1038/nature01167
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news and views Circadian rhythms: The cancer connection
Michael Rosbash and Joseph S. Takahashi Nature420, 373–374
(28 November 2002); doi:10.1038/420373a
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article BID regulation by p53 contributes to chemosensitivity
Joanna K. Sax, Peiwen Fei, Maureen E. Murphy, Eric Bernhard, Stanley J. Korsmeyer and Wafik S. El-Deiry Nature Cell Biology4, 842–849
(November 2002); doi:10.1038/ncb866
| Abstract | Full Text (HTML/PDF) |
news and views Developmental biology: Colon construction
Mark Peifer Nature420, 274–276
(21 November 2002); doi:10.1038/420274a
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article Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
Gina Balciunaite, Marcel P. Keller, Egle Balciunaite, Luca Piali, Saulius Zuklys, Yves D. Mathieu, Jason Gill, Richard Boyd, Daniel J. Sussman and Georg A. Holländer Nature Immunology3, 1102–1108
(November 2002); doi:10.1038/ni850
| Abstract | Full Text (HTML/PDF) |
letters to nature The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease
Sawsan Youssef, Olaf Stüve, Juan C. Patarroyo, Pedro J. Ruiz, Jennifer L. Radosevich, Eun Mi Hur, Manuel Bravo, Dennis J. Mitchell, Raymond A. Sobel, Lawrence Steinman and Scott S. Zamvil Nature420, 78–84
(07 November 2002); doi:10.1038/nature01158
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news and views Medicine: Tackling multiple sclerosis
Hartmut Wekerle Nature420, 39–40
(07 November 2002); doi:10.1038/420039a
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article Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
Motoaki Sano, Maha Abdellatif, Hidemasa Oh, Min Xie, Luigi Bagella, Antonio Giordano, Lloyd H. Michael, Francesco J. DeMayo and Michael D. Schneider Nature Medicine8, 1310–1317
(November 2002); doi:10.1038/nm778
| Abstract | Full Text (HTML/PDF) |
original paper Regulation of the IRF-1 tumour modifier during the response to genotoxic stress involves an ATM-dependent signalling pathway
Jessica Pamment, Eleanor Ramsay, Michael Kelleher, David Dornan & Kathryn L Ball Oncogene21, 7776–7785
(7 November 2002); doi:10.1038/sj.onc.1205981
| Abstract |
October
letters to nature Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage
Joan Seoane, Hong-Van Le and Joan Massagué Nature419, 729–734
(17 October 2002); doi:10.1038/nature01119
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letters to nature A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis
Lawryn H. Kasper, Fayçal Boussouar, Paul A. Ney, Carl W. Jackson, Jerold Rehg, Jan M. van Deursen and Paul K. Brindle Nature419, 738–743
(17 October 2002); doi:10.1038/nature01062
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article Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-a-inducible genes
Mei Huang, Feng Qian, Yuanyu Hu, Chengeng Ang, Zhong Li and Zilong Wen Nature Cell Biology4, 774–781
(October 2002); doi:10.1038/ncb855
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article Regulation of insulin action and pancreatic b-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
Jun Nakae, William H. Biggs, III Tadahiro Kitamura, Webster K. Cavenee, Christopher V.E. Wright, Karen C. Arden and Domenico Accili Nature Genetics32, 245–253
(October 2002); doi:10.1038/ng890
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letter Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
