article A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Laura J. Niedernhofer, George A. Garinis, Anja Raams, Astrid S. Lalai, Andria Rasile Robinson, Esther Appeldoorn, Hanny Odijk, Roos Oostendorp, Anwaar Ahmad, Wibeke van Leeuwen, Arjan F. Theil, Wim Vermeulen, Gijsbertus T. J. van der Horst, Peter Meinecke, Wim J. Kleijer, Jan Vijg, Nicolaas G. J. Jaspers and Jan H. J. Hoeijmakers Nature444, 1038–1043
(21 December 2006); doi:10.1038/nature05456
| Summary | Full Text (HTML / PDF) |
letter Early events in the thymus affect the balance of effector and regulatory T cells
Daniel J. Pennington, Bruno Silva-Santos, Tobias Silberzahn, Mónica Escórcio-Correia, Martin J. Woodward, Scott J. Roberts, Adrian L. Smith, P. Julian Dyson and Adrian C. Hayday Nature444, 1073–1077
(21 December 2006); doi:10.1038/nature05368
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letter Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
Kojiro Sato, Ayako Suematsu, Tomoki Nakashima, Sayaka Takemoto-Kimura, Kazuhiro Aoki, Yasuyuki Morishita, Hiroshi Asahara, Keiichi Ohya, Akira Yamaguchi, Toshiyuki Takai, Tatsuhiko Kodama, Talal A Chatila, Haruhiko Bito & Hiroshi Takayanagi Nature Medicine12, 1410–1416
(December 2006); doi:10.1038/nm1515
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letter A chromatin-mediated mechanism for specification of conditional transcription factor targets
Michael J Buck & Jason D Lieb Nature Genetics38, 1446–1451
(December 2006); doi:10.1038/ng1917
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article Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
Jongdae Lee, Ji-Hun Mo, Kyoko Katakura, Irit Alkalay, Adam N. Rucker, Yu-Tsueng Liu, Hyun-Ku Lee, Carol Shen, Gady Cojocaru, Steve Shenouda, Martin Kagnoff, Lars Eckmann, Yinon Ben-Neriah & Eyal Raz Nature Cell Biology8, 1327–1336
(December 2006); doi:10.1038/ncb1500
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article Control of thymocyte development and recombination-activating gene expression by the zinc finger protein Zfp608
Feng Zhang, Lance R Thomas, Eugene M Oltz & Thomas M Aune Nature Immunology7, 1309–1316
(December 2006); doi:10.1038/ni1397
| Summary | Full Text (HTML / PDF) |
news and views Fetal thymocyte development: putting a zinc finger on it?
Andrea C Carpenter & Craig H Bassing Nature Immunology7, 1285–1286
(December 2006); doi:10.1038/ni1206-1285
| Summary | Full Text (HTML / PDF) |
November
letter CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation
Leigh Ann Higa, Min Wu, Tao Ye, Ryuji Kobayashi, Hong Sun & Hui Zhang Nature Cell Biology8, 1277–1283
(November 2006); doi:10.1038/ncb1490
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brief communication DMP1 mutations in autosomal recessive hypophosphatemia implicate a bone matrix protein in the regulation of phosphate homeostasis
Bettina Lorenz-Depiereux, Murat Bastepe, Anna Benet-Pagès, Mustapha Amyere, Janine Wagenstaller, Ursula Müller-Barth, Klaus Badenhoop, Stephanie M Kaiser, Roger S Rittmaster, Alan H Shlossberg, José L Olivares, César Loris, Feliciano J Ramos, Francis Glorieux, Miikka Vikkula, Harald Jüppner & Tim M Strom Nature Genetics38, 1248–1250
(November 2006); doi:10.1038/ng1868
| Summary | Full Text (HTML / PDF) |
October
letter Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFκB-dependent transcription
Fei Gao, Jinke Cheng, Tong Shi & Edward T. H. Yeh Nature Chemical Biology8, 1171–1177
(2006); doi:10.1038/ncb1483
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article Transcription factors TFE3 and TFEB are critical for CD40 ligand expression and thymus-dependent humoral immunity
Chongmin Huan, Matthew L Kelly, Ryan Steele, Iuliana Shapira, Susan R S Gottesman, Christopher A J Roman Nature Immunology7, 1082–1091
