letter Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin
Toru Hirota, Jesse J. Lipp, Ban-Hock Toh and Jan-Michael Peters Nature438, 1176–1180
(22 December 2005); doi:10.1038/nature04254
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letter Double chromodomains cooperate to recognize the methylated histone H3 tail
John F. Flanagan, Li-Zhi Mi, Maksymilian Chruszcz, Marcin Cymborowski, Katrina L. Clines, Youngchang Kim, Wladek Minor, Fraydoon Rastinejad and Sepideh Khorasanizadeh Nature438, 1181–1185
(22 December 2005); doi:10.1038/nature04290
| First Paragraph | Full Text (HTML / PDF) |
letter Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36
Zhong Zhao, Yu Yu, Denise Meyer, Chengjun Wu and Wen-Hui Shen Nature Cell Biology7, 1256–1260
(December 2005); doi:10.1038/ncb1329
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Review article Oncogenic PI3K deregulates transcription and translation
Andreas G. Bader, Sohye Kang, Li Zhao and Peter K. Vogt Nature Reviews Cancer5, 921–929
(December 2005); doi:10.1038/nrc1753
| Summary | Full Text (HTML / PDF) |
letter Differential role of CENP-A in the segregation of holocentric C. elegans chromosomes during meiosis and mitosis
Joost Monen, Paul S. Maddox, Francie Hyndman, Karen Oegema and Arshad Desai Nature Cell Biology7, 1248–1255
(December 2005); doi:10.1038/ncb1331
| First Paragraph | Full Text (HTML/PDF) |
article The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils
Zhong-Jian Shen, Stephane Esnault and James S Malter Nature Immunology6, 1280–1287
(December 2005); doi:10.1038/ni1266
| Abstract | Full Text (HTML/PDF) |
news and views Pin1: a proline isomerase that makes you wheeze?
Paul Anderson Nature Immunology6, 1211–1212
(December 2005); doi:10.1038/ni1205-1211
| Full Text (HTML/PDF) |
review article A role for Kaiso-p120ctn complexes in cancer?
Frans M. van Roy and Pierre D. McCrea Nature Reviews Cancer5, 956–964
(December 2005); doi:10.1038/nrc1752
| Summary | Full Text (HTML / PDF) |
article Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
Marcin Kortylewski, Maciej Kujawski, Tianhong Wang, Sheng Wei, Shumin Zhang, Shari Pilon-Thomas, Guilian Niu, Heidi Kay, James Mulé, William G Kerr, Richard Jove, Drew Pardoll and Hua Yu Nature Medicine11, 1314–1321
(December 2005); doi:10.1038/nm1325
| Abstract | Full Text (HTML/PDF) |
letter The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
Eran Hornstein, Jennifer H. Mansfield, Soraya Yekta, Jimmy Kuang-Hsien Hu, Brian D. Harfe, Michael T. McManus, Scott Baskerville, David P. Bartel and Clifford J. Tabin Nature438, 671–674
(01 December 2005); doi:10.1038/nature04138
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letter The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression
Andrew S. Turnell, Grant S. Stewart, Roger J. A. Grand, Susan M. Rookes, Ashley Martin, Hiroyuki Yamano, Stephen J. Elledge and Phillip H. Gallimore Nature438, 690–695
(01 December 2005); doi:10.1038/nature04151
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article NMDA receptors regulate developmental gap junction uncoupling via CREB signaling
Harsha Arumugam, Xinhuai Liu, Paul J Colombo, Roderick A Corriveau and Andrei B Belousov Nature Neuroscience8, 1720–1726
(December 2005); doi:10.1038/nn1588
| Abstract | Full Text (HTML/PDF) |
news and views Flipping the switch from electrical to chemical communication
Karl Kandler and Edda Thiels Nature Neuroscience8, 1633–1634
(December 2005); doi:10.1038/nn1205-1633
| Full Text (HTML/PDF) |
November
letter Direct observation of base-pair stepping by RNA polymerase
Elio A. Abbondanzieri, William J. Greenleaf, Joshua W. Shaevitz, Robert Landick and Steven M. Block Nature438, 460–465
(24 November 2005); doi:10.1038/nature04268
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letter Evidence for de novo imprinted X-chromosome inactivation independent of meiotic inactivation in mice
Ikuhiro Okamoto, Danielle Arnaud, Patricia Le Baccon, Arie P. Otte, Christine M. Disteche, Philip Avner and Edith Heard Nature438, 369–373
(17 November 2005); doi:10.1038/nature04155
| First Paragraph | Full Text (HTML / PDF) |
letter Chromatin remodelling at a DNA double-strand break site in Saccharomyces cerevisiae
Toyoko Tsukuda, Alastair B. Fleming, Jac A. Nickoloff and Mary Ann Osley Nature438, 379–383
(17 November 2005); doi:10.1038/nature04148
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article Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
Laurie E Harrington, Robin D Hatton, Paul R Mangan, Henrietta Turner, Theresa L Murphy, Kenneth M Murphy and Casey T Weaver Nature Immunology6, 1123–1132
(November 2005); doi:10.1038/ni1254
| Abstract | Full Text (HTML/PDF) |
article A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
Heon Park, Zhaoxia Li, Xuexian O Yang, Seon Hee Chang, Roza Nurieva, Yi-Hong Wang, Ying Wang, Leroy Hood, Zhou Zhu, Qiang Tian and Chen Dong Nature Immunology6, 1133–1141
(November 2005); doi:10.1038/ni1261
| Abstract | Full Text (HTML/PDF) |
news and views TH-17: a giant step from TH1 and TH2
Thomas A Wynn Nature Immunology6, 1069–1070
(November 2005); doi:10.1038/ni1105-1069
| Full Text (HTML/PDF) |
review article The organization and inheritance of the mitochondrial genome
Xin Jie Chen and Ronald A. Butow Nature Reviews Genetics6, 815–825
(November 2005); doi:10.1038/nrg1708 Nature Reviews Genetics AOP published online
| Summary | Full Text (HTML / PDF) |
article The yeast Pif1p helicase removes telomerase from telomeric DNA
Jean-Baptiste Boulé, Leticia R. Vega and Virginia A. Zakian Nature438, 57–61
(03 November 2005); doi:10.1038/nature04091
| Summary | Full Text (HTML / PDF) |
letter The transcription factor Engrailed-2 guides retinal axons
Isabelle Brunet, Christine Weinl, Michael Piper, Alain Trembleau, Michel Volovitch, William Harris, Alain Prochiantz and Christine Holt Nature438, 94–98
(03 November 2005); doi:10.1038/nature04110
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letter A putative stimulatory role for activator turnover in gene expression
J. Russell Lipford, Geoffrey T. Smith, Yong Chi and Raymond J. Deshaies Nature438, 113–116
(03 November 2005); doi:10.1038/nature04098
| First Paragraph | Full Text (HTML / PDF) |
October
letter The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus
Benjamin Loppin, Emilie Bonnefoy, Caroline Anselme, Anne Laurençon, Timothy L. Karr and Pierre Couble Nature437, 1386–1390
(27 October 2005); doi:10.1038/nature04059
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article BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
Ryan T Phan, Masumichi Saito, Katia Basso, Huifeng Niu and Riccardo Dalla-Favera Nature Immunology6, 1054–1060
(October 2005); doi:10.1038/ni1245
| Abstract | Full Text (HTML/PDF) |
news and views A-Miz-ing BCL6
Xiaosheng Wu and Diane F Jelinek Nature Immunology6, 964–966
(October 2005); doi:10.1038/ni1005-964