Shinji Kondo, Brian C. Schutte, Rebecca J. Richardson, Bryan C. Bjork, Alexandra S. Knight, Yoriko Watanabe, Emma Howard, Renata L.L. Ferreira de Lima, Sandra Daack-Hirsch, Achim Sander, Donna M. McDonald-McGinn, Elaine H. Zackai, Edward J. Lammer, Arthur S. Aylsworth, Holly H. Ardinger, Andrew C. Lidral, Barbara R. Pober, Lina Moreno, Mauricio Arcos-Burgos, Consuelo Valencia, Claude Houdayer, Michel Bahuau, Danilo Moretti-Ferreira, Antonio Richieri-Costa, Michael J. Dixon and Jeffrey C. Murray Nature Genetics32, 285–289
(October 2002); doi:10.1038/ng985
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news and views The pit, the cleft and the web
Maximilian Muenke Nature Genetics32, 219–220
(October 2002); doi:10.1038/ng1002-219
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review article Emerging roles of PPARs in inflammation and immunity
Raymond A. Daynes and Dallas C. Jones Nature Reviews Immunology2, 748–759
(October 2002); doi:10.1038/nri912
| Summary | Full Text (HTML / PDF) |
review article Transcription factors as targets for cancer therapy
James E. Darnell Jr, Nature Reviews Cancer2, 740–749
(October 2002); doi:10.1038/nrc906
| Summary | Full Text (HTML / PDF) |
article Evidence for two apoptotic pathways in light-induced retinal degeneration
Wenshan Hao, Andreas Wenzel, Martin S. Obin, Ching-Kang Chen, Elliott Brill, Nataliia V. Krasnoperova, Pamela Eversole-Cire, Yelena Kleyner, Allen Taylor, Melvin I. Simon, Christian Grimm, Charlotte E. Remé and Janis Lem Nature Genetics32, 254–260
(October 2002); doi:10.1038/ng984
| Abstract | Full Text (HTML/PDF) |
news and views Blinded by the light
Samuel G. Jacobson and Roderick R. McInnes Nature Genetics32, 215–216
(October 2002); doi:10.1038/ng1002-215
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review article NF-κB regulation in the immune system
Qiutang Li and Inder M. Verma Nature Reviews Immunology2, 725–734
(October 2002); doi:10.1038/nri910
| Summary | Full Text (HTML / PDF) |
letter Human securin interacts with p53 and modulates p53-mediated transcriptional activity and apoptosis
Juan A. Bernal, Rosa Luna, Águeda Espina, Icíar Lázaro, Francisco Ramos-Morales, Francisco Romero, Carmen Arias, Augusto Silva, María Tortolero and José A. Pintor-Toro Nature Genetics32, 306–311
(October 2002); doi:10.1038/ng997
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news and views Securin a new role for itself
Anil K. Rustgi Nature Genetics32, 222–224
(October 2002); doi:10.1038/ng1002-222
| Full Text (HTML/PDF) |
original paper Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-β and bone morphogenetic protein
Kyeong-Sook Lee, Seung-Hyun Hong & Suk-Chul Bae Oncogene21, 7156–7163
(17 October 2002); doi:10.1038/sj.onc.1205937
| First Paragraph |
brief communication Astral microtubules monitor metaphase spindle alignment in fission yeast
Snezhana Oliferenko and Mohan K. Balasubramanian Nature Cell Biology4, 816–820
(October 2002); doi:10.1038/ncb861
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news and views First things first: spindle orientation and mitotic progression
Dannel McCollum Nature Cell Biology4, E225
(October 2002); doi:10.1038/ncb1002-e225
| Full Text (HTML/PDF) |
article Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice
Niall C. Tebbutt, Andrew S. Giraud, Melissa Inglese, Brendan Jenkins, Paul Waring, Fiona J. Clay, Sina Malki, Barbara M. Alderman, Dianne Grail, Frédéric Hollande, Joan K. Heath and Matthias Ernst Nature Medicine8, 1089–1097
(October 2002); doi:10.1038/nm763
| Abstract | Full Text (HTML/PDF) |