(2006); doi:10.1038/ni1378
| First Paragraph | Full Text (HTML / PDF) |
news and views Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays
Meghana M Kulkarni, Matthew Booker, Serena J Silver, Adam Friedman, Pengyu Hong, Norbert Perrimon & Bernard Mathey-Prevot Nature Methods3, 833–838
(2006); doi:10.1038/nmeth935
| Summary | Full Text (HTML / PDF) |
article NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
Liming Pei, Hironori Waki, Bhavapriya Vaitheesvaran, Damien C Wilpitz, Irwin J Kurland & Peter Tontonoz Nature Medicine12, 1048–1055
(2006); doi:10.1038/nm1471
| Summary | Full Text (HTML / PDF) |
September
article Evolution of alternative transcriptional circuits with identical logic
Annie E. Tsong , Brian B. Tuch , Hao Li and Alexander D. Johnson Nature443, 415–420
(28 September 2006); doi:10.1038/nature05099
| Summary | Full Text (HTML / PDF) |
analysis JmjC-domain-containing proteins and histone demethylation
Robert J. Klose , Eric M. Kallin and Yi Zhang Nature Reviews Genetics7, 715–727
(September 2006); doi:10.1038/nrg1945
| Summary | Full Text (HTML / PDF) |
article NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
Liming Pei, Hironori Waki, Bhavapriya Vaitheesvaran, Damien C Wilpitz, Irwin J Kurland & Peter Tontonoz Nature Medicine12, 1048–1055
(2006); doi:10.1038/nm1471
| Summary |
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letter Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice
Mei Ding, Shiying Cui, Chengjin Li, Serge Jothy, Volker Haase, Brent M Steer, Philip A Marsden, Jeffrey Pippin, Stuart Shankland, Maria Pia Rastaldi, Clemens D Cohen, Matthias Kretzler & Susan E Quaggin Nature Medicine12, 1081–1087
(2006); doi:10.1038/nm1460
| Summary |
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news and views Hypoxia pathway linked to kidney failure
Gregg L Semenza Nature Medicine12, 996–997
(2006); doi:10.1038/nm0906-996
| Summary |
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letter JAK signaling globally counteracts heterochromatic gene silencing
Song Shi, Healani C Calhoun, Fan Xia, Jinghong Li, Long Le & Willis X Li Nature Genetics38, 1071–1076
(2006); doi:10.1038/ng1860
| Summary |
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news and views A Hopscotch-chromatin connection
Aurel Betz & James E Darnell Jr Nature Genetics38, 977–979
(2006); doi:10.1038/ng0906-977
| Summary |
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letter Unravelling the dynamics of RNA degradation by ribonuclease II and its RNA-bound complex
Carlos Frazão, Colin E. McVey, Mónica Amblar, Ana Barbas, Clemens Vonrhein, Cecília M. Arraiano and Maria A. Carrondoe Nature443, 110–114
(7 September 2006); doi:10.1038/nature05080
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letter Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage
Chuangui Wang, Lihong Chen, Xinghua Hou, Zhenyu Li, Neha Kabra, Yihong Ma, Shino Nemoto, Toren Finkel, Wei Gu, W. Douglas Cress & Jiandong Chen Nature Cell Biology8, 1025–1031
(6 August 2006); doi:10.1038/ncb1468
| Summary | Full Text (HTML / PDF) |
review Insulators: exploiting transcriptional and epigenetic mechanisms
Miklos Gaszner and Gary Felsenfeld Nature Reviews Genetics7, 703–713
(September 2006); doi:10.1038/nrg1925
| Summary | Full Text (HTML / PDF) |
letter Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo
Kip Nalley, Stephen Albert Johnston and Thomas Kodadek Nature442, 1054–1057
(31 August 2006); doi:10.1038/nature05067
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August
article RecA acts in trans to allow replication of damaged DNA by DNA polymerase V
Katharina Schlacher, Michael M. Cox, Roger Woodgate and Myron F. Goodman Nature442, 883–887
(24 August 2006); doi:10.1038/nature05042
