Research library: Transcription/Chromatin
2009:
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December
letter
Division and apoptosis of E2f-deficient retinal progenitors
Danian Chen et al.
Nature 462, 925–929
(17 December 2009); doi:10.1038/nature08544
| Summary | Full Text (HTML / PDF) |
letter
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells
Jean-Leon Chong et al.
Nature 462, 930–934
(17 December 2009); doi:10.1038/nature08677
| Summary | Full Text (HTML / PDF) |
review
Generating specificity and diversity in the transcriptional response to hypoxia
Urban Lendahl, Kian Leong Lee, Henry Yang & Lorenz Poellinger
Nature Reviews Genetics 10, 821–832
(December 2009); doi:10.1038/nrg2665
| Summary | Full Text (HTML / PDF) |
article
Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone
Celia Andreu-Agulló, José Manuel Morante-Redolat, Ana C Delgado & Isabel Fariñas
Nature Neuroscience 12, 1514–1523
(December 2009); doi:10.1038/nn.2437
| Summary | Full Text (HTML / PDF) |
news and views
Pigment epithelium-derived growth factor: modulating adult neural stem cell self-renewal
Andrew Chojnacki & Samuel Weiss
Nature Neuroscience 12, 1481–1483
(December 2009); doi:10.1038/nn1209-1481
| Full Text (HTML / PDF) |
brief communication
High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesis
Rupali P Patwardhan et al.
Nature Biotechnology 27, 1173–1175
(December 2009); doi:10.1038/nbt.1589
| Summary | Full Text (HTML / PDF) |
article
Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis
Benson C Lu et al.
Nature Genetics 41, 1295–1302
(December 2009); doi:10.1038/ng.476
| Summary | Full Text (HTML / PDF) |
article
Direct cell reprogramming is a stochastic process amenable to acceleration
Jacob Hanna et al.
Nature 462, 595–601
(03 December 2009); doi:10.1038/nature08592
| Full Text (HTML / PDF) |
letter
Regulation of adaptive behaviour during fasting by hypothalamic Foxa2
Jose P. Silva et al.
Nature 462, 646–650
(03 December 2009); doi:10.1038/nature08589
| Full Text (HTML / PDF) |
article
A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning
Daniel Kirilly et al.
Nature Neuroscience 12, 1497–1505
(December 2009); doi:10.1038/nn.2415
| Summary | Full Text (HTML / PDF) |
news and views
Neuronal death or dismemberment mediated by Sox14
Jeannette M Osterloh & Marc R Freeman
Nature Neuroscience 12, 1479–1480
(December 2009); doi:10.1038/nn1209-1479
| Full Text (HTML / PDF) |
November
letter
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
Yingli Sun et al.
Nature Cell Biology 11, 1376–1382
(1 November 2009) doi:10.1038/ncb1982
| Summary | Full Text (HTML / PDF) |
news and views
Tip60-ing the balance in DSB repair
Wolfgang Fischle
Nature Cell Biology 11, 1279–1281
(November 2009); doi:10.1038/ncb1109-1279
| Full Text (HTML / PDF) |
article
Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells
Dipayan Rudra et al.
Nature Immunology 10, 1170–1177
(November 2009); doi:10.1038/ni.1795
| Summary | Full Text (HTML / PDF) |
review
STATs in cancer inflammation and immunity: a leading role for STAT3
Hua Yu, Drew Pardoll & Richard Jove
Nature Reviews Cancer 9, 798–809
(November 2009); doi:10.1038/nrc2734
| Summary | Full Text (HTML / PDF) |
review
NFAT proteins: emerging roles in cancer progression
Maria Mancini & Alex Toker
Nature Reviews Cancer 9, 810–820
(November 2009); doi:10.1038/nrc2735
| Summary | Full Text (HTML / PDF) |
article
CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala
Yu Zhou et al.
Nature Neuroscience 12, 1438–1443
(November 2009); doi:10.1038/nn.2405
| Summary | Full Text (HTML / PDF) |
article
KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer
Kiranmai Gumireddy et al.
Nature Cell Biology 11, 1297–1304
(2009) doi:10.1038/ncb1974
| Summary | Full Text (HTML / PDF) |
letter
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease
Cristine Alves da Costa et al.
Nature Cell Biology 11, 1370–1375
(2009) doi:10.1038/ncb1981
| Summary | Full Text (HTML / PDF) |
review
Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
Mo Chen & James L. Manley
Nature Reviews Molecular Cell Biology 10, 741–754
(November 2009); doi:10.1038/nrm2777
| Summary | Full Text (HTML / PDF) |
letter
Foxo1 integrates insulin signaling with mitochondrial function in the liver
Zhiyong Cheng et al.
Nature Medicine 15, 1307–1311
(November 2009); doi:10.1038/nm.2049
| Summary | Full Text (HTML / PDF) |
review
Emerging roles of E2Fs in cancer: an exit from cell cycle control
Hui-Zi Chen, Shih-Yin Tsai & Gustavo Leone
Nature Reviews Cancer 9, 785–797
(November 2009); doi:10.1038/nrc2696
| Summary | Full Text (HTML / PDF) |
article
Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors
Eve Seuntjens et al.
