letter Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
Kristijan Ramadan et al. Nature450, 1258–1262
(20 December 2007); doi:10.1038/nature06388
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article Polyglutamine domain modulates the TBP–TFIIB interaction: implications for its normal function and neurodegeneration
Meyer J Friedman et al. Nature Neuroscience10, 1519–1528
(December 2007); doi:10.1038/nn2011
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article p38 MAPK signaling regulates recruitment of Ash2L-containing methyltransferase complexes to specific genes during differentiation
Shravanti Rampalli et al. Nature Structural & Molecular Biology14, 1150–1156
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letter Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3
Daniel O. Hart, Tamal Raha, Nathan D. Lawson & Michael R. Green Nature450, 1082–1085
(13 December 2007); doi:10.1038/nature06349
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article A YY1–INO80 complex regulates genomic stability through homologous recombination-based repair
Su Wu et al. Nature Structural & Molecular Biology14, 1165–1172
(December 2007); doi:10.1038/nsmb1332
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review TGFβ–SMAD signal transduction: molecular specificity and functional flexibility
Bernhard Schmierer & Caroline S. Hill Nature Reviews Molecular Cell Biology8, 970–982
(December 2007); doi:10.1038/nrm2297
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article Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
Jason S Stumhofer et al. Nature Immunology8, 1363–1371
(December 2007); doi:10.1038/ni1537
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article Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
Denise C Fitzgerald et al. Nature Immunology8, 1372–1379
(December 2007); doi:10.1038/ni1540
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article A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells
Amit Awasthi et al. Nature Immunology8, 1380–1389
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article TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
Mandy J McGeachy, Kristian S Bak-Jensen, Yi Chen, Cristina M Tato, Wendy Blumenschein, Terrill McClanahan & Daniel J Cua Nature Immunology8, 1390–1397
(December 2007); doi:10.1038/ni1539
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news and views IL-10 or not IL-10: that is the question
Dragana Jankovic & Giorgio Trinchieri Nature Immunology8, 1281–1283
(December 2007); doi:10.1038/ni1207-1281
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article Using expression profiling data to identify human microRNA targets
Jim C Huang et al. Nature Methods4, 1045–1049
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November
letter Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
Eric Dessaud et al. Nature450, 717–720
(29 November 2007); doi:10.1038/nature06347
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letter p53 regulates maternal reproduction through LIF
Wenwei Hu, Zhaohui Feng, Angelika K. Teresky & Arnold J. Levine Nature450, 721–724
(29 November 2007); doi:10.1038/nature05993
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news and views Reproduction: The unusual suspect
Colin L. Stewart Nature450, 619
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letter mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
John T. Cunningham, Joseph T. Rodgers, Daniel H. Arlow, Francisca Vazquez, Vamsi K. Mootha & Pere Puigserver Nature450, 736–740
(29 November 2007); doi:10.1038/nature06322
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review MLL translocations, histone modifications and leukaemia stem-cell development
Andrei V. Krivtsov & Scott A. Armstrong Nature Reviews Cancer7, 823–833
(November 2007); doi:10.1038/nrc2253
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article In vivo gene regulation in Salmonella spp. by a salicylate-dependent control circuit
José Luis Royo et al. Nature Methods4, 937–942
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news and views Pathogens on aspirin: promising research and therapeutic applications
Ohad Gal-Mor & B Brett Finlay Nature Methods4, 893–894
(November 2007); doi:10.1038/nmeth1107-893
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article STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression
Qian Zhang, Hong Y Wang, Xiaobin Liu & Mariusz A Wasik Nature Medicine13, 1341–1348
(November 2007); doi:10.1038/nm1659
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letter Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
Sandip Ray et al. Nature Medicine13, 1359–1362
(November 2007); doi:10.1038/nm1653
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review Specialization and evolution of endogenous small RNA pathways
Elisabeth J. Chapman & James C. Carrington Nature Reviews Genetics8, 884–896
(November 2007); doi:10.1038/nrg2179
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letter SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
Alejandro Vaquero, Michael Scher, Hediye Erdjument-Bromage, Paul Tempst, Lourdes Serrano & Danny Reinberg Nature450, 440–444
(15 November 2007); doi:10.1038/nature06268
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article prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast
Kum-Loong Boon et al. Nature Structural & Molecular Biology14, 1077–1083
(November 2007); doi:10.1038/nsmb1303
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letter Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
Kenta Yashiro, Hidetaka Shiratori & Hiroshi Hamada Nature450, 285–288
(8 November 2007); doi:10.1038/nature06254
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news and views Developmental biology: The power of blood
Paige Snider & Simon J. Conway Nature450, 180–181
(8 November 2007); doi:10.1038/450180a
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letter Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
Di Yu et al. Nature450, 299–303
(8 November 2007); doi:10.1038/nature06253
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review The emerging roles of forkhead box (Fox) proteins in cancer
Stephen S. Myatt & Eric W. -F. Lam Nature Reviews Cancer7, 847–859
(November 2007); doi:10.1038/nrc2223
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letter DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans
Julie Pinkston-Gosse & Cynthia Kenyon Nature Genetics39, 1403–1409
(November 2007); doi:10.1038/ng.2007.1
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news and views Aging and cancer: killing two birds with one worm
Anne Brunet Nature Genetics39, 1306–1307
(November 2007); doi:10.1038/ng1107-1306
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scientific report Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast
Milica Arneric & Joachim Lingner EMBO Reports8, 1080–1085