| | Full Text (HTML/PDF) |
article The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
Seung-Hoi Koo, Lawrence Flechner, Ling Qi, Xinmin Zhang, Robert A. Screaton, Shawn Jeffries, Susan Hedrick, Wu Xu, Fayçal Boussouar, Paul Brindle, Hiroshi Takemori and Marc Montminy Nature437, 1109–11
(20 October 2005); doi:10.1038/nature03967
| Abstract | Full Text (HTML / PDF) |
review article Regulation of MHC class II gene expression by the class II transactivator
Walter Reith, Salomé LeibundGut-Landmann and Jean-Marc Waldburger Nature Reviews Immunology5, 793–806
(October 2005); doi:10.1038/nri1708
| Abstract | Full Text (HTML / PDF) |
letter A network-based analysis of systemic inflammation in humans
Steve E. Calvano, Wenzhong Xiao, Daniel R. Richards, Ramon M. Felciano, Henry V. Baker, Raymond J. Cho, Richard O. Chen, Bernard H. Brownstein, J. Perren Cobb, S. Kevin Tschoeke, Carol Miller-Graziano, Lyle L. Moldawer, Michael N. Mindrinos, Ronald W. Davis, Ronald G. Tompkins, Stephen F. Lowry and Inflamm and Host Response to Injury Large Scale Collab. Res. Program Nature437, 1032–1037
(13 October 2005); doi:10.1038/nature03985
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letter Retraction: RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription
Vera Schramke, Daniel M. Sheedy, Ahmet M. Denli, Carolina Bonila, Karl Ekwall, Gregory J. Hannon and Robin C. Allshire Nature437, 1057
(13 October 2005); doi:10.1038/nature04181
| Full Text (HTML / PDF) |
article IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
Taro Kawai, Ken Takahashi, Shintaro Sato, Cevayir Coban, Himanshu Kumar, Hiroki Kato, Ken J Ishii, Osamu Takeuchi and Shizuo Akira Nature Immunology6, 981–988
(October 2005); doi:10.1038/ni1243
| Abstract | Full Text (HTML/PDF) |
news and views 'PPAR'ting ways with inflammation
Shannon T Bailey and Sankar Ghosh Nature Immunology6, 966–967
(October 2005); doi:10.1038/ni1005-966
| Full Text (HTML/PDF) |
review article The role of chromatin structure in regulating the expression of clustered genes
Duncan Sproul, Nick Gilbert and Wendy A. Bickmore Nature Reviews Genetics6, 775–781
(October 2005); doi:10.1038/nrg1688
| Abstract | Full Text (HTML / PDF) |
September
letter A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-γ
Gabriel Pascual, Amy L. Fong, Sumito Ogawa, Amir Gamliel, Andrew C. Li, Valentina Perissi, David W. Rose, Timothy M. Willson, Michael G. Rosenfeld and Christopher K. Glass Nature437, 759–763
(29 September 2005); doi:10.1038/nature03988
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letter Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs
Brendan J Frey, Naveed Mohammad, Quaid D Morris, Wen Zhang, Mark D Robinson, Sanie Mnaimneh, Richard Chang, Qun Pan, Eric Sat, Janet Rossant, Benoit G Bruneau, Jane E Aubin, Benjamin J Blencowe and Timothy R Hughes Nature Genetics37, 991–996
(September 2005); doi:10.1038/ng1630
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article Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1
Handan Kaygun and William F Marzluff Nature Structural and Molecular Biology12, 794–800
(September 2005); doi:10.1038/nsmb972
| Abstract | Full Text (HTML/PDF) |
article Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins
Rainer Zenz, Robert Eferl, Lukas Kenner, Lore Florin, Lars Hummerich, Denis Mehic, Harald Scheuch, Peter Angel, Erwin Tschachler and Erwin F. Wagner Nature437, 369–375
(15 September 2005); doi:10.1038/nature03963
| Abstract | Full Text (HTML / PDF) |
letter An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation
Min Gyu Lee, Christopher Wynder, Neil Cooch and Ramin Shiekhattar Nature437, 432–435
(15 September 2005); doi:10.1038/nature04021
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letter LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription
Eric Metzger, Melanie Wissmann, Na Yin, Judith M. Müller, Robert Schneider, Antoine H. F. M. Peters, Thomas Günther, Reinhard Buettner and Roland Schüle Nature437, 436–439
(15 September 2005); doi:10.1038/nature04020
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brief communication Distinct roles of IκB proteins in regulating constitutive NF-kB activity
Vinay Tergaonkar, Ricardo G Correa, Masahito Ikawa and Inder M Verma Nature Cell Biology7, 921–923
(September 2005); doi:10.1038/ncb1296
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letter Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development
Abdolrahman S. Nateri, Bradley Spencer-Dene and Axel Behrens Nature437, 281–285
(08 September 2005); doi:10.1038/nature03914
| First Paragraph | Full Text (HTML / PDF) |
August
article Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling
Brendan J Jenkins, Dianne Grail, Thao Nheu, Meri Najdovska, Bo Wang, Paul Waring, Melissa Inglese, Rachel M McLoughlin, Simon A Jones, Nicholas Topley, Heinz Baumann, Louise M Judd, Andrew S Giraud, Alex Boussioutas, Hong-Jian Zhu and Matthias Ernst Nature Medicine11, 845–852
(August 2005); doi:10.1038/nm1282
| Abstract | Full Text (HTML/PDF) |
letter Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation
Angela H Ting, Kornel E Schuebel, James G Herman and Stephen B Baylin Nature Genetics37, 906–910
(August 2005); doi:10.1038/ng1611
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article Real-time imaging of ligand-induced IKK activation in intact cells and in living mice
Shimon Gross and David Piwnica-Worms Nature Methods2, 607–614
(August 2005); doi:10.1038/nmeth779
| Abstract | Full Text (HTML/PDF) |
review article Transcriptional regulation and transformation by Myc proteins
Sovana Adhikary and Martin Eilers Nature Reviews Molecular Cell Biology6, 635–645
(August 2005); doi:10.1038/nrm1703
| Summary | Full Text (HTML / PDF) |
review article Regulation of gene-activation pathways by PIAS proteins in the immune system
Ke Shuai and Bin Liu Nature Reviews Immunology5, 593–605
(August 2005); doi:10.1038/nri1667
| Summary | Full Text (HTML / PDF) |
letter ERM is required for transcriptional control of the spermatogonial stem cell niche
Chen Chen, Wenjun Ouyang, Vadim Grigura, Qing Zhou, Kay Carnes, Hyunjung Lim, Guang-Quan Zhao, Silvia Arber, Natasza Kurpios, Theresa L. Murphy, Alec M. Cheng, John A. Hassell, Varadaraj Chandrashekar, Marie-Claude Hofmann, Rex A. Hess and Kenneth M. Murphy Nature436, 1030–1034
(18 August 2005); doi:10.1038/nature03894
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letter Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis
Rebecca A. Wingert, Jenna L. Galloway, Bruce Barut, Helen Foott, Paula Fraenkel, Jennifer L. Axe, Gerhard J. Weber, Kimberly Dooley, Alan J. Davidson, Bettina Schmidt, Barry H. Paw, George C. Shaw, Paul Kingsley, James Palis, Heidi Schubert, Opal Chen, Jerry Kaplan, The Tübingen 2000 Screen Consortium and Leonard I. Zon Nature436, 1035–1039
(18 August 2005); doi:10.1038/nature03887