Nature Neuroscience 12, 1373–1380
(November 2009); doi:10.1038/nn.2409
| Summary | Full Text (HTML / PDF) |
article
Involvement of a chromatin remodeling complex in damage tolerance during DNA replication
Karina B Falbo et al.
Nature Structural & Molecular Biology 16, 1167–1172
(November 2009); doi:10.1038/nsmb.1686
| Summary | Full Text (HTML / PDF) |
article
Emergent bistability by a growth-modulating positive feedback circuit
Cheemeng Tan, Philippe Marguet & Lingchong You
Nature Chemical Biology 5, 842–848
(November 2009); doi:10.1038/nchembio.218
| Summary | Full Text (HTML / PDF) |
article
Direct inhibition of the NOTCH transcription factor complex
Raymond E. Moellering et al.
Nature 462, 182–188
(12 November 2009); doi:10.1038/nature08543
| Full Text (HTML / PDF) |
news and views
Chemical biology: A Notch above other inhibitors
Paramjit S. Arora & Aseem Z. Ansari
Nature 462, 171–173
(12 November 2009); doi:10.1038/462171a
| Full Text (HTML / PDF) |
letter
Human-specific transcriptional regulation of CNS development genes by FOXP2
Genevieve Konopka et al.
Nature 462, 213–217
(12 November 2009); doi:10.1038/nature08549
| Full Text (HTML / PDF) |
news and views
Language evolution: The importance of being human
Martin H. Dominguez & Pasko Rakic
Nature 462, 169–170
(12 November 2009); doi:10.1038/462169a
| Full Text (HTML / PDF) |
article
Engineering splicing factors with designed specificities
Yang Wang, Cheom-Gil Cheong, Traci M Tanaka Hall & Zefeng Wang
Nature Methods 6, 825–830
(November 2009); doi:10.1038/nmeth.1379
| Summary | Full Text (HTML / PDF) |
scientific reports
RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair
Jingxin Wang et al.
EMBO Reports 10, 1272–1278
(November 2009); doi:10.1038/embor.2009.197
| Summary | Full Text (HTML / PDF) |
review
Polycomb group proteins: navigators of lineage pathways led astray in cancer
Adrian P. Bracken & Kristian Helin
Nature Reviews Cancer 9, 773–784
(November 2009); doi:10.1038/nrc2736
| Summary | Full Text (HTML / PDF) |
letter
SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
Adam J Bass et al.
Nature Genetics 41, 1238–1242
(November 2009); doi:10.1038/ng.465
| Summary | Full Text (HTML / PDF) |
October
article
C/EBPα and β couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation
Rodolphe G. Lopez et al.
Nature Cell Biology 11, 1181–1190
(October 2009); doi:10.1038/ncb1960
| Summary | Full Text (HTML / PDF) |
article
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
Duncan M Gascoyne et al.
Nature Immunology 10, 1118–1124
(October 2009); doi:10.1038/ni.1787
| Summary | Full Text (HTML / PDF) |
news and views
A defining factor for natural killer cell development
James P Di Santo
Nature Immunology 10, 1051–1052
(October 2009); doi:10.1038/ni1009-1051
| Full Text (HTML / PDF) |
article
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Leona Plum et al.
Nature Medicine 15, 1195–1201
(October 2009); doi:10.1038/nm.2026
| Summary | Full Text (HTML / PDF) |
article
Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia
Hoang Nguyen et al.
Nature Genetics 41, 1068–1075
(October 2009); doi:10.1038/ng.431
| Summary | Full Text (HTML / PDF) |
news and views
Tcf proteins are deeply rooted in skin
David M Owens
Nature Genetics 41, 1050–1051
(October 2009); doi:10.1038/ng1009-1050
| Full Text (HTML / PDF) |
article
SSB protein diffusion on single-stranded DNA stimulates RecA filament formation
Rahul Roy, Alexander G. Kozlov, Timothy M. Lohman & Taekjip Ha
Nature 461, 1092–1097
(22 October 2009); doi:10.1038/nature08442
| Full Text (HTML / PDF) |
news and views
Molecular biology: Slip sliding on DNA
Nicholas P. George & James L. Keck
Nature 461, 1067–1068
(22 October 2009); doi:10.1038/4611067a
| Full Text (HTML / PDF) |
review
Transcriptional control of the inflammatory response
Ruslan Medzhitov & Tiffany Horng
Nature Reviews Immunology 9, 692–703
(October 2009); doi:10.1038/nri2634
| Summary | Full Text (HTML / PDF) |
review
The expanding universe of p53 targets
Daniel Menendez, Alberto Inga & Michael A. Resnick
Nature Reviews Cancer 9, 724–737
(October 2009); doi:10.1038/nrc2730
| Summary | Full Text (HTML / PDF) |
article
AP2γ regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex
Luisa Pinto et al.