(November 2007); doi:10.1038/sj.embor.7401082
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review Neuronal regulation of alternative pre-mRNA splicing
Qin Li, Ji-Ann Lee & Douglas L. Black Nature Reviews Neuroscience8, 819–831
(November 2007); doi:10.1038/nrn2237
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article Comprehensive analysis of diverse ribonucleoprotein complexes
Marlene Oeffinger et al. Nature Methods4, 951–956
(November 2007); doi:10.1038/nmeth1101
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October
letter Purine-mediated signalling triggers eye development
Karine Massé, Surinder Bhamra, Robert Eason, Nicholas Dale & Elizabeth A. Jones Nature449, 1058–1062
(25 October 2007); doi:10.1038/nature06189
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letter An elaborate pathway required for Ras-mediated epigenetic silencing
Claude Gazin, Narendra Wajapeyee, Stephane Gobeil, Ching-Man Virbasius & Michael R. Green Nature449, 1073–1077
(25 October 2007); doi:10.1038/nature06251
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letter Protein arginine-methyltransferase-dependent oncogenesis
Ngai Cheung, Li Chong Chan, Alex Thompson, Michael L Cleary & Chi Wai Eric So Nature Cell Biology9, 1208–1215
(October 2007); doi:10.1038/ncb1642
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letter Interferon modulation of cellular microRNAs as an antiviral mechanism
Irene M. Pedersen et al. Nature449, 919–922
(18 October 2007); doi:10.1038/nature06205
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letter Inhibition of Crm1–p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation
Masayuki Kanai et al. Nature Cell Biology9, 1175–1183
(October 2007); doi:10.1038/ncb1638
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review Exporting RNA from the nucleus to the cytoplasm
Alwin Köhler & Ed Hurt Nature Reviews Molecular Cell Biology8, 761–773
(October 2007); doi:10.1038/nrm2255
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article A histone H3 lysine 27 demethylase regulates animal posterior development
Fei Lan, Peter E. Bayliss, John L. Rinn, Johnathan R. Whetstine, Jordon K. Wang, Shuzhen Chen, Shigeki Iwase, Roman Alpatov, Irina Issaeva, Eli Canaani, Thomas M. Roberts, Howard Y. Chang & Yang Shi Nature449, 689–694
(11 October 2007); doi:10.1038/nature06192
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letter UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development
Karl Agger, Paul A. C. Cloos, Jesper Christensen, Diego Pasini, Simon Rose, Juri Rappsilber, Irina Issaeva, Eli Canaani, Anna Elisabetta Salcini & Kristian Helin Nature449, 731–734
(11 October 2007); doi:10.1038/nature06145
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article 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR
Jung-Hyun Park, Stanley Adoro, Philip J Lucas, Sophia D Sarafova, Amala S Alag, Loretta L Doan, Batu Erman, Xiaolong Liu, Wilfried Ellmeier, Remy Bosselut, Lionel Feigenbaum & Alfred Singer Nature Immunology8, 1049–1059
(October 2007); doi:10.1038/ni1512
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news and views CD8+ T cells are kept in tune by modulating IL-7 responsiveness
Juan Carlos Zúñiga-Pflücker Nature Immunology8, 1027–1028
(October 2007); doi:10.1038/ni1007-1027
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article Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins, Govind Bhagat, Archana M Agarwal, Giuseppe Basso, Mireia Castillo, Satoru Nagase, Carlos Cordon-Cardo, Ramon Parsons, Juan Carlos Zúñiga-Pflücker, Maria Dominguez & Adolfo A Ferrando Nature Medicine13, 1203–1210
(October 2007); doi:10.1038/nm1636
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article The prolyl isomerase Pin1 orchestrates p53 acetylation and dissociation from the apoptosis inhibitor iASPP
Fiamma Mantovani, Francesca Tocco, Javier Girardini, Paul Smith, Milena Gasco, Xin Lu, Tim Crook & Giannino Del Sal Nature Structural & Molecular Biology14, 912–920
(October 2007); doi:10.1038/nsmb1306
| Summary | Full Text (HTML / PDF) |
news and views Multienzyme assembly of a p53 transcription complex
Ted R Hupp & Malcolm Walkinshaw Nature Structural & Molecular Biology14, 885–887
(October 2007); doi:10.1038/nsmb1007-885
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article Nucleolar release of Hand1 acts as a molecular switch to determine cell fate
David M. J. Martindill, Catherine A. Risebro, Nicola Smart, Maria Del Mar Franco-Viseras, Carla O. Rosario, Carol J. Swallow, James W. Dennis & Paul R. Riley Nature Cell Biology9, 1131–1141
(October 2007); doi:10.1038/ncb1633
| Summary | Full Text (HTML / PDF) |
news and views Cell fate in the Hand of Plk4
Marvin E. Tanenbaum & René H. Medemao Nature Cell Biology9, 1127–1129
(October 2007); doi:10.1038/ncb1007-1127
| Summary | Full Text (HTML / PDF) |
news and views Micromanaging metastasis
Alison Schuldt Nature Cell Biology9, 1121
(October 2007); doi:10.1038/ncb1007-1121
| Full Text (HTML / PDF) |
September
perspective Convergent extension and the hexahedral cell
Jeremy B. A. Green & Lance A. Davidson Nature Cell Biology9, 1010–1015
(September 2007); doi:10.1038/ncb438
| Summary | Full Text (HTML / PDF) |
review How stem cells age and why this makes us grow old
Norman E. Sharpless & Ronald A. DePinho Nature Reviews Molecular Cell Biology8, 703–713
(September 2007); doi:10.1038/nrm2241
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article IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
Liang Zhou, Ivaylo I Ivanov, Rosanne Spolski, Roy Min, Kevin Shenderov, Takeshi Egawa, David E Levy, Warren J Leonard & Dan R Littman Nature Immunology8, 967–974
(September 2007); doi:10.1038/ni1488
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perspective Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
Kelly A. Green & Jason S. Carroll Nature Reviews Cancer7, 713–722
(September 2007); doi:10.1038/nrc2211
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brief communication YY1 functions with INO80 to activate transcription
Yong Cai, Jingji Jin, Tingting Yao, Aaron J Gottschalk, Selene K Swanson, Su Wu, Yang Shi, Michael P Washburn, Laurence Florens, Ronald C Conaway & Joan W Conaway Nature Structural & Molecular Biology14, 872–874
(September 2007); doi:10.1038/nsmb1276
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article Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
Daisuke Kaida, Hajime Motoyoshi, Etsu Tashiro, Takayuki Nojima, Masatoshi Hagiwara, Ken Ishigami, Hidenori Watanabe, Takeshi Kitahara, Tatsuhiko Yoshida, Hidenori Nakajima, Tokio Tani, Sueharu Horinouchi & Minoru Yoshida Nature Chemical Biology3, 576–583
(September 2007); doi:10.1038/nchembio.2007.18
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letter Splicing factor SF3b as a target of the antitumor natural product pladienolide