news and views Inflammation intersection: gp130 balances gut irritation and stomach cancer
Timothy C. Wang and James R. Goldenring Nature Medicine8, 1080–1082
(October 2002); doi:10.1038/nm1002-1080
| Full Text (HTML/PDF) |
September
review article STATS: transcriptional control and biological impact
David E. Levy and J. E. Darnell Jr Nature Reviews Molecular Cell Biology3, 651–662
(September 2002); doi:10.1038/nrm909
| Summary | Full Text (HTML / PDF) |
letter BRCA1 induces DNA damage recognition factors and enhances nucleotide excision repair
Anne-Renee Hartman and James M. Ford Nature Genetics32, 180–184
(September 2002); doi:10.1038/ng953
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letter Survival signaling mediated by c-Jun NH2-terminal kinase in transformed B lymphoblasts
Patricia Hess, German Pihan, Charles L. Sawyers, Richard A. Flavell and Roger J. Davis Nature Genetics32, 201–205
(September 2002); doi:10.1038/ng946
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letters to nature Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Geert J. P. L. Kops, Tobias B. Dansen, Paulien E. Polderman, Ingrid Saarloos, Karel W. A. Wirtz, Paul J. Coffer, Ting-T. Huang, Johannes L. Bos, René H. Medema and Boudewijn M. T. Burgering Nature419, 316–321
(19 September 2002); doi:10.1038/nature01036
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article Sensitization of IFN-g Jak-STAT signaling during macrophage activation
Xiaoyu Hu, Carmen Herrero, Wai-Ping Li, Taras T. Antoniv, Erik Falck-Pedersen, Alisa E. Koch, James M. Woods, G. Kenneth Haines and III Lionel B. Ivashkiv Nature Immunology3, 859–866
(September 2002); doi:10.1038/ni828
| Abstract | Full Text (HTML/PDF) |
letter Distinct in vivo requirements for establishment versus maintenance of transcriptional repression
John C. Wheeler, Christine VanderZwan, Xiaoti Xu, Deborah Swantek, W. Daniel Tracey and J. Peter Gergen Nature Genetics32, 206–210
(September 2002); doi:10.1038/ng942
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news and views Stopping transcription in its tracks
Barbara Jennings Nature Genetics32, 87–88
(September 2002); doi:10.1038/ng943
| Full Text (HTML/PDF) |
letters to nature SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals
Qi Xie, Hui-Shan Guo, Geza Dallman, Shengyun Fang, Allan M. Weissman and Nam-Hai Chua Nature419, 167–170
(12 September 2002); doi:10.1038/nature00998
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perspectives Timeline: Signalling through nuclear receptors
Jamshed R. Tata Nature Reviews Molecular Cell Biology3, 702–710
(September 2002); doi:10.1038/nrm914
| Abstract | Full Text (HTML/PDF) |
article A requirement for CARMA1 in TCR-induced NF-kB activation
Donghai Wang, Yun You, Sara M. Case, Linda M. McAllister-Lucas, Lin Wang, Peter S. DiStefano, Gabriel Nuńez, John Bertin and Xin Lin Nature Immunology3, 830–835
(September 2002); doi:10.1038/ni824
| Abstract | Full Text (HTML/PDF) |
article CARMA1 is a critical lipid raft-associated regulator of TCR-induced NF-kB activation
Olivier Gaide, Benoît Favier, Daniel F. Legler, David Bonnet, Brian Brissoni, Salvatore Valitutti, Claude Bron, Jürg Tschopp and Margot Thome Nature Immunology3, 836–843
(September 2002); doi:10.1038/ni830
| Abstract | Full Text (HTML/PDF) |
news and views Up the down staircase
David Wallach Nature Immunology3, 802–803
(September 2002); doi:10.1038/ni0902-802
| Full Text (HTML/PDF) |
review article Nf-kb, chemokine gene transcription and tumour growth