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letter Conditional telomerase induction causes proliferation of hair follicle stem cells
Kavita Y. Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I. Tennen, Estee Wang, Maja K. Artandi, Anthony E. Oro and Steven E. Artandi Nature436, 1048–1052
(18 August 2005); doi:10.1038/nature03836
| First Paragraph | Full Text (HTML / PDF) |
news and views Cell biology: Shaggy mouse tales
Elizabeth H. Blackburn Nature436, 922–923
(18 August 2005); doi:10.1038/436922a
| Full Text (HTML / PDF) |
letter A high-resolution map of active promoters in the human genome
Tae Hoon Kim, Leah O. Barrera, Ming Zheng, Chunxu Qu, Michael A. Singer, Todd A. Richmond, Yingnian Wu, Roland D. Green and Bing Ren Nature436, 876–880
(11 August 2005); doi:10.1038/nature03877
| First Paragraph | Full Text (HTML / PDF) |
letter Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin
Julia E. Kravchenko, Igor B. Rogozin, Eugene V. Koonin and Peter M. Chumakov Nature436, 735–739
(04 August 2005); doi:10.1038/nature03848
| First Paragraph | Full Text (HTML / PDF) |
letter TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
Thimmaiah P. Chendrimada, Richard I. Gregory, Easwari Kumaraswamy , Jessica Norman, Neil Cooch, Kazuko Nishikura and Ramin Shiekhattar Nature436, 740–744
(04 August 2005); doi:10.1038/nature03868
| First Paragraph | Full Text (HTML / PDF) |
July
letter MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
Jidong Liu, Marco Antonio Valencia-Sanchez, Gregory J. Hannon and Roy Parker Nature Cell Biology7, 719–723
(July 2005); doi:10.1038/ncb1274
| First Paragraph | Full Text (HTML/PDF) |
news and views RNAi and the P-body connection
John J. Rossi Nature Cell Biology7, 643–644
(July 2005); doi:10.1038/ncb0705-643
| Full Text (HTML/PDF) |
article Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice
Daniela Foti, Eusebio Chiefari, Monica Fedele, Rodolfo Iuliano, Leonardo Brunetti, Francesco Paonessa, Guidalberto Manfioletti, Fabrizio Barbetti, Arturo Brunetti, Carlo M Croce, Alfredo Fusco and Antonio Brunetti Nature Medicine11, 765–773
(July 2005); doi:10.1038/nm1254
| Abstract | Full Text (HTML/PDF) |
letter DNA processing is not
required for ATM-mediated telomere damage response after TRF2
deletion Giulia B. Celli and Titia de Lange Nature Cell Biology7, 712–718 (July 2005); doi:10.1038/ncb1275 | First Paragraph | Full Text (HTML/PDF)
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article Inhibitors of
γ-secretase block in vivo and in vitro T helper type 1
polarization by preventing Notch upregulation of Tbx21 Lisa M
Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G
Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer, Lisa
Kostura, Abdul H Fauq, Katherine Simpson, Kimberly A Such, Lucio Miele, Todd E
Golde, Stephen D Miller and Barbara A Osborne Nature Immunology6, 680–688 (July 2005); doi:10.1038/ni1209 | Abstract | Full Text (HTML/PDF)
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news and views Notch in
lymphopoiesis and T cell polarization Harald von Boehmer Nature
Immunology6, 641–642 (July 2005); doi:10.1038/ni0705-641 | Full Text
(HTML/PDF) |
review article Controlling nuclear receptors: the circular logic of cofactor cycles
Valentina Perissi and Michael G. Rosenfeld Nature Reviews Molecular Cell Biology6, 542–554
(July 2005); doi:10.1038/nrm1680
| Summary | Full Text (HTML / PDF) |
June
letter RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription
Vera Schramke, Daniel M. Sheedy, Ahmet M. Denli, Carolina Bonila, Karl Ekwall, Gregory J. Hannon and Robin C. Allshire Nature435, 1275–1279
(30 June 2005); doi:10.1038/nature03652
| First Paragraph | Full Text (HTML/PDF) |
news and views Gene regulation: Expression and silencing coupled
Stephen Buratowski and Danesh Moazed Nature435, 1174–1175
(30 June 2005); doi:10.1038/4351174b
| Full Text (HTML / PDF) |
letter Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
George L. Sen and Helen M. Blau Nature Cell Biology7, 633–636
(June 2005); doi:10.1038/ncb1265
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article Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
Roberto Chiarle, William J Simmons, Honjying Cai, Girish Dhall, Alberto Zamo, Regina Raz, James G Karras, David E Levy and Giorgio Inghirami Nature Medicine11, 623–629
(June 2005); doi:10.1038/nm1249
| Abstract | Full Text (HTML/PDF) |
news and views Validating Stat3 in cancer therapy
James E Darnell Jr Nature Medicine11, 595–596
(June 2005); doi:10.1038/nm0605-595
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article Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation
Fan Pan, Anthony R Means and Jun O Liu The EMBO Journal24, 2104–2113
(June 2005); doi:10.1038/sj.emboj.7600685
| Abstract | Full Text (HTML/PDF) |
letter Stem cell division is regulated by the microRNA pathway S. D. Hatfield, H. R. Shcherbata, K. A. Fischer, K. Nakahara, R. W. Carthew and H. Ruohola-Baker Nature435, 974–978
(16 June 2005); doi:10.1038/nature03816
| First Paragraph | Full Text (HTML / PDF) |
letter Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis
Helena Jonsson, Paul Allen and Stanford L Peng Nature Medicine11, 666–671
(June 2005); doi:10.1038/nm1248
| First Paragraph | Full Text (HTML/PDF) |
news and views A fork in the pathway to inflammation and arthritis
Foo Y Liew and Iain B McInnes Nature Medicine11, 601–602
(June 2005); doi:10.1038/nm0605-601
| Full Text (HTML/PDF) |
article LINGO-1 negatively regulates myelination by oligodendrocytes
Sha Mi, Robert H Miller, Xinhua Lee, Martin L Scott, Svetlane Shulag-Morskaya, Zhaohui Shao, Jufang Chang, Greg Thill, Melissa Levesque, Mingdi Zhang, Cathy Hession, Dinah Sah, Bruce Trapp, Zhigang He, Vincent Jung, John M McCoy and R Blake Pepinsky Nature Neuroscience8, 745–751
(June 2005); doi:10.1038/nn1460
| Abstract | Full Text (HTML/PDF) |
article A newly discovered function for RNase L in regulating translation termination
Florence Le Roy, Tamim Salehzada, Catherine Bisbal, Joseph P Dougherty and Stuart W Peltz Nature Structural and Molecular Biology12, 505–512
(June 2005); doi:10.1038/nsmb944
| Abstract | Full Text (HTML/PDF) |
news and views The end justifies the means
Allan Jacobson Nature Structural and Molecular Biology12, 474–475
(June 2005); doi:10.1038/nsmb0605-474
| Full Text (HTML/PDF) |
letter A microRNA polycistron as a potential human oncogene
Lin He, J. Michael Thomson, Michael T. Hemann, Eva Hernando-Monge, David Mu, Summer Goodson, Scott Powers, Carlos Cordon-Cardo, Scott W. Lowe, Gregory J. Hannon and Scott M. Hammond Nature435, 828–833
(09 June 2005); doi:10.1038/nature03552
| First Paragraph | Full Text (HTML / PDF) |
letter c-Myc-regulated microRNAs modulate E2F1 expression
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang and Joshua T. Mendell Nature435, 839–843
(09 June 2005); doi:10.1038/nature03677
| First Paragraph | Full Text (HTML / PDF) |