Yoshihiko Kotake, Koji Sagane, Takashi Owa, Yuko Mimori-Kiyosue, Hajime Shimizu, Mai Uesugi, Yasushi Ishihama, Masao Iwata & Yoshiharu Mizui Nature Chemical Biology3, 570–575
(September 2007); doi:10.1038/nchembio.2007.16
| Summary | Full Text (HTML / PDF) |
news and views Targeting the spliceosome
Brian Rymond Nature Chemical Biology3, 533–535
(September 2007); doi:10.1038/nchembio0907-533
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article Development, cytokine profile and function of human interleukin 17-producing helper T cells
Nicholas J Wilson, Katia Boniface, Jason R Chan, Brent S McKenzie, Wendy M Blumenschein, Jeanine D Mattson, Beth Basham, Kathleen Smith, Taiying Chen, Franck Morel, Jean-Claude Lecron, Robert A Kastelein, Daniel J Cua, Terrill K McClanahan, Edward P Bowman & Rene de Waal Malefyt Nature Immunology8, 950–957
(September 2007); doi:10.1038/ni1497
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article Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17-producing human T helper cells
Eva V Acosta-Rodriguez, Giorgio Napolitani, Antonio Lanzavecchia & Federica Sallusto Nature Immunology8, 942–949
(September 2007); doi:10.1038/ni1496
| Summary | Full Text (HTML / PDF) |
article The development of inflammatory TH-17 cells requires interferon-regulatory factor 4
Anne Brüstle, Sylvia Heink, Magdalena Huber, Christine Rosenplänter, Christine Stadelmann, Philipp Yu, Enrico Arpaia, Tak W Mak, Thomas Kamradt & Michael Lohoff Nature Immunology8, 958–966
(September 2007); doi:10.1038/ni1500
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news and views TH-17 differentiation: of mice and men
Arian Laurence & John J O'Shea Nature Immunology8, 903–905
(September 2007); doi:10.1038/ni0907-903
| Full Text (HTML / PDF) |
review The role of nuclear architecture in genomic instability and ageing
Philipp Oberdoerffer & David A. Sinclair Nature Reviews Molecular Cell Biology8, 692–702
(September 2007); doi:10.1038/nrm2238
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article Genome-wide prediction of matrix attachment regions that increase gene expression in mammalian cells
Pierre-Alain Girod, Duc-Quang Nguyen, David Calabrese, Stefania Puttini, Mélanie Grandjean, Danielle Martinet, Alexandre Regamey, Damien Saugy, Jacques S Beckmann, Philipp Bucher & Nicolas Mermod Nature Methods4, 747–753
(2007); doi:10.1038/nmeth1076
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letter p53 is regulated by the lysine demethylase LSD1
Jing Huang, Roopsha Sengupta, Alexsandra B. Espejo, Min Gyu Lee, Jean A. Dorsey, Mario Richter, Susanne Opravil, Ramin Shiekhattar, Mark T. Bedford, Thomas Jenuwein & Shelley L. Berger Nature449, 105–108
(6 September 2007); doi:10.1038/nature06092
| Summary | Full Text (HTML / PDF) |
letter The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun
Ryo Koyama-Nasu, Gregory David & Naoko Tanese Nature Cell Biology9, 1074–1080
(September 2007); doi:10.1038/ncb1628
| Summary | Full Text (HTML / PDF) |
review Cellular senescence: when bad things happen to good cells
Judith Campisi & Fabrizio d'Adda di Fagagna Nature Reviews Molecular Cell Biology8, 729–740
(September 2007); doi:10.1038/nrm2233
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article Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
Craig L Maynard, Laurie E Harrington, Karen M Janowski, James R Oliver, Carlene L Zindl, Alexander Y Rudensky & Casey T Weaver Nature Immunology8, 931–941
(September 2007); doi:10.1038/ni1504
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news and views Regula'ten' the gut
Paulo Vieira & Anne O'Garra Nature Immunology8, 905–907
(September 2007); doi:10.1038/ni0907-905
| Full Text (HTML / PDF) |
August
letter Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome
Yoshiyuki Minegishi, Masako Saito, Shigeru Tsuchiya, Ikuya Tsuge, Hidetoshi Takada, Toshiro Hara, Nobuaki Kawamura, Tadashi Ariga, Srdjan Pasic, Oliver Stojkovic, Ayse Metin & Hajime Karasuyama Nature448, 1058–1062
(30 August 2007); doi:10.1038/nature06096
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article Cables links Robo-bound Abl kinase to N-cadherin-bound β-catenin to mediate Slit-induced modulation of adhesion and transcription
Jinseol Rhee, Tim Buchan, Lawrence Zukerberg, Jack Lilien & Janne Balsamo Nature Cell Biology9, 883–892
(August 2007); doi:10.1038/ncb1614
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news and views Gene expression analysis goes digital
Victor E Velculescu & Kenneth W Kinzler Nature Biotechnology25, 878–880
(August 2007); doi:10.1038/nbt0807-878
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letter An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus
Matthieu Giraud, Richard Taubert, Claire Vandiedonck, Xiayi Ke, Matthieu Lévi-Strauss, Franco Pagani, Francisco E. Baralle, Bruno Eymard, Christine Tranchant, Philippe Gajdos, Angela Vincent, Nick Willcox, David Beeson, Bruno Kyewski & Henri-Jean Garchon Nature448, 934–937
(23 August 2007); doi:10.1038/nature06066
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letter A central integrator of transcription networks in plant stress and energy signalling
Elena Baena-González, Filip Rolland, Johan M. Thevelein & Jen Sheen Nature448, 938–942
(23 August 2007); doi:10.1038/nature06069
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letter Genetic control of single lumen formation in the zebrafish gut
Michel Bagnat, Isla D. Cheung, Keith E. Mostov & Didier Y. R. Stainier Nature Cell Biology9, 954–960
(August 2007); doi:10.1038/ncb1621
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news and views It takes guts to make a single lumen
Heinz-Georg Belting & Markus Affolter Nature Cell Biology9, 880–881
(August 2007); doi:10.1038/ncb0807-880
| Summary | Full Text (HTML / PDF) |
article JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling
Bryan Thines, Leron Katsir, Maeli Melotto, Yajie Niu, Ajin Mandaokar, Guanghui Liu, Kinya Nomura, Sheng Yang He, Gregg A. Howe & John Browse Nature448, 661–665
(9 August 2007); doi:10.1038/nature05960
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article The JAZ family of repressors is the missing link in jasmonate signalling
A. Chini, S. Fonseca, G. Fernández, B. Adie, J. M. Chico, O. Lorenzo, G. García-Casado, I. López-Vidriero, F. M. Lozano, M. R. Ponce, J. L. Micol & R. Solano Nature448, 666–671
(9 August 2007); doi:10.1038/nature06006
| Summary | Full Text (HTML / PDF) |
news and views Plant biology: Jasmonate perception machines
Edward E. Farmer Nature448, 659–660
(9 August 2007); doi:10.1038/448659a
| Full Text (HTML / PDF) |
article PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation
Alessio Zippo, Alessandra De Robertis, Riccardo Serafini & Salvatore Oliviero Nature Cell Biology9, 932–944
(August 2007); doi:10.1038/ncb1618
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news and views PIM1 and MYC: a changing relationship?
