review article The many faces of tumor necrosis factor in stroke
John M. Hallenbeck Nature Medicine8, 1363–1368
(December 2002); doi:10.1038/nm1202-1363
| Full Text (HTML/PDF) |
review article New therapeutics that antagonize endothelin: promises and frustrations
Giuseppe Remuzzi , Norberto Perico and Ariela Benigni Nature Reviews Drug Discovery1, 986–1001
(December 2002); doi:10.1038/nrd962
| Summary | Full Text (HTML / PDF) |
article A DNA vaccine against VEGF receptor 2 prevents effective angiogenesis and inhibits tumor growth
Andreas G. Niethammer, Rong Xiang, Jürgen C. Becker, Harald Wodrich, Ursula Pertl, Gabriele Karsten, Brian P. Eliceiri and Ralph A. Reisfeld Nature Medicine8, 1369–1375
(December 2002); doi:10.1038/nm794
| Abstract | Full Text (HTML/PDF) |
news and views Vessel maneuvers: Vaccine targets tumor vasculature
Michael S. O'Reilly Nature Medicine8, 1352–1353
(December 2002); doi:10.1038/nm1202-1352
| | Full Text (HTML/PDF) |
review article Bloodborne biomolecular markers in prostate cancer development and progression
Robert A. Bok and Eric J. Small Nature Reviews Cancer2, 918–926
(December 2002); doi:10.1038/nrc951
| Summary | Full Text (HTML / PDF) |
article Induction of angiogenesis in a mouse model using engineered transcription factors
Edward J. Rebar, Yan Huang, Reed Hickey, Anjali K. Nath, David Meoli, Sameer Nath, Bingliang Chen, Lei Xu, Yuxin Liang, Andrew C. Jamieson, Lei Zhang, S Kaye Spratt, Casey C. Case, Alan Wolffe and Frank J. Giordano Nature Medicine8, 1427–1432
(December 2002); doi:10.1038/nm795
| Abstract | Full Text (HTML/PDF) |
news and views Vessel maneuvers: Zinc fingers promote angiogenesis
Renata Pasqualini, Carlos F. Barbas and III Wadih Arap Nature Medicine8, 1353–1354
(December 2002); doi:10.1038/nm1202-1353
| Full Text (HTML/PDF) |
November
brief communication Membrane microviscosity regulates endothelial cell motility
Prabar K. Ghosh, Amit Vasanji, Gurunathan Murugesan, Steven J. Eppell, Linda M. Graham and Paul L. Fox Nature Cell Biology4, 894–900
(November 2002); doi:10.1038/ncb873
| First Paragraph | Full Text (HTML/PDF) |
review article Platelets in atherothrombosis
Zaverio M. Ruggeri Nature Medicine8, 1227–1234
(November 2002); doi:10.1038/nm1102-1227
| Abstract | Full Text (HTML/PDF) |
review article Innate and acquired immunity in atherogenesis
Christoph J. Binder, Mi-Kyung Chang, Peter X. Shaw, Yury I. Miller, Karsten Hartvigsen, Asheesh Dewan and Joseph L. Witztum Nature Medicine8, 1218–1226
(November 2002); doi:10.1038/nm1102-1218
| Abstract | Full Text (HTML/PDF) |
review article The macrophage foam cell as a target for therapeutic intervention
Andrew C. Li and Christopher K. Glass Nature Medicine8, 1235–1242
(November 2002); doi:10.1038/nm1102-1235
| Abstract | Full Text (HTML/PDF) |
October
article Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
Lidija Covic, Meghna Misra, Jehangir Badar, Christopher Singh and Athan Kuliopulos Nature Medicine8, 1161–1165
(October 2002); doi:10.1038/nm760
| First Paragraph | Full Text (HTML/PDF) |
news and views Attacked from within, blood thins
Wadie F. Bahou Nature Medicine8, 1082–1083
(October 2002); doi:10.1038/nm1002-1082
| Full Text (HTML/PDF) |
review article Clinical translation of angiogenesis inhibitors
Robert Kerbel and Judah Folkman Nature Reviews Cancer2, 727–739
(October 2002); doi:10.1038/nrc905
| Summary | Full Text (HTML / PDF) |
letter Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy
Johane Robitaille, Marcia L.E. MacDonald, Ajamete Kaykas, Laird C. Sheldahl, Jutta Zeisler, Marie-Pierre Dubé, Lin-Hua Zhang, Roshni R. Singaraja, Duane L. Guernsey, Binyou Zheng, Lee F. Siebert, Ann Hoskin-Mott, Michael T. Trese, Simon N. Pimstone, Barkur S. Shastry, Randall T. Moon, Michael R. Hayden, Y. Paul Goldberg and Mark E. Samuels Nature Genetics32, 326–330
(October 2002); doi:10.1038/ng957
| First Paragraph | Full Text (HTML/PDF) |
