article S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide
Takeshi Adachi, Robert M Weisbrod, David R Pimentel, Jia Ying, Victor S Sharov, Christian Schöneich and Richard A Cohen Nature Medicine10, 1200–1207
(November 2004); doi:10.1038/nm1119
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article Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
Jürgen Soutschek, Akin Akinc, Birgit Bramlage, Klaus Charisse, Rainer Constien, Mary Donoghue, Sayda Elbashir, Anke Geick, Philipp Hadwiger, Jens Harborth, Matthias John, Venkitasamy Kesavan, Gary Lavine, Rajendra K. Pandey, Timothy Racie, Kallanthottathil G. Rajeev, Ingo Röhl, Ivanka Toudjarska, Gang Wang, Silvio Wuschko, David Bumcrot, Victor Koteliansky, Stefan Limmer, Muthiah Manoharan and Hans-Peter Vornlocher Nature432, 173–178
(11 November 2004); doi:10.1038/nature03121
| Abstract | Full Text (HTML / PDF) |
October
article Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung
Chun Geun Lee, Holger Link, Peter Baluk, Robert J Homer, Svetlana Chapoval, Vineet Bhandari, Min Jong Kang, Lauren Cohn, Yoon Keun Kim, Donald M McDonald and Jack A Elias Nature Medicine10, 1095–1103
(October 2004); doi:10.1038/nm1105
| Abstract | Full Text (HTML/PDF) |
news and views VEGF obstructs the lungs
Marc E Rothenberg Nature Medicine10, 1041–1042
(October 2004); doi:10.1038/nm1004-1041
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September
article Tumor-infiltrating dendritic cell precursors recruited by a β-defensin contribute to vasculogenesis under the influence of Vegf-A
Jose R Conejo-Garcia, Fabian Benencia, Maria-Cecilia Courreges, Eugene Kang, Alisha Mohamed-Hadley, Ronald J Buckanovich, David O Holtz, Ann Jenkins, Hana Na, Lin Zhang, Daniel S Wagner, Dionyssios Katsaros, Richard Caroll and George Coukos Nature Medicine10, 950–958
(September 2004); doi:10.1038/nm1097
| Abstract | Full Text (HTML/PDF) |
article Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis
Tatiana V Petrova, Terhi Karpanen, Camilla Norrmén, Russell Mellor, Tomoki Tamakoshi, David Finegold, Robert Ferrell, Dontscho Kerjaschki, Peter Mortimer, Seppo Ylä-Herttuala, Naoyuki Miura and Kari Alitalo Nature Medicine10, 974–981
(September 2004); doi:10.1038/nm1094
| Abstract | Full Text (HTML/PDF) |
letters to nature Calcium transients in astrocyte endfeet cause cerebrovascular constrictions
Sean J. Mulligan and Brian A. MacVicar Nature431, 195–199
(09 September 2004); doi:10.1038/nature02827
| First Paragraph | Full Text (HTML / PDF) |
news and views Neurobiology: Feeding the brain
Claire Peppiatt and David Attwell Nature431, 137–138
(09 September 2004); doi:10.1038/431137a
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letter CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation
Jill R Crittenden, Wolfgang Bergmeier, Yanyu Zhang, Crystal L Piffath, Yuqiong Liang, Denisa D Wagner, David E Housman and Ann M Graybiel Nature Medicine10, 982–986
(September 2004); doi:10.1038/nm1098
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article Aβ is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis
Martin C Herzig, David T Winkler, Patrick Burgermeister, Michelle Pfeifer, Esther Kohler, Stephen D Schmidt, Simone Danner, Dorothee Abramowski, Christine Stürchler-Pierrat, Kurt Bürki, Sjoerd G van Duinen, Marion L C Maat-Schieman, Matthias Staufenbiel, Paul M Mathews and Mathias Jucker Nature Neuroscience7, 954–960
(September 2004); doi:10.1038/nn1302
| Abstract | Full Text (HTML/PDF) |
news and views An animal model of vascular amyloidosis
Jorge Ghiso and Thomas Wisniewski Nature Neuroscience7, 902–904
(September 2004); doi:10.1038/nn0904-902
| Full Text (HTML/PDF) |
news and views Unravelling Ras signals in cardiovascular disease
Kenneth R. Chien and Masahiko Hoshijima Nature Cell Biology6, 807–808
(September 2004); doi:10.1038/ncb0904–807
| Full Text (HTML/PDF) |