Jean-Francois Naud & Martin Eilers Nature Cell Biology9, 873–875
(August 2007); doi:10.1038/ncb0807-873
| Summary | Full Text (HTML / PDF) |
news and views Debugging cellular reprogramming
In-Hyun Park & George Q. Daley Nature Cell Biology9, 871–873
(August 2007); doi:10.1038/ncb0807-871
| Summary | Full Text (HTML / PDF) |
article Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
Gordon Robertson, Martin Hirst, Matthew Bainbridge, Misha Bilenky, Yongjun Zhao, Thomas Zeng, Ghia Euskirchen, Bridget Bernier, Richard Varhol, Allen Delaney, Nina Thiessen, Obi L Griffith, Ann He, Marco Marra, Michael Snyder & Steven Jones Nature Methods4, 651–657
(August 2007); doi:10.1038/nmeth1068
| Summary | Full Text (HTML / PDF) |
news and views ChIP-seq: welcome to the new frontier
Elaine R Mardis Nature Methods4, 613–614
(August 2007); doi:10.1038/nmeth0807-613
| Summary | Full Text (HTML / PDF) |
scientific report RNA editing of the microRNA-151 precursor blocks cleavage by the Dicer–TRBP complex
Yukio Kawahara, Boris Zinshteyn, Thimmaiah P Chendrimada, Ramin Shiekhattar & Kazuko Nishikura EMBO Reports8, 763–769
(August 2007); doi:10.1038/sj.embor.7401011
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article Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3
Tom Taghon, Mary A Yui & Ellen V Rothenberg Nature Immunology8, 845–855
(August 2007); doi:10.1038/ni1486
| Summary | Full Text (HTML / PDF) |
news and views No DL1 Notch ligand? GATA be a mast cell
Susan Winandy & Melissa Brown Nature Immunology8, 796–797
(August 2007); doi:10.1038/ni0807-796
| Summary | Full Text (HTML / PDF) |
article Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping
Vanessa Vermeirssen, Bart Deplancke, M Inmaculada Barrasa, John S Reece-Hoyes, H Efsun Arda, Christian A Grove, Natalia J Martinez, Reynaldo Sequerra, Lynn Doucette-Stamm, Michael R Brent & Albertha J M Walhout Nature Methods4, 659–664
(August 2007); doi:10.1038/nmeth1063
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July
review Drosophila melanogaster embryonic haemocytes: masters of multitasking
Will Wood & Antonio Jacinto Nature Reviews Molecular Cell Biology8, 542–551
(July 2007); doi:10.1038/nrm2202
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review Gene methylation and early detection of genitourinary cancer: the road ahead
Paul Cairns Nature Reviews Cancer7, 531–543
(July 2007); doi:10.1038/nrc2170
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article Rhythmic growth explained by coincidence between internal and external cues
Kazunari Nozue, Michael F. Covington, Paula D. Duek, Séverine Lorrain, Christian Fankhauser, Stacey L. Harmer & Julin N. Maloof Nature448, 358–361
(19 July 2007); doi:10.1038/nature05946
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news and views Plant biology: Time for growth
Ghislain Breton & Steve A. Kay Nature448, 265–266
(19 July 2007); doi:10.1038/448265a
| Full Text (HTML / PDF) |
letter NUP98–NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
Gang G. Wang, Ling Cai, Martina P. Pasillas & Mark P. Kamps Nature Cell Biology9, 804–812
(July 2007); doi:10.1038/ncb1608
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review T cell development: better living through chromatin
Michael S Krangel Nature Immunology8, 687–694
(July 2007); doi:10.1038/ni1484
| Summary | Full Text (HTML / PDF) |
review Chromatin crosstalk in development and disease: lessons from REST
Lezanne Ooi & Ian C. Wood Nature Reviews Genetics8, 544–554
(July 2007); doi:10.1038/nrg2100
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article The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a
Sonia Guil & Javier F Cáceres Nature Structural & Molecular Biology14, 591–596
(July 2007); doi:10.1038/nsmb1250
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news and views Not miR-ly a splicing factor: hnRNP A1 succumbs to microRNA temptation
Anne Færch Nielsen, Philipp J F Leuschner & Javier Martinez Nature Structural & Molecular Biology14, 572–573
(July 2007); doi:10.1038/nsmb0707-572
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article A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila
Georg Dietzl, Doris Chen, Frank Schnorrer, Kuan-Chung Su, Yulia Barinova, Michaela Fellner, Beate Gasser, Kaolin Kinsey, Silvia Oppel, Susanne Scheiblauer, Africa Couto, Vincent Marra, Krystyna Keleman & Barry J. Dickson Nature448, 151–156
(12 July 2007); doi:10.1038/nature05954
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review The nuclear envelope and transcriptional control
Asifa Akhtar & Susan M. Gasser Nature Reviews Genetics8, 507–517
(July 2007); doi:10.1038/nrg2122
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brief communication Trawler: de novo regulatory motif discovery pipeline for chromatin immunoprecipitation
Laurence Ettwiller, Benedict Paten, Mirana Ramialison, Ewan Birney & Joachim Wittbrodt Nature Methods4, 563–565
(July 2007); doi:10.1038/nmeth1061
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June
review Stressing the role of FoxO proteins in lifespan and disease
Armando van der Horst & Boudewijn M.T. Burgering Nature Reviews Molecular Cell Biology8, 440–450
(June 2007); doi:10.1038/nrm2190
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review TGFβ signalling in control of T-cell-mediated self-reactivity
Yuri P Rubtsov & Alexander Y Rudensky Nature Reviews Immunology7, 443–453
(June 2007); doi:10.1038/nri2095
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letter Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia
Shannon E Mullican, Shuo Zhang, Marina Konopleva, Vivian Ruvolo, Michael Andreeff, Jeffrey Milbrandt & Orla M Conneely Nature Medicine13, 730–735
(June 2007); doi:10.1038/nm1579
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review Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
Héctor Peinado, David Olmeda & Amparo Cano Nature Reviews Cancer7, 415–428
(June 2007); doi:10.1038/nrc2131
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article Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans
Denis Dupuy, Nicolas Bertin, César A Hidalgo, Kavitha Venkatesan, Domena Tu, David Lee, Jennifer Rosenberg, Nenad Svrzikapa, Aurélie Blanc, Alain Carnec, Anne-Ruxandra Carvunis, Rock Pulak, Jane Shingles, John Reece-Hoyes, Rebecca Hunt-Newbury, Ryan Viveiros, William A Mohler, Murat Tasan, Frederick P Roth, Christian Le Peuch, Ian A Hope, Robert Johnsen, Donald G Moerman, Albert-László Barabási, David Baillie & Marc Vidal Nature Biotechnology25, 663–668
(June 2007); doi:10.1038/nbt1305
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news and views A green light to expression in time and space
Susan E Mango Nature Biotechnology25, 645–646
(June 2007); doi:10.1038/nbt0607-645
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article Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement
Xiaofang Yang, Roser Zaurin, Miguel Beato & Craig L Peterson Nature Structural & Molecular Biology14, 540–547
(June 2007); doi:10.1038/nsmb1238
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article Gene-specific control of inflammation by TLR-induced chromatin modifications
Simmie L. Foster, Diana C. Hargreaves & Ruslan Medzhitov Nature447, 972–978
(21 June 2007); doi:10.1038/nature05836
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news and views Immunology: Short-term memory
Benjamin N. Gantner & Harinder Singh Nature447, 916–917