| Summary | Full Text (HTML / PDF) |
letter Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification
Fabienne Cléard, Yuri Moshkin, François Karch & Robert K Maeda Nature Genetics12, 931–935
(August 2006); doi:10.1038/ng1833
| Summary | Full Text (HTML / PDF) |
review Tracking STAT nuclear traffic
Nancy C. Reich and Ling Liu Nature Review Immunology6, 602–612
(10 August 2006); doi:10.1038/nri1885
| Summary | Full Text (HTML / PDF) |
article Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing
Florian Heyd, Gerdy ten Dam & Tarik Möröy Nature Immunology7, 859–867
(August 2006); doi:10.1038/ni1361
| Summary | Full Text (HTML / PDF) |
article Foxp1 is an essential transcriptional regulator of B cell development
Hui Hu, Bin Wang, Madhuri Borde, Julie Nardone, Shan Maika, Laura Allred, Philip W Tucker & Anjana Rao Nature Immunology7, 819–826
(August 2006); doi:10.1038/ni1358
| Summary | Full Text (HTML / PDF) |
news and views FOXtrot and RAGtime in B cells
Fabio Savarese & Rudolf Grosschedl Nature Immunology7, 793–794
(August 2006); doi:10.1038/ni0806-793
| Summary | Full Text (HTML / PDF) |
article A comprehensive library of fluorescent transcriptional reporters for Escherichia coli
Alon Zaslaver, Anat Bren, Michal Ronen, Shalev Itzkovitz, Ilya Kikoin, Seagull Shavit, Wolfram Liebermeister, Michael G Surette & Uri Alon Nature Methods3, 623–638
(August 2006); doi:10.1038/nmeth895
| Summary | Full Text (HTML / PDF) |
July
letter ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
Andrea L. Bredemeyer, Girdhar G. Sharma, Ching-Yu Huang, Beth A. Helmink, Laura M. Walker, Katrina C. Khor, Beth Nuskey, Kathleen E. Sullivan, Tej K. Pandita, Craig H. Bassing and Barry P. Sleckman Nature442, 466–470
(27 July 2006); doi:10.1038/nature04866
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letter Suppression of vascular permeability and inflammation by targeting of the transcription factor c-Jun
Roger G Fahmy, Alla Waldman, Guishui Zhang, Ainslie Mitchell, Nicodemus Tedla, Hong Cai, Carolyn R Geczy, Colin N Chesterman, Michael Perry & Levon M Khachigian Nature Biotechnology24, 856–863
(July 2006); doi:10.1038/nbt1225
| Summary | Full Text (HTML / PDF) |
letter Kruppel-like factor 2 regulates thymocyte and T-cell migration
Corey M. Carlson, Bart T. Endrizzi, Jinghai Wu, Xiaojie Ding, Michael A. Weinreich, Elizabeth R. Walsh, Maqsood A. Wani, Jerry B. Lingrel, Kristin A. Hogquist and Stephen C. Jameson Nature442, 299–302
(20 July 2006); doi:10.1038/nature04882
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letter The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
Paul A. C. Cloos, Jesper Christensen, Karl Agger, Alessio Maiolica, Juri Rappsilber, Torben Antal, Klaus H. Hansen and Kristian Helin Nature442, 307–311
(20 July 2006); doi:10.1038/nature04837
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letter The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
Robert J. Klose, Kenichi Yamane, Yangjin Bae, Dianzheng Zhang, Hediye Erdjument-Bromage, Paul Tempst, Jiemin Wong and Yi Zhang Nature442, 312–316
(20 July 2006); doi:10.1038/nature04853
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letter CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
Daniel J Weisenberger, Kimberly D Siegmund, Mihaela Campan, Joanne Young, Tiffany I Long, Mark A Faasse, Gyeong Hoon Kang, Martin Widschwendter, Deborah Weener, Daniel Buchanan, Hoey Koh, Lisa Simms, Melissa Barker, Barbara Leggett, Joan Levine, Myungjin Kim, Amy J French, Stephen N Thibodeau, Jeremy Jass, Robert Haile & Peter W Laird Nature Genetics7, 787–793
(July 2006); doi:10.1038/ng1834
| Summary | Full Text (HTML / PDF) |
news and views CIMPle origin for promoter hypermethylation in colorectal cancer?