August
article VEGF links hippocampal activity with neurogenesis, learning and memory
Lei Cao, Xiangyang Jiao, David S Zuzga, Yuhong Liu, Dahna M Fong, Deborah Young and Matthew J During Nature Genetics36, 827–835
(August 2004); doi:10.1038/ng1395
| Abstract | Full Text (HTML/PDF) |
news and views Experiencing VEGF
David A Greenberg and Kunlin Jin Nature Genetics36, 792–793
(August 2004); doi:10.1038/ng0804-792
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research article Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture
Eberhard Durr, Jingyi Yu, Karolina M Krasinska, Lucy A Carver, John R Yates, Jacqueline E Testa III, Phil Oh and Jan E Schnitzer Nature Biotechnology22, 985–992
(August 2004); doi:10.1038/nbt993
| Abstract | Full Text (HTML/PDF) |
brief communication Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity
Lu Chen, Pedram Hamrah, Claus Cursiefen, Qiang Zhang, Bronislaw Pytowski, J Wayne Streilein and M Reza Dana Nature Medicine10, 813–815
(August 2004); doi:10.1038/nm1078
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July
letter Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma
Hsei-Wei Wang, Matthew W B Trotter, Dimitrios Lagos, Dimitra Bourboulia, Stephen Henderson, Taija Mäkinen, Stephen Elliman, Adrienne M Flanagan, Kari Alitalo and Chris Boshoff Nature Genetics36, 687–693
(July 2004); doi:10.1038/ng1384
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brief communication Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus
Young-Kwon Hong, Kimberly Foreman, Jay W Shin, Satoshi Hirakawa, Christine L Curry, David R Sage, Towia Libermann, Bruce J Dezube, Joyce D Fingeroth and Michael Detmar Nature Genetics36, 683–685
(July 2004); doi:10.1038/ng1383
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June
article Reversal of obesity by targeted ablation of adipose tissue
Mikhail G Kolonin, Pradip K Saha, Lawrence Chan, Renata Pasqualini and Wadih Arap Nature Medicine10, 625–632
(June 2004); doi:10.1038/nm1048
| Abstract | Full Text (HTML/PDF) |
news and views Magic bullets melt fat
Marc L Reitman Nature Medicine10, 581–582
(June 2004); doi:10.1038/nm0604-581
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review article The anti-angiogenic basis of metronomic chemotherapy
Robert S. Kerbel and Barton A. Kamen Nature Reviews Cancer4, 423–436
(June 2004); doi:10.1038/nrc1369
| Abstract | Full Text (HTML / PDF) |
brief communication The stalk region of dynamin drives the constriction of dynamin tubes
Yen-Ju Chen, Peijun Zhang, Edward H Egelman and Jenny E Hinshaw Nature Structural and Molecular Biology11, 574–575
(June 2004); doi:10.1038/nsmb762
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article Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy
Phil Oh, Yan Li, Jingyi Yu, Eberhard Durr, Karolina M. Krasinska, Lucy A. Carver, Jacqueline E. Testa and Jan E. Schnitzer Nature429, 629–635
(10 June 2004); doi:10.1038/nature02580
| Abstract | Full Text (HTML / PDF) |
news and views Molecular medicine: The writing is on the vessel wall
Christopher H. Contag and Michael H. Bachmann Nature429, 618–619
(10 June 2004); doi:10.1038/429618a
| Full Text (HTML / PDF) |
May
letters to nature VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model
Mimoun Azzouz, G. Scott Ralph, Erik Storkebaum, Lucy E. Walmsley, Kyriacos A. Mitrophanous, Susan M. Kingsman, Peter Carmeliet and Nicholas D. Mazarakis Nature429, 413–417
(27 May 2004); doi:10.1038/nature02544
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article Regulation of angiogenesis by tissue factor cytoplasmic domain signaling
Mattias Belting, Michael I Dorrell, Staffan Sandgren, Edith Aguilar, Jasimuddin Ahamed, Andrea Dorfleutner, Peter Carmeliet, Barbara M Mueller, Martin Friedlander and Wolfram Ruf Nature Medicine10, 502–509
(May 2004); doi:10.1038/nm1037