(21 June 2007); doi:10.1038/447916a
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article Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages
Young Jun Kang, Sung Ouk Kim, Shigeki Shimada, Motoyuki Otsuka, Alim Seit-Nebi, Byoung S Kwon, Tania H Watts & Jiahuai Han Nature Immunology8, 601–609
(June 2007); doi:10.1038/ni1471
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article Retinaldehyde represses adipogenesis and diet-induced obesity
Ouliana Ziouzenkova, Gabriela Orasanu, Molly Sharlach, Taro E Akiyama, Joel P Berger, Jason Viereck, James A Hamilton, Guangwen Tang, Gregory G Dolnikowski, Silke Vogel, Gregg Duester & Jorge Plutzky Nature Medicine13, 695–702
(June 2007); doi:10.1038/nm1587
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news and views Retinaldehyde: more than meets the eye
Béatrice Desvergne Nature Medicine13, 671–673
(June 2007); doi:10.1038/nm0607-671
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brief communication Tissue-specific transcriptional regulation has diverged significantly between human and mouse
Duncan T Odom, Robin D Dowell, Elizabeth S Jacobsen, William Gordon, Timothy W Danford, Kenzie D MacIsaac, P Alexander Rolfe, Caitlin M Conboy, David K Gifford & Ernest Fraenkel Nature Genetics39, 730–732
(June 2007); doi:10.1038/ng2047
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article MicroRNA silencing through RISC recruitment of eIF6
Thimmaiah P. Chendrimada, Kenneth J. Finn, Xinjun Ji, David Baillat, Richard I. Gregory, Stephen A. Liebhaber, Amy E. Pasquinelli & Ramin Shiekhattar Nature447, 823–828
(14 June 2007); doi:10.1038/nature05841
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article Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
The ENCODE Project Consortium Analysis Coordination Chromatin and Replication Genes and Transcripts Integrated Analysis and Manuscript Preparation Management Group Multi-species Sequence Analysis Transcriptional Regulatory Elements UCSC Genome Browser Variation NISC Comparative Sequencing Program Baylor College of Medicine, Human Genome Sequencing Center Washington University Genome Sequencing Center Broad Institute Children's Hospital Oakland Research Institute Nature447, 799–816
(14 June 2007); doi:10.1038/nature05874
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letter Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation
Rolf Thermann & Matthias W. Hentze Nature447, 875–878
(14 June 2007); doi:10.1038/nature05878
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article The NEMO adaptor bridges the nuclear factor-κB and interferon regulatory factor signaling pathways
Tiejun Zhao, Long Yang, Qiang Sun, Meztli Arguello, Dean W Ballard, John Hiscott & Rongtuan Lin Nature Immunology8, 592–600
(June 2007); doi:10.1038/ni1465
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letter Decoding global gene expression programs in liver cancer by noninvasive imaging
Eran Segal, Claude B Sirlin, Clara Ooi, Adam S Adler, Jeremy Gollub, Xin Chen, Bryan K Chan, George R Matcuk, Christopher T Barry, Howard Y Chang & Michael D Kuo Nature Biotechnology25, 675–680
(June 2007); doi:10.1038/nbt1306
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article SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery
Matthew J Gamble & Robert P Fisher Nature Structural & Molecular Biology14, 548–555
(June 2007); doi:10.1038/nsmb1248
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brief communication Pervasive combinatorial modification of histone H3 in human cells
Benjamin A Garcia, James J Pesavento, Craig A Mizzen & Neil L Kelleher Nature Methods4, 487–489
(June 2007); doi:10.1038/nmeth1052
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article Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
Shinji Masui, Yuhki Nakatake, Yayoi Toyooka, Daisuke Shimosato, Rika Yagi, Kazue Takahashi, Hitoshi Okochi, Akihiko Okuda, Ryo Matoba, Alexei A. Sharov, Minoru S. H. Ko & Hitoshi Niwa Nature Cell Biology9, 625–635
(June 2007); doi:10.1038/ncb1589
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letter p73 supports cellular growth through c-Jun-dependent AP-1 transactivation
Faina Vikhanskaya, Wen Hong Toh, Iqbal Dulloo, Qiang Wu, Lakshmanane Boominathan, Huck Hui Ng, Karen H. Vousden & Kanaga Sabapathy Nature Cell Biology9, 698–706
(June 2007); doi:10.1038/ncb1598
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article PDLIM2-mediated termination of transcription factor NF-κB activation by intranuclear sequestration and degradation of the p65 subunit
Takashi Tanaka, Michael J Grusby & Tsuneyasu Kaisho Nature Immunology8, 584–591
(June 2007); doi:10.1038/ni1464
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article Two neurons mediate diet-restriction-induced longevity in C. elegans
Nicholas A. Bishop & Leonard Guarente Nature447, 545–549
(31 May 2007); doi:10.1038/nature05904
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article PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
Siler H. Panowski, Suzanne Wolff, Hugo Aguilaniu, Jenni Durieux & Andrew Dillin Nature447, 550–555
(31 May 2007); doi:10.1038/nature05837
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letter The histone H3K4 demethylase SMCX links REST target genes to X-linked mental retardation
Mamta Tahiliani, Pinchao Mei, Rui Fang, Thiago Leonor, Michael Rutenberg, Fumiko Shimizu, Jing Li, Anjana Rao & Yujiang Shi Nature447, 601–605
(31 May 2007); doi:10.1038/nature05823
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letter 8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins
Giovanni Maga, Giuseppe Villani, Emmanuele Crespan, Ursula Wimmer, Elena Ferrari, Barbara Bertocci & Ulrich Hübscher Nature447, 606–608
(31 May 2007); doi:10.1038/nature05843
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review Nuclear microenvironments in biological control and cancer
Sayyed K. Zaidi, Daniel W. Young, Amjad Javed, Jitesh Pratap, Martin Montecino, Andre van Wijnen, Jane B. Lian, Janet L. Stein & Gary S. Stein Nature Reviews Cancer7, 454–463
(June 2007); doi:10.1038/nrc2149
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review Network motifs: theory and experimental approaches
Uri Alon Nature Reviews Genetics7, 450–461
(June 2007); doi:10.1038/nrg2102
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scientific report Structural plasticity in the oestrogen receptor ligand-binding domain
Kendall W Nettles, John B Bruning, German Gil, Erin E O'Neill, Jason Nowak, Alun Hughs, Younchang Kim, Eugene R DeSombre, Robert Dilis, Robert N Hanson, Andrzej Joachimiak & Geoffrey L Greene EMBO Reports8, 563–568
(June 2007); doi:10.1038/sj.embor.7400963
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May
letter Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
Chang Liu, Siming Li, Tiecheng Liu, Jimo Borjigin & Jiandie D. Lin Nature447, 477–481
(24 May 2007); doi:10.1038/nature05767
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letter The neural progenitor-specifying activity of FoxG1 is antagonistically regulated by CKI and FGF
Tarik Regad, Martin Roth, Nicholas Bredenkamp, Nicola Illing & Nancy Papalopulu Nature Cell Biology9, 531–540
(May 2007); doi:10.1038/ncb1573
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article SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes
Rebecca Berdeaux, Naomi Goebel, Laura Banaszynski, Hiroshi Takemori, Thomas Wandless, G Diane Shelton & Marc Montminy Nature Medicine13, 597–603