Ann Richmond Nature Reviews Immunology2, 664–674
(September 2002); doi:10.1038/nri887
| Abstract | Full Text (HTML/PDF) |
review article Strategies for mmp inhibition in cancer: innovations for the post-trial era
Christopher Mark Overall and Carlos López-Otín Nature Reviews Cancer2, 657–672
(September 2002); doi:10.1038/nrc884
| Summary | Full Text (HTML / PDF) |
news and views Chaperones and transcriptional regulation by nuclear receptors
Jason C. Young and F. Ulrich Hartl Nature Structural Biology9, 640–642
(September 2002); doi:10.1038/nsb0902-640
| Full Text (HTML/PDF) |
August
article Revealing modular organization in the yeast transcriptional network
Jan Ihmels, Gilgi Friedlander, Sven Bergmann, Ofer Sarig, Yaniv Ziv and Naama Barkai Nature Genetics31, 370–377
(August 2002); doi:10.1038/ng941
| Abstract | Full Text (HTML/PDF) |
letter Digenic inheritance of severe insulin resistance in a human pedigree
David B. Savage, Maura Agostini, Inês Barroso, Mark Gurnell, Jian'an Luan, Aline Meirhaeghe, Anne-Helen Harding, Gudrun Ihrke, Odelia Rajanayagam, Maria A. Soos, Stella George, Dirk Berger, E. Louise Thomas, Jimmy D. Bell, Karim Meeran, Richard J. Ross, Antonio Vidal-Puig, Nicholas J. Wareham, Stephen O'Rahilly, V. Krishna K. Chatterjee and Alan J. Schafer Nature Genetics31, 379–384
(August 2002); doi:10.1038/ng926
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letters to nature A component of the ARC/Mediator complex required for TGFb/Nodal signalling
Yoichi Kato, Raymond Habas, Yu Katsuyama, Anders M. Näär and Xi He Nature418, 641–646
(8 August 2002); doi:10.1038/nature00969
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News and Views MAPping p38 binding interactions
Elizabeth H. Cox Nature Structural Biology9, 569
(August 2002); doi:10.1038/nsb0802-569
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review article p73: Friend or foe in tumorigenesis
Gerry Melino, Vincenzo De Laurenzi and Karen H. Vousden Nature Reviews Cancer2, 605–615
(August 2002); doi:10.1038/nrc861
| Abstract | Full Text (HTML/PDF) |
article Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling
Takayuki Shindo, Ichiro Manabe, Yasushi Fukushima, Kazuyuki Tobe, Kenichi Aizawa, Saku Miyamoto, Keiko Kawai-Kowase, Nobuo Moriyama, Yasushi Imai, Hayato Kawakami, Hiroaki Nishimatsu, Takashi Ishikawa, Toru Suzuki, Hiroyuki Morita, Koji Maemura, Masataka Sata, Yasunobu Hirata, Masayuki Komukai, Hiroyuki Kagechika, Takashi Kadowaki, Masahiko Kurabayashi and Ryozo Nagai Nature Medicine8, 856–863
(August 2002); doi:10.1038/nm738
| Abstract | Full Text (HTML/PDF) |
July
brief communication Nucleophosmin regulates the stability and transcriptional activity of p53
Emanuela Colombo, Jean-Christophe Marine, Davide Danovi, Brunangelo Falini and Pier Giuseppe Pelicci Nature Cell Biology4, 529–533
(July 2002); doi:10.1038/ncb814
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article Hlx is induced by and genetically interacts with T-bet to promote heritable TH1 gene induction
Alan C. Mullen, Anne S. Hutchins, Frances A. High, Hubert W. Lee, Kara J. Sykes, Lewis A. Chodosh and Steven L. Reiner Nature Immunology3, 652–658
(July 2002); doi:10.1038/ni807
| Abstract | Full Text (HTML/PDF) |
article TH cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes
Orly Avni, Dong Lee, Fernando Macian, Susanne J. Szabo, Laurie H. Glimcher and Anjana Rao Nature Immunology3, 643–651
(July 2002); doi:10.1038/ni808
| Abstract | Full Text (HTML/PDF) |