news and views Cancer genomics: Small RNAs with big impacts
Paul S. Meltzer Nature435, 745–746
(09 June 2005); doi:10.1038/435745a
| Full Text (HTML / PDF) |
article Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin
Yu-Hua Tseng, Atul J. Butte, Efi Kokkotou, Vijay K. Yechoor, Cullen M. Taniguchi, Kristina M. Kriauciunas, Aaron M. Cypess, Michio Niinobe, Kazuaki Yoshikawa, Mary Elizabeth Patti and C. Ronald Kahn Nature Cell Biology7, 601–611
(June 2005); doi:10.1038/ncb1259
| Abstract | Full Text (HTML/PDF) |
news and views Fickle factor foils fat fate
Ormond A. MacDougald and Charles F. Burant Nature Cell Biology7, 543–545
(June 2005); doi:10.1038/ncb0605-543
| Full Text (HTML/PDF) |
research article Systemic Agrobacterium tumefaciens-mediated transfection of viral replicons for efficient transient expression in plants
Sylvestre Marillonnet, Carola Thoeringer, Romy Kandzia, Victor Klimyuk and Yuri Gleba Nature Biotechnology23, 718–723
(June 2005); doi:10.1038/nbt1094
| Abstract | Full Text (HTML/PDF) |
news and views Viral-mediated plant transformation gets a boost
Stanton B Gelvin Nature Biotechnology23, 684–685
(June 2005); doi:10.1038/nbt0605-684
| Full Text (HTML/PDF) |
review article Control of lymphocyte development by nuclear factor-κB
Ulrich Siebenlist, Keith Brown and Estefania Claudio Nature Reviews Immunology5, 435–445
(June 2005); doi:10.1038/nri1629
| Summary | Full Text (HTML / PDF) |
analysis Mining for regulatory programs in the cancer transcriptome
Daniel R Rhodes, Shanker Kalyana-Sundaram, Vasudeva Mahavisno, Terrence R Barrette, Debashis Ghosh and Arul M Chinnaiyan Nature Genetics37, 579–583
(June 2005); doi:10.1038/ng1578
| Abstract | Full Text (HTML/PDF) |
article SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability
Narendrakumar Ramanan, Ying Shen, Sarah Sarsfield, Thomas Lemberger, Günther Schütz, David J Linden and David D Ginty Nature Neuroscience8, 759–767
(June 2005); doi:10.1038/nn1462
| Abstract | Full Text (HTML/PDF) |
article The RISC subunit Tudor-SN binds to hyper-edited double-stranded RNA and promotes its cleavage
A D J Scadden Nature Structural and Molecular Biology12, 489–496
(June 2005); doi:10.1038/nsmb936
| Abstract | Full Text (HTML/PDF) |
review article Process or perish: quality control in mRNA biogenesis
Milo B Fasken and Anita H Corbett Nature Structural and Molecular Biology12, 482–488
(June 2005); doi:10.1038/nsmb945
| Abstract | Full Text (HTML/PDF) |
May
article The F-box protein TIR1 is an auxin receptor
Nihal Dharmasiri, Sunethra Dharmasiri and Mark Estelle Nature435, 441–445
(26 May 2005); doi:10.1038/nature03543
| Summary | Full Text (HTML / PDF) |
article The Arabidopsis F-box protein TIR1 is an auxin receptor
Stefan Kepinski and Ottoline Leyser Nature435, 446–451
(26 May 2005); doi:10.1038/nature03542
| Summary | Full Text (HTML / PDF) |
news and views Plant biology: Auxin action
Judy Callis Nature435, 436–437
(26 May 2005); doi:10.1038/435436b
| Full Text (HTML / PDF) |
article Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
Wenjun Cheng, Jinsong Liu, Hiroyuki Yoshida, Daniel Rosen and Honami Naora Nature Medicine11, 531–537
(May 2005); doi:10.1038/nm1230
| Abstract | Full Text (HTML/PDF) |
review article The RUNX genes: gain or loss of function in cancer
Karen Blyth, Ewan R. Cameron and James C. Neil Nature Reviews Cancer5, 376–387
(2005) doi:10.1038/nrc1607
| Summary | Full Text (HTML / PDF) |
letter The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity
Mitsuru Morimoto, Yu Takahashi, Maho Endo and Yumiko Saga Nature435, 354–359
(19 May 2005); doi:10.1038/nature03591
| First Paragraph | Full Text (HTML / PDF) |
article Retinoic acid signalling links left-right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo
Yasuhiko Kawakami, Ángel Raya, R. Marina Raya, Concepción Rodríguez-Esteban and Juan Carlos Izpisúa Belmonte Nature435, 165–171
(12 May 2005); doi:10.1038/nature03512
| Summary | Full Text (HTML / PDF) |
news and views Developmental biology: Asymmetrical threat averted
Eran Hornstein and Clifford J. Tabin Nature435, 155–156
(12 May 2005); doi:10.1038/435155a
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article FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination
Yosuke Tanaka, Yasushi Okada and Nobutaka Hirokawa Nature435, 172–177
(12 May 2005); doi:10.1038/nature03494
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letters to nature Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos
Julien Vermot and Olivier Pourquié ′Nature435, 215–220
(12 May 2005); doi:10.1038/nature03488
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article Epistasis analysis with global transcriptional phenotypes
Nancy Van Driessche, Janez Demsar, Ezgi O Booth, Paul Hill, Peter Juvan, Blaz Zupan, Adam Kuspa and Gad Shaulsky Nature Genetics37, 471–477
(May 2005); doi:10.1038/ng1545
| Abstract | Full Text (HTML/PDF) |
news and views Universal epistasis analysis
Timothy R Hughes Nature Genetics37, 457–458
(May 2005); doi:10.1038/ng0505-457
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letters to nature Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
Li-Ru You, Fu-Jung Lin, Christopher T. Lee, Francesco J. DeMayo, Ming-Jer Tsai and Sophia Y. Tsai Nature435, 98–104
(05 May 2005); doi:10.1038/nature03511
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news and views IRF-7 triggers the interferon alarm
Myrto Raftopoulou
Nature Cell Biology7, 459
(May 2005); doi:10.1038/ncb0505-459
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review article Interactions of NF-κB with chromatin: the art of being at the right place at the right time
Gioacchino Natoli, Simona Saccani, Daniela Bosisio and Ivan Marazzi Nature Immunology6, 439–445
(May 2005); doi:10.1038/ni1196
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article A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis
Fei He, Weihong Ge, Keri Martinowich, Sara Becker-Catania, Volkan Coskun, Wenyu Zhu, Hao Wu, Diogo Castro, Francois Guillemot, Guoping Fan, Jean de Vellis and Yi E Sun Nature Neuroscience8, 616–625
(May 2005); doi:10.1038/nn1440
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article Independence and reproducibility across microarray platforms
Jennie E Larkin, Bryan C Frank, Haralambos Gavras, Razvan Sultana and John Quackenbush
Nature Methods2, 337–344
(May 2005); doi:10.1038/nmeth757
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article Multiple-laboratory comparison of microarray platforms
Rafael A Irizarry, Daniel Warren, Forrest Spencer, Irene F Kim, Shyam Biswal, Bryan C Frank, Edward Gabrielson, Joe G N Garcia, Joel Geoghegan, Gregory Germino, Constance Griffin, Sara C Hilmer, Eric Hoffman, Anne E Jedlicka, Ernest Kawasaki, Francisco Martínez-Murillo, Laura Morsberger, Hannah Lee, David Petersen, John Quackenbush, Alan Scott, Michael Wilson, Yanqin Yang, Shui Qing Ye and Wayne Yu
Nature Methods2, 345–350