Kornel Schuebel, Wei Chen & Stephen B Baylin Nature Genetics7, 738–740
(July 2006); doi:10.1038/ng0706-738
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letter Regulation of RNA-polymerase-II-dependent transcription by N-WASP and its nuclear-binding partners
Xiaoyang Wu, Youngdong Yoo, Nataly N. Okuhama, Philip W. Tucker, Gang Liu & Jun-Lin Guan Nature Cell Biology8, 756–753
(11 June 2006); doi:10.1038/ncb1433
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news and views Actin's latest act: polymerizing to facilitate transcription?
Erwann Vieu & Nouria Hernandez Nature Cell Biology8, 650–651
(2006); doi:10.1038/ncb0706-650
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letter A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
Joanna Wysocka, Tomek Swigut, Hua Xiao, Thomas A. Milne, So Yeon Kwon, Joe Landry, Monika Kauer, Alan J. Tackett, Brian T. Chait, Paul Badenhorst, Carl Wu and C. David Allis Nature442, 86–90
(06 July 2006); doi:10.1038/nature04815
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letter Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF
Haitao Li, Serge Ilin, Wooikoon Wang, Elizabeth M. Duncan, Joanna Wysocka, C. David Allis and Dinshaw J. Patel Nature442, 91–95
(06 July 2006); doi:10.1038/nature04802
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article Regulation of naive T cell function by the NF-κB2 pathway
Naozumi Ishimaru, Hidehiro Kishimoto, Yoshio Hayashi & Jonathan Sprent Nature Immunology7, 763–772
(July 2006); doi:10.1038/ni1351
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article AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
Vikram R Rao, Sean A Pintchovski, Jeannie Chin, Carol L Peebles, Siddhartha Mitra & Steven Finkbeiner Nature Neuroscience7, 887–895
(July 2006); doi:10.1038/nn1708
| Summary | Full Text (HTML / PDF) |
June
letter CRD-BP mediates stabilization of ßTrCP1 and c-myc mRNA in response to ß-catenin signalling
Felicite K. Noubissi, Irina Elcheva, Neehar Bhatia, Abbas Shakoori, Andrei Ougolkov, Jianghuai Liu, Toshinari Minamoto, Jeff Ross, Serge Y. Fuchs and Vladimir S. Spiegelman Nature441, 898–901
(15 June 2006); doi:10.1038/nature04839
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letter Dual selection enhances the signaling specificity of a variant of the quorum-sensing transcriptional activator LuxR
Cynthia H Collins, Jared R Leadbetter & Frances H Arnold Nature Biotechnology24, 708–712
(June 2006); doi:10.1038/nbt1209
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news and views A luxRury of synthetic signals
Stephen W Michnick Nature Biotechnology24, 658–660
(June 2006); doi:10.1038/nbt0606-658
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article
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
Joseph R. Arron, Monte M. Winslow, Alberto Polleri, Ching-Pin Chang, Hai Wu, Xin Gao, Joel R. Neilson, Lei Chen, Jeremy J. Heit, Seung K. Kim, Nobuyuki Yamasaki, Tsuyoshi Miyakawa, Uta Francke, Isabella A. Graef and Gerald R. Crabtree Nature441, 595–600
(01 June 2006); doi:10.1038/nature04678
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letter A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
Yousang Gwack, Sonia Sharma, Julie Nardone, Bogdan Tanasa, Alina Iuga, Sonal Srikanth, Heidi Okamura, Diana Bolton, Stefan Feske, Patrick G. Hogan and Anjana Rao Nature441, 646–650
(01 June 2006); doi:10.1038/nature04631
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news and views Down's syndrome: Critical genes in a critical region
Charles J. Epstein Nature441, 582–583
(01 June 2006); doi:10.1038/441582a
| Full Text (HTML / PDF) |
letter Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells
Katia Ancelin, Ulrike C. Lange, Petra Hajkova, Robert Schneider, Andrew J. Bannister, Tony Kouzarides & M. Azim Surani
Published online: 14 May 2006
doi:10.1038/ncb1413
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article Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1