article The t(8;21) fusion protein, AML1-ETO, specifically represses the transcription of the p14ARF tumor suppressor in acute myeloid leukemia
Bryan Linggi, Carsten Müller-Tidow, Louis van de Locht, Ming Hu, John Nip, Hubert Serve, Wolfgang E. Berdel, Bert van der Reijden, Dawn E. Quelle, Janet D. Rowley, John Cleveland, Joop H. Jansen, Pier Paolo Pandolfi and Scott W. Hiebert Nature Medicine8, 743–750
(July 2002); doi:10.1038/nm726
| Abstract | Full Text (HTML/PDF) |
news and views Burning up TNF toxicity for cancer therapy
Marcel Leist and Marja Jäättelä Nature Medicine8, 667–668
(July 2002); doi:10.1038/nm0702-667
| Full Text (HTML/PDF) |
letter Mutations in SUFU predispose to medulloblastoma
Michael D. Taylor, Ling Liu, Corey Raffel, Chi-chung Hui, Todd G. Mainprize, Xiaoyun Zhang, Ron Agatep, Sharon Chiappa, Luzhang Gao, Anja Lowrance, Aihau Hao, Alisa M. Goldstein, Theodora Stavrou, Stephen W. Scherer, Wieslaw T. Dura, Brandon Wainwright, Jeremy A. Squire, James T. Rutka and David Hogg Nature Genetics31, 306–310
(July 2002); doi:10.1038/ng916
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letter to nature Identification of genes expressed in C. elegans touch receptor neurons
Yun Zhang, Charles Ma, Thomas Delohery, Brian Nasipak, Barrett C. Foat, Alexander Bounoutas, Harmen J. Bussemaker, Stuart K. Kim and Martin Chalfie Nature418, 331–335
(18 July 2002); doi:10.1038/nature00891
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letter to nature Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes
Tian H. Chi, Mimi Wan, Keji Zhao, Ichiro Taniuchi, Lei Chen, Dan R. Littman and Gerald R. Crabtree Nature 418, 195–199
(11 July 2002); doi:10.1038/nature00876
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brief communication The role of NFAT transcription factors in integrin-mediated carcinoma invasion
Sebastien Jauliac, Cristina López-Rodriguez, Leslie M. Shaw, Lawrence F. Brown, Anjana Rao and Alex Toker Nature Cell Biology4, 540–544
(July 2002); doi:10.1038/ncb816
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brief communication Nuclear exclusion of Smad2 is a mechanism leading to loss of competence
Oliver H. Grimm and J. B. Gurdon Nature Cell Biology4, 519–522
(July 2002); doi:10.1038/ncb812
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article Loss of HIF-2a and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
Veerle Compernolle, Koen Brusselmans, Till Acker, Peter Hoet, Marc Tjwa, Heike Beck, Stéphane Plaisance, Yuval Dor, Eli Keshet, Florea Lupu, Benoit Nemery, Mieke Dewerchin, Paul Van Veldhoven, Karl Plate, Lieve Moons, Désiré Collen and Peter Carmeliet Nature Medicine8, 702–710
(July 2002); doi:10.1038/nm721
| Abstract | Full Text (HTML/PDF) |
article Genome-wide binding map of the histone deacetylase Rpd3 in yeast
Siavash K. Kurdistani, Daniel Robyr, Saeed Tavazoie and Michael Grunstein Nature Genetics31, 248–254
(July 2002); doi:10.1038/ng907
| Abstract | Full Text (HTML/PDF) |
June
letter Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
Rong-guang Zhang, Terina Pappas, Jennifer L. Brace, Paula C. Miller, Tim Oulmassov, John M. Molyneaux, John C. Anderson, James K. Bashkin, Stephen C. Winans and Andrzej Joachimiak Nature417, 971–974
(27 June 2002); doi:10.1038/nature00833
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letter Structural basis for the recognition of hydroxyproline in HIF-1a by pVHL