(May 2005); doi:10.1038/nmeth756
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article Standardizing global gene expression analysis between laboratories and across platforms
Members of the Toxicogenomics Research Consortium: B.K. Weis Nature Methods2, 351–356
(May 2005); doi:10.1038/nmeth754
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news and views Of fish and chips
Gavin Sherlock Nature Methods2, 329–330
(May 2005); doi:10.1038/nmeth0505-329
| Abstract | Full Text (HTML/PDF) |
April
review article Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
Shimon Sakaguchi Nature Immunology6, 345–352
(April 2005); doi:10.1038/ni1178
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letter Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
Susana Gonzalo, Marta García-Cao, Mario F. Fraga, Gunnar Schotta, Antoine H.F.M. Peters, Shane E. Cotter, Raúl Eguía, Douglas C. Dean, Manel Esteller, Thomas Jenuwein and María A. Blasco Nature Cell Biology7, 420–428
(April 2005); doi:10.1038/ncb1235
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article The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
Guangping Sun, Xiaolong Liu, Peter Mercado, S Rhiannon Jenkinson, Magdalini Kypriotou, Lionel Feigenbaum, Philippe Galéra and Rémy Bosselut Nature Immunology6, 373–381
(April 2005); doi:10.1038/ni1183
| Abstract | Full Text (HTML/PDF) |
news and views Switching sides: transcriptional control of CD4 thymocyte lineage commitment
Rose Zamoyska Nature Immunology6, 363–364
(April 2005); doi:10.1038/ni0405-363
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news and views Staufen does double duty
Erika L Meyer and Elizabeth R Gavis Nature Structural and Molecular Biology12, 291–292
(April 2005); doi:10.1038/nsmb0405-291
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letters to nature Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes
Jung Hwa Kim, Bogyou Kim, Ling Cai, Hee June Choi, Kenneth A. Ohgi, Chris Tran, Charlie Chen, Chin Ha Chung, Otmar Huber, David W. Rose, Charles L. Sawyers, Michael G. Rosenfeld and Sung Hee Baek Nature434, 921–926
(14 April 2005); doi:10.1038/nature03452
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letter Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition
Kathrine Abell, Antonio Bilancio, Richard W. E. Clarkson, Paul G. Tiffen, Anton I. Altaparmakov, Thomas G. Burdon, Tomoichiro Asano, Bart Vanhaesebroeck and Christine J. Watson Nature Cell Biology7, 392–398
(April 2005); doi:10.1038/ncb1242
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review article Mechanisms of suppression by suppressor T cells
Harald von Boehmer Nature Immunology6, 338–344
(April 2005); doi:10.1038/ni1180
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review article High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
Michael T. Lotze and Kevin J. Tracey Nature Reviews Immunology5, 331–342
(April 2005); doi:10.1038/nri1594
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article Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities
Beth A Firulli, Dayana Krawchuk, Victoria E Centonze, Neil Vargesson, David M Virshup, Simon J Conway, Peter Cserjesi, Ed Laufer and Anthony B Firulli Nature Genetics37, 373–381
(April 2005); doi:10.1038/ng1525
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article β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
Danette L Daniels and William I Weis Nature Structural and Molecular Biology12, 364–371
(April 2005); doi:10.1038/nsmb912
| Abstract | Full Text (HTML/PDF) |
letters to nature IRF-7 is the master regulator of type-I interferon-dependent immune responses
Kenya Honda, Hideyuki Yanai, Hideo Negishi, Masataka Asagiri, Mitsuharu Sato, Tatsuaki Mizutani, Naoya Shimada, Yusuke Ohba, Akinori Takaoka, Nobuaki Yoshida and Tadatsugu Taniguchi Nature434, 772–777
(07 April 2005); doi:10.1038/nature03464
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review article A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
Jason D Fontenot and Alexander Y Rudensky Nature Immunology6, 331–337
(April 2005); doi:10.1038/ni1179
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article Purified Argonaute2 and an siRNA form recombinant human RISC
Fabiola V Rivas, Niraj H Tolia, Ji-Joon Song, Juan P Aragon, Jidong Liu, Gregory J Hannon and Leemor Joshua-Tor Nature Structural and Molecular Biology12, 340–349
(April 2005); doi:10.1038/nsmb918
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article Identification of microRNAs of the herpesvirus family
Sébastien Pfeffer, Alain Sewer, Mariana Lagos-Quintana, Robert Sheridan, Chris Sander, Friedrich A Grässer, Linda F van Dyk, C Kiong Ho, Stewart Shuman, Minchen Chien, James J Russo, Jingyue Ju, Glenn Randall, Brett D Lindenbach, Charles M Rice, Viviana Simon, David D Ho, Mihaela Zavolan and Thomas Tuschl Nature Methods2, 269–276
(April 2005); doi:10.1038/nmeth746
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news and views Herpesviruses throw a curve ball: new insights into microRNA biogenesis and evolution
Joel R Neilson & Phillip A Sharp Nature Methods2, 252–254
(April 2005); doi:10.1038/nmeth0405-252
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letters to nature Structural insights into mRNA recognition from a PIWI domain-siRNA guide complex
James S. Parker, S. Mark Roe and David Barford Nature434, 663–666
(31 March 2005); doi:10.1038/nature03462
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letters to nature Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein
Jin-Biao Ma, Yu-Ren Yuan, Gunter Meister, Yi Pei, Thomas Tuschl and Dinshaw J. Patel Nature434, 666–670
(31 March 2005); doi:10.1038/nature03514
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review article Thinking quantitatively about transcriptional regulation
Sandra J. Greive and Peter H. von Hippel Nature Reviews Molecular Cell Biology6, 221–232
(March 2005); doi:10.1038/nrm1588
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review article Induction and suppression of RNA silencing: insights from viral infections
Olivier Voinnet Nature Reviews Genetics6, 206–220
(March 2005); doi:10.1038/nrg1555
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news and views RecA kicks Pol V into gear
Joann B Sweasy Nature Structural and Molecular Biology12, 215–216
(March 2005); doi:10.1038/nsmb0305-215
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March
letters to nature Leptin regulation of bone resorption by the sympathetic nervous system and CART
Florent Elefteriou , Jong Deok Ahn, Shu Takeda , Michael Starbuck, Xiangli Yang, Xiuyun Liu, Hisataka Kondo, William G. Richards, Tony W. Bannon, Masaki Noda, Karine Clement, Christian Vaisse and Gerard Karsenty Nature434, 514–520
(24 March 2005); doi:10.1038/nature03398
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news and views Physiology: Do neural signals remodel bone?