(May 2007); doi:10.1038/nm1573
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letter Genetic reconstruction of a functional transcriptional regulatory network
Zhanzhi Hu, Patrick J Killion & Vishwanath R Iyer Nature Genetics39, 683–687
(May 2007); doi:10.1038/ng2012
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brief communication Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia
Idoya Lahortiga, Kim De Keersmaecker, Pieter Van Vlierberghe, Carlos Graux, Barbara Cauwelier, Frederic Lambert, Nicole Mentens, H Berna Beverloo, Rob Pieters, Frank Speleman, Maria D Odero, Marijke Bauters, Guy Froyen, Peter Marynen, Peter Vandenberghe, Iwona Wlodarska, Jules P P Meijerink & Jan Cools Nature Genetics39, 593–595
(May 2007); doi:10.1038/ng2025
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article H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing
Emeline Bouffartigues, Malcolm Buckle, Cyril Badaut, Andrew Travers & Sylvie Rimsky Nature Structural & Cell Biology14, 441–448
(May 2007); doi:10.1038/nsmb1233
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progress Manipulation of host Kruppel-like factor (KLF) function by exotoxins from diverse bacterial pathogens
Eoin O'Grady, Heidi Mulcahy, Claire Adams, John P. Morrissey & Fergal O'Gara Nature Reviews Microbiology5, 337–341
(May 2007); doi:10.1038/nrmicro1641
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review Foxp3 in control of the regulatory T cell lineage
Ye Zheng & Alexander Y Rudensky Nature Immunology8, 457–462
(May 2007); doi:10.1038/ni1455
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review Pax5: the guardian of B cell identity and function
César Cobaleda, Alexandra Schebesta, Alessio Delogu & Meinrad Busslinger Nature Immunology8, 463–470
(May 2007); doi:10.1038/ni1454
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brief communication CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock
Jason P DeBruyne, David R Weaver & Steven M Reppert Nature Neuroscience10, 543–545
(May 2007); doi:10.1038/nn1884
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review Epigenetic regulation in psychiatric disorders
Nadia Tsankova, William Renthal, Arvind Kumar & Eric J. Nestler Nature Reviews Neuroscience8, 355–545
(May 2007); doi:10.1038/nrn2132
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letter A chromatin link that couples cell division to root epidermis patterning in Arabidopsis
Elena Caro, M. Mar Castellano & Crisanto Gutierrez Nature447, 213–217
(10 May 2007); doi:10.1038/nature05763
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news and views Behavioural neuroscience: Down memory lane
J. David Sweatt Nature447, 151–152
(10 May 2007); doi:10.1038/nature05716
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letter Loss of Drosophila Myb interrupts the progression of chromosome condensation
J. Robert Manak, Hong Wen, Tran Van, Laura Andrejka & Joseph S. Lipsick Nature Cell Biology9, 581–587
(May 2007); doi:10.1038/ncb1580
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essay Blimp-1 over Budapest
Mark M Davis Nature Immunology8, 445–447
(May 2007); doi:10.1038/ni0507-445
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news and views A new way to regulate the NMJ
Kay E Davies & Tejvir S Khurana Nature Medicine13, 538–539
(May 2007); doi:10.1038/nm0507-538
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article Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE
Jane Tian, Ana Maria Avalos, Su-Yau Mao, Bo Chen, Kannaki Senthil, Herren Wu, Peggy Parroche, Stacey Drabic, Douglas Golenbock, Cherilyn Sirois, Jing Hua, Ling Ling An, Laurent Audoly, Greg La Rosa, Angelika Bierhaus, Peter Naworth, Ann Marshak-Rothstein, Mary K Crow, Katherine A Fitzgerald, Eicke Latz, Peter A Kiener & Anthony J Coyle Nature Immunology8, 487–496
(May 2007); doi:10.1038/ni1457
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news and views TLR9 and DNA 'feel' RAGE
Arthur M Krieg Nature Immunology8, 475–477
(May 2007); doi:10.1038/ni0507-475
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review Transcriptional regulation of vertebrate axon guidance and synapse formation
Franck Polleux, Gulayse Ince-Dunn & Anirvan Ghosh Nature Reviews Neuroscience8, 331–340
(May 2007); doi:10.1038/nrn2118
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article Imaging dynamics of endogenous mitochondrial RNA in single living cells
Takeaki Ozawa, Yutaka Natori, Moritoshi Sato & Yoshio Umezawa Nature Methods4, 413–419
(May 2007); doi:10.1038/nmeth1030
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article RNA visualization in live bacterial cells using fluorescent protein complementation
Maria Valencia-Burton, Ron M McCullough, Charles R Cantor & Natalia E Broude Nature Methods4, 421–427
(May 2007); doi:10.1038/nmeth1023
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brief communication A genomic integration method to visualize localization of endogenous mRNAs in living yeast
Liora Haim, Gadi Zipor, Stella Aronov & Jeffrey E Gerst Nature Methods4, 409–412
(May 2007); doi:10.1038/nmeth1040
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news and views Splitting or stacking fluorescent proteins to visualize mRNA in living cells
Sanjay Tyagi Nature Methods4, 391–392
(May 2007); doi:10.1038/nmeth0507-391
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April
article Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
Katharina Aschenbrenner, Louise M D'Cruz, Elisabeth H Vollmann, Maria Hinterberger, Jan Emmerich, Lee Kim Swee, Antonius Rolink & Ludger Klein Nature Immunology8, 351–358
(April 2007); doi:10.1038/ni1444
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article Regulatory T cell development in the absence of functional Foxp3
Wen Lin, Dipica Haribhai, Lance M Relland, Nga Truong, Marc R Carlson, Calvin B Williams & Talal A Chatila Nature Immunology8, 359–368
(April 2007); doi:10.1038/ni1445
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news and views Foxp3 and Aire in thymus-generated Treg cells: a link in self-tolerance
Takashi Nomura & Shimon Sakaguchi Nature Immunology8, 333–334
(April 2007); doi:10.1038/ni0407-333
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perspective FOXP3 modifies the phenotypic and functional properties of regulatory T cells
Daniel J. Campbell & Steven F. Ziegler Nature Reviews Immunology7, 305–310
(April 2007); doi:10.1038/nri2061
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article A module of negative feedback regulators defines growth factor signaling
Ido Amit, Ami Citri, Tal Shay, Yiling Lu, Menachem Katz, Fan Zhang, Gabi Tarcic, Doris Siwak, John Lahad, Jasmine Jacob-Hirsch, Ninette Amariglio, Nora Vaisman, Eran Segal, Gideon Rechavi, Uri Alon, Gordon B Mills, Eytan Domany & Yosef Yarden Nature Genetics39, 503–512
(April 2007); doi:10.1038/ng1987
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review Epigenetic signatures of stem-cell identity
Mikhail Spivakov and Amanda G. Fisher Nature Reviews Genetics8, 263–271
(April 2007); doi:10.1038/nrg2046
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letter An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation
Sunita Kumari, Anthony Bugaut, Julian L Huppert and Shankar Balasubramanian Nature Chemical Biology3, 218–221
(April 2007); doi:10.1038/nchembio864
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news and views The rule of four