Wai-Ching Hon, Michael I. Wilson, Karl Harlos, Timothy D. W. Claridge, Christopher J. Schofield, Christopher W. Pugh, Patrick H. Maxwell, Peter J. Ratcliffe, David I. Stuart and E. Yvonne Jones Nature417, 975–978
(27 June 2002); doi:10.1038/nature00767
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review article The unfolded protein response in nutrient sensing and differentiation
Randal J. Kaufman, Donalyn Scheuner, Martin Schröder, Xiaohua Shen, Kyungho Lee, Chuan Yin Liu and Stacey M. Arnold Nature Reviews Molecular Cell Biology3, 411–421
(June 2002); doi:10.1038/nrm829
| Abstract | Full Text (HTML/PDF) |
review article Induction of the neural crest: a multigene process
Anne K. Knecht and Marianne Bronner-Fraser Nature Reviews Genetics3, 453–461
(June 2002); doi:10.1038/nrg819
| Abstract | Full Text (HTML/PDF) |
article Calcium-calmodulin-dependent protein kinase IV is required for fear memory
Feng Wei, Chang-Shen Qiu, Jason Liauw, Daphné A. Robinson, Nga Ho, Talal Chatila and Min Zhuo Nature Neuroscience5, 573–579
(June 2002); doi:10.1038/nn855
| Abstract | Full Text (HTML/PDF) |
letters to nature T-box gene tbx5 is essential for formation of the pectoral limb bud
Dae-Gwon Ahn, Matthew J. Kourakis, Laurel A. Rohde, Lee M. Silver and Robert K. Ho Nature417, 754–758
(13 June 2002); doi:10.1038/nature00814
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letter Tbx24, encoding a T-box protein, is mutated in the zebrafish somite-segmentation mutant fused somites
Masataka Nikaido, Atsushi Kawakami, Atsushi Sawada, Makoto Furutani-Seiki, Hiroyuki Takeda and Kazuo Araki Nature Genetics31, 195–199
(June 2002); doi:10.1038/ng899
| First Paragraph | Full Text (HTML/PDF) |
perspectives Timeline: Fortuitous convergences: the beginnings of JUN
Peter K. Vogt Nature Reviews Cancer2, 465–469
(June 2002); doi:10.1038/nrc818
| Abstract | Full Text (HTML/PDF) |
May
letters to nature Transcription coactivator TRAP220 is required for PPARg2-stimulated adipogenesis
Kai Ge, Mohamed Guermah, Chao-Xing Yuan, Mitsuhiro Ito, Annika E. Wallberg, Bruce M. Spiegelman and Robert G. Roeder Nature 417, 563–567
(May 2002); doi:10.1038/417563a
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research article Reprogramming fibroblasts to express T-cell functions using cell extracts
Anne-Mari Hĺkelien, Helga B. Landsverk, James M. Robl, Bjřrn S. Skĺlhegg and Philippe Collas Nature Biotechnology20, 460–466
(May 2002); doi:10.1038/nbt0502-460
| Abstract | Full Text (HTML/PDF) |
letter Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signaling during mouse development
Karen Niederreither, Suzan Abu-Abed, Brigitte Schuhbaur, Martin Petkovich, Pierre Chambon and Pascal Dollé Nature Genetics31, 84–88
(May 2002); doi:10.1038/ng876
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news and views Retinoid metabolism: a balancing act
Thomas Perlmann Nature Genetics31, 7–9
(May 2002); doi:10.1038/ng877
| Full Text (HTML/PDF) |
article Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis
Paul D. Gottlieb, Stephanie A. Pierce, Robert J. Sims III, Hiroyuki Yamagishi, Elizabeth K. Weihe, June V. Harriss, Shanna D. Maika, William A. Kuziel, Heather L. King, Eric N. Olson, Osamu Nakagawa and Deepak Srivastava Nature Genetics31, 25–32
(May 2002); doi:10.1038/ng866
| Abstract | Full Text (HTML/PDF) |
news and views CREB family transcription factors inhibit neuronal suicide
Ted M. Dawson and David D. Ginty Nature Medicine8, 450–451
(May 2002); doi:10.1038/nm0502-450
| Full Text (HTML/PDF) |
article Disruption of CREB function in brain leads to neurodegeneration