Nature Neuroscience 12, 1229–1237
(October 2009); doi:10.1038/nn.2399
| Summary | Full Text (HTML / PDF) |
news and views
Regional control of cortical lamination
Ronald R Waclaw & Kenneth Campbell
Nature Neuroscience 12, 1211–1212
(October 2009); doi:10.1038/nn1009-1211
| Full Text (HTML / PDF) |
letter
DNA demethylation in hormone-induced transcriptional derepression
Mi-Sun Kim et al.
Nature 461, 1007–1012
(15 October 2009); doi:10.1038/nature08456
| Full Text (HTML / PDF) |
article
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh
Rebecca Favaro et al.
Nature Neuroscience 12, 1248–1256
(October 2009); doi:10.1038/nn.2397
| Summary | Full Text (HTML / PDF) |
article
The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
Giulia Fontemaggi et al.
Nature Structural & Molecular Biology 16, 1086–1093
(October 2009); doi:10.1038/nsmb.1669
| Summary | Full Text (HTML / PDF) |
letter
JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin
Mark A. Dawson et al.
Nature 461, 819–822
(08 October 2009); doi:10.1038/nature08448
| Full Text (HTML / PDF) |
review
The cunning little vixen: Foxo and the cycle of life and death
Stephen M Hedrick
Nature Immunology 10, 1057–1063
(October 2009); doi:10.1038/ni.1784
| Summary | Full Text (HTML / PDF) |
review
p53 and E2f: partners in life and death
Shirley Polager & Doron Ginsberg
Nature Reviews Cancer 9, 738–748
(October 2009); doi:10.1038/nrc2718
| Summary | Full Text (HTML / PDF) |
article
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Shih-Min A. Huang et al.
Nature 461, 614–620
(01 October 2009); doi:10.1038/nature08356
| Full Text (HTML / PDF) |
news and views
Drug discovery: Propping up a destructive regime
Randall T. Peterson
Nature 461, 599–600
(01 October 2009); doi:10.1038/461599a
| Full Text (HTML / PDF) |
letter
Direct reprogramming of human neural stem cells by OCT4
Jeong Beom Kim et al.
Nature 461, 649–643
(01 October 2009); doi:10.1038/nature08436
| Full Text (HTML / PDF) |
letter
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
Jeanne Morinière et al.
Nature 461, 664–668
(01 October 2009); doi:10.1038/nature08397
| Full Text (HTML / PDF) |
letter
Ageing-related chromatin defects through loss of the NURD complex
Gianluca Pegoraro et al.
Nature Cell Biology 11, 1261–1267
(October 2009); doi:10.1038/ncb1971
| Summary | Full Text (HTML / PDF) |
article
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate
Andrea Ablasser et al.
Nature Immunology 10, 1065–1072
(October 2009); doi:10.1038/ni.1779
| Summary | Full Text (HTML / PDF) |
news and views
New DNA-sensing pathway feeds RIG-I with RNA
Xuetao Cao
Nature Immunology 10, 1049–1051
(October 2009); doi:10.1038/ni1009-1049
| Full Text (HTML / PDF) |
September
letter
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis
Baohong Zhao et al.
Nature Medicine 15, 1066–1071
(September 2009); doi:10.1038/nm.2007
| Summary | Full Text (HTML / PDF) |
review
Applying mass spectrometry-based proteomics to genetics, genomics and network biology
Matthias Gstaiger & Ruedi Aebersold
Nature Reviews Genetics 10, 617–627
(September 2009); doi:10.1038/nrg2633
| Summary | Full Text (HTML / PDF) |
analysis
Genome-wide identification of post-translational modulators of transcription factor activity in human B cells
Kai Wang et al.
Nature Biotechnology 27, 829–837
(September 2009); doi:10.1038/nbt.1563
| Summary | Full Text (HTML / PDF) |
review
Genetics of human gene expression: mapping DNA variants that influence gene expression
Vivian G. Cheung & Richard S. Spielman
Nature Reviews Genetics 10, 595–604
(September 2009); doi:10.1038/nrg2630
| Summary | Full Text (HTML / PDF) |
article
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity
Tobias B Dansen et al.
Nature Chemical Biology 5, 664–672
(September 2009); doi:10.1038/nchembio.194
| Summary | Full Text (HTML / PDF) |
review
Defining mechanisms that regulate RNA polymerase II transcription in vivo
Nicholas J. Fuda, M. Behfar Ardehali & John T. Lis
Nature 461, 186–192
(10 September 2009); doi:10.1038/nature08449
| Full Text (HTML / PDF) |
review
The logic of chromatin architecture and remodelling at promoters
Bradley R. Cairns
Nature 461, 193–198
(10 September 2009); doi:10.1038/nature08450
| Full Text (HTML / PDF) |
review
Genomic views of distant-acting enhancers
Axel Visel, Edward M. Rubin & Len A. Pennacchio
Nature 461, 199–205
(10 September 2009); doi:10.1038/nature08451
| Full Text (HTML / PDF) |
review
Implications of chimaeric non-co-linear transcripts
Thomas R. Gingeras
Nature 461, 206–211
(10 September 2009); doi:10.1038/nature08452
| Full Text (HTML / PDF) |
review
Chromosome crosstalk in three dimensions
Anita Göndör & Rolf Ohlsson
Nature 461, 212–217
(10 September 2009); doi:10.1038/nature08453
| Full Text (HTML / PDF) |
review
Molecular networks as sensors and drivers of common human diseases
Eric E. Schadt
Nature 461, 218–223
(10 September 2009); doi:10.1038/nature08454
| Full Text (HTML / PDF) |
article
Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
Diana A. Stavreva et al.