Joel K. Elmquist and Gordon J. Strewler Nature434, 447–448
(24 March 2005); doi:10.1038/434447a
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letters to nature Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1
Jérôme Déjardin, Aurélien Rappailles, Olivier Cuvier, Charlotte Grimaud, Martine Decoville, Daniel Locker and Giacomo Cavalli Nature434, 533–538
(24 March 2005); doi:10.1038/nature03386
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article G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes
Mutsuo Harada, Yingjie Qin, Hiroyuki Takano, Tohru Minamino, Yunzeng Zou, Haruhiro Toko, Masashi Ohtsuka, Katsuhisa Matsuura, Masanori Sano, Jun-ichiro Nishi, Koji Iwanaga, Hiroshi Akazawa, Takeshige Kunieda, Weidong Zhu, Hiroshi Hasegawa, Keita Kunisada, Toshio Nagai, Haruaki Nakaya, Keiko Yamauchi-Takihara and Issei Komuro Nature Medicine11, 305–311
(March 2005); doi:10.1038/nm1199
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article Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
Alexander J Muller, James B DuHadaway, P Scott Donover, Erika Sutanto-Ward and George C Prendergast Nature Medicine11, 312–319
(March 2005); doi:10.1038/nm1196
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article Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing
Harikrishnan K N, Maggie Z Chow, Emma K Baker, Sharmistha Pal, Sahar Bassal, Daniella Brasacchio, Li Wang, Jeff M Craig, Peter L Jones, Saïd Sif and Assam El-Osta Nature Genetics37, 254–264
(March 2005); doi:10.1038/ng1516
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news and views SWItching off methylated DNA
Paul A Wade Nature Genetics37, 212–213
(March 2005); doi:10.1038/ng0305-212
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article Directed differentiation of telencephalic precursors from embryonic stem cells
Kiichi Watanabe, Daisuke Kamiya, Ayaka Nishiyama, Tomoko Katayama, Satoshi Nozaki, Hiroshi Kawasaki, Yasuyoshi Watanabe, Kenji Mizuseki and Yoshiki Sasai Nature Neuroscience8, 288–296
(March 2005); doi:10.1038/nn1402
| Abstract | Full Text (HTML/PDF) |
letter Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
Savraj S. Grewal, Ling Li, Amir Orian, Robert N. Eisenman and Bruce A. Edgar Nature Cell Biology7, 295–302
(March 2005); doi:10.1038/ncb1223
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letter c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription
Azadeh Arabi, Siqin Wu, Karin Ridderstråle, Holger Bierhoff, Chiounan Shiue, Karoly Fatyol, Sara Fahlén, Per Hydbring, Ola Söderberg, Ingrid Grummt, Lars-Gunnar Larsson and Anthony P. H. Wright Nature Cell Biology7, 303–310
(March 2005); doi:10.1038/ncb1225
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letter c-Myc binds to human ribosomal DNA and stimulates transcription of rRNA genes by RNA polymerase I
Carla Grandori, Natividad Gomez-Roman, Zoe A. Felton-Edkins, Celine Ngouenet, Denise A. Galloway, Robert N. Eisenman and Robert J. White Nature Cell Biology7, 311–318
(March 2005); doi:10.1038/ncb1224
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news and views The Myc trilogy: lord of RNA polymerases
Thordur Oskarsson and Andreas Trumpp Nature Cell Biology7, 215–217
(March 2005); doi:10.1038/ncb0305-215
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review article Regulation of plasma-cell development
Miriam Shapiro-Shelef and Kathryn Calame Nature Reviews Immunology5, 230–242
(March 2005); doi:10.1038/nri1572
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article Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression
Alexandre Méjat, Francis Ramond, Rhonda Bassel-Duby, Saadi Khochbin, Eric N Olson and Laurent Schaeffer Nature Neuroscience8, 313–321
(March 2005); doi:10.1038/nn1408
| Abstract | Full Text (HTML/PDF) |
research article Programmable ligand-controlled riboregulators of eukaryotic gene expression
Travis S Bayer and Christina D Smolke Nature Biotechnology23, 337–343
(March 2005); doi:10.1038/nbt1069
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news and views Plug-and-play with RNA
Farren J Isaacs and James J Collins Nature Biotechnology23, 306–307
(March 2005); doi:10.1038/nbt0305-306
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letters to nature Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
Akinori Takaoka, Hideyuki Yanai, Seiji Kondo, Gordon Duncan, Hideo Negishi, Tatsuaki Mizutani, Shin-ichi Kano, Kenya Honda, Yusuke Ohba, Tak W. Mak and Tadatsugu Taniguchi Nature434, 243–249
(10 March 2005); doi:10.1038/nature03308
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article STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression
Ferenc A Scheeren, Marianne Naspetti, Sean Diehl, Remko Schotte, Maho Nagasawa, Erwin Wijnands, Ramon Gimeno, Florry A Vyth-Dreese, Bianca Blom and Hergen Spits Nature Immunology6, 303–313
(March 2005); doi:10.1038/ni1172
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article Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
Leonid Bystrykh, Ellen Weersing, Bert Dontje, Sue Sutton, Mathew T Pletcher, Tim Wiltshire, Andrew I Su, Edo Vellenga, Jintao Wang, Kenneth F Manly, Lu Lu, Elissa J Chesler, Rudi Alberts, Ritsert C Jansen, Robert W Williams, Michael P Cooke and Gerald de Haan Nature Genetics37, 225–232
(March 2005); doi:10.1038/ng1497
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news and views Mapping expression in randomized rodent genomes
Karl W Broman Nature Genetics37, 209–210
(March 2005); doi:10.1038/ng0305-209
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letters to nature Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
Joseph T. Rodgers, Carlos Lerin, Wilhelm Haas, Steven P. Gygi, Bruce M. Spiegelman and Pere Puigserver Nature434, 113–118
(03 March 2005); doi:10.1038/nature03354
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review article Intrinsically unstructured proteins and their functions
H. Jane Dyson and Peter E. Wright Nature Reviews Molecular Cell Biology6, 197–208
(March 2005); doi:10.1038/nrm1589
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article Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
Veit Hornung, Margit Guenthner-Biller, Carole Bourquin, Andrea Ablasser, Martin Schlee, Satoshi Uematsu, Anne Noronha, Muthiah Manoharan, Shizuo Akira, Antonin de Fougerolles, Stefan Endres and Gunther Hartmann Nature Medicine11, 263–270
(March 2005); doi:10.1038/nm1191
| Abstract | Full Text (HTML/PDF) |
news and views Sensing the danger in RNA
Marjorie A Robbins and John J Rossi Nature Medicine11, 250–251
(March 2005); doi:10.1038/nm0305-250
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article Actin and hnRNP U cooperate for productive transcription by RNA polymerase II
Alexander Kukalev, Ylva Nord, Carina Palmberg, Tomas Bergman and Piergiorgio Percipalle Nature Structural and Molecular Biology12, 238–244
(March 2005); doi:10.1038/nsmb904
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February
article The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