Theo Mantamadiotis, Thomas Lemberger, Susanne C. Bleckmann, Heidrun Kern, Oliver Kretz, Ana Martin Villalba, François Tronche, Christoph Kellendonk, Daniel Gau, Josef Kapfhammer, Christiane Otto, Wolfgang Schmid and Günther Schütz Nature Genetics31, 47–54
(May 2002); doi:10.1038/ng882
| Abstract | Full Text (HTML/PDF) |
review article Gli and hedgehog in cancer: tumours, embryos and stem cells
Ariel Ruiz i Altaba, Pilar Sánchez and Nadia Dahmane Nature Reviews Cancer2, 361–372
(May 2002); doi:10.1038/nrc796
| Abstract | Full Text (HTML/PDF) |
April
article CREB required for the stability of new and reactivated fear memories
Satoshi Kida, Sheena A. Josselyn, Sandra Peńa de Ortiz, Jeffrey H. Kogan, Itzamarie Chevere, Shoichi Masushige and Alcino J. Silva Nature Neuroscience5, 348–355
(April 2002); doi:10.1038/nn819
| Abstract | Full Text (HTML/PDF) |
letter Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus
Seung K. Kim, Licia Selleri, Joon S. Lee, Andrew Y. Zhang, Xueying Gu, Yakop Jacobs and Michael L. Cleary Nature Genetics30, 430–435
(April 2002); doi:10.1038/ng860
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article TLR4, but not TLR2, mediates IFN-b-induced STAT1a/b-dependent gene expression in macrophages
Vladimir Toshchakov, Bryan W. Jones, Pin-Yu Perera, Karen Thomas, M. Joshua Cody, Shuling Zhang, Bryan R. G. Williams, Jennifer Major, Thomas A. Hamilton, Matthew J. Fenton and Stefanie N. Vogel Nature Immunology3, 392–398
(April 2002); doi:10.1038/ni774
| Abstract | Full Text (HTML/PDF) |
review article NF-kB IN CANCER: FROM INNOCENT BYSTANDER TO MAJOR CULPRIT
Michael Karin, Yixue Cao, Florian R. Greten and Zhi-Wei Li Nature Reviews Cancer2, 301–310
(April 2002); doi:10.1038/nrc780
| Abstract | Full Text (HTML/PDF) |
letters to nature Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays
Finny G. Kuruvilla, Alykhan F. Shamji, Scott M. Sternson, Paul J. Hergenrother and Stuart L. Schreiber Nature 416, 653–657
(April 2002); doi:10.1038/416653a
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letters to nature AP-1 functions upstream of CREB to control synaptic plasticity in Drosophila
Subhabrata Sanyal, David J. Sandstrom, Charles A. Hoeffer and Mani Ramaswami Nature 416, 870–874
(April 2002); doi:10.1038/416870a
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January
article Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
Thomas G. Hofmann, Andreas Möller, Hüseyin Sirma, Hanswalter Zentgraf, Yoichi Taya, Wulf Dröge, Hans Will and M. Lienhard Schmitz Nature Cell Biology4, 1–10
(January 2002); doi:10.1038/ncb715
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article Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
Gabriella D'Orazi, Barbara Cecchinelli, Tiziana Bruno, Isabella Manni, Yuichiro Higashimoto, Shin'ichi Saito, Monica Gostissa, Sabrina Coen, Alessandra Marchetti, Giannino Del Sal, Giulia Piaggio, Maurizio Fanciulli, Ettore Appella and Silvia Soddu Nature Cell Biology4, 11–19
(January 2002); doi:10.1038/ncb714
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review article TRANSCRIPTION: MAPK-REGULATED TRANSCRIPTION: A CONTINUOUSLY VARIABLE GENE SWITCH?
Catherine A. Hazzalin and Louis C. Mahadevan Nature Reviews Molecular Cell Biology3, 30–40
(January 2002); doi:10.1038/nrm715
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news and views Microbiology: Group effort in toxin synthesis
Gary M. Dunny Nature 415, 33–34
(January 2002); doi:10.1038/415033a
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