Bruce A Armitage Nature Chemical Biology3, 203–204
(April 2007); doi:10.1038/nchembio0407-203
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article Opposing LSD1 complexes function in developmental gene activation and repression programmes
Jianxun Wang, Kathleen Scully, Xiaoyan Zhu, Ling Cai, Jie Zhang, Gratien G. Prefontaine, Anna Krones, Kenneth A. Ohgi, Ping Zhu, Ivan Garcia-Bassets, Forrest Liu, Havilah Taylor, Jean Lozach, Friederike L. Jayes, Kenneth S. Korach, Christopher K. Glass, Xiang-Dong Fu & Michael G. Rosenfeld Nature446, 882–887
(19 April 2007); doi:10.1038/nature05671
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technical report MRI detection of transcriptional regulation of gene expression in transgenic mice
Batya Cohen, Keren Ziv, Vicki Plaks, Tomer Israely, Vyacheslav Kalchenko, Alon Harmelin, Laura E Benjamin & Michal Neeman Nature Medicine13, 498–503
(April 2007); doi:10.1038/nm1497
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review Cancer epigenomics: DNA methylomes and histone-modification maps
Manel Esteller Nature Reviews Genetics8, 286–298
(April 2007); doi:10.1038/nrg2005
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letter Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
Masahiro Ono, Hiroko Yaguchi, Naganari Ohkura, Issay Kitabayashi, Yuko Nagamura, Takashi Nomura, Yoshiki Miyachi, Toshihiko Tsukada & Shimon Sakaguchi Nature446, 685–689
(5 April 2007); doi:10.1038/nature05673
| Summary | Full Text (HTML / PDF) |
letter Nuclear cytokine-activated IKKα controls prostate cancer metastasis by repressing Maspin
Jun-Li Luo, Wei Tan, Jill M. Ricono, Olexandr Korchynskyi, Ming Zhang, Steven L. Gonias, David A. Cheresh & Michael Karin Nature446, 690–694
(5 April 2007); doi:10.1038/nature05656
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March
letter Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2
Laëtitia K. Linares, Rosemary Kiernan, Robinson Triboulet, Christine Chable-Bessia, Daniel Latreille, Olivier Cuvier, Matthieu Lacroix, Laurent Le Cam, Olivier Coux & Monsef Benkirane Nature Cell Biology9, 331–338
(March 2007); doi:10.1038/ncb1545
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perspective The dynamic co-evolution of memory and regulatory CD4+ T cells in the periphery
Arne N. Akbar, Milica Vukmanovic-Stejic, Leonie S. Taams and Derek C. Macallan Nature Reviews Immunology7, 231–237
(March 2007); doi:10.1038/nri2037
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article Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3β activity
Chinmay M Trivedi, Yang Luo, Zhan Yin, Maozhen Zhang, Wenting Zhu, Tao Wang, Thomas Floss, Martin Goettlicher, Patricia Ruiz Noppinger, Wolfgang Wurst, Victor A Ferrari, Charles S Abrams, Peter J Gruber & Jonathan A Epstein Nature Medicine13, 324–331
(March 2007); doi:10.1038/nm1552
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article The gene encoding the splicing factor SF2/ASF is a proto-oncogene
Rotem Karni, Elisa de Stanchina, Scott W Lowe, Rahul Sinha, David Mu & Adrian R Krainer Nature Structural & Molecular Biology14, 185–193
(March 2007); doi:10.1038/nsmb1209
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news and views Splicing oncogenes
Anchang Hu & Xiang-Dong Fu Nature Structural & Molecular Biology14, 174–175
(March 2007); doi:10.1038/nsmb0307-174
| Summary | Full Text (HTML / PDF) |
letter Vitamin B6 conjugation to nuclear corepressor RIP140 and its role in gene regulation
M D Mostaqul Huq, Nien-Pei Tsai, Ya-Ping Lin, LeeAnn Higgins and Li-Na Wei Nature Chemical Biology3, 161–165
(March 2007); doi:10.1038/nchembio861
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letter Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
Taiping Chen, Sarah Hevi, Frédérique Gay, Naomi Tsujimoto, Timothy He, Bailin Zhang, Yoshihide Ueda & En Li Nature Genetics7, 391–396
(March 2007); doi:10.1038/ng1982
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news and views DNMT1 knockout delivers a strong blow to genome stability and cell viability
Kevin D Brown & Keith D Robertson Nature Genetics7, 289–290
(March 2007); doi:10.1038/ng0307-289
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review Light-regulated transcriptional networks in higher plants
Yuling Jiao, On Sun Lau and Xing Wang Deng Nature Reviews Genetics8, 217–230
(March 2007); doi:10.1038/nrg2049
| Summary | Full Text (HTML / PDF) |
letter Structure and function of the histone chaperone CIA/ASF1 complexed with histones H3 and H4
Ryo Natsume, Masamitsu Eitoku, Yusuke Akai, Norihiko Sano, Masami Horikoshi and Toshiya Senda Nature446, 338–341
(15 March 2007); doi:10.1038/nature05613
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news and views Stressed marrow: FoxOs stem tumour growth
Paul J. Coffer & Boudewijn M. T. Burgering Nature Cell Biology9, 251–253
(March 2007); doi:10.1038/ncb0307-251
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review Emerging roles of nuclear protein phosphatases
Greg B. G. Moorhead, Laura Trinkle-Mulcahy and Annegret Ulke-Lemée Nature Reviews Molecular Cell Biology8, 234–244
(March 2007); doi:10.1038/nrm2126
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article Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
Luke M Williams & Alexander Y Rudensky Nature Immunology8, 277–284
(March 2007); doi:10.1038/ni1437
| Summary | Full Text (HTML / PDF) |
news and views Regulatory T cell development: is Foxp3 the decider?
Tyler J Curiel Nature Medicine13, 250–253
(March 2007); doi:10.1038/nm0307-250
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scientific report Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymeraseη
Martha G Bomar, Ming-Tao Pai, Shiou-Ru Tzeng, Shawn Shun-Cheng Li & Pei Zhou EMBO reports8, 247 – 251
(March 2007); doi:10.1038/sj.embor.7400901
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article CIPC is a mammalian circadian clock protein without invertebrate homologues
Wen-Ning Zhao, Nikolay Malinin, Fu-Chia Yang, David Staknis, Nicholas Gekakis, Bert Maier, Silke Reischl, Achim Kramer & Charles J. Weitz Nature Cell Biology9, 268–275
(March 2007); doi:10.1038/ncb1539
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article MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast
Saurabh Paliwal, Pablo A. Iglesias, Kyle Campbell, Zoe Hilioti, Alex Groisman and Andre Levchenko Nature446, 46–51
(1 March 2007); doi:10.1038/nature05561
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review Strategies for silencing human disease using RNA interference
Daniel H. Kim and John J. Rossi Nature Reviews Genetics8, 173–184
(March 2007); doi:10.1038/nrg2006
| Summary | Full Text (HTML / PDF) |
article Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
Bethany A Janowski, Scott T Younger, Daniel B Hardy, Rosalyn Ram, Kenneth E Huffman and David R Corey Nature Chemical Biology3, 166–173
(March 2007); doi:10.1038/nchembio860
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news and views Per2 has time on its side
Urs Albrecht Nature Chemical Biology3, 139–140
(March 2007); doi:10.1038/nchembio0307-139
| Full Text (HTML / PDF) |
February
article A genome-wide association study identifies novel risk loci for type 2 diabetes
Robert Sladek, Ghislain Rocheleau, Johan Rung, Christian Dina, Lishuang Shen, David Serre, Philippe Boutin, Daniel Vincent, Alexandre Belisle, Samy Hadjadj, Beverley Balkau, Barbara Heude, Guillaume Charpentier, Thomas J. Hudson, Alexandre Montpetit, Alexey V. Pshezhetsky, Marc Prentki, Barry I. Posner, David J. Balding, David Meyre, Constantin Polychronakos and Philippe Froguel Nature445, 881–885