| Abstract | Full Text (HTML/PDF) |
letters to nature Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors
Weihai He, Frederick J.-P. Miao, Daniel C.-H. Lin, Ralf T. Schwandner, Zhulun Wang, Jinhai Gao, Jin-Long Chen, Hui Tian and Lei Ling Nature429, 188–193
(13 May 2004); doi:10.1038/nature02488
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news and views Physiology: Orphan detectors of metabolism
Steven C. Hebert Nature429, 143–145
(13 May 2004); doi:10.1038/429143a
| Full Text (HTML / PDF) |
letters to nature Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-α secretion in vitro
Kouichi Ozaki, Katsumi Inoue, Hiroshi Sato, Aritoshi Iida, Yozo Ohnishi, Akihiro Sekine, Hideyuki Sato, Keita Odashiro, Masakiyo Nobuyoshi, Masatsugu Hori, Yusuke Nakamura and Toshihiro Tanaka Nature429, 72–75
(06 May 2004); doi:10.1038/nature02502
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review article Plant cell biology: Signals that control plant vascular cell differentiation
Hiroo Fukuda Nature Reviews Molecular Cell Biology5, 379–391
(May 2004); doi:10.1038/nrm1364
| Abstract | Full Text (HTML / PDF) |
April
letter Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways
Harry Björkbacka, Vidya V Kunjathoor, Kathryn J Moore, Stephanie Koehn, Christine M Ordija, Melinda A Lee, Terry Means, Kristen Halmen, Andrew D Luster, Douglas T Golenbock and Mason W Freeman Nature Medicine10, 416–421
(April 2004); doi:10.1038/nm1008
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letters to nature The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation
Leon H. Parker, Maike Schmidt, Suk-Won Jin, Alane M. Gray, Dimitris Beis, Thinh Pham, Gretchen Frantz, Susan Palmieri, Kenneth Hillan, Didier Y. R. Stainier, Frederic J. de Sauvage and Weilan Ye Nature428, 754–758
(15 April 2004); doi:10.1038/nature02416
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article A new role for Nogo as a regulator of vascular remodeling
Lisette Acevedo, Jun Yu, Hediye Erdjument-Bromage, Robert Qing Miao, Ji-Eun Kim, David Fulton, Paul Tempst, Stephen M Strittmatter and William C Sessa Nature Medicine10, 382–388
(April 2004); doi:10.1038/nm1020
| Abstract | Full Text (HTML/PDF) |
news and views Nogo puts the brake on vascular lesions
Elaine W Raines Nature Medicine10, 348–349
(April 2004); doi:10.1038/nm0404-348
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review article Endothelial cell-cell junctions: happy together
Elisabetta Dejana Nature Reviews Molecular Cell Biology5, 261–270
(April 2004); doi:10.1038/nrm1357
| Abstract | Full Text (HTML / PDF) |
March
letters to nature The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
Igor Garkavtsev, Sergey V. Kozin, Olga Chernova, Lei Xu, Frank Winkler, Edward Brown, Gene H. Barnett and Rakesh K. Jain Nature428, 328–332
(18 March 2004); doi:10.1038/nature02329
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article Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470
Ronit Satchi-Fainaro, Mark Puder, John W Davies, Hai T Tran, David A Sampson, Arin K Greene, Gabriel Corfas and Judah Folkman Nature Medicine10, 255–261
(March 2004); doi:10.1038/nm1002
| Abstract | Full Text (HTML/PDF) |
February
article A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase
Yoshiaki Kise, Sang Won Lee, Sang Gyu Park, Shuya Fukai, Toru Sengoku, Ryohei Ishii, Shigeyuki Yokoyama, Sunghoon Kim and Osamu Nureki Nature Structural and Molecular Biology11, 149–156
(February 2004); doi:10.1038/nsmb722
| Abstract | Full Text (HTML/PDF) |
brief communication Pathology: Cancer cells compress intratumour vessels
Timothy P. Padera, Brian R. Stoll, Jessica B. Tooredman, Diane Capen, Emmanuelle di Tomaso and Rakesh K. Jain Nature427, 695
(19 February 2004); doi:10.1038/427695a
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review article Oxygen therapeutics: can we tame haemoglobin?