Tatsuya Saitoh, Adrian Tun-Kyi, Akihide Ryo, Masahiro Yamamoto, Greg Finn, Takashi Fujita, Shizuo Akira, Naoki Yamamoto, Kun Ping Lu & Shoji Yamaoka Nature Immunology7, 598–605
(June 2006); doi:10.1038/ni1347
| Summary | Full Text (HTML / PDF) |
news and views Pin-ning down immune responses to RNA viruses
Nadege Goutagny, Martina Severa & Katherine A Fitzgerald Nature Immunology7, 555–557
(June 2006); doi:10.1038/ni0606-555
| Summary | Full Text (HTML / PDF) |
May
article Gene expression changes and molecular pathways mediating activity-dependent plasticity in visual cortex
Daniela Tropea, Gabriel Kreiman, Alvin Lyckman, Sayan Mukherjee, Hongbo Yu, Sam Horng & Mriganka Sur Nature Neuroscience9, 660–668
(May 2006); doi:10.1038/nn1689
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article Synergy of glucose and growth hormone signalling in islet cells through ICA512 and STAT5
Hassan Mziaut, Mirko Trajkovski, Stephan Kersting, Armin Ehninger, Anke Altkrüger, Régis P. Lemaitre, Darja Schmidt, Hans–Detlev Saeger, Myung–Shik Lee, David N. Drechsel, Stefan Müller & Michele Solimena Nature Cell Biology8, 435 –445
(May 2006); doi:10.1038/ncb1395
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article Forkhead protein FoxO1 mediates Agrp–dependent effects of leptin on food intake
Tadahiro Kitamura, Yun Feng, Yukari Ido Kitamura, Streamson C Chua, Allison W Xu, Gregory S Barsh, Luciano Rossetti, Domenico Accili Nature Medicine12, 534–540
(May 2006); doi:10.1038/nm1392
| Summary | Full Text (HTML / PDF) |
article Transcriptional repressor Blimp-1 regulates T cell homeostasis and function
Gislâine A Martins, Luisa Cimmino, Miriam Shapiro-Shelef, Matthias Szabolcs, Alan Herron, Erna Magnusdottir & Kathryn Calame Nature Immunology7, 457–465
(May 2006) | doi:10.1038/ni1321
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article Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
Axel Kallies, Edwin D Hawkins, Gabrielle T Belz, Donald Metcalf, Mirja Hommel, Lynn M Corcoran, Philip D Hodgkin & Stephen L Nutt Nature Immunology7, 466–474
(May 2006) | doi:10.1038/ni1321
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news and views T cells join the Blimp-1 brigade
Pamela J Fink Nature Immunology7, 445–446
(May 2006) | doi:10.1038/ni0506-445
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April
review article Phenotypic variation in bacteria: the role of feedback regulation
Wiep Klaas Smits, Oscar P. Kuipers and Jan-Willem Veening Nature Reviews Microbiology4, 259–271
(April 2006); doi:10.1038/nrmicro1381
| Summary | Full Text (HTML / PDF) |
news and views Ageing: Chromatin unbound
Jan Vijg and Yousin Suh Nature440, 874–875
(13 April 2006); doi:10.1038/440874a
| Full Text (HTML / PDF) |
article MyD88-mediated stabilization of interferon-γ-induced cytokine and chemokine mRNA
Dongxu Sun & Aihao Ding Nature Immunology7, 375–381
(April 2006); doi:10.1038/ni1308
| First Paragraph
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news and views MyD88 beyond Toll
Jiahuai Han Nature Immunology7, 370–371
(April 2006); doi:10.1038/ni0406-370
| First Paragraph
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article The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
Yuin-Han Loh, Qiang Wu, Joon-Lin Chew, Vinsensius B Vega, Weiwei Zhang, Xi Chen, Guillaume Bourque, Joshy George, Bernard Leong, Jun Liu, Kee-Yew Wong, Ken W Sung, Charlie W H Lee, Xiao-Dong Zhao, Kuo-Ping Chiu, Leonard Lipovich, Vladimir A Kuznetsov, Paul Robson, Lawrence W Stanton, Chia-Lin Wei, Yijun Ruan, Bing Lim & Huck-Hui Ng Nature Genetics38, 431–440
(April 2006); doi:10.1038/ng1760
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March
letter Oncogenic activity of Cdc6 through repression of the INK4/ARF locus
Susana Gonzalez, Peter Klatt, Sonia Delgado, Esther Conde, Fernando Lopez-Rios, Montserrat Sanchez-Cespedes, Juan Mendez, Francisco Antequera and Manuel Serrano Nature440, 702–706
(30 March 2006); doi:10.1038/nature04585