Nature Cell Biology 11, 1093–1102
(September 2009); doi:10.1038/ncb1922
| Summary | Full Text (HTML / PDF) |
news and views
Steroid hormone pulsing drives cyclic gene expression
Béatrice Desvergne & Christophe Héligon
Nature Cell Biology 11, 1051–1053
(September 2009); doi:10.1038/ncb0909-1051
| Full Text (HTML / PDF) |
article
T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-γ
Qing Yu et al.
Nature Immunology 10, 992–999
(September 2009); doi:10.1038/ni.1762
| Summary | Full Text (HTML / PDF) |
review
Insights from genomic profiling of transcription factors
Peggy J. Farnham
Nature Reviews Genetics 10, 605–616
(September 2009); doi:10.1038/nrg2636
| Summary | Full Text (HTML / PDF) |
review
Microfluidic devices for measuring gene network dynamics in single cells
Matthew R. Bennett & Jeff Hasty
Nature Reviews Genetics 10, 628–638
(September 2009); doi:10.1038/nrg2625
| Summary | Full Text (HTML / PDF) |
article
Cabin 1 restrains p53 activity on chromatin
Hyonchol Jang, Soo-Youn Choi, Eun-Jung Cho & Hong-Duk Youn
Nature Structural & Molecular Biology 16, 910–915
(September 2009); doi:10.1038/nsmb.1657
| Summary | Full Text (HTML / PDF) |
news and views
The p53 transcriptional synapse: activation on demand
Genrich V Tolstonog & Wolfgang Deppert
Nature Structural & Molecular Biology 16, 900–901
(September 2009); doi:10.1038/nsmb0909-900
| Full Text (HTML / PDF) |
August
letter
Initiation of myoblast to brown fat switch by a PRDM16–C/EBP-β transcriptional complex
Shingo Kajimura et al.
Nature 460, 1154–1158
(27 August 2009); doi:10.1038/nature08262
| Full Text (HTML / PDF) |
letter
A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF-β mediated epithelial–mesenchymal transition
Theresa Vincent et al.
Nature Cell Biology 11, 943–950
(August 2009); doi:10.1038/ncb1905
| Summary | Full Text (HTML / PDF) |
article
Specific pathways prevent duplication-mediated genome rearrangements
Christopher D. Putnam, Tikvah K. Hayes & Richard D. Kolodner
Nature 460, 984–989
(20 August 2009); doi:10.1038/nature08217
| Full Text (HTML / PDF) |
review
Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal
Myriam Hemberger, Wendy Dean & Wolf Reik
Nature Reviews Molecular Cell Biology 10, 526–537
(August 2009); doi:10.1038/nrm2727
| Summary | Full Text (HTML / PDF) |
article
Chd1 regulates open chromatin and pluripotency of embryonic stem cells
Alexandre Gaspar-Maia et al.
Nature 460, 863–868
(13 August 2009); doi:10.1038/nature08212
| Full Text (HTML / PDF) |
news and views
Stem cells: Escaping fates with open states
Robert J. Sims, III & Danny Reinberg
Nature 460, 802–803
(13 August 2009); doi:10.1038/460802a
| Full Text (HTML / PDF) |
July
review
Recent progress in the biology and physiology of sirtuins
Toren Finkel, Chu-Xia Deng & Raul Mostoslavsky
Nature 460, 587–591
(30 July 2009); doi:10.1038/nature08197
| Full Text (HTML / PDF) |
letter
BRIT1/MCPH1 links chromatin remodelling to DNA damage response
Guang Peng et al.
Nature Cell Biology 11, 865–872
(July 2009); doi:10.1038/ncb1895
| Summary | Full Text (HTML / PDF) |
article
The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states
Diane C DeZwaan, Oyetunji A Toogun, Frank J Echtenkamp & Brian C Freeman
Nature Structural & Molecular Biology 16, 711–716
(July 2009); doi:10.1038/nsmb.1616
| Summary | Full Text (HTML / PDF) |
research
Quantification of the yeast transcriptome by single-molecule sequencing
Doron Lipson et al.
Nature Biotechnology 27, 652–658
(July 2009); doi:10.1038/nbt.1551
| Summary | Full Text (HTML / PDF) |
article
Doxycycline-dependent photoactivated gene expression in eukaryotic systems
Sidney B Cambridge et al.
Nature Methods 6, 527–531
(July 2009); doi:10.1038/nmeth.1340
| Summary | Full Text (HTML / PDF) |
article
The active form of DNA polymerase V is UmuD'2C–RecA–ATP
Qingfei Jiang, Kiyonobu Karata, Roger Woodgate, Michael M. Cox & Myron F. Goodman
Nature 460, 359–363
(16 July 2009); doi:10.1038/nature08178
| Full Text (HTML / PDF) |
letter
The AP-1 transcription factor Batf controls TH17 differentiation
Barbara U. Schraml et al.