Xiao He, Xi He, Vibhuti P. Dave, Yi Zhang, Xiang Hua, Emmanuelle Nicolas, Weihong Xu, Bruce A. Roe and Dietmar J. Kappes Nature433, 826–833
(24 February 2005); doi:10.1038/nature03338
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letters to nature Pax3 functions at a nodal point in melanocyte stem cell differentiation
Deborah Lang, Min Min Lu, Li Huang, Kurt A. Engleka, Maozhen Zhang, Emily Y. Chu, Shari Lipner, Arthur Skoultchi, Sarah E. Millar and Jonathan A. Epstein Nature433, 884–887
(24 February 2005); doi:10.1038/nature03292
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letter Synthetic shRNAs as potent RNAi triggers
Despina Siolas, Cara Lerner, Julja Burchard, Wei Ge, Peter S Linsley, Patrick J Paddison, Gregory J Hannon and Michele A Cleary Nature Biotechnology23, 227–231
(February 2005); doi:10.1038/nbt1052
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news and views Immunology: Guide for a cell-fate decision
Ellen A. Robey Nature433, 813–814
(24 February 2005); doi:10.1038/433813a
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letter OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes
Shinichi Kondo, Tomohiko Murakami, Kouko Tatsumi, Maiko Ogata, Soshi Kanemoto, Kumi Otori, Ken Iseki, Akio Wanaka and Kazunori Imaizumi Nature Cell Biology7, 186–194
(February 2005); doi:10.1038/ncb1213
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review article Assembly and function of RNA silencing complexes
Erik J. Sontheimer Nature Reviews Molecular Cell Biology AOP published online 14 January 2005; doi:10.1038/nrm1568
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review article Roles of interferon-regulatory factors in T-helper-cell differentiation
Michael Lohoff and Tak W. Mak Nature Reviews Immunology5, 125–135
(February 2005); doi:10.1038/nri1552
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letter An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas
Paul Roepman, Lodewyk F A Wessels, Nienke Kettelarij, Patrick Kemmeren, Antony J Miles, Philip Lijnzaad, Marcel G J Tilanus, Ronald Koole, Gert-Jan Hordijk, Peter C van der Vliet, Marcel J T Reinders, Piet J Slootweg and Frank C P Holstege Nature Genetics37, 182–186
(February 2005); doi:10.1038/ng1502
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research article Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
Dong-Ho Kim, Mark A Behlke, Scott D Rose, Mi-Sook Chang, Sangdun Choi and John J Rossi Nature Biotechnology23, 222–226
(February 2005); doi:10.1038/nbt1051
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news and views Dicing with siRNA
Bryan R.G. Williams Nature Biotechnology23, 181–182
(February 2005); doi:10.1038/nbt0205-181
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article Localized transfection on arrays of magnetic beads coated with PCR products
Mark Isalan, Maria Isabel Santori, Cayetano Gonzalez and Luis Serrano Nature Methods2, 113–118
(February 2005); doi:10.1038/nmeth732
| Abstract | Full Text (HTML/PDF) |
review article Promoters in the environment: transcriptional regulation in its natural context
Ildefonso Cases and Víctor de Lorenzo Nature Reviews Microbiology3, 105–118
(February 2005); doi:10.1038/nrmicro1084
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letters to nature Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression
Suzanne Carreira, Jane Goodall, Isil Aksan, S. Anna La Rocca, Marie-Dominique Galibert, Laurence Denat, Lionel Larue and Colin R. Goding Nature433, 764–769
(17 February 2005); doi:10.1038/nature03269
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letters to nature Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
Lee P. Lim, Nelson C. Lau, Philip Garrett-Engele, Andrew Grimson, Janell M. Schelter, John Castle, David P. Bartel, Peter S. Linsley and Jason M. Johnson Nature433, 769–773
(17 February 2005); doi:10.1038/nature03315
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research article Biosynthetic labeling of RNA with uracil phosphoribosyltransferase allows cell-specific microarray analysis of mRNA synthesis and decay
Michael D Cleary, Christopher D Meiering, Eric Jan, Rebecca Guymon and John C Boothroyd Nature Biotechnology23, 232–237
(February 2005); doi:10.1038/nbt1061
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news and views A window on the dynamics of biological switches
Michael Bittner Nature Biotechnology23, 183–184
(February 2005); doi:10.1038/nbt0205-183
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review article DNA supercoiling — a global transcriptional regulator for enterobacterial growth?
Andrew Travers and Georgi Muskhelishvili Nature Reviews Microbiology3, 157–169
(February 2005); doi:10.1038/nrmicro1088
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letters to nature The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
Haijuan Yang, Qiubai Li, Jie Fan, William K. Holloman and Nikola P. Pavletich Nature433, 653–657
(10 February 2005); doi:10.1038/nature03234
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news and views Cancer: Catalyst of a catalyst
Stephen C. Kowalczykowski Nature433, 591–592
(10 February 2005); doi:10.1038/433591a
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letters to nature Structural basis for substrate binding, cleavage and allostery in the tRNA maturase RNase Z
Inés Li De La Sierra-Gallay, Olivier Pellegrini and Ciarán Condon Nature433, 657–661
(10 February 2005); doi:10.1038/nature03284
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article FoxM1 is required for execution of the mitotic programme and chromosome stability
Jamila Laoukili, Matthijs R. H. Kooistra, Alexandra Brás, Jos Kauw, Ron M. Kerkhoven, Ashby Morrison, Hans Clevers and René H. Medema Nature Cell Biology7, 126–136
(February 2005); doi:10.1038/ncb1217
| Abstract | Full Text (HTML/PDF) |
news and views FoxM1 dances with mitosis
Robert H. Costa Nature Cell Biology7, 108–110
(February 2005); doi:10.1038/ncb0205-108
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letter p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
Tongxiang Lin, Connie Chao, Shin'ichi Saito, Sharlyn J. Mazur, Maureen E. Murphy, Ettore Appella and Yang Xu Nature Cell Biology7, 165–171
(February 2005); doi:10.1038/ncb1211
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review article Histone variants meet their match
Kavitha Sarma and Danny Reinberg Nature Reviews Molecular Cell Biology6, 139–149
(February 2005); doi:10.1038/nrm1567
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article Accelerated re-epithelialization in β3-integrin-deficient- mice is associated with enhanced TGF-β1 signaling
L E Reynolds, F J Conti, M Lucas, R Grose, S Robinson, M Stone, G Saunders, C Dickson, R O Hynes, A Lacy-Hulbert and K Hodivala-Dilke Nature Medicine11, 167–174
(February 2005); doi:10.1038/nm1165
| Abstract | Full Text (HTML/PDF) |
research article Functional annotation and network reconstruction through cross-platform integration of microarray data
Xianghong Jasmine Zhou, Ming-Chih J Kao, Haiyan Huang, Angela Wong, Juan Nunez-Iglesias, Michael Primig, Oscar M Aparicio, Caleb E Finch, Todd E Morgan and Wing Hung Wong Nature Biotechnology23, 238–243