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letter The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation
Irina Naguibneva, Maya Ameyar-Zazoua, Anna Polesskaya, Slimane Ait-Si-Ali, Reguina Groisman, Mouloud Souidi, Sylvain Cuvellier & Annick Harel-Bellan Nature Cell Biology8, 278–284
(30 March 2006); doi:10.1038/ncb1373
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review article A visual approach to proteomics
Stephan Nickell, Christine Kofler, Andrew P. Leis and Wolfgang Baumeister Nature Reviews Molecular Cell Biology7, 225–230
(30 March 2006); doi:10.1038/nrm1861
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letter Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
Struan F A Grant, Gudmar Thorleifsson, Inga Reynisdottir, Rafn Benediktsson, Andrei Manolescu, Jesus Sainz, Agnar Helgason, Hreinn Stefansson, Valur Emilsson, Anna Helgadottir, Unnur Styrkarsdottir, Kristinn P Magnusson, G Bragi Walters, Ebba Palsdottir, Thorbjorg Jonsdottir, Thorunn Gudmundsdottir, Arnaldur Gylfason, Jona Saemundsdottir, Robert L Wilensky, Muredach P Reilly, Daniel J Rader, Yu Bagger, Claus Christiansen, Vilmundur Gudnason, Gunnar Sigurdsson, Unnur Thorsteinsdottir, Jeffrey R Gulcher, Augustine Kong & Kari Stefansson Nature Genetics38, 320–323
(March 2006); doi:10.1038/ng1732
| Summary | Full Text (HTML / PDF) |
letter The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation
Jin-Won Lee and John D. Helmann Nature440, 363–367
(16 March 2006); doi:10.1038/nature04537
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article Feedback repression is required for mammalian circadian clock function
Trey K Sato, Rikuhiro G Yamada, Hideki Ukai, Julie E Baggs, Loren J Miraglia, Tetsuya J Kobayashi, David K Welsh, Steve A Kay, Hiroki R Ueda and John B Hogenesch Nature Genetics38, 312–319
(March 2006); doi:10.1038/ng1745
| Abstract | Full Text (HTML/PDF) |
review article N6-methyl-adenine: an epigenetic signal for DNA-protein interactions
Didier Wion and Josep Casadesús Nature Reviews Microbiology4, 183–192
(March 2006); doi:10.1038/nrmicro1350
| Abstract | Full Text (HTML/PDF) |
February
letter Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1
Davide Gabellini, Giuseppe D'Antona, Maurizio Moggio, Alessandro Prelle, Chiara Zecca, Raffaella Adami, Barbara Angeletti, Patrizia Ciscato, Maria Antonietta Pellegrino, Roberto Bottinelli, Michael R. Green and Rossella Tupler Nature439, 973–977
(23 February 2006); doi:10.1038/nature04422
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letter A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria
Till S. Voss, Julie Healer, Allison J. Marty, Michael F. Duffy, Jennifer K. Thompson, James G. Beeson, John C. Reeder, Brendan S. Crabb and Alan F. Cowman Nature439, 1004–1008
(23 February 2006); doi:10.1038/nature04407
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article Histone demethylation by a family of JmjC domain-containing proteins
Yu-ichi Tsukada, Jia Fang, Hediye Erdjument-Bromage, Maria E. Warren, Christoph H. Borchers, Paul Tempst and Yi Zhang Nature439, 811–816
(16 February 2006); doi:10.1038/nature04433
| Summary | Full Text (HTML / PDF) |
letter The Polycomb group protein EZH2 directly controls DNA methylation
Emmanuelle Viré, Carmen Brenner, Rachel Deplus, Loïc Blanchon, Mario Fraga, Céline Didelot, Lluis Morey, Aleyde Van Eynde, David Bernard, Jean-Marie Vanderwinden, Mathieu Bollen, Manel Esteller, Luciano Di Croce, Yvan de Launoit and François Fuks Nature439, 871–874
(16 February 2006); doi:10.1038/nature04431
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news and views Developmental biology: Two paths to silence merge
Panthea Taghavi and Maarten van Lohuizen Nature439, 794–795
(16 February 2006); doi:10.1038/439794a
| Full Text (HTML / PDF) |
letter The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
Jian-Fu Chen, Elizabeth M Mandel, J Michael Thomson, Qiulian Wu, Thomas E Callis, Scott M Hammond, Frank L Conlon and Da-Zhi Wang Nature Genetics38, 228–233