Nature 460, 405–409
(16 July 2009); doi:10.1038/nature08114
| Full Text (HTML / PDF) |
review
Transcription factories: gene expression in unions?
Heidi Sutherland & Wendy A. Bickmore
Nature Reviews Genetics 10, 457–466
(July 2009); doi:10.1038/nrg2592
| Summary | Full Text (HTML / PDF) |
article
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction
Feng Ye et al.
Nature Neuroscience 12, 829–838
(July 2009); doi:10.1038/nn.2333
| Summary | Full Text (HTML / PDF) |
news and views
Genetics meets epigenetics: HDACs and Wnt signaling in myelin development and regeneration
Huiliang Li & William D Richardson
Nature Neuroscience 12, 815–817
(July 2009); doi:10.1038/nn0709-815
| Full Text (HTML / PDF) |
letter
CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation
Ivan Zanoni et al.
Nature 460, 264–268
(09 July 2009); doi:10.1038/nature08118
| Full Text (HTML / PDF) |
article
The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon
Chen Wang et al.
Nature Immunology 10, 744–752
(July 2009); doi:10.1038/ni.1742
| Summary | Full Text (HTML / PDF) |
letter
REL, encoding a member of the NF-κB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis
Peter K Gregersen et al.
Nature Genetics 41, 820–823
(July 2009); doi:10.1038/ng.395
| Summary | Full Text (HTML / PDF) |
June
letter
TGF-β signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3
Anjali Shukla et al.
Nature Cell Biology 11, 777–784
(June 2009); doi:10.1038/ncb1885
| Summary | Full Text (HTML / PDF) |
article
Development of immunoglobulin λ-chain–positive B cells, but not editing of immunoglobulin κ-chain, depends on NF-κB signals
Emmanuel Derudder et al.
Nature Immunology 10, 647–654
(June 2009); doi:10.1038/ni.1732
| Summary | Full Text (HTML / PDF) |
article
Inhibition of osteoblastic bone formation by nuclear factor-κB
Jia Chang et al.
Nature Medicine 15, 682–689
(June 2009); doi:10.1038/nm.1954
| Summary | Full Text (HTML / PDF) |
article
A protective function for interleukin 17A in T cell–mediated intestinal inflammation
William O'Connor Jr et al.
Nature Immunology 10, 603–609
(June 2009); doi:10.1038/ni.1736
| Summary | Full Text (HTML / PDF) |
news and views
IL-17A directly inhibits TH1 cells and thereby suppresses development of intestinal inflammation
Amit Awasthi & Vijay K Kuchroo
Nature Immunology 10, 568–570
(June 2009); doi:10.1038/ni0609-568
| Full Text (HTML / PDF) |
article
Histone H4 lysine 16 acetylation regulates cellular lifespan
Weiwei Dang et al.
Nature 459, 802–807
(11 June 2009); doi:10.1038/nature08085
| Full Text (HTML / PDF) |
article
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
Meghan A Koch et al.
Nature Immunology 10, 595–602
(June 2009); doi:10.1038/ni.1731
| Summary | Full Text (HTML / PDF) |
news and views
Hybrid Treg cells: steel frames and plastic exteriors
Michael J Barnes & Fiona Powrie
Nature Immunology 10, 563–564
(June 2009); doi:10.1038/ni0609-563
| Full Text (HTML / PDF) |
letter
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
Jun K. Takeuchi & Benoit G. Bruneau
Nature 459, 708–711
(04 June 2009); doi:10.1038/nature08039
| Full Text (HTML / PDF) |
news and views
Developmental biology: The early heart remodelled
Fu-Sen Liang & Gerald R. Crabtree
Nature 459, 654–655
(04 June 2009); doi:10.1038/459654a
| Full Text (HTML / PDF) |
letter
F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
Manas K. Santra, Narendra Wajapeyee & Michael R. Green
Nature 459, 722–725
(04 June 2009); doi:10.1038/nature08011
| Full Text (HTML / PDF) |
May
article
RAD18 transmits DNA damage signalling to elicit homologous recombination repair
Jun Huang et al.
Nature Cell Biology 11, 592–603
(May 2009); doi:10.1038/ncb1865
| Summary | Full Text (HTML / PDF) |
article
Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells
Anne S Dejean et al.
Nature Immunology 10, 504–513
(May 2009); doi:10.1038/ni.1729
| Summary | Full Text (HTML / PDF) |
news and views
The Foxo and the hound: chasing the in vivo regulation of T cell populations during infection
Elia D Tait & Christopher A Hunter
Nature Immunology 10, 457–458
(May 2009); doi:10.1038/ni0509-457
| Full Text (HTML / PDF) |
review
Linking DNA methylation and histone modification: patterns and paradigms
Howard Cedar & Yehudit Bergman
Nature Reviews Genetics 10, 295–304
(May 2009); doi:10.1038/nrg2540
| Summary | Full Text (HTML / PDF) |
article
The nucleotide binding dynamics of human MSH2–MSH3 are lesion dependent
Barbara A L Owen, Walter H Lang & Cynthia T McMurray
Nature Structural & Molecular Biology 16, 550–557
(May 2009); doi:10.1038/nsmb.1596
| Summary | Full Text (HTML / PDF) |
letter
PEP1 regulates perennial flowering in Arabis alpina
Renhou Wang et al.