(February 2005); doi:10.1038/nbt1058
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article Specific and potent RNAi in the nucleus of human cells
G Brett Robb, Kirk M Brown, Jaspreet Khurana and Tariq M Rana Nature Structural and Molecular Biology12, 133–137
(February 2005); doi:10.1038/nsmb886
| Abstract | Full Text (HTML/PDF) |
research article Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation
Patrick Ng, Chia-Lin Wei, Wing-Kin Sung, Kuo Ping Chiu, Leonard Lipovich, Chin Chin Ang, Sanjay Gupta, Atif Shahab, Azmi Ridwan, Chee Hong Wong, Edison T Liu and Yijun Ruan Nature Methods2, 105–111
(February 2005); doi:10.1038/nmeth733
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news and views Transcriptome PETs: A genome's best friends
Brock A Peters and Victor E Velculescu Nature Methods2, 93–94
(February 2005); doi:10.1038/nmeth0205-93
| Abstract | Full Text (HTML/PDF) |
article Bcl-2 expression suppresses mismatch repair activity through inhibition of E2F transcriptional activity
Cha-Kyung Youn, Hyun-Ju Cho, Soo-Hyun Kim, Hong-Beum Kim, Mi-Hwa Kim, In-Youb Chang, Jung-Sup Lee, Myung-Hee Chung, Kyung-Soo Hahm and Ho Jin You Nature Cell Biology7, 137–147
(February 2005); doi:10.1038/ncb1215
| Abstract | Full Text (HTML/PDF) |
news and views A mismatched role for Bcl-2
Nicholas B. La Thangue Nature Cell Biology7, 101–102
(February 2005); doi:10.1038/ncb0205-101
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perspectives Innovation: Control of DNA replication and its potential clinical exploitation
Michael A. Gonzalez, Kiku-e K. Tachibana, Ronald A. Laskey and Nicholas Coleman Nature Reviews Cancer AOP published online 20 January 2005; doi:10.1038/nrc1548
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January
review article RNA polymerases I and III, growth control and cancer
Robert J. White Nature Reviews Molecular Cell Biology6, 69–78
(January 2005); doi:10.1038/nrm1551
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article Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome
Shin-ichi Horike, Shutao Cai, Masaru Miyano, Jan-Fang Cheng and Terumi Kohwi-Shigematsu Nature Genetics37, 31–40
(January 2005); doi:10.1038/ng1491
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news and views Synapsis or silence
John Schimenti Nature Genetics37, 11–13
(January 2005); doi:10.1038/ng0105-11
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research article Coordinate dual-gene transgenesis by lentiviral vectors carrying synthetic bidirectional promoters
Mario Amendola, Mary Anna Venneri, Alessandra Biffi, Elisa Vigna and Luigi Naldini Nature Biotechnology23, 108–116
(January 2005); doi:10.1038/nbt1049
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article Role of the proto-oncogene Pokemon in cellular transformation and ARF repression
Takahiro Maeda, Robin M. Hobbs, Taha Merghoub, Ilhem Guernah, Arthur Zelent, Carlos Cordon-Cardo, Julie Teruya-Feldstein and Pier Paolo Pandolfi Nature433, 278–285
(20 January 2005); doi:10.1038/nature03203
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letters to nature Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins
Alice E. Chen, David D. Ginty and Chen-Ming Fan Nature433, 317–322
(20 January 2005); doi:10.1038/nature03126
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news and views Signal transduction: A new canon
Olivier Pourquié Nature433, 208–209
(20 January 2005); doi:10.1038/433208a
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article Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment
Jonghwan Kim, Akshay A Bhinge, Xochitl C Morgan and Vishwanath R Iyer Nature Methods2, 47–53
(January 2005); doi:10.1038/nmeth726
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research article FGF-20 and DKK1 are transcriptional targets of β-catenin and FGF-20 is implicated in cancer and development
Mario N Chamorro, Donald R Schwartz, Alin Vonica, Ali H Brivanlou, Kathleen R Cho and Harold E Varmus EMBO Journal24, 73–84
(January 2005); doi:10.1038/sj.emboj.7600460
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article Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage
Michael Wanzel, Daniela Kleine-Kohlbrecher, Steffi Herold, Andreas Hock, Katrien Berns, Jongsun Park, Brian Hemmings and Martin Eilers Nature Cell Biology7, 30–41
(January 2005); doi:10.1038/ncb1202
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letter Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway
Alessandra Insinga, Silvia Monestiroli, Simona Ronzoni, Vania Gelmetti, Francesco Marchesi, Andrea Viale, Lucia Altucci, Clara Nervi, Saverio Minucci and Pier Giuseppe Pelicci Nature Medicine11, 71–76
(January 2005); doi:10.1038/nm1160
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letter Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain, Concetta Ambrosino, Paola Bontempo, Rosana Alvarez, Ettore M Schiavone, Felicetto Ferrara, Francesco Bresciani, Alessandro Weisz, Angel R de Lera, Hinrich Gronemeyer and Lucia Altucci Nature Medicine11, 77–84
(January 2005); doi:10.1038/nm1161
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review article RNAi-mediated pathways in the nucleus
Marjori A. Matzke and James A. Birchler Nature Reviews Genetics6, 24–35
(January 2005); doi:10.1038/nrg1500
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review article p53: traffic cop at the crossroads of DNA repair and recombination
Sagar Sengupta and Curtis C. Harris Nature Reviews Molecular Cell Biology6, 44–55
(January 2005); doi:10.1038/nrm1546
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article An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis
Alejandro Sweet-Cordero, Sayan Mukherjee, Aravind Subramanian, Han You, Jeffrey J Roix, Christine Ladd-Acosta, Jill Mesirov, Todd R Golub and Tyler Jacks Nature Genetics37, 48–55
(January 2005); doi:10.1038/ng1490
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news and views Cross-species comparisons of cancer signaling
Thomas G Graeber and Charles L Sawyers Nature Genetics37, 7–8
(January 2005); doi:10.1038/ng0105-7
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letter EGFR signaling attenuates Groucho-dependent repression to antagonize Notch transcriptional output
Peleg Hasson, Nirit Egoz, Clint Winkler, Gloria Volohonsky, Songtao Jia, Tama Dinur, Talila Volk, Albert J Courey and Ze'ev Paroush Nature Genetics37, 101–105
(January 2005); doi:10.1038/ng1486
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review article Drosophila, the golden bug, emerges as a tool for human genetics
Ethan Bier Nature Reviews Genetics6, 9–23
(January 2005); doi:10.1038/nrg1503
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article Protection of p27Kip1 mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation
Daniel Larocque, André Galarneau, Hsueh-Ning Liu, Michelle Scott, Guillermina Almazan and Stéphane Richard Nature Neuroscience8, 27–33
(January 2005); doi:10.1038/nn1359
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