Abdu I. Alayash Nature Reviews Drug Discovery3, 152–159
(February 2004); doi:10.1038/nrd1307
| Abstract | Full Text (HTML / PDF) |
letters to nature Identification of an angiogenic factor that when mutated causes susceptibility to Klippel-Trenaunay syndrome
Xiao-Li Tian, Rajkumar Kadaba, Sun-Ah You, Mugen Liu , Ayse Anil Timur, Lin Yang, Qiuyun Chen, Przemyslaw Szafranski, Shaoqi Rao, Ling Wu, David E. Housman, Paul E. DiCorleto, David J. Driscoll, Julian Borrow and Qing Wang Nature427, 640–645
(12 February 2004); doi:10.1038/nature02320
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news and views Medicine: Genetic spotlight on a blood defect
Diether Lambrechts and Peter Carmeliet Nature427, 592–594
(12 February 2004); doi:10.1038/427592a
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brief communication Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
Christopher G Willett, Yves Boucher, Emmanuelle di Tomaso, Dan G Duda, Lance L Munn, Ricky T Tong, Daniel C Chung, Dushyant V Sahani, Sanjeeva P Kalva, Sergey V Kozin, Mari Mino, Kenneth S Cohen, David T Scadden, Alan C Hartford, Alan J Fischman, Jeffrey W Clark, David P Ryan, Andrew X Zhu, Lawrence S Blaszkowsky, Helen X Chen, Paul C Shellito, Gregory Y Lauwers and Rakesh K Jain Nature Medicine10, 145–147
(February 2004); doi:10.1038/nm988
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article Reactive oxygen species impair Slo1 BK channel function by altering cysteine-mediated calcium sensing
Xiang Dong Tang, Maria L Garcia, Stefan H Heinemann and Toshinori Hoshi Nature Structural and Molecular Biology11, 171–178
(February 2004); doi:10.1038/nsmb725
| Abstract | Full Text (HTML/PDF) |
January
article Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
Marika J Karkkainen, Paula Haiko, Kirsi Sainio, Juha Partanen, Jussi Taipale, Tatiana V Petrova, Michael Jeltsch, David G Jackson, Marja Talikka, Heikki Rauvala, Christer Betsholtz and Kari Alitalo Nature Immunology5, 74–80
(January 2004); doi:10.1038/ni1013
| Abstract | Full Text (HTML/PDF) |
news and views Genes tell lymphatics to sprout or not
Judah Folkman and Arja Kaipainen Nature Immunology5, 11–12
(January 2004); doi:10.1038/ni0104-11
| Full Text (HTML/PDF) |
review article Lymphatic vasculature development
Guillermo Oliver Nature Reviews Immunology4, 35–45
(January 2004); doi:10.1038/nri1258
| Abstract | Full Text (HTML / PDF) |
article Chemokine-mediated interaction of hematopoietic progenitors with the
bone marrow vascular niche is required for thrombopoiesis
Scott T Avecilla, Koichi Hattori, Beate Heissig, Rafael Tejada, Fang Liao,
Koji Shido, David K Jin, Sergio Dias, Fan Zhang, Travis E Hartman, Neil
R Hackett, Ronald G Crystal, Larry Witte, Daniel J. Hicklin, Peter Bohlen,
Dan Eaton, David Lyden, Fredric de Sauvage and Shahin Rafii Nature Medicine10, 64–71
(January 2004); doi:10.1038/nm973
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