Nature 459, 423–427
(21 May 2009); doi:10.1038/nature07988
| Full Text (HTML / PDF) |
letter
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
Maximina H. Yun & Kevin Hiom
Nature 459, 460–463
(21 May 2009); doi:10.1038/nature07955
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article
Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
George A. Garinis et al.
Nature Cell Biology 11, 604–615
(May 2009); doi:10.1038/ncb1866
| Summary | Full Text (HTML / PDF) |
letter
Histone H2AX is integral to hypoxia-driven neovascularization
Matina Economopoulou et al.
Nature Medicine 15, 553–558
(May 2009); doi:10.1038/nm.1947
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news and views
Angiogenesis: escape from hypoxia
Mathew L Coleman & Peter J Ratcliffe
Nature Medicine 15, 491–493
(May 2009); doi:10.1038/nm0509-491
| Full Text (HTML / PDF) |
article
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line
The FANTOM Consortium & Riken Omics Science Center
Nature Genetics 41, 553–562
(May 2009); doi:10.1038/ng.375
| Summary | Full Text (HTML / PDF) |
article
Diversity-based, model-guided construction of synthetic gene networks with predicted functions
Tom Ellis, Xiao Wang & James J Collins
Nature Biotechnology 27, 465–471
(May 2009); doi:10.1038/nbt.1536
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news and views
Overpowering the component problem
Matthew R Bennett & Jeff Hasty
Nature Biotechnology 27, 450–451
(May 2009); doi:10.1038/nbt0509-450
| Full Text (HTML / PDF) |
letter
CBP/p300-mediated acetylation of histone H3 on lysine 56
Chandrima Das, M. Scott Lucia, Kirk C. Hansen & Jessica K. Tyler
Nature 459, 113–117
(07 May 2009); doi:10.1038/nature07861
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article
SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of β1-integrin
Dominique T. Brandt et al.
Nature Cell Biology 11, 557–568
(May 2009); doi:10.1038/ncb1862
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news and views
SCAI blocks MAL-evolent effects on cancer cell invasion
Rudy Juliano
Nature Cell Biology 11, 540–542
(May 2009); doi:10.1038/ncb0509-540
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letter
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
Brett S Carver et al.
Nature Genetics 41, 619–624
(May 2009); doi:10.1038/ng.370
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brief communication
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
Jennifer C King et al.
Nature Genetics 41, 524–526
(May 2009); doi:10.1038/ng.371
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news and views
TMPRSS2-ERG and PTEN loss in prostate cancer
Jeremy A Squire
Nature Genetics 41, 509–510
(May 2009); doi:10.1038/ng0509-509
| Full Text (HTML / PDF) |
article
miR-24–mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells
Ashish Lal et al.
Nature Structural & Molecular Biology 16, 492–498
(May 2009); doi:10.1038/nsmb.1589
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letter
WIP1 phosphatase is a negative regulator of NF-κB signalling
Joanne Chew et al.
Nature Cell Biology 11, 659–666
(May 2009); doi:10.1038/ncb1873
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April
article
Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination
Bao Q Vuong et al.
Nature Immunology 10, 420–426
(April 2009); doi:10.1038/ni.1708
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news and views
AID and RPA: PKA makes the connection local
Cristina Rada
Nature Immunology 10, 367–369
(April 2009); doi:10.1038/ni0409-367
| Full Text (HTML / PDF) |
review
The evolution of Fox genes and their role in development and disease
Sridhar Hannenhalli & Klaus H. Kaestner
Nature Reviews Genetics 10, 233–240
(April 2009); doi:10.1038/nrg2523
| Summary | Full Text (HTML / PDF) |
article
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells
Madeleine P Ball et al.
Nature Biotechnology 27, 361–368
(April 2009); doi:10.1038/nbt.1533
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news and views
Locking in on the human methylome
Benjamin P Berman, Daniel J Weisenberger & Peter W Laird
Nature Biotechnology 27, 341–342
(April 2009); doi:10.1038/nbt0409-341
| Full Text (HTML / PDF) |
scientific report
Phosphorylation of NF-κB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination
Hui Geng et al.
EMBO Reports 10, 381–386
(April 2009); doi:10.1038/embor200910
| Summary | Full Text (HTML / PDF) |
scientific report
NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes
Amanda J Fusco et al.