(22 February 2007); doi:10.1038/nature05616
| Summary | Full Text (HTML / PDF) |
letter Foxp3 occupancy and regulation of key target genes during T-cell stimulation
Alexander Marson, Karsten Kretschmer, Garrett M. Frampton, Elizabeth S. Jacobsen, Julia K. Polansky, Kenzie D. MacIsaac, Stuart S. Levine, Ernest Fraenkel, Harald von Boehmer and Richard A. Young Nature445, 931–935
(22 February 2007); doi:10.1038/nature05478
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article Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells
Ivana M Djuretic, Ditsa Levanon, Varda Negreanu, Yoram Groner, Anjana Rao & K Mark Ansel Nature Immunology8, 145–153
(February 2007); doi:10.1038/ni1424
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letter Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
Agnar Helgason, Snæbjörn Pálsson, Gudmar Thorleifsson, Struan F A Grant, Valur Emilsson, Steinunn Gunnarsdottir, Adebowale Adeyemo, Yuanxiu Chen, Guanjie Chen, Inga Reynisdottir, Rafn Benediktsson, Anke Hinney, Torben Hansen, Gitte Andersen, Knut Borch-Johnsen, Torben Jorgensen, Helmut Schäfer, Mezbah Faruque, Ayo Doumatey, Jie Zhou, Robert L Wilensky, Muredach P Reilly, Daniel J Rader, Yu Bagger, Claus Christiansen, Gunnar Sigurdsson, Johannes Hebebrand, Oluf Pedersen, Unnur Thorsteinsdottir, Jeffrey R Gulcher, Augustine Kong, Charles Rotimi & Kári Stefánsson Nature Genetics39, 218–225
(February 2007); doi:10.1038/ng1960
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letter Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
Abderrahmane Kaidi, Ann Caroline Williams & Christos Paraskeva Nature Cell Biology9, 210–217
(February 2007); doi:10.1038/ncb1534
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brief communication Epigenetic stem cell signature in cancer
Martin Widschwendter, Heidi Fiegl, Daniel Egle, Elisabeth Mueller-Holzner, Gilbert Spizzo, Christian Marth, Daniel J Weisenberger, Mihaela Campan, Joanne Young, Ian Jacobs & Peter W Laird Nature Genetics39, 157–158
(February 2007); doi:10.1038/ng1941
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review The evolution of gene regulation by transcription factors and microRNAs
Kevin Chen and Nikolaus Rajewsky Nature Reviews Genetics8, 93–103
(February 2007); doi:10.1038/nrg1990
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letter Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
Guillermo Barreto, Andrea Schäfer, Joachim Marhold, Dirk Stach, Suresh K. Swaminathan, Vikas Handa, Gabi Döderlein, Nicole Maltry, Wei Wu, Frank Lyko and Christof Niehrs Nature445, 671–675
(8 February 2007); doi:10.1038/nature05515
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review Multiple levels of cyclin specificity in cell-cycle control
Joanna Bloom and Frederick R. Cross Nature Reviews Molecular Cell Biology8, 149–160
(February 2007); doi:10.1038/nrm2105
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review Transcription factors in myeloid development: balancing differentiation with transformation
Frank Rosenbauer and Daniel G. Tenen Nature Reviews Immunology7, 105–117
(February 2007); doi:10.1038/nri2024
| Summary | Full Text (HTML / PDF) |
perspective Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
Paul A Marks & Ronald Breslow Nature Biotechnology25, 84–90
(February 2007); doi:10.1038/nbt1272
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letter Transcription factor control of asymmetric cell divisions that establish the stomatal lineage
Cora A. MacAlister, Kyoko Ohashi-Ito and Dominique C. Bergmann Nature445, 537–540
(1 February 2007); doi:10.1038/nature05491
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article Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors
June L Round, Lisa A Humphries, Tamar Tomassian, Paul Mittelstadt, Min Zhang & M Carrie Miceli Nature Immunology8, 154–161
(February 2007); doi:10.1038/ni1422
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news and views Choreography of MAGUKs during T cell activation
Mercedes Rincón & Roger J Davis Nature Immunology8, 126–127
(February 2007); doi:10.1038/ni0207-126
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January
letter Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2
Daniel W. Young, Mohammad Q. Hassan, Jitesh Pratap, Mario Galindo, Sayyed K. Zaidi, Suk-hee Lee, Xiaoqing Yang, Ronglin Xie, Amjad Javed, Jean M. Underwood, Paul Furcinitti, Anthony N. Imbalzano, Sheldon Penman, Jeffrey A. Nickerson, Martin A. Montecino, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen and Gary S. Stein Nature445, 442–446
(25 January 2007); doi:10.1038/nature05473
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article PDGF signaling specificity is mediated through multiple immediate early genes
Jennifer Schmahl, Christopher S Raymond & Philippe Soriano Nature Genetics39, 52–60
(January 2007); doi:10.1038/ng1922
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review Illuminating the silence: understanding the structure and function of small RNAs
Tariq M. Rana Nature Reviews Molecular Cell Biology8, 23–36
(January 2007); doi:10.1038/nrm2085
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article Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation
Peng Lu, Christine Vogel, Rong Wang, Xin Yao & Edward M Marcotte Nature Biotechnology25, 117–124
(January 2007); doi:10.1038/nbt1270
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brief communication Sensitive and specific method for detecting G protein-coupled receptor mRNAs
Arne Hansen, Yidong Chen, Jason M Inman, Quang N Phan, Zhi-Qing Qi, Charlie C Xiang, Miklos Palkovits, Natasha Cherman, Sergei A Kuznetsov, Pamela G Robey, Eva Mezey & Michael J Brownstein Nature Methods4, 35–37
(January 2007); doi:10.1038/nmeth977
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letter The nuclear receptor LXR is a glucose sensor
Nico Mitro, Puiying A. Mak, Leo Vargas, Cristina Godio, Eric Hampton, Valentina Molteni, Andreas Kreusch and Enrique Saez Nature445, 219–223
(11 January 2007); doi:10.1038/nature05449
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article An injected bacterial effector targets chromatin access for transcription factor NF-κB to alter transcription of host genes involved in immune responses
Laurence Arbibe, Dong Wook Kim, Eric Batsche, Thierry Pedron, Bogdan Mateescu, Christian Muchardt, Claude Parsot & Philippe J Sansonetti Nature Immunology8, 47–56
(January 2007); doi:10.1038/ni1423
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review Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Hua Yu, Marcin Kortylewski and Drew Pardoll Nature Reviews Immunology7, 41–51
(January 2007); doi:10.1038/nri1995
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article Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
Pavan Kumar P., Oliver Bischof, Prabhat Kumar Purbey, Dimple Notani, Henning Urlaub, Anne Dejean & Sanjeev Galande Nature Cell Biology9, 45–56
(January 2007); doi:10.1038/ncb1516
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review Integrating cell-signalling pathways with NF-κB and IKK function
Neil D. Perkins Nature Reviews Molecular Cell Biology8, 49–62
(January 2007); doi:10.1038/nrm2083
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