perspectives Timeline: VEGF and the quest for tumour angiogenesis factors
Napoleone Ferrara Nature Reviews Cancer2, 795–803
(October 2002); doi:10.1038/nrc909
| Summary | Full Text (HTML / PDF) |
September
commentary A reevaluation of integrins as regulators of angiogenesis
Richard O. Hynes Nature Medicine8, 918–921
(September 2002); doi:10.1038/nm0902-918
| Full Text (HTML/PDF) |
review article Phosphodiesterase 5 inhibitors: current status and potential applications
David P. Rotella Nature Reviews Drug Discovery1, 674–682
(September 2002); doi:10.1038/nrd893
| Summary | Full Text (HTML / PDF) |
commentary Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis
Jennifer LeCouter, Rui Lin and Napoleone Ferrara Nature Medicine8, 913–917
(September 2002); doi:10.1038/nm0902-913
| Full Text (HTML/PDF) |
review article Arteries and veins: making a difference with zebrafish
Nathan D. Lawson and Brant M. Weinstein Nature Reviews Genetics3, 674–682
(September 2002); doi:10.1038/nrg888
| Summary | Full Text (HTML / PDF) |
letters to nature Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation
Nabeel Bardeesy, Manisha Sinha, Aram F. Hezel, Sabina Signoretti, Nathaniel A. Hathaway, Norman E. Sharpless, Massimo Loda, Daniel R. Carrasco and Ronald A. DePinho Nature419, 162–167
(12 September 2002); doi:10.1038/nature01045
| First Paragraph | Full Text (HTML / PDF) |
news and views Cancer: Stuck at first base
Louise van der Weyden, Jos Jonkers and Allan Bradley Nature 419, 127–128
(12 September 2002); doi:10.1038/419127a
| Full Text (HTML/PDF) |
review article Molecular basis of the VHL hereditary cancer syndrome
William G. Kaelin Jr Nature Reviews Cancer2, 673–682
(September 2002); doi:10.1038/nrc885
| Abstract | Full Text (HTML/PDF) |
letters to nature RNA aptamers as reversible antagonists of coagulation factor IXa
Christopher P. Rusconi, Elizabeth Scardino, Juliana Layzer, George A. Pitoc, Thomas L. Ortel, Dougald Monroe and Bruce A. Sullenger Nature419, 90–94
(05 September 2002); doi:10.1038/nature00963
| First Paragraph | Full Text (HTML / PDF) |
news and views Medicine: RNA as drug and antidote
Edward Tuddenham Nature419, 23–24
(05 September 2002); doi:10.1038/419023a
| Full Text (HTML / PDF) |
article Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor
Manjiri M. Bakre, Yuhong Zhu, Hong Yin, Doug W. Burton, Robert Terkeltaub, Leonard J. Deftos and Judith A. Varner Nature Medicine8, 995–1003
(September 2002); doi:10.1038/nm753
| Abstract | Full Text (HTML/PDF) |
article Inhibitor of apoptosis protein survivin regulates vascular injury
Olivier P. Blanc-Brude, Jun Yu, Hector Simosa, Michael S. Conte, William C. Sessa and Dario C. Altieri Nature Medicine8, 987–994
(September 2002); doi:10.1038/nm750
| Abstract | Full Text (HTML/PDF) |
August
article Heart-valve mesenchyme formation is dependent on hyaluronan-augmented activation of ErbB2-ErbB3 receptors
Todd D. Camenisch, Joyce A. Schroeder, Judy Bradley, Scott E. Klewer and John A. McDonald Nature Medicine8, 850–855
(August 2002); doi:10.1038/nm742
| Abstract | Full Text (HTML/PDF) |
article Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
Aernout Luttun, Marc Tjwa, Lieve Moons, Yan Wu, Anne Angelillo-Scherrer, Fang Liao, Janice A. Nagy, Andrea Hooper, Josef Priller, Bert De Klerck, Veerle Compernolle, Evis Daci, Peter Bohlen, Mieke Dewerchin, Jean-Marc Herbert, Roy Fava, Patrick Matthys, Geert Carmeliet, Désiré Collen, Harold F. Dvorak, Daniel J. Hicklin and Peter Carmeliet Nature Medicine8, 831–840
(August 2002); doi:10.1038/nm731
| Abstract | Full Text (HTML/PDF) |
article Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment
Koichi Hattori, Beate Heissig, Yan Wu, Sergio Dias, Rafael Tejada, Barbara Ferris, Daniel J. Hicklin, Zhenping Zhu, Peter Bohlen, Larry Witte, Jan Hendrikx, Neil R. Hackett, Ronald G. Crystal, Malcolm A.S. Moore, Zena Werb, David Lyden and Shahin Rafii Nature Medicine8, 841–849
(August 2002); doi:10.1038/nm740