EMBO Reports 10, 152–159
(April 2009); doi:10.1038/embor2008227
| Summary | Full Text (HTML / PDF) |
letter
Gene regulatory logic of dopamine neuron differentiation
Nuria Flames & Oliver Hobert
Nature 458, 885–889
(16 April 2009); doi:10.1038/nature07929
| Summary | Full Text (HTML / PDF) |
news and views
Neuroscience: A bar code for differentiation
Nicholas C. Spitzer
Nature 41, 843–844
(16 April 2009); doi:10.1038/458843a
| Full Text (HTML / PDF) |
review
β-Catenin hits chromatin: regulation of Wnt target gene activation
Christian Mosimann, George Hausmann & Konrad Basler
Nature Reviews Molecular Cell Biology 10, 276–286
(April 2009); doi:10.1038/nrm2654
| Summary | Full Text (HTML / PDF) |
analysis
A census of human transcription factors: function, expression and evolution
Juan M. Vaquerizas, Sarah K. Kummerfeld, Sarah A. Teichmann & Nicholas M. Luscombe
Nature Reviews Genetics 10, 252–263
(April 2009); doi:10.1038/nrg2538
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March
letter
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cells
Daniel A. Lim et al.
Nature 458, 529–533
(26 March 2009); doi:10.1038/nature07726
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article
Signalling of the BCR is regulated by a lipid rafts-localised transcription factor, Bright
Christian Schmidt et al.
The EMBO Journal 28, 711–724
(March 2009); doi:10.1038/emboj.2009.20
| Summary | Full Text (HTML / PDF) |
letter
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
Ye Zheng et al.
Nature 458, 351–356
(19 March 2009); doi:10.1038/nature07674
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article
The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
Vanja Lazarevic et al.
Nature Immunology 10, 306–313
(March 2009); doi:10.1038/ni.1696
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news and views
Developing NKT cells need their calcium
Dale I Godfrey, Sanda Stankovic & Alan G Baxter
Nature Immunology 10, 231–233
(March 2009); doi:10.1038/ni0309-231
| Full Text (HTML / PDF) |
article
Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
Sandra Stehling-Sun, Jessica Dade, Stephen L Nutt, Rodney P DeKoter & Fernando D Camargo
Nature Immunology 10, 289–296
(March 2009); doi:10.1038/ni.1694
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news and views
Deciding the decider: Mef2c in hematopoiesis
Rachel M Gerstein
Nature Immunology 10, 235–236
(March 2009); doi:10.1038/ni0309-235
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February
article
A mechanosensitive transcriptional mechanism that controls angiogenesis
Akiko Mammoto et al.
Nature 457, 1103–1108
(26 February 2009); doi:10.1038/nature07765
| Summary | Full Text (HTML / PDF) |
article
CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
Masaaki Nishiyama et al.
Nature Cell Biology 11, 172–182
(February 2009); doi:10.1038/ncb1831
| Summary | Full Text (HTML / PDF) |
article
Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor
Yann M Kerdiles et al.
Nature Immunology 10, 176–184
(February 2009); doi:10.1038/ni.1689
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news and views
Homeostasis of naive T cells: the Foxo that fixes
Antonio A Freitas & Benedita Rocha
Nature Immunology 10, 133–134
(February 2009); doi:10.1038/ni0209-133
| Full Text (HTML / PDF) |
review
RUNX proteins in transcription factor networks that regulate T-cell lineage choice
Amélie Collins, Dan R. Littman & Ichiro Taniuchi
Nature Reviews Immunology 9, 106–115
(February 2009); doi:10.1038/nri2489
| Summary | Full Text (HTML / PDF) |
article
Biological basis for restriction of microRNA targets to the 3′ untranslated region in mammalian mRNAs
Shuo Gu, Lan Jin, Feijie Zhang, Peter Sarnow & Mark A Kay
Nature Structural & Molecular Biology 16, 144–150
(February 2009); doi:10.1038/nsmb.1552
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article
Recruitment of a chromatin remodelling complex by the Hog1 MAP kinase to stress genes
Glòria Mas et al.
The EMBO Journal 28, 326–336
(February 2009); doi:10.1038/emboj.2008.299
| Summary | Full Text (HTML / PDF) |
article
The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-κB and activate T cells
Sung-Gyoo Park et al.
Nature Immunology 10, 158–166
(February 2009); doi:10.1038/ni.1687
| Summary | Full Text (HTML / PDF) |
review
GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation
I-Cheng Ho, Tzong-Shyuan Tai & Sung-Yun Pai
Nature Reviews Immunology 9, 125–135
(February 2009); doi:10.1038/nri2476
| Summary | Full Text (HTML / PDF) |
research
Transgenic mice with defined combinations of drug-inducible reprogramming factors
Styliani Markoulaki et al.
Nature Biotechnology 27, 169–171
(February 2009); doi:10.1038/nbt.1520
| Summary | Full Text (HTML / PDF) |
article
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
Gene W Yeo et al.
Nature Structural & Molecular Biology 16, 130–137
(February 2009); doi:10.1038/nsmb.1545
| Summary | Full Text (HTML / PDF) |
letter
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
Michael J. Chen, Tomomasa Yokomizo, Brandon M. Zeigler, Elaine Dzierzak & Nancy A. Speck
Nature 457, 887–891
(12 February 2009); doi:10.1038/nature07619
| Summary | Full Text (HTML / PDF) |
letter
A stress-responsive RNA switch regulates VEGFA expression
Partho Sarothi Ray et al.
Nature 457, 915–919
(12 February 2009); doi:10.1038/nature07598
| Summary | Full Text (HTML / PDF) |
article
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer
Alessandra Rustighi et al.