(February 2006); doi:10.1038/ng1725
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review article Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
Stephen B. Baylin and Joyce E. Ohm Nature Reviews Cancer6, 107–116
(February 2006); doi:10.1038/nrc1799
| Summary | Full Text (HTML / PDF) |
article The Runx1/AML1 transcription factor selectively regulates development and survival of TrkA nociceptive sensory neurons
Frèdèric Marmigére, Andreas Montelius, Michael Wegner, Yoram Groner, Louis F Reichardt and Patrik Ernfors Nature Neuroscience9, 180–187
(February 2006); doi:10.1038/nn1631
| Abstract | Full Text (HTML/PDF) |
news and views Specifying nociceptors
Annette Markus Nature Neuroscience9, 162
(February 2006); doi:10.1038/nn0206-162
| Full Text (HTML/PDF) |
January
letter Chromatin organization and cell fate switch respond to positional information in Arabidopsis
Silvia Costa and Peter Shaw Nature439, 493–496
(26 January 2006); doi:10.1038/nature04269
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article TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes
Yoshimi Nakagawa, Hitoshi Shimano, Tomohiro Yoshikawa, Tomohiro Ide, Mariko Tamura, Mika Furusawa, Takashi Yamamoto, Noriyuki Inoue, Takashi Matsuzaka, Akimitsu Takahashi, Alyssa H Hasty, Hiroaki Suzuki, Hirohito Sone, Hideo Toyoshima, Naoya Yahagi and Nobuhiro Yamada Nature Medicine12, 107–113
(January 2006); doi:10.1038/nm1334
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review article KLF4, p21 and context-dependent opposing forces in cancer
Benjamin D. Rowland and Daniel S. Peeper Nature Reviews Cancer6, 11–23
(January 2006); doi:10.1038/nrc1780
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article Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
Hubert Kettenberger, Alexander Eisenführ, Florian Brueckner, Mirko Theis, Michael Famulok and Patrick Cramer Nature Structural and Molecular Biology13, 44–48
(January 2006); doi:10.1038/nsmb1032
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news and views A SAGA of proteasomal ATPases
Sowmya Swaminathan Nature Cell Biology8, 13
(January 2006); doi:10.1038/ncb0106-13
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review article A PANorama of PAX genes in cancer and development
Ewan J. D. Robson, Shu-Jie He and Michael R. Eccles Nature Reviews Cancer6, 52–62
(January 2006); doi:10.1038/nrc1778
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article Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
Frank Rosenbauer, Bronwyn M Owens, Li Yu, Joseph R Tumang, Ulrich Steidl, Jeffery L Kutok, Linda K Clayton, Katharina Wagner, Marina Scheller, Hiromi Iwasaki, Chunhui Liu, Björn Hackanson, Koichi Akashi, Achim Leutz, Thomas L Rothstein, Christoph Plass and Daniel G Tenen Nature Genetics38, 27–37
(January 2006); doi:10.1038/ng1679
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article A single-molecule method for the quantitation of microRNA gene expression
Lori A Neely, Sonal Patel, Joanne Garver, Michael Gallo, Maria Hackett, Stephen McLaughlin, Mark Nadel, John Harris, Steve Gullans and Jenny Rooke Nature Methods3, 41–46
(January 2006); doi:10.1038/nmeth825
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letter RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
Sophie Dumont, Wei Cheng, Victor Serebrov, Rudolf K. Beran, Ignacio Tinoco Jr, Anna Marie Pyle and Carlos Bustamante Nature439, 105–108
(05 January 2006); doi:10.1038/nature04331
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article The human SWI/SNF subunit Brm is a regulator of alternative splicing
Eric Batsché, Moshe Yaniv and Christian Muchardt Nature Structural and Molecular Biology13, 22–29
(January 2006); doi:10.1038/nsmb1030
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news and views Chromatin, transcript elongation and alternative splicing
Alberto R Kornblihtt Nature Structural and Molecular Biology13, 5–7
(January 2006); doi:10.1038/nsmb0106-5
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