| Abstract | Full Text (HTML/PDF) |
news and views VEGF receptor 1 stimulates stem-cell recruitment and new hope for angiogenesis therapies
Ulf Eriksson and Kari Alitalo Nature Medicine8, 775–777
(August 2002); doi:10.1038/nm0802-775
| Full Text (HTML/PDF) |
article Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling
Takayuki Shindo, Ichiro Manabe, Yasushi Fukushima, Kazuyuki Tobe, Kenichi Aizawa, Saku Miyamoto, Keiko Kawai-Kowase, Nobuo Moriyama, Yasushi Imai, Hayato Kawakami, Hiroaki Nishimatsu, Takashi Ishikawa, Toru Suzuki, Hiroyuki Morita, Koji Maemura, Masataka Sata, Yasunobu Hirata, Masayuki Komukai, Hiroyuki Kagechika, Takashi Kadowaki, Masahiko Kurabayashi and Ryozo Nagai Nature Medicine8, 856–863
(August 2002); doi:10.1038/nm738
| Abstract | Full Text (HTML/PDF) |
July
letter Placental a2-adrenoceptors control vascular development at the interface between mother and embryo
Melanie Philipp, Marc E. Brede, Kerstin Hadamek, Manfred Gessler, Martin J. Lohse and Lutz Hein Nature Genetics31, 311–315
(July 2002); doi:10.1038/ng919
| First Paragraph | Full Text (HTML/PDF) |
article Nitric oxide in the human respiratory cycle
Timothy J. McMahon, Richard E. Moon, Ben P. Luschinger, Martha S. Carraway, Anne E. Stone, Bryant W. Stolp, Andrew J. Gow, John R. Pawloski, Paula Watke, David J. Singel, Claude A. Piantadosi and Jonathan S. Stamler Nature Medicine8, 711–717
(July 2002); doi:10.1038/nm718
| Abstract | Full Text (HTML/PDF) |
news and views Hemoglobin as a chariot for NO bioactivity
Paul Lane and Steven Gross Nature Medicine8, 657–658
(July 2002); doi:10.1038/nm0702-657
| Full Text (HTML/PDF) |
June
letter VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
Hans-Peter Gerber, Ajay K. Malik, Gregg P. Solar, Daniel Sherman, Xiao Huan Liang, Gloria Meng, Kyu Hong, James C. Marsters and Napoleone Ferrara Nature417, 954–958
(June 2002); doi:10.1038/nature00821
| First Paragraph | Full Text (HTML/PDF) |
May
review article POTENTIAL CARDIOPROTECTIVE ACTIONS OF NO-RELEASING ASPIRIN
John L. Wallace, Louis J. Ignarro and Stefano Fiorucci Nature Reviews Drug Discovery1, 375–382
(May 2002); doi:10.1038/nrd794
| Abstract | Full Text (HTML/PDF) |
April
article Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor
Olga V. Volpert, Tetiana Zaichuk, Wei Zhou, Frank Reiher, Thomas A. Ferguson, P. Michael Stuart, Mohammad Amin and Noel P. Bouck Nature Medicine8, 349–357
(April 2002); doi:10.1038/nm0402-349
| Abstract | Full Text (HTML/PDF) |
February
review article SPECIALIZATION OF TUMOUR VASCULATURE
Erkki Ruoslahti Nature Reviews Cancer2, 83–90
(February 2002); doi:10.1038/nrc724
| Abstract | Full Text (HTML/PDF) |
article Steps toward mapping the human vasculature by phage display
Wadih Arap, Mikhail G. Kolonin, Martin Trepel, Johanna Lahdenranta, Marina Cardó-Vila, Ricardo J. Giordano, Paul J. Mintz, Peter U. Ardelt, Virginia J. Yao, Claudia I. Vidal, Limor Chen, Anne Flamm, Heli Valtanen, Lisa M. Weavind, Marshall E. Hicks, Raphael E. Pollock, Gregory H. Botz, Corazon D. Bucana, Erkki Koivunen, Dolores Cahill, Patricia Troncoso, Keith A. Baggerly, Rebecca D. Pentz, Kim-Anh Do, Christopher J. Logothetis and Renata Pasqualini Nature Medicine 8, 121–127
(February 2002); doi:10.1038/nm0202-121
| Abstract | Full Text (HTML/PDF) |
January
commentary Lymphatic endothelium: a new frontier of metastasis research
Marika J. Karkkainen, Taija Mäkinen and Kari Alitalo Nature Cell Biology4, E2
(January 2002); doi:10.1038/ncb0102-e2
| Full Text (HTML/PDF) |
letters to nature Fibulin-5/DANCE is essential for elastogenesis in vivo
Tomoyuki Nakamura, Pilar Ruiz Lozano, Yasuhiro Ikeda, Yoshitaka Iwanaga, Aleksander Hinek, Susumu Minamisawa, Ching-Feng Cheng, Kazuhiro Kobuke, Nancy Dalton, Yoshikazu Takada, Kei Tashiro, John Ross Jr, Tasuku Honjo and Kenneth R. Chien Nature 415, 171–175
(January 2002); doi:10.1038/415171a
| First Paragraph | Full Text (HTML/PDF) |