Nature Cell Biology 11, 133–142
(February 2009); doi:10.1038/ncb1822
| Summary | Full Text (HTML / PDF) |
letter
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb
Bo Feng et al.
Nature Cell Biology 11, 197–203
(February 2009); doi:10.1038/ncb1827
| Summary | Full Text (HTML / PDF) |
review
Epigenetic control of T-helper-cell differentiation
Christopher B. Wilson, Emily Rowell & Masayuki Sekimata
Nature Reviews Immunology 9, 91–105
(February 2009); doi:10.1038/nri2487
| Summary | Full Text (HTML / PDF) |
article
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
Rafael A Irizarry et al.
Nature Genetics 41, 178–186
(February 2009); doi:10.1038/ng.298
| Summary | Full Text (HTML / PDF) |
article
CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis
Masaaki Nishiyama et al.
Nature Cell Biology 11, 172–182
(February 2009); doi:10.1038/ncb1831
| Summary | Full Text (HTML / PDF) |
review
The different faces of Notch in T-helper-cell differentiation
Derk Amsen, Andrey Antov & Richard A. Flavell
Nature Reviews Immunology 9, 116–124
(February 2009); doi:10.1038/nri2488
| Summary | Full Text (HTML / PDF) |
January
letter
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response
Marco A. Calzado, Laureano de la Vega, Andreas Möller, David D. L. Bowtell & M. Lienhard Schmitz
Nature Cell Biology 11, 85–91
(January 2009); doi:10.1038/ncb1816
| Summary | Full Text (HTML / PDF) |
review
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Michael Haberland, Rusty L. Montgomery & Eric N. Olson
Nature Reviews Genetics 10, 32–42
(January 2009); doi:10.1038/nrg2485
| Summary | Full Text (HTML / PDF) |
article
Histone H3 tail clipping regulates gene expression
Helena Santos-Rosa et al.
Nature Structural & Molecular Biology 16, 17–22
(January 2009); doi:10.1038/nsmb.1534
| Summary | Full Text (HTML / PDF) |
review
Small RNAs in transcriptional gene silencing and genome defence
Danesh Moazed
Nature 457, 413–420
(22 January 2009); doi:10.1038/nature07756
| Summary | Full Text (HTML / PDF) |
article
MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis
Ulrike Stein et al.
Nature Medicine 15, 59–67
(January 2009); doi:10.1038/nm.1889
| Summary | Full Text (HTML / PDF) |
letter
A tunable synthetic mammalian oscillator
Marcel Tigges, Tatiana T. Marquez-Lago, Jörg Stelling & Martin Fussenegger
Nature 457, 309–312
(15 January 2009); doi:10.1038/nature07616
| Summary | Full Text (HTML / PDF) |
news and views
Synthetic biology: The yin and yang of nature
Jeff Gore & Alexander van Oudenaarden
Nature 457, 271–272
(15 January 2009); doi:10.1038/457271a
| Full Text (HTML / PDF) |
letter
Altered circadian rhythms regulate growth vigour in hybrids and allopolyploids
Zhongfu Ni et al.
Nature 457, 327–331
(15 January 2009); doi:10.1038/nature07523
| Summary | Full Text (HTML / PDF) |
letter
Activation of ATM depends on chromatin interactions occurring before induction of DNA damage
Yong-Chul Kim et al.
Nature Cell Biology 11, 92–96
(January 2009); doi:10.1038/ncb1817
| Summary | Full Text (HTML / PDF) |
letter
Analysis of combinatorial cis-regulation in synthetic and genomic promoters
Jason Gertz, Eric D. Siggia & Barak A. Cohen
Nature 457, 215–218
(08 January 2009); doi:10.1038/nature07521
| Summary | Full Text (HTML / PDF) |
article
Apoptotic histone modification inhibits nuclear transport by regulating RCC1
Chi-Hang Wong et al.
Nature Cell Biology 11, 36–45
(January 2009); doi:10.1038/ncb1810
| Summary | Full Text (HTML / PDF) |
news and views
Ran out of the nucleus for apoptosis
Andrew Wilde & Yixian Zheng
Nature Cell Biology 11, 11–12
(January 2009); doi:10.1038/ncb0109-11
| Full Text (HTML / PDF) |
article
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells
Tom Cupedo et al.
Nature Immunology 10, 66–74
(January 2009); doi:10.1038/ni.1668
| Summary | Full Text (HTML / PDF) |
article
Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin
Carmelo Luci et al.
Nature Immunology 10, 75–82
(January 2009); doi:10.1038/ni.1681
| Summary | Full Text (HTML / PDF) |
article
RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
Stephanie L Sanos et al.
Nature Immunology 10, 83–91
(January 2009); doi:10.1038/ni.1684
| Summary | Full Text (HTML / PDF) |
news and views
Spotlight on IL-22-producing NK cell receptor-expressing mucosal lymphocytes
Karl-Johan Malmberg & Hans-Gustaf Ljunggren
Nature Immunology 10, 11–12
(January 2009); doi:10.1038/ni0